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https://www.readbyqxmd.com/read/28822339/effects-of-simulated-n-deposition-on-foliar-nutrient-status-n-metabolism-and-photosynthetic-capacity-of-three-dominant-understory-plant-species-in-a-mature-tropical-forest
#1
Qinggong Mao, Xiankai Lu, Hui Mo, Per Gundersen, Jiangming Mo
Anthropogenic increase of nitrogen (N) deposition has threatened forest ecosystem health at both regional and global scales. In N-limited ecosystems, atmospheric N input is regarded as an important nutrient source for plant growth. However, it remains an open question on how elevated N deposition affects plant growth in N-rich forest ecosystems. To address this question, we used a simulated N deposition experiment in an N-rich mature tropical forest of southern China, with N addition levels as 0kgNha(-1)yr(-1) (Control), 50kgNha(-1)yr(-1) (Low-N), 100kgNha(-1)yr(-1) (Middle-N) and 150kgNha(-1)yr(-1) (High-N), respectively...
August 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822256/addressing-harmful-algal-blooms-habs-impacts-with-ferrate-vi-simultaneous-removal-of-algal-cells-and-toxins-for-drinking-water-treatment
#2
Yang Deng, Meiyin Wu, Huiqin Zhang, Lei Zheng, Yaritza Acosta, Tsung-Ta D Hsu
Although ferrate(VI) has long been recognized as a multi-purpose treatment agent, previous investigations regarding ferrate(VI) for addressing harmful algal blooms (HABs) impacts in drinking water treatment only focused on a single HAB pollutant (e.g. algal cells or algal toxins). Moreover, the performance of ferrate(VI)-driven coagulation was poorly investigated in comparison with ferrate(VI) oxidation, though it has been widely acknowledged as a major ferrate(VI) treatment mechanism. We herein reported ferrate(VI) as an emerging agent for simultaneous and effective removal of algal cells and toxins in a simulated HAB-impacted water...
August 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/28822243/chrysin-induced-sperm-parameters-and-fatty-acid-profile-changes-improve-reproductive-performance-of-roosters
#3
Ali Sami Amin Altawash, Ahmad Zare Shahneh, Hossein Moravej, Mahdi Ansari
Having antioxidant and androgenic effects, Chrysin was orally administrated to roosters and reproductive performance including sperm quality and fatty acid composition, testis index, fertility and hatchability rates as well as blood testosterone concentration were assessed. Twenty eight 40-week-old Ross 308 roosters were individually housed, equally divided into four groups and received different levels of capsulated Chrysin including 0 (Ch0), 25 (Ch25), 50 (Ch50) or 75 (Ch75) mg/bird/day for 12 consecutive weeks...
August 5, 2017: Theriogenology
https://www.readbyqxmd.com/read/28822169/-effect-factors-and-mechanisms-of-borneol-s-bidirectional-regulation-on-blood-brain-barrier-permeability
#4
Hong-Jin Wang, Jun-Jie Wu, Qiang Xue, Ji-Fen Zhang, Xiao-Yu Xu
In recent twenty years, there are a lot of studies about the effect of borneol on permeability of blood-brain barrier(BBB); however, it isDODOrt of regular conclusions of effect factors and in-depth analysis of functional mechanisms. The current researching data were collected and analyzed in this paper for illuminating the effect factors and mechanisms of borneol on permeability of BBB.The following conclusions were obtained: five factors about borneol influencing the permeability of BBB. First, opticity activity of borneol had no significant effect on action effects...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28822147/-research-on-chemotaxis-response-of-alternaria-panax-to-amino-acid-of-ginseng-root-exudates
#5
Ai-Hua Zhang, Wen-Li Ma, Feng-Jie Lei, Ning-Bo An, Xin-Xin Zhang, Zhi-Qing Liu, Lian-Xue Zhang
Plate assay and spore germination method were used to study the chemotaxis response of Alternaria panax to arginine, glutamic acid, aspartic acid and threonine. The result showed that the optimum temperature of A. panax chemotaxis response to four amino acids were all 25 ℃. And chemotaxis responses of A. panax were different under conditions of different concentration and pH value. The chemotaxin reached to the highest under the condition of 2 mg•L⁻¹ and pH value was 7 for arginine, glutamic acid and threonine while 20 mg•L⁻¹ and pH value was 6 for aspartic acid ...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28822108/semi-quantitative-metabolic-values-on-fdg-pet-ct-including-extracardiac-sites-of-disease-as-a-predictor-of-treatment-course-in-patients-with-cardiac-sarcoidosis
#6
Mitsutomi Ishiyama, Laurie A Soine, Hubert J Vesselle
BACKGROUND: Cardiac sarcoidosis is associated with major adverse cardiac events including cardiac arrest, for which anti-inflammatory treatment is indicated. Oral corticosteroid is the mainstay among treatment options; however, adverse effects are a major concern with long-term use. It would be beneficial for providers to predict treatment response and prognosis for proper management strategy of sarcoidosis, though it remains challenging. Fluorine (F)-18 fluorodeoxyglucose (FDG)-positron emission tomography(PET)/computed tomography(CT) has an advantage over anatomical imaging in providing semi-quantitative functional parameters such as standard uptake value (SUV), metabolic volume, and total lesion glycolysis (TLG), which are well-established biomarkers in oncology...
