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https://www.readbyqxmd.com/read/28933833/total-synthesis-of-nahuoic-acid-ci-bii
#1
Qi Liu, Yifan Deng, Amos B Smith
A convergent total synthesis of (-)-nahuoic acid Ci(Bii) (3), a novel cis-decalin polyketide, has been achieved. Key synthetic transformations include Type II Anion Relay Chemistry (ARC) to construct the polyol chain, a Ti-catalyzed asymmetric Diels-Alder reaction to generate the cis-decalin skeleton, and a late-stage large fragment union exploiting a Micalizio alkoxide-directed alkyne-alkene coupling tactic.
September 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28933715/rating-of-perceived-exertion-for-quantification-of-training-and-combat-loads-during-combat-sport-specific-activities-a-short-review
#2
Maamer Slimani, Philip Davis, Emerson Franchini, Wassim Moalla
Slimani, M, Davis, P, Franchini, E, and Moalla, W. Rating of perceived exertion for quantification of training and combat loads during combat sport-specific activities: a short review. J Strength Cond Res 31(10): 2889-2902, 2017-The aim of this short review was to summarize data pertaining to the rating of perceived exertion (RPE) methods (RPE value and session-RPE) during combat sport-specific activities (i.e., competition and training) based on many factors, including contest type (i.e., official vs. simulated vs...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28933552/a-metal-and-solvent-free-approach-to-diversely-substituted-picolinates-via-domino-reaction-of-cyclic-sulfamidate-imines-with-%C3%AE-%C3%AE-unsaturated-%C3%AE-ketocarbonyls
#3
Soumen Biswas, Debashis Majee, Soumitra Guin, Sampak Samanta
An efficient, solvent-free and eco-friendly domino reaction of 5/6-membered cyclic sulfamidate imines with a variety of β,γ-unsaturated α-ketocarbonyls in a neat condition under MW irradiation promoted by DABCO as a solid organobase has been developed for the rapid construction of a novel class of densely functionalized picolinates. This interesting metal-solvent-free tactic allows allows a wide range of useful functionalities on the aryl rings and delivers good to excellent yields of the aforesaid aza-heterocycles within short span of times (20-40 min)...
September 21, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28931161/probing-behavior-of-dichelops-furcatus-f-heteroptera-pentatomidae-on-wheat-plants-characterized-by-electropenetrography-epg-and-histological-studies
#4
Tiago Lucini, Antônio Ricardo Panizzi
The stink bug Dichelops furcatus (F.) (Heteroptera: Pentatomidae) has increased in abundance in recent years on the wheat, Triticum aestivum L., crop cultivated in the southern region of Brazil. To investigate the probing (stylet penetration) behaviors and nonprobing behaviors of D. furcatus on wheat plants, the electrical penetration graph or electropenetrography (EPG) technique was applied. Nine EPG waveforms (types/subtypes) were identified and described on stem and on ear head of wheat plants, as follows: Z, Np, Df1a, Df1b, Df2, Df3a, Df3b, Df4a, and Df4b...
January 1, 2017: Journal of Insect Science
https://www.readbyqxmd.com/read/28930639/50-years-of-research-in-ards-tidal-volume-selection-in-the-acute-respiratory-distress-syndrome
#5
Sarina K Sahetya, Jordi Mancebo, Roy G Brower
Mechanical ventilation (MV) is critical in the management of many patients with the acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate tidal volume is an essential part of a lung-protective MV strategy. Since the publication of a large randomized clinical trial demonstrating the benefit of lower tidal volumes, the use of tidal volumes of 6 mL/kg predicted body weight (PBW, based on sex and height) has been recommended in clinical practice guidelines...
September 20, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28929847/healthcare-the-speed-of-thought-a-digital-world-needs-successful-transformative-leaders
#6
Ken Tremblay
In the wake of transformational change powered by the digital era, resultant leadership challenges and strategies essential for successful change, both tactical and cultural, are linked to defined capabilities within the Systems Transformation domain of the LEADS in a Caring Environment framework. Honed from experience, specific softer leadership behaviours supporting system transformation are both described and reinforced. Further, a matrix combining the LEADS framework capabilities with these more specific behaviours is offered as a planning tool that leaders may reflect upon and map out key activities associated with their sponsorship of significant change...
September 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28925415/quality-requirements-for-electronic-health-record-systems-a-japanese-german-information-management-perspective
#7
Alfred Winter, Katsuhiko Takabayashi, Franziska Jahn, Eizen Kimura, Rolf Engelbrecht, Reinhold Haux, Masayuki Honda, Ursula H Hübner, Sozo Inoue, Christian D Kohl, Takehiro Matsumoto, Yasushi Matsumura, Kengo Miyo, Naoki Nakashima, Hans-Ulrich Prokosch, Martin Staemmler
BACKGROUND: For more than 30 years, there has been close cooperation between Japanese and German scientists with regard to information systems in health care. Collaboration has been formalized by an agreement between the respective scientific associations. Following this agreement, two joint workshops took place to explore the similarities and differences of electronic health record systems (EHRS) against the background of the two national healthcare systems that share many commonalities...
