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https://www.readbyqxmd.com/read/29684919/clinical-outcomes-and-complications-after-open-reduction-and-internal-fixation-utilizing-conventional-plates-in-65-distal-radial-and-ulnar-fractures-of-miniature-and-toy-breed-dogs
#1
Takeshi Aikawa, Yuta Miyazaki, Taichi Shimatsu, Kyoko Iizuka, Masaaki Nishimura
OBJECTIVE:  This article aims to evaluate clinical outcomes and complications of distal radial and ulnar fractures in miniature- and toy-breed dogs treated with conventional bone plate fixation. METHODS:  Medical records (2001-2010) of miniature- and toy-breed dogs with distal radial and ulnar fractures repaired with open reduction and internal fixation utilizing conventional plates were reviewed. The inclusion criteria were body weight of <7 kg, fracture located in the distal antebrachium (distal-to-total radial length ratio < 0...
April 23, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29684913/does-trade-liberalization-reduce-child-mortality-in-low-and-middle-income-countries-a-synthetic-control-analysis-of-36-policy-experiments-1963-2005
#2
Pepita Barlow
Scholars have long argued that trade liberalization leads to lower rates of child mortality in developing countries. Yet current scholarship precludes definitive conclusions about the magnitude and direction of this relationship. Here I analyze the impact of trade liberalization on child mortality in 36 low- and middle-income countries, 1963-2005, using the synthetic control method. I test the hypothesis that trade liberalization leads to lower rates of child mortality, examine whether this association varies between countries and over time, and explore the potentially modifying role of democratic politics, historical context, and geographic location on the magnitude and direction of this relationship...
April 6, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29684912/cementum-regeneration-using-stem-cells-in-the-dog-model-a-systematic-review
#3
REVIEW
Jacqueline Crossman, Maryam Elyasi, Tarek El-Bialy, Carlos Flores Mir
OBJECTIVE: Restoring lost tissues of the periodontium, such as cementum, is essential in reducing the risk of tooth loss due to periodontitis and/or severe root resorption. Stem cell therapy is a regenerative strategy in cementum regeneration. This systematic review aimed to analyze the effect of various stem cells and their transplantation method on cementum regeneration in the dog model. METHODS: Electronic databases were searched, in addition to performing hand searches and a gray literature search...
April 3, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29684837/patient-safety-content-and-delivery-in-pre-registration-nursing-curricula-a-national-cross-sectional-survey-study
#4
Kim Usher, Cindy Woods, Jane Conway, Jackie Lea, Vicki Parker, Fiona Barrett, Eilish O'Shea, Debra Jackson
BACKGROUND: Patient safety is a core principle of health professional practice and as such requires significant attention within undergraduate curricula. However, patient safety practice is complex requiring a broad range of skills and behaviours including the application of sound clinical knowledge within a range of health care contexts and cultures. There is very little research that explores how this is taught within Australian nursing curricula. OBJECTIVES: To examine how Australian nursing curricula address patient safety; identify where and how patient safety learning occurs; and describe who is responsible for facilitating this learning...
April 17, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29684830/perineal-injury-associated-with-hands-on-hands-poised-and-directed-undirected-pushing-a-retrospective-cross-sectional-study-of-non-operative-vaginal-births-2011-2016
#5
Nigel Lee, Meaghan Firmin, Yu Gao, Sue Kildea
BACKGROUND: Clinicians hand position and advised pushing techniques may impact on rates of perineal injury. OBJECTIVE: To assess the association of four techniques used in management of second stage with risk of moderate and severe perineal injury. DESIGN: Retrospective cross-sectional study. SETTING: A metropolitan maternity hospital and a private maternity hospital in Brisbane, Australia. PARTICIPANTS: Term women with singleton, cephalic presentation experiencing a non-operative vaginal birth from January 2011 to December 2016...
