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https://www.readbyqxmd.com/read/29444321/left-ventricular-regional-dyssynchrony-predicts-improvements-in-moderate-ischaemic-mitral-regurgitation-after-off-pump-coronary-artery-bypass
#1
Xiaotian Sun, Guoqian Huang, Jiechun Huang, Meng Shi, Fangrui Wang, Liewen Pang, Yiqing Wang
OBJECTIVES: The aim of this study was to explore the predictors of the improvement in moderate ischaemic mitral regurgitation (IMR) after off-pump coronary artery bypass grafting (OPCAB) focusing on left ventricular (LV) dyssynchrony. METHODS: A prospective study was performed among 135 patients (age at surgery, mean ± SD: 67.0 ± 8.2 years, 33.3% women) with prior myocardial infarction and moderate IMR undergoing OPCAB from 2008 to 2015. Preoperative and follow-up clinical and echocardiographic parameters were analysed, focusing on LV global/regional dyssynchrony...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29444222/extracorporeal-membrane-oxygenation-as-a-bridge-to-lung-transplantation-may-not-impact-overall-mortality-risk-after-transplantation-results-from-a-7-year-single-centre-experience
#2
Fabio Ius, Ruslan Natanov, Jawad Salman, Christian Kuehn, Wiebke Sommer, Murat Avsar, Thierry Siemeni, Dmitry Bobylev, Reza Poyanmehr, Dietmar Boethig, Joerg Optenhoefel, Nicolaus Schwerk, Axel Haverich, Gregor Warnecke, Igor Tudorache
OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) has an important role in bridging patients to lung transplantation. In this study, we present our experience with pretransplant ECMO during the last 7 years and investigate its impact on graft outcomes. METHODS: Records of all lung-transplanted patients at our institution between January 2010 and April 2017 were retrospectively reviewed. Graft survival was compared between patients who required pretransplant ECMO (pre-Tx ECMO+) and patients who did not (pre-Tx ECMO-)...
February 12, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29442974/vinyl-functionalized-porous-silica-nanospheres-prepared-by-poly-1-vinyl-2-pyrrolidone-grafted-surface-protected-selective-etching-strategy
#3
Jie Li, Jia Zhang, Lianxi Chen, Yu Wang, Zhenhui Liu
A new effective surface poly(1-vinyl-2-pyrrolidone) (PVP) grafted layer protected selective etching strategy has been used for preparing vinyl functionalized porous silica nanospheres (V-PSNSs). The main reaction mechanism was relied on the vinyl groups distributed on the surface of outer vinyl silica nanospheres (V-SiO2) which can be polymerized with another vinyl monomer, such as 1-vinyl-2-pyrrolidone (VP), in the presence of initiator. It was observed from the research results that only grafting PVP on the surface of outer vinyl silica nanospheres (V-SiO2) can V-PSNSs be obtained, because grafting PVP was able to protect outer V-SiO2 from being etched prior to inner pure silica (sSiO2)...
April 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29440793/use-of-an-amniotic-membrane-as-a-novel-barrier-in-a-tooth-with-a-questionable-prognosis
#4
Kanakamedala Anil Kumar, Muppalla Chakravarthy, Shalini Selvarajan, Theyagarajan Ramakrishnan, Geetha Ari
The chief goal of combination therapy using guided tissue regeneration along with bone grafts is to optimally and predictably regenerate the periodontal attachment apparatus. The evolution of regenerative therapy along with careful patient selection and treatment planning can have positive results even in cases which are not ideal. The present case report describes a tooth with a questionable prognosis treated successively by endodontic then periodontal therapy using an amniotic membrane along with a bone graft to treat an intrabony defect...
May 2017: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/29438212/maxillo-mandibular-reconstruction-in-pediatric-patients-how-to-do-it
#5
Valentino Valentini, Luigi Califano, Andrea Cassoni, Della Monaca Marco, Ingrid Raponi, Paolo Priore, Maria Teresa Fadda, Giovanni Dell'Aversana Orabona, Valentina Terenzi
Maxillo-mandibular reconstruction in pediatric patients involves particular functional and cosmetic implications. Attention is required for the craniofacial growth over time, involvement of the permanent dentition, facial symmetry, and donor site morbidity. Our aim is to identify the best reconstructive options for maxilla-mandibular defects in children (<18 years) based on our experience with 25 pediatric patients. We believe that reconstruction has to be performed at the same time as resection in pediatric patients...
