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Minimum clinically important difference

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https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#1
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29325423/early-functional-radiological-outcomes-and-satisfaction-rates-of-total-ankle-arthroplasty-in-an-asian-population
#2
Shi Ming Tan, Hamid Rahmatullah Bin Abdul Razak, Inderjeet Singh Rikhraj
BACKGROUND: Few studies have outlined the outcomes and complications in Asians undergoing total ankle arthroplasty. This study reports the functional, radiological outcomes and satisfaction rates in our Asian population. METHODS: Patients who underwent primary total ankle arthroplasty from 2007 to 2013 were recruited. Outcomes evaluated were the AOFAS Ankle-Hindfoot Score (AHS), Visual Analogue Scale(VAS), and the Short Form 36 (SF-36)questionnaire. Outcome scores were collected prospectively up to 2 years...
January 1, 2018: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/29321021/silver-pig-skin-nanocomposites-and-mesenchymal-stem-cells-suitable-antibiofilm-cellular-dressings-for-wound-healing
#3
Mario Alberto Pérez-Díaz, Phaedra Silva-Bermudez, Binisa Jiménez-López, Valentín Martínez-López, Yaaziel Melgarejo-Ramírez, Ana Brena-Molina, Clemente Ibarra, Isabel Baeza, M Esther Martínez-Pardo, M Lourdes Reyes-Frías, Erik Márquez-Gutiérrez, Cristina Velasquillo, Gabriel Martínez-Castañon, Fidel Martinez-Gutierrez, Roberto Sánchez-Sánchez
BACKGROUND: Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often affected by bacterial infection; where biofilm formation is one of the main risks and particularly problematic because it confers protection to microorganisms against antibiotics. One avenue to prevent bacterial colonization of wounds is the use of silver nanoparticles (AgNPs); which have proved to be effective against non-multidrug-resistant and multidrug-resistant bacteria...
January 10, 2018: Journal of Nanobiotechnology
https://www.readbyqxmd.com/read/29319337/reliable-change-and-minimum-clinically-important-difference-mcid-of-the-repeatable-battery-for-the-assessment-of-neuropsychology-status-rbans-in-a-heterogeneous-dementia-sample-support-for-reliable-change-methods-but-not-the-mcid
#4
Megan E O'Connell, Benjamin Gould, Jake Ursenbach, Joe Enright, Debra G Morgan
We compare reliable change scores and recently published anchor-based cutoffs for minimum clinically important difference (MCID) for the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in a sample of patients diagnosed with various forms of dementia. For memory clinic patients with dementia evaluated twice over a one-year interval (N = 53), observed retest RBANS index scores were compared with predicted retest index scores based on regression formulae developed from cognitively healthy older adults...
January 10, 2018: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29315999/long-term-safety-and-efficacy-of-acotiamide-in-functional-dyspepsia-postprandial-distress-syndrome-results-from-the-european-phase-3-open-label-safety-trial
#5
J Tack, J Pokrotnieks, G Urbonas, C Banciu, V Yakusevich, I Bunganic, H Törnblom, Y Kleban, P Eavis, M Tsuchikawa, T Miyagawa
BACKGROUNDS: Acotiamide is a novel acetylcholinesterase inhibitor for treatment of postprandial distress syndrome (PDS) symptoms of functional dyspepsia (FD). This European phase 3 open-label safety trial has been conducted to evaluate the long-term safety of acotiamide and explore the efficacy of acotiamide on PDS symptoms using the validated LPDS, quality of life using SF-36 and SF-NDI, and work productivity using WPAI. METHODS: FD-PDS patients (defined by ROME III criteria) aged ≥18 years with active PDS symptoms and without predominant overlapping symptoms of epigastric pain syndrome and related disorders were enrolled to receive 100 mg acotiamide three times daily for 1 year...
