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https://www.readbyqxmd.com/read/29155579/catalytic-conversion-of-carbohydrates-to-initial-platform-chemicals-chemistry-and-sustainability
#1
László T Mika, Edit Cséfalvay, Áron Németh
The replacement of fossil resources that currently provide more than 90% of our energy needs and feedstocks of the chemical industry in combination with reduced emission of carbon dioxide is one of the most pressing challenges of mankind. Biomass as a globally available resource has been proposed as an alternative feedstock for production of basic building blocks, which could partially or even fully replace the currently utilized fossil-based ones in well-established chemical processes. The destruction of lignocellulosic feed followed by oxygen removal from its cellulose and hemicellulose content by catalytic processes results in the formation of initial platform chemicals (IPCs)...
November 20, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/29150935/generation-of-insulin-producing-cells-from-human-adipose-derived-mesenchymal-stem-cells-on-pva-scaffold-by-optimized-differentiation-protocol
#2
Seyed Ehsan Enderami, Masoud Soleimani, Yousef Mortazavi, Samad Nadri, Ali Salimi
The studies have been done on patient-specific human adipose-derived from mesenchymal stem cells (hADSCs) like a series of autologous growth factors and nanofibrous scaffolds (3D culture) will probably have many benefits for regenerative medicine in type 1 diabetes mellitus (TIDM) patients in the future. For this purpose, we established a polyvinyl alcohol (PVA) scaffold and a differentiation protocol by adding platelet-rich plasma (PRP) that induces the hADSCs into insulin-producing cells (IPCs). The Characteristics of the derived IPCs in 3D culture were compared with conventional culture (2D) groups evaluated at the mRNA and protein levels...
November 18, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29148140/haemodynamic-effects-of-an-acute-vasodilator-challenge-in-heart-failure-patients-with-reduced-ejection-fraction-and-different-forms-of-post-capillary-pulmonary-hypertension
#3
Stefano Ghio, Gabriele Crimi, Pier Luigi Temporelli, Egidio Traversi, Maria Teresa La Rovere, Antonia Cannito, Dario Vizza, Laura Scelsi, Claudia Raineri, Marco Guazzi, Luigi Oltrona Visconti
AIMS: The most recent European guidelines have proposed new definitions of pulmonary hypertension (PH) in left heart disease, to better approach the characteristics required to reflect the presence of pulmonary vascular disease. The purpose of this study was to assess whether different haemodynamic definitions of post-capillary PH imply a different reversibility of PH in response to acute vasodilator administration in heart failure patients with reduced ejection fraction and PH (HFrEF-PH)...
November 16, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29146161/intraoperative-workflow-for-all-inside-anterior-cruciate-ligament-reconstruction-an-in%C3%A2-vitro-biomechanical-evaluation-of-preconditioning-and-knot-tying
#4
Edoardo Monaco, Samuel Bachmaier, Mattia Fabbri, Riccardo Maria Lanzetti, Coen A Wijdicks, Andrea Ferretti
PURPOSE: To evaluate and compare the effect of preconditioning according to intraoperative workflow on the elongation behavior of single-side and fully knotted all-inside anterior cruciate ligament (ACL) reconstruction configurations in a biomechanical in vitro study. METHODS: Four full construct all-inside ACL reconstruction groups (n = 8 per group) were tested using porcine tibias and bovine tendons. Groups included both an all-inside configuration with one- (group 1) and both-side knotted adjustable loop-length devices (group 2), without and with performing intraoperative preconditioning (group 1-intraoperative preconditioned [IPC], group 2-IPC)...
November 13, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29145037/time-to-diagnosis-and-treatment-for-cancer-patients-in-the-netherlands-room-for-improvement
#5
Charles C W Helsper, Nicole N F van Erp, Petra P H M Peeters, Niek N J de Wit
BACKGROUND & AIM: Reducing the duration of the diagnostic cancer care pathway is intensively pursued. The aim of this study was to chart the diagnostic pathway for the five most common cancers in the Netherlands. METHODS: A retrospective cohort study using cancer patients' anonymised primary care data (free text and coded) linked to the Netherlands Cancer Registry. We determined the median duration of the following: 1. Primary care intervals (IPCs): the first cancer-related general practitioner consultation to referral, 2...
