keyword
MENU ▼
Read by QxMD icon Read
search

Breast spectroscopy

keyword
https://www.readbyqxmd.com/read/29227197/moderating-factors-in-tissue-tonometry-and-bioimpedance-spectroscopy-measures-in-the-lower-extremity-of-healthy-young-people-in-australia-and-myanmar
#1
Janet Douglass, Patricia Graves, Susan Gordon
BACKGROUND: Expected values for tissue tonometry and bioimpedance spectroscopy (BIS) in the lower extremity of young people have not been established. These measures are commonly used to assess tissue changes in adult, breast cancer-related lymphedema of the arm. In tropical regions, identification of tissue changes in the lower limbs related to lymphatic filariasis is required; hence expected values and factors contributing to variation in tissue tonometry and BIS in two tropical populations were investigated...
December 11, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/29223048/extraction-protocol-and-liquid-chromatography-tandem-mass-spectrometry-method-for-determining-micelle-entrapped-paclitaxel-at-the-cellular-and-subcellular-levels-application-to-a-cellular-uptake-and-distribution-study
#2
Nan Zheng, Bin Lian, Wenwen Du, Guobing Xu, Jiafu Ji
Paclitaxel-loaded polymeric micelles (PTX-PM) are commonly used as tumor-targeted nanocarriers and display outstanding antitumor features in clinic, but its accumulation and distribution in vitro are lack of investigation. It is probably due to the complex micellar system and its low concentration at the cellular or subcellular levels. In this study, we developed an improved extraction method, which was a combination of mechanical disruption and liquid-liquid extraction (LLE), to extract the total PTX from micelles in the cell lysate and subcellular compartments...
December 6, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29214243/intracellular-investigation-on-the-differential-effects-of-4-polyphenols-on-mcf-7-breast-cancer-cells-by-raman-imaging
#3
A Mignolet, B R Wood, E Goormaghtigh
The past decades have seen significant interest in the study of polyphenolic compounds as potential therapeutic agents in medicine because they display a vast array of cellular effects beneficial to treat or manage a plethora of chronic diseases including inflammatory diseases, cardiovascular abnormalities and several types of cancer. These compounds act at different stages of carcinogenesis but deciphering their mode of action is a complex task. Live MCF-7 breast cancer cells were investigated using Raman imaging to evaluate the perturbations induced after incubating cells with four different polyphenols: EGCG, gallic acid, resveratrol and tannic acid...
December 7, 2017: Analyst
https://www.readbyqxmd.com/read/29209407/heavy-metals-effect-on-breast-cancer-progression
#4
А Romaniuk, M Lyndin, V Sikora, Y Lyndina, S Romaniuk, K Sikora
Background: Breast cancer is the most frequent localization of malignant process in American women and women of European countries. To date it is not possible to control the morbidity growth due to lack of effective ways of primary prevention. Comparing the incidence of breast cancer in developed countries with the countries of Asia and Africa, there is the fact of population predominance lesion in more urbanized countries. This suggests that the environment along with other factors, occupies a significant place in the initiation and progression of breast neoplasia...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/29206323/impact-of-intratumoral-heterogeneity-of-breast-cancer-tissue-on-quantitative-metabolomics-using-high-resolution-magic-angle-spinning-1-h-nmr-spectroscopy
#5
Mikheil Gogiashvili, Salome Horsch, Rosemarie Marchan, Kathrin Gianmoena, Cristina Cadenas, Berno Tanner, Sabrina Naumann, Diana Ersova, Frank Lippek, Jörg Rahnenführer, Jan T Andersson, Roland Hergenröder, Jörg Lambert, Jan G Hengstler, Karolina Edlund
High-resolution magic angle spinning (HR MAS) nuclear magnetic resonance (NMR) spectroscopy is increasingly being used to study metabolite levels in human breast cancer tissue, assessing, for instance, correlations with prognostic factors, survival outcome or therapeutic response. However, the impact of intratumoral heterogeneity on metabolite levels in breast tumor tissue has not been studied comprehensively. More specifically, when biopsy material is analyzed, it remains questionable whether one biopsy is representative of the entire tumor...
December 5, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/29202332/chloro-triphenylphosphine-gold-i-a-forefront-reagent-in-gold-chemistry-as-apoptotic-agent-for-cancer-cells
#6
M P Chrysouli, C N Banti, N Kourkoumelis, N Panayiotou, G S Markopoulos, A J Tasiopoulos, S K Hadjikakou
The antiproliferative activity of the gold complex [Au(tpp)Cl] (1) (tpp=triphenyphosphine) against human breast adenocarcinoma cells (MCF-7) and normal human fetal lung fibroblast cells (MRC-5) was investigated. The compound exhibits stronger activity against MCF-7 cells than cisplatin. The apoptotic pathway, especially though the mitochondrion damage was concluded by cell cycle arrest, flow cytometry using Annexin V-Fluorescein IsoThioCyanate (FITC) and Propidium Iodide (PI) as indicators, assays and permeabilization of the mitochondrial membrane tests...
