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Hyperemesis

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https://www.readbyqxmd.com/read/28919599/clinico-biochemical-profile-of-women-with-hyperemesis-gravidarum-admitted-in-a-tertiary-hospital
#1
S Kabir, M S Basher, H Akhter, T Latif, S N Akhter, R K Karmoker, S A Shaon, K Ahmed
Hyperemesis gravidarum is the most severe form of nausea and vomiting in pregnancy with poor pregnancy outcome. Hormonal changes, psychological and immunological factors are attributed to the condition. Recently, prevalence of Helicobacter pylori among women with Hyperemesis gravidarum has been revealed. A descriptive, cross-sectional study was carried out at antenatal ward, Department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital, Mymensingh among thirty-six purposively selected patients with Hyperemesis gravidarum to assess the clinic-biochemical profile...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28868172/unique-liver-disease-of-pregnancy-requiring-anaesthesia-support-a-case-with-severe-hyperemesis-gravidarum
#2
Berrin Günaydın, Aykut Özek, Naciye Türk Özterlemez, Ayca Taş Tuna
Hyperemesis gravidarum (HG) is one of the common unique liver diseases that occurs during pregnancy. Mild cases can be spontaneously resolved in time but severe cases usually require supportive medical treatment to relieve symptoms. Moreover, differential diagnosis may be required in severe cases that manifest with persistent nausea-vomiting, dehydration and weight loss refractory to treatment. Thus, to rule out any gastrointestinal pathology, this case was referred to the outpatient anaesthesia clinic after the first unsuccessful awake endoscopy attempt without sedation...
August 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28864557/over-the-scope-clip-system-secured-nasojejunal-tube-feeding-in-refractory-hyperemesis-gravidarum
#3
Jan Kubovy, Agnieszka Them, Rees Cameron, Fali Langdana
Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy. It complicates up to 2% of all pregnancies and can be associated with adverse outcomes. Its management commonly involves a combination pharmacotherapy, however, the efficacy of such treatment is limited. Supplemental nutrition is often required in refractory cases. Enteral route is preferred over parenteral, given the high rate of intravenous catheter-related complications. Enteral feeding tube placement can be challenging and is commonly thwarted by dislodgement...
September 1, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28857251/hospital-admission-for-hyperemesis-gravidarum-in-women-at-increased-risk-of-spontaneous-preterm-birth
#4
Ira Kleine, Ana Da Silva, Wafaa Ahmed, Frida Forya, Sara M Whitten, Anna L David, Catherine P James
BACKGROUND: Progesterone administration prevents spontaneous preterm birth (sPTB) in women at increased risk. Progesterone concentration is lower in women with subsequent sPTB. Conversely, high concentrations of progesterone are implicated in the pathogenesis of hyperemesis gravidarum (HG). We hypothesized that women at increased risk of sPTB or spontaneous late miscarriage would be less likely to have a diagnosis of HG. To explore this hypothesis, we compared the incidence of HG in women at increased risk of sPTB and women with no identifiable risk factors...
August 30, 2017: Birth
https://www.readbyqxmd.com/read/28842762/hyperemesis-gravidarum-and-the-risk-of-emotional-distress-during-and-after-pregnancy
#5
Helena Kames Kjeldgaard, Malin Eberhard-Gran, Jūratė Šaltytė Benth, Åse Vigdis Vikanes
Hyperemesis gravidarum (HG) is a pregnancy condition characterised by severe nausea and vomiting. Previous studies have shown an association between HG and depressive symptoms during pregnancy, but little is known about the risk of maternal psychological distress following an HG pregnancy. The objective of the current study was therefore to assess the association between HG and emotional distress during and after pregnancy. This was a population-based pregnancy cohort study using data from the Norwegian Mother and Child Cohort Study...
