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https://www.readbyqxmd.com/read/29468768/evaluation-of-a-realistic-cleansing-protocol-for-preventing-discoloration-of-denture-resins
#1
Panagiotis Zoidis, Nikolaos Polychronakis, Panagiotis Lagouvardos, Gregory Polyzois, Hien Chi Ngo
PURPOSE: To evaluate the efficacy of a realistic staining/cleansing protocol for long-term prevention of discoloration of denture base resins. MATERIALS AND METHODS: Sixty discs (20 × 2.5 mm) of auto- and heat-polymerizing denture acrylic resins were fabricated following manufacturer's instructions, polished on one side and stored in water (37°C) for 24 hours before they were assigned randomly into 6 groups (3 for each material, n = 10) to receive 220 cycles of three immersion protocols...
February 22, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29467928/inferring-modes-of-evolution-from-colorectal-cancer-with-residual-polyp-of-origin
#2
Minsoo Kim, Brooke R Druliner, Nikolaos Vasmatzis, Taejeong Bae, Nicholas Chia, Alexej Abyzov, Lisa A Boardman
Besides the classical evolutionary model of colorectal cancer (CRC) defined by the stepwise accumulation of mutations in which normal epithelium transforms through an intermediary polyp stage to cancer, a few studies have proposed alternative modes of evolution (MOE): early eruptive subclonal expansion, branching of the subclones in parallel evolution, and neutral evolution. However, frequencies of MOEs and their connection to mutational characteristics of cancer remain elusive. In this study, we analyzed patterns of somatic single nucleotide variations (SNVs) and copy number aberrations (CNAs) in CRC with residual polyp of origin from 13 patients in order to determine this relationship...
January 23, 2018: Oncotarget
https://www.readbyqxmd.com/read/29465989/correction-to-design-rule-for-improved-open-circuit-voltage-in-binary-and-ternary-organic-solar-cells
#3
Nikolaos Felekidis, Armantas Melianas, Martijn Kemerink
No abstract text is available yet for this article.
February 21, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29465628/long-term-clinical-and-computed-tomography-angiographic-follow-up-after-totally-endoscopic-coronary-artery-bypass-grafting
#4
Lukas Stastny, Markus Kofler, Julia Dumfarth, Alim Basaran, Dominik Wiedemann, Thomas Schachner, Gudrun Feuchtner, Johannes Bonatti, Nikolaos Bonaros
OBJECTIVE: Totally endoscopic coronary artery bypass grafting was shown to be feasible and safe, with excellent clinical and angiographic mid-term results. Data on long-term outcome are lacking. Therefore, we aimed to investigate the long-term rate of major adverse cardiac and cerebrovascular events and left internal mammary artery patency rate in patients undergoing arrested heart totally endoscopic coronary artery bypass grafting. METHODS: From 2001 to 2012, a total of 208 arrested heart-totally endoscopic coronary artery bypass grafting patients were prospectively included...
February 21, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29465258/administration-of-low-molecular-weight-heparin-in-patients-with-two-or-more-unsuccessful-ivf-icsi-cycles-a-multicenter-cohort-study
#5
Charalampos Siristatidis, Konstantinos Dafopoulos, George Salamalekis, George Galazios, Nikolaos Christoforidis, Theodoros Moustakarias, Nikoleta Koutlaki, Constantinos Bouschanetzis, Dimitrios Loutradis, Petros Drakakis
To compare the effects of the administration of low-molecular-weight heparin (LMWH) in subfertile patients with two or more unsuccessful IVF/ICSI cycles. In this six-center two-arm retrospective cohort study, the study population (230 women) underwent a GnRH-antagonist protocol and was classified into two groups, according to the couse of LMWH or not. Groups were compared regarding the clinical and IVF/ICSI cycle characteristics and reproductive outcomes, whereas clinical pregnancy and miscarriage constituted the primary endpoints...
