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https://www.readbyqxmd.com/read/27912995/rehabilitation-strategies-and-outcomes-of-the-sarcoma-patient
#1
REVIEW
Sean Robinson Smith
Sarcomas are a relatively rare cancer that, depending on the location, can cause significant neuromusculoskeletal dysfunction and require rehabilitation interventions to reduce pain, restore function, and improve quality of life. This review focuses on sarcoma subtypes that frequently cause these complications: bony and soft tissue sarcomas leading to limb salvage or amputation, desmoid tumors, and malignant peripheral nerve sheath tumors. Rehabilitation approaches and outcomes are discussed, as well as considerations for childhood sarcoma survivors transitioning to adulthood...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27905981/correlates-of-meal-skipping-in-young-adults-a-systematic-review
#2
REVIEW
Felicity J Pendergast, Katherine M Livingstone, Anthony Worsley, Sarah A McNaughton
BACKGROUND: Meal skipping rates may be highest during young adulthood, a period of transition and development. Although these dietary behaviours may increase future risk of chronic disease, limited research has investigated correlates of meal skipping in young adults. METHODS: A systematic literature search was conducted to identify studies that investigated correlates of meal skipping behaviours in young adults (aged 18-30 years). EBSCO host, MEDLINE Complete, Global Health, Scopus, EMBASE, Web of Science and Informit platforms were searched for eligible articles...
December 1, 2016: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/27899163/human-fetal-and-adult-epicardial-derived-cells-a-novel-model-to-study-their-activation
#3
Asja T Moerkamp, Kirsten Lodder, Tessa van Herwaarden, Esther Dronkers, Calinda K E Dingenouts, Fredrik C Tengström, Thomas J van Brakel, Marie-José Goumans, Anke M Smits
BACKGROUND: The epicardium, a cell layer covering the heart, plays an important role during cardiogenesis providing cardiovascular cell types and instructive signals, but becomes quiescent during adulthood. Upon cardiac injury the epicardium is activated, which includes induction of a developmental gene program, epithelial-to-mesenchymal transition (EMT) and migration. However, the response of the adult epicardium is suboptimal compared to the active contribution of the fetal epicardium to heart development...
November 29, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27892809/civil-capacity-in-transition-age-youth-with-history-of-central-nervous-system-compromise-a-review
#4
Jacobus Donders
OBJECTIVE: The purpose of this paper is to review various aspects of decision-making capacities in children and adolescents with a history of central nervous system compromise over the course of development and into transition to adulthood. METHOD: The literature on consent capacity in various domains is reviewed, with reference to state-specific legal definitions and requirements, and illustrated with a case example. CONCLUSIONS: Neuropsychologists who use an evidence-based assessment approach, and who can clearly communicate their findings in reference to specific probate court standards, can make a unique contribution to the legal system while serving their clients who are transitioning from adolescence into adulthood...
November 28, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27882406/bowel-perforation-after-liver-transplantation-for-biliary-atresia-a-retrospective-study-of-care-in-the-transition-from-children-to-adulthood
#5
Yusuke Yanagi, Toshiharu Matsuura, Makoto Hayashida, Yoshiaki Takahashi, Koichiro Yoshimaru, Genshirou Esumi, Tomoaki Taguchi
PURPOSE: We evaluated the outcomes of liver transplantation (LT) in pediatric and adult patients with biliary atresia (BA). We focused on bowel perforation after LT (BPLT) as the most common surgical complication and analyzed its risk factors. METHODS: This was a retrospective analysis of 70 BA patients who underwent LT. The patients were divided into three groups according to the timing of LT: within the first year of age (Group A), between 1 and 12 years of age (Group B), and after 12 years of age (Group C)...
November 23, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27881047/cambodian-boys-transitions-into-young-adulthood-exploring-the-influence-of-societal-and-masculinity-norms-on-young-men-s-health
#6
Leah Scandurra, Daro Khorn, Thana-Ashley Charles, Marni Sommer
A growing body of evidence focuses on the experiences of young men in low-income countries, including their health vulnerabilities. Much of this research has been conducted in sub-Saharan Africa, Asia and Latin America. Limited evidence exists on the norms influencing boys' transitions into young adulthood in Southeast Asia, and in Cambodia in particular. To help fill this gap, we conducted a comparative case study using participatory methods with 16-19-year-old young men in rural and urban Cambodia, and with the adults who intersect in their lives...
