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relation vitamin d and obesity

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https://www.readbyqxmd.com/read/29892562/impact-of-vitamin-d-treatment-on-25-hydroxy-vitamin-d-levels-and-insulin-homeostasis-in-obese-african-american-adolescents-in-a-randomized-trial
#1
Usha Sethuraman, Marwan A Zidan, Lynae Hanks, Minoo Bagheri, Ambika Ashraf
Background: Obesity is affecting children in epidemic proportions in the United States with nearly 25% of children being obese. Consequences of obesity including dyslipidemia, type 2 diabetes and cardiovascular disease are leading to morbidity at younger ages. Parallel to the obesity and diabetes epidemics, the prevalence of vitamin D deficiency has reached very high levels and has been associated with insulin resistance and dyslipidemia. Studies exploring the impact of vitamin D repletion on insulin sensitivity and dyslipidemia in children are sparse...
June 2018: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29892041/effectiveness-of-vitamin-d-therapy-in-improving-metabolomic-biomarkers-in-obesity-phenotypes-two-randomized-clinical-trials
#2
Farshad Farzadfar, Abolghasem Djazayery, Lu Qi, Minoo Bagheri, Mir Saeed Yekaninejad, Maryam Chamari, Maryam Naderi, Zarin Ebrahimi, Berthold Koletzko, Olaf Uhl
BACKGROUND: Uncertainty remains about the effect of vitamin D therapy on biomarkers of health status in obesity. The molecular basis underlying this controversy is largely unknown. OBJECTIVE: To address the existing gap, our study sought to compare changes in metabolomic profiles of obesity phenotypes (metabolically healthy obese (MHO) and metabolically unhealthy obese (MUHO)) patients with sub-optimal levels of vitamin D following vitamin D supplementation. METHODS: We conducted two randomized double-blind clinical trials on participants with either of the two obesity phenotypes from Tehran province...
June 11, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29875026/adequacy-of-nutritional-intake-during-pregnancy-in-relation-to-prepregnancy-bmi-results-from-the-3d-cohort-study
#3
Lise Dubois, Maikol Diasparra, Brigitte Bédard, Cynthia K Colapinto, Bénédicte Fontaine-Bisson, Richard E Tremblay, William D Fraser
Our study compares adequacy of nutritional intakes among pregnant women with different prepregnancy BMI and explores associations between nutritional intakes during pregnancy and both prepregnancy BMI and gestational weight gain (GWG). We collected dietary information from a large cohort of pregnant Canadian women (n 861) using a 3-d food record. We estimated usual dietary intakes of energy (E), macronutrients and micronutrients using the National Cancer Institute method. We also performed Pearson's correlations between nutritional intakes and both prepregnancy BMI and GWG...
June 7, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29862141/the-role-of-diet-and-lifestyle-in-women-with-breast-cancer-an-update-review-of-related-research-in-the-middle-east
#4
REVIEW
Zainab Taha, Sakina E Eltom
Breast cancer is the most common malignancy among Arab women in Eastern Mediterranean Region (EMR). The incidence of breast cancer has substantially increased in recent years among this women population, especially those younger than 50, and the incidence is expected to double by 2030. Considerable experimental evidence supports the potential role of dietary habits and lifestyle in cancer etiology and cancer prevention. In this review we examined the literature for evidence to link dietary choices and the rise in incidence and mortality of breast cancer among women in EMR...
2018: BioResearch Open Access
https://www.readbyqxmd.com/read/29795471/early-weight-loss-outcomes-from-a-newly-established-hospital-affiliated-specialized-obesity-care-delivery-model-in-central-florida
#5
Gitanjali Srivastava, Cynthia Buffington
SIGNIFICANCE: We evaluated weight loss outcomes in a newly established hospital-affiliated, physician-directed multidisciplinary, and personalized obesity care model. METHODS: Fifty established patients in a specialized obesity medicine practice underwent intensive lifestyle intervention ±adjunctive pharmacotherapy (46/50) for >6 consecutive months and when required, psychological intervention. We identified demographics, obesity-related comorbidities, anthropometric changes over time, and laboratory screen...
