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https://www.readbyqxmd.com/read/28520812/the-effect-of-platelet-rich-plasma-on-osseous-healing-in-dogs-undergoing-high-tibial-osteotomy
#1
Samuel P Franklin, Emily E Burke, Shannon P Holmes
OBJECTIVES: The purpose of this study was to investigate whether platelet-rich plasma (PRP) enhances osseous healing in conjunction with a high tibial osteotomy in dogs. STUDY DESIGN: Randomized controlled trial. METHODS: Sixty-four client-owned pet dogs with naturally occurring rupture of the anterior cruciate ligament and that were to be treated with a high tibial osteotomy (tibial plateau leveling osteotomy) were randomized into the treatment or control group...
2017: PloS One
https://www.readbyqxmd.com/read/28515057/delaying-acl-reconstruction-and-treating-with-exercise-therapy-alone-may-alter-prognostic-factors-for-5-year-outcome-an-exploratory-analysis-of-the-kanon-trial
#2
Stephanie R Filbay, Ewa M Roos, Richard B Frobell, Frank Roemer, Jonas Ranstam, L Stefan Lohmander
AIM: Identify injury-related, patient-reported and treatment-related prognostic factors for 5-year outcomes in acutely ACL-ruptured individuals managed with early reconstruction plus exercise therapy, exercise therapy plus delayed reconstruction or exercise therapy alone. METHODS: Exploratory analysis of the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559). Relationships between prognostic factors (baseline cartilage, meniscus and osteochondral damage, baseline extension deficit, baseline patient-reported outcomes, number of rehabilitation visits, graft/contralateral ACL rupture, non-ACL surgery and ACL treatment strategy) and 5-year Knee Injury and Osteoarthritis Outcome Score (KOOS) pain, symptoms, sport/recreation and quality of life (QOL) scores were explored using multivariable linear regression...
May 17, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28510477/performance-based-outcomes-after-anterior-cruciate-ligament-reconstruction-in-professional-athletes-differ-between-sports
#3
Harry T Mai, Danielle S Chun, Andrew D Schneider, Brandon J Erickson, Ryan D Freshman, Benjamin Kester, Nikhil N Verma, Wellington K Hsu
BACKGROUND: Excellent outcomes have been reported for anterior cruciate ligament (ACL) reconstruction (ACLR) in professional athletes in a number of different sports. However, no study has directly compared these outcomes between sports. PURPOSE: To determine if differences in performance-based outcomes exist after ACLR between professional athletes of each sport. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: National Football League (NFL), National Basketball Association (NBA), National Hockey League (NHL), and Major League Baseball (MLB) athletes undergoing primary ACLR for an acute rupture were identified through an established protocol of injury reports and public archives...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28506133/clinical-outcomes-following-surgically-repaired-bucket-handle-meniscus-tears
#4
Michael J Moses, David E Wang, Maxwell Weinberg, Eric J Strauss
OBJECTIVES: Meniscus tears are one of the most common knee injuries. Our goal is to investigate the failure rate for surgically repaired bucket-handle meniscus tears and compare clinical outcomes of repairs that failed versus those that did not, at a minimum 2-year follow-up interval. METHODS: 51 patients were identified in this retrospective cohort study who experienced bucket-handle meniscus tears that were isolated or with concomitant ACL injury. Inclusion criteria included age range from 13-55 years, confirmed bucket-handle meniscus tear by MRI and intraoperatively, and at least two-years of post-operative follow-up following index repair...
May 16, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28502387/anterolateral-ligament-reconstruction-techniques-biomechanics-and-clinical-outcomes-a-systematic-review
#5
REVIEW
Nicholas N DePhillipo, Mark E Cinque, Jorge Chahla, Andrew G Geeslin, Robert F LaPrade
PURPOSE: To perform a systematic review of the described anterolateral ligament (ALL) reconstruction techniques, biomechanical performance, and clinical outcomes of ALL reconstruction in the setting of concurrent anterior cruciate ligament (ACL) reconstruction. METHODS: A systematic review was performed according to PRISMA guidelines using the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, PubMed, MEDLINE, and Embase, from 1980 to present...
