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Natane Barbosa Barcelos, Lorena de Freitas E Silva, Regyane Ferreira Guimarães Dias, Hélio Ranes de Menezes Filho, Rosângela Maria Rodrigues
Patients infected with the Human Immunodeficiency Virus (HIV) often have opportunistic infections, among which strongyloidiasis and coccidiosis are the most common parasitic infections that aggravate their health status. This study examined the prevalence of intestinal parasites, particularly of Strongyloides stercoralis and intestinal coccidia in patients with the Human Immunodeficiency Virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) who were treated at the Specialized Assistance Service (SAE) of Jataí, State of Goiás, Brazil, and analyzed its correlation with clinical, laboratory, and socio-epidemiological parameters...
March 8, 2018: Revista do Instituto de Medicina Tropical de São Paulo
Francisca A Abanyie, Emily Valice, Kristin W Delli Carpini, Elizabeth B Gray, Isabel McAuliffe, Peter V Chin-Hong, Sukwan Handali, Susan P Montgomery, Shirish Huprikar
BACKGROUND: Targeted donor screening for strongyloidiasis performed at the time of organ procurement can prevent this life-threatening donor-derived infection. METHOD: The Association of Organ Procurement Organizations surveyed members to determine the number of U.S. organ procurement organizations (OPOs) performing donor screening for Strongyloides infection and their screening practices. RESULTS: All 58 OPOs responded to the survey. Only six (10%) currently screen donors for strongyloidiasis; most OPOs started 6-36 months before the survey, one started 6 years prior...
March 7, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
Priyanka Kanth, Kajsa Affolter
No abstract text is available yet for this article.
March 2, 2018: Clinical Gastroenterology and Hepatology
Laura M Kleinschmidt, Matthew E Kinney, Christopher S Hanley
Strongyloides nematodes have been reported in all species of great apes with orangutans ≤5 years old most susceptible to severe clinical disease. This brief communication describes the first published case of antemortem diagnosis and treatment of disseminated strongyloidiasis in a clinically affected 5-month-old Sumatran orangutan (Pongo abelii).
March 1, 2018: Journal of Medical Primatology
Angela Martinez-Perez, Silvia Roure Díez, Moncef Belhasen-Garcia, Diego Torrús-Tendero, Jose Luis Perez-Arellano, Teresa Cabezas, Cristina Soler, Marta Díaz-Menéndez, Miriam Navarro, Begoña Treviño, Fernando Salvador-Vélez
INTRODUCTION: Strongyloides stercoralis is a globally distributed nematode that causes diverse clinical symptoms in humans. Spain, once considered an endemic country, has experienced a recent increase in imported cases. The introduction of serology helps diagnosis and is currently replacing microbiological techniques in some settings, but its sensitivity is variable and can be low in immunocompromised patients. Diagnosis can only be confirmed by identification of larvae. Often, this "gold standard" can only be achieved in severe cases, such as disseminated S...
February 23, 2018: PLoS Neglected Tropical Diseases
Henrique Tomaz Gonzaga, Daniela da Silva Nunes, Vanessa da Silva Ribeiro, Nágilla Daliane Feliciano, Jair Pereira da Cunha-Junior, Julia Maria Costa-Cruz
Strongyloidiasis is an important helminthiasis affecting million people worldwide. The aim of this study was to use sodium metaperiodate (MP) treatment to immunochemically characterize Strongyloides venezuelensis filariform larvae and use MP-treated heterologous antigen to detect IgG and subclasses in serum. Samples from individuals with definitive diagnosis of strongyloidiasis (n = 50), other parasitic diseases (n = 60) and negative endemic (n = 50) were tested. TG-ROC and two-way ANOVA were applied. MP-treatment resulted on differential localization of carbohydrates at larval structure and no carbohydrate content in saline extract (SE)...
February 15, 2018: Acta Tropica
Norsyahida Arifin, Muhammad Hafiznur Yunus, Thomas J Nolan, James B Lok, Rahmah Noordin
Strongyloides stercoralis is a human parasite that can cause a long-term infection. In immunosuppressed patients, strongyloidiasis may be fatal when there is overwhelming autoinfection resulting in the migration of large numbers of larvae through many organs. Definitive diagnosis is still a challenge, and a combination of symptoms, microscopic identification, and serology test results are often used to arrive at a clinical decision. However, intermittent larval excretion, low parasite burden, and occult infections are challenges with parasitological diagnosis of infection with S...
