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https://www.readbyqxmd.com/read/28097982/diversion-tactics-won-t-fix-a-system-at-breaking-point
#1
(no author information available yet)
Winter is always a challenge for the NHS, with the bad weather arriving just as hospitals and community service providers are running out of money at the end of the financial year.
January 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28095679/non-naturally-occurring-small-molecule-microtubule-stabilizing-agents-a-potential-tactic-for-cns-directed-therapies
#2
Carlo Ballatore, Kurt R Brunden, John Q Trojanowski, Virginia M-Y Lee, Amos B Smith
Several independent studies indicate that microtubule (MT)-stabilizing agents hold considerable promise as candidate therapeutics for a wide spectrum of conditions of the central nervous system (CNS), from brain tumors to spinal cord injury, as well as a number of neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, Parkinson's disease, and amyotrophic lateral sclerosis. Although the identification and development of candidate compounds for CNS-directed MT-stabilizing therapies has been a challenge in drug discovery for many years, a growing number of molecules have now been identified that exhibit both MT-stabilizing activity and brain penetration...
January 18, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28095414/mosquito-disseminated-insecticide-for-citywide-vector-control-and-its-potential-to-block-arbovirus-epidemics-entomological-observations-and-modeling-results-from-amazonian-brazil
#3
Fernando Abad-Franch, Elvira Zamora-Perea, Sérgio L B Luz
BACKGROUND: Mosquito-borne viruses threaten public health worldwide. When the ratio of competent vectors to susceptible humans is low enough, the virus's basic reproductive number (R0) falls below 1.0 (each case generating, on average, <1.0 additional case) and the infection fades out from the population. Conventional mosquito control tactics, however, seldom yield R0 < 1.0. A promising alternative uses mosquitoes to disseminate a potent growth-regulator larvicide, pyriproxyfen (PPF), to aquatic larval habitats; this kills most mosquito juveniles and substantially reduces adult mosquito emergence...
January 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28095106/gender-differences-in-static-and-dynamic-postural-stability-of-soldiers-of-the-army-s-101st-airborne-division-air-assault
#4
Timothy C Sell, Mita T Lovalekar, Takashi Nagai, Michael D Wirt, John P Abt, Scott M Lephart
CONTEXT: Postural stability is essential for injury prevention and performance. Differences between genders may affect training focus. OBJECTIVE: To examine static and dynamic postural stability (PS) in male and female Soldiers Design: Descriptive Laboratory Study. SETTING: Biomechanics laboratory. PARTICIPANTS: Twenty-five healthy female Soldiers (26.4 ± 5.3 years) and twenty-five healthy male Soldiers (26.4 ± 4.9) years matched on physical demand rating, and years of service from the Army's 101st Airborne Division (Air Assault)...
January 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28095069/the-evolution-of-champion-cross-country-skier-training-from-lumberjacks-to-professional-athletes
#5
Øyvind Sandbakk
Competitive cross-country (XC) skiing has traditions extending back to the mid-19th century, and was included as a men's event in the first Winter Games in 1924. Since then, tremendous improvements in equipment, track preparation, and knowledge about training have prompted greater increases in XC skiing speeds than in any other Olympic sport. In response, this commentary focuses on how the training of successful XC skiers has evolved, with interviews and training data from surviving Norwegian world and Olympic XC champions as primary sources...
January 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28095025/the-influence-of-personal-protection-equipment-occupant-body-size-and-restraint-system-on-the-frontal-impact-responses-of-hybrid-iii-atds-in-tactical-vehicles
#6
Lauren Wood Zaseck, Nichole Ritchie Orton, Rebekah Gruber, Jonathan Rupp, Risa Scherer, Matthew Reed, Jingwen Hu
OBJECTIVE: Although advanced restraint systems, such as seatbelt pretensioners, and load limiters, can provide improved occupant protection in crashes, such technologies are currently not utilized in military vehicles. The design and use of military vehicles presents unique challenges to occupant safety - including differences in compartment geometry and occupant clothing and gear - that make direct application of optimal civilian restraint systems to military vehicles inappropriate. For military vehicle environments, finite element (FE) modeling can be used to assess various configurations of restraint systems and determine the optimal configuration that minimizes injury risk to the occupant...
