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Strongyloidiasis

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https://www.readbyqxmd.com/read/28618740/screening-of-immunocompromised-patients-at-risk-of-strongyloidiasis-in-western-turkey-using-elisa-and-real-time-pcr
#1
Esra Erdem Kivrak, Esra Atalay Şahar, Hüseyin Can, Mert Döşkaya, Mümtaz Yilmaz, Hüsnü Pullukçu, Ayşe Caner, Hüseyin Töz, Adnan Yüksel Gürüz, Meltem Işikgöz Taşbakan
BACKGROUND/AIM: Strongyloides stercoralis causes life-threatening hyperinfection or disseminated strongyloidiasis in immunocompromised patients such as HIV-positive, organ transplantation, and cancer patients. This study investigated the presence of strongyloidiasis in immunocompromised patients for the first time in Turkey. MATERIALS AND METHODS: Serum and stool samples were collected from 108 patients (25.9% of them were chronic renal failure and 74.1% were renal transplantation patients) who were admitted to Ege University Medical School in İzmir, located in western Turkey...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28562417/strongyloides-stercoralis-in-solid-organ-transplantation-early-diagnosis-gets-the-worm
#2
Constance M Mobley, Atiya Dhala, Rafik Mark Ghobrial
PURPOSE OF REVIEW: Strongyloidiasis is a parasitic infection affecting millions of people worldwide. Complications of infection are strongly associated with alcoholism, immunosuppression, and organ transplantation. Delayed diagnosis results in hyperinfection syndrome and disseminated strongyloidiasis leading to mortality rates approaching 80%. Early detection, and prevention of infection and transmission are key to diminish this illness. RECENT FINDINGS: In this review, we cover the basic concepts in immunity, immunosuppression, and disorder necessary for understanding the infectious syndromes associated with Strongyloides stercoralis infection...
May 29, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28508164/viability-of-strongyloides-venezuelensis-eggs-and-larvae-in-vermiculite-containing-the-fungus-duddingtonia-flagrans
#3
Laryssa Pinheiro Costa Silva, Carolina Magri Ferraz, Anderson Rocha Aguiar, Jackson Victor Araújo, Steveen Rios Ribeiro, Débora Goldner Rossi, Luanderson Queiroz Mendes, Fausto Edmundo Lima Pereira, Narcisa Imaculada Brant Moreira, Fabio Ribeiro Braga
Strongyloidiasis is the most clinically important disease among the infections caused by geohelminths, seeing that this parasite can cause autoinfection. The use of nematophagous fungi like Duddingtonia flagrans, that have predation action on eggs and infecciososas forms of helminths, emerges as an alternative method for environmental control. For this reason, analyzing the viability of larvae and eggs of Strongyloides venezuelensis and the action of Duddingtonia flagrans AC001 in vermiculite, as well as the action of the nematophagous fungi in different growth stages, is important to elaborate and define the best culture conditions that favor the activity of the fungus...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28493000/serological-and-molecular-tests-for-the-diagnosis-of-strongyloides-stercoralis-infection-in-dogs
#4
Dora Buonfrate, Paola Paradies, Fabrizio Iarussi, Fabio Formenti, Francesca Perandin, Domenico Otranto, Zeno Bisoffi
Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. In this study, two serologic assays and a real-time PCR (RT-PCR), routinely used for the diagnosis of strongyloidiasis in humans, have been tested for the diagnosis in dogs. Five dogs living in the same kennel in Bari, southern Italy, were diagnosed with S...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28469498/twenty-five-years-of-chronic-strongyloidiasis-in-an-immigrant
#5
Kalambay N Junior, Rehana Zaman, Mohammed H Zaman, Taufiq Zaman
Chronic strongyloidiasis is an infection of the tropical regions, caused by the nematode Strongyloides stercoralis. In the United States, patients are typically immigrants. The very long asymptomatic phase followed by the clinical presentation of the disease mimics asthma, chronic obstructive pulmonary disease (COPD), or inflammatory bowel disease (IBD) as in this case report. The inconsistency of eosinophilia and the low sensitivity of microscopic stool examination make chronic strongyloidiasis a disease that is frequently misdiagnosed in the United States...
2017: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/28464844/pulmonary-strongyloidiasis-assessment-between-manifestation-and-radiological-findings-in-16-severe-strongyloidiasis-cases
#6
Daijiro Nabeya, Shusaku Haranaga, Gretchen Lynn Parrott, Takeshi Kinjo, Saifun Nahar, Teruhisa Tanaka, Tetsuo Hirata, Akira Hokama, Masao Tateyama, Jiro Fujita
BACKGROUND: Strongyloidiasis is a chronic parasitic infection caused by Strongyloides stercoralis. Severe cases such as, hyperinfection syndrome (HS) and disseminated strongyloidiasis (DS), can involve pulmonary manifestations. These manifestations frequently aid the diagnosis of strongyloidiasis. Here, we present the pulmonary manifestations and radiological findings of severe strongyloidiasis. METHODS: From January 2004 to December 2014, all patients diagnosed with severe strongyloidiasis at the University of the Ryukyus Hospital or affiliated hospitals in Okinawa, Japan, were included in this retrospective study...
