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https://www.readbyqxmd.com/read/28528727/sexual-inactivity-in-partnered-female-cancer-survivors
#1
Jennifer L Marino, Christobel M Saunders, Martha Hickey
OBJECTIVE: To measure sexual activity in a clinic population of partnered female cancer survivors, and to better understand reasons for sexual inactivity in this population. MATERIALS AND METHODS: Partnered peri- or post-menopausal cancer survivors seen at a specialty clinic for menopause symptoms after cancer completed Fallowfield's Sexual Activity Questionnaire, quality of life measures (the Functional Assessment of Cancer Therapy General, Breast Cancer, and Endocrine Symptom Scales), and the Greene Climacteric Scale...
May 9, 2017: Maturitas
https://www.readbyqxmd.com/read/28501958/heightened-perception-of-breast-cancer-risk-in-young-women-at-risk-of-familial-breast-cancer
#2
Rachael Glassey, Moira O'Connor, Angela Ives, Christobel Saunders, Sarah O'Sullivan, Sarah J Hardcastle
The objective of this study was to explore the factors that influence perceived personal risk of developing breast cancer (BC) in younger women (<35) who are considering or have undergone bilateral prophylactic mastectomy (BPM). Qualitative interviews guided by interpretative phenomenological analysis were conducted with 46 women who had a strong family history of BC and had either undergone (n = 26) or were considering (n = 20) BPM. Participants were recruited from Australia and New Zealand via hospitals, a genetics clinic, a research cohort, a registry and online...
May 13, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28473176/managing-menopausal-symptoms-after-breast-cancer-a-multidisciplinary-approach
#3
REVIEW
Paul A Cohen, Annabelle Brennan, Jennifer L Marino, Christobel M Saunders, Martha Hickey
More than 6 million women worldwide are living with a past diagnosis of breast cancer. Most survive their illness, and management of the long-term consequences of treatment has become a priority in cancer care. Menopausal symptoms affect most breast cancer survivors and may significantly impair quality of life. We describe a multidisciplinary model to evaluate and manage these women using a patient-focused approach. The 'Multidisciplinary Menopause After Cancer Clinic' includes gynecologists, endocrinologists, GPs, a psychologist and a clinical nurse specialist...
April 22, 2017: Maturitas
https://www.readbyqxmd.com/read/28357171/value-based-care-in-the-worldwide-battle-against-cancer
#4
REVIEW
Niloufer J Johansen, Christobel M Saunders
Globally, an increasing and aging population is contributing to the prevalence of cancer. To be effective, cancer care needs to involve the coordination of multidisciplinary specialties, and also needs to be affordable, accessible, and capable of producing optimal patient outcomes. Porter and Teisberg (2006) have postulated that shifting current healthcare strategies from volume-based to patient-centric care redirects economic competition to providing treatments which promote the best patient outcomes while driving down costs...
February 17, 2017: Curēus
https://www.readbyqxmd.com/read/28197122/commentary-bilateral-risk-reducing-mastectomy-is-the-safest-strategy-in-brca1-carriers
#5
COMMENT
Rachael Glassey, Christobel Saunders, Sarah J Hardcastle
No abstract text is available yet for this article.
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28105750/development-of-a-peer-review-framework-for-cancer-multi-disciplinary-meetings
#6
Claire E Johnson, Neli Slavova-Azmanova, Christobel Saunders
BACKGROUND: There is no mechanism in place for monitoring or quality improvement of cancer multidisciplinary meetings (MDMs) in Australia. OBJECTIVE: To develop a peer review process for quality improvement of MDMs. METHODS: This project involved three phases: 1) development of a draft peer review framework, supporting documents and peer review process; 2) consultation with key stakeholders; 3) refinement of the framework, documents and processes following a pilot study with three MDMs...
January 20, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28096010/a-pilot-study-of-routine-screening-for-distress-by-a-nurse-and-psychologist-in-an-outpatient-haematological-oncology-clinic
#7
Toni Musiello, Glenys Dixon, Moira O'Connor, Deb Cook, Lisa Miller, Anna Petterson, Christobel Saunders, David Joske, Claire Johnson
AIM: To explore the: 1) prevalence of distress, type of problems experienced by haematological patients, and referrals for supportive care; 2) effect of demographic and clinical variables on distress, and 3) effect on the time of health professionals conducting the screening in the ambulatory chemotherapy setting. METHODS: Participants completed the National Comprehensive Cancer Network Distress Thermometer and Problem List and had a follow-up screening discussion with a health professional...