May 24, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29755414/non-synonymous-single-nucleotide-polymorphisms-and-physical-activity-interactions-on-adiposity-parameters-in-malaysian-adolescents
#6
Nur Lisa Zaharan, Nor Hanisah Muhamad, Muhammad Yazid Jalaludin, Tin Tin Su, Zahurin Mohamed, M N A Mohamed, Hazreen A Majid
Background: Several non-synonymous single-nucleotide polymorphisms (nsSNPs) have been shown to be associated with obesity. Little is known about their associations and interactions with physical activity (PA) in relation to adiposity parameters among adolescents in Malaysia. Methods: We examined whether (a) PA and (b) selected nsSNPs are associated with adiposity parameters and whether PA interacts with these nsSNPs on these outcomes in adolescents from the Malaysian Health and Adolescents Longitudinal Research Team study ( n  = 1,151)...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29754264/one-year-impact-of-bariatric-surgery-on-serum-anti-mullerian-hormone-levels-in-severely-obese-women
#7
Clara Vincentelli, Marie Maraninchi, René Valéro, Sophie Béliard, Flavia Maurice, Olivier Emungania, Bruno Berthet, Elise Lombard, Anne Dutour, Bénédicte Gaborit, Blandine Courbiere
INTRODUCTION: Although bariatric surgery seems to increase spontaneous fertility by improving ovulatory function in young women, its impact on ovarian reserve remains largely unknown. OBJECTIVE: To evaluate changes in serum anti-Mullerian hormone (AMH) levels in reproductive-age severely obese women after bariatric surgery (BS). METHODS: AMH levels were measured retrospectively in 39 women (mean age 34.6 ± 1.1 years, range 18-45) that underwent a sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) at baseline, and 6 and 12 months after BS...
May 12, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29745981/evaluation-of-biochemical-endocrine-and-metabolic-biomarkers-for-the-early-diagnosis-of-polycystic-ovary-syndrome-among-non-obese-saudi-women
#8
Maha H Daghestani
OBJECTIVE: To investigate the potential of selected biochemical, endocrine, and metabolic biomarkers for early diagnosis of polycystic ovary syndrome (PCOS) among non-obese women. METHODS: A prospective observational cross-sectional study was conducted at three medical centers in Makkah, Saudi Arabia, between July 15 and September 20, 2017. Eligible participants were non-obese women diagnosed with PCOS according to the Rotterdam criteria (n=44) and non-obese normo-ovulatory women without signs of PCOS (control group; n=44)...
May 10, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29738471/the-association-between-sleep-duration-and-25-hydroxyvitamin-d-concentration-with-obesity-in-an-elderly-korean-population-a-cross-sectional-study
#9
Miae Doo
Studies have recently reported an association between sleep duration and obesity in some individuals. Vitamin D deficiency is common in elderly populations and is also associated with obesity. In this study, the combined interaction effect of vitamin D levels and sleep duration on obesity-related variables was analyzed in 3757 individuals from an elderly Korean population using the Korean National Health and Nutrition Examination Survey. Significant differences were observed in the interaction effect of the vitamin D levels and sleep duration on obesity-related variables, including BMI ( p = 0...
May 8, 2018: Nutrients
https://www.readbyqxmd.com/read/29735578/lifestyle-and-environmental-factors-in-multiple-sclerosis
#10
Lars Alfredsson, Tomas Olsson
Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS), because genetic predisposition only explains a fraction of the risk increase. There is strong evidence for associations of Epstein-Barr virus (EBV) infection, smoking, sun exposure/vitamin D, and adolescent obesity to risk of MS. There is also circumstantial evidence on organic solvents and shift work, all associate with greater risk, although certain factors like nicotine, alcohol, and a high coffee consumption associate with a reduced risk...