August 25, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28835305/cannabinoid-hyperemesis-syndrome-presentation-to-the-emergency-department-a-two-year-multicentre-retrospective-chart-review-in-a-major-urban-area
#6
Jeremy M Hernandez, Jared Paty, Ira M Price
OBJECTIVE: Cannabinoid hyperemesis syndrome (CHS) is a paradoxical side effect of cannabis use. Patients with CHS often present multiple times to the emergency department (ED) with cyclical nausea, vomiting, and abdominal pain, and are discharged with various misdiagnoses. CHS studies to date are limited to case series. The objective was to examine the epidemiology of CHS cases presenting to two major urban tertiary care centre EDs and one urgent care centre over a 2-year period. METHODS: Using explicit variables, trained abstractors, and standardized abstraction forms, we abstracted data for all adults (ages 18 to 55 years) with a presenting complaint of vomiting and/or a discharge diagnosis of vomiting and/or cyclical vomiting, during a 2-year period...
August 24, 2017: CJEM
https://www.readbyqxmd.com/read/28800668/-epidemiology-risk-factors-and-risk-stratification-of-venous-thromboembolism-in-pregnancy-and-the-puerperium
#7
Panagiotis Tsikouras, Georg-Friedrich von Tempelhoff, Werner Rath
Venous thromboembolism (VTE) remains a leading cause of direct maternal deaths in the developed countries. The incidence of VTE has increased significantly during the past two decades. The absolute risk of VTE is estimated 0.6-2.2 per 1000 deliveries. Compared with age-matched non-pregnant women, the daily risk of VTE is increased 7- to 10-fold for antepartum VTE, but it is 15- to 35-fold for postpartum VTE. The incidence of pulmonary embolism (PE) during the first 6 weeks postpartum is nearly 15-fold higher compared to the incidence in pregnancy, and remains significantly increased up to 12 weeks postpartum...
August 2017: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/28797671/pregnancy-after-bariatric-surgery-the-effect-of-time-to-conception-on-pregnancy-outcomes
#8
Patricia O Yau, Manish Parikh, John K Saunders, Patricia Chui, Tara Zablocki, Akuezunkpa Ude Welcome
BACKGROUND: At our medical center, female patients who have undergone bariatric surgery are advised to defer pregnancy for 2 years after surgery to avoid the following complications and their potential consequences for the fetus: inadequate gestational weight gain, inadequate postsurgical weight loss, hyperemesis gravidarum, nutritional deficiencies, gestational diabetes, and gestational hypertension. OBJECTIVES: To examine the effect of time from surgery to conception on pregnancy course and outcomes in bariatric patients...
July 17, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28793989/early-enteral-tube-feeding-in-optimizing-treatment-of-hyperemesis-gravidarum-the-maternal-and-offspring-outcomes-after-treatment-of-hyperemesis-by-refeeding-mother-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Iris J Grooten, Marjette H Koot, Joris Am van der Post, Joke Mj Bais, Carrie Ris-Stalpers, Christiana Naaktgeboren, Henk A Bremer, David P van der Ham, Wieteke M Heidema, Anjoke Huisjes, Gunilla Kleiverda, Simone Kuppens, Judith Oeh van Laar, Josje Langenveld, Flip van der Made, Mariëlle G van Pampus, Dimitri Papatsonis, Marie-José Pelinck, Paula J Pernet, Leonie van Rheenen, Robbert J Rijnders, Hubertina Cj Scheepers, Tatjana E Vogelvang, Ben W Mol, Tessa J Roseboom, Rebecca C Painter
Background: Hyperemesis gravidarum (HG) leads to dehydration, poor nutritional intake, and weight loss. HG has been associated with adverse pregnancy outcomes such as low birth weight. Information about the potential effectiveness of treatments for HG is limited.Objective: We hypothesized that in women with HG, early enteral tube feeding in addition to standard care improves birth weight.Design: We performed a multicenter, open-label randomized controlled trial [Maternal and Offspring outcomes after Treatment of HyperEmesis by Refeeding (MOTHER)] in 19 hospitals in the Netherlands...
