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Matias Mariani, Mark William Glister Collins
PURPOSE: As developments in cancer treatment have improved outcomes, research has increasingly focused on the role of cancer-related cognitive impairment (CRCI) in quality of life for cancer survivors. Impairment profiles have been heterogeneous across studies, necessitating the study of these effects across different cohorts. The purpose of this preliminary study is to compare the memory profiles of Northeast Ontario breast and CNS cancer patients, as there is no literature which exists for profiling CRCI within this largely rural region...
May 17, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Lisa L Hyde, Allison W Boyes, Tiffany-Jane Evans, Lisa J Mackenzie, Rob Sanson-Fisher
BACKGROUND: Electronic health (eHealth) literacy is needed to effectively engage with Web-based health resources. The 8-item eHealth literacy scale (eHEALS) is a commonly used self-report measure of eHealth literacy. Accumulated evidence has suggested that the eHEALS is unidimensional. However, a recent study by Sudbury-Riley and colleagues suggested that a theoretically-informed three-factor model fit better than a one-factor model. The 3 factors identified were awareness (2 items), skills (3 items), and evaluate (3 items)...
February 19, 2018: JMIR Human Factors
Gertrud K Nürnberg, Rachele Fischer, Andrew M Paterson
Formerly acidified lakes and watersheds can become more productive when recovering from acidity, especially when exposed to anthropogenic disturbance and increased nutrient loading. Occasional toxic cyanobacterial blooms and other signs of eutrophication have been observed for a decade in lakes located in the Sudbury, Ontario, mining area that was severely affected by acid deposition before the start of smelter emission reductions in the 1970s. Oligotrophic Long Lake and its upstream lakes have been exposed to waste water input and development impacts from the City of Greater Sudbury and likely have a legacy of nutrient enrichment in their sediment...
June 1, 2018: Science of the Total Environment
Bethany R Smith, David C Aldridge, Andrew J Tanentzap
Litterfall is an important resource subsidy for lake ecosystems that primarily accumulates in littoral zones. Bivalves are abundant within littoral zones and may modify the effects of terrestrial resource subsidies through trophic interactions and engineering their surrounding habitat. Leaf inputs to lakes and freshwater mussel abundances are changing throughout the boreal ecoregion so we set out to investigate how the co-occurring benthic community might respond. We set up an in situ mesocosm experiment in Ramsey Lake, Sudbury, ON, Canada...
May 1, 2018: Science of the Total Environment
Desre M Kramer, D Linn Holness, Emily Haynes, Keith McMillan, Colin Berriault, Sheila Kalenge, Nancy Lightfoot
BACKGROUND: Miners work in highly hazardous environments, but surprisingly, there are more fatalities from occupational diseases, including cancers, than from fatalities from injuries. Over the last few decades, the mining environment has become safer with fewer injuries and less exposure to the toxins that lead to occupational disease. There have been improvements in working conditions, and a reduction in the number of workers exposed, together with an overall improvement in the health of miners...
2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
Beverley Hale, Yamini Gopalapillai, Amanda Pellegrino, Tyson Jennett, Julie Kikkert, Wilson Lau, Christian Schlekat, Mike J McLaughlin
The Existing Substances Regulation Risk Assessments by the European Union (EU RA) generated new toxicity data for soil organisms exposed to Ni added to sixteen field-collected soils with low background concentration of metals and varying physico-chemical soil characteristics. Using only effective cation exchange capacity (eCEC) as a bioavailability correction, chronic toxicity of Ni in soils with a wide range of characteristics could be predicted within a factor of two. The objective of the present study was to determine whether this was also the case for three independent data sets of Ni toxicity thresholds...
December 2017: Environmental Pollution
Brian W Kielstra, Shelley E Arnott, John M Gunn
Assessing biological recovery in damaged aquatic environments requires the consideration of multiple spatial and temporal scales. Past research has focused on assessing lake recovery from atmospheric or catchment disturbance at regional or catchment levels. Studies have also rarely considered the influences of adjacent terrestrial characteristics on within-lake habitats, such as subcatchment delta confluences. We used Hyalella azteca, a ubiquitous freshwater amphipod, as a sensitive indicator to assess the importance of local subcatchment scale factors in the context of multiscale lake recovery within the metal mining region of Sudbury, Canada following a period of major reductions in atmospheric pollution...
