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relation vitamin d and obesity

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https://www.readbyqxmd.com/read/27876009/lifestyle-medication-and-socio-demographic-determinants-of-mental-and-physical-health-related-quality-of-life-in-people-with-multiple-sclerosis
#1
George A Jelinek, Alysha M De Livera, Claudia H Marck, Chelsea R Brown, Sandra L Neate, Keryn L Taylor, Tracey J Weiland
BACKGROUND: Health-related quality of life (QOL) is a key outcome for people with multiple sclerosis (MS). While modifiable lifestyle factors, like smoking, physical activity and vitamin D, have strong associations with development and progression of MS, few studies have examined such associations with QOL. METHODS: Using patient-reported data from 2312 people with MS from 54 countries, regression models explored associations of socio-demographic, therapeutic and lifestyle factors with QOL, using the Multiple Sclerosis Quality of Life-54 (MSQOL-54)...
November 22, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27864670/relationship-between-vitamin-d-deficiency-and-the-components-of-metabolic-syndrome-in-patients-with-morbid-obesity-before-and-1%C3%A2-year-after-laparoscopic-roux-en-y-gastric-bypass-or-sleeve-gastrectomy
#2
Ana Obispo Entrenas, David Legupin Tubio, Fabiola Lucena Navarro, Francisco Martin Carvajal, Norberto Gandara Adan, Maximino Redondo Bautista, Jimena Abiles Osinaga
BACKGROUND: Vitamin D deficiency (VDD) is associated with obesity and metabolic syndrome (MS). After bariatric surgery (BS), high rates of VDD often persist and some patients are refractory to the resolution of comorbidities. The aim of the present study is to analyse the relationship between the levels of vitamin D and the persistence of MS components at 12 months after BS, according to the surgical technique used. METHODS: We performed a retrospective study of 46 patients undergoing BS: 23 underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP) and 23 laparoscopic sleeve gastrectomy (LSG)...
November 18, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27860112/race-or-vitamin-d-a-determinant-of-intima-media-thickness-in-obese-adolescents
#3
Fida Bacha, Silva A Arslanian
OBJECTIVE: Carotid intima media thickness (IMT), a predictor of cardiovascular events, is reported to be higher in African-American (AA) vs White (AW) individuals. We investigated whether racial differences in IMT in obese adolescents could be explained by differences in 25 hydroxy-vitamin D [25(OH)D]. RESEARCH DESIGN AND METHODS: A total of 63 obese adolescents had 25(OH)D levels, determination of IMT, body composition, insulin sensitivity (IS) by hyperinsulinemic-euglycemic clamp, lipids and blood pressure (BP)...
November 17, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27852618/relation-between-milk-fat-percentage-vitamin-d-and-bmi-z-score-in-early-childhood
#4
Shelley M Vanderhout, Catherine S Birken, Patricia C Parkin, Gerald Lebovic, Yang Chen, Deborah L O'Connor, Jonathon L Maguire
BACKGROUND: Fortified cow milk is a material contributor of vitamin D and dietary fat in children. Recommendations for children >2 y of age advise reduced milk-fat consumption to reduce childhood obesity, yet the relation between lower milk fat, vitamin D stores, and body mass index (BMI) is unclear. OBJECTIVES: The primary objective was to explore the association between milk-fat percentage and both BMI z score (zBMI) and venous 25-hydroxyvitamin D [25(OH)D]; the secondary objective was to assess whether milk volume consumed modified this relation...
November 16, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27837387/vitamin-d3-loading-is-superior-to-conventional-supplementation-after-weight-loss-surgery-in-vitamin-d-deficient-morbidly-obese-patients-a-double-blind-randomized-placebo-controlled-trial
#5
Maria Luger, Renate Kruschitz, Christian Kienbacher, Stefan Traussnigg, Felix B Langer, Gerhard Prager, Karin Schindler, Enikö Kallay, Friedrich Hoppichler, Michael Trauner, Michael Krebs, Rodrig Marculescu, Bernhard Ludvik
BACKGROUND: Bariatric patients often suffer from vitamin D deficiency (VDD), and both, morbid obesity and VDD, are related to non-alcoholic fatty liver disease. However, limited data are available regarding best strategies for treating VDD, particularly, in bariatric patients undergoing omega-loop gastric bypass (OLGB). Therefore, we examined the efficacy and safety of a forced vitamin D dosing regimen and intervention effects in liver fibrotic patients. METHODS: In this double-blind, randomized, placebo-controlled trial, 50 vitamin D-deficient patients undergoing OLGB were randomly assigned to receive, in the first month postoperatively, oral vitamin D3 (≤3 doses of 100,000 IU; intervention group) or placebo as loading dose (control group) with subsequent maintenance dose (3420 IU/day) in both groups until 6-month visit...