May 11, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28498226/anterior-cruciate-ligament-injury-return-to-play-function-and-long-term-considerations
#6
Fernando Sepúlveda, Luis Sánchez, Eduardo Amy, William Micheo
Anterior cruciate ligament tears are common and affect young individuals who participate in jumping and pivoting sports. After injury many individuals undergo ligament reconstruction (ACLR) but do not return to play, suffer recurrent injury and osteoarthritis. Outcome studies show that after ACLR, 81% of individuals return to sports, 65% return to their preinjury level and 55% return to competitive sports. Systematic reviews place the risk of ipsilateral retears at 5.8% and contralateral injuries at 11.8%, with recent reports of over 20% failure rate...
May 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28493217/what-is-the-mid-term-failure-rate-of-revision-acl-reconstruction-a-systematic-review
#7
Alberto Grassi, Christopher Kim, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini, Annunziato Amendola
BACKGROUND: When anterior cruciate ligament (ACL) reconstruction fails, a revision procedure may be performed to improve knee function, correct instability, and allow return to activities. The results of revision ACL reconstruction have been reported to produce good but inferior patient-reported and objective outcomes compared with primary ACL reconstruction, but the degree to which this is the case varies widely among published studies and may be influenced by heterogeneity of patients, techniques, and endpoints assessed...
May 10, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28485509/the-biologic-response-of-human-anterior-cruciate-ligamentocytes-on-collagen-patches-to-platelet-rich-plasma-formulations-with-and-without-leucocytes
#8
Anna M Krismer, Romina S Cabra, Rahel D May, Daniela A Frauchiger, Sandro Kohl, Sufian S Ahmad, Benjamin Gantenbein
Due to the poor self-healing capacities of the anterior cruciate ligament, previous primary repair attempts have failed. To enhance biologic healing, platelet rich plasma and collagen scaffold have shown promise in animal models. Platelet rich plasma (PRP) is already used in several clinical applications although outcomes are quite debated. The purpose of this study was to examine the effects of different PRP formulations during 21 days: with leucocytes and pure PRP on human anterior cruciate ligament-derived ligamentocytes grown on collagen patches in 3D cell cultures in vitro...
May 9, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28483655/visual-utilization-during-postural-control-in-anterior-cruciate-ligament-deficient-reconstructed-patients-systematic-reviews-meta-analyses
#9
REVIEW
Erik A Wikstrom, Kyeongtak Song, Brian G Pietrosimone, J Troy Blackburn, Darin A Padua
OBJECTIVE: To determine if anterior cruciate ligament deficient (ACL-D) individuals and individuals with a reconstructed anterior cruciate ligament (ACL-R) rely more heavily on visual information to maintain postural control. DATA SOURCES: PubMed, CINAHL, and SPORTDiscus databases were searched from their earliest available date to May 24, 2016 using the combination of key words. STUDY SELECTION: Articles were included if they reported any instrumented static single leg balance outcome in both a patient and control sample...
May 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28477270/there-is-no-difference-between-quadriceps-and-hamstring-tendon-autografts-in-primary-anterior-cruciate-ligament-reconstruction-a-2-year-patient-reported%C3%A2-outcome-study
#10
Armin Runer, Guido Wierer, Elmar Herbst, Caroline Hepperger, Mirco Herbort, Peter Gföller, Christian Hoser, Christian Fink
PURPOSE: Graft choice for anterior cruciate ligament (ACL) reconstruction is crucial, however the optimal graft source remains a topic of controversy. The purpose of this study is to compare subjective and functional patient-reported outcomes (PRO) after single-bundle ACL reconstruction using quadriceps tendon (QT) or hamstring tendon (HT) autografts for single-bundle ACL reconstruction. We hypothesize that there is no difference in patient-reported functional outcomes after ACL reconstruction using either HT- or QT autograft...