January 8, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29305287/endoscopic-repair-of-partial-thickness-undersurface-tears-of-the-abductor-tendon-clinical-outcomes-with-minimum-2-year-follow-up
#6
David E Hartigan, Itay Perets, Sherwin W Ho, John P Walsh, Leslie C Yuen, Benjamin G Domb
PURPOSE: To report the minimum 2-year outcomes of transtendinous repair of partial-thickness undersurface tears of the abductor tendon using patient-reported outcomes (PROs), visual analog scale (VAS) scores, and patient satisfaction scores. METHODS: All patients who underwent endoscopic transtendinous gluteus medius repair between October 2009 and May 2013 at 1 institution were prospectively evaluated. The exclusion criteria consisted of less than 2 years' follow-up, previous hip surgery, inflammatory arthritis, open surgery, full-thickness abductor tear, and Workers' Compensation patients...
January 2, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29303927/preoperative-prediction-of-lymph-nodal-metastases-in-endometrial-carcinoma-is-it-possible-a-literature-review
#7
Rami Fares, Sean Kehoe, Nazem Shams
BACKGROUND: Lymph node status is one of the most important prognostic factors in endometrial cancer and crucial for deciding adjuvant therapy. OBJECTIVE: The aim of the study was to assess the different models used to predict lymphatic nodal disease. SEARCH STRATEGY: A literature search was conducted to detect the relevant studies. INCLUSION CRITERIA: Relevant papers comparing the preoperative modality with the final histopathological results including randomized clinical trials, case-control studies, and any publications with a minimum of 50 patients in the report...
January 4, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29291254/supportive-periodontal-therapy-spt-for-maintaining-the-dentition-in-adults-treated-for-periodontitis
#8
REVIEW
Carolina Manresa, Elena C Sanz-Miralles, Joshua Twigg, Manuel Bravo
BACKGROUND: Periodontitis is a bacterially-induced, chronic inflammatory disease that destroys the connective tissues and bone that support teeth. Active periodontal treatment aims to reduce the inflammatory response, primarily through eradication of bacterial deposits. Following completion of treatment and arrest of inflammation, supportive periodontal therapy (SPT) is employed to reduce the probability of re-infection and progression of the disease; to maintain teeth without pain, excessive mobility or persistent infection in the long term, and to prevent related oral diseases...
January 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29290132/defining-the-minimum-clinically-important-difference-for-grade-i-degenerative-lumbar-spondylolisthesis-insights-from-the-quality-outcomes-database
#9
Anthony L Asher, Panagiotis Kerezoudis, Praveen V Mummaneni, Erica F Bisson, Steven D Glassman, Kevin T Foley, Jonathan Slotkin, Eric A Potts, Mark E Shaffrey, Christopher I Shaffrey, Domagoj Coric, John J Knightly, Paul Park, Kai-Ming Fu, Clinton J Devin, Kristin R Archer, Silky Chotai, Andrew K Chan, Michael S Virk, Mohamad Bydon
OBJECTIVE Patient-reported outcomes (PROs) play a pivotal role in defining the value of surgical interventions for spinal disease. The concept of minimum clinically important difference (MCID) is considered the new standard for determining the effectiveness of a given treatment and describing patient satisfaction in response to that treatment. The purpose of this study was to determine the MCID associated with surgical treatment for degenerative lumbar spondylolisthesis. METHODS The authors queried the Quality Outcomes Database registry from July 2014 through December 2015 for patients who underwent posterior lumbar surgery for grade I degenerative spondylolisthesis...
January 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29287822/srs-22r-minimum-clinically-important-difference-and-substantial-clinical-benefit-after-adult-lumbar-scoliosis-surgery
#10
Leah Y Carreon, Michael P Kelly, Charles H Crawford, Christine R Baldus, Steven D Glassman, Christopher I Shaffrey, Keith H Bridwell
STUDY DESIGN: Longitudinal cohort. OBJECTIVES: To determine if the minimum clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds for the Scoliosis Research Society-22R (SRS22R) domains in patients with degenerative lumbar scoliosis are similar to those in patients with adult spinal deformity (ASD) with fusions extending into the thoracic spine. SUMMARY OF BACKGROUND DATA: The MCID and SCB thresholds for the SRS22R domains in patients with ASD and adolescent idiopathic scoliosis have been reported...