November 13, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29144793/interprofessional-collaboration-an-exploration-of-possible-prerequisites-for-successful-implementation
#6
Erik Vestergaard, Birgitte Nørgaard
Poor collaboration among professional groups may be a major cause of incoherent patient pathways in hospital settings. For over a decade, interprofessional collaboration (IPC) have been stressed as an effective method to enhance the delivery of patient care. This article presents a theory-based stakeholder evaluation of the implementation of an intervention aiming to implement the concept of IPC in a Danish regional hospital from 2012 to 2015. Involving five departments and eight professions, the intervention aimed at developing coherent practices across health professions by optimising patient pathways with the establishment of interprofessional teams as a core element...
November 16, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29140780/full-body-animation-of-human-locomotion-in-reduced-gravity-using-physics-based-control
#7
Yun-Hyeong Kim, Taesoo Kwon, Daeun Song, Young J Kim
The proposed physics-based approach can generate stable and robust full-body animation of various gaits under different gravitational conditions. As input, this method takes motion-captured human motions in the Earth's gravity and builds an inverted-pendulum on cart (IPC) control model, which is analyzed using the motion-captured data. The authors use a pre-estimation model based on the Froude number to predict the desired velocity and stride frequency of a character model in hypogravity and then generate full-body animation using a pendulum trajectory generator, motion planner, and tracking...
November 2017: IEEE Computer Graphics and Applications
https://www.readbyqxmd.com/read/29137632/descriptive-study-of-interprofessional-collaboration-between-physicians-and-osteopaths-for-the-pediatric-population-in-quebec-canada
#8
Chantal Morin, Johanne Desrosiers, Isabelle Gaboury
BACKGROUND: Osteopathy is an increasingly popular healthcare approach that uses a wide variety of therapeutic manual techniques to address pain and somatic dysfunction. In Quebec, Canada, osteopathy is the complementary medicine most often recommended by family physicians. However, factors fostering the development of interprofessional collaboration (IPC) between physicians and osteopaths are unknown. This study aimed to describe the current situation in terms of IPC among practitioners working with pediatric patients...
November 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29133211/beta-lactam-resistance-among-enterobacteriaceae-in-cambodia-the-four-year-itch
#9
REVIEW
Yannick Caron, Rattanak Chheang, Puthea Nop, Soda Meng, Sébastien Boyer, Arnaud Tarantola, Alexandra Kerléguer
Although antibiotics are too often used inappropriately in Cambodia, few data have been published on antimicrobial resistance in this country. Epidemic dissemination and the transfer of resistance genes to other bacterial species put the population at risk. The aim of this study was to evaluate the frequency and characteristics of extended-spectrum beta-lactamase (ESBL) enterobacteriaceae (ESBL-E) isolated in consecutive samples tested at Institut Pasteur du Cambodge (IPC) over a four-year period (2012-2015)...
