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Mri scar mortality

Fatma Nur Korkmaz, Gulsen Ozen, Ali Uğur Ünal, Pınar Kahraman Koytak, Nese Tuncer, Haner Direskeneli
Abstract/ Resumo Behcet's disease (BD) is a multisystem inflammatory disorder characterized by recurrent oral and genital ulcers, skin lesions and uveitis. The nervous system involvement of BD, neuro-Behcet's disease (NBD), is one of the important causes of mortality of the disease. Herein, we present a 29-year-old male with parenchymal NBD who has progressed rapidly and was managed with an uncommon aggressive immunosuppresive combination therapy. The patient first presented six years ago with vertigo and difficulty in talking and walking...
September 28, 2016: Acta Reumatológica Portuguesa
Marwa A Sabe, Sharif A Sabe, Kenya Kusunose, Scott D Flamm, Brian P Griffin, Deborah H Kwon
BACKGROUND: Decreased right ventricular (RV) ejection fraction (RVEF) portends poor prognosis in patients with ischemic cardiomyopathy, and previous studies have suggested an association between mitral regurgitation (MR) and RVEF. We sought to evaluate this association and whether mitral valve repair or replacement affects the relationship between RV function and mortality. METHODS: We included 588 patients (mean age, 63±11 years; 75% male) with ischemic cardiomyopathy who underwent cardiac magnetic resonance imaging between 2002 and 2008...
August 30, 2016: Circulation
M F Malik, L R Hoyos, J Rodriguez-Kovacs, J Gillum, S C Johnson
Introduction. Cesarean scar pregnancies (CSPs) are one of the rarest forms of ectopic pregnancy. Given their rarity, there is lack of consensus regarding the management and natural course of CSPs. Case. A 37-year-old G10 P3063 female with a history of two prior cesarean deliveries was diagnosed with her second CSP at 6 weeks and 5 days in her tenth pregnancy. The patient underwent vertical hysterotomy, excision of a gestational sac implanted in the cesarean sac, and bilateral salpingectomy via a laparotomy incision...
2016: Case Reports in Obstetrics and Gynecology
Karl Roessler, Andrea Hofmann, Bjoern Sommer, Peter Grummich, Roland Coras, Burkard Sebastian Kasper, Hajo M Hamer, Ingmar Blumcke, Hermann Stefan, Christopher Nimsky, Michael Buchfelder
OBJECTIVE: Intraoperative overestimation of resection volume in epilepsy surgery is a well-known problem that can lead to an unfavorable seizure outcome. Intraoperative MRI (iMRI) combined with neuronavigation may help surgeons avoid this pitfall and facilitate visualization and targeting of sometimes ill-defined heterogeneous lesions or epileptogenic zones and may increase the number of complete resections and improve seizure outcome. METHODS: To investigate this hypothesis, the authors conducted a retrospective clinical study of consecutive surgical procedures performed during a 10-year period for epilepsy in which they used neuronavigation combined with iMRI and functional imaging (functional MRI for speech and motor areas; diffusion tensor imaging for pyramidal, speech, and visual tracts; and magnetoencephalography and electrocorticography for spike detection)...
March 2016: Neurosurgical Focus
Fabiola B Sozzi, Laura Iacuzio, Filippo Civaia, Ciro Canetta, Frederic Berthier, Stephane Rusek, Philippe Rossi, Federico Lombardi, Gilles Dreyfus, Vincent Dor
BACKGROUND: The purpose of the study was to determine the long-term prognostic value of normal adenosine stress cardiac magnetic resonance imaging (CMR) in patients referred for evaluation of myocardial ischemia. METHODS: We reviewed 300 consecutive patients (age 65 ± 11 years, 74% male) with suspected or known coronary disease and normal wall motion who had undergone adenosine stress CMR negative for ischemia and scar. Most patients were at intermediate risk of coronary artery disease...
June 2015: American Heart Journal
Naka Sakamoto, Nobuyuki Sato, Kensuke Oikawa, Ahmed Karim Talib, Eitaro Sugiyama, Akiho Minoshima, Yasuko Tanabe, Toshiharu Takeuchi, Kazumi Akasaka, Yasuaki Saijo, Yuichiro Kawamura, Naoyuki Hasebe
BACKGROUND: The presence of myocardial scar detected by late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) imaging has been described as a good independent predictor of mortality in patients with hypertrophic cardiomyopathy (HCM). Time-domain T-wave alternans (TWA) is also a potential predictor of cardiac mortality in patients with left ventricular dysfunction. OBJECTIVE: The purpose of this study was to elucidate the relationship between LGE distribution and TWA in patients with HCM...