February 12, 2018: American Journal of Tropical Medicine and Hygiene
Pedro Puerta-Alcalde, Joan Gomez-Junyent, Ana Requena-Mendez, Maria Jesús Pinazo, Miriam José Álvarez-Martínez, Natalia Rodríguez, Joaquim Gascon, Jose Muñoz
BACKGROUND: We evaluate the association between Trypanosoma cruzi infection and strongyloidiasis in a cohort of Latin American (LA) migrants screened for both infections in a non-endemic setting. METHODOLOGY: Case-control study including LA individuals who were systematically screened for T. cruzi infection and strongyloidiasis between January 2013 and April 2015. Individuals were included as cases if they had a positive serological result for Strongyloides stercoralis...
January 2018: PLoS Neglected Tropical Diseases
Hassan Tariq, Muhammad Umar Kamal, Pavithra Reddy, Bharat Bajantri, Masooma Niazi, Ajsza Matela, Cosmina Zeana, Ariyo Ihimoyan, Anil Dev, Sridhar Chilimuri
RATIONALE: Strongyloidiasis hyperinfection and disseminated disease have high mortality rates due to several complications and early detection of Strongyloides infection is therefore prudent. PATIENT CONCERNS: A 37-year-old male patient came with chronic diarrhea, intractable vomiting and was found to have hyponatremia, and anemia on the initial laboratory tests. DIAGNOSES: Further work up revealed syndrome of inappropriate antidiuretic secretion to be the cause of the hyponatremia in addition to gastrointestinal loses...
December 2017: Medicine (Baltimore)
Wanessa Trindade Clemente, Lígia Camera Pierrotti, Edson Abdala, Michele I Morris, Luiz S Azevedo, Rogelio López-Vélez, Manuel Cuenca-Estrella, Julian Torre-Cisneros, Eskild Petersen, Luis Fernando A Camargo, Alissa Jade Wright, Nicholas J Beeching, Eduardo Garcia Vilela, Guilherme Santoro-Lopes, Oscar Len, Raquel S B Stucchi, Oriol Manuel, Luciana Costa Faria, Hakan Leblebicioglu, Shirish Huprikar, Israel Molina, Paulo Henrique Orlandi Mourão, Camille N Kotton, José María Aguado
The Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America clinical practice guideline is intended to guide clinicians caring for solid-organ transplant (SOT) donors, candidates and recipients regarding infectious diseases (ID) issues related to this geographical region, mostly located in the tropics. These recommendations are based on both systematic reviews of relevant literature and expert opinion from both transplant ID and travel medicine specialists...
February 2018: Transplantation
Luis Fernando A Camargo, Nassim Kamar, Eduardo Gotuzzo, Alissa Jade Wright
No abstract text is available yet for this article.
February 2018: Transplantation
Noé Patrick M'bondoukwé, Eric Kendjo, Denise Patricia Mawili-Mboumba, Jeanne Vanessa Koumba Lengongo, Christelle Offouga Mbouoronde, Dieudonné Nkoghe, Fousseyni Touré, Marielle Karine Bouyou-Akotet
BACKGROUND: Malaria, filariasis, and intestinal parasitic infections (IPIs) are common and frequently overlap in developing countries. The prevalence and predictors of these infections were investigated in three different settlements (rural, semi-urban, and urban) of Gabon. METHODS: During cross-sectional surveys performed from September 2013 to June 2014, 451 individuals were interviewed. In addition, blood and stool samples were analysed for the presence of Plasmodium, filarial roundworm, intestinal protozoan, and helminth infections...
January 30, 2018: Infectious Diseases of Poverty
Elena Dacal, José M Saugar, Aida de Lucio, Marta Hernández-de-Mingo, Elena Robinson, Pamela C Köster, María L Aznar-Ruiz-de-Alegría, Mateu Espasa, Arlette Ninda, Javier Gandasegui, Elena Sulleiro, Milagros Moreno, Fernando Salvador, Israel Molina, Esperanza Rodríguez, David Carmena
BACKGROUND: Human infections by the gastrointestinal helminth Strongyloides stercoralis and the enteric protozoans Giardia duodenalis, Cryptosporidium spp. and Blastocystis spp. are not formally included in the list of 20 neglected tropical diseases prioritised by the World Health Organization. Although largely underdiagnosed and considered of lower public health relevance, these infections have been increasingly demonstrated to cause significant morbidity and even mortality globally, particularly among children living in resource-poor settings...