May 7, 2018: Cold Spring Harbor Perspectives in Medicine
https://www.readbyqxmd.com/read/29725975/probiotic-supplementation-in-morbid-obese-patients-undergoing-one-anastomosis-gastric-bypass-mini-gastric-bypass-oagb-mgb-surgery-a-randomized-double-blind-placebo-controlled-clinical-trial
#11
Zohreh Karbaschian, Zeinab Mokhtari, Abdolreza Pazouki, Ali Kabir, Mahdi Hedayati, Somayeh Soleymanzadeh Moghadam, Parvin Mirmiran, Azita Hekmatdoost
BACKGROUND: Bariatric surgery is known as one of the most effective treatments for sustainable weight loss; however, it may be associated with some complications. This study was designed to examine the effects of probiotic supplementation on some morbidities related to this surgery. METHODS: This was a placebo-controlled, double-blind, randomized clinical trial on morbid obese patients referred for One Anastomosis Gastric Bypass- Mini Gastric Bypass (OAGB-MGB) surgery to a tertiary referral center...
May 3, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29690937/concentration-of-25-hydroxyvitamin-d-from-neonatal-dried-blood-spots-and-the-relation-to-gestational-age-birth-weight-and-ponderal-index-the-d-tect-study
#12
Amélie Keller, Mina N Händel, Peder Frederiksen, Ramune Jacobsen, Arieh S Cohen, John J McGrath, Berit L Heitmann
Studies have suggested that vitamin D status at birth may be associated with a range of neonatal outcomes. The aim of this study was to assess the association between neonatal 25-hydroxyvitamin D3 (25(OH)D3) concentration and gestational age, birth weight, Ponderal Index and size for gestational age. Neonatal capillary blood stored as dried blood spots was used to assess 25(OH)D3 concentrations among 2686 subjects selected from a random population sub-sample of individuals, born in Denmark from 1 May 1981 to 31 December 2002...
June 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29684027/chronic-calcitriol-supplementation-improves-the-inflammatory-profiles-of-circulating-monocytes-and-the-associated-intestinal-adipose-tissue-alteration-in-a-diet-induced-steatohepatitis-rat-model
#13
Yen-Bo Su, Tzu-Hao Li, Chia-Chang Huang, Hung-Cheng Tsai, Shiang-Fen Huang, Yun-Cheng Hsieh, Ying-Ying Yang, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin
Vitamin D deficiency and up-regulated TNFα-related signals are reported to be involved in abnormalities including intestinal hyper-permeability, bacterial translocation, systemic/portal endotoxemia, intestinal/adipose tissue/hepatic inflammation, and hepatic steatosis in nonalcoholic steatohepatitis (NASH). This study aims to explore the molecular mechanisms and effects of chronic calcitriol [1,25-(OH)2D3, hormonal form of vitamin D] on gut-adipose tissue-liver axis abnormalities using a high-fat diet (HFD)-fed rat model of NASH...
2018: PloS One
https://www.readbyqxmd.com/read/29652820/diet-quality-and-nutrient-intake-of-urban-overweight-and-obese-primarily-african-american-older-adults-with-osteoarthritis
#14
Sevasti Vergis, Linda Schiffer, Tiffany White, Andrew McLeod, Neda Khudeira, Andrew Demott, Marian Fitzgibbon, Susan Hughes, Lisa Tussing-Humphreys
Diet quality may be a unique target for preventing and managing obesity-related osteoarthritis (OA). Using the Healthy Eating Index-2010 (HEI-2010), this study examined the nutrient intake and diet quality of 400 urban overweight and obese primarily African American older adults with self-reported lower extremity OA. Associations between sociodemographic and health-related factors and diet quality were explored. Participants (mean age 67.8 years, SD 5.9) were included. Habitual dietary intake was assessed using a food frequency questionnaire (FFQ)...
April 13, 2018: Nutrients
https://www.readbyqxmd.com/read/29644951/vitamin-d-deficiency-and-insufficiency-among-us-adults-prevalence-predictors-and-clinical-implications
#15
Xuefeng Liu, Ana Baylin, Phillip D Levy
Vitamin D deficiency (VDD) and insufficiency (VDI) are increasing at a global level, and they are associated with increased risk of various diseases. However, little information is available on the prevalence and predictors of VDD and VDI in a representative population of US adults. Serum 25-hydroxyvitamin D (25(OH)D) measurements were collected from 26 010 adults aged ≥18 years from the National Health and Nutrition Examination Survey (NHANES) 2001-2010. Using thresholds recommended by the Endocrine Society, VDD was defined as 25(OH)D<50 nmol/l and VDI as 50≤25(OH)D<75 nmol/l...