April 5, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29684747/the-possible-dna-damage-induced-by-environmental-organic-compounds-the-case-of-nonylphenol
#6
REVIEW
Zahra Noorimotlagh, Seyyed Abbas Mirzaee, Mehdi Ahmadi, Neemat Jaafarzadeh, Fakher Rahim
Human impact on the environment leads to the release of many pollutants that produce artificial compounds, which can have harmful effects on the body's endocrine system; these are known as endocrine disruptors (EDs). Nonylphenol (NP) is a chemical compound with a nonyl group that is attached to a phenol ring. NP-induced H2 AX is a sensitive genotoxic biomarker for detecting possible DNA damage; it also causes male infertility and carcinogenesis. We attempt to comprehensively review all the available evidence about the different ways with descriptive mechanisms for explaining the possible DNA damage that is induced by NP...
April 20, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29684391/a-randomized-control-trial-of-preoperative-prophylactic-antibiotics-prior-to-percutaneous-nephrolithotomy-in-low-infectious-risk-population-a-report-from-the-edge-consortium
#7
Ben H Chew, Nicole L Miller, Joel E Abbott, Dirk Lange, Mitchell R Humphreys, Vernon M Pais, Manoj Monga, Amy E Krambeck, Roger L Sur
INTRODUCTION: Single institution studies suggest a benefit of a week of preoperative antibiotics prior to percutaneous nephrolithotomy (PCNL). These studies are limited by lower quality methodology such as the inclusion of heterogeneous populations or the use of non-standard definitions of sepsis. The American Urological Association (AUA) Best Practice Statement recommends <24 hours of IV antibiotics, but no other data exist about the duration/benefit of preoperative antibiotics. We sought to perform a rigorous (using CONSORT guidelines), multi-institutional trial to assess preoperative antibiotics in PCNL patients at low risk of developing infections...
April 20, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29684338/plasma-cell-myeloma-with-auer-rode-like-inclusions
#8
Nour AlMozain, Tarek Owaidah
No abstract text is available yet for this article.
April 17, 2018: Hematology/oncology and Stem Cell Therapy
https://www.readbyqxmd.com/read/29684327/do-health-promotion-messages-integrate-unintended-pregnancy-and-sti-prevention-a-content-analysis-of-online-information-for-adolescents-and-young-adults
#9
Riley J Steiner, Catherine N Rasberry, Jessica M Sales, Laura M Gaydos, Karen Pazol, Michael Kramer, Andrea Swartzendruber
OBJECTIVE: Recently there have been calls to strengthen integration of unintended pregnancy and sexually transmitted infection (STI) prevention messages, spurred by increasing use of long-acting reversible contraception. To assess the extent to which public health/clinical messages about unintended pregnancy prevention also address STI prevention, we conducted a content analysis of web-based health promotion information for young people. STUDY DESIGN: Websites identified through a systematic Google search were eligible for inclusion if they were operated by a United States-based organization with a mission related to public health/clinical services and the URL included: 1) original content; 2) about sexual and reproductive health; 3) explicitly for adolescents and/or young adults...
April 20, 2018: Contraception
https://www.readbyqxmd.com/read/29684313/breathing-and-coding-a-bit-easier-changes-to-international-classification-of-disease-coding-for-pulmonary-hypertension
#10
REVIEW
Stephen C Mathai, Sherin Mathew
International Classification of Disease (ICD) coding system is broadly utilized by healthcare providers, hospitals, healthcare payers, and governments to track health trends and statistics at the global, national, and local levels and to provide a reimbursement framework for medical care based upon diagnosis and severity of illness. The current iteration of the ICD system, ICD-10, was implemented in 2015. While many changes to the prior ICD-9 system were included in the ICD-10 system, the newer revision failed to adequately reflect advances in the clinical classification of certain diseases such as pulmonary hypertension (PH)...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29684288/endobronchial-ultrasound-for-nodal-staging-of-non-small-cell-lung-cancer-patients-with-radiologically-normal-mediastinum-a-meta-analysis
#11
Hazem El-Osta, Pushan Jani, Ali Mansour, Philip Rascoe, Syed Jafri
RATIONALE: An accurate assessment of the mediastinal lymph nodes status is essential in the staging and treatment planning of potentially resectable non-small cell lung cancer (NSCLC). OBJECTIVES: We performed this meta-analysis to evaluate the role of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in detecting occult mediastinal disease in NSCLC with no radiologic mediastinal involvement. METHODS: The PubMed, Embase, and Cochrane libraries were searched for studies describing the role of EBUS-TBNA in lung cancer patients with radiologically negative mediastinum...