January 29, 2018: Parasites & Vectors
Gilles Eperon, Jerome Tourret, Oana Ailioaie, Luc Paris, Lucile Mercadal, Julien Mayaux, Eric Caumes, Benoit Barrou
Strongyloidiasis is caused by a soil-transmitted helminth that is endemic in tropical and subtropical countries. The parasite can complete its life cycle without leaving the host, allowing autoinfection and persistence. The risk of infection in travelers is low, but the disease may become lethal following immunosuppression. In case of solid organ transplantation, the risk of donor transmission has been suspected for several years. However, the management of live donors in this context has only recently been considered, and no guidelines exist for the management of deceased donors...
January 22, 2018: American Journal of Tropical Medicine and Hygiene
Silvia A Repetto, Paula Ruybal, Estela Batalla, Carlota López, Vanesa Fridman, Mariela Sierra, Marcelo Radisic, Pablo M Bravo, Marikena G Risso, Stella M González Cappa, Catalina D Alba Soto
Background: Strongyloides stercoralis affects 30-100 million people worldwide. The first-line therapy is ivermectin. Cure is defined as the absence of larvae by parasitological methods 1 year after treatment. To date, no longitudinal parasitological studies for longer periods of time have been conducted to confirm its cure. Here, we evaluated treatment response in long-term follow-up patients with chronic infection using parasitological and molecular methods for larvae or DNA detection...
January 19, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Scott A Weisenberg
A 74-year-old man experienced worsening asthma for several years. Oral steroids were required on multiple occasions for asthma treatment. During his steroid courses, he developed a hive-like rash, which would resolve after completion of each steroid course. He was from Romania, and had lived in the USA for many years. Laboratory testing had shown eosinophilia. He was eventually diagnosed with strongyloidiasis by serology. Treatment with ivermectin led to marked improvement but not resolution of his long-term asthma...
January 17, 2018: BMJ Case Reports
Moncef Belhassen-García, Montserrat Alonso-Sardón, Angela Martinez-Perez, Cristina Soler, Cristina Carranza-Rodriguez, José Luis Pérez-Arellano, Antonio Muro, Fernando Salvador
BACKGROUND: Strongyloides stercoralis is a parasite that causes strongyloidiasis, a neglected tropical disease. S. stercoralis is a soil-transmitted helminth that is widely distributed in tropical and subtropical regions of the world. Strongyloidiasis can occur without any symptoms or as a chronic infection characterized by mild, unspecific symptoms such as pruritus, abdominal pain or discomfort; respiratory impairment also may manifest as a potentially fatal hyperinfection or disseminated infection...
2017: PloS One
L R Bosqui, A L R Gonçalves, M R F Gonçalves-Pires, W R Pavanelli, I Conchon-Costa, J M Costa-Cruz, I N Costa
Human strongyloidiasis is caused by helminth Strongyloides stercoralis. It has a worldwide distribution, often neglected and cause of severe morbidity. The parasitological diagnosis is hindered by the low and irregular amount of larvae in feces. The goal of the present study was to detect IgG and IgG immune complex using conventional serum samples and saliva as alternative samples. We collected samples from 60 individuals, namely: group I composed of 30 healthy individuals; and group II composed of 30 individuals eliminating S...
December 14, 2017: Parasitology
Laura M Filkins, David C Gaston, Blaine Mathison, Timothy Smith, Marc Roger Couturier, Ryan D Murphy, Claire Ciarkowski, Kimberly E Hanson, Paloma F Cariello
We report the rare finding of Strongyloides stercoralis rhabditiform larvae in biliary fluid, here associated with cholecystitis and near total portal vein thrombosis. The role of S. stercoralis leading to atypical clinical presentations and difficulty diagnosing strongyloidiasis in such patients with appropriate geographic exposure is discussed.
2017: Open Forum Infectious Diseases
M L S Silva, E J Inês, J N Souza, A B S Souza, V M S Dias, L N Oliveira, C M Guimarães, E R Menezes, L G Barbosa, M C M Alves, M C A Teixeira, N M Soares
Alcoholic patients are more susceptible to Strongyloides stercoralis infection. The chronic use of alcohol raises the levels of endogenous corticosteroids, which regulates the development of larvae and stimulates the differentiation of rhabditiform into infective filariform larvae, thus inducing internal autoinfection. Therefore, early diagnosis is important to prevent severe strongyloidiasis. The aim of this study was to evaluate the efficacy of parasitological methods, according to the parasite load and the number of stool samples, for diagnosis of S...
November 28, 2017: Journal of Helminthology
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