November 12, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27833859/associations-of-25-hydroxyvitamin-d-with-markers-of-inflammation-insulin-resistance-and-obesity-in-black-and-white-community-dwelling-adults
#6
Jennifer L Jackson, Suzanne E Judd, Bhupesh Panwar, Virginia J Howard, Virginia G Wadley, Nancy S Jenny, Orlando M Gutiérrez
AIMS: Vitamin D is a fat-soluble vitamin classically known for its role in calcium absorption and bone health. Growing evidence indicates that vitamin D deficiency may be associated with inflammation, insulin resistance, and obesity. However, prior studies examining the association of vitamin D with metabolic risk factors had relatively low representation of individuals of black race, limiting their ability to characterize associations of vitamin D and parameters of metabolic health in black vs...
September 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/27827910/the-effect-of-serum-25-hydroxyvitamin-d-concentrations-on-elevated-serum-c-reactive-protein-concentrations-in-normal-weight-overweight-and-obese-participants-of-a-preventive-health-program
#7
Silmara S B S Mastroeni, Lalani L Munasinghe, Truong-Minh Pham, Sarah A Loehr, John Paul Ekwaru, Marco F Mastroeni, Paul J Veugelers
The hypothesized effect of vitamin D on C-reactive protein (CRP) has received substantial attention as a potential means to alleviate the risk for cardiovascular disease. However, observational studies have been inconsistent in their reporting of associations between serum 25-hydroxyvitamin D (25(OH)D) and CRP concentrations, and trials and meta analyses have been inconsistent in their conclusions regarding the effect of vitamin D supplementation on CRP concentrations. These supplementation trials were mostly conducted among patients with more or less inflammatory complications and did not consider potential distinctive effects by weight status...
November 4, 2016: Nutrients
https://www.readbyqxmd.com/read/27776717/metabolically-obese-individuals-of-normal-weight-have-a-high-risk-of-25-hydroxyvitamin-d-deficiency
#8
Xiaoli Wang, Xiangyun Chang, Yurong Zhu, Huan Wang, Kan Sun
BACKGROUND: Vitamin D status is related to obesity-related metabolic disorders. We investigated the risk of 25-hydroxyvitamin D [25(OH)D] deficiency among different metabolic phenotypes. METHODS: This prospective cross-sectional study evaluated 1,292 individuals who were ≥40 years old. Participants were classified as metabolically healthy and normal weight (MHNW), metabolically obese but normal weight (MONW), metabolically healthy but obese (MHO) or metabolically unhealthy and obese (MUO)...
October 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27721113/a-vitamin-d-pathway-gene-gene-interaction-affects-low-density-lipoprotein-cholesterol-levels
#9
Nathália Grave, Luciana Tovo-Rodrigues, Janaína da Silveira, Diego Luiz Rovaris, Simone Morelo Dal Bosco, Verônica Contini, Júlia Pasqualini Genro
Much evidence suggests an association between vitamin D deficiency and chronic diseases such as obesity and dyslipidemia. Although genetic factors play an important role in the etiology of these diseases, only a few studies have investigated the relationship between vitamin D-related genes and anthropometric and lipid profiles. The aim of this study was to investigate the association of three vitamin D-related genes with anthropometric and lipid parameters in 542 adult individuals. We analyzed the rs2228570 polymorphism in the vitamin D receptor gene (VDR), rs2134095 in the retinoid X receptor gamma gene (RXRG) and rs7041 in the vitamin D-binding protein gene (GC)...