February 12, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29433988/effectiveness-and-harms-of-using-kidneys-with-small-renal-tumors-from-deceased-or-living-donors-as-a-source-of-renal-transplantation-a-systematic-review
#6
REVIEW
Vital Hevia, Rhana Hassan Zakri, Claire Fraser Taylor, Harman Maxim Bruins, Romain Boissier, Enrique Lledo, Heinz Regele, Klemens Budde, Arnaldo Figueiredo, Alberto Breda, Cathy Yuhong Yuan, Jonathon Olsburgh
CONTEXT: Kidney transplantation is the best treatment for patients with end-stage renal disease. Incidence of small renal masses (SRMs), which most frequently are renal cell carcinomas (RCCs), is highest in patients aged >60 yr. The increasing age of donors can lead to the diagnosis of a higher number of SRMs when assessing the patient for transplantation, and so can theoretically decrease the number of kidneys suitable for transplantation. Aiming to increase the pool of kidneys suitable for transplantation, a number of studies have reported their experience using kidneys with SRMs for transplantation...
February 9, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29432889/best-medical-treatment-and-selective-stent-graft-repair-for-acute-type-b-aortic-intramural-hematoma
#7
Gabriele Piffaretti, Chiara Lomazzi, Filippo Benedetto, Narayana Pipitò, Patrizio Castelli, Santi Trimarchi, Walter Dorigo, Matteo Tozzi
OBJECTIVES: To describe our experience with the management and the results of stent-graft (SG) repair of acute type B aortic intramural hematoma (B-IMH). METHODS: Between January 2005 and July 2016, we identified 41 B-IMHs. Major end-points were early and long-term survival, aortic remodeling, freedom from aortic-related mortality (ARM), and freedom from reintervention. RESULTS: Thirty-one (76%) patients eventually underwent SG repair: 16 (52%) cases in the acute phase, and 6 (19%) in the subacute (14-30 days) phase...
February 9, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29432654/eccrine-sweat-glands-associate-with-the-human-hair-follicle-within-a-defined-compartment-of-dermal-white-adipose-tissue
#8
E Poblet, F Jimenez-Acosta, E Escario-Travesedo, J A Hardman, I Hernández-Hernández, J L Agudo-Mena, J J Cabrera-Galvan, C Nicu, R Paus
BACKGROUND: Eccrine sweat glands (ESGs) are critical for thermoregulation and involved in wound healing. ESGs have traditionally been considered as separate skin appendages without connection to the pilosebaceous unit (PSU). However, recent preliminary evidence has encouraged the hypothesis that PSU and ESG are more interconnected than previously thought. OBJECTIVE: To reevaluate the morphology of human skin adnexa with an integrated 3D perspective in order to explore the possible interconnections that the PSU and the ESG may form...
February 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29431621/haploidentical-hsct-for-hemoglobinopathies-improved-outcomes-with-tcr%C3%AE-%C3%AE-cd19-depleted-grafts
#9
Javid Gaziev, Antonella Isgrò, Pietro Sodani, Katia Paciaroni, Gioia De Angelis, Marco Marziali, Michela Ribersani, Cecilia Alfieri, Alessandro Lanti, Tiziana Galluccio, Gaspare Adorno, Marco Andreani
We examined outcomes of haploidentical hematopoietic cell transplantation (haplo-HCT) using T-cell receptor αβ + (TCRαβ + )/CD19 + -depleted grafts (TCR group, 14 patients) in children with hemoglobinopathies. Patients received a preparative regimen consisting of busulfan, thiotepa, cyclophosphamide, and antithymocyte globulin preceded by fludarabine, hydroxyurea, and azathioprine. The median follow-up among surviving patients was 3.9 years. The 5-year probabilities of overall survival (OS) and disease-free survival (DFS) were 84% and 69%, respectively...
February 13, 2018: Blood Advances
https://www.readbyqxmd.com/read/29430887/results-of-hybrid-procedures-for-treatment-of-aortoiliac-trans-atlantic-inter-society-consensus-ii-d-lesions-with-self-expanding-covered-heparin-bonded-stent-grafts
#10
Christian Uhl, Thomas Betz, Barbara Weiss, Ingolf Töpel, Markus Steinbauer
INTRODUCTION: According to the guidelines aortoiliac TASC D lesions should be treated by bypass. The purpose of this study was to examine the results of hybrid procedures with the use of a self-expanding covered heparin-bonded stent graft (Viabahn) in patients with extensive aorto-iliac lesions who were not considered to be suitable for open aorto-iliac surgery. METHODS: All patients who received a hybrid procedure in combination with a Viabahn stent in our clinic to treat aortoiliac lesions between October 2011 and April 2017 were included in this retrospective analysis...