January 2018: Spine Deformity
https://www.readbyqxmd.com/read/29286825/is-treatment-of-segond-fracture-necessary-with-combined-anterior-cruciate-ligament-reconstruction
#11
Heath P Melugin, Nick R Johnson, Isabella T Wu, Bruce A Levy, Michael J Stuart, Aaron J Krych
BACKGROUND: There is a paucity of clinical information to guide the treatment of a combined anterior cruciate ligament (ACL) tear and Segond fracture. PURPOSE: To compare clinical outcomes, graft failure rates, and activity levels between patients undergoing ACL reconstruction (ACLR) with and without an untreated Segond fracture at a minimum 2-year follow-up. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: This study included a group of patients with a combined ACL tear/untreated Segond fracture that was matched based on age, sex, body mass index, and graft type to a control group of patients with an ACL tear and no Segond fracture...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29284482/outcomes-of-arthroscopic-debridement-of-isolated-ligamentum-teres-tears-using-the-ihot-33
#12
Nicholas Pergaminelis, Jesse Renouf, Camdon Fary, Oren Tirosh, Phong Tran
BACKGROUND: Tears of the Ligamentum Teres are a common cause of groin pain. Tears of the ligament frequently co-exist alongside other bony or labral intra-articular hip lesions, which are also treated at the time of arthroscopy. For this reason, it is often difficult to assess the effect that debridement alone has on improving patient pain and function. This study aims to assess the short-term outcomes of arthroscopic debridement of isolated Ligamentum Teres tears using a validated patient-reported outcome score - the International Hip Outcome Tool (iHOT-33)...
December 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29282120/can-testing-clinical-significance-reduce-false-positive-rates-in-randomized-controlled-trials-a-snap-review
#13
Theophile Bigirumurame, Adetayo S Kasim
OBJECTIVE: The use of minimum clinically important difference in the hypothesis formulation for superiority trials is similar in principle to the concept of non-inferiority or equivalence trial. However, most clinical trials are analysed testing zero clinical difference. Since the minimum clinically important difference is pre-defined for power calculation, it is important to incorporate it in both the hypothesis testing and the interpretation of findings from clinical trials. RESULTS: We reviewed a set of 50 publications (25 with binary outcome, and 25 with survival time outcome)...
December 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29282073/responsiveness-of-clinical-tests-for-people-with-neck-pain
#14
René Jørgensen, Inge Ris, Carsten Juhl, Deborah Falla, Birgit Juul-Kristensen
BACKGROUND: Responsiveness of a clinical test is highly relevant in order to evaluate the effect of a given intervention. However, the responsiveness of clinical tests for people with neck pain has not been adequately evaluated. The objective of the present study was to examine the responsiveness of four clinical tests which are low cost and easy to perform in a clinical setting, including the craniocervical flexion test, cervical active range of movement, test for the cervical extensors and pressure pain threshold testing...
December 28, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29276041/cost-effectiveness-of-posterior-lumbar-interbody-fusion-in-the-japanese-universal-health-insurance-system
#15
Takahito Fujimori, Toshitada Miwa, Motoki Iwasaki, Takenori Oda
BACKGROUND: Globally, the cost-effectiveness of spinal surgery is becoming increasingly important. However, these data are limited to a few countries. The purpose of our study was to examine the cost/quality adjusted life year (cost/QALY) gained for posterior lumbar interbody fusion (PLIF) in the Japanese universal health insurance system. METHODS: Fifty five patients underwent PLIF for lumbar degenerative spinal canal stenosis between July 2013 and September 2015 was included...
