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Thailand Metabolic Syndrome

Sanguansak Rerksuppaphol, Lakkana Rerksuppaphol
BACKGROUND: Obesity is considered to be a risk of metabolic syndrome; however, data on the prevalence of metabolic syndrome in Thai obese children are scarce. OBJECTIVE: The present study aims to determine the prevalence of metabolic syndrome in Thai obese children. MATERIAL AND METHOD: A cross-sectional study was conducted on 113 obese children who were students of a public elementary school in Ongkharak district, Thailand, in 2013. Anthropometric data, blood pressure and biochemical parameters were measured...
November 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Nakarin Sansanayudh, Dittapol Muntham, Sukit Yamwong, Piyamitr Sritara, Tawatchai Akrawichien, Ammarin Thakkinstian
BACKGROUND: Mean platelet volume (MPV) correlates with platelet activation and has recently emerged as a potential marker of cardiovascular diseases. Previous publications also suggest possible association between MPV and some cardiovascular risk factors but the evidences are still conflicting and inconclusive. OBJECTIVE: To study the association between MPV and cardiovascular risk factors. METHODS: This is a cross-sectional study using data from the second survey of the Electricity Generating Authority of Thailand (EGAT) cohort...
May 2016: European Journal of Internal Medicine
Taned Chitapanarux, Kannika Phornphutkul
Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. The incidence of HCC is on the rise in Thailand, where it has become the most common malignancy in males and the third most common in females. Here, we review some of the risk factors that have contributed to this increase in HCC incidence in the Thai population. Hepatitis B virus (HBV) is the main etiologic risk factor for HCC, followed by hepatitis C virus (HCV). Patients with HBV genotype C have a higher positive rate of hepatitis B early antigen (HBeAg) and progress to cirrhosis and HCC earlier than genotype B...
September 28, 2015: Journal of Clinical and Translational Hepatology
Kazuya Toda, Shogo Takeda, Shoketsu Hitoe, Seikou Nakamura, Hisashi Matsuda, Hiroshi Shimoda
Enhancement of muscular energy production is thought to improve locomotive functions and prevent metabolic syndromes including diabetes and lipidemia. Black ginger (Kaempferia parviflora) has been cultivated for traditional medicine in Thailand. Recent studies have shown that black ginger extract (KPE) activated brown adipocytes and lipolysis in white adipose tissue, which may cure obesity-related dysfunction of lipid metabolism. However, the effect of KPE on glucose and lipid utilization in muscle cells has not been examined yet...
April 2016: Journal of Natural Medicines
Nutjaree Jeenduang, Sureerut Porntadavity, Manit Nuinoon, Dararat Horpet, Nongyao Thepkwan, Pattamawadee Thaworn, Suporn Theanmontri
Several genetic factors have been investigated responsible for metabolic syndrome (MetS). The aim of this study was to investigate the association between cholesteryl ester transfer protein (CETP) TaqIB and apolipoprotein E (ApoE) polymorphisms and MetS in 378 subjects from Southern Thailand. Subjects were divided into MetS+ (n = 121) and MetS- (n = 257) groups according to the criteria of National Cholesterol Education Program Adult Treatment Panel III (NCEP ATPIII). The CETP TaqIB and ApoE polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique...
August 2015: Biochemical Genetics
Lakkana Rerksuppaphol, Sanguansak Rerksuppaphol
BACKGROUND: Metabolic syndrome in children has become the focus of many research projects in recent years. The main goal of this study is to evaluate the prevalence of metabolic syndrome in Thai children and its correlation with overweight and obesity. MATERIAL AND METHODS: A cross-sectional study of 348 children enrolled in grade 1 to grade 9 was done in Ongkhaluck province in Thailand. Demographic and anthropometric data were gathered. Blood tests were also performed to check for blood glucose, total cholesterol, and triglycerides...
April 2014: Journal of Clinical and Diagnostic Research: JCDR
Jureeporn Jantarapakde, Nittaya Phanuphak, Chintana Chaturawit, Supabhorn Pengnonyang, Pornpen Mathajittiphan, Piyaporn Takamtha, Narunat Dungjun, Suteeraporn Pinyakorn, Warabhorn Pima, Wisit Prasithsirikul, Praphan Phanuphak
Metabolic syndrome (MS), a group of interrelated risk factors for cardiovascular diseases (CVD) and type 2 diabetes, has been increasingly reported among HIV-infected patients. Data on the prevalence and risk factors for MS among HIV-1 infected Thai adults are limited. The study collected cross-sectional data from 580 HIV-1 infected adults-46.2% were men and 71% were antiretroviral therapy (ART)-experienced. The majority (78.8%) of them used non-nucleoside reverse transcriptase inhibitor-based regimens. Data on lipid profiles, fasting blood glucose, CD4 count, HIV RNA, antiretroviral therapy (ART), anthropometry, food intake, and exercise were recorded...
