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Strongyloidiasis

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https://www.readbyqxmd.com/read/28929562/seroepidemiological-trend-of-strongyloidiasis-in-the-bolivian-chaco-1987-2013-in-the-absence-of-disease-specific-control-measures
#1
Michele Spinicci, Fabio Macchioni, Antonia Mantella, Simona Gabrielli, Mimmo Roselli, David Rojo Mayaregua, Joaquín Monasterio Pinckert, Herlan Gamboa Barahona, Grover Adolfo Paredes, Percy Halkyer, Gabriella Cancrini, Piero Olliaro, Antonio Montresor, Alessandro Bartoloni
OBJECTIVES: The prevalence of Strongyloides stercoralis infections is grossly underestimated because infections go mostly undetected, though they can persist for a lifetime due to the auto-infective cycle. In the Bolivian Chaco, the prevalence of soil-transmitted nematodes dropped dramatically in the past 25 years, but the mebendazole used for preventive chemotherapy has no effect on S. stercoralis. Meanwhile, the prevalence of intestinal protozoan infections remains unchanged. We compared S...
September 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28923008/an-eleven-year-retrospective-hospital-based-study-of-epidemiological-data-regarding-human-strongyloidiasis-in-northeast-thailand
#2
Thidarat K Prasongdee, Pokkamol Laoraksawong, Wanida Kanarkard, Ratthaphol Kraiklang, Kraisit Sathapornworachai, Sureeporn Naonongwai, Porntip Laummaunwai, Oranuch Sanpool, Pewpan M Intapan, Wanchai Maleewong
BACKGROUND: Human strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic prevalence regarding strongyloidiasis in northeast Thailand through a hospital-based study. METHODS: Patients' demographic data and the results of stool examinations conducted using the formalin ethyl acetate concentration technique were collected from the parasitology laboratory records at Srinagarind Hospital in Khon Kaen, Thailand...
September 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28893741/prevention-and-assessment-of-infectious-diseases-among-children-and-adult-migrants-arriving-to-the-european-union-european-economic-association-a-protocol-for-a-suite-of-systematic-reviews-for-public-health-and-health-systems
#3
Kevin Pottie, Alain D Mayhew, Rachael L Morton, Christina Greenaway, Elie A Akl, Prinon Rahman, Dominik Zenner, Manish Pareek, Peter Tugwell, Vivian Welch, Joerg Meerpohl, Pablo Alonso-Coello, Charles Hui, Beverley-Ann Biggs, Ana Requena-Méndez, Eric Agbata, Teymur Noori, Holger J Schünemann
INTRODUCTION: The European Centre for Disease Prevention and Control is developing evidence-based guidance for voluntary screening, treatment and vaccine prevention of infectious diseases for newly arriving migrants to the European Union/European Economic Area. The objective of this systematic review protocol is to guide the identification, appraisal and synthesis of the best available evidence on prevention and assessment of the following priority infectious diseases: tuberculosis, HIV, hepatitis B, hepatitis C, measles, mumps, rubella, diphtheria, tetanus, pertussis, poliomyelitis (polio), Haemophilus influenza disease, strongyloidiasis and schistosomiasis...