August 18, 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28822093/leonardite-derived-humic-substances-are-great-adsorbents-for-cadmium
#7
Fande Meng, Guodong Yuan, Jing Wei, Dongxue Bi, Hailong Wang
Adsorption is an important mechanism to immobilize cadmium (Cd) in soil, for which humic substances have a potential. However, commercial humic substances are either very acidic (pH = 2) or alkaline/Na(+)-enriched, making them less suitable for use in acid and saline soils. Here, we used leonardite to produce humic adsorbents HA (pH = 4.02), Ca-HA (pH = 10.9), and Ca-CPAM-HA (pH = 9.62) by using HCl, CaCl2, or CaCl2-polyacrylamide as a flocculant. Their elemental compositions, acidity, and spectroscopic properties were determined, and their Cd adsorption characteristics were assessed by batch kinetic and thermodynamic experiments at environmentally relevant concentrations...
August 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28822080/soluble-epoxide-hydrolase-inhibition-attenuates-mptp-induced-neurotoxicity-in-the-nigrostriatal-dopaminergic-system-involvement-of-%C3%AE-synuclein-aggregation-and-er-stress
#8
Hui-Ju Huang, Yi-Ting Wang, Hui-Ching Lin, Yi-Hsuan Lee, Anya Maan-Yuh Lin
Soluble epoxide hydrolase (sEH) is widely expressed in the mammalian brain and possesses dual enzymatic activities, including C-terminal epoxide hydrolase (C-EH) which degrades epoxyeicosatrienoic acid (EET), a beneficial arachidonic acid metabolite. In the present study, the neuroprotective effect of sEH inhibition on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurodegeneration of nigrostriatal dopaminergic system was investigated using genetic and pharmacological approaches. MPTP (15 mg/kg) was intraperitoneally injected in sEH knockout (KO) mice and C57BL/6J mice as wild-type (WT) mice...
August 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28822046/body-mass-index-and-clinical-response-to-intravenous-or-subcutaneous-abatacept-in-patients-with-rheumatoid-arthritis
#9
Maria-Antonietta D'Agostino, Rieke Alten, Eduardo Mysler, Manuela Le Bars, June Ye, Bindu Murthy, Julia Heitzmann, Radu Vadanici, Gianfranco Ferraccioli
This post hoc analysis of ACQUIRE (NCT00559585) explored the effect of baseline body mass index (BMI) on the pharmacokinetics of and clinical response to subcutaneous (SC) or intravenous (IV) abatacept in patients with rheumatoid arthritis (RA). ACQUIRE was a phase 3b, 6-month, double-blind, double-dummy study in which patients with RA were randomized (1:1) to SC (fixed - dose; 125 mg/week) or IV (weight-tiered; ~ 10 mg/kg/month) abatacept plus methotrexate. In this analysis, minimum abatacept plasma concentration (Cmin) was measured at 3 and 6 months, and clinical remission over 6 months was assessed by Disease Activity Score 28 (C-reactive protein; DAS28 [CRP], < 2...
August 18, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28821999/developmental-neurotoxicity-of-the-hippocampus-following-in-utero-exposure-to-methylmercury-impairment-in-cell-signaling
#10
Luana Heimfarth, Jeferson Delgado, Moara Rodrigues Mignori, Daniel Pens Gelain, José Cláudio Fonseca Moreira, Regina Pessoa-Pureur
In this study, we assessed some hippocampal signaling cascades and behavioral impairments in 30-day-old rat pups prenatally exposed to methylmercury (MeHg). Pregnant rats were exposed to 1.0 or 2.0 mg/kg MeHg by gavage in alternated days from gestational day 5 until parturition. We found increased anxiety-like and decreased exploration behavior evaluated by open field test and deficit of both short- and long-term memories by novel object recognition task, respectively, in MeHg-treated pups. Downregulated PI3K/Akt/mTOR pathway and activated/hypophosphorylated (Ser9) GSK3β in MeHg-treated pups could be upstream of hyperphosphorylated Tau (Ser396) destabilizing microtubules and contributing to neural dysfunction in the hippocampus of these rats...