November 8, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29201104/biosynthesis-characterization-antimicrobial-and-cytotoxic-effects-of-silver-nanoparticles-using-nigella-arvensis-seed-extract
#7
Azam Chahardoli, Naser Karimi, Ali Fattahi
The biogenic synthesis of metal nanomaterial offers an environmentally benign alternative to the traditional chemical synthesis routes. In the present study, the green synthesis of silver nanoparticles (AgNPs) from aqueous solution of silver nitrate (AgNO3) by using Nigella arvensis L. seed powder extract (NSPE) has been reported. AgNPs were characterized by UV-vis absorption spectroscopy with an intense surface plasmon resonance band at 435 nm which reveals the formation of nanoparticles. Fourier transmission infrared spectroscopy (FTIR) showed that nanoparticles were capped with plant compounds...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29200845/solid-lipid-nanoparticles-for-thermoresponsive-targeting-evidence-from-spectrophotometry-electrochemical-and-cytotoxicity-studies
#8
Mubashar Rehman, Ayesha Ihsan, Asadullah Madni, Sadia Zafar Bajwa, Di Shi, Thomas J Webster, Waheed S Khan
Thermoresponsive drug delivery systems are designed for the controlled and targeted release of therapeutic payload. These systems exploit hyperthermic temperatures (>39°C), which may be applied by some external means or due to an encountered symptom in inflammatory diseases such as cancer and arthritis. The objective of this paper was to provide some solid evidence in support of the hypothesis that solid lipid nanoparticles (SLNs) can be used for thermoresponsive targeting by undergoing solid-liquid phase transition at their melting point (MP)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29199558/identification-and-evaluation-of-bioactivity-of-compounds-from-the-mushroom-pleurotus-nebrodensis-agaricomycetes-against-breast-cancer
#9
Jingfeng Hao, Xueya Zhang, Wancong Yu, Ru Wang, Zhaohui Xue, Xiaohong Kou
Breast cancer affects millions of women annually worldwide and is the leading cause of cancer death in women. Various bioactive phytochemicals based on natural products are considered to be an important source of chemopreventive agents. In this study we report-to our knowledge for the first time-9 phytochemicals isolated by nuclear magnetic resonance spectroscopy and mass spectrometry from the acetic ether extract of Pleurotus nebrodensis and identified as (1) ergosterol, (2) uracil, (3) ergosterol-3-O-β-D-glucopyranoside, (4) cerevisterol, (5) cerebroside B, (6) 5'-methylthioadenosine, (7) adenosine, (8) hypoxanthine, and (9) uridine...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29195215/amberlite-ir-120-h-mediated-on-water-synthesis-of-fluorescent-ruthenium-ii-arene-8-hydroxyquinoline-complexes-for-cancer-therapy-and-live-cell-imaging
#10
Ashaparna Mondal, Sourav De, Santanu Maiti, Bidisha Sarkar, Ashok Kumar Sk, Rini Jacob, Anbalagan Moorthy, Priyankar Paira
A series of Ruthenium-Quinolinol complexes (3a-d &4a-d) has been synthesized by employing a simple, efficient and environmental friendly condition. Catalytic role of Amberlite IRA-120(H) has been demonstrated. The structures of the new compounds were elucidated by the analysis of spectroscopic data. The stability of these complexes was measured by UV spectroscopy & time dependent NMR spectroscopy. These newly developed complexes were represented as potential anticancer agent against human breast carcinoma cell line (MCF-7), human Epitheloid Cervix Carcinoma (HeLa), human lung adenocarcinoma epithelial cell line (A549) and human colon cancer cell line (Caco-2)...
November 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29187481/pre-surgical-multiparametric-assessment-of-breast-lesions-using-3-tesla-magnetic-resonance
#11
Hynek Mirka, Radek Tupy, Andrea Narsanska, Ondrej Hes, Jiri Ferda
BACKGROUND/AIM: The aim of this study was to evaluate experience with multiparametric breast imaging on 3-Tesla magnetic resonance (3T-MRI) scanner using a dedicated 18-channel coil compared to histological findings in women after surgery. MATERIALS AND METHODS: The study included 100 women with 105 Breast Imaging Reporting and Data System (BI-RADS) 4 to 6 lesions by mammography who were examined using 3T-MRI and subsequently underwent surgery. MRI included non-contrast T1, T2 and T2 short tau inversion recovery (STIR) sequences, diffusion-weighted imaging with apparent diffusion coeficient maps, postcontrast dynamic study and single-voxel MRI spectroscopy...