September 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28879209/colorectal-cancer-associated-with-strongyloides-stercoralis-colitis
#4
Carmine Catalano, Joshua Aron, Raghav Bansal, Anatoly Leytin
Strongyloides stercoralis colitis is a severe but easily curable disease with a high mortality rate if left untreated. Strongyloidiasis can persist up to several decades and may lead to a chronic colitis similar to that seen in inflammatory bowel disease (IBD), and the two are often confused. Chronic colitis from IBD is associated with an increased risk of colorectal cancer, so it is plausible that chronic colitis from strongyloidiasis may carry a similar risk. Our case report associates chronic Strongyloides colitis and colorectal cancer...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28869694/strongyloides-stercoralis-infection-increases-the-likelihood-to-detect-trypanosoma-cruzi-dna-in-peripheral-blood-in-chagas-disease-patients
#5
Fernando Salvador, Elena Sulleiro, Maria Piron, Adrián Sánchez-Montalvá, Silvia Sauleda, Daniel Molina-Morant, Zaira Moure, Israel Molina
OBJECTIVES: In a previous study performed by our group, S. stercoralis infection in Chagas disease patients was associated with higher proportion of Trypanosoma cruzi DNA detection in peripheral blood. The aim of the study was to confirm this association in a larger cohort of patients. METHODS: Cross-sectional study of all Chagas disease patients diagnosed from 2005 to 2015 during blood donation at the Catalan Blood Bank. Demographic data and T. cruzi RT-PCR were collected...
September 4, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28842188/the-changing-aetiology-of-eosinophilia-in-migrants-and-returning-travellers-in-the-hospital-for-tropical-diseases-london-2002-2015-an-observational-study
#6
Jessica Barrett, Clare E Warrell, Liana Macpherson, Julie Watson, Patricia Lowe, Margaret Armstrong, Christopher J M Whitty
INTRODUCTION: Determining the cause of eosinophilia in patients returning from the tropics continues to present a diagnostic challenge. The history, symptoms and degree of eosinophilia are often poor predictors of eventual diagnosis, but helminths are an important cause. The current British Infection Association recommendations use travel history to guide investigation of eosinophilia. However the global burden of helminth disease and travel patterns have changed over the last 3 decades and guidelines based on previous epidemiology need to be reviewed in the light of current data...
August 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28837662/mass-drug-administration-for-the-prevention-human-strongyloidiasis-should-consider-concomitant-treatment-of-dogs
#7
Meruyert Beknazarova, Harriet Whiley, Kirstin Ross
No abstract text is available yet for this article.
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28793306/different-but-overlapping-populations-of-strongyloides-stercoralis-in-dogs-and-humans-dogs-as-a-possible-source-for-zoonotic-strongyloidiasis
#8
Tegegn G Jaleta, Siyu Zhou, Felix M Bemm, Fabian Schär, Virak Khieu, Sinuon Muth, Peter Odermatt, James B Lok, Adrian Streit
Strongyloidiasis is a much-neglected soil born helminthiasis caused by the nematode Strongyloides stercoralis. Human derived S. stercoralis can be maintained in dogs in the laboratory and this parasite has been reported to also occur in dogs in the wild. Some authors have considered strongyloidiasis a zoonotic disease while others have argued that the two hosts carry host specialized populations of S. stercoralis and that dogs play a minor role, if any, as a reservoir for zoonotic S. stercoralis infections of humans...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28749768/evidence-based-guidelines-for-screening-and-management-of-strongyloidiasis-in-non-endemic-countries
#9
Ana Requena-Méndez, Dora Buonfrate, Joan Gomez-Junyent, Lorenzo Zammarchi, Zeno Bisoffi, José Muñoz
Strongyloidiasis is an intestinal parasitic infection becoming increasingly important outside endemic areas, not only because of the high prevalence found in migrant populations, but also because immunosuppressed patients may suffer a potentially fatal disseminated disease. The aim of these guidelines is to provide evidence-based guidance for screening and treatment of strongyloidiasis in non-endemic areas. A panel of experts focused on three main clinical questions (who should be screened and how, how to treat), and reviewed pertinent literature available in international databases of medical literature and in documents released by relevant organizations/societies...
