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https://www.readbyqxmd.com/read/29778229/a-novel-portable-filtration-system-for-sampling-and-concentration-of-microorganisms-demonstration-on-marine-microalgae-with-subsequent-quantification-using-ic-nasba
#1
Christos-Moritz Loukas, Matthew C Mowlem, Maria-Nefeli Tsaloglou, Nicolas G Green
This paper presents a novel portable sample filtration/concentration system, designed for use on samples of microorganisms with very low cell concentrations and large volumes, such as water-borne parasites, pathogens associated with faecal matter, or toxic phytoplankton. The example application used for demonstration was the in-field collection and concentration of microalgae from seawater samples. This type of organism is responsible for Harmful Algal Blooms (HABs), an example of which is commonly referred to as "red tides", which are typically the result of rapid proliferation and high biomass accumulation of harmful microalgal species in the water column or at the sea surface...
May 2018: Harmful Algae
https://www.readbyqxmd.com/read/29774071/molecular-detection-and-analysis-of-exosomes-using-surface-enhanced-raman-scattering-gold-nanorods-and-a-miniaturized-device
#2
Elyahb Allie Kwizera, Ryan O'Connor, Vojtech Vinduska, Melody Williams, Elizabeth R Butch, Scott E Snyder, Xiang Chen, Xiaohua Huang
Exosomes are a potential source of cancer biomarkers. Probing tumor-derived exosomes can offer a potential non-invasive way to diagnose cancer, assess cancer progression, and monitor treatment responses. Novel molecular methods would facilitate exosome analysis and accelerate basic and clinical exosome research. Methods: A standard gold-coated glass microscopy slide was used to develop a miniaturized affinity-based device to capture exosomes in a target-specific manner with the assistance of low-cost 3-D printing technology...
2018: Theranostics
https://www.readbyqxmd.com/read/29773204/intracerebral-hemorrhage-and-sleep-disordered-breathing
#3
Lynda D Lisabeth, Richard V Scheer, Chengwei Li, Erin Case, Ronald D Chervin, Darin B Zahuranec, Lewis B Morgenstern, Nelda M Garcia, Susan Tower, Devin L Brown
OBJECTIVE/BACKGROUND: Limited data are available on sleep-disordered breathing (SDB) following intracerebral hemorrhage (ICH). Our aim was to characterize the objective measures of post-ICH SDB and questionnaire-reported pre-ICH sleep characteristics, overall and by ethnicity. PATIENTS/METHODS: Participants with ICH who were enrolled in the population-based Brain Attack Surveillance in Corpus Christi project (2010-2016) reported their pre-ICH sleep duration and completed the Berlin Questionnaire to characterize pre-ICH risk of SDB...
June 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29770245/evaluation-of-the-ingval-pedobarography-system-for-monitoring-of-walking-speed
#4
Per Anders Rickard Hellstrom, Anna Åkerberg, Martin Ekström, Mia Folke
Objectives: Walking speed is an important component of movement and is a predictor of health in the elderly. Pedobarography, the study of forces acting between the plantar surface of the foot and a supporting surface, is an approach to estimating walking speed even when no global positioning system signal is available. The developed portable system, Identifying Velocity and Load (IngVaL), is a cost effective alternative to commercially available pedobarography systems because it only uses three force sensing resistors...
April 2018: Healthcare Informatics Research
https://www.readbyqxmd.com/read/29763544/multi-fluorophore-dna-origami-beacon-as-a-biosensing-platform
#5
Denis Selnihhin, Steffen Møller Sparvath, Søren Preus, Victoria Birkedal, Ebbe Sloth Andersen
Biosensors play increasingly important roles in many fields, from clinical diagnosis to environmental monitoring, and there is a growing need for cheap and simple analytical devices. DNA nanotechnology provides methods for the creation of sophisticated biosensors, however many of the developed DNA-based sensors are limited by cumbersome and time-consuming readouts involving advanced experimental techniques. Here we describe design, construction and characterization of an optical DNA origami nano-biosensor device exploiting arrays of precisely positioned organic fluorophores...
