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Adomas Bunevicius, Algimantas Matukevicius, Vytenis Deltuva, Inga Gudinaviciene, Darius Pranys, Arimantas Tamasauskas
OBJECTIVE: In vitro fertilization (IVF) is increasingly used for the treatment of infertile couples worldwide. The association between IVF and cancer risk in offspring is conflicting. We present a case of atypical teratoid/rhabdoid tumor (AT/RT) in a girl conceived by IVF and present results of systematic review of literature of primary intracranial neoplasms diagnosed in children conceived by IVF. METHODS: A systematic review of literature was conducted on April 12, 2017, to identify previously published reports of intracranial brain tumors in patients conceived after IVF...
May 2018: World Neurosurgery
Sarah C Clement, Antoinette Y N Schouten-van Meeteren, Annemieke M Boot, Hedy L Claahsen-van der Grinten, Bernd Granzen, K Sen Han, Geert O Janssens, Erna M Michiels, A S Paul van Trotsenburg, W Peter Vandertop, Dannis G van Vuurden, Leontien C M Kremer, Hubert N Caron, Hanneke M van Santen
Purpose To evaluate the prevalence of, and risk factors for, early endocrine disorders in childhood brain tumor survivors (CBTS). Patients and Methods This nationwide study cohort consisted of 718 CBTS who were diagnosed between 2002 and 2012, and who survived ≥ 2 years after diagnosis. Patients with craniopharyngeoma or a pituitary gland tumor were excluded. Results of all endocrine investigations, which were performed at diagnosis and during follow-up, were collected from patient charts. Multivariable logistic regression was used to study associations between demographic and tumor- and treatment-related variables and the prevalence of early endocrine disorders...
December 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Judith Anthofer, Megan Wester, Florian Zeman, Alexander Brawanski, Karl-Michael Schebesch
OBJECTIVE: Medical complications severely impair recovery of neurosurgical patients after craniotomy. The purpose of this study was to identify patients at risk of peri- and postoperative medical complications. Therefore, we present a large population of patients with different medical complications after elective craniotomy. METHODS: We retrospectively screened all patients who had been consecutively treated at our department between June 2009 and June 2014. Patients with any postoperative thromboembolic complication or pulmonary or systemic infection were compared with a control group without any medical complication...
July 2016: World Neurosurgery
Mohammad Maarouf, Faycal El Majdoub, Manuel Fuetsch, Mauritius Hoevels, Ralph Lehrke, Frank Berthold, Jürgen Voges, Volker Sturm
PURPOSE: Although microsurgery remains the first-line treatment, gross total resection of cystic craniopharyngeomas (CP) is associated with significant morbidity and mortality and the addition of external irradiation to subtotal resection proves to achieve similar tumor control. However, concern regarding long-term morbidity associated with external irradiation in children still remains. With this retrospective analysis, the authors emphasize intracavitary brachytherapy using phosphorus-32 (P-32) as a treatment option for children with cystic CP...
March 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Trine E W Hyttel, Mette D S Wiese, Søren R Aagaard
We present a case of a young man with severe hypothermia on the basis of a large craniopharyngeoma. He had been psychologically peculiar since the age of six and had deteriorated dramatically since his late teens. Craniopharyngeomas are slowly developing benign tumours but they can cause severe damage to the neuroendocrinological systems or hypothalamus causing a wide range of symptoms including psychiatric disorders and hypothermia. Intracraniel neoplasms should be considered as a differential diagnosis in cognitive dysfunction in the young or in acute hypothermia...
March 24, 2014: Ugeskrift for Laeger
J Jesser, K Schlamp, M Bendszus
BACKGROUND AND OBJECTIVES: This article gives an overview of the most common tumors of the pituitary gland and the differential diagnostics with special emphasis on radiological diagnostic criteria. MATERIAL AND METHODS: A selective search of the literature in PubMed was carried out. RESULTS: Pituitary adenomas constitute 10-15% of all intracranial tumors and are the most common tumors of the sellar region. Tumors smaller than 1 cm in diameter are called microadenomas while those larger than 1 cm in diameter are called macroadenomas...
October 2014: Der Radiologe
A Zimmer, W Reith
The (supra) sellar and pineal regions are relatively common sites for pediatric brain tumors; however, the distinct spectrum of space-occupying lesions is in marked contrast to that of the adult population. Craniopharyngeoma represents the most common intrasellar and/or suprasellar lesion in children, whereas the pituitary adenoma typical for adults- is generally rare. The pineal region is a predilection site for germ cell tumors in pediatric patients, while in adults this cancer category is largely confined to the gonads...