August 2015: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Vineet Goyal, Hilary Bews, Nasir Shaikh, Farrukh Hussain, Davinder S Jassal
BACKGROUND: Left ventricular thrombus (LVT) formation occasionally complicates patient recovery post myocardial infarction, conveying a significant risk of systemic embolism. Accordingly, thrombus detection and subsequent anticoagulation is imperative in order to minimize patient morbidity and mortality. Transthoracic echocardiography (TTE) is the imaging modality most widely used to screen for thrombus formation despite its suboptimal sensitivity and specificity. CASE PRESENTATION: This report describes the discordant imaging findings of a LVT in a 56 year old Caucasian male with an anterior ST elevation myocardial infarction...
2015: BMC Research Notes
Vineet Goyal, Hilary Bews, Nasir Shaikh, Farrukh Hussain, Davinder S Jassal
BACKGROUND: Left ventricular thrombus (LVT) formation occasionally complicates patient recovery post myocardial infarction, conveying a significant risk of systemic embolism. Accordingly, thrombus detection and subsequent anticoagulation is imperative in order to minimize patient morbidity and mortality. Transthoracic echocardiography (TTE) is the imaging modality most widely used to screen for thrombus formation despite its suboptimal sensitivity and specificity. CASE PRESENTATION: This report describes the discordant imaging findings of a LVT in a 56 year old Caucasian male with an anterior ST elevation myocardial infarction...
December 2015: BMC Research Notes
Subhanarayan Panda, Daljeet Kaur, Krishnamohan Lalukota, Gomathi Sundar, Behzad B Pavri, Calambur Narasimhan
BACKGROUND: Ventricular tachycardia (VT), a common manifestation of cardiac sarcoidosis (CS), is associated with high morbidity and mortality. It could be mistaken for idiopathic VT (IVT) in the absence of systemic manifestations and overt cardiac structural abnormality. We studied the electrocardiogram (ECG) characteristics of VT in CS that may distinguish from IVT and also explored the relationship of the ECG characteristics with imaging findings in patients with CS. METHODS AND RESULTS: Twelve-lead ECG characteristics of VT in CS patients (Group I = 37) were compared with IVT (Group II = 49)...
June 2015: Pacing and Clinical Electrophysiology: PACE
Fatma Demirel, Ahmet Adiyaman, Jorik R Timmer, Jan-Henk E Dambrink, Mariël Kok, Willem Jan Boeve, Arif Elvan
OBJECTIVES: We hypothesized that myocardial scar characterization using cardiac magnetic resonance imaging (CMR) may be associated with the occurrence of ventricular tachyarrhythmia (VT), appropriate implantable cardioverter-defibrillator (ICD) therapy and mortality. BACKGROUND: Since a minority of patients with prophylactic ICD implantation receive appropriate ICD therapy, there is a need for more effective risk stratification for primary prevention in patients with ischemic cardiomyopathy...
December 15, 2014: International Journal of Cardiology
Mohamed Abd-Allah Rezk, Mohamed Shawky
OBJECTIVE: To assess the effectiveness of grey-scale and colour Doppler ultrasound (US) versus magnetic resonance imaging (MRI) for the prenatal diagnosis of placenta accreta. METHODS: A prospective observational study including a total of 74 patients with placenta previa and previous uterine scar (n = 74). Grey-scale and colour Doppler US was done followed by MRI by different observers to diagnose adherent placenta. Test validity of US and MRI were calculated...
2016: Journal of Maternal-fetal & Neonatal Medicine
Siok P Lim, Brian A Mc Ardle, Rob S Beanlands, Renee C Hessian
Heart failure presents a significant problem in industrialized countries, with a high prevalence, morbidity, and mortality, where it is most frequently caused by coronary artery disease. Revascularization in patients with symptomatic heart failure has been associated with improved cardiovascular outcomes. Predictors of outcome benefit from revascularization include the presence and extent of hibernating myocardium, ischemia, scar, left ventricular ejection fraction, and renal function. Viability is useful in directing the management of patients with ischemic cardiomyopathy...
September 2014: Seminars in Nuclear Medicine
Deborah H Kwon, Lisa Asamoto, Zoran B Popovic, Kenya Kusunose, Monique Robinson, Milind Desai, Thomas H Marwick, Scott D Flamm
BACKGROUND: Infarct heterogeneity has been shown to be independently associated with adverse outcomes in previous smaller studies. However, it is unknown whether infarct characterization is an independent predictor of all-cause mortality in patients with advanced ischemic cardiomyopathy, after adjusting for clinical risk factors, severity of ischemic mitral regurgitation, incomplete revascularization, and device therapy. METHODS AND RESULTS: A total of 362 patients with ischemic cardiomyopathy (left ventricular dysfunction with >70% stenosis in ≥1 epicardial coronary artery) underwent delayed hyperenhancement-magnetic resonance imaging and coronary angiography between 2002 and 2006...