December 2017: Anticancer Research
https://www.readbyqxmd.com/read/29186208/cytotoxic-effect-of-albumin-coated-copper-nanoparticle-on-human-breast-cancer-cells-of-mda-mb-231
#12
Marzieh Azizi, Hedayatollah Ghourchian, Fatemeh Yazdian, Fariba Dashtestani, Hojjat AlizadehZeinabad
PURPOSE: The aim of this study was to design a new nanocomposite that would have high cytotoxicity against invasive breast cancer cells and minimum side effects on normal cells. METHODS: An albumin nano-carrier for delivery of CuNPs was developed. The ACuNPs formation was characterized by TEM, DLS and UV-Vis, fluorescence and circular dichroism spectroscopy. The cytotoxic efficacy of the ACuNPs against human breast cancer cells (MDA-MB 231) and normal cells (MCF-10A) was compared using a standard MTT assay...
2017: PloS One
https://www.readbyqxmd.com/read/29182515/sesquiterpenes-from-the-saudi-red-sea-litophyton-arboreum-with-their-cytotoxic-and-antimicrobial-activities
#13
Lamia T Abou El-Kassem, Usama W Hawas, Samy K El-Desouky, Radwan Al-Farawati
A new pseudoguaiane-type sesquiterpene named litopharbol (1) was isolated from the methanolic extract of the Red Sea soft coral Litophyton arboreum, along with known sesquiterpenoids alismol (2), alismorientol B (3), teuhetenone A (4), and calamusin I (5); steroid, 24-methyl-cholesta-5,24(28)-diene-3β-ol (6), alkyl glyceryl ether, chimyl alcohol (7); sphingolipid, erythro-N-dodecanoyl-docosasphinga-(4E,8E)-dienine (8); and nitrogenous bases, thymine (9) and thymidine (10). The structures were determined on the basis of nuclear magnetic resonance (NMR) spectroscopic (1D and 2D NMR data including heteronuclear single quantum coherence spectroscopy, heteronuclear multiple-bond correlation spectroscopy, and nuclear Overhauser effect spectroscopy) and mass spectrometric analyses...
November 28, 2017: Zeitschrift Für Naturforschung. C, A Journal of Biosciences
https://www.readbyqxmd.com/read/29180051/aptamer-based-assay-of-plated-derived-grow-factor-in-unprocessed-human-plasma-sample-and-mcf-7-breast-cancer-cell-lysates-using-gold-nanoparticle-supported-%C3%AE-cyclodextrin
#14
Mohammad Hasanzadeh, Nasrin Razmi, Ahad Mokhtarzadeh, Nasrin Shadjou, Soltanali Mahboob
Platelet-derived growth factor (PDGF), a protein biomarker, is directly involved in many cell transformation processes, such as tumor growth and progression. Elevation platelet-derived growth factor (PDGF-BB) concentration in plasma could indicate the accelerating growth of metastatic breast tumors and angiogenesis. The development of an apta-assay for detection of PDGF-BB in is presented in this work. A highly specific DNA-aptamer, selected to PDGF-BB was immobilized onto a gold nanoparticles supported α-cyclodextrin and electrochemical measurements were performed in a solution containing the phosphate buffer solution with physiological pH...
November 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29172457/characterizing-deformability-and-electrical-impedance-of-cancer-cells-in-a-microfluidic-device
#15
Ying Zhou, Dahou Yang, Yinning Zhou, Bee Luan Khoo, Jongyoon Han, Ye Ai
Mechanical properties of cells, reflective of various biochemical characteristics such as gene expression and cytoskeleton, are promising label-free biomarkers for studying and characterizing cells. Electrical properties of cells, dependent on the cellular structure and content, are also label-free indicators of cell states and phenotype. In this work, we have developed a microfluidic device that is able to simultaneously characterize the mechanical and electrical properties of individual biological cells in a high-throughput manner (> 1,000 cells/min)...