January 17, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28093887/collagen-hydrogel-scaffold-promotes-mesenchymal-stem-cell-and-endothelial-cell-coculture-for-bone-tissue-engineering
#7
Bao-Ngoc B Nguyen, Rebecca A Moriarty, Tim Kamalitdinov, Julie M Etheridge, John P Fisher
The generation of functional, vascularized tissues is a key challenge for the field of tissue engineering. Before clinical implantations of such tissue engineered bone constructs can succeed, tactics to promote neovascularization need to be strengthened. We have previously demonstrated that the tubular perfusion system (TPS) bioreactor is an effective culturing method to augment osteogenic differentiation and maintain viability of human mesenchymal stem cells (hMSC). Here, we devised a strategy to address the need for a functional microvasculature by designing an in vitro coculture system that simultaneously cultures osteogenic differentiating hMSCs with endothelial cells (ECs)...
January 17, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28093769/low-migratory-connectivity-is-common-in-long-distance-migrant-birds
#8
Tom Finch, Simon Butler, Aldina Franco, Will Cresswell
1.Estimating how much long-distance migrant populations spread out and mix during the non-breeding season (migratory connectivity) is essential for understanding and predicting population dynamics in the face of global change. 2.We quantify variation in population spread and inter-population mixing in long-distance, terrestrial migrant land-bird populations (712 individuals from 98 populations of 45 species, from tagging studies in the Neotropic and Afro-Palearctic flyways). We evaluate the Mantel test as a metric of migratory connectivity, and explore the extent to which variance in population spread can be explained simply by geography...
January 16, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28091570/increasing-the-potential-for-malaria-elimination-by-targeting-zoophilic-vectors
#9
Jessica L Waite, Sunita Swain, Penelope A Lynch, S K Sharma, Mohammed Asrarul Haque, Jacqui Montgomery, Matthew B Thomas
Countries in the Asia Pacific region aim to eliminate malaria by 2030. A cornerstone of malaria elimination is the effective management of Anopheles mosquito vectors. Current control tools such as insecticide treated nets or indoor residual sprays target mosquitoes in human dwellings. We find in a high transmission region in India, malaria vector populations show a high propensity to feed on livestock (cattle) and rest in outdoor structures such as cattle shelters. We also find evidence for a shift in vector species complex towards increased zoophilic behavior in recent years...
January 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28088552/antipredator-tactics-are-largely-maternally-controlled-in-goitered-gazelle-a-hider-ungulate
#10
David Blank
Predation is usually the primary cause of infant death among ungulate species, with the annual variation in the survival of neonates over their first summer a major factor in the population dynamics of many ungulates. Consequently, the maternal rearing strategy of a species is crucial for its reproductive success. Since the roles mothers and fawns play in the implementation of antipredator strategies in hider species have been poorly understood until now, this paper considers this behavior in the goitered gazelle, which is a typical hider species...
January 11, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28081033/performance-aspects-and-physiological-responses-in-male-amateur-boxing-competitions-a-brief-review
#11
Maamer Slimani, Helmi Chaabène, Philip Davis, Emerson Franchini, Karim Chamari
Boxing is one of the most popular striking combat sports in the world. The aim of this review was to present data concerning performance analysis (time-motion and technical/tactical analysis) and physiological responses (i.e., blood lactate concentration [BLC], heart rate and/or oxygen consumption) during novice and elite male simulated and official amateur boxing competitions in any age category. The present review shows that boxing competition is a high-intensity intermittent striking combat sport. Typically, the activity-to-rest ratio was higher in elite (18:1) than novice (9:1) boxers and significant differences were observed between rounds (1 round=16:1, 2 round=8:1, and 3 round=6:1) in novice boxers...
January 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28079258/combined-effect-of-therapeutic-strategies-for-bleeding-injury-on-early-survival-transfusion-needs-and-correction-of-coagulopathy
#12
K Balvers, S van Dieren, K Baksaas-Aasen, C Gaarder, K Brohi, S Eaglestone, S Stanworth, P I Johansson, S R Ostrowski, J Stensballe, M Maegele, J C Goslings, N P Juffermans
BACKGROUND: The combined effects of balanced transfusion ratios and use of procoagulant and antifibrinolytic therapies on trauma-induced exsanguination are not known. The aim of this study was to investigate the combined effect of transfusion ratios, tranexamic acid and products containing fibrinogen on the outcome of injured patients with bleeding. METHODS: A prospective multicentre observational study was performed in six level 1 trauma centres. Injured patients who received at least 4 units of red blood cells (RBCs) were analysed and divided into groups receiving a low (less than 1 : 1) or high (1 or more : 1) ratio of plasma or platelets to RBCs, and in receipt or not of tranexamic acid or fibrinogen products (fibrinogen concentrates or cryoprecipitate)...