September 2014: Circulation. Cardiovascular Imaging
João L Cavalcante, Thomas H Marwick, Rory Hachamovitch, Zoran B Popovic, Nael Aldweib, Randall C Starling, Milind Y Desai, Scott D Flamm, Deborah H Kwon
UNLABELLED: Cardiac magnetic resonance (CMR) identifies important prognostic variables in ischemic cardiomyopathy (ICM) patients such as left ventricular (LV) volumes, LV ejection fraction (LVEF), peri-infarct zone, and myocardial scar burden (MSB). It is unknown whether Doppler-based diastolic dysfunction (DDF) retains its prognostic value in ICM patients, in the context of current imaging, medical, and device therapies. METHODS: Diastolic function was evaluated in ICM patients (LVEF ≤ 40% and ≥ 70% stenosis in ≥ 1 coronary artery) who underwent transthoracic echocardiogram and delayed hyperenhancement CMR studies within 7 days...
August 2014: American Heart Journal
Sherelle L Laifer-Narin, Ellie Kwak, Hyonah Kim, Elizabeth M Hecht, Jeffrey H Newhouse
Postpartum and posttermination complications are common causes of morbidity and mortality in women of reproductive age. These complications can be broadly categorized into vascular, infectious, surgical, and neoplastic etiologies, or are due to ectopic implantation of placental or endometrial tissue. Causes of postpartum vascular complications include retained products of conception, arteriovenous malformation, and pseudoaneurysm. Infectious entities include endometritis, abscess, wound cellulitis, and pelvic septic thrombophlebitis...
November 2014: Current Problems in Diagnostic Radiology
Bobak Heydari, Raymond Y Kwong
Despite significant advancements in the treatment of ischemic heart disease (IHD), IHD remains a leading cause of mortality and morbidity. In addition, there remains clinical equipoise regarding a number of important management issues across the spectrum of IHD, from evaluating patients with chest pain in the emergency department, to deciding whether patients with chronic stable angina or severe ischemic cardiomyopathies should undergo invasive revascularization procedures. Recent data over the past 2 decades has demonstrated that cardiac magnetic resonance imaging is highly accurate and carries robust prognostic value in the evaluation of patients with both acute and chronic IHD...
February 2014: Topics in Magnetic Resonance Imaging: TMRI
Divyesh Mahajan, Mandeep Kang, Manavjit Singh Sandhu, Vanita Jain, Naveen Kalra, Niranjan Khandelwal
Cesarean scar pregnancy (CSP) and cesarean scar dehiscence (CSD) are the most dreaded complications of cesarean scar (CS). As the incidence of CS is increasing worldwide, so is the incidence of CSP, especially in cases with assisted reproduction techniques. It is of utmost importance to diagnose CSP in the early first trimester, as it can lead to myometrial rupture with fatal outcome. On the other hand, CSD may be encountered during pregnancy or in the postpartum period. CSD in the postpartum period is very rare and can cause secondary postpartum hemorrhage (PPH) leading to increased maternal morbidity or even death if not diagnosed and managed promptly...
July 2013: Indian Journal of Radiology & Imaging
Mischa T Rijnierse, Stefan de Haan, Hendrik J Harms, Lourens F Robbers, LiNa Wu, Ibrahim Danad, Aernout M Beek, Martijn W Heymans, Albert C van Rossum, Adriaan A Lammertsma, Cornelis P Allaart, Paul Knaapen
BACKGROUND: Risk stratification for ventricular arrhythmias (VAs) is important to refine selection criteria for primary prevention implantable cardioverter defibrillator therapy. Impaired hyperemic myocardial blood flow (MBF) is associated with increased mortality rate in ischemic and nonischemic cardiomyopathy, which may be attributed to electric instability inducing VAs. The aim of this pilot study was to assess whether hyperemic MBF impairment may be related with VA inducibility in patients with ischemic cardiomyopathy...
January 2014: Circulation. Cardiovascular Imaging
Naheed Jivraj, Alkystis Phinikaridou, Ajay M Shah, René M Botnar
Myocardial infarction (MI), and subsequent heart failure, remains a major healthcare problem in the western and developing world and leads to substantial morbidity and mortality. After MI, the ability of the myocardium to recover is closely associated with a complex immune response that often leads to adverse remodeling of the ventricle, and poor prognosis. Currently used clinical imaging modalities allow the assessment of anatomy, perfusion, function, and viability but do not provide insights into specific biological processes...
January 2014: Basic Research in Cardiology
Martin Hadamitzky, Birgit Langhans, Jörg Hausleiter, Carolin Sonne, Robert A Byrne, Julinda Mehilli, Adnan Kastrati, Albert Schömig, Stefan Martinoff, Tareq Ibrahim
BACKGROUND: Infarct size is an important predictor of cardiac risk after acute myocardial infarction. The established modality for its assessment is Tc99m-Sestamibi Single-photon emission computed tomography (SPECT). In recent years, data are emerging demonstrating that scar size as assessed by late gadolinium enhancement in cardiovascular magnetic resonance imaging (CMR) as well as the presence of microvascular obstruction (MO) may also provide prognostic information, however, so far no direct comparisons of both modalities have been reported...
February 2014: European Heart Journal Cardiovascular Imaging
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