July 24, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28731999/-duodenal-linphoma-asociated-to-strongyloides-stercoralis-infection-two-types-of-htlv-1-infection
#10
Julissa Guevara Miranda, Patricia Guzmán Rojas, Jorge Espinoza-Ríos, Fernando Mejía Cordero
Infection by the Human T- Lymphotropic virus I (HTLV-1) causes Adult T cell Leukemia-lymphoma (ATLL), being the duodenal involvement rare. Commonly, patients co-infected with HTLV-1 and Strongyloides stercoralis are seen due to the lack of TH2 response found on these patients. We describe a 48-year- old woman, from the jungle of Peru, with a family history of HTLV-1 infection, who presented with a History of chronic diarrhea and weight loss. HTLV-1 infection with ATLL and strongyloidiasis were diagnosed. Ivermectin treatment and chemotherapy were initiated, being stabilized, and discharged...
April 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28728589/occurrence-of-strongyloidiasis-in-privately-owned-and-sheltered-dogs-clinical-presentation-and-treatment-outcome
#11
Paola Paradies, Fabrizio Iarussi, Mariateresa Sasanelli, Antonio Capogna, Riccardo Paolo Lia, Daniele Zucca, Beatrice Greco, Cinzia Cantacessi, Domenico Otranto
BACKGROUND: The increasing number of reports of human infections by Strongyloides stercoralis from a range of European countries over the last 20 years has spurred the interest of the scientific community towards this parasite and, in particular, towards the role that infections of canine hosts may play in the epidemiology of human disease. Data on the epidemiology of canine strongyloidiasis is currently limited, most likely because of the inherent limitations of current diagnostic methods...
July 20, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28721104/case-report-of-a-computerized-tomography-sign-in-strongyloides-stercoralis-infection
#12
Sandeep Yerra, Pradeep Yarra
This is a case of strongyloidiasis showing colon enhancement on a computerized tomography (CT) scan. The patient presented with chief complaints of diarrhea and abdominal pain. She gave a history of recent travel to El Salvador and her stool was positive for Strongyloides stercoralis. A CT scan revealed a circumferential enhancement of the sigmoid colon. This CT sign was unusual in strongyloidiasis and when combined with the symptoms, caused us to rule out inflammatory bowel disease and shock bowel. Stool examination revealed ova and parasites of Strongyloides stercoralis...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28676845/th2-1-hybrid-cells-occurring-in-murine-and-human-strongyloidiasis-share-effector-functions-of-th1-cells
#13
Cristin N Bock, Subash Babu, Minka Breloer, Anuradha Rajamanickam, Yukhti Boothra, Marie-Luise Brunn, Anja A Kühl, Roswitha Merle, Max Löhning, Susanne Hartmann, Sebastian Rausch
Infections by the soil-transmitted threadworm Strongyloides stercoralis affect 30-100 million people worldwide, predominantly in tropic and sub-tropic regions. Here we assessed the T helper cell phenotypes in threadworm-infected patients and experimental murine infections with focus on CD4(+) T cells co-expressing markers of Th2 and Th1 differentiation. We show that mice infected with the close relative S. ratti generate strong Th2 responses characterized by the expansion of CD4(+) GATA-3(+) cells expressing IL-4/-5/-13 in blood, spleen, gut-draining lymph nodes, lung and gut tissue...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28670749/the-severely-under-recognized-public-health-risk-of-strongyloidiasis-in-north-american-cities-a-one-health-approach
#14
REVIEW
S Jariwala, L Redding, D Hewitt
Strongyloides and other soil-transmitted helminths represent a severely under-recognized zoonotic public health risk, especially in North American cities. They are present throughout North America, including in urban areas, causing morbidity and mortality in human and non-human animals. Epidemiological "masking" of strongyloidiasis due to overlapping symptoms with other systemic diseases, including allergies, and diagnostic limitations complicate our understanding of the epidemiological extent of this disease, and auto-infection allows long-term persistence of individual infections...
July 2, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28641722/novel-findings-in-hiv-immune-reconstitution-disease-and-strongyloides-stercoralis-infection
#15
REVIEW
Roberto G Aru, Benjamin M Chilcutt, Saira Butt, Richard D deShazo
We report the successful treatment of an HIV-infected patient with progressive strongyloidiasis as a component of immune reconstitution disease and a review of the literature on this topic. In our experience, pre- and post-antiretroviral therapy intestinal biopsies support a novel mechanism of immune reconstitution disease to Strongyloides stercoralis. We conclude that extended, dual antihelminthic therapy and temporary discontinuation of antiretroviral therapy may be effective in similar patients.