November 24, 2016: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/27880789/targeting-ruminative-thinking-in-adolescents-at-risk-for-depressive-relapse-rumination-focused-cognitive-behavior-therapy-in-a-pilot-randomized-controlled-trial-with-resting-state-fmri
#7
Rachel H Jacobs, Edward R Watkins, Amy T Peters, Claudia G Feldhaus, Alyssa Barba, Julie Carbray, Scott A Langenecker
: This pilot randomized control trial was designed to examine whether Rumination-Focused Cognitive Behavior Therapy (RFCBT) reduces rumination and residual depressive symptoms among adolescents with a history of Major Depressive Disorder (MDD) who are at risk for relapse. We also examined whether these changes in symptoms were associated with changes in functional connectivity of the posterior cingulate cortex (PCC), a key node in the default mode network (DMN). Thirty-three adolescents (ages 12-18) were randomized to eight weeks of RFCBT or an assessment only (AO) control...
2016: PloS One
https://www.readbyqxmd.com/read/27879003/risk-and-protective-processes-predicting-rural-african-american-young-men-s-substance-abuse
#8
Junhan Cho, Steven M Kogan
Informed by a life course perspective, this study tested a cascade model linking harsh, unresponsive parenting during childhood to young African American men's substance abuse via precocious transitions, economic instability, and future orientation. The moderating influence of community disadvantage and romantic partner support on the hypothesized pathways was also examined. At the baseline, the sample included 505 African American men between ages 19 and 22 years from high-poverty rural communities. Follow-up data were collected 18 months after baseline...
November 23, 2016: American Journal of Community Psychology
https://www.readbyqxmd.com/read/27876268/vocal-changes-accompanying-the-descent-of-the-larynx-during-ontogeny-from-neonates-to-adults-in-male-and-female-goitred-gazelles-gazella-subgutturosa
#9
Ilya A Volodin, Kseniya O Efremova, Roland Frey, Natalia V Soldatova, Elena V Volodina
The pronouncedly enlarged and descended larynx in male goitred gazelles (Gazella subgutturosa), Mongolian gazelles (Procapra gutturosa) and fallow deer (Dama dama) represents an interesting parallel to the 'Adam's apple' of human males. Goitred gazelles, as humans, are not born with a descended larynx. Therefore the sexual dimorphism of larynx size and position develops during ontogeny. In this study, the vocal ontogeny of male and female goitred gazelles was investigated across five age classes from neonates to adults...
September 12, 2016: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/27871267/sedentary-lifestyle-and-its-associated-factors-among-adolescents-from-public-and-private-schools-of-a-brazilian-state-capital
#10
Flávia Miquetichuc Nogueira Nascente, Thiago Veiga Jardim, Maria do Rosário Gondim Peixoto, Carolina de Souza Carneiro, Karla Lorena Mendonça, Thaís Inácio Rolim Póvoa, Ana Luiza Lima Sousa, Weimar Kunz Sebba Barroso, Paulo César Brandão Veiga Jardim
BACKGROUND: Adolescence is a transition stage between childhood and adulthood and is an important phase for the acquisition of future lifestyles, including the practice of physical activity (PA). The prevalence of sedentary lifestyle in adolescents is often high, creating the need for studies addressing the practice of PA and its associated factors for a better understanding of the phenomenon and possible interventions that would encourage positive changes. METHODS: Cross-sectional study of a representative sample of students aged 14-18 years enrolled in both public and private schools of a large Brazilian city to determine the level of physical activity (PA) and its associated factors...
