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https://www.readbyqxmd.com/read/29778434/implementation-of-multimodal-infection-control-and-hand-hygiene-strategies-in-acute-care-hospitals-in-greece-a-cross-sectional-benchmarking-survey
#1
Evangelos I Kritsotakis, Eirini Astrinaki, Argyri Messaritaki, Achilleas Gikas
BACKGROUND: In this first attempt to suggest achievable standards for improvement in hospital infection prevention and control (IPC) in Greece, we assessed main IPC structure and process indicators emphasizing hand hygiene. METHODS: Acute-care hospitals across the country participated in a cross-sectional survey by completing the World Health Organization Hand Hygiene Self-assessment Framework (HHSAF) and by providing hospital-level IPC indicators. RESULTS: Seventeen hospitals completed the survey, comprising 14% of the country's public hospitals...
May 16, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29777967/rates-and-correlates-of-disordered-eating-among-women-veterans-in-primary-care
#2
Laura J Buchholz, Paul R King, Laura O Wray
Rates of disordered eating may be higher among women veterans than civilians, and are associated with co-occurring mental health (MH) conditions, such as depression, post-traumatic stress disorder (PTSD), and alcohol misuse. Although evidence suggests that these conditions are common in primary care settings, limited research has examined symptoms of disordered eating among women veterans in primary care. This study used a cross-sectional design to examine rates and MH correlates of disordered eating among women veterans treated in a primary care setting...
May 16, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29777853/investigation-of-the-potential-endocrine-effect-of-nitrate-in-zebrafish-danio-rerio-and-brown-trout-salmo-trutta
#3
Poul Bjerregaard, Karin Lund Kinnberg, Maria Pedersen Mose, Henrik Holbech
Nitrate has the potential to affect steroid production. Nitrate concentrations in streams in agricultural areas may exceed concentrations showing effects in laboratory studies. The effects of nitrate and/or nitrite on endocrine relevant endpoints were tested in zebrafish and brown trout. Zebrafish were exposed in two experiments to nitrate (8.8 to 89 mg NO3 - /L) and nitrite (3.6 to 19 mg NO2 - /L) during the period of sexual differentiation and sex ratios were determined. Vitellogenin concentrations were determined in the second experiment...
May 16, 2018: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/29777731/tumor-necrosis-factor-receptor-2-is-required-for-ischemic-preconditioning-mediated-neuroprotection-in-the-hippocampus-following-a-subsequent-longer-transient-cerebral-ischemia
#4
Jae-Chul Lee, Chan Woo Park, Myoung Cheol Shin, Jun Hwi Cho, Hyang-Ah Lee, Young-Myeong Kim, Joon Ha Park, Ji Hyeon Ahn, Jeong Hwi Cho, Hyun-Jin Tae, In Koo Hwang, Tae-Kyeong Lee, Moo-Ho Won, Il Jun Kang
Tumor Necrosis Factor-α (TNF-α) is a proinflammatory cytokine implicated in neuronal damage in response to cerebral ischemia. Ischemic preconditioning (IPC) provides neuroprotection against a subsequent severer or longer transient ischemia by ischemic tolerance. Here, we focused on the role of TNF-α in IPC-mediated neuroprotection against neuronal death following a subsequent longer transient cerebral ischemia (TCI). Gerbils used in this study were randomly assigned to eight groups; sham group, TCI operated group, IPC plus (+) sham group, IPC + TCI operated group, sham + etanercept (an inhibitor of TNF-a) group, TCI + etanercept group, IPC + sham + etanercept group, and IPC + TCI + etanercept group...
May 16, 2018: Neurochemistry International
https://www.readbyqxmd.com/read/29775963/brain-ischemic-preconditioning-protects-against-ischemic-injury-and-preserves-the-blood-brain-barrier-via-oxidative-signaling-and-nrf2-activation
#5
Tuo Yang, Yang Sun, Leilei Mao, Meijuan Zhang, Qianqian Li, Lili Zhang, Yejie Shi, Rehana K Leak, Jun Chen, Feng Zhang
Brain ischemic preconditioning (IPC) with mild ischemic episodes is well known to protect the brain against subsequent ischemic challenges. However, the underlying mechanisms are poorly understood. Here we demonstrate the critical role of the master redox transcription factor, nuclear factor (erythroid-derived 2)-like 2 (Nrf2), in IPC-mediated neuroprotection and blood-brain barrier (BBB) preservation. We report that IPC causes generation of endogenous lipid electrophiles, including 4-hydroxy-2-nonenal (4-HNE), which release Nrf2 from inhibition by Keap1 (via Keap1-C288) and inhibition by glycogen synthase kinase 3β (via GSK3β-C199)...
