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https://www.readbyqxmd.com/read/27922030/histamine-2-receptor-antagonist-cannot-prevent-recurrent-peptic-ulcers-in-patients-with-atherosclerotic-diseases-who-receive-platelet-adp-receptor-antagonist-monotherapy-a-randomized-controlled-double-blind-and-double-dummy-trial
#1
Ping-I Hsu, Deng-Chyang Wu, Feng-Woei Tsay, Jin-Shiung Cheng, Chun-Peng Liu, Kwok-Hung Lai, Wen-Chi Chen, Huay-Min Wang, Tzung-Jiun Tsai, Kuo-Wang Tsai, Sung-Shuo Kao
OBJECTIVES: Proton pump inhibitor can effectively prevent recurrent peptic ulcers among atherosclerotic patients receiving clopidogrel monotherapy. However, the interaction between proton pump inhibitors and clopidogrel has raised concerns over the safety of combined use of the two medicines in clinical practice. The aims of this randomized-controlled, double-blind and double-dummy trial were to investigate the efficacy of histamine-2 receptor antagonist (H2RA) in the prevention of recurrent peptic ulcer in patients undergoing thienopyridine monotherapy...
December 6, 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27900870/-hemosuccus-pancreaticus-rare-complication-of-chronic-pancreatitis
#2
Igor Šturdík, Martin Kužma, Zuzana Kužmová, Tomáš Koller, Vladimír Javorka, Tibor Hlavatý, Juraj Payer
Hemosuccus pancreaticus is a rare cause of upper digestive tract bleeding, it is hemorrhage to the pancreatic duct. A case report is about 56-years old man who was repeatedly hospitalized and suffered from melena and enterorrhagia during 3 years. Imaging studies did not clearly identified etiology of bleeding or source of hemorrhage was wrong identified. Finally, hemosuccus pancreaticus from collaterals of pseudoaneurysm after embolization was suspected because of repeating hemorrhage and embolization of a gastroduodenal artery in history...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27885231/two-elderly-patients-with-difficult-to-treat-acquired-hemophilia-a
#3
Makoto Saito, Masanobu Morioka
We herein report the cases of two elderly patients with acquired hemophilia A (AHA) for whom treatment was difficult.An 89-year-old woman (Case 1) was admitted to our department with subcutaneous hemorrhage and melena. Her activated partial thromboplastin time (APTT), factor VIII activity, and factor VIII inhibitor level were 127.7 seconds, 1.0%, and 48 BU/mL, respectively, which was suggestive of AHA. The administration of prednisolone (PSL 0.5 mg/kg) was initiated. After 3 weeks, PSL was combined with cyclophosphamide (CPA 50 mg)...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27876976/variation-in-clinical-markers-in-cattle-naturally-infected-with-bovine-tropical-theileriosis
#4
Rahul Parashar, Vikrant Sudan, Amit Kumar Jaiswal, Daya Shanker
124 cattle naturally infected with Theileria annulata were inspected for clinical markers. Clinical manifestations of general weakness, reduced appetite, pyrexia reaching 40-42 °C and lachrymal discharge were seen in more than 75 % of the infected animals. Presence of ticks on body, general dullness and depression, recumbency/prostration, oedema of dependent body parts, diarrhea, hypersalivation, pale mucous membranes and yellow colored urine were revealed by more than 50 % of the infected animals. Clinical manifestations of dehydration, abdominal distension/ascites, jaundice and haemoglobinuria were revealed by more than 25 % of the infected animals less than 25 % of the infected animals showed clinical manifestations of exophthalmia, constipation, melena, buccal cavity erosions, congested mucous membranes, nasal discharge and tachypnoea...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27871022/vascular-targeted-photodynamic-therapy-of-gastric-antral-vascular-ectasia-gave
#5
Haixia Qiu, Yongping Mao, Jing Zeng, Ying Wang, Jiaying Zhang, Naiyang Huang, Qingsen Liu, Yunsheng Yang, Enqiang Linghu, Ying Gu
BACKGROUND AND STUDY AIM: Vascular-targeted photodynamic therapy (V-PDT) has been used for several benign vascular diseases. The aim of this pilot study was to demonstrate the potential benefits of VPDT in the treatment of gastric antral vascular ectasia (GAVE). PATIENTS AND METHODS: Data from patients with GAVE (n=5) who underwent endoscopic V-PDT were analyzed retrospectively. Pre- and post-V-PDT clinical and endoscopic features, hemoglobin levels, and transfusion requirement were compared...