September 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28768653/the-dilemma-of-hyperemesis-gravidarum-more-answers-and-more-questions
#10
Rupsa C Boelig
No abstract text is available yet for this article.
September 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28766490/validated-analytical-methods-for-the-determination-of-drugs-used-in-the-treatment-of-hyperemesis-gravidarum-in-multiple-formulations
#11
Ahmed S Saad, Ibrahim A Naguib, Mohammed E Draz, Hala E Zaazaa, Adel S Lashien
Quantitative multicomponent analysis is considered an analytical goal to save time and cost in analysis. Hence, this work aimed to provide sensitive and selective UV-spectrophotometric, chemometric manipulation, and ultra-performance LC (UPLC) methods for the determination of well-known coformulated antiemetics used in pregnancy, namely pyridoxine HCl (PYR), meclozine HCl, and cyclizine. The developed UV-spectrophotometric methods are dual wavelength in ratio spectra and first derivative of the ratio spectra with which PYR was determined selectively at 290...
August 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28765488/wernicke%C3%A3-%C3%A2-%C3%A2-s-encephalopathy-associated-with-liver-abscess
#12
Rajesh Verma, Vipul Garg
Wernicke's encephalopathy is a rare neurological disorder caused by thiamine deficiency, characterised by ocular motor dysfunction, ataxia and impairment in consciousness. It predominantly affects brain regions with a high metabolic rate such as mammillary bodies, medial thalamic nuclei, the tectal region and the cerebellum. Although chronic alcoholism is the most common cause of Wernicke's encephalopathy, various other conditions not related to alcohol consumption such as bariatric surgery, acute pancreatitis, hyperemesis gravidarum, prolonged fasting and gastrointestinal surgery have been implicated in its aetiology...
July 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28761227/acute-kidney-injury-in-pregnancy-specific-disorders
#13
REVIEW
J Prakash, V C Ganiger
The incidence of acute kidney injury in pregnancy (P-AKI) has declined significantly over the last three decades in developing countries. However, it is still associated with significant fetomaternal mortality and morbidity. The diagnosis of P-AKI is based on the serum creatinine increase. The usual formulas for estimating glomerular filtration rate (GFR) are not validated in this population. The incidence of P-AKI with respect to total AKI cases has decreased in the last three decades from 25% in 1980s to 9% in 2000s at our centre...
July 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/28752511/wernicke-s-encephalopathy-after-bariatric-surgery-with-atypical-magnetic-resonance-imaging-a-case-report
#14
Bo-An Chen, Lu-An Chen Chen
Wernicke's encephalopathy (WE) is a disease caused by thiamine deficiency related to alcoholism, hyperemesis, or thiamine malabsorption. The clinical manifestations of WE are mental change, ataxia, and ophthalmoplegia. The typical magnetic resonance imaging (MRI) findings of WE are symmetrical involvement of medial thalamus, periventricular region of the third ventricle, periaqueductal area, and mammillary body. The atypical MRI findings are more common in nonalcoholic WE. Since the increasing population of obesity and the preference of weight loss surgery, the risk of developing thiamine deficiencies associated with weight loss surgery has become a considerable etiology of WE...
March 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/28749713/safety-considerations-surrounding-use-of-treatment-options-for-nausea-and-vomiting-in-pregnancy
#15
Gideon Koren
Nausea and vomiting of pregnancy (NVP) is the most prevalent medical condition during gestation, affecting up to 85% of pregnant women. Many of them hesitate to use medications due to perceived fetal risks. Areas covered: There are two main aspects to medication safety in NVP: The fetal safety of drugs used to treat NVP symptoms, and the risks of untreated NVP. While mild and moderate NVP are not associated with major increase in fetal or maternal risks, and may render protective fetal effects, they have major impact on the quality of life of the mother...