February 21, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29462109/effects-of-the-active-constituents-of-crocus-sativus-l-crocins-and-their-combination-with-memantine-on-recognition-memory-in-rats
#6
Nikolaos Pitsikas, Petros A Tarantilis
Crocus sativus L., is a plant cultivated in many countries of the world. Crocins are among the active constituents of C. sativus and their implication in cognition has been proposed. The present study was designed to investigate in the rat the effects of crocins on distinct recognition memory components (encoding, storage and retrieval). Subsequently, the potential use of crocins as adjunctive agents for the treatment of memory disorders was examined. Thus, the effects exerted by a combination of subthreshold doses of crocins and memantine on recognition memory were evaluated...
February 16, 2018: Behavioural Pharmacology
https://www.readbyqxmd.com/read/29460717/strain-specific-differences-in-the-effects-of-lymphocytes-on-the-development-of-insulin-resistance-and-obesity-in-mice
#7
Elisavet Kodela, Maria Moysidou, Sevasti Karaliota, Yassemi Koutmani, Panagiotis Tsakanikas, Konstantia Kodella, Eleni A Karavia, Kyriakos E Kypreos, Nikolaos Kostomitsopoulos, Katia P Karalis
Obesity is characterized as a chronic, low-grade inflammatory disease owing to the infiltration of the adipose tissue by macrophages. Although the role of macrophages in this process is well established, the role of lymphocytes in the development of obesity and metabolism remains less well defined. In the current study, we fed WT and Rag1-/- male mice, of C57BL/6J and BALB/c backgrounds, high-fat diet (HFD) or normal diet for 15 wk. Compared with WT mice, Rag1-/- mice of either of the examined strains were found less prone to insulin resistance after HFD, had higher metabolic rates, and used lipids more efficiently, as shown by the increased expression of genes related to fatty acid oxidation in epidydimal white adipose tissue...
February 1, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29459992/a-systematic-classification-of-the-vertebral-artery-variable-origin-clinical-and-surgical-implications
#8
REVIEW
Nikolaos Lazaridis, Maria Piagkou, Marios Loukas, Evangelia-Theophano Piperaki, Trifon Totlis, Georgios Noussios, Konstantinos Natsis
Several congenital anomalies regarding the right (RVA) and left (LVA) vertebral artery have been described. The current paper aims to perform a systematic literature review of the variable vertebral artery (VA) origin from the aortic arch (AOA) and its branches. The incidence of these variants and the ensuing AOA branching pattern are highlighted. Atypical origin cases were found more commonly unilaterally, while LVA presented the majority of the aberrancies. The LVA emersion from the AOA (3.6%) and the RVA from the right common carotid artery (RCCA) (0...
February 19, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29458398/phlebotomine-sand-flies-diptera-psychodidae-in-the-greek-aegean-islands-ecological-approaches
#9
Nikolaos Tsirigotakis, Christoforos Pavlou, Vasiliki Christodoulou, Emmanouil Dokianakis, Christos Kourouniotis, Bulent Alten, Maria Antoniou
BACKGROUND: Blood-sucking phlebotomine sand flies are the vectors of the protozoan parasites Leishmania spp. Different Phlebotomus species transmit different Leishmania species causing leishmaniases which are neglected diseases emerging/reemerging in new regions. Thirteen sand fly species, ten belonging to the medically important genus Phlebotomus and three belonging to Sergentomyia are known in Greece. An increasing number of human and dog cases are reported each year from all parts of the country including the Aegean Islands...
February 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29456484/7q-deletion-12q-duplication-is-the-possible-cause-of-an-alobar-holoprosencephaly-case
#10
Vassilis Paspaliaris, Nikolaos Vrachnis, Zoe Iliodromiti, Nikolaos Antonakopoulos, Giorgos Papaioannou, Nikolaos Vlachadis, Foteini Anastasiadou, Sotirios Sotiriou, Antonios Garas, Lorreta Thomaidis, Emmanouil Manolakos
Holoprosencephaly (HPE) spectrum disorder is the most common congenital malformation of the human brain with absence of or incomplete midline cleavage. Its cause is heterogenic, making genetic counseling a challenge. In this case report, a pregnancy affected by alobar HPE is described. Using aCGH, an 8.9-Mb deletion at 7q36.1q36.3 together with a 4.9-Mb duplication at 12q24.32q24.33 is assumed to be the possible reason for this alobar HPE case. It is discussed that disruption of key elements of the developing brain, taking environmental factors into account, contributes to the HPE spectrum...