August 15, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27720018/pathways-through-which-asthma-risk-factors-contribute-to-asthma-severity-in-inner-city-children
#10
Andrew H Liu, Denise C Babineau, Rebecca Z Krouse, Edward M Zoratti, Jacqueline A Pongracic, George T O'Connor, Robert A Wood, Gurjit K Khurana Hershey, Carolyn M Kercsmar, Rebecca S Gruchalla, Meyer Kattan, Stephen J Teach, Melanie Makhija, Dinesh Pillai, Carin I Lamm, James E Gern, Steven M Sigelman, Peter J Gergen, Alkis Togias, Cynthia M Visness, William W Busse
BACKGROUND: Pathway analyses can be used to determine how host and environmental factors contribute to asthma severity. OBJECTIVE: To investigate pathways explaining asthma severity in inner-city children. METHODS: On the basis of medical evidence in the published literature, we developed a conceptual model to describe how 8 risk-factor domains (allergen sensitization, allergic inflammation, pulmonary physiology, stress, obesity, vitamin D, environmental tobacco smoke [ETS] exposure, and rhinitis severity) are linked to asthma severity...
October 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27717662/the-most-effective-factors-to-offset-sarcopenia-and-obesity-in-the-older-korean-physical-activity-vitamin-d-and-protein-intake
#11
Chorong Oh, Byeong Hwan Jeon, Shaun Nicholas Reid Storm, Sunkug Jho, Jae-Kyung No
OBJECTIVE: The aim of this study was to evaluate the effects of the types and levels of physical activity in conjunction with protein intake and vitamin D on sarcopenia and obesity status in an elderly population. METHODS: Study participants (N = 4452) were ages ≥60 y and included 1929 men and 2523 women who completed a body composition analysis with a dual energy x-ray absorptiometry and provided health and dietary data. RESULTS: Higher appendicular skeletal muscle mass/weight was observed in the non-obese group, although obese participants had greater weights...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27716304/appropriate-vitamin-d-loading-regimen-for-patients-with-advanced-lung-cancer
#12
L John Hoffer, Line Robitaille, Nelda Swinton, Jason Agulnik, Victor Cohen, David Small, Carmela Pepe, Shaun Eintracht
BACKGROUND: Most patients attending cancer clinics have hypovitaminosis D. Correcting or preventing this abnormal condition could mitigate the emotional and physical complications of their disease, but clinical trials of vitamin D therapy in this setting are hindered by the unavailability of safe, effective and practical loading dose regimens. METHODS: In this single arm open-label pharmacokinetic trial, outpatients with advanced lung cancer consumed 20,000 IU vitamin D daily with the largest meal of the day for 14 days followed by 10,000 IU per day for a further 7 days...
October 6, 2016: Nutrition Journal
https://www.readbyqxmd.com/read/27710010/predicting-severe-asthma-exacerbations-in-children
#13
Sandeep Puranik, Erick Forno, Andrew Bush, Juan C Celedón
Severe exacerbations negatively impact the quality of life and education of children with asthma, while also causing substantial healthcare costs. Preventing severe asthma exacerbations requires identifying patients at high risk, in order to develop personalized care protocols to prevent such exacerbations. In this review, we assess and discuss recently published data on risk factors and predictive tools for severe asthma exacerbations in childhood. Although few genome-wide association studies have focused on severe asthma exacerbations, one such study recently identified cadherin-related family member 3 (CDHR3, implicated on integrity of the airway epithelium), as a susceptibility gene for recurrent severe asthma exacerbations in young children...
October 6, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27703587/an-updated-mini-review-of-vitamin-d-and-obesity-adipogenesis-and-inflammation-state
#14
Zujaja-Tul-Noor Hamid Mehmood, Dimitrios Papandreou
Vitamin D related research continues to expand and theorise regarding its involvement in obesity, as both hypovitaminosis D and obesity strike in pandemic proportions. Vitamin D plays an important role in immune system through Vitamin D Receptors (VDR), which are transcription factors located abundantly in the body. Due to this characteristic, it is potentially linked to obesity, which is a state of inflammation involving the release of cytokines from adipose tissue, and exerting stress on other organs in a state of positive energy balance...
September 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27698344/maternal-vitamin-d-beneficially-programs-metabolic-gut-and-bone-health-of-mouse-male-offspring-in-an-obesogenic-environment
#15
C R Villa, J Chen, B Wen, S M Sacco, A Taibi, W E Ward, E M Comelli
BACKGROUND/OBJECTIVES: Vitamin D is an anti-inflammatory nutrient and a determinant of bone health. Some prospective studies suggest that maternal vitamin D status is positively associated with offspring bone mass. We found that serum concentrations of lipopolysaccharide (LPS), an inflammatory molecule related to adiposity, insulin resistance and bone resorption, is lower in healthy mouse offspring exposed to high dietary vitamin D during pregnancy and lactation. LPS reaches the circulation via the gut...