August 7, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28925292/using-a-media-campaign-to-increase-engagement-with-a-mobile-based-youth-smoking-cessation-program
#8
Amy Sanders, Cendrine Robinson, Shani C Taylor, Samantha D Post, Jeffrey Goldfarb, Rui Shi, Yvonne M Hunt, Erik M Augustson
PURPOSE: To describe the impact of the National Cancer Institute's promotion of its youth smoking cessation program, Smokefree Teen (SFT). DESIGN: We provide a description of campaign strategies and outcomes as a means to engage a teen audience in cessation resources using a cost-effective approach. SETTING: The campaign occurred nationally, using traditional (TV and radio), online, and social media outreach. PARTICIPANTS: Ads targeted adolescent smokers (aged 14-17)...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28922069/glutamatergic-agents-in-the-treatment-of-compulsivity-and-impulsivity-in-child-and-adolescent-psychiatry-a-systematic-review-of-the-literature
#9
Konstantin Mechler, Alexander Häge, Nina Schweinfurth, Jeffrey C Glennon, Rick M Dijkhuizen, Declan Murphy, Sarah Durston, Steven Williams, Jan K Buitelaar, Tobias Banaschewski, Ralf W Dittmann, The Tactics Consortium
OBJECTIVE: Research has implicated glutamatergic projections between the various frontal subregions in the pathogenesis of compulsivity and impulsivity. Reducing striatal glutamate release, or antagonising the action of glutamate at its receptors, may therefore represent viable treatment strategies. Several glutamatergic agents with regulatory approval for other indications are available and may be of potential benefit in the treatment of compulsivity/impulsivity in psychiatric disorders in paediatric patients...
September 18, 2017: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/28921610/validation-and-adaptation-of-the-danger-assessment-5-da-5-a-brief-intimate-partner-violence-risk-assessment
#10
Jill Theresa Messing, Jacquelyn C Campbell, Carolyn Snider
AIMS: To assess the predictive validity of the DA-5 with the addition of a strangulation item in evaluating the risk of an intimate partner violence (IPV) victim being nearly killed by an intimate partner. BACKGROUND: The DA-5 was developed as a short form of the Danger Assessment for use in healthcare settings, including emergency and urgent care settings. Analyzing data from a sample of IPV survivors who had called the police for domestic violence, the DA-5 was tested with and without an item on strangulation, a potentially fatal and medically damaging IPV tactic used commonly by dangerous abusers...
September 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28915991/adolescent-and-parental-reactions-to-puberty-in-nigeria-and-kenya-a-cross-cultural-and-intergenerational-comparison
#11
Bamidele M Bello, Adesegun O Fatusi, Oluwatomi E Adepoju, Beatrice W Maina, Caroline W Kabiru, Marni Sommer, Kristin Mmari
PURPOSE: This qualitative study assesses the cross-cultural and intergenerational reactions of young adolescents and parents to puberty in Ile-Ife, Nigeria, and Nairobi, Kenya. METHODS: Sixty-six boys and girls (aged 11-13 years) and their parents participated in narrative interviews conducted in English or local languages in two urban poor settings in Ile-Ife and Nairobi. All interviews were recorded, transcribed, translated, and uploaded into Atlas.ti software for coding and analysis...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28915244/metacognitive-monitoring-and-control-in-visual-change-detection-implications-for-situation-awareness-and-cognitive-control
#12
Ken I McAnally, Adam P Morris, Christopher Best
Metacognitive monitoring and control of situation awareness (SA) are important for a range of safety-critical roles (e.g., air traffic control, military command and control). We examined the factors affecting these processes using a visual change detection task that included representative tactical displays. SA was assessed by asking novice observers to detect changes to a tactical display. Metacognitive monitoring was assessed by asking observers to estimate the probability that they would correctly detect a change, either after study of the display and before the change (judgement of learning; JOL) or after the change and detection response (judgement of performance; JOP)...
