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Nutrigenetic counseling

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https://www.readbyqxmd.com/read/28835639/dietary-fat-intake-modulates-effects-of-a-frequent-ace-gene-variant-on-glucose-tolerance-with-association-to-type-2-diabetes
#1
Rita Schüler, Martin A Osterhoff, Turid Frahnow, Matthias Möhlig, Joachim Spranger, Darko Stefanovski, Richard N Bergman, Li Xu, Anne-Cathrin Seltmann, Stefan Kabisch, Silke Hornemann, Michael Kruse, Andreas F H Pfeiffer
The frequent ACE insertion/deletion polymorphism (I/D) is, albeit inconsistently, associated with impaired glucose tolerance and insulin resistance. We recently observed an enhanced upregulation of ACE by elevated fat intake in GG-carriers of the I/D-surrogate rs4343 variant and therefore investigated its potential nutrigenetic role in glucose metabolism. In this nutritional intervention study 46 healthy and non-obese twin pairs consumed recommended low fat diets for 6 weeks before they received a 6-week high fat (HF) diet under isocaloric conditions...
August 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28695325/a-modified-response-of-nafld-patients-with-non-significant-fibrosis-in-nutritional-counseling-according-to-gckr-rs1260326
#2
Andriana C Kaliora, Ioanna Panagiota Kalafati, Aristea Gioxari, Anastasia Diolintzi, Alexandros Kokkinos, George V Dedoussis
AIM: To investigate the association between GCKR gene and nutritional treatment in NAFLD-related biomarkers. METHODS: This was an open-label and single-arm clinical trial in 44 overweight or obese adults with NAFLD receiving nutritional counseling for 6 months. Nutritional data, MedDietScore, clinical, biochemical, inflammatory and oxidative stress biomarkers were evaluated before and after intervention. Further, we genotyped GCKR rs1260326 and in T-allele carriers and non-Τ-carriers we assessed associations between the GCKR variant and nutritional counseling related to change in all biomarkers evaluated...
July 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/25672471/direct-to-consumer-genetic-testing-in-slovenia-availability-ethical-dilemmas-and-legislation
#3
Irena Vrecar, Borut Peterlin, Natasa Teran, Luca Lovrecic
INTRODUCTION: Over the last few years, many private companies are advertising direct-to-consumer genetic testing (DTC GT), mostly with no or only minor clinical utility and validity of tests and without genetic counselling. International professional community does not approve provision of DTC GT and situation in some EU countries has been analysed already. The aim of our study was to analyse current situation in the field of DTC GT in Slovenia and related legal and ethical issues. MATERIALS AND METHODS: Information was retrieved through internet search, performed independently by two authors, structured according to individual private company and the types of offered genetic testing...
2015: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/20718507/proteomics-in-nutrition-status-quo-and-outlook-for-biomarkers-and-bioactives
#4
REVIEW
Martin Kussmann, Alexandre Panchaud, Michael Affolter
Food and beverages are the only physical matter we take into our body, if we disregard the air we inhale and the drugs we may have to apply. While traditional nutrition research has aimed at providing nutrients to nourish populations and preventing specific nutrient deficiencies, it more recently explores health-related aspects of individual bioactive components as well as entire diets and this at group rather than population level. The new era of nutrition research translates empirical knowledge to evidence-based molecular science...
October 1, 2010: Journal of Proteome Research
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