February 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28033439/a-standard-set-of-value-based-patient-centered-outcomes-for-breast-cancer-the-international-consortium-for-health-outcomes-measurement-ichom-initiative
#8
Wee Loon Ong, Maartje G Schouwenburg, Annelotte C M van Bommel, Caleb Stowell, Kim H Allison, Karen E Benn, John P Browne, Rodney D Cooter, Geoff P Delaney, Francois P Duhoux, Patricia A Ganz, Patricia Hancock, Reshma Jagsi, Felicia M Knaul, Anne M Knip, Linetta B Koppert, Henry M Kuerer, Sarah McLaughin, Marc A M Mureau, Ann H Partridge, Dereesa Purtell Reid, Lisa Sheeran, Thomas J Smith, Mark J Stoutjesdijk, Marie Jeanne T F D Vrancken Peeters, Yvonne Wengström, Cheng-Har Yip, Christobel Saunders
A major challenge in value-based health care is the lack of standardized health outcomes measurements, hindering optimal monitoring and comparison of the quality of health care across different settings globally. The International Consortium for Health Outcomes Measurement (ICHOM) assembled a multidisciplinary international working group, comprised of 26 health care providers and patient advocates, to develop a standard set of value-based patient-centered outcomes for breast cancer (BC). The working group convened via 8 teleconferences and completed a follow-up survey after each meeting...
May 1, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/27991859/breath-mass-ion-biomarkers-of-breast-cancer
#9
Michael Phillips, Renee Cataneo, Cassie Lebauer, Mayur Mundada, Christobel Saunders
BACKGROUND: Breath volatile organic compounds (VOCs) contain biomarkers of breast cancer that are detectable with gas chromatography mass spectrometry (GC MS). However, chemical identification of breath VOC biomarkers may be erroneous because spectral matching can misidentify their structure. Breath mass ions detected with GC MS have been proposed as intrinsically robust biomarkers because they can be identified without spectral matching. We investigated whether breath mass ion biomarkers could identify breast cancer...
December 19, 2016: Journal of Breath Research
https://www.readbyqxmd.com/read/27987454/patient-reported-outcomes-in-ductal-carcinoma-in-situ-a-systematic-review
#10
REVIEW
Madeleine T King, Zoë E Winters, Ivo A Olivotto, Andrew J Spillane, Boon H Chua, Christobel Saunders, A Helen Westenberg, G Bruce Mann, Petrina Burnett, Phyllis Butow, Claudia Rutherford
Ductal carcinoma in situ (DCIS) is a pre-invasive breast cancer with excellent prognosis but with potential adverse impacts of diagnosis and treatment on quality of life and other patient-reported outcomes (PROs). We undertook a systematic review to synthesise current evidence about PROs following diagnosis and treatment for DCIS. We searched five electronic databases (from database inception to November 2015), cross-referenced and contacted experts to identify studies that reported PROs after DCIS treatment...
January 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/27867721/wide-field-optical-coherence-micro-elastography-for-intraoperative-assessment-of-human-breast-cancer-margins
#11
Wes M Allen, Lixin Chin, Philip Wijesinghe, Rodney W Kirk, Bruce Latham, David D Sampson, Christobel M Saunders, Brendan F Kennedy
Incomplete excision of malignant tissue is a major issue in breast-conserving surgery, with typically 20 - 30% of cases requiring a second surgical procedure arising from postoperative detection of an involved margin. We report advances in the development of a new intraoperative tool, optical coherence micro-elastography, for the assessment of tumor margins on the micro-scale. We demonstrate an important step by conducting whole specimen imaging in intraoperative time frames with a wide-field scanning system acquiring mosaicked elastograms with overall dimensions of ~50 × 50 mm, large enough to image an entire face of most lumpectomy specimens...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27829404/investigation-of-optical-coherence-micro-elastography-as-a-method-to-visualize-micro-architecture-in-human-axillary-lymph-nodes
#12
Kelsey M Kennedy, Lixin Chin, Philip Wijesinghe, Robert A McLaughlin, Bruce Latham, David D Sampson, Christobel M Saunders, Brendan F Kennedy
BACKGROUND: Evaluation of lymph node involvement is an important factor in detecting metastasis and deciding whether to perform axillary lymph node dissection (ALND) in breast cancer surgery. As ALND is associated with potentially severe long term morbidity, the accuracy of lymph node assessment is imperative in avoiding unnecessary ALND. The mechanical properties of malignant lymph nodes are often distinct from those of normal nodes. A method to image the micro-scale mechanical properties of lymph nodes could, thus, provide diagnostic information to aid in the assessment of lymph node involvement in metastatic cancer...
November 9, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27810485/breast-cancer-risk-and-the-interaction-between-adolescent-body-size-and-weight-gain-in-later-life-a-case-control-study
#13
Ines Florath, Danja Sarink, Christobel Saunders, Jane Heyworth, Lin Fritschi
BACKGROUND: While the breast cancer risk associated with increasing adult BMI in postmenopausal women can be explained by increases in concentrations of endogenous estrogens the biologic mechanisms behind the inverse association between adolescent BMI and breast cancer risk are still a subject of controversial debate. METHODS: We investigated the association of breast cancer with body size and changes in body size across life time estimated by age-specific BMI Z scores and changes in BMI Z scores from teenage years to middle age in an age-matched population-based case-control study of 2994 Australian women...