June 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28618740/screening-of-immunocompromised-patients-at-risk-of-strongyloidiasis-in-western-turkey-using-elisa-and-real-time-pcr
#16
Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyin Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyin Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan
BACKGROUND/AIM: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey. MATERIALS AND METHODS: Serum and stool samples were collected from 108 patients (25.9% of them were chronic renal failure and 74.1% were renal transplantation patients) who were admitted to Ege University Medical School in İzmir, located in western Turkey...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28562417/strongyloides-stercoralis-in-solid-organ-transplantation-early-diagnosis-gets-the-worm
#17
Constance M Mobley, Atiya Dhala, Rafik Mark Ghobrial
PURPOSE OF REVIEW: Strongyloidiasis is a parasitic infection affecting millions of people worldwide. Complications of infection are strongly associated with alcoholism, immunosuppression, and organ transplantation. Delayed diagnosis results in hyperinfection syndrome and disseminated strongyloidiasis leading to mortality rates approaching 80%. Early detection, and prevention of infection and transmission are key to diminish this illness. RECENT FINDINGS: In this review, we cover the basic concepts in immunity, immunosuppression, and disorder necessary for understanding the infectious syndromes associated with Strongyloides stercoralis infection...
August 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28508164/viability-of-strongyloides-venezuelensis-eggs-and-larvae-in-vermiculite-containing-the-fungus-duddingtonia-flagrans
#18
Laryssa Pinheiro Costa Silva, Carolina Magri Ferraz, Anderson Rocha Aguiar, Jackson Victor Araújo, Steveen Rios Ribeiro, Débora Goldner Rossi, Luanderson Queiroz Mendes, Fausto Edmundo Lima Pereira, Narcisa Imaculada Brant Moreira, Fabio Ribeiro Braga
Strongyloidiasis is the most clinically important disease among the infections caused by geohelminths, seeing that this parasite can cause autoinfection. The use of nematophagous fungi like Duddingtonia flagrans, that have predation action on eggs and infecciososas forms of helminths, emerges as an alternative method for environmental control. For this reason, analyzing the viability of larvae and eggs of Strongyloides venezuelensis and the action of Duddingtonia flagrans AC001 in vermiculite, as well as the action of the nematophagous fungi in different growth stages, is important to elaborate and define the best culture conditions that favor the activity of the fungus...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28493000/serological-and-molecular-tests-for-the-diagnosis-of-strongyloides-stercoralis-infection-in-dogs
#19
Dora Buonfrate, Paola Paradies, Fabrizio Iarussi, Fabio Formenti, Francesca Perandin, Domenico Otranto, Zeno Bisoffi
Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. In this study, two serologic assays and a real-time PCR (RT-PCR), routinely used for the diagnosis of strongyloidiasis in humans, have been tested for the diagnosis in dogs. Five dogs living in the same kennel in Bari, southern Italy, were diagnosed with S...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28469498/twenty-five-years-of-chronic-strongyloidiasis-in-an-immigrant
#20
Kalambay N Junior, Rehana Zaman, Mohammed H Zaman, Taufiq Zaman
Chronic strongyloidiasis is an infection of the tropical regions, caused by the nematode Strongyloides stercoralis. In the United States, patients are typically immigrants. The very long asymptomatic phase followed by the clinical presentation of the disease mimics asthma, chronic obstructive pulmonary disease (COPD), or inflammatory bowel disease (IBD) as in this case report. The inconsistency of eosinophilia and the low sensitivity of microscopic stool examination make chronic strongyloidiasis a disease that is frequently misdiagnosed in the United States...
2017: Clinical Medicine Insights. Case Reports
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