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https://www.readbyqxmd.com/read/28926103/fam20c-regulates-osteoblast-behaviors-and-intracellular-signaling-pathways-in-a-cell-autonomous-manner
#1
Chao Liu, Hua Zhang, Priyam Jani, Xiaofang Wang, Yongbo Lu, Nan Li, Jing Xiao, Chunlin Qin
Recent studies indicate that Family with sequence similarity 20 member C (FAM20C) catalyzes the phosphorylation of secreted proteins, and participates in a variety of biological processes, including cell proliferation, migration, mineralization and phosphate homeostasis. To explore the local influences of FAM20C on osteoblast, Fam20c-deficient osteoblasts were generated by treating the immortalized Fam20c(f/f) osteoblasts with CMV-Cre-IRES-EGFP lentivirus. Compared with the normal Fam20c(f/f) osteoblasts, the expression of Bone sialoprotein (Bsp), Osteocalcin (Ocn), Fibroblast growth factor 23 (Fgf23) and transcription factors that promote osteoblast maturation were up-regulated in the Fam20c-deficient osteoblasts...
September 19, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28925491/corrosion-behavior-of-dental-implants-immersed-into-human-saliva-preliminary-results-of-an-in-vitro-study
#2
M Barbieri, F Mencio, P Papi, D Rosella, S Di Carlo, T Valente, G Pompa
OBJECTIVE: Over the years, different implant surfaces have been used to try to maximize bone to implant contact. The aim of this study was to compare levels of metallic ions and particles dissolution collected from two different dental implants surfaces immersed into human saliva. PATIENTS AND METHODS: A total of 60 dental implants were tested. Group A: sanded with aluminium oxide medium grade particles and acid-etched; Group B: micro-sanded with calcium phosphate powders and acid-etched...
August 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#3
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28916163/effects-of-small-grit-grinding-and-glazing-on-mechanical-behaviors-and-ageing-resistance-of-a-super-translucent-dental-zirconia
#4
Xuan Lai, Wenjie Si, Danyu Jiang, Ting Sun, Longquan Shao, Bin Deng
OBJECTIVES: The purpose of this study is to elucidate the effects of small-grit grinding on the mechanical behaviors and ageing resistance of a super-translucent dental zirconia and to investigate the necessity of glazing for the small-grit ground zirconia. METHODS: Small-grit grinding was performed using two kinds of silicon carbide abrasive papers. The control group received no grinding. The unground surfaces and the ground surfaces were glazed by an experienced dental technician...
September 12, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28915303/prevalence-of-functional-dentition-in-a-group-of-mexican-adult-males
#5
Mirna Minaya-Sánchez, Carlo Eduardo Medina-Solís, Juan Fernando Casanova-Rosado, Ana Alicia Vallejos-Sánchez, Alejandro José Casanova-Rosado, María de Lourdes Márquez-Corona, Martha Mendoza-Rodríguez, Gerardo Maupomé
OBJECTIVE: To determine the prevalence of functional dentition and associated periodontal variables in a sample of Mexican adult males. METHODS: A cross-sectional study of 161 policemen in Campeche, Mexico, was carried out. A clinical examination using an electronic probe was used to collect variables (dental plaque, periodontal pockets, gingival recession, suppuration, and bleeding on probing) on 6 periodontal sites (a maximum of 168 sites, excluding third molars)...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28914948/nanotopography-mediated-osteogenic-differentiation-of-human-dental-pulp-derived-stem-cells
#6
Akash Bachhuka, Bahman Delalat, Soraya Rasi Ghaemi, Stan Gronthos, Nicolas H Voelcker, Krasimir Vasilev
Advanced medical devices, treatments and therapies demand an understanding of the role of interfacial properties on the cellular response. This is particularly important in the emerging fields of cell therapies and tissue regeneration. In this study, we evaluate the role of surface nanotopography on the fate of human dental pulp derived stem cells (hDPSC). These stem cells have attracted interest because of their capacity to differentiate to a range of useful lineages but are relatively easy to isolate. We generated and utilized density gradients of gold nanoparticles which allowed us to examine, on a single substrate, the influence of nanofeature density and size on stem cell behavior...