May 6, 2018: Redox Biology
https://www.readbyqxmd.com/read/29766336/ischaemic-preconditioning-protects-cardiomyocytes-from-anthracycline-induced-toxicity-via-the-pi3k-pathway
#6
Angshuman Maulik, Sean M Davidson, Izabela Piotrowska, Malcolm Walker, Derek M Yellon
PURPOSE: Anthracyclines cause chronic irreversible cardiac failure, but the mechanism remains poorly understood. Emerging data indicate that cardiac damage begins early, suggesting protective modalities delivered in the acute stage may confer prolonged benefit. Ischaemic preconditioning (IPC) activates the pro-survival reperfusion injury salvage kinase (RISK) pathway which involves PI3-kinase and MAPK/ERK1/2. METHODS: We investigated whether simulated IPC (sIPC), in the form of a sublethal exposure to a hypoxic buffer simulating ischaemic conditions followed by reoxygenation, protects primary adult rat cardiomyocytes against anthracycline-induced injury...
May 15, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29765800/surface-characterization-of-nanoparticles-using-near-field-light-scattering
#7
Eunsoo Yoo, Yizhong Liu, Chukwuazam A Nwasike, Sebastian R Freeman, Brian C DiPaolo, Bernardo Cordovez, Amber L Doiron
The effect of nanoparticle surface coating characteristics on colloidal stability in solution is a critical parameter in understanding the potential applications of nanoparticles, especially in biomedicine. Here we explored the modification of the surface of poly(ethylene glycol)-coated superparamagnetic iron oxide nanoparticles (PEG-SPIOs) with the synthetic pseudotannin polygallol via interpolymer complexation (IPC). Changes in particle size and zeta potential were indirectly assessed via differences between PEG-SPIOs and IPC-SPIOs in particle velocity and scattering intensity using near-field light scattering...
2018: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/29765476/developmental-trends-of-theta-beta-interelectrode-power-correlation-during-resting-state-in-normal-children
#8
Ernesto Buiza, Elena I Rodríguez-Martínez, Catarina I Barriga-Paulino, Antonio Arjona, Carlos M Gómez
The possibility that power-to-power (theta-beta) frequency coupling increases during development was analyzed. Three minutes of spontaneous EEG in an open eyes condition were recorded in a sample of 160 subjects ranging from 6 to 26 years old. Theta (4-7 Hz) and beta band (15-20 Hz) power was calculated in a trial-by-trial basis. Inter-electrode power correlations (IPC) were computed in each subject as the correlation between the power of two frequency bands recorded in two electrodes. An increase in theta-beta IPC with age was obtained...
June 2018: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29764447/efficacy-of-intra-articular-hypertonic-dextrose-prolotherapy-versus-normal-saline-for-knee-osteoarthritis-a-protocol-for-a-triple-blinded-randomized-controlled-trial
#9
Regina Wing Shan Sit, Ricky Wing Keung Wu, Kenneth Dean Reeves, David Rabago, Dicken Cheong Chun Chan, Benjamin Hon Kei Yip, Vincent Chi Ho Chung, Samuel Yeung Shan Wong
BACKGROUND: Knee Osteoarthritis (KOA) is a very common condition with prevalence rising with age. It is a major contributor to global disability and has a large socioeconomic burden worldwide. Conservative therapies have marginal effectiveness, and surgery is reserved for severe symptomatic KOA. Dextrose Prolotherapy (DPT) is an evidence-based injection-based therapy for chronic musculoskeletal conditions including KOA. The standard "whole joint" injection method includes intra-articular injection and multiple extra-articular injections at soft tissue bony attachments...
May 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29751254/isometric-pre-conditioning-blunts-exercise-induced-muscle-damage-but-does-not-attenuate-changes-in-running-economy-following-downhill-running
#10
Leonardo C R Lima, Natália M Bassan, Adalgiso C Cardozo, Mauro Gonçalves, Camila C Greco, Benedito S Denadai
Running economy (RE) is impaired following unaccustomed eccentric-biased exercises that induce muscle damage. It is also known that muscle damage is reduced when maximal voluntary isometric contractions (MVIC) are performed at a long muscle length 2-4 days prior to maximal eccentric exercise with the same muscle, a phenomenon that can be described as isometric pre-conditioning (IPC). We tested the hypothesis that IPC could attenuate muscle damage and changes in RE following downhill running. Thirty untrained men were randomly assigned into experimental or control groups and ran downhill on a treadmill (-15%) for 30 min...