November 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29122781/simulation-based-inter-professional-education-to-improve-attitudes-towards-collaborative-practice-a-prospective-comparative-pilot-study-in-a-chinese-medical-centre
#10
Ling-Yu Yang, Ying-Ying Yang, Chia-Chang Huang, Jen-Feng Liang, Fa-Yauh Lee, Hao-Min Cheng, Chin-Chou Huang, Shou-Yen Kao
OBJECTIVES: Inter-professional education (IPE) builds inter-professional collaboration (IPC) attitude/skills of health professionals. This interventional IPE programme evaluates whether benchmarking sharing can successfully cultivate seed instructors responsible for improving their team members' IPC attitudes. DESIGN: Prospective, pre-post comparative cross-sectional pilot study. SETTING/PARTICIPANTS: Thirty four physicians, 30 nurses and 24 pharmacists, who volunteered to be trained as seed instructors participated in 3...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29121919/effects-of-hypoglycemia-on-myocardial-susceptibility-to-ischemia-reperfusion-injury-and-preconditioning-in-hearts-from-rats-with-and-without-type-2-diabetes
#11
Kim B Pælestik, Nichlas R Jespersen, Rebekka V Jensen, Jacob Johnsen, Hans Erik Bøtker, Steen B Kristiansen
BACKGROUND: Hypoglycemia is associated with increased mortality rate in patients with diabetes. The underlying mechanisms may involve reduced myocardial tolerance to ischemia and reperfusion (IR) or reduced capacity for ischemic preconditioning (IPC). As IPC is associated with increased myocardial glucose uptake (MGU) during reperfusion, cardioprotection is linked to glucose metabolism possibly by O-linked β-N-acetylglucosamine (O-GlcNAc). We aimed to investigate the impact of hypoglycemia in hearts from animals with diabetes on myocardial IR tolerance, on the efficacy of IPC and whether modulations of MGU and O-GlcNAc levels are involved in the underlying mechanisms...
November 9, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29121035/ischemic-conditioning-of-human-heart-muscle-depends-on-opioid-receptor-system
#12
Marcin Kunecki, Tomasz Oleksy, Jolanta Biernat, Paweł Kukla, Katarzyna Szwajkos, Piotr Podolec, Marek Deja, Krzysztof Gołba, Wojciech Płazak
BACKGROUND: Despite progress in the invasive treatment of ischemic heart disease, the ability to limit ischemia-reperfusion (I/R) injury remains largely unrealized. Ischemic pre-conditioning (IPC) and post-conditioning (POC) induce the protective mechanisms of resistance against I/R injury. Stimulation of opioid receptors mimic the protective effect of IPC or POC in an animal models. We tested the hypothesis, that IPC and POC provide cardioprotection in opioid-dependent mechanism in human myocardium...
2017: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/29120009/challenges-in-interprofessionalism-in-swiss-health-care-the-practice-of-successful-interprofessional-collaboration-as-experienced-by-professionals
#13
Christof Schmitz, Gina Atzeni, Peter Berchtold
The topic of interprofessional collaboration (IPC) between healthcare professionals has been widely discussed in recent years. Whereas the growing calls for more and better IPC can scarcely be ignored and a broad range of definitions and normative concepts have been proposed, it remains unclear what IPC actually means for practising professionals. This exploratory survey investigated the various ways in which successful IPC is understood in practice. As a main finding of the study, we were able to identify three distinct modes of collaboration between different professions in health care...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29118251/interprofessional-education-in-dental-hygiene-programs-and-coda-standards-dental-hygiene-program-directors-perspectives
#14
Danielle Furgeson, Marita Rohr Inglehart
Purpose: The Patient Protection and Affordable Care Act changed the paradigm of health care delivery by addressing interprofessional education (IPE) and care (IPC). These considerations, combined with evolving dental hygiene (DH) workforce models, challenge DH educators and clinicians alike to embrace IPE and IPC. The objectives of this study were to determine DH program directors' perceptions of the importance of IPE, to assess current and planned activities related to Commission on Dental Accreditation (CODA) standards that imply competency in IPE, and assessment of outcomes...
April 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29116868/a-multiple-group-measurement-scale-for-interprofessional-collaboration-adaptation-and-validation-into-italian-and-german-languages
#15
Fabio Vittadello, Maria Mischo-Kelling, Heike Wieser, Luisa Cavada, Lukas Lochner, Carla Naletto, Verena Fink, Scott Reeves
This article presents a study that aimed to validate a translation of a multiple-group measurement scale for interprofessional collaboration (IPC). We used survey data gathered over a three month period as part of a mixed methods study that explored the nature of IPC in Northern Italy. Following a translation from English into Italian and German the survey was distributed online to over 5,000 health professionals (dieticians, nurses, occupational therapists, physicians, physiotherapists, speech therapists and psychologists) based in one regional health trust...