May 15, 2018: ACS Nano
https://www.readbyqxmd.com/read/29761993/-design-and-implementation-of-real-time-continuous-glucose-monitoring-instrument
#6
Yonghong Huang, Hongying Liu, Senfu Tian, Ziru Jia, Zi Wang, Xitian Pi
Real-time continuous glucose monitoring can help diabetics to control blood sugar levels within the normal range. However, in the process of practical monitoring, the output of real-time continuous glucose monitoring system is susceptible to glucose sensor and environment noise, which will influence the measurement accuracy of the system. Aiming at this problem, a dual-calibration algorithm for the moving-window double-layer filtering algorithm combined with real-time self-compensation calibration algorithm is proposed in this paper, which can realize the signal drift compensation for current data...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29761985/-design-and-implementation-of-hand-held-electrocardiogram-monitor
#7
Xiaowen Xu, Tianhan Li
A hand-held electrocardiogram (ECG) monitor with capacitive coupling is designed in this study that can rapidly detect ECG signals through clothing. This new device improves many deficiencies of the traditional ECG monitor, such as infection due to direct skin contacting, inconvenience, and time-consuming. In specificity, the hand-held ECG monitor consists of two parts, a sensor and an embedded terminal. ECG signals are initially detected by a sensing electrode placed on the chest through clothing, then treated by single ended differential amplification, filtering and master amplification, and later processed through A/D conversion and ECG signal transmission by CC2540 module...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29757672/enzyme-based-ultrasensitive-electrochemical-biosensors-for-rapid-assessment-of-nitrite-toxicity-recent-advances-and-perspectives
#8
Anjum Gahlaut, Vinita Hooda, Ashish Gothwal, Vikas Hooda
In the present era of rapid international globalization and industrialization, intensive use of nitrite as a fertilizing agent in agriculture, preservative, dyeing agent, food additive and as corrosion inhibitor in industrial sectors is adversely effecting environment, natural habitats and human health. The issue of toxicity and carcinogenicity due to excessive ingestion of nitrites via the dietary intake has led to an imminent need for its efficient real-time monitoring in situ. Nitrite detection employing electrochemical biosensors has been gaining high credibility in the field of clinical research...
May 14, 2018: Critical Reviews in Analytical Chemistry
https://www.readbyqxmd.com/read/29754451/maternal-exercise-season-and-sex-modify-the-human-fetal-circadian-rhythm
#9
Julie Sletten, Germaine Cornelissen, Jørg Assmus, Torvid Kiserud, Susanne Albrechtsen, Jörg Kessler
AIM: The knowledge on circadian rhythmicity is rapidly expanding. We aimed to define the longitudinal development of the circadian heart rate rhythm in the human fetus in an unrestricted, out-of-hospital setting, and to examine the effects of maternal physical activity, season and fetal sex. METHODS: We recruited 48 women with low-risk singleton pregnancies. Using a portable monitor for continuous fetal electrocardiography, fetal heart rate recordings were obtained around gestational weeks 24, 28, 32 and 36...