May 8, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29743488/three-dimensional-hot-electron-photovoltaic-device-with-vertically-aligned-tio-2-nanotubes
#11
Kalyan C Goddeti, Changhwan Lee, Young Keun Lee, Jeong Young Park
Titanium dioxide (TiO2 ) nanotubes with vertically aligned array structures show substantial advantages in solar cells as an electron transport material that offers a large surface area where charges travel linearly along the nanotubes. Integrating this one-dimensional semiconductor material with plasmonic metals to create a three-dimensional plasmonic nanodiode can influence solar energy conversion by utilizing the generated hot electrons. Here, we devised plasmonic Au/TiO2 and Ag/TiO2 nanodiode architectures composed of TiO2 nanotube arrays for enhanced photon absorption, and for the subsequent generation and capture of hot carriers...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29740345/conduit-artery-diameter-during-exercise-is-enhanced-after-local-but-not-remote-ischemic-preconditioning
#12
Scott Cocking, N T Cable, Mathew G Wilson, Daniel J Green, Dick H J Thijssen, Helen Jones
Introduction: The ability of ischemic preconditioning (IPC) to enhance exercise capacity may be mediated through altering exercise-induced blood flow and/or vascular function. This study investigated the hypothesis that (local) IPC enhances exercise-induced blood flow responses and prevents decreases in vascular function following exercise. Methods: Eighteen healthy, recreationally trained, male participants (mean ± SD : age 32 ± 8 years; BMI 24.2 ± 2.3; blood pressure 122 ± 10/72 ± 8 mmHg; resting HR 58 ± 9 beats min-1 ) received IPC (220 mmHg; 4 × 5-min bilateral arms), REMOTE IPC (220 mmHg; 4 × 5-min bilateral legs), or SHAM (20 mmHg; 4 × 5-min bilateral arms) in a counterbalanced order prior to 30-min of submaximal (25% maximal voluntary contraction) unilateral rhythmic handgrip exercise...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29736337/influence-and-reliability-of-lower-limb-arterial-occlusion-pressure-at-different-body-positions
#13
Luke Hughes, Owen Jeffries, Mark Waldron, Ben Rosenblatt, Conor Gissane, Bruce Paton, Stephen D Patterson
Background: Total arterial occlusive pressure (AOP) is used to prescribe pressures for surgery, blood flow restriction exercise (BFRE) and ischemic preconditioning (IPC). AOP is often measured in a supine position; however, the influence of body position on AOP measurement is unknown and may influence level of occlusion in different positions during BFR and IPC. The aim of this study was therefore to investigate the influence of body position on AOP. Methods: Fifty healthy individuals (age = 29 ± 6 y) underwent AOP measurements on the dominant lower-limb in supine, seated and standing positions in a randomised order...
2018: PeerJ
https://www.readbyqxmd.com/read/29735821/changing-panorama-for-surveillance-of-device-associated-healthcare-infections-challenges-faced-in-implementation-of-current-guidelines
#14
REVIEW
Renu Gupta, Sangeeta Sharma, Sonal Saxena
Healthcare-associated infections (HAI) are preventable in up to 30% of patients with evidence-based infection prevention and control (IPC) activities. IPC activities require effective surveillance to generate data for the HAI rates, defining priority areas, identifying processes amenable for improvement and institute interventions to improve patient's safety. However, uniform, accurate and standardised surveillance methodology using objective definitions can only generate meaningful data for effective execution of IPC activities...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29729658/effect-of-intermittent-pneumatic-compression-on-preventing-deep-vein-thrombosis-among-stroke-patients-a-systematic-review-and-meta-analysis
#15
Dongdong Zhang, Fenfen Li, Xiaotian Li, Ganqin Du
BACKGROUND: Deep vein thrombosis (DVT) and subsequent pulmonary embolism (PE) are common complications of stroke. However, the effect of intermittent pneumatic compression (IPC) for patients after stroke is uncertain. OBJECTIVES: To assess the effectiveness and safety of IPC in reducing the risk of DVT, PE, and mortality in stroke patients. METHODS: We searched leading medical databases including Medline, EMBASE, Cochrane Library, Wanfang, CNKI, and CBM, from inception to June 2, 2017...