April 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29602840/vitamin-d-obesity-and-leptin-in-relation-to-bladder-cancer-incidence-and-survival-prospective-protocol-study
#16
Randi Elin Gislefoss, Jo Steinson Stenehjem, Helga Helseth Hektoen, Bettina Kulle Andreassen, Hilde Langseth, Karol Axcrona, Elisabete Weiderpass, Alison Mondul, Trude Eid Robsahm
INTRODUCTION: Bladder cancer (BC) (including renal pelvis, ureter and urethra) is one of the most common urogenital cancers and the fourth most frequent cancer in men in the USA. In Norway, the incidence of BC has increased over the last decades. The age-standardised incidence rates per 100 000 for 2011-2015 were 53.7 in men and 16.5 in women. Compared to the 5-year period 2006-2010, the percentage increase in incidence was 6.1% in men and 12.3% in women. The recurrence rate of BC is over 50%, the highest recurrence rate of any malignancy...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29576504/multiple-sclerosis
#17
REVIEW
Alan J Thompson, Sergio E Baranzini, Jeroen Geurts, Bernhard Hemmer, Olga Ciccarelli
Multiple sclerosis continues to be a challenging and disabling condition but there is now greater understanding of the underlying genetic and environmental factors that drive the condition, including low vitamin D levels, cigarette smoking, and obesity. Early and accurate diagnosis is crucial and is supported by diagnostic criteria, incorporating imaging and spinal fluid abnormalities for those presenting with a clinically isolated syndrome. Importantly, there is an extensive therapeutic armamentarium, both oral and by infusion, for those with the relapsing remitting form of the disease...
April 21, 2018: Lancet
https://www.readbyqxmd.com/read/29567008/an-obesity-risk-assessment-tool-for-young-children-validity-with-bmi-and-nutrient-values
#18
Marilyn S Townsend, Mical K Shilts, Dennis M Styne, Christiana Drake, Louise Lanoue, Lenna Ontai
OBJECTIVE: Demonstrate validity and reliability for an obesity risk assessment tool for young children targeting families' modifiable home environments. DESIGN: Longitudinal design with data collected over 100 weeks. SETTING: Head Start and the Special Supplemental Nutrition Program for Women, Infants, and Children. PARTICIPANTS: Parent-child pairs (n = 133) provided food behavior assessments; 3 child-modified, 24-hour dietary recalls; 3 ≥ 36-hour activity logs; and measured heights and weights...
March 19, 2018: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29558783/association-of-vitamin-d-levels-and-type-2-diabetes-mellitus-in-asian-indians-is-independent-of-obesity
#19
A Gupta, M Aslam, S Rathi, B K Mishra, S Bhardwaj, R Jhamb, S V Madhu
BACKGROUND: A large proportion of subjects with type 2 diabetes mellitus (T2DM) in India are non-obese. Asian-Indian subjects with diabetes have been shown to have low vitamin D levels. Whether low vitamin D levels and T2DM in Asian-Indians is attributable to the associated obesity as in caucasians is unclear. Hence we studied the association of vitamin D levels and T2DM in Asian-Indians with or without obesity. METHODS: Total of 213 subjects were recruited in four groups, group 1-Non-obese diabetic, group 2-Non-obese non-diabetic, group 3-Obese diabetic and group 4-Obese non-diabetic...
March 20, 2018: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29525513/metabolically-healthy-obesity-vitamin-d-and-all-cause-and-cardiometabolic-mortality-risk-in-nhanes-iii
#20
Banaz Al-Khalidi, Samantha M Kimball, Jennifer L Kuk, Chris I Ardern
BACKGROUND & AIMS: Previous studies assessing the prognosis of metabolically healthy obesity (MHO) have been limited by a lack of a harmonized definition of MHO phenotype. Furthermore, obesity is a risk factor for vitamin D deficiency and low vitamin D status has been associated with a higher risk of mortality; however, few studies have evaluated the joint association between vitamin D, metabolic health phenotype, and mortality risk. Using a harmonized definition, we investigated whether MHO is associated with subsequent all-cause and cardiometabolic mortality, and whether serum 25-hydroxyvitamin D [25(OH)D] modifies these associations...
March 2, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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