May 5, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28477147/high-interspecimen-variability-in-engagement-of-the-anterolateral-ligament-an-in-vitro-cadaveric-study
#11
REVIEW
Robert N Kent, James F Boorman-Padgett, Ran Thein, Jelle P van der List, Danyal H Nawabi, Thomas L Wickiewicz, Carl W Imhauser, Andrew D Pearle
BACKGROUND: Anterolateral ligament (ALL) reconstruction as an adjunct to anterior cruciate ligament (ACL) reconstruction remains a subject of clinical debate. This uncertainty may be driven in part by a lack of knowledge regarding where, within the range of knee motion, the ALL begins to carry force (engages). QUESTIONS/PURPOSES: (1) Does the ALL engage in the ACL-intact knee; and (2) where within the range of anterior tibial translation occurring in the ACL-sectioned knee does the ALL engage? METHODS: A robotic manipulator was used to measure anterior tibial translation, ACL forces, and ALL forces in 10 fresh-frozen cadaveric knees (10 donors; mean age, 41 ± 16 years; range, 20-64 years; eight male) in response to applied multiplanar torques...
May 5, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28476359/editorial-commentary-size-does-matter-anterior-cruciate-ligament-graft-diameter-affects-biomechanical-and-clinical-outcomes
#12
EDITORIAL
Mark Steiner
Anterior cruciate ligament (ACL) graft strength is related to graft diameter and how ACL grafts heal. All grafts appear to lose strength during healing. Clinical studies have documented that hamstring grafts less than 8 mm wide are more vulnerable to failure. Tripling the semitendinosus allows to increase the graft diameter and strength. A recent study documents a semitendinosus tripling technique with excellent clinical results.
May 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28473996/return-to-sport-in-the-younger-patient-with-anterior-cruciate-ligament-reconstruction
#13
Kate E Webster, Julian A Feller, Timothy S Whitehead, Gregory D Myer, Peter B Merory
BACKGROUND: Although anterior cruciate ligament (ACL) reconstruction is generally regarded as a successful procedure, only 65% of patients return to their preinjury sport. While return-to-sport rates are likely higher in younger patients, there is a paucity of data that focus on the younger patient and their return-to-sport experience after ACL reconstruction. PURPOSE: To investigate a range of return-to-sport outcomes in younger athletes who had undergone ACL reconstruction surgery...
April 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28471382/decrease-of-mir-195-promotes-chondrocytes-proliferation-and-maintenance-of-chondrogenic-phenotype-via-targeting-fgf-18-pathway
#14
Yong Wang, Tao Yang, Yadong Liu, Wei Zhao, Zhen Zhang, Ming Lu, Weiguo Zhang
Slow growth and rapid loss of chondrogenic phenotypes are the major problems affecting chronic cartilage lesions. The role of microRNA-195 (miR-195) and its detailed working mechanism in the fore-mentioned process remains unknown. Fibroblastic growth factor 18 (FGF-18) plays a key role in cartilage homeostasis; whether miR-195 could regulate FGF-18 and its downstream signal pathway in chondrocyte proliferation and maintenance of chondrogenic phenotypes still remains unclear. The present research shows elevated miR-195 but depressed FGF-18 expressed in joint fluid specimens of 20 patients with chronic cartilage lesions and in CH1M and CH3M chondrocytes when compared with that in joint fluid specimens without cartilage lesions and in CH1W and CH2W chondrocytes, respectively...
May 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28467122/return-to-play-and-decreased-performance-after-anterior-cruciate-ligament-reconstruction-in-national-football-league-defensive-players
#15
Connor R Read, Kyle T Aune, E Lyle Cain, Glenn S Fleisig
BACKGROUND: Anterior cruciate ligament (ACL) injuries occur commonly in football. Recent work has reported ACL reconstruction (ACLR) as one of several orthopaedic procedures with unfavorable outcomes for professional athletes. The performance impact to defensive players after surgery has not been quantified. PURPOSE: To quantify the effect of ACLR on the performance of defensive players by comparing them to a cohort of matched controls as well as to measure the effect of ACLR on athletes' career length in the National Football League (NFL)...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28463915/return-to-play-and-patient-satisfaction-after-acl-reconstruction-study-with-minimum-2-year-follow-up
#16
Benedict U Nwachukwu, Pramod B Voleti, Patricia Berkanish, Brenda Chang, Matthew R Cohn, Riley J Williams, Answorth A Allen
BACKGROUND: Return to play and patient satisfaction after anterior cruciate ligament reconstruction (ACLR) have been inconsistently studied. The purposes of this study were to (1) investigate rates and predictors of return to play after ACLR, (2) evaluate patient satisfaction after ACLR, and (3) analyze the relationship between return to play and satisfaction with the result of ACLR. METHODS: Eligible patients were active athletes included in an institutional ACL registry who had undergone ACLR and had been followed for a minimum of 2 years...