May 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28455628/identification-of-antigenic-proteins-in-strongyloides-stercoralis-by-proteomic-analysis
#7
Rutchanee Rodpai, Pewpan M Intapan, Tongjit Thanchomnang, Oranuch Sanpool, Penchom Janwan, Porntip Laummaunwai, Chaisiri Wongkham, Tonkla Insawang, Wanchai Maleewong
Strongyloides stercoralis is an intestinal helminth that infects people worldwide. Hyperinfection or disseminated human strongyloidiasis can involve vital organs, leading to lethal outcomes. We analyzed immunoproteomics of antigenic spots, derived from S. stercoralis third-stage larvae and reacted with human strongyloidiasis sera, by two-dimensional gel electrophoresis and immunoblotting. Of 26 excised antigenic spots analyzed by liquid chromatography-electrospray ionization-tandem mass spectrometry, 20 proteins were identified...
April 29, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28428660/intestinal-strongyloidiasis-radiological-findings-that-support-the-diagnosis
#8
José Henrique Frota Júnior, Marcos Antônio Haddad Pereira, Paulo Gustavo Maciel Lopes, Leandro Accardo Matos, Giuseppe D'Ippolito
No abstract text is available yet for this article.
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28414672/a-strong-and-fortuitous-case-of-dyspnea
#9
R Hammer, M Sciaudone
CASE: A 48 year-old man with no past medical history was sent to our emergency department (ED); from a primary care clinic for hypertensive urgency of 200/130. The man reported an intermittent non-productive cough of approximately one year's duration and worsening dyspnea on exertion and orthopnea over the last month with lower extremity swelling. Of note, he emigrated from Honduras twenty years ago. Blood pressure normalized with administration of Lasix in the ED. Physical exam revealed rales in lung bases bilaterally, jugular venous distension, lower extremity pitting edema with serpiginous patches of erythema and excoriation, and a cardiac gallop...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28394981/-clinical-and-epidemiological-characteristics-of-strongyloidiasis-in-patients-with-comorbidities
#10
Amanda Regueira Fernandes, Sebastián Romero, Paula Fernanda Alcântara de Souza Melo, Paulo Sérgio Ramos Araújo, Oscar Bottasso, Abraham Rocha, Eduardo Brandão
The strongyloidiasis is a parasitic disease that poses as a serious public health problem, mainly in tropical and subtropical countries. Over the years, some conditions, such as advances in corticosteroid treatment and immunosuppressive diseases, have improved not only the increase in cases of strongyloidiasis, but also the emergence of severe forms of the disease and / or deaths. For these reasons, the objective of this study is to make a critical analysis of the occurrence of strongyloidiasis in patients with comorbidities, describing clinical and epidemiological characteristics associated with these diseases that can highlight the importance of monitoring this parasitosis in most susceptible groups...
February 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28380118/in-vitro-efficacy-of-latex-and-purified-papain-from-carica-papaya-against-strongyloides-venezuelensis-eggs-and-larvae
#11
Dayane Moraes, Marcelo Arantes Levenhagen, Julia Maria Costa-Cruz, Antônio Paulino da Costa, Rosângela Maria Rodrigues
Latex from Carica papaya is rich in bioactive compounds, especially papain, which may help to control parasitic diseases. This study evaluated the efficacy of latex from C. papaya and purified papain against Strongyloides venezuelensis. The Egg Hatching Test (EHT) and the Larval Motility Test (LMT) using fresh and frozen latex (250mg/mL), lyophilized latex (34mg/mL), and purified papain (2.8 mg/mL) were performed. Albendazole (0.025 mg/mL) and ivermectin (316 ppm) were used as positive controls. EHT and LMT were carried out through the incubation of each solution with S...
April 3, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28331839/enterococcal-meningitis-in-association-with-strongyloides-hyperinfection-syndrome
#12
Kalpesh S Sukhwani, Nitin Bansal, Mamta Soni, Anand Ramamurthy, Ram Gopalakrishnan
INTRODUCTION: Strongyloidiasis can cause hyperinfection or disseminated infection in an immunocompromised host, and is an important factor linked to enterococcal bacteremia and meningitis. CASE REPORTS: We report two cases highlighting the importance of suspecting Strongyloides hyperinfection syndrome in patients with enterococcal meningitis. CONCLUSION: Our cases highlight the importance of suspecting Strongyloides hyperinfection syndrome in cases of community acquired enterococcal bacteremia and meningitis...
March 2017: Germs
https://www.readbyqxmd.com/read/28261873/purpuric-lesion-in-an-immunocompromised-patient-a-presentation-of-disseminated-strongyloidiasis
#13
LETTER
A D da Silva Citrin, J A Guzmán, J Barros, C D Machado-Filho
No abstract text is available yet for this article.