May 13, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29751442/the-effect-of-portable-hepa-filter-air-cleaners-on-indoor-pm-2-5-concentrations-and-second-hand-tobacco-smoke-exposure-among-pregnant-women-in-ulaanbaatar-mongolia-the-ugaar-randomized-controlled-trial
#10
Prabjit Barn, Enkhjargal Gombojav, Chimedsuren Ochir, Bayarkhuu Laagan, Bolor Beejin, Gerel Naidan, Buyantushig Boldbaatar, Jargalsaikhan Galsuren, Tsogtbaatar Byambaa, Craig Janes, Patricia A Janssen, Bruce P Lanphear, Tim K Takaro, Scott A Venners, Glenys M Webster, Weiran Yuchi, Christopher D Palmer, Patrick J Parsons, Young Man Roh, Ryan W Allen
BACKGROUND: Portable HEPA filter air cleaners can reduce indoor fine particulate matter (PM2.5 ), but their use has not been adequately evaluated in high pollution settings. We assessed air cleaner effectiveness in reducing indoor residential PM2.5 and second hand smoke (SHS) exposures among non-smoking pregnant women in Ulaanbaatar, Mongolia. METHODS: We randomized 540 participants to an intervention group receiving 1 or 2 HEPA filter air cleaners or a control group receiving no air cleaners...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29743607/development-of-a-lab-on-a-chip-method-for-rapid-assay-of-xylella-fastidiosa-subsp-pauca-strain-codiro
#11
Maria Serena Chiriacò, Andrea Luvisi, Elisabetta Primiceri, Erika Sabella, Luigi De Bellis, Giuseppe Maruccio
Xylella fastidiosa subsp. pauca strain CoDiRO, a pathogen responsible for Olive Quick Decline Syndrome (OQDS), is strongly threatening the agricultural-based economy of South Italy and making its typical landscape collapse. The bacteria can also infect more than other twenty woody or shrub species and quarantine programs are carried out in Italy. Since symptoms of OQDS like leaf scorching and wilting of canopy may appear several months after infection and some hosts are asymptomatic, a tool for the rapid and early screening of plants is desirable, in order to plan a sudden control strategy and apply programs for pest management...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29738487/application-of-a-portable-multi-analyte-biosensor-for-organic-acid-determination-in-silage
#12
Johanna Pilas, Yasemen Yazici, Thorsten Selmer, Michael Keusgen, Michael J Schöning
Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days...
May 8, 2018: Sensors
https://www.readbyqxmd.com/read/29736505/multiplexed-microfluidic-fluorescence-immunoassay-with-photodiode-array-signal-acquisition-for-sub-minute-and-point-of-need-detection-of-mycotoxins
#13
Ruben R G Soares, Denis R Santos, Inês F Pinto, Ana M Azevedo, M Raquel Aires-Barros, Virginia Chu, João P Conde
Portable, rapid, cost effective and simple analytical tools are in increasing demand to facilitate the routine monitoring of target chemical/biological compounds at the point-of-need. Such devices are highly relevant within the context of food safety, particularly concerning the screening of highly toxic and strictly regulated mycotoxins. To achieve ultrarapid detection of mycotoxins, namely aflatoxin B1, ochratoxin A and deoxynivalenol, at the point-of-need, a novel multiplexed bead-based microfluidic competitive immunosensor, coupled with an array of a-Si:H thin-film photodiodes for integrated fluorescence signal acquisition, is reported...
May 8, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29735689/wireless-intraoral-hybrid-electronics-for-real-time-quantification-of-sodium-intake-toward-hypertension-management
#14
Yongkuk Lee, Connor Howe, Saswat Mishra, Dong Sup Lee, Musa Mahmood, Matthew Piper, Youngbin Kim, Katie Tieu, Hun-Soo Byun, James P Coffey, Mahdis Shayan, Youngjae Chun, Richard M Costanzo, Woon-Hong Yeo
Recent wearable devices offer portable monitoring of biopotentials, heart rate, or physical activity, allowing for active management of human health and wellness. Such systems can be inserted in the oral cavity for measuring food intake in regard to controlling eating behavior, directly related to diseases such as hypertension, diabetes, and obesity. However, existing devices using plastic circuit boards and rigid sensors are not ideal for oral insertion. A user-comfortable system for the oral cavity requires an ultrathin, low-profile, and soft electronic platform along with miniaturized sensors...
May 7, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29730934/development-of-an-integrated-syringe-pump-based-environmental-water-analyzer-isea-and-application-of-it-for-fully-automated-real-time-determination-of-ammonium-in-fresh-waters
#15
Jian Ma, Peicong Li, Zhaoying Chen, Kunning Lin, Nengwang Chen, Yiyong Jiang, Jinxin Chen, Bangqin Huang, Dongxing Yuan
Development of a multipurpose integrated syringe-pump-based environmental-water analyzer (iSEA) and its application for spectrophotometric determination of ammonium is presented. The iSEA consisted a mini-syringe pump equipped with a selection valve and laboratory-programmed software written by LabVIEW. The chemistry is based on a modified indophenol method using o-phenylphenol. The effect of reagent concentrations and sample temperatures were evaluated. This fully automated analyzer had a detection limit of 0...