November 27, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29164209/tuning-the-cytotoxicity-of-ruthenium-ii-para-cymene-complexes-by-mono-substitution-at-a-triphenylphosphine-phenoxydiphenylphosphine-ligand
#16
Lorenzo Biancalana, Stefano Zacchini, Nicola Ferri, Maria Giovanna Lupo, Guido Pampaloni, Fabio Marchetti
The new complexes [RuCl2(η(6)-p-cymene)(κP-Ph2PR)] [R = 4-C6H4OSiMe2(t)Bu, 1; R = 4-C6H4Br, 2; R = OC([double bond, length as m-dash]O)CHCl2, 3; R = OPh, 4; R = O(2-C6H4SiMe2(t)Bu), 5] and [Ru(C2O4)(η(6)-p-cymene){κP-Ph2PO(2-C6H4(SiMe2(t)Bu))}], 6, were obtained in 83-98% yield from Ru(ii) arene precursors by three different synthetic strategies. The unprecedented phosphine Ph2P(O(2-C6H4SiMe2(t)Bu)) was synthesized in 86% yield from 2-C6H4Br(OSiMe2(t)Bu) and Ph2PCl, via intramolecular oxygen to carbon 1,3 migration of the silyl group (retro-Brook rearrangement)...
November 22, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29160836/an-in-vitro-study-of-the-photodynamic-effectiveness-of-go-ag-nanocomposites-against-human-breast-cancer-cells
#17
Fozia Shaheen, Muhammad Hammad Aziz, Muhammad Fakhar-E-Alam, Muhammad Atif, Mahvish Fatima, Riaz Ahmad, Atif Hanif, Saqib Anwar, Fatima Zafar, Ghazanfar Abbas, Syed Mansoor Ali, Mukhtar Ahmed
Graphene-based materials have garnered significant attention because of their versatile bioapplications and extraordinary properties. Graphene oxide (GO) is an extremely oxidized form of graphene accompanied by the functional groups of oxygen on its surface. GO is an outstanding platform on which to pacify silver nanoparticles (Ag NPs), which gives rise to the graphene oxide-silver nanoparticle (GO-Ag) nanocomposite. In this experimental study, the toxicity of graphene oxide-silver (GO-Ag) nanocomposites was assessed in an in vitro human breast cancer model to optimize the parameters of photodynamic therapy...
November 21, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29155396/biomimetic-synthesis-of-silver-nanoparticles-from-streptomyces-atrovirens-and-their-potential-anticancer-activity-against-human-breast-cancer-cells
#18
Ramasamy Subbaiya, Muthupandian Saravanan, Andavar Raja Priya, Konathala Ravi Shankar, Masilamani Selvam, Muhammad Ovais, Ramachandran Balajee, Hamed Barabadi
Silver nanoparticles (AgNPs) have been undeniable for its antimicrobial activity while its antitumour potential is still limited. Therefore, the present study focused on determining cytotoxic effects of AgNPs on Michigan cancer foundation-7 (MCF-7) breast cancer cells and its corresponding mechanism of cell death. Herein, the authors developed a bio-reduction method for AgNPs synthesis using actinomycetes isolated from marine soil sample. The isolated strain was identified by 16s ribotyping method and it was found to be Streptomyces atrovirens...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29151985/synthesis-and-anticancer-evaluation-of-some-new-3-benzyl-4-8-dimethylbenzopyrone-derivatives
#19
Sohair L El-Ansary, Doaa E Abdel Rahman, Lina M A Abdel Ghany
Introduction: New benzopyrone derivatives such as Schiff's like compounds, acetohydrazides or substituted with oxadiazole or pyrazole heterocycles were synthesized from parent acid hydrazide compound 3. Methods and Materials: Structures of the synthesized compounds were elucidated using IR, NMR and mass spectroscopy. All the synthesized derivatives were selected by National Cancer Institute (NCI), Bethesda, and evaluated for their in vitro anticancer activity in the full NCI 60 cell lines panel assay...
2017: Open Medicinal Chemistry Journal
https://www.readbyqxmd.com/read/29144424/synthesis-characterization-and-biological-activities-of-biopolymeric-schiff-bases-prepared-with-chitosan-and-salicylaldehydes-and-their-pd-ii-and-pt-ii-complexes
#20
Hellen Franciane Gonçalves Barbosa, Maha Attjioui, Ana Paula Garcia Ferreira, Edward Ralph Dockal, Nour Eddine El Gueddari, Bruno M Moerschbacher, Éder Tadeu Gomes Cavalheiro
In an attempt to enhance chitosan biological activities, biopolymeric Schiff bases of chitosan and different salicylaldehydes and their palladium(II) and platinum(II) complexes were synthesized and tested. The chemical structures of these derivatives were characterized using ¹H-NMR, FTIR spectroscopy and XPRD. Thermal analysis was done through TGA/DTG-DTA. Electronic absorption spectra and surface morphologies were analyzed by SEM-EDAX. Chitosan and its derivatives were evaluated for their in vitro antimicrobial activity against two common bacterial and fungal plant pathogens Pseudomonas syringae pv...
November 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
keyword
keyword
57880
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"