August 18, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28821973/bilirubin-in-the-early-course-of-venovenous-extracorporeal-membrane-oxygenation-support-for-refractory-ards
#11
Chiara Lazzeri, Manuela Bonizzoli, Giovanni Cianchi, Stefano Batacchi, Marco Chiostri, Giorgio Enzo Fulceri, Laura Tadini Buoninsegni, Adriano Peris
Bilirubin is known as a marker of hepatic dysfunction and is incorporated in scoring algorithms to assess prognosis in critically ill patients. No data are so far available on the prognostic role of hepatic dysfunction in patients with severe ARDS on venovenous extracorporeal membrane oxygenation (VV-ECMO) support. In 112 consecutive patients with severe ARDS treated with VV-ECMO, we aimed at assessing whether increased bilirubin during the first 72 h could affect early death. Increased serum bilirubin (≥1...
August 18, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28821968/near-adult-height-in-male-kidney-transplant-recipients-started-on-growth-hormone-treatment-in-late-puberty
#12
Silvia Gil, Mariana Aziz, Marta Adragna, Marta Monteverde, Alicia Belgorosky
BACKGROUND: Growth retardation and its impact on adult height is considered to be one of the most common complications in patients with chronic kidney disease (CKD). Treatment with recombinant human growth hormone (rhGH) has been effective in improving growth in kidney transplantation (KTx) patients, but little data are available on adult height in patients who began rhGh treatment in late puberty. METHODS: Near-adult height was evaluated in 13 KTx patients treated with rhGH [growth hormone group (GHGr); dose 9...
August 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28821921/anti-nociceptive-effect-of-stigmasterol-in-mouse-models-of-acute-and-chronic-pain
#13
Cristiani Isabel Banderó Walker, Sara Marchesan Oliveira, Raquel Tonello, Mateus Fortes Rossato, Evelyne da Silva Brum, Juliano Ferreira, Gabriela Trevisan
Stigmasterol is a common sterol found in plants, but the anti-nociceptive effect of this compound and its mechanism of action are not fully explored. Thus, in the present study, the anti-nociceptive effect of stigmasterol was investigated in acute and chronic models of pain and its mechanism of action. We used adult male albino Swiss mice (25-35 g) to observe the anti-nociceptive effect of stigmasterol in acetic-acid writhing test or in complete Freund's adjuvant injection, surgical incision in hind paw, or partial sciatic nerve ligation...
August 18, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28821870/enhanced-silicon-availability-leads-to-increased-methane-production-nutrient-and-toxicant-mobility-in-peatlands
#14
Gloria-Maria Susanne Reithmaier, Klaus-Holger Knorr, Sebastian Arnhold, Britta Planer-Friedrich, Jörg Schaller
Peatlands perform important ecosystem functions, such as carbon storage and nutrient retention, which are affected, among other factors, by vegetation and peat decomposition. The availability of silicon (Si) in peatlands differs strongly, ranging from <1 to >25 mg L(-1). Since decomposition of organic material was recently shown to be accelerated by Si, the aim of this study was to examine how Si influences decomposition of carbon and nutrient and toxicant mobilization in peatlands. We selected a fen site in Northern Bavaria with naturally bioavailable Si pore water concentrations of 5 mg/L and conducted a Si addition experiment...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821869/trpm6-and-trpm7-differentially-contribute-to-the-relief-of-heteromeric-trpm6-7-channels-from-inhibition-by-cytosolic-mg-2-and-mg%C3%A2-atp
#15
Silvia Ferioli, Susanna Zierler, Joanna Zaißerer, Johann Schredelseker, Thomas Gudermann, Vladimir Chubanov
TRPM6 and its homologue TRPM7 are α-kinase-coupled divalent cation-selective channels activated upon reduction of cytosolic levels of Mg(2+) and Mg·ATP. TRPM6 is vital for organismal Mg(2+) balance. However, mechanistically the cellular role and functional nonredundancy of TRPM6 remain incompletely understood. Comparative analysis of native currents in primary cells from TRPM6- versus TRPM7-deficient mice supported the concept that native TRPM6 primarily functions as a constituent of heteromeric TRPM6/7 channels...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821801/experimental-study-of-rheological-properties-and-oil-displacement-efficiency-in-oilfields-for-a-synthetic-hydrophobically-modified-polymer