April 23, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29684250/electronic-medication-administration-records-in-long-term-care-facilities-a-scoping-review
#12
REVIEW
Andrew E C Fuller, Lisa M Guirguis, Cheryl A Sadowski, Mark J Makowsky
OBJECTIVES: To map the extent, range, and nature of research on the effectiveness, level of use, and perceptions about electronic medication administration records (eMARs) in long-term care facilities (LTCFs) and identify gaps in current knowledge and priority areas for future research. DESIGN: Scoping review of quantitative and qualitative literature. SETTING: Literature review. PARTICIPANTS: Original research relating to eMAR in LTCF was eligible for inclusion...
April 23, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29684249/standard-head-down-tilt-versus-modified-without-head-down-tilt-postural-drainage-in-infants-and-young-children-with-cystic-fibrosis
#13
REVIEW
Diana A Freitas, Gabriela Ss Chaves, Thayla A Santino, Cibele Td Ribeiro, Fernando Al Dias, Ricardo O Guerra, Karla Mpp Mendonça
BACKGROUND: Postural drainage is used primarily in infants with cystic fibrosis from diagnosis up to the moment when they are mature enough to actively participate in self-administered treatments. However, there is a risk of gastroesophageal reflux associated with this technique.This is an update of a review published in 2015. OBJECTIVES: To compare the effects of standard postural drainage (15º to 45º head-down tilt) with modified postural drainage (15º to 30º head-up tilt) with regard to gastroesophageal reflux in infants and young children up to six years old with cystic fibrosis in terms of safety and efficacy...
March 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29684200/ultrasound-for-assessing-disease-activity-in-ibd-patients-a-systematic-review-of-activity-scores
#14
S Bots, K Nylund, M Löwenberg, K Gecse, O H Gilja, G D'Haens
Background and aims: Ultrasound (US) indices for assessing disease activity in IBD patients have never been critically reviewed. We aimed to systematically review the quality and reliability of available ultrasound (US) indices compared with reference standards for grading disease activity in IBD patients. Methods: Pubmed, Embase and Medline were searched from 1990 until June 2017. Relevant publications were identified through full text review after initial screening by 2 investigators...
April 19, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29684187/non-invasive-epicardial-and-endocardial-electrocardiographic-imaging-for-scar-related-ventricular-tachycardia
#15
Linwei Wang, Omar A Gharbia, Saman Nazarian, B Milan Horácek, John L Sapp
Aims: Contact mapping is currently used to guide catheter ablation of scar-related ventricular tachycardia (VT) but usually provides incomplete assessment of 3D re-entry circuits and their arrhythmogenic substrates. This study investigates the feasibility of non-invasive electrocardiographic imaging (ECGi) in mapping scar substrates and re-entry circuits throughout the epicardium and endocardium. Methods and results: Four patients undergoing endocardial and epicardial mapping and ablation of scar-related VT had computed tomography scans and a 120-lead electrocardiograms, which were used to compute patient-specific ventricular epicardial and endocardial unipolar electrograms (CEGMs)...