July 2014: AIDS Patient Care and STDs
Nakarin Sansanayudh, Supakit Wongwiwatthananukit, Nongluk Phetkrajaysang, Sarinee Krittiyanunt
BACKGROUND: Vitamin D deficiency is a common problem worldwide. Several studies have shown an association between vitamin D deficiency and the increased risk of metabolic syndrome. No previous study has compared the efficacy and safety of ergocalciferol at 40,000 versus 20,000 IU/week in patients with metabolic syndrome. OBJECTIVE: To evaluate the efficacy of ergocalciferol supplementation on serum 25-hydroxyvitamin D [25(OH)D] concentrations and to examine safety parameters in metabolic syndrome patients...
August 2014: International Journal of Clinical Pharmacy
Manirat Therawiwat, Nirat Imamee, Thaweesak Khamklueng
OBJECTIVE: To determine factors related to stages of change regarding dietary intake of persons with metabolic syndrome in Uthai Thani. MATERIAL AND METHOD: Five hundred metabolic syndrome persons were randomly selected using a three-stage sampling method and voluntarily responded to a validated, self-administered questionnaire. RESULTS: Majority of the respondents (36.4%) had dietary practices in the pre-contemplation stage while only 17...
December 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Jongkol Podang, Piyamitr Sritara, Kulaya Narksawat
OBJECTIVE: To determine prevalence and factors associated with metabolic syndrome (MetS) among employees of the Electricity Generating Authority of Thailand based in Bangkok. MATERIAL AND METHOD: The present study was conducted among 2,544 participants (1,875 men, 669 women) enrolled in the cohort study of Faculty of Medicine, Ramathibodi Hospital. Baseline cross sectional data in 2009 was analyzed. The MetS was defined using NCEP ATP III criteria. Odds ratios (OR) and 95% confidence interval (95% CI) stratified by gender were computed...
December 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Kulaya Narksawat, Dusit Sujirarat, Panuwat Panket
OBJECTIVE: To determine associations of individual and combined effects of hypertension and diabetes with stroke among Thais aged 55 years and older MATERIAL AND METHOD: Cross-sectional data from national screening program for metabolic syndrome in Thailand for the year 2010 among participants who lived in central region of Thailand were used. The number of participants was 13,268 in the analysis. RESULTS: The prevalence of stroke was 0.9%...
December 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Nijasri C Suwanwela
Stroke is a major health burden in Thailand. It is the leading cause of death and long term disability in both men and women. Despite the improvement of healthcare system, the mortality rate of stroke is still increasing during the past 5 years. The incidence of stroke in Thailand is now being studied in a large population based cohort. The prevalence of stroke is estimated to be 1.88% among adults 45 years and older. Stroke is more prevalent in men than in women and the mean age of stroke onset is 65 years...
January 2014: Journal of Stroke
Nutjaree Jeenduang, Rangsiri Trongsakul, Pariwat Inhongsa, Preeyaporn Chaidach
OBJECTIVE: To assess the prevalence of metabolic syndrome (MetS) in premenopausal and postmenopausal women in Southern Thailand. METHODS: A cross-sectional study was conducted with 361 healthy women (218 premenopausal women and 143 postmenopausal women) in Southern Thailand. Blood pressure, anthropometric indices, fasting plasma glucose and serum lipid levels were measured. MetS was defined according to criteria of the "National Cholesterol Education Program Adult Panel Treatment III" (NCEP ATPIII)...
August 2014: Gynecological Endocrinology
Supornpim Chearskul, Mayuree Homsanit, Supornpim Chearskul, Mayuree Homsanit, Kamol Udol, Suwattanee Kooptiwut, Malika Churintaraphan, Namoiy Semprasert, Smarn Onreabroi
BACKGROUND: The prevalence of metabolic syndrome (MS) accompanied with cardiometabolic complications has progressively increased in Thailand. The roles of insulin resistance, leptin, adiponectin, and free testosterone as prognostic indicators of MS among Thai population were evaluated MATERIAL AND METHOD: Men and women aged 34 to 89 years (n = 308) having 0-5 criteria of MS according to NCEP III with Asian-specific cut-points for waist circumference were enrolled in this cross-sectional study...