December 2016: Cancer Epidemiology
https://www.readbyqxmd.com/read/27784140/not-all-ductal-carcinoma-in-situ-is-created-equal-can-we-avoid-surgery-for-low-risk-ductal-carcinoma-in-situ
#14
REVIEW
Jocelyn Lippey, Andrew Spillane, Christobel Saunders
No abstract text is available yet for this article.
November 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27739214/switching-between-endocrine-therapies-for-primary-breast-cancer-frequency-and-timing-in-australian-clinical-practice
#15
Anna Kemp-Casey, Elizabeth E Roughead, Christobel Saunders, Frances Boyle, Max Bulsara, David B Preen
AIMS: To determine the frequency, timing and patterns of endocrine therapy switching in Australian practice for postmenopausal women with primary breast cancer. METHODS: We identified postmenopausal women in a population-based cohort commencing endocrine therapy for invasive primary breast cancer between December 2005 and December 2008 (n = 645). Individual-level administrative health records and self-report data were used to determine women's demographic and clinical characteristics, including preexisting and newly-treated comorbidities, and switches in endocrine therapy...
April 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27701839/breast-localization-techniques-and-margin-definitions-used-by-australian-and-new-zealand-surgeons
#16
Donna B Taylor, Anita G Bourke, Max M Hobbs, Glenys Dixon, Michael Phillips, Christobel M Saunders
No abstract text is available yet for this article.
October 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27689969/an-international-randomised-controlled-trial-to-compare-targeted-intraoperative-radiotherapy-targit-with-conventional-postoperative-radiotherapy-after-breast-conserving-surgery-for-women-with-early-stage-breast-cancer-the-targit-a-trial
#17
Jayant S Vaidya, Frederik Wenz, Max Bulsara, Jeffrey S Tobias, David J Joseph, Christobel Saunders, Chris Brew-Graves, Ingrid Potyka, Stephen Morris, Hrisheekesh J Vaidya, Norman R Williams, Michael Baum
BACKGROUND: Based on our laboratory work and clinical trials we hypothesised that radiotherapy after lumpectomy for breast cancer could be restricted to the tumour bed. In collaboration with the industry we developed a new radiotherapy device and a new surgical operation for delivering single-dose radiation to the tumour bed - the tissues at highest risk of local recurrence. We named it TARGeted Intraoperative radioTherapy (TARGIT). From 1998 we confirmed its feasibility and safety in pilot studies...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27684037/streamlined-genetic-education-is-effective-in-preparing-women-newly-diagnosed-with-breast-cancer-for-decision-making-about-treatment-focused-genetic-testing-a-randomized-controlled-noninferiority-trial
#18
Veronica F Quinn, Bettina Meiser, Judy Kirk, Kathy M Tucker, Kaaren J Watts, Belinda Rahman, Michelle Peate, Christobel Saunders, Elizabeth Geelhoed, Margaret Gleeson, Kristine Barlow-Stewart, Michael Field, Marion Harris, Yoland C Antill, Linda Cicciarelli, Karen Crowe, Michael T Bowen, Gillian Mitchell
PURPOSE: Increasingly, women newly diagnosed with breast cancer are being offered treatment-focused genetic testing (TFGT). As the demand for TFGT increases, streamlined methods of genetic education are needed. METHODS: In this noninferiority trial, women aged <50 years with either a strong family history (FH+) or other features suggestive of a germ-line mutation (FH-) were randomized before definitive breast cancer surgery to receive TFGT education either as brief written materials (intervention group (IG)) or during a genetic counseling session at a familial cancer clinic (usual-care group (UCG))...
September 29, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27682335/exploring-breast-health-practices-of-post-menopausal-women-implications-to-informed-consent
#19
Kristen Seaman, Peta Dzidic, Lauren Breen, Christobel Saunders
In light of the contention surrounding breast health practices, the research aimed to explore post-menopausal women's experiences of such practices. Semi-structured interviews were conducted in July and August 2015 with 13 Australian women aged 54-74 years. Data were analysed thematically. Participants deemed their engagement with breast health practices as the 'right' thing. However, engaging in these 'right' practices appeared to be fostered by misconceptions. The findings suggest that women may not be making evidence-informed decisions to engage in breast screening; identify contemporary barriers to promoting informed decisions; and may inform information pertinent to breast screening policy, campaigns and decision aid designs...
September 28, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27618159/simplifying-the-assessment-of-human-breast-cancer-by-mapping-a-micro-scale-heterogeneity-index-in-optical-coherence-elastography
#20
Lixin Chin, Bruce Latham, Christobel M Saunders, David D Sampson, Brendan F Kennedy
Surgical treatment of breast cancer aims to identify and remove all malignant tissue. Intraoperative assessment of tumor margins is, however, not exact; thus, re-excision is frequently needed, or excess normal tissue is removed. Imaging methods applicable intraoperatively could help to reduce re-excision rates whilst minimizing removal of excess healthy tissue. Optical coherence elastography (OCE) has been proposed for use in breast-conserving surgery; however, intraoperative interpretation of complex OCE images may prove challenging...
May 2017: Journal of Biophotonics
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