April 18, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29684153/determination-of-cytoplasmic-optineurin-foci-sizes-using-image-correlation-spectroscopy
#16
Akira Kitamura, Hiroki Shimizu, Masataka Kinjo
Optineurin (OPTN) plays an important role in membrane trafficking processes such as exocytosis and autophagy. The sizes and rate of formation of accumulated structures comprising OPTN, such as foci or inclusion bodies (IBs), are often disrupted by amyotrophic lateral sclerosis (ALS) and glaucoma-associated mutants of OPTN. Therefore, methods for the quantitative measurement of the size of the accumulated structure are necessary. Here, we show that, using spatial image correlation spectroscopy (ICS), the average diameter of accumulated structures of the wild type and disease-associated mutants in living cells may be easily determined...
April 19, 2018: Journal of Biochemistry
https://www.readbyqxmd.com/read/29684151/a-new-framework-for-patient-engagement-in-cancer-clinical-trials-cooperative-group-studies
#17
Patricia A Deverka, Rick Bangs, Karma Kreizenbeck, Deborah M Delaney, Dawn L Hershman, Charles D Blanke, Scott D Ramsey
For the past two decades, the National Cancer Institute (NCI) has supported the involvement of patient advocates in both internal advisory activities and funded research projects to provide a patient perspective. Implementation of the inclusion of patient advocates has varied considerably, with inconsistent involvement of patient advocates in key phases of research such as concept development. Despite this, there is agreement that patient advocates have improved the patient focus of many cancer research studies...
April 18, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29684065/biochemical-properties-of-l-arabinose-isomerase-from-clostridium-hylemonae-to-produce-d-tagatose-as-a-functional-sweetener
#18
Tien-Kieu Nguyen, Moon-Gi Hong, Pahn-Shick Chang, Byung-Hoo Lee, Sang-Ho Yoo
d-Tagatose has gained substantial interest due to its potential functionalities as a sucrose substitute. In this study, the gene araA, encoding l-arabinose isomerase (l-AI) from Clostridium hylemonae (DSM 15053), was cloned and expressed in Escherichia coli BL21 (DE3). This gene consists of 1,506 nucleotides and encodes a protein of 501 amino acid residues with a calculated molecular mass of 56,554 Da. Since l-AI was expressed as an intracellular inclusion body, this enzyme was solubilized with guanidine hydrochloride, refolded, and activated with a descending concentration gradient of urea...
2018: PloS One
https://www.readbyqxmd.com/read/29684024/crystallized-and-fluid-intelligence-of-university-students-with-intellectual-disability-who-are-fully-integrated-versus-those-who-studied-in-adapted-enrichment-courses
#19
Hefziba Lifshitz, Jay Verkuilen, Shlomit Shnitzer-Meirovich, Carmit Altman
BACKGROUND: Inclusion of people with intellectual disability (ID) in higher postsecondary academic education is on the rise. However, there are no scientific criteria for determining the eligibility for full inclusion of students with ID in university courses. This study focuses on two models of academic inclusion for students with ID: (a) separate adapted enrichment model: students with ID study in separate enrichment courses adapted to their level; (b) full inclusion model: students with ID are included in undergraduate courses, receive academic credits and are expected to accumulate the amount of credits for a B...
2018: PloS One
https://www.readbyqxmd.com/read/29684022/open-label-comparative-trial-of-mono-versus-dual-antibiotic-therapy-for-typhoid-fever-in-adults
#20
Niv Zmora, Sudeep Shrestha, Ami Neuberger, Yael Paran, Rajendra Tamrakar, Ashish Shrestha, Surendra K Madhup, T R S Bedi, Rajendra Koju, Eli Schwartz
BACKGROUND: Emerging resistance to antibiotics renders therapy of Typhoid Fever (TF) increasingly challenging. The current single-drug regimens exhibit prolonged fever clearance time (FCT), imposing a great burden on both patients and health systems, and potentially contributing to the development of antibiotic resistance and the chronic carriage of the pathogens. The aim of our study was to assess the efficacy of combining third-generation cephalosporin therapy with azithromycin on the outcomes of TF in patients living in an endemic region...
April 2018: PLoS Neglected Tropical Diseases
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