November 21, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27870212/ancestral-androgenic-differentiation-pathways-are-repurposed-during-the-evolution-of-adult-sexual-plasticity
#11
Eric R Schuppe, Tessa K Solomon-Lane, Devaleena S Pradhan, Kevin Thonkulpitak, Matthew S Grober
Although early exposure to androgens is necessary to permanently organize male phenotype in many vertebrates, animals that exhibit adult sexual plasticity require mechanisms that prevent early fixation of genital morphology and allow for genital morphogenesis during adult transformation. In Lythrypnus dalli, a teleost fish that exhibits bi-directional sex change, adults display dimorphic genitalia morphology despite the absence of sex differences in the potent fish androgen 11-ketotestosterone. Based on conserved patterns of vertebrate development, two steroid-based mechanisms may regulate the early development and adult maintenance of dimorphic genitalia; local androgen receptor (AR) and steroidogenic enzyme expression...
December 2016: Evolution & Development
https://www.readbyqxmd.com/read/27865017/isolated-thoughts-and-feelings-and-unsolved-concerns-adolescents-and-parents-perspectives-on-living-with-type-1-diabetes-a-qualitative-study-using-visual-storytelling
#12
Pernille Castensøe-Seidenfaden, Grete Teilmann, Finn Kensing, Eva Hommel, Birthe Susanne Olsen, Gitte Reventlov Husted
AIMS AND OBJECTIVES: To explore and describe the experiences of adolescents and their parents living with type 1 diabetes (T1DM), to identify their needs for support to improve adolescents' self-management skills in the transition from child- to adulthood. BACKGROUND: Adolescents with T1DM often experience deteriorating glycemic control and distress. Parents are important in adolescents' ability to self-manage T1DM, but they report anxiety and frustrations. A better understanding of the challenges adolescents and parents face, in relation to the daily self-management of T1DM, is important to improve clinical practice...
November 16, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27863320/the-effect-of-childhood-adversity-on-4-year-outcome-in-individuals-at-ultra-high-risk-for-psychosis-in-the-dutch-early-detection-intervention-evaluation-edie-nl-trial
#13
Tamar C Kraan, Helga K Ising, Marjolein Fokkema, Eva Velthorst, David P G van den Berg, Margot Kerkhoven, Wim Veling, Filip Smit, Don H Linszen, Dorien H Nieman, Lex Wunderink, Nynke Boonstra, Rianne M C Klaassen, Sara Dragt, Judith Rietdijk, Lieuwe de Haan, Mark van der Gaag
Childhood adversity is associated with a range of mental disorders, functional impairment and higher health care costs in adulthood. In this study we evaluated if childhood adversity was predictive of adverse clinical and functional outcomes and health care costs in a sample of patients at ultra-high risk (UHR) for developing a psychosis. Structural Equation Modeling was used to examine the effect of childhood adversity on depression, anxiety, transition to psychosis and overall functioning at 4-year follow-up...
November 11, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27852581/management-of-children-and-young-people-with-vision-impairment-diagnosis-developmental-challenges-and-outcomes
#14
REVIEW
Sue Keil, Alistair Fielder, Jenefer Sargent
Vision impairment (VI) has a significant impact on an individual's ability to engage with everyday tasks. Severe early-onset VI presents different challenges to adult onset visual loss since reduced visual input presents a major obstacle to the acquisition and development of fundamental developmental skills in early and later childhood. Early referral of the child with reduced vision is vital to ensure accurate diagnosis and prompt treatment of any modifiable aspects of the condition. Guidance to ensure optimisation of developmental opportunity through adaptation of play and care is vital from the earliest stages...
November 16, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27852280/treatment-management-during-the-adolescent-transition-period-of-girls-and-young-women-with-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome-mrkhs-a-systematic-literature-review
#15
REVIEW
Anke Wagner, Sara Yvonne Brucker, Esther Ueding, Dagmar Gröber-Grätz, Elisabeth Simoes, Katharina Rall, Andrea Kronenthaler, Norbert Schäffeler, Monika A Rieger
INTRODUCTION: In health services research, there is a special emphasis on the transition from adolescence into adulthood. During this transition period, adolescents change from pediatric to adult medical care. This process must be carefully structured, particularly when special medical care is required. Challenges and difficulties become apparent particularly in the case of rare diseases. This is increasingly so when the rare disease affects the adolescence-specific development of patients, such as Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS), also known as Müllerian agenesis...