August 2014: Der Radiologe
Dragana Miljic, Predrag Miljic, Mirjana Doknic, Sandra Pekic, Marko Stojanovic, Milan Petakov, Vera Popovic
Adipsic diabetes insipidus (ADI) is a rare disorder. It can occur after transcranial surgery for craniopharyngeoma, suprasellar pituitary adenoma and anterior communicating artery aneurysm but also with head injury, toluene exposure and developmental disorders. It is often associated with significant hypothalamic dysfunction and complications like obesity, sleep apnea, thermoregulatory disorders, seizures and venous thromboembolism (VTE). Morbidity and mortality data have been reported as single case reports with only one large series suggesting increased risk for VTE in patients with ADI...
July 2014: Hormones: International Journal of Endocrinology and Metabolism
D Goltz, K Schötta, H Zhou, H-P Fischer
BACKGROUND: In rare cases, hypothalamic-pituitary dysfunction can be associated with an extraordinarily active non-alcoholic steatohepatitis (NASH) and subsequent liver cirrhosis. CASE REPORT: The two young adult patients described in this report presented with NASH together with advanced liver fibrosis and cirrhosis 5 and 19 years, respectively after resection of a craniopharyngeoma. CONCLUSIONS: In young patients and children with active steatohepatitis, an association with hypothalamic-pituitary dysfunction should be excluded...
July 2013: Der Pathologe
I A Savin, A Iu Lubnin, K M Gorshkov, K A Popugaev, A S Goriachev
The paper describes a rare clinical case of severe thrombotic complications (thrombosis of the subclavian, superior vena cava and femoral veins) of the child in the postoperative period, after removal of craniopharyngeoma. The development of complications was diagnosed based on clinical symptoms and results of ultrasound. Genesis of thrombotic complications has been clarified with the help of special hemostasiological studies that confirmed the presence of acquired protein S deficiency. The matters of discussion are the problems of diagnosis and therapy of this complication...
January 2011: Anesteziologiia i Reanimatologiia
Zsuzsa Kolumbán, Katalin Bálint, Jeno Julow
OBJECTIVE: The aim of this study is to reveal the long-term effect of Yttrium-90 colloid radioisotope brachytherapy applied for the treatment of cystic craniopharyngiomas. To provide a mathematical expression that can describe the cyst reduction as a function of time in an accurate matter. METHODS: Fourteen cystic craniopharyngiomas were selected for intracavital irradiation with stereotactically implanted beta-emitting radioisotope Yttrium-90 silicate colloid. The cumulative dose aimed at the inner surface of the cyst wall was ranging between 180-300 Gy...
January 30, 2011: Ideggyógyászati Szemle
Laurentino Biccas Neto, Arthur Silva de Mesquita
Optical coherence tomography (OCT) has proved to be a very valuable tool in the assessment of patients with glaucoma. In this report, intracranial tumors were discovered in two glaucoma suspects referred for diagnostic confirmation by OCT - a clivus chordoma and a craniopharyngeoma. Optical coherence tomography findings - marked asymmetrical diffuse attenuation of the peripapillary nerve fiber layer in nasal and temporal sectors - raised concerns about lesions in chiasmatic region and permitted the timely diagnosis of these intraocular tumors...
September 2009: Arquivos Brasileiros de Oftalmologia
Susan Arndt, Thorsten Wiech, Irina Mader, Antje Aschendorff, Wolfgang Maier
Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. Nevertheless, in rare cases these entities may occur solely as extracranial lesions that may present as intranasal/sinusoidal masses, with headaches and nasal obstruction. We present three cases of common intracranial tumors, with purely extracranial extension. The three described cases demonstrate, that preoperative MRI and CT imaging is important for differential diagnosis to exclude intracranial connections of the tumors. A definitive diagnosis requires specialized immunohistochemical examinations...