May 5, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29723070/examining-the-interpersonal-nature-of-criterion-a-of-the-dsm-5-section-iii-alternative-model-for-personality-disorders-using-bootstrapped-confidence-intervals-for-the-interpersonal-circumplex
#16
Emily A Dowgwillo, Michael J Roche, Aaron L Pincus
Criterion A of the alternative model of personality disorders (AMPD) involves the assessment of impairments in self and self in relation to other functioning and can be assessed using the Level of Personality Functioning Scale (LPFS). This study uses responses to a self-report version of the LPFS (AMPD-CAS) from 248 college students to examine the interpersonal implications of AMPD personality impairments using the interpersonal circumplex (IPC) as a nomological net. Results suggest that AMPD-CAS self-impairments are related to problems of low communion and interpersonal distress and do not appear to tap expected interpersonal problems of low agency...
May 3, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29722251/effects-of-local-versus-remote-ischemic-preconditioning-on-repeated-sprint-running-performance
#17
Patrick J Griffin, Luke Hughes, Conor Gissane, Stephen D Patterson
BACKGROUND: The aim of this study was to compare the effect of local and remote ischemic preconditioning (IPC) on repeated sprint exercise. METHODS: Twelve males (age 22 ± 2 years; stature 1.79±0.07 m; body mass 77.8±8.4 kg; mean ± SD) completed four trials consisting of remote (arm) and local (leg) IPC and SHAM interventions prior to repeated sprint exercise (3 x (6 x 15 + 15-m) shuttle sprints), in a double-blind, randomised, crossover designed study. These tests were immediately preceded by IPC (4 x 5 minute intervals at 220 mmHg bilateral occlusion) or SHAM treatment (4 x 5 minute intervals at 20 mmHg bilateral occlusion)...
May 2, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29719413/intermittent-pneumatic-compression-is-a-cost-effective-method-of-orthopedic-postsurgical-venous-thromboembolism-prophylaxis
#18
Rhodri Saunders, Anthony J Comerota, Audrey Ozols, Rafael Torrejon Torres, Kwok Ming Ho
Background: Venous thromboembolism (VTE) is a major complication after lower-limb arthroplasty that increases costs and reduces patient's quality of life. Using anticoagulants for 10-35 days following arthroplasty is the standard prophylaxis, but its cost-effectiveness after accounting for bleeding complications remains unproven. Methods: A comprehensive, clinical model of VTE was created using the incidences, clinical effects (including bleeding), and costs of VTE and prophylaxis from randomized controlled trials, meta-analyses, and large observational studies...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29717319/two-step-electrodeposition-to-fabricate-the-p-n-heterojunction-of-a-cu-2-o-bivo-4-photoanode-for-the-enhancement-of-photoelectrochemical-water-splitting
#19
Shouli Bai, Jingchao Liu, Meng Cui, Ruixian Luo, Jing He, Aifan Chen
A Cu2O/BiVO4 p-n heterojunction based photoanode in photoelectrochemical (PEC) water splitting is fabricated by a two-step electrodeposition method on an FTO substrate followed by annealing treatment. The structures and properties of the samples are characterized by XRD, FESEM, HRTEM, XPS and UV-visible spectra. The photoelectrochemical activity of the photoanode in water oxidation has been investigated and measured in a three electrode quartz cell system; the obtained maximum photocurrent density of 1.72 mA cm-2 at 1...
May 2, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29713161/role-of-au-nps-in-the-enhanced-response-of-au-nps-decorated-mwcnt-electrochemical-biosensor
#20
Shahid Mehmood, Regina Ciancio, Elvio Carlino, Arshad S Bhatti
Background: The combination of Au-metallic-NPs and CNTs are a new class of hybrid nanomaterials for the development of electrochemical biosensor. Concentration of Au(nanoparticles [NPs]) in the electrochemical biosensor is crucial for the efficient charge transfer between the Au-NPs-MWCNTs modified electrode and electrolytic solution. Methods: In this work, the charge transfer kinetics in the glassy carbon electrode (GCE) modified with Au(NPs)-multiwalled carbon nanotube (MWCNT) nanohybrid with varied concentrations of Au(NPs) in the range 40-100 nM was studied using electrochemical impedance spectroscopy (EIS)...
2018: International Journal of Nanomedicine
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