October 29, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27864300/oral-and-gastrointestinal-symptomatic-metastases-as-initial-presentation-of-lung-cancer
#6
Jenifer Jeba, Selvamani Backianathan, Gunadala Ishitha, Ashish Singh
Metastasis to the tongue, duodenum or pancreas from primary lung cancer is uncommon. Primary lung cancer presenting with symptoms related to metastases at these sites, at initial presentation is extremely rare. We report a 45-year-old man with disseminated lung malignancy who presented with dyspepsia, melena, symptoms due to anaemia and swelling in the tongue. Oral examination revealed a hard submucosal anterior tongue lesion. Biopsies from the tongue lesion and the duodenal ulcer seen on upper gastrointestinal endoscopy were suggestive of metastasis from lung primary...
November 18, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27843431/two-patients-with-large-colonic-lipomas-for-which-endoscopic-unroofing-was-ineffective
#7
Yuichi Tomiki, Koichiro Niwa, Kiichi Nagayasu, Yu Okazawa, Shingo Ito, Ryosuke Ichikawa, Hisashi Ro, Shun Ishiyama, Kiichi Sugimoto, Kazuhiro Sakamoto
Endoscopic unroofing is effective for treating large colonic lipomas. However, additional endoscopic resection is occasionally required when the outcomes of initial unroofing are incomplete. The colonoscopy of an 82-year-old woman with abdominal pain revealed a yellowish lipoma of about 20 mm in the transverse colon. The mass was treated by unroofing, but a follow-up colonoscopy 5 days later revealed residual lipoma. One month later, the regenerated surface had become covered with mucosa, and the status of the lipoma had returned to that before unroofing...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27843428/a-rare-case-of-gastric-variceal-hemorrhage-secondary-to-infiltrative-b-cell-lymphoma
#8
Adrienne Lenhart, Juan Fernandez-Castillo, Keith Mullins, Reena Salgia
Portal hypertension commonly arises in the setting of advanced liver cirrhosis and is the consequence of increased resistance within the portal vasculature. Less commonly, left-sided noncirrhotic portal hypertension can develop in a patient secondary to isolated obstruction of the splenic vein. We present a rare case of left-sided portal hypertension and isolated gastric varices in a patient with large B-cell lymphoma, who was treated with splenic artery embolization. The patient is a 73-year-old male with no previous history of liver disease, who presented with coffee ground emesis and melena...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27836330/evaluation-of-rosemont-criteria-for-non-calcific-chronic-pancreatitis-nccp-based-on-histopathology-a-retrospective-study
#9
Guru Trikudanathan, Satish Munigala, Usman Barlass, Ahmad Malli, Yusheng Han, Miroslav Sekulic, Melena Bellin, Srinath Chinnakotla, Ty Dunn, Timothy Pruett, Gregory Beilman, Jose-Vega Peralta, Mustafa Arain, Stuart Amateau, Shawn Mallery, Martin L Freeman, Rajeev Attam
BACKGROUND: Rosemont classification for chronic pancreatitis has not been evaluated specifically in non-calcific chronic pancreatitis (NCCP) patients and to this date, it has not been correlated with the gold standard namely histopathology. OBJECTIVE: To assess the correlation of EUS Rosemont criteria for NCCP with histopathology from surgical specimens and evaluate the impact of age, sex, BMI, smoking and alcohol on Rosemont classification. METHODS: Adult patients undergoing TPIAT for NCCP between July 2009 and January 2013 were identified from our institutional database...