December 2017: Ecological Applications: a Publication of the Ecological Society of America
Christopher Thome, Sujeenthar Tharmalingam, Jake Pirkkanen, Andrew Zarnke, Taylor Laframboise, Douglas R Boreham
Considerable attention has been given to understanding the biological effects of low-dose ionizing radiation exposure at levels slightly above background. However, relatively few studies have been performed to examine the inverse, where natural background radiation is removed. The limited available data suggest that organisms exposed to sub-background radiation environments undergo reduced growth and an impaired capacity to repair genetic damage. Shielding from background radiation is inherently difficult due to high-energy cosmic radiation...
October 2017: Radiation Research
Laura Souter, Shaun A Watmough
Slag piles from mining activities are common worldwide, but in contrast to mine tailings the environmental impact of runoff from slag piles is less documented. This study was designed to assess the geochemistry and potential toxicity of water draining a large, 62.2ha slag pile in Sudbury, Ontario. The Coniston slag pile contains 12-20Mt of slag from smelting local Ni-Cu ore between 1913 and 1972. Slag leaching experiments confirmed slag is a source of sulphate (SO4 ), heavy metals (including Fe, Al, Ni, Co, Cu, Zn, Pb, Cr, Mn) and base cations (Ca, K, Mg, Na)...
December 15, 2017: Science of the Total Environment
L F White, J R Darling, D E Moser, D A Reinhard, T J Prosa, D Bullen, D Olson, D J Larson, D Lawrence, I Martin
Resolving the timing of crustal processes and meteorite impact events is central to understanding the formation, evolution and habitability of planetary bodies. However, identifying multi-stage events from complex planetary materials is highly challenging at the length scales of current isotopic techniques. Here we show that accurate U-Pb isotopic analysis of nanoscale domains of baddeleyite can be achieved by atom probe tomography. Within individual crystals of highly shocked baddeleyite from the Sudbury impact structure, three discrete nanostructural domains have been isolated yielding average (206)Pb/(238)U ages of 2,436±94 Ma (protolith crystallization) from homogenous-Fe domains, 1,852±45 Ma (impact) from clustered-Fe domains and 1,412±56 Ma (tectonic metamorphism) from planar and subgrain boundary structures...
May 26, 2017: Nature Communications
Peter Johannes Schulz, Mary Anne Fitzpatrick, Alexandra Hess, Lynn Sudbury-Riley, Uwe Hartung
BACKGROUND: Most evidence (not all) points in the direction that individuals with a higher level of health literacy will less frequently utilize the health care system than individuals with lower levels of health literacy. The underlying reasons of this effect are largely unclear, though people's ability to seek health information independently at the time of wide availability of such information on the Internet has been cited in this context. OBJECTIVE: We propose and test two potential mediators of the negative effect of eHealth literacy on health care utilization: (1) health information seeking and (2) gain in empowerment by information seeking...
May 16, 2017: Journal of Medical Internet Research
Henry Y Jiang, Erica L Kohtakangas, Kengo Asai, Jeffrey B Shum
BACKGROUND: NSQIP Risk Calculator was developed to allow surgeons to inform their patients about their individual risks for surgery. Its ability to predict complication rates and length of stay (LOS) has made it an appealing tool for both patients and surgeons. However, the NSQIP Risk Calculator has been criticized for its generality and lack of detail towards surgical subspecialties, including the hepatopancreaticobiliary (HPB) surgery. We wish to determine whether the NSQIP Risk Calculator is predictive of post-operative complications and LOS with respect to Whipple's resections for our patient population...
May 2, 2017: Journal of Gastrointestinal Cancer
Ramya Narendrula-Kotha, Kabwe K Nkongolo
Metal and sulfur dioxide (SO2) contaminations in Northern Ontario (Canada), especially in the Greater Sudbury Region (GSR) caused by mining activities have resulted in severe environmental degradations. A long term restoration program has led to significant landscape changes and healthy ecosystems. The objective of this study was to assess variation in enzymatic activities and soil respiration in metal contaminated and reclaimed ecosystems. Soil analysis revealed that respiration rates were higher in metal contaminated limed soils (65ppm) compared to adjacent unlimed areas (35ppm)...