December 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/29456040/a-very-rare-case-of-renal-cell-carcinoma-metastasis-to-spermatic-cord-and-a-condensed-literature-review
#11
Ioannis Tsouknidas, Nikolaos Tasis, Charalambos Kokkinos, Helen Trihia, Dimitrios Filippou, Panagiotis Skandalakis, Theodoros Troupis
INTRODUCTION: Renal cell carcinoma (RCC) is proved to be the ninth most common malignancy. Two-third of the patients suffering from RCC will present metastases. Secondary metastases of RCC to spermatic cord are very rare. PRESENTATION OF CASE: In this report we present the case of a patient with renal cell carcinoma with metachronous metastasis to the spermatic cord occurring two years after the initial diagnosis of the disease. DISCUSSION: Our patient was treated according to EAU guidelines...
December 26, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29455829/caught-in-the-act-massive-pulmonary-thrombus-crossing-a-patent-foramen-ovale
#12
Alexandros Kallifatidis, Christos Tourmousoglou, Gerasimos Gogas, Nikolaos Nikoloudakis, Antonis Pitsis
No abstract text is available yet for this article.
March 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455293/variations-of-transverse-foramina-in-cervical-vertebrae-what-happens-to-the-vertebral-artery
#13
Aristeidis Zibis, Vasileios Mitrousias, Nikolaos Galanakis, Nikoletta Chalampalaki, Dimitrios Arvanitis, Apostolos Karantanas
PURPOSE: The purpose of this study is to examine variations of the foramen transversarium and the vertebral artery in computed tomography angiographies (CTa) of the cervical spine, investigate their coexistence, and present possible considerations regarding such variations in spine surgical procedures. METHODS: Fifty CTa of the neck were retrospectively reviewed. Transverse and anteroposterior diameter of the foramen and diameter of the vertebral artery were measured...
February 17, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29455169/positron-emission-tomography-pet-for-prediction-of-glioma-histology-protocol-for-an-individual-level-data-meta-analysis-of-test-performance
#14
Nikolaos A Trikalinos, Takashi Nihashi, Evangelos Evangelou, Teruhiko Terasawa
INTRODUCTION: Gliomas, the most commonly diagnosed primary brain tumours, are associated with varied survivals based, in part, on their histological subtype. Therefore, accurate pretreatment tumour grading is essential for patient care and clinical trial design. METHODS AND ANALYSIS: We will perform an individual-level data meta-analysis of published studies to evaluate the ability of different types of positron emission tomography (PET) to differentiate high from low-grade gliomas...
February 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29454363/identification-of-wild-caught-phlebotomine-sand-flies-from-crete-and-cyprus-using-dna-barcoding
#15
Emmanouil Dokianakis, Nikolaos Tsirigotakis, Vasiliki Christodoulou, Nikos Poulakakis, Maria Antoniou
BACKGROUND: Phlebotomine sand flies (Diptera: Psychodidae) are vectors of Leishmania spp., protozoan parasites responsible for a group of neglected diseases called leishmaniases. Two sand fly genera, Phlebotomus and Sergentomyia, contain species that are present in the Mediterranean islands of Crete and Cyprus where the visceral (VL), cutaneous (CL) and canine (CanLei) leishmaniases are a public health concern. The risk of transmission of different Leishmania species can be studied in an area by monitoring their vectors...
February 17, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29453922/a-short-review-of-primary-aldosteronism-in-a-question-and-answer-fashion
#16
Frederick-Anthony Farrugia, Nicolaos Zavras, Georgios Martikos, Panagiotis Tzanetis, Anestis Charalampopoulos, Evangelos P Misiakos, Dimitrios Sotiropoulos, Nikolaos Koliakos
OBJECTIVES: The aim of this study was to present up to date information concerning the diagnosis and treatment of primary aldosteronism (PA). PA is the most common cause of endocrine hypertension. It has been reported up to 24% of selective referred hypertensive patients. METHODS: We did a search in Pub-Med and Google Scholar using the terms: PA, hyperaldosteronism, idiopathic adrenal hyperplasia, diagnosis of PA, mineralocorticoid receptor antagonists, adrenalectomy, and surgery...