2008: Diagnostic Pathology
V Hána, Z Seidl, M Vanĕcková, P Diblík, V Weiss, V Masopust, M Krsek, J Marek
Computer tomography (CT) and magnetic resonance imaging (MRI) quite often detect unexpected cases of enlargement in the hypothalamus-hypophysial region, without the above methods being indicated for clinical manifested symptomatology provoked by the tumour. This is not surprising if we consider that autopsies show the presence of hypophysial adenomas of 10-15% of population on an average. X ray, CT or MRI are indicated in the case of head traumas, lateral nasal cavity inflammations, headaches, strokes, neurological diseases and other disorders...
July 2007: Vnitr̆ní Lékar̆ství
I Grunwald, K Dillmann, C Roth, M Backens, W Reith
Magnetic resonance imaging is a routine diagnostic measure for a suspected intracerebral mass. Computed tomography is usually also indicated. Further diagnostic procedures as well as the interpretation of the findings vary depending on the tumor location. This contribution discusses the symptoms and diagnostics for supratentorial tumors separated in relation to their intra- or extracranial location. Supratentorial tumors include astrocytoma, differentiated by their circumscribed and diffuse growth, ganglioglioma, ependyoma, neurocytoma, primitive neuroectodermal tumors (PNET), oligodendroglioma, dysem-bryoplastic neuroepithelial tumors (DNET), meningoangiomatosis, pineal tumors, hamatoma, lymphoma, craniopharyngeoma and metastases...
June 2007: Der Radiologe
Bećir Heljić, Azra Bureković, Amer Iglica
INTRODUCTION: Tumors of the pituitary gland can be adenomas, and more often, cancers, representing 10-15% of intracranial neoplasm. We make a difference between them according to their size, expansion, hormone's activity and local and endocrinological manifestations. The goal of the research was to reveal the presence of tumors of the pituitary gland in the period 2000-2005 among patients hospitalized on the Intensive Care of the Endocrinology Clinic. PATIENTS AND METHODS: Data from anamnesis of all patients with verified tumor of the pituitary gland between 2000...
2006: Medicinski Arhiv
Dorota Birkholz, Maria Korpal-Szczyrska, Halina Kamińska, Ewa Bień, Katarzyna Połczyńska, Teresa Stachowicz-Stencel, Anna Szołkiewicz
INTRODUCTION: The increasing number of childhood cancer survivors has resulted in a growing interest in the late effects, which depend on type of treatment. Frequently, a brain tumour and its therapy in children are endocrinologically devastating. AIM OF STUDY: The aim of study was to compare growth and pubertal development in children after brain tumour therapy treated or not treated with recombinant growth hormone (rGH). MATERIAL AND METHODS: 18 children were included in this study...
July 2005: Medycyna Wieku Rozwojowego
M Zámecnik, P Mukensnábl, R Curík, M Michal
Two cases of adult testicular teratoma with shadow cell differentiation (SCD) similar to that seen commonly in pilomatrixoma are presented. The patients aged 21 and 27 years, and both tumors were limited to the testis. The differentiation of squamous epithelium toward shadow cells is well known in cutaneous pilomatrixoma and related lesions, some odontogenic tumors, craniopharyngeoma, and it was recently observed in several visceral carcinomas. In testicular location, SCD was so far described in benign dermoid cyst but not in teratoma, suggesting that the occurrence of shadow cells could help in differential diagnosis between these lesions...
July 2005: Ceskoslovenská Patologie
V Rohde, P Spangenberg, L Mayfrank, M Reinges, J M Gilsbach, V A Coenen
OBJECTIVE: The purpose of this study was to describe the usefulness of recent advances of neuronavigational technology in the management of skull base tumors and of vascular lesions, treated via a skull base approach. METHODS: In 16 patients (skull base meningioma n = 9, petrous apex epidermoid n = l, craniopharyngeoma n = 1, giant internal carotid artery aneurysm n = 1, basilar/vertebral artery aneurysm n = 2, brain stem cavernoma n = 2), "advanced" neuronavigation was used...
February 2005: Minimally Invasive Neurosurgery: MIN
W Müller-Forell
Intracranial pathologies involving the visual pathway are manifold. Aligning to anatomy, the most frequent and/or most important extrinsic and intrinsic intracranial lesions are presented. Clinical symptoms and imaging characteristics of lesions of the sellar region are demonstrated in different imaging modalities. The extrinsic lesions mainly consist of pituitary adenomas, meningeomas, craniopharyngeomas and chordomas. In (asymptomatic and symptomatic) aneurysms, different neurological symptoms depend on the location of aneurysms of the circle of Willis...
February 2004: European Journal of Radiology
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