December 21, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29248779/decompression-alone-versus-decompression-and-fusion-for-lumbar-degenerative-spondylolisthesis-a-meta-analysis
#16
Zihao Chen, Peigen Xie, Feng Feng, Kishor Chhantyal, Yang Yang, Limin Rong
OBJECTIVE: To compare the effectiveness and safety of decompression alone (D group) with decompression and fusion (DF group) for patients who were diagnosed with lumbar degenerative spondylolisthesis (LDS). METHODS: Electronic databases were searched for relevant studies that compared decompression alone with decompression and fusion for LDS. Then data extraction and quality assessment were conducted, and the extracted data was analyzed by using RevMan 5.3. We used the random effects model for studies which had heterogeneity between them, and for those without heterogeneity, the fixed model was used...
December 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29243999/efficacy-of-intraoperative-epidural-triamcinolone-application-in-lumbar-microdiscectomy-a-matched-control-study
#17
Martin N Stienen, Holger Joswig, Ivan Chau, Marian C Neidert, David Bellut, Thomas Wälchli, Karl Schaller, Oliver P Gautschi
OBJECTIVE The purpose of this study was to investigate whether the intraoperative application of an epidural steroid (ES) on the decompressed nerve root improves short- and midterm subjective and objective clinical outcomes after lumbar microdiscectomy. METHODS This study was a retrospective analysis of a 2-center database including consecutive cases in which patients underwent lumbar microdiscectomy. All patients who received ES application (40 mg triamcinolone, ES group) were matched by age and sex to patients who had not received ES application (control group)...
December 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29243996/validation-of-the-visual-analog-scale-in-the-cervical-spine
#18
Anna MacDowall, Martin Skeppholm, Yohan Robinson, Claes Olerud
OBJECTIVE The visual analog scale (VAS) is frequently used to measure treatment outcome in patients with cervical spine disorders. The minimum clinically important difference (MCID) is the smallest change in a score that has clinical importance to the patient. Although it has been established for other medical fields, knowledge of the VAS MCID for the cervical spine is sparse, and it has rarely been considered in relation to measurement noise. The goals in this study were as follows: 1) to validate the VAS-neck and VAS-arm instruments for the cervical spine (e...
December 15, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29241765/oliveria-decumbens-essential-oil-chemical-compositions-and-antimicrobial-activity-against-the-growth-of-some-clinical-and-standard-strains-causing-infection
#19
Behrooz Alizadeh Behbahani, Farideh Tabatabaei Yazdi, Alireza Vasiee, Seyed Ali Mortazavi
Oliveria decumbens as a valuable medicinal plant is extensively used in traditional medicine. clinical and standard strains causing infection resistance to antimicrobial agents, is one of the important problems in medicine. The aim of this study was to investigate the antibacterial activities and phytochemical analysis of Oliveria decumbens essential oil on the growth of some clinical and standard strains causing infection (Pseudomonas aerogenes, Escherichia coli, Streptococcus pyogenes and Staphylococcus epidermidis)...
December 11, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29231243/neuromuscular-electrical-stimulation-nmes-for-patellofemoral-pain-syndrome
#20
REVIEW
Ana Luiza C Martimbianco, Maria Regina Torloni, Brenda Ng Andriolo, Gustavo Jm Porfírio, Rachel Riera
BACKGROUND: Patellofemoral pain syndrome, now generally referred to as patellofemoral pain (PFP), is one of the most common orthopaedic disorders, characterised by pain in the anterior or retropatellar knee region. Neuromuscular electrical stimulation (NMES) has been proposed generally as a complementary treatment, associated with other interventions such as exercise, or as a single treatment to increase muscle force, reduce knee pain, and improve function. OBJECTIVES: To assess the effects (benefits and harms) of neuromuscular electrical stimulation for people with patellofemoral pain...
December 12, 2017: Cochrane Database of Systematic Reviews
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