January 1, 2018: Endocrine Regulations
https://www.readbyqxmd.com/read/29453410/molecular-characterization-of-colorectal-adenomas-with-and-without-malignancy-reveals-distinguishing-genome-transcriptome-and-methylome-alterations
#17
Brooke R Druliner, Panwen Wang, Taejeong Bae, Saurabh Baheti, Seth Slettedahl, Douglas Mahoney, Nikolaos Vasmatzis, Hang Xu, Minsoo Kim, Matthew Bockol, Daniel O'Brien, Diane Grill, Nathaniel Warner, Miguel Munoz-Gomez, Kimberlee Kossick, Ruth Johnson, Mohamad Mouchli, Donna Felmlee-Devine, Jill Washechek-Aletto, Thomas Smyrk, Ann Oberg, Junwen Wang, Nicholas Chia, Alexej Abyzov, David Ahlquist, Lisa A Boardman
The majority of colorectal cancer (CRC) arises from precursor lesions known as polyps. The molecular determinants that distinguish benign from malignant polyps remain unclear. To molecularly characterize polyps, we utilized Cancer Adjacent Polyp (CAP) and Cancer Free Polyp (CFP) patients. CAPs had tissues from the residual polyp of origin and contiguous cancer; CFPs had polyp tissues matched to CAPs based on polyp size, histology and dysplasia. To determine whether molecular features distinguish CAPs and CFPs, we conducted Whole Genome Sequencing, RNA-seq, and RRBS on over 90 tissues from 31 patients...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29452987/cell-therapy-for-peripheral-artery-disease
#18
REVIEW
Nikolaos G Frangogiannis
Patients with severe peripheral artery disease (PAD) who are not candidates for revascularization have poor prognosis. Cell therapy using peripheral blood-derived or bone marrow-derived mononuclear cells, mesenchymal stem cells, or marker-specific subsets of bone marrow cells with angiogenic properties may hold promise for no-option PAD patients. Injected cells may exert beneficial actions by enhancing local angiogenesis (either through maturation of endothelial progenitors, or through secretion of angiogenic mediators), or by transducing cytoprotective signals that preserve tissue structure...
February 13, 2018: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29452714/genetic-diversity-and-structure-of-rhizobium-leguminosarum-populations-associated-with-clover-plants-are-influenced-by-local-environmental-variables
#19
Andrei Stefan, Jannick Van Cauwenberghe, Craita M Rosu, Catalina Stedel, Nikolaos E Labrou, Emmanouil Flemetakis, Rodica C Efrose
The identification and conservation of indigenous rhizobia associated with legume plants and their application as biofertilizers is becoming an agricultural worldwide priority. However, little is known about the genetic diversity and phylogeny of rhizobia in Romania. In the present study, the genetic diversity and population composition of Rhizobium leguminosarum symbiovar trifolii isolates from 12 clover plants populations located across two regions in Romania were analyzed. Red clover isolates were phenotypically evaluated and genotyped by sequencing 16S rRNA gene, 16S-23S intergenic spacer, three chromosomal genes (atpD, glnII and recA) and two plasmid genes (nifH and nodA)...
February 3, 2018: Systematic and Applied Microbiology
https://www.readbyqxmd.com/read/29452173/energy-intake-functions-and-energy-budgets-of-ectotherms-and-endotherms-derived-from-their-ontogenetic-growth-in-body-mass-and-timing-of-sexual-maturation
#20
Jan Werner, Nikolaos Sfakianakis, Alan D Rendall, Eva Maria Griebeler
Ectothermic and endothermic vertebrates differ not only in their source of body temperature (environment vs. metabolism), but also in growth patterns, in timing of sexual maturation within life, and energy intake functions. Here, we present a mathematical model applicable to ectothermic and endothermic vertebrates. It is designed to test whether differences in the timing of sexual maturation within an animal's life (age at which sexual maturity is reached vs. longevity) together with its ontogenetic gain in body mass (growth curve) can predict the energy intake throughout the animal's life (food intake curve) and can explain differences in energy partitioning (between growth, reproduction, heat production and maintenance, with the latter subsuming any other additional task requiring energy) between ectothermic and endothermic vertebrates...
February 13, 2018: Journal of Theoretical Biology
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