January 12, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28078387/landowners-perspectives-on-coordinated-landscape-level-invasive-species-control-the-role-of-social-and-ecological-context
#13
Rebecca M Niemiec, Roger P Pech, Grant L Norbury, Andrea E Byrom
To achieve biodiversity gains, landowner engagement in coordinated invasive species control programs across private lands is needed. Understanding landowners' perspectives toward such coordinated control efforts is crucial to facilitating engagement. We conducted in person and mail surveys of 68 landowners in and adjacent to the area of a proposed invasive predator control program in New Zealand. We find that, similar to previous studies, landowners consider the potential socioeconomic and ecological benefits of invasive species control and express a strong desire to enhance native biodiversity...
January 11, 2017: Environmental Management
https://www.readbyqxmd.com/read/28077685/working-with-what-you-ve-got-unattractive-males-show-greater-mate-guarding-effort-in-a-duetting-songbird
#14
Jenélle Dowling, Michael S Webster
When mates are limited, individuals should allocate resources to mating tactics that maximize fitness. In species with extra-pair paternity (EPP), males can invest in mate guarding, or, alternatively, in seeking EPP. Males should optimize fitness by adjusting investment according to their attractiveness to females, such that attractive males seek EPP, and unattractive males guard mates. This theory has received little empirical testing, leaving our understanding of the evolution of mating tactics incomplete; it is unclear how a male's relative attractiveness influences his tactics...
January 2017: Biology Letters
https://www.readbyqxmd.com/read/28076535/-femicides-in-ethnic-and-racialized-groups-syntheses
#15
Stela Nazareth Meneghel, Betty Ruth Lozano Lerma
The text entitled "Femicides in ethnic and racialized groups: syntheses" presents some of the discussions that took place during a seminar on this topic in Buenaventura. Buenaventura is the main Colombian port on the Pacific, a region rich in minerals and a corridor for the movement of goods, which makes it a strategic territory and a center for disputes. At the seminar, the social and political determinants of femicide were discussed, understanding it as a tactic of waging war against women. The forum provided a space for academic discussion, but also for grievances over inter-personal violence, the manifestation of feelings and the elaboration of pain and grief through the medium of art...
January 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28074546/-hypoxia-and-cellular-metabolism-in-tumour-pathophysiology
#16
Scott K Parks, Yann Cormerais, Jacques Pouysségur
Cancer cells are optimized for growth and survival via an ability to outcompete normal cells in their microenvironment. Many of these advantageous cellular adaptations are promoted by the pathophysiological hypoxia that arises in solid tumours due to incomplete vascularisation. Tumour cells are thus faced with the challenge of an increased need for nutrients to support the drive for proliferation in the face of a diminished extracellular supply. Among the many modifications occurring in tumour cells, Hypoxia Inducible Factors (HIFs) act as essential drivers of key pro-survival pathways via the promotion of numerous membrane and cytosolic proteins...
January 10, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28072647/tools-for-practical-psychotherapy-a-transtheoretical-collection-or-interventions-which-have-at-least-worked-for-us
#17
Joel Yager, Robert E Feinstein
BACKGROUND AND OBJECTIVES: Regardless of their historical and theoretical roots, strategies, tactics, and techniques used in everyday psychotherapy across diverse theoretical schools contain common factors and methods from other specific psychotherapeutic modalities that contribute substantially to psychotherapy outcomes. Common factors include alliance, empathy, goal consensus/collaboration, positive regard/affirmation, and congruence/genuineness, among others. All therapies also recognize that factors specific to therapists impact treatment...
January 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28068210/how-players-exploit-variability-and-regularity-of-game-actions-in-female-volleyball-teams
#18
Ana Ramos, Patrícia Coutinho, Pedro Silva, Keith Davids, Isabel Mesquita
Variability analysis has been used to understand how competitive constraints shape different behaviours in team sports. In this study, we analysed and compared variability of tactical performance indices in players within complex I at two different competitive levels in volleyball. We also examined whether variability was influenced by set type and period. Eight matches from the 2012 Olympics competition and from the Portuguese national league in the 2014-2015 season were analysed (1496 rallies). Variability of setting conditions, attack zone, attack tempo and block opposition was assessed using Shannon entropy measures...
January 9, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28068161/introduction-to-the-tactical-athlete-special-issue
#19
JoEllen M Sefton, Todd A Burkhardt
No abstract text is available yet for this article.
November 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/28058094/shane-o-mara-s-why-torture-doesn-t-work-the-neuroscience-of-interrogation
#20
Moheb Costandi
Waterboarding, sleep deprivation, and solitary confinement were some of the tactics outlined and authorized in a series of Bush Administration secret legal documents, known as the "torture memos," which were made public in 2009. Shane O'Mara's new book casts morality aside to examine whether torture produces reliable information. He reviews existing research in psychology and neuroscience to highlight the impact of torture methods on brain function.
November 2016: Cerebrum: the Dana Forum on Brain Science
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