November 16, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27833209/influence-of-sex-steroid-hormones-on-the-adolescent-brain-and-behavior-an-update
#16
Pilar Vigil, Juan Pablo Del Río, BÁrbara Carrera, Florencia C ArÁnguiz, Hernán Rioseco, Manuel E Cortés
This review explains the main effects exerted by sex steroids and other hormones on the adolescent brain. During the transition from puberty to adolescence, these hormones participate in the organizational phenomena that structurally shape some brain circuits. In adulthood, this will propitiate some specific behavior as responses to the hormones now activating those neural circuits. Adolescence is, then, a critical "organizational window" for the brain to develop adequately, since steroid hormones perform important functions at this stage...
August 2016: Linacre Quarterly
https://www.readbyqxmd.com/read/27830350/longitudinal-changes-in-audiometric-phenotypes-of-age-related-hearing-loss
#17
Kenneth I Vaden, Lois J Matthews, Mark A Eckert, Judy R Dubno
Presbyacusis, or age-related hearing loss, can be characterized in humans as metabolic and sensory phenotypes, based on patterns of audiometric thresholds that were established in animal models. The metabolic phenotype is thought to result from deterioration of the cochlear lateral wall and reduced endocochlear potential that decreases cochlear amplification and produces a mild, flat hearing loss at lower frequencies coupled with a gradually sloping hearing loss at higher frequencies. The sensory phenotype, resulting from environmental exposures such as excessive noise or ototoxic drugs, involves damage to sensory and non-sensory cells and loss of the cochlear amplifier, which produces a 50-70 dB threshold shift at higher frequencies...
November 9, 2016: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27829442/emerging-adults-in-substance-misuse-intervention-preintervention-characteristics-and-responses-to-a-motivation-enhancing-program
#18
Blair Beadnell, Michele A Crisafulli, Pamela A Stafford, Erin A Casey
BACKGROUND: Emerging adulthood is an age of particularly risky behavior. Substance misuse during this phase of life can be the beginning of longer-term problems, making intervention programs particularly important. This study's purposes were to identify alcohol use profile subgroups, describe the preintervention characteristics of each, and assess how many participants transitioned to lower-risk profiles during the course of the intervention. METHODS: We used latent transition analyses to categorize 1183 people court ordered to attend Prime For Life(®) (PFL), a motivation-enhancing program, into preintervention and postintervention profiles...
November 9, 2016: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/27827365/neural-correlates-of-working-memory-development-in-adolescent-primates
#19
Xin Zhou, Dantong Zhu, Xue-Lian Qi, Sihai Li, Samson G King, Emilio Salinas, Terrence R Stanford, Christos Constantinidis
Working memory ability matures after puberty, in parallel with structural changes in the prefrontal cortex, but little is known about how changes in prefrontal neuronal activity mediate this cognitive improvement in primates. To address this issue, we compare behavioural performance and neurophysiological activity in monkeys as they transitioned from puberty into adulthood. Here we report that monkeys perform working memory tasks reliably during puberty and show modest improvement in adulthood. The adult prefrontal cortex is characterized by increased activity during the delay period of the task but no change in the representation of stimuli...
November 9, 2016: Nature Communications
https://www.readbyqxmd.com/read/27826745/a-person-centered-analysis-of-risk-factors-that-compromise-wellbeing-in-emerging-adulthood
#20
Sarah E Newcomb-Anjo, Erin T Barker, Andrea L Howard
The transition to adulthood is a major life course transition that can pose risk to wellbeing. Research is needed to identify patterns of risk for compromised wellbeing, in order to best identify supports for individuals during this potentially vulnerable transition. The purpose of this study was to identify profiles of risk in an emerging adulthood sample, and to relate these profiles to mental health and subjective and academic wellbeing. Undergraduate emerging adults (N = 903, 82 % female), aged 18-25 years (M = 21...
November 8, 2016: Journal of Youth and Adolescence
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