February 8, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29430883/models-to-predict-length-of-stay-in-the-intensive-care-unit-after-coronary-artery-bypass-grafting-a-systematic-review
#11
Alireza Atashi, Ilona W Verburg, Hesam Karim, Mirmohammad Miri, Ameen Abu-Hanna, Evert de Jonge, Nicolette F de Keizer, Saeid Eslami
INTRODUCTION: ICU Length of stay (LoS) prediction models are used to compare different institutions and surgeons on their performance, and is useful as an efficiency indicator for quality control. There is little consensus about which prediction methods are most suitable to predict (ICU) length of stay. The aim of this study is to systematically review models for predicting ICU LoS after coronary artery bypass grafting and to assess the reporting and methodological quality of these models to apply them for benchmarking...
February 8, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29430745/liquid-crystalline-dynamic-networks-doped-with-gold-nanorods-showing-enhanced-photocontrol-of-actuation
#12
Xili Lu, Hu Zhang, Guoxia Fei, Bing Yu, Xia Tong, Hesheng Xia, Yue Zhao
A near-infrared-light (NIR)- and UV-light-responsive polymer nanocomposite is synthesized by doping polymer-grafted gold nanorods into azobenzene liquid-crystalline dynamic networks (AuNR-ALCNs). The effects of the two different photoresponsive mechanisms, i.e., the photochemical reaction of azobenzene and the photothermal effect from the surface plasmon resonance of the AuNRs, are investigated by monitoring both the NIR- and UV-light-induced contraction forces of the oriented AuNR-ALCNs. By taking advantage of the material's easy processability, bilayer-structured actuators can be fabricated to display photocontrollable bending/unbending directions, as well as localized actuations through programmed alignment of azobenzene mesogens in selected regions...
February 12, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29430522/multivalent-polymers-displaying-m2-macrophage-targeting-peptides-improve-target-binding-avidity-and-serum-stability
#13
Chayanon Ngambenjawong, Suzie H Pun
Tumor-associated macrophages (TAMs) display a spectrum of phenotypes ranging from pro-tumoral/anti-inflammatory "M2-like" to anti-tumoral/pro-inflammatory "M1-like" subtypes and, consequently, high intratumoral M2-to-M1 ratios are typically indicative of poor disease prognosis. Cancer immunotherapies that selectively modulate M2-like TAMs, enabling reversal of the M2-to-M1 ratio, represent a promising anti-cancer intervention but are difficult to implement due to the lack of effective targeting systems...
September 11, 2017: ACS Biomaterials Science & Engineering
https://www.readbyqxmd.com/read/29430406/effect-of-remote-ischemic-preconditioning-on-troponin-i-in-cabg
#14
Fatemeh Javaherforoosh Zadeh, Mohsen Moadeli, Mansoor Soltanzadeh, Farahzad Janatmakan
Background: Elective open heart surgery is associated with troponin release in some cases due to myocyte necrosis. Objectives: The aim of this study was to measure cardiac troponin I (cTnI) preoperatively in elective CABG after remote ischemic preconditioning. Methods: Twenty-eight patients were selected for elective CABG. They were randomized to receive remote ischemic preconditioning (induced by three 5-min cycles of inflation with a pneumatic tourniquet and 5-min deflation between inflation episodes as reperfusion)...
August 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29427396/size-selective-purification-of-hepatitis-b-virus-like-particle-in-flow-through-chromatography-types-of-ion-exchange-adsorbent-and-grafted-polymer-architecture
#15
Hon Wei Ng, Micky Fu Xiang Lee, Gek Kee Chua, Bee Koon Gan, Wen Siang Tan, Chien Wei Ooi, Siah Ying Tang, Eng Seng Chan, Beng Ti Tey
Hepatitis B virus-like particles expressed in Escherichia coli were purified using anion exchange adsorbents grafted with polymer poly(oligo(ethylene glycol) methacrylate) in flow-through chromatography mode. The virus-like particles were selectively excluded, while the relatively smaller-sized host cell proteins were absorbed. The exclusion of virus-like particles was governed by the accessibility of binding sites (the size of adsorbents and the charge of grafted dextran chains) as well as the architecture (branch-chain length) of the grafted polymer...