#16
Pengcheng Liu, Zhenbao Mu, Chao Wang, Yanling Wang
In a previous study, we developed a synthetic hydrophobically modified hydroxyethyl cellulose (HEC) using bromododecane (BD), which we denote as BD-HMHEC. In this work, we continually investigate the rheological properties and its oil displacement efficiency in PuTao well area in Daqing oilfields, China. Results show that BD-HMHEC solution has good viscosification, thermal-resistance, salt-tolerance, shear resistance, and acid/alkali resistance. The storage modulus (G') and the loose modulus (G") of the BD-HMHEC solutions increase significantly with increasing BD-HMHEC concentration, and the solution becomes viscoelastic at a sufficiently high BD-HMHEC concentration...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821791/determination-of-phenols-isomers-in-water-by-novel-nanosilica-polydimethylsiloxane-coated-stirring-bar-combined-with-high-performance-liquid-chromatography-fourier-transform-infrared-spectroscopy
#17
Bei Zheng, Wentao Li, Lin Liu, Xin Wang, Chen Chen, Zhiyong Yu, Hongyan Li
A novel nanosilica/polydimethylsiloxane (SiO2/PDMS) coated stirring bar was adopted in the sorption extraction (SBSE) of phenols in water, and the high performance liquid chromatography-fourier transform infrared spectroscopy (HPLC-FTIR) was subsequently used to determination of phenol concentration. The SiO2/PDMS coating was prepared by sol-gel method and characterized with respect to morphology and specific surface area. The results of field-emission scanning electron microscope (FE-SEM) and N2 adsorption-desorption as well as phenol adsorption experiments denoted that SiO2/PDMS has larger surface area and better adsorption capacity than commercial PDMS...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821706/apigenin-ameliorates-post-stroke-cognitive-deficits-in-rats-through-histone-acetylation-mediated-neurochemical-alterations
#18
Fengxia Tu, Qiongyi Pang, Tingting Huang, Yun Zhao, Meixia Liu, Xiang Chen
BACKGROUND To identify the effect of apigenin on cognitive deficits of rats after cerebral ischemia and reperfusion injury, and to investigate the potential molecular mechanisms. MATERIAL AND METHODS The rats were given sodium butyrate (NaB) or apigenin (20 or 40 mg/kg) for 28 days. Cognition was investigated by the Morris water maze (MWM) test. On day 28, the rats were euthanized and their hippocampal brain regions were used to identify biochemical and neurochemical alterations. The content of histone deacetylase (HDAC) was measured by enzyme-linked immunosorbent assay (ELISA)...
August 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28821686/effect-of-simvastatin-on-csf-alzheimer-disease-biomarkers-in-cognitively-normal-adults
#19
Ge Li, Cynthia L Mayer, Daniel Morelli, Steven P Millard, Wendy H Raskind, Eric C Petrie, Monique Cherrier, Anne M Fagan, Murray A Raskind, Elaine R Peskind
OBJECTIVE: To examine potential disease-modifying effects of statin drugs, we conducted a 12-month randomized, placebo-controlled clinical trial of simvastatin in cognitively normal adults using change in CSF Alzheimer disease biomarkers as primary outcome measure. METHODS: Participants were 45-64 years old and statin-naive with normal cognition and normal or mildly elevated cholesterol. Forty-six participants completed the 1-year study per protocol (25 in the simvastatin and 21 in the placebo group)...
August 18, 2017: Neurology
https://www.readbyqxmd.com/read/28821685/nivolumab-related-myasthenia-gravis-with-myositis-and-myocarditis-in-japan
#20
Shigeaki Suzuki, Nobuhisa Ishikawa, Fumie Konoeda, Nobuhiko Seki, Satoshi Fukushima, Kikuko Takahashi, Hisashi Uhara, Yoshikazu Hasegawa, Shinichiro Inomata, Yasushi Otani, Kenji Yokota, Takashi Hirose, Ryo Tanaka, Norihiro Suzuki, Makoto Matsui
OBJECTIVE: To report the clinical features of myasthenia gravis (MG) induced by treatment with immune checkpoint inhibitors using 2-year safety databases based on postmarketing surveys in Japan. METHODS: We studied 10,277 patients with cancer who had received monotherapy with either nivolumab or ipilimumab between September 2014 and August 2016. As the control group, 105 patients with idiopathic MG were used. RESULTS: There were 12 MG cases (0...
August 18, 2017: Neurology
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