September 15, 2017: Nanoscale
https://www.readbyqxmd.com/read/28913331/health-effects-and-public-health-concerns-of-energy-drink-consumption-in-the-united-states-a-mini-review
#7
REVIEW
Laila Al-Shaar, Kelsey Vercammen, Chang Lu, Scott Richardson, Martha Tamez, Josiemer Mattei
As energy drink consumption continues to grow worldwide and within the United States, it is important to critically examine the nutritional content and effects on population health of these beverages. This mini-review summarizes the current scientific evidence on health consequences from energy drink consumption, presents relevant public health challenges, and proposes recommendations to mitigate these issues. Emerging evidence has linked energy drink consumption with a number of negative health consequences such as risk-seeking behaviors, poor mental health, adverse cardiovascular effects, and metabolic, renal, or dental conditions...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28905475/evaluation-of-volumetric-dimensional-changes-in-posterior-extraction-sites-with-and-without-arp-using-a-novel-imaging-device
#8
Carolina Sbordone, Paolo Toti, Ranieri Martuscelli, Franco Guidetti, Massimo Porzio, Ludovico Sbordone
BACKGROUND: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes. PURPOSE: The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering. MATERIALS AND METHODS: In the present controlled study, patients subjected to single-tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral (bbm), and naturally healing sockets (nat)...
September 14, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28904966/the-effect-of-oral-dexmedetomidine-premedication-on-preoperative-cooperation-and-emergence-delirium-in-children-undergoing-dental-procedures
#9
Sultan Keles, Ozlem Kocaturk
INTRODUCTION: The aim of this study was to detect the effect of 1 μg/kg of oral dexmedetomidine (DEX) as premedication among children undergoing dental procedures. MATERIALS AND METHODS: The study involved 100 children between 2 and 6 years of age, ASA I, who underwent full-mouth dental rehabilitation. The DEX group (n = 50) received 1 μg/kg DEX in apple juice, and the control group (n = 50) received only apple juice. The patients' scores on the Ramsay Sedation Scale (RSS), parental separation anxiety scale, mask acceptance scale, and pediatric anesthesia emergence delirium scale (PAEDS) and hemodynamic parameters were recorded...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28902238/dental-ceramics-a-review-of-new-materials-and-processing-methods
#10
Lucas Hian da Silva, Erick de Lima, Ranulfo Benedito de Paula Miranda, Stéphanie Soares Favero, Ulrich Lohbauer, Paulo Francisco Cesar
The evolution of computerized systems for the production of dental restorations associated to the development of novel microstructures for ceramic materials has caused an important change in the clinical workflow for dentists and technicians, as well as in the treatment options offered to patients. New microstructures have also been developed by the industry in order to offer ceramic and composite materials with optimized properties, i.e., good mechanical properties, appropriate wear behavior and acceptable aesthetic characteristics...
August 28, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28899616/risk-factors-for-dental-problems-recommendations-for-oral-health-in-infancy
#11
REVIEW
Yvonne Wagner, Roswitha Heinrich-Weltzien
Primary care providers, gynaecologists and paediatricians have to be aware of the importance of oral health in infancy and possible consequences for child's development, growth, health and quality of life. Oral diseases, particularly dental caries, developmental defects of the dental tissues and periodontal or orthodontic issues have a complex and interrelated aetiology with common, primarily behavioral based risk factors. A sugar-rich diet is the key risk factor with detrimental consequences for general and oral health, particularly in combination with an insufficient oral hygiene...
September 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/28898732/poly-n-isopropylacrylamide-hydroxyapatite-nanocomposites-as-thermoresponsive-filling-materials-on-dentinal-surface-and-tubules
#12
Paolo Tempesti, Giovanni Simone Nicotera, Massimo Bonini, Emiliano Fratini, Piero Baglioni
HYPOTHESIS: Dental decay, asa consequence of exposure to acidic foods and drinks, represents one of the most important tooth pathologies. Recently, enamel and dentinal surface remineralization using hydroxyapatite nano- and microparticles has been proposed; however, commercial remineralizing toothpastes are quite expensive, mostly due to the high costs of hydroxyapatite. Hence, we propose a thermoresponsive hybrid nanocomposite material as filler for tooth defects. The use of thermoresponsive composite particles aims at filling exposed dentinal tubules in response to a change of temperature in the oral cavity...
September 9, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28894733/the-impact-of-maternal-self-efficacy-and-oral-health-beliefs-on-early-childhood-caries-in-latino-children
#13
Anne R Wilson, Matthew J Mulvahill, Tamanna Tiwari
OBJECTIVES: Latino children experience one of the highest rates of early childhood caries requiring interventions based on valid conceptual frameworks. The Health Belief Model has relevance as a predictor of compliance with health recommendations based on perceptions of a health condition and behaviors to avoid the condition. The model encompasses four perceptual constructs (susceptibility, severity, benefits, barriers) and, for complex conditions, includes self-efficacy as an extended model...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28887419/oxidative-stressors-modify-the-response-of-streptococcus-mutans-to-its-competence-signal-peptides
#14
Matthew De Furio, Sang Joon Ahn, Robert A Burne, Stephen J Hagen
The dental caries pathogen Streptococcus mutans is continually exposed to several types of stress in the oral biofilm environment. Oxidative stress generated by reactive oxygen species has a major impact on the establishment, persistence and virulence of S. mutans. Here, we combined fluorescent reporter-promoter fusions with single-cell imaging to study the effects of reactive oxygen species on activation of genetic competence in S. mutans Exposure to paraquat, which generates superoxide anion, produced a qualitatively different effect on activation of expression of the gene for the master competence regulator, ComX, than did treatment with hydrogen peroxide (H2O2), which can yield hydroxyl radical...