August 9, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28730896/cannabinoid-hyperemesis-syndrome-potential-mechanisms-for-the-benefit-of-capsaicin-and-hot-water-hydrotherapy-in-treatment
#16
John R Richards, Jeff M Lapoint, Guillermo Burillo-Putze
INTRODUCTION: Cannabinoid hyperemesis syndrome is a clinical disorder that has become more prevalent with increasing use of cannabis and synthetic cannabinoids, and which is difficult to treat. Standard antiemetics commonly fail to alleviate the severe nausea and vomiting characteristic of the syndrome. Curiously, cannabinoid hyperemesis syndrome patients often report dramatic relief of symptoms with hot showers and baths, and topical capsaicin. OBJECTIVES: In this review, we detail the pharmacokinetics and pharmacodynamics of capsaicin and explore possible mechanisms for its beneficial effect, including activation of transient receptor potential vanilloid 1 and neurohumoral regulation...
July 21, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28730852/cannabinoid-hyperemesis-syndrome-and-topical-capsaicin-treating-smoke-with-fire-the-authors-reply
#17
Zachary Hafez, Michael E Mullins, Eike Blohm, Mark J O'Connor, Laurel Dezieck, Evan S Schwarz, Albert Conicella
No abstract text is available yet for this article.
July 21, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28730165/plasma-free-fatty-acids-in-hyperemesis-gravidarum-pregnancy
#18
Mustafa Ulubay, Mustafa Ozturk, Ozlem Ozturk, Ugur Keskin, Ulas Fidan, Erdim Sertoglu, Hakan Aydin, Ali Yilmaz, Mufit Cemal Yenen
We evaluated the free fatty acids differences in plasma between hyperemesis gravidarum(HG) and healthy pregnant in first trimester pregnancy. OBJECTIVE: We aimed to compare the plasma levels of DHA, AA and EPA, between HG patients and healthy pregnant women. DESIGN: Fifty-two pregnants were involved in the study. Twenty-six pregnants of them were HG as study group, and twenty-six pregnants were enrolled as healthy pregnant women at the similar gestational age. The saturated fatty acids C14, C15, C16, C18, C20, C22, and C24; the omega-3 fatty acids eicosapentaenoic acid, (EPA) and docosahexaenoic acid, (DHA); the omega-6 fatty acids linoleic acid, arachidonic acid (AA), and homo-gamma-linolenic acid; and the omega-9 fatty acids oleic acid, erucic acid, and nervonic acid were analysed by gas chromatography...
2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28727131/evaluation-of-the-hematologic-system-as-a-marker-of-subclinical-inflammation-in-hyperemesis-gravidarum-a-case-control-study
#19
Fatma Beyazit, Filiz Halici Öztürk, Eren Pek, Mesut Abdülkerim Ünsal
OBJECTIVES: Current evidence suggests that subclinical inflammation plays a significant role in the development of hyperemesis gravidarum (HEG). Simple hematological markers, such as mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), have been shown to reflect inflammatory burden and disease activity in several disorders. This study aimed to determine the diagnostic value of these hematological parameters for HEG. MATERIAL AND METHODS: A total of 54 HEG patients and 58 age- and gestational-age-matched control subjects were studied...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28723278/a-case-of-cannabinoid-hyperemesis-syndrome-with-heliobacter-pylori-and-preeclampsia-during-pregnancy
#20
Madeline Manning Meurer, Kalyan Chakrala, Dinesh Gowda, Charles Burns, Randall Kelly, Natalia Schlabritz-Loutsevitch
BACKGROUND: The condition termed cannabinoid hyperemesis syndrome (CHS) was characterized a decade ago by Allen et al. and includes cyclic episodes of nausea and vomiting and the learned behavior of hot bathing in individuals with chronic cannabis abuse. During pregnancy, the differential diagnosis of this syndrome is challenging, since it can be masked by typical symptoms of early pregnancy or by hyperemesis gravidarum, a complication of early pregnancy associated with excessive nausea and vomiting...
July 19, 2017: Substance Abuse
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