March 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28259548/seroprevalence-of-five-neglected-parasitic-diseases-among-immigrants-accessing-five-infectious-and-tropical-diseases-units-in-italy-a-cross-sectional-study
#14
G Martelli, C Di Girolamo, L Zammarchi, A Angheben, M Morandi, S Tais, M Degani, I El Hamad, S Caligaris, A Ciannameo, E Grilli, L Urbinati, G B Monteiro, C Scarcella, N Petrosillo, M Digaetano, L Rabbi, N Bazzanini, F Cacciatore, B L Marta, M L Moro, A Bartoloni, P Viale, G Verucchi
OBJECTIVE: This multicentre cross-sectional study aims to estimate the prevalence of five neglected tropical diseases (Chagas disease, filariasis, schistosomiasis, strongyloidiasis and toxocariasis) among immigrants accessing health care facilities in five Italian cities (Bologna, Brescia, Florence, Rome, Verona). METHODS: Individuals underwent a different set of serological tests, according to country of origin and presence of eosinophilia. Seropositive patients were treated and further followed up...
March 1, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28210503/strongyloidiasis-current-status-with-emphasis-in-diagnosis-and-drug-research
#15
REVIEW
Tiago Mendes, Karen Minori, Marlene Ueta, Danilo Ciccone Miguel, Silmara Marques Allegretti
Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, since there are no gold standard diagnostic techniques, and the ones used have problems associated with sensitivity, resulting in false negatives...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28178298/the-impact-of-prenatal-exposure-to-parasitic-infections-and-to-anthelminthic-treatment-on-antibody-responses-to-routine-immunisations-given-in-infancy-secondary-analysis-of-a-randomised-controlled-trial
#16
Stephen Nash, Alexander J Mentzer, Swaib A Lule, Dennison Kizito, Gaby Smits, Fiona R M van der Klis, Alison M Elliott
BACKGROUND: Chronic parasitic infections are associated with active immunomodulation which may include by-stander effects on unrelated antigens. It has been suggested that pre-natal exposure to parasitic infections in the mother impacts immunological development in the fetus and hence the offspring's response to vaccines, and that control of parasitic infection among pregnant women will therefore be beneficial. METHODOLOGY/PRINCIPAL FINDINGS: We used new data from the Entebbe Mother and Baby Study, a trial of anthelminthic treatment during pregnancy conducted in Uganda, to further investigate this hypothesis...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28139968/disseminated-strongyloidiasis-and-concomitant-aspergillus-infection-with-central-nervous-system-involvement
#17
Hannah Wang, Richard A Prayson
No abstract text is available yet for this article.
January 30, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/28127364/prevalence-of-strongyloides-stercoralis-and-other-intestinal-parasites-among-institutionalized-mentally-disabled-individuals-in-rasht-northern-iran
#18
Amin Saeidinia, Ilnaz Tavakoli, Mohammad Reza Naghipour, Behnaz Rahmati, Hossein Ghavami Lahiji, Omid Salkhori, Keyhan Ashrafi
BACKGROUND: We aimed to determine the status of strongyloidiasis in mentally disabled population in the institutional places in Rasht City, the capital of Guilan Province, northern Iran. METHODS: This cross-sectional study was conducted in 8 institutions for mentally retarded population in Rasht in 2013. Before collecting the samples, a questionnaire was filled out for each participant by an expert person. A single stool sample was obtained from each of the 173 subjects and examined using direct wet mount, formalin-ether concentration technique and agar plate culture method...
October 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28127349/disseminated-strongyloidiasis-in-an-immunodeficient-patient-pemphigus-vulgaris-due-to-corticosteroid-therapy-a-case-report
#19
Mohsen Najjari, Mohammad Ebrahimipour, Amir Kaheh, Mohammadreza Karimazar
Strongyloidiasis is a frequent misdiagnosed parasitic infection in the world that caused by Strongyloides stercoralis. In Iran, the disease is predominantly reported from warm and humid climate provinces. The patient was a 54-yr-old man, originated from Khuzestan Province with a history of pemphigus and diabetes that was treated with high-dose of corticosteroid drugs before admission in a non-private hospital in Shiraz, Iran in 2014. After different primary diagnosis and administrating of several drugs, endoscopy and histopatholgical biopsy revealed a massive S...
July 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28124134/diagnosis-of-strongyloides-stercoralis-by-morphological-characteristics-combine-with-molecular-biological-methods
#20
Li-Fu Wang, Lian Xu, Shi-Qi Luo, Hui Xie, Wei Chen, Zhong-Dao Wu, Xi Sun
Strongyloidiasis is one of the neglected tropical diseases caused by infection with the nematode Strongyloides genus and distributed worldwide. Strongyloidiasis can be fatal in immunosuppressed patients induced hyperinfection or disseminated strongyloidiasis. Unfortunately, until now, due to the unspecific clinical symptom in infected individuals and the low sensitivity diagnosis of strongyloidiasis, many patients were misdiagnosed every year. Furthermore, the larvae of the Strongyloides stercoralis (S. stercoralis) is similar to other nematodes such as hookworm, Trichostrongylus increased the difficulty of diagnosis...
January 26, 2017: Parasitology Research
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