September 8, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28887211/gold-nanoparticles-in-injectable-calcium-phosphate-cement-enhance-osteogenic-differentiation-of-human-dental-pulp-stem-cells
#15
Yang Xia, Huimin Chen, Feimin Zhang, Chongyun Bao, Michael D Weir, Mark A Reynolds, Junqing Ma, Ning Gu, Hockin H K Xu
In this study, a novel calcium phosphate cement containing gold nanoparticles (GNP-CPC) was developed. Its osteogenic induction ability on human dental pulp stem cells (hDPSCs) was investigated for the first time. The incorporation of GNPs improved hDPSCs behavior on CPC, including better cell adhesion (about 2-fold increase in cell spreading) and proliferation, and enhanced osteogenic differentiation (about 2-3-fold increase at 14days). GNPs endow CPC with micro-nano-structure, thus improving surface properties for cell adhesion and subsequent behaviors...
September 5, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28886762/the-tooth-its-structure-and-properties
#16
REVIEW
Dwayne D Arola, Shanshan Gao, Hai Zhang, Radi Masri
This article provides a brief review of recent investigations concerning the structure and properties of the tooth. The last decade has brought a greater emphasis on the durability of the tooth, an improved understanding of the fatigue and fracture behavior of the principal tissues, and their importance to tooth failures. The primary contributions to tooth durability are discussed, including the process of placing a restoration, the impact of aging, and challenges posed by the oral environment. The significance of these findings to the dental community and their importance to the pursuit of lifelong oral health are highlighted...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886707/health-outcomes-of-non-nutritive-sweeteners-analysis-of-the-research-landscape
#17
REVIEW
Szimonetta Lohner, Ingrid Toews, Joerg J Meerpohl
BACKGROUND: Food products containing non-nutritive sweeteners (NNSs) instead of sugar have become increasingly popular in the last decades. Their appeal is obviously related to their calorie-free sweet taste. However, with the dramatic increase in their consumption, it is reasonable and timely to evaluate their potential health benefits and, more importantly, potential adverse effects. The main aim of this scoping review was to map the evidence about health outcomes possibly associated with regular NNS consumption by examining the extent, range, and nature of research activity in this area...
September 8, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28885666/double-acid-etching-treatment-of-dental-implants-for-enhanced-biological-properties
#18
Lluís Giner, Montse Mercadé, Sergi Torrent, Miquel Punset, Román A Pérez, Luis M Delgado, Francisco Javier Gil
BACKGROUND: The topographical features on the surface of dental implants have been considered as a critical parameter for enhancing the osseointegration of implants. In this work, we proposed a surface obtained by a combination of shot blasting and double acid etching. The double acid etching was hypothesized to increase the submicron topography and hence further stimulate the biological properties of the titanium implant. METHODS: The topographical features (surface roughness and real surface area), wettability and surface chemical composition were analyzed...
September 8, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28883989/osteoinductive-effects-of-preoperative-dexamethasone-in-human-dental-pulp-stem-cells-primary-culture
#19
Rani da Cunha Moretti, Monica Talarico Duailibi, Paulo Oliveira Martins, Jennifer Adriane Dos Santos, Silvio Eduardo Duailibi
AIM: The use of dexamethasone (DEX) in mesenchymal cell culture induces osteoblastic differentiation and, consequently, formation of mineralized tissues. Tissue engineering proposes the development of therapeutic strategies aimed at structural and functional regeneration of biological tissues. In this sense, cell characterization in vitro is critical to ensure the development of such techniques. Our objective was to evaluate the osteoinductive effect of DEX administered as a preoperative medication in primary cell culture of human dental pulp stem cell...
August 2017: Future Science OA
https://www.readbyqxmd.com/read/28879345/managing-the-behavior-of-a-patient-with-autism-by-sedation-via-submucosal-route-during-dental-treatment
#20
Chan-Woo Jo, Chan-Hee Park, Jong-Hyug Lee, Ji-Hun Kim
In sedation via the submucosal route, the drug is administered through the maxillary buccal submucosa. It is time saving, effective, and safe. Patients with autism, a mental disorder, often find it hard to make relationships with other people. These patients display a strong resistance to dental treatment and sedation. This study reports a successful case of behavioral management during dental treatment, using sedation via the submucosal route. The patient was strongly resistant to sedation via the oral, intramuscular, and intravenous routes...
June 2017: J Dent Anesth Pain Med
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