January 2014: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
P Ruangkanchanasetr, Bancha Satirapoj, S Bunnag, A Vongwiwatana, N Premasathian, Y Avihingsanon
BACKGROUND: Obesity is a risk factor for cardiovascular disease and cardiovascular mortality in renal transplant recipients (RTRs). There are limited studies of prevalence and associated factors of obesity in Asian RTRs. METHODS: A cross-sectional study was conducted from July to December 2012 in 4 kidney transplant centers in Bangkok, Thailand. Obesity was diagnosed based on the International Obesity Taskforce-proposed classification. At risk of obesity, obese I, and obese II were defined as having a body mass index (BMI) of 23-24...
2014: Transplantation Proceedings
Kanjana Suriyaprom, Benjaluck Phonrat, Rungsunn Tungtrongchitr
The metabolic syndrome is related to increased risk of developing cardiovascular disease and type 2 diabetes. Adiponectin is an adipocyte-secreted protein with insulin-sensitizing and anti-atherogenic properties. The aims of this study were to evaluate adiponectin levels and biochemical parameters in metabolic-syndrome subjects and healthy controls. The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome...
2014: Asia Pacific Journal of Clinical Nutrition
Sirianong Namwongprom, Kittipan Rerkasem, Antika Wongthanee, Sakda Pruenglampoo, Ampica Mangklabruks
OBJECTIVE: The aim of this study was to compare body fat distribution using dual-energy X-ray absorptiometry (DXA) in young adult subjects with metabolic syndrome (MS) with those without MS and also to determine whether a significant association existed between total body fat mass (FM) and MS along with the effect of birth weight. METHODS: This cross-sectional study was conducted on 393 young adult subjects (175 male, 218 female). Body mass index (BMI), waist circumference, blood pressure, triglyceride, high-density lipoprotein cholesterol and glucose levels were determined...
2013: Journal of Clinical Research in Pediatric Endocrinology
Jamabhorn Jaipakdee, Wiroj Jiamjarasrangsri, Vitool Lohsoonthorn, Somrat Lertmaharit
Metabolic syndrome (MetS) and hyperuricemia are important risk factors for cardiovascular disease, hypertension and renal disease. The relationship between serum uric acid (UA) levels and MetS remains unclear. In the present study we determined the presence of MetS and measured UA levels among personnel at the Thai Red Cross Society and Chulalongkorn University to evaluate the possible presence of an association between the two. We conducted this cross sectional study in 2009. A total of 2,804 persons, aged 35-60 years (628 men and 2176 women) filled out questionnaires, had laboratory testing and were included in the study...
May 2013: Southeast Asian Journal of Tropical Medicine and Public Health
Nopparat Pengsalae, Chuchai Tanglertsampan, Thanapat Phichawong, Saridpong Lee
BACKGROUND: There are many studies of the association between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MS), which is known to increase the risk of cardiovascular diseases. However the results are inconsistent. There is no study in a Thai population. OBJECTIVE: To evaluate the association of early-onset AGA and metabolic syndrome in Thai male patients. MATERIAL AND METHOD: Patients were recruited from the check-up clinic...
August 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Ammarin Thakkinstian, Laor Chailurkit, Daruneewan Warodomwichit, Wipa Ratanachaiwong, Sukit Yamwong, Suwannee Chanprasertyothin, John Attia, Piyamitr Sritara, Boonsong Ongphiphadhanakul
OBJECTIVE: Fetuin-A is associated with body mass index (BMI) as well as components of the metabolic syndrome. However, it is unclear if fetuin-A affects BMI or the other way around. We therefore assessed the causal association between fetuin-A and BMI or vice versa, utilizing a bidirectional Mendelian randomization approach. DESIGN AND METHODS: This was a study of 2558 subjects from the Electricity Generating Authority of Thailand (EGAT) cohort. Two polymorphisms, that is, rs2248690 in the alpha2-Hereman-Schmid glycoprotein (AHSG) gene and rs9939609 in the fat mass and obesity-associated (FTO) gene were genotyped...
August 2014: Clinical Endocrinology
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