2017: PloS One
https://www.readbyqxmd.com/read/28914832/-enteroenterostomy-in-surgical-treatment-of-malignant-colonic-obstruction
#13
V N Ektov
AIM: To consider surgical tactics and to study the immediate results of primary enteroenterostomy in surgical treatment of malignant colonic obstruction. MATERIAL AND METHODS: Radical surgery was performed in 170 (63.9%) out of 266 patients with malignant obstructive colonic obstruction. Colonic resection followed by anastomosis was performed in 68 patients. Conventional hemicolectomy (9 patients) and various original techniques of Y-shaped ileotransversanastomoses (27 patients) were used for right-sided tumor process...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28913925/a-cascade-of-destabilizations-combining-wolbachia-and-allee-effects-to-eradicate-insect-pests
#14
Julie C Blackwood, Roger Vargas, Xavier Fauvergue
1.The management of insect pests has long been dominated by the use of chemical insecticides, with the aim of instantaneously killing enough individuals to limit their damage. To minimize unwanted consequences, environmentally friendly approaches have been proposed that utilize biological control and take advantage of intrinsic demographic processes to reduce pest populations. 2.We address the feasibility of a novel pest management strategy based on the release of insects infected with Wolbachia, which causes cytoplasmic incompatibilities in its host population, into a population with a pre-existing Allee effect...
September 15, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28913520/evidential-value-of-polymeric-materials-chemometric-tactics-for-spectral-data-compression-combined-with-likelihood-ratio-approach
#15
A Menżyk, A Martyna, G Zadora
Polymers have become a ubiquitous element of our culture. Therefore, these materials may play an important role in forensic investigations, serving as mute witnesses of occurrences such as car accidents. In this study, the possibilities provided by the likelihood ratio (LR) approach to estimate the evidential value of observed similarities and differences, and to discriminate among NIR spectral data originating from polypropylene automotive parts and household items, were investigated. Since the construction of LR models requires the introduction of only a few variables, the main objective was to reduce the dimensionality of registered spectra, which are characterised by over a thousand variables...
September 15, 2017: Analyst
https://www.readbyqxmd.com/read/28910488/tactical-combat-casualty-care-updates
#16
Harold R Montgomery, Frank K Butler
No abstract text is available yet for this article.
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28910475/chest-seal-placement-for-penetrating-chest-wounds-by-prehospital-ground-forces-in-afghanistan
#17
Steven G Schauer, Michael D April, Jason F Naylor, Erica M Simon, Andrew D Fisher, Cord W Cunningham, Daniel M Morissette, Jessie Renee D Fernandez, Kathy L Ryan
BACKGROUND: Thoracic trauma represents 5% of all battlefield injuries. Communicating pneumothoraces resulting in tension physiology remain an important etiology of prehospital mortality. In addressing penetrating chest trauma, current Tactical Combat Casualty Care (TCCC) guidelines advocate the immediate placement of a vented chest seal device. Although the Committee on TCCC (CoTCCC) has approved numerous chest seal devices for battlefield use, few data exist regarding their use in a combat zone setting...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28910473/optimization-of-simulation-and-moulage-in-military-related-medical-training
#18
Christopher Petersen, Stephen C Rush, Isabelle Gallo, Bryan Dalere, Brian Staak, Litt Moore, Win Kerr, Matthew Chandler, Will Smith
Preparation of Special Operations Forces (SOF) Medics as first responders for the battle space and austere environments is critical to optimize survival and quality of life for our Operators who may sustain serious and complex wounding patterns and illnesses. In the absence of constant clinical exposure for these medics, it is necessary to maximize all available training opportunities. The incorporation of scenario-based training helps weave together teamwork and the ability to practice treatment protocols in a tactical, controlled training environment to reproduce, to some degree, the environment in and stressors under which care will need to be delivered...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28910472/a-descriptive-analysis-of-occupational-fatalities-due-to-felonious-assault-among-u-s-law-enforcement-officers-during-tactical-incidents-1996-2014
#19
Moriah S Thompson, Tyler M Hartman, Matthew D Sztajnkrycer
INTRODUCTION: Little is known about occupational fatalities among tactical officers. A greater understanding of such injuries is needed to improve officer safety. The purpose of this study was to provide a descriptive analysis of line-of-duty deaths secondary to felonious assault during tactical incidents. METHODS: Retrospective analysis was performed of open-source de-identified Federal Bureau of Investigation Uniform Crime Reporting Law Enforcement Officers Killed and Assaulted (LEOKA) data inclusive of the years 1996-2014...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28910471/evaluation-of-xstat%C3%A2-and-quickclot%C3%A2-combat-gauze%C3%A2-in-a-swine-model-of-lethal-junctional-hemorrhage-in-coagulopathic-swine
#20
Jennifer M Cox, Jason M Rall
BACKGROUND: Hemorrhage is associated with most potentially survivable deaths on the battlefield. Effective and field-tested products are lacking to treat junctional and noncompressible injuries. XSTAT® is a newly developed, U.S. Food and Drug Administration-approved product designed to treat junctional hemorrhage. The Committee on Tactical Combat Casualty Care has recently approved the product for use as part of its treatment guidelines, but data are lacking to assess its efficacy in different wounding patterns and physiologic states...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
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