October 26, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/27830096/hemorrhage-from-extra-antral-gastric-antral-vascular-ectasia-in-a-patient-with-duodenal-heterotopic-gastric-mucosa
#10
John Gubatan, Nathan Raines, Hasan Khosravi, Tracy L Challies, Tyler M Berzin
Gastric antral vascular ectasias (GAVE) have been increasingly recognized as an uncommon cause of chronic gastrointestinal bleeding and anemia, although their underlying pathogenesis is not completely well understood. Heterotopic gastric mucosa (HGM) has been reported to occur at various sites along the gastrointestinal tract and although relatively common, it is often asymptomatic. We report a case of a 60-year-old woman with a prior history of GAVE who developed melena and symptomatic anemia during her hospitalization following cardiac catheterization...
2016: Case Reports in Gastrointestinal Medicine
https://www.readbyqxmd.com/read/27811622/therapeutic-endoscopy-for-the-control-of-non-variceal-upper-gastrointestinal-bleeding-in-children-a-case-series
#11
Anna M Banc-Husu, Nuzhat A Ahmad, Vinay Chadrasekhara, Gregory G Ginsberg, David L Jaffe, Michael L Kochman, Michael Rajala, Petar Mamula
INTRODUCTION: Gastrointestinal bleeding is one of the most common indications for urgent endoscopy in the pediatric setting. The majority of these procedures are performed for control of variceal bleeding, with very few performed for non-variceal upper gastrointestinal (NVUGI) bleeding. The data on therapeutic endoscopy for NVUGI are very sparse. The aims of our study were to review our experience with NVUGI bleeding, describe technical aspects and outcomes of therapeutic endoscopy, and determine gastroenterology fellows' training opportunities according to the national training guidelines...
November 2, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27803496/left-atrial-to-esophageal-fistula-a-case-report-and-literature-review
#12
Muhammad Yasir Khan, Waqas Javed Siddiqui, Praneet S Iyer, Ahmed Dirweesh, Nigahus Karabulut
BACKGROUND Left atrial to esophageal fistula (LAEF) is a rare fatal complication of radiofrequency ablation (RFA) for atrial fibrillation and is associated with high mortality. Clinical features can be nonspecific and include fever, dysphagia, upper gastrointestinal (GI) bleeding, sepsis, and embolic stroke a after recent history of RFA for atrial fibrillation. CASE REPORT  A 57-year-old Caucasian male was brought to the emergency department (ED) by his family because of an altered mental status. He had undergone a radiofrequency ablation for paroxysmal atrial fibrillation three weeks earlier...
November 2, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27803086/advanced-gastric-cancer-linitis-plastica-presented-with-disseminated-intravascular-coagulation
#13
Sehem Ghazala, Jawad Bilal, Irbaz Bin Riaz
An old man was found unconscious; on admission found to have disseminated intravascular coagulation with concern of upper gastrointestinal bleed after he was found to have melena. Esophagogastroduodenoscopy on admission showed diffuse thickened gastric folds, and biopsy showed mucosal oedema. Bone marrow biopsy concerning for lymphoma was obtained showed adenocarcinoma. MRI of the abdomen was significant for diffuse gastric wall thickening. A repeat endoscopic ultrasound showed a diffuse gastric wall thickening of 15 mm and submucosal tunneling technique biopsy suggested high-grade, invasive, signet ring adenocarcinoma of the stomach...
November 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27800543/a-48-year-old-man-with-epigastric-pain-and-melena
#14
Narvir Singh Chauhan
No abstract text is available yet for this article.
November 2016: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/27800519/clofazimine-enteropathy-a-rare-and-underrecognized-complication-of-mycobacterial-therapy
#15
Winnie Szeto, Monica T Garcia-Buitrago, Lilian Abbo, Joseph D Rosenblatt, Baharak Moshiree, Michele I Morris
Clofazimine-induced crystal-storing histiocytosis is a rare complication of treatment previously reported in dermatology literature as a complication of leprosy therapy. We report a case of disseminated Mycobacterium abscessus requiring treatment with high-dose oral clofazimine resulting in enteropathy in a patient who presented with abdominal pain, malnutrition, and melena.