May 6, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29730553/exploration-of-solvent-responsive-cr-3-schiff-base-conjugates-formonitoring-cr-3-ions-and-organophosphates-fabrication-of-spot-testingdevices
#16
Jaswant Singh, Varinder Kaur, Raghubir Singh, Vimal K Bhardwaj
Herein, we report 2-((2-hydroxybenzylidene)hydrazono)(phenyl)methyl)-5-methoxyphenol (SB) synthesized by Schiff base condensation and characterized by spectroscopic techniques, elemental analysis and X-ray crystallography. In solution phase, it interacts with Cr3+ ions and exhibits a prominent fluorimetric switch due to the formation of SB·Cr3+ conjugate. The dual behavior of SB·Cr3+ conjugates i.e. self-aggregation in high water fraction (fw  > 50%) and dissolution in low water fraction (fw  < 50%) proves this conjugation excellent tool for monitoring Cr3+ ions...
April 27, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29730488/the-use-of-wearable-devices-for-walking-and-running-gait-analysis-outside-of-the-lab-a-systematic-review
#17
REVIEW
Lauren C Benson, Christian A Clermont, Eva Bošnjak, Reed Ferber
BACKGROUND: Quantitative gait analysis is essential for evaluating walking and running patterns for markers of pathology, injury, or other gait characteristics. It is expected that the portability, affordability, and applicability of wearable devices to many different populations will have contributed advancements in understanding the real-world gait patterns of walkers and runners. Therefore, the purpose of this systematic review was to identify how wearable devices are being used for gait analysis in out-of-lab settings...
May 1, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29729482/perkapp-a-general-purpose-persuasion-architecture-for-healthy-lifestyles
#18
Rosa Maimone, Marco Guerini, Mauro Dragoni, Tania Bailoni, Claudio Eccher
Automatically monitoring and supporting healthy lifestyle is a recent research trend, fostered by the availability of low-cost monitoring devices, and it can significantly contribute to the prevention of chronic diseases deriving from incorrect diet and lack of physical activity. In this paper, we present a general purpose architecture for persuasion scenarios and behavioral change. The architecture is designed to be easily portable across languages and domains and has been implemented and evaluated in a specific system for Workplace Health Promotion (WHP) called PerKApp...
May 2, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29726443/towards-designing-a-secure-exchange-platform-for-diabetes-monitoring-and-therapy
#19
Jan-Patrick Weiß, Tobias Welzel, Bernd J Hartmann, Ursula Hübner, Frank Teuteberg
BACKGROUND: Diabetes mellitus is one of the most prominent examples of chronic conditions that requires an active patient self-management and a network of specialists. OBJECTIVES: The aim of this study was to analyze the user and legal requirements and develop a rough technology concept for a secure and patient-centered exchange platform. METHODS: To this end, 14 experts representing different stakeholders were interviewed and took part in group discussions at three workshops, the pertinent literature and legal texts were analyzed...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29726127/thermal-imaging-as-a-tool-for-evaluating-tumor-treatment-efficacy
#20
Oshrit A Hoffer, Merav A Ben-David, Eyal Katz, Dana Zoltnik Kirshenabum, Dror Alezra, Yair Zimmer, Itzhak Kelson, Israel Gannot
Breast cancer is the most frequently diagnosed cancer among women in the Western world. Thermography is a nonionizing, noninvasive, portable, and low-cost method that can be used in an outpatient clinic. It was tried as a tool to detect breast cancer tumors, however, it had too many false readings. Thermography has been extensively studied as a breast cancer detection tool but was not used as a treatment monitoring tool. The purpose of this study was to investigate the possibility of using thermal imaging as a feedback system to optimize radiation therapy...
May 2018: Journal of Biomedical Optics
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