May 3, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28460194/graft-diameter-as-a-predictor-for-revision-anterior-cruciate-ligament-reconstruction-and-koos-and-eq-5d-values-a-cohort-study-from-the-swedish-national-knee-ligament-register-based-on-2240-patients
#17
Thorkell Snaebjörnsson, Eric Hamrin Senorski, Olufemi R Ayeni, Eduard Alentorn-Geli, Ferid Krupic, Fredrik Norberg, Jón Karlsson, Kristian Samuelsson
BACKGROUND: Anterior cruciate ligament (ACL) reconstruction (ACLR) using a hamstring tendon (HT) autograft is an effective and widespread method. Recent studies have identified a relationship between the graft diameter and revision ACLR. PURPOSE: To evaluate the influence of the graft diameter on revision ACLR and patient-reported outcomes in patients undergoing primary ACLR using HT autografts. STUDY DESIGN: Cohort study; Level of evidence, 2...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28459885/a-statistically-compiled-test-battery-for-feasible-evaluation-of-knee-function-after-rupture-of-the-anterior-cruciate-ligament-derived-from-long-term-follow-up-data
#18
Lina Schelin, Eva Tengman, Patrik Ryden, Charlotte Häger
PURPOSE: Clinical test batteries for evaluation of knee function after injury to the Anterior Cruciate Ligament (ACL) should be valid and feasible, while reliably capturing the outcome of rehabilitation. There is currently a lack of consensus as to which of the many available assessment tools for knee function that should be included. The present aim was to use a statistical approach to investigate the contribution of frequently used tests to avoid redundancy, and filter them down to a proposed comprehensive and yet feasible test battery for long-term evaluation after ACL injury...
2017: PloS One
https://www.readbyqxmd.com/read/28458784/evaluating-the-functional-results-and-complications-of-autograft-vs-allograft-use-for-reconstruction-of-the-anterior-cruciate-ligament-a-systematic-review
#19
REVIEW
Ojas Pujji, Nikita Keswani, Naomi Collier, Marion Black, Lucy Doos
The aim of our review is to identify the reconstruction technique that has a superior functional outcome and decreased number of complications for the anterior cruciate ligament (ACL). We have divided our review into 2 sections. Our primary question evaluates the functional results and complications of autografts compared to allografts for ACL reconstruction. Our subsidiary question evaluates the functional results and complications of bone-patellar tendon-bone (BPTB) autografts compared to hamstring tendon autografts...
February 20, 2017: Orthopedic Reviews
https://www.readbyqxmd.com/read/28455730/knee-abduction-affects-greater-magnitude-of-change-in-acl-and-mcl-strains-than-matched-internal-tibial-rotation-in-vitro
#20
Nathaniel A Bates, Rebecca J Nesbitt, Jason T Shearn, Gregory D Myer, Timothy E Hewett
BACKGROUND: Anterior cruciate ligament (ACL) injures incur over USD 2 billion in annual medical costs and prevention has become a topic of interest in biomechanics. However, literature conflicts persist over how knee rotations contribute to ACL strain and ligament injury. To maximize the efficacy of ACL injury prevention, the effects of underlying mechanics need to be better understood. QUESTIONS/PURPOSES: We applied robotically controlled, in vivo-derived kinematic stimuli to the knee to assess ligament biomechanics in a cadaver model...
April 28, 2017: Clinical Orthopaedics and related Research
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