September 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27795783/-overdose-in-vitamin-k-antagonists-administration-in-dakar-epidemiological-clinical-and-evolutionary-aspects
#16
Khadidiatou Dia, Simon Antoine Sarr, Mohamed Cherif Mboup, Djibril Marie Ba, Pape Diadie Fall
Vitamin K antagonists (VKA) are widely used for the prevention and curative treatment of thromboembolic events. This study aims to describe the epidemiological, clinical and evolutionary aspects of overdose in Vitamin K antagonists administration and determine its hemorrhagic factors. We conducted a monocentric cross-sectional descriptive study at the Principal Hospital in Dakar. All patients with an INR greater than 5 were included. We studied patients' gender and age, VKA used, drug use period, indications, INR value, associated drugs, presence of hemorrhage, immediate management and evolution...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27776486/bleeding-downhill-esophageal-varices-associated-with-benign-superior-vena-cava-obstruction-case-report-and-literature-review
#17
Michael Loudin, Sharon Anderson, Barry Schlansky
BACKGROUND: Proximal or 'downhill' esophageal varices are a rare cause of upper gastrointestinal hemorrhage. Unlike the much more common distal esophageal varices, which are most commonly a result of portal hypertension, downhill esophageal varices result from vascular obstruction of the superior vena cava (SVC). While SVC obstruction is most commonly secondary to malignant causes, our review of the literature suggests that benign causes of SVC obstruction are the most common cause actual bleeding from downhill varices...
October 24, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27760437/a-novel-hemostatic-powder-for-upper-gastrointestinal-bleeding-a-multicenter-study-the-graphe-registry
#18
Sami Haddara, Jeremie Jacques, Stéphane Lecleire, Julien Branche, Sarah Leblanc, Yann Le Baleur, Jocelyn Privat, Laurent Heyries, Philippe Bichard, Philippe Granval, Ulriikka Chaput, Stephane Koch, Jonathan Levy, Bruno Godart, Antoine Charachon, Jean-François Bourgaux, Elodie Metivier-Cesbron, Edouard Chabrun, Vincent Quentin, Bastien Perrot, Geoffroy Vanbiervliet, Emmanuel Coron
: Background and study aims: The hemostatic powder TC-325 (Hemospray; Cook Medical, Winston-Salem, North Carolina, USA) has shown promising results in the treatment of upper gastrointestinal bleeding (UGIB) in expert centers in pilot studies. The aim of this study was to evaluate the feasibility and efficacy of TC-325 in a large prospective registry of use in routine practice. Patients and methods: The data of all patients treated with TC-325 were prospectively collected through a national registry...
December 2016: Endoscopy
https://www.readbyqxmd.com/read/27752605/a-revised-risk-analysis-of-stress-ulcers-in-burn-patients-receiving-ulcer-prophylaxis
#19
Young Hwan Choi, Jong Ho Lee, Jae Jun Shin, Young Soon Cho
OBJECTIVE: Most of the literature about Curling's ulcer was published from 1960 through 1980. Therefore, an updated study of Curling's ulcer is needed. We analyzed the risk factors affecting ulcer incidence in burn patients. METHODS: We retrospectively analyzed the medical records of burn patients who were admitted to two burn centers. We collected information about the general characteristics of patients, burn area size, abbreviated burn severity index, whether surgery was performed, endoscopy results, and the total body surface area (TBSA)...
December 2015: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/27752380/bronchial-leech-infestation-in-a-15-year-old-female
#20
Mohammad Ashkan Moslehi, Mohammad Hadi Imanieh, Ali Adib
Foreign body aspiration (FBA) is a common incidence in young children. Leeches are rarely reported as FBA at any age. This study describes a 15-year-old female who presented with hemoptysis, hematemesis, coughs, melena, and anemia seven months prior to admission. Chest X-ray showed a round hyperdensity in the right lower lobe. A chest computed tomography (CT) demonstrated an area of consolidation and surrounding ground glass opacities in the right lower lobe. Hematological investigations revealed anemia. Finally, bronchoscopy was performed and a 5 cm leech was found within the right B7-8 bronchus and removed by forceps and a Dormia basket...
2016: Case Reports in Pediatrics
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