October 25, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27693095/clinical-practice-guidelines-for-vitamin-d-in-the-united-arab-emirates
#16
Afrozul Haq, Sunil J Wimalawansa, Pawel Pludowski, Fatme Al Anouti
In the UAE and the Gulf region in general, there are several intricate public health issues in the context of vitamin D deficiency that needs to be addressed. Changes in lifestyle such as diet, lack of exercise, cultural habits, avoiding sun exposure due to excessive heat, and other risk factors predispose those who live in GULF countries, such as Emiratis likely to becoming vitamin D deficient. Consequently, the prevalence of vitamin D deficiency is high, and new guidelines are needed to overcome this major public health issue...
September 28, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27692990/body-adiposity-predictors-of-vitamin-d-status-in-nondialyzed-patients-with-chronic-kidney-disease-a-cross-sectional-analysis-in-a-tropical-climate-city
#17
Maria Inês Barreto Silva, Vanessa Vicente de Souza Cavalieri, Carla Cavalheiro da Silva Lemos, Márcia Regina Simas Torres Klein, Rachel Bregman
OBJECTIVES: The association of vitamin D status with high body adiposity is poorly investigated in the chronic kidney disease (CKD) population. The aim of the present study was to describe vitamin D status and to identify body adiposity predictors of vitamin D deficiency, in a nondialyzed CKD population inhabiting a tropical city. METHODS: This cross-sectional study included patients with CKD, defined as estimated glomerular filtration rate (eGFR) <60 mL/min, regularly treated by an interdisciplinary team in an outpatient university clinic, set in a Brazilian city (latitude: 22°54'S; 43°12'W)...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27687738/serum-25-hydroxyvitamin-d-concentration-is-not-associated-with-glomerular-filtration-rate-in-a-predominantly-obese-otherwise-healthy-population
#18
Negar Naderpoor, Aya Mousa, Maximilian P J de Courten, Robert Scragg, Sanjeeva Ranasinha, Barbora de Courten
Evidence from observational studies indicates a role for vitamin D in kidney function and progression to chronic kidney disease. Findings from animal studies have proposed underlying mechanisms including increased activation of the renin-angiotensin system, increased blood pressure, insulin resistance and chronic low-grade inflammation. However, human studies are limited by confounders arising from heterogeneous samples of participants. We examined the relationship between 25(OH)D and estimated glomerular filtration rate (eGFR) in a predominantly obese otherwise healthy and drug-naive population with no history of chronic kidney disease (CKD)...
September 28, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27685818/the-association-between-25-hydroxyvitamin-d-and-airway-obstruction-in-asthma
#19
K Hutchinson, C Kerley, L Cormican, Y Rochev, J Faul
Since Vitamin D has anti-inflammatory effects we wondered whether the association between low serum 25OHD and airway obstruction in moderate persistent asthma might be explained by inflammatory pathways that worsen asthma. All subjects examined were Irish Caucasians with moderate persistent asthma and none took systemic steroid therapy. In addition to computerized spirometry, we measured BMI, serum 25-hydroxyvitamin D (25OHD), total IgE, Eosinophil Cationic Protein (ECP), and high sensitive C- reactive protein (hs-CRP)...
March 10, 2016: Irish Medical Journal
https://www.readbyqxmd.com/read/27684845/the-prevalence-and-factors-associate-with-vocal-nodules-in-general-population-cross-sectional-epidemiological-study
#20
Seong Jun Won, Rock Bum Kim, Jin Pyeong Kim, Jung Je Park, Min Su Kwon, Seung Hoon Woo
The purpose of this study was to analyze the prevalence of vocal nodules and to identify factors related with an increased risk for vocal nodules.This study was conducted using data from the Korean National Health and Nutrition Examination Survey 2008 to 2011. The subjects consisted of 19,636 men and women aged ≥19 years. Related factors such as age, marital status, incomes, and education level were assessed in individual interviews, and health-related behaviors including smoking, alcohol, and activity were assessed with self-administered questionnaires...
September 2016: Medicine (Baltimore)
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