November 8, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29113372/efficacy-and-safety-of-intraperitoneal-chemotherapy-in-patients-with-advanced-gastric-cancer-a-cumulative-meta-analysis-of-randomized-controlled-trials
#16
Zheng He, Ting-Ting Zhao, Hui-Mian Xu, Zhen-Ning Wang, Ying-Ying Xu, Yong-Xi Song, Zhong-Ran Ni, Hao Xu, Song-Cheng Yin, Xing-Yu Liu, Zhi-Feng Miao
Even when a curative gastrectomy is conducted, the majority of advanced gastric cancer patients with invasion die due to peritoneal recurrence. We performed electronic searches to identify randomized controlled trials published through April 2017 evaluating the effect of intraperitoneal chemotherapy (IPC) on survival rates. We included 23 trials reporting data on 2,767 patients with advanced gastric cancer. Overall, we noted that patients who received IPC had a significantly increased 1-year survival rate, and the treatment effect of IPC on 1-year survival was most prominent in studies conducted in Japan or those with a mean age of less than 60 years...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29112625/ischemic-preconditioning-improves-time-trial-performance-at-moderate-altitude
#17
Pénélope Paradis-Deschênes, Denis R Joanisse, François Billaut
PURPOSE: Endurance athletes often compete and train at altitude where exercise capacity is reduced. Investigating acclimation strategies is therefore critical. Ischemic preconditioning (IPC) can improve endurance performance at sea level through improved O2 delivery and utilization, which could also prove beneficial at altitude. However, data are scarce and there is no study at altitudes commonly visited by endurance athletes. METHODS: In a randomized, crossover study, we investigated performance and physiological responses in thirteen male endurance cyclists during four 5-km cycling time trials (TT), preceded by either IPC (3x5-minutes ischemia/5-minutes reperfusion cycles at 220 mmHg) or SHAM (20 mmHg) administered to both thighs, at simulated low (FIO2 0...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29112550/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-mechanical-prophylaxis
#18
Arash Afshari, Christian Fenger-Eriksen, Manuel Monreal, Peter Verhamme
: Institutional protocols need to address the indications for pharmacological and mechanical thromboprophylaxis. The use of graduated compression stockings (GCS) and intermittent pneumatic compression (IPC) strongly differs between institutions. As a consequence, no strong recommendations can be made based on the contemporary high-level evidence. Although different clinical practices can be supported, such approaches should be part of an institutional strategy to reduce the burden of venous thromboembolism (VTE)...
November 6, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29112542/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-neurosurgery
#19
David Faraoni, Raquel Ferrandis, William Geerts, Matthew D Wiles
: Although there are numerous publications addressing venous thromboembolism and its prevention in neurosurgery, there are relatively few high-quality studies to guide decisions regarding thromboprophylaxis. In patients undergoing craniotomy, we recommend that if intermittent pneumatic compression (IPC) is used, it should be applied before the surgical procedure or on admission (Grade 1C). In craniotomy patients at particularly high risk for venous thromboembolism, we suggest considering the initiation of mechanical thromboprophylaxis with IPC preoperatively with addition of low molecular weight heparin (LMWH) postoperatively when the risk of bleeding is presumed to be decreased (Grade 2C)...
November 6, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29112541/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-cardiovascular-and-thoracic-surgery
#20
Aamer B Ahmed, Andreas Koster, Marcus Lance, David Faraoni
: None of the predictive models for venous thromboembolism (VTE) prophylaxis have been designed for and validated in patients undergoing cardiothoracic and vascular surgery. The presence of one or more risk factors [age over 70 years old, transfusion of more than 4 U of red blood cells/fresh frozen plasma/cryoprecipitate, mechanical ventilation lasting more than 24 h, postoperative complication (e.g. acute kidney injury, infection/sepsis, neurological complication)] should place the cardiac population at high risk for VTE...
November 6, 2017: European Journal of Anaesthesiology
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