February 9, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29426592/the-modified-arch-landing-areas-nomenclature-malan-improves-prediction-of-stent-graft-displacement-forces-proof-of-concept-by-computational-fluid-dynamics-modelling
#16
Massimiliano M Marrocco-Trischitta, Theodorus M van Bakel, Rodrigo M Romarowski, Hector W de Beaufort, Michele Conti, Joost A van Herwaarden, Frans L Moll, Ferdinando Auricchio, Santi Trimarchi
OBJECTIVE: To assess whether the Modified Arch Landing Areas Nomenclature (MALAN), which merges Ishimaru's map with the Aortic Arch Classification, predicts the magnitude of displacement forces and their orientation in proximal landing zones for TEVAR. METHODS: Computational fluid dynamic (CFD) modelling was employed to prove the hypothesis. Healthy aorta CT angiography scans were selected based on aortic arch geometry to reflect Types I to III arches equally (each n = 5)...
February 6, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29426512/surface-imprinted-polymers-based-on-amino-hyperbranched-magnetic-nanoparticles-for-selective-extraction-and-detection-of-chlorogenic-acid-in-honeysuckle-tea
#17
Yayun Zhao, Yuhai Tang, Jun He, Yuan Xu, Ruixia Gao, Junjie Zhang, Tie Chong, Li Wang, Xiaoshuang Tang
Novel water-compatible magnetic molecularly imprinted polymers were developed. The magnetic core was firstly grafted by methyl acrylate and ethanediamine to increase the number of amino groups, which could immobilize more templates and form high-density recognition sites. Dopamine was adopted as functional monomer and crosslinker to retighten templates and prepare hydrophilic polymers. The characterization, adsorption capability, selectivity, and reusability were investigated in detail. The limit of detection and quantification of the method were 0...
May 1, 2018: Talanta
https://www.readbyqxmd.com/read/29426312/anterior-cruciate-ligament-reconstruction-with-quadriceps-tendon-patellar-bone-allograft-matched-case-control-study
#18
Yoon-Ho Kwak, Sahnghoon Lee, Myung Chul Lee, Hyuk-Soo Han
BACKGROUND: Quadriceps tendon-patellar bone (QTPB) autograft is an excellent graft option with good clinical outcome. Use of QTPB autografts have increased because they minimize donor-site morbidity including anterior knee pain, while providing adequate mechanical strength. Although, there were many clinical results about allografts that used in anterior cruciate ligament (ACL) reconstruction, it have never been reported about the clinical outcome of ACL reconstruction with QTPB allograft...
February 9, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29425771/early-outcomes-with-fast-track-evar-in-teaching-and-nonteaching-hospitals
#19
Hiranya A Rajasinghe, Larry E Miller, Zvonimir Krajcer
PURPOSE: To determine feasibility, safety, and effectiveness of a fast-track endovascular aneurysm repair (EVAR) protocol at teaching and nonteaching hospitals. METHODS: Patients underwent a fast-track EVAR protocol comprised of bilateral percutaneous access using a 14 Fr stent graft, avoidance of general anesthesia and intensive care admission, and next-day discharge. Patients were followed through 1 month post-treatment. Participating hospitals were categorized by teaching status (teaching vs...
February 6, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29424485/sub-epithelial-connective-tissue-graft-for-the-management-of-miller-s-class-i-and-class-ii-isolated-gingival-recession-defect-a-systematic-review-of-the-factors-influencing-the-outcome
#20
REVIEW
Anisha P Yadav, Anita Kulloli, Sharath Shetty, Shruti S Ligade, Santosh S Martande, Meenakshi J Gholkar
The aim of the present systematic review was to analyze the factors that affect the outcome of subepithelial connective tissue graft (SCTG) for managing Miller's class I and class II isolated gingival recession defect. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for systematic reviews were used. Quality assessments of selected articles were performed. Data on root surface condition, recession type defect, flap thickness, different flap designs, different harvesting techniques, presence/absence of the epithelial collar, graft thickness, flap tension, suturing techniques, and smoking-related outcomes on root coverage were assessed...
February 9, 2018: Journal of Investigative and Clinical Dentistry
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