June 2017: Ecotoxicology and Environmental Safety
Lynn Sudbury-Riley, Mary FitzPatrick, Peter J Schulz
BACKGROUND: The eHealth Literacy Scale (eHEALS) is one of only a few available measurement scales to assess eHealth literacy. Perhaps due to the relative paucity of such measures and the rising importance of eHealth literacy, the eHEALS is increasingly a choice for inclusion in a range of studies across different groups, cultures, and nations. However, despite its growing popularity, questions have been raised over its theoretical foundations, and the factorial validity and multigroup measurement properties of the scale are yet to be investigated fully...
February 27, 2017: Journal of Medical Internet Research
K N Kalubi, M Mehes-Smith, G Spiers, A Omri
Although a number of publications have provided convincing evidence that abiotic stresses such as drought and high salinity are involved in DNA methylation reports on the effects of metal contamination, pH, and cation exchange on DNA modifications are limited. The main objective of the present study is to determine the relationship between metal contamination and Cation exchange capacity (CEC) on whole DNA modifications. Metal analysis confirms that nickel and copper are the main contaminants in sampled sites within the Greater Sudbury Region (Ontario, Canada) and liming has increased soil pH significantly even after 30 years following dolomitic limestone applications...
April 2017: Ecotoxicology
Nancy E Lightfoot, Colin J Berriault, Steven K Seilkop, Bruce R Conard
Mortality and cancer incidence were examined for an updated cohort of nonsinter nickel workers in Sudbury and Port Colborne, Ontario, Canada. Abstract results are provided for those with ≥ 15 years since first exposure. For circulatory disease mortality, significant elevations were observed overall in many Sudbury work areas and in Port Colborne staff. Underground miners, with first exposure before 1960, displayed significant elevations for pneumoconiosis, as well as silicosis and anthrasilicosis, likely due to crystalline silica...
July 4, 2017: Archives of Environmental & Occupational Health
Gabriel Theriault, Kabwe Nkongolo
Nickel (Ni) and copper (Cu) are the most prevalent metals found in the soils in the Greater Sudbury Region (Canada) because of smelting emissions. The main objectives of the present study were to (1) determine the toxicity of nickel (Ni) and copper (Cu) at different doses in Betula papyrifera (white birch), (2) Characterize nickel resistance mechanism, and (3) assess segregating patterns for Ni and Cu resistance in B. papyrifera populations. This study revealed that B. papyrifera is resistant to Ni and Cu concentrations equivalent to the levels reported in metal-contaminated stands in the GSR...
August 2016: Bulletin of Environmental Contamination and Toxicology
Dominic E Ponton, Antoine Caron, Landis Hare, Peter G C Campbell
Yellow perch (Perca flavescens) collected from 11 lakes in the Canadian mining regions of Sudbury (Ontario) and Rouyn-Noranda (Quebec) display wide ranges in the concentrations of cadmium (Cd), nickel (Ni), selenium (Se), and thallium (Tl) in their livers. To determine if these trace elements, as well as copper (Cu) and zinc (Zn), are causing oxidative stress in these fish, we measured three biochemical indicators (glutathione (GSH), glutathione disulfide (GSSG) and thiobarbituric acid-reactive substances (TBARS)) in their livers...
July 2016: Environmental Pollution
Alan Lock, Graeme Spiers, Blair Hostetler, James Ray, Dirk Wallschläger
Spatial surveys of Ramsey Lake, Sudbury, Ontario water quality were conducted using an innovative underwater towed vehicle (UTV) equipped with a multi-parameter probe providing real-time water quality data. The UTV revealed underwater vent sites through high resolution monitoring of different spatial chemical characteristics using common sensors (turbidity, chloride, dissolved oxygen, and oxidation/reduction sensors) that would not be feasible with traditional water sampling methods. Multi-parameter probe vent site identification is supported by elevated alkalinity and silica concentrations at these sites...
April 15, 2016: Water Research
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