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https://www.readbyqxmd.com/read/29868455/association-between-disease-severity-and-calcium-concentration-in-critically-ill-patients-admitted-to-intensive-care-unit
#1
Sarvin Sanaie, Ata Mahmoodpoor, Hadi Hamishehkar, Kamran Shadvar, Nasim Salimi, Majid Montazer, Afshin Iranpour, Elnaz Faramarzi
Background: Hypocalcemia is very common in critically ill patients admitted to ICU. However, its clinical importance and relation to patient's outcome during early days of ICU admission is questionable. Based on the mentioned problem, it seems that calcium assessment is highly important in these patients. The present study aimed at evaluating the relationship between different calcium concentrations (total/ionized/corrected) and disease severity in critically ill patients. Methods: A total of 100 patients admitted to intensive care units of Imam Reza and Shohada hospitals during Feb 2014 and Apr 2016 were enrolled in this prospective trial...
February 2018: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/29858537/clinical-characteristics-and-severity-of-influenza-infections-by-virus-type-subtype-and-lineage-a-systematic-literature-review
#2
Saverio Caini, Madelon Kroneman, Therese Wiegers, Clotilde El Guerche-Séblain, John Paget
AIM: Studies carried out in the early 2000s found that the number of influenza-associated hospitalizations and deaths was highest in seasons dominated by A(H3N2), suggesting that the clinical presentation and severity of influenza may differ across virus types, subtypes and lineages. We aimed to review the studies that examined this hypothesis. METHOD: We conducted a literature review of studies published until January 2017 that compared the clinical presentation, disease severity, and case-fatality ratio of influenza patients infected with different virus types (A, B), subtypes (pre-pandemic A(H1N1), A(H1N1)p, A(H3N2)) and lineages (Victoria, Yamagata)...
June 2, 2018: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/29845614/risk-factors-for-intensive-care-unit-acquired-weakness-a-systematic-review-and-meta-analysis
#3
REVIEW
Tao Yang, Zhiqiang Li, Li Jiang, Yinhua Wang, Xiuming Xi
Intensive care unit-acquired weakness (ICUAW) occurs frequently in the context of critical illness without alternative plausible cause and specific treatment options, and it is important to identify and summarize the independent risk factors for ICUAW. PubMed, Embase, Central, China Biological Medicine, China National Knowledge Infrastructure, VIP and Wanfang databases were searched from database inception until 10 July 2017. Prospective cohort studies on adult ICU patients who were diagnosed with ICUAW using either clinical or electrophysiological criteria were selected...
May 29, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29807651/persistent-inflammation-immunosuppression-and-catabolism-and-the-development-of-chronic-critical-illness-after-surgery
#4
REVIEW
Philip A Efron, Alicia M Mohr, Azra Bihorac, Hiroyuki Horiguchi, McKenzie K Hollen, Mark S Segal, Henry V Baker, Christiaan Leeuwenburgh, Lyle L Moldawer, Frederick A Moore, Scott C Brakenridge
As early as the 1990s, chronic critical illness, a distinct syndrome of persistent high-acuity illness requiring management in the ICU, was reported under a variety of descriptive terms including the "neuropathy of critical illness," "myopathy of critical illness," "ICU-acquired weakness," and most recently "post-intensive care unit syndrome." The widespread implementation of targeted shock resuscitation, improved organ support modalities, and evidence-based protocolized ICU care has resulted in significantly decreased in-hospital mortality within surgical ICUs, specifically by reducing early multiple organ failure deaths...
May 25, 2018: Surgery
https://www.readbyqxmd.com/read/29748138/defining-new-barriers-to-mobilisation-in-a-highly-active-intensive-care-unit-have-we-found-the-ceiling-an-observational-study
#5
Christopher Brock, Vince Marzano, Margot Green, Jiali Wang, Teresa Neeman, Imogen Mitchell, Bernie Bissett
BACKGROUND: Mobilisation of intensive care (ICU) patients attenuates ICU-acquired weakness, but the prevalence is low (12-54%). Better understanding of barriers and enablers may inform practice. OBJECTIVES: To identify barriers to mobilisation and factors associated with successful mobilisation in our medical /surgical /trauma ICU where mobilisation is well-established. METHODS: 4-week prospective study of frequency and intensity of mobilisation, clinical factors and barriers (extracted from electronic database)...
May 7, 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29747562/early-ambulation-in-patients-with-external-ventricular-drains-results-of-a-quality-improvement-project
#6
Syed Omar Shah, Jacqueline Kraft, Nethra Ankam, Paula Bu, Kristen Stout, Sara Melnyk, Fred Rincon, M Kamran Athar
INTRODUCTION: Prolonged immobility in patients in the intensive care unit (ICU) can lead to muscle wasting and weakness, longer hospital stays, increased number of days in restraints, and hospital-acquired infections. Increasing evidence demonstrates the safety and feasibility of early mobilization in the ICU. However, there is a lack of evidence in the safety and feasibility of mobilizing patients with external ventricular drains (EVDs). The purpose of this study was to determine the safety and feasibility of early mobility in this patient population...
June 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29739651/nurses-reflections-about-caring-for-critically-ill-non-sedated-and-mechanically-ventilated-critically-ill-patients
#7
Ranveig Lind, Hilde-Irén Liland, Berit S Brinchmann, Inga Akeren
OBJECTIVE: The objective was to explore ICU nurses' experiences of caring for non-sedated, critically ill mechanically ventilated patients, when following a study protocol as part of a clinical trial. DESIGN: The study had a qualitative design with twelve nurses participating in two focus groups. The interviews were analysed using a thematic approach. FINDINGS: One overall theme emerged, "Cautious optimism", which suggests positive experiences but with a negative undertone...
May 5, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29729659/improving-health-care-for-critically-ill-patients-using-an-evidence-based-collaborative-approach-to-abcdef-bundle-dissemination-and-implementation
#8
Mary Ann Barnes-Daly, Brenda T Pun, Lori A Harmon, Diane G Byrum, Vishakha K Kumar, John W Devlin, Joanna L Stollings, Kathleen A Puntillo, Heidi J Engel, Patricia J Posa, Juliana Barr, William D Schweickert, Cheryl L Esbrook, Ken D Hargett, Shannon S Carson, J Matthew Aldrich, E Wesley Ely, Michele C Balas
BACKGROUND: Patients admitted to intensive care units (ICUs) often experience pain, oversedation, prolonged mechanical ventilation, delirium, and weakness. These conditions are important in that they often lead to protracted physical, neurocognitive, and mental health sequelae now termed postintensive care syndrome. Changing current ICU practice will not only require the adoption of evidence-based interventions but the development of effective and reliable teams to support these new practices...
May 5, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29727365/evaluating-muscle-mass-in-survivors-of-acute-respiratory-distress-syndrome-a-1-year-multicenter-longitudinal-study
#9
Kitty S Chan, Marina Mourtzakis, Lisa Aronson Friedman, Victor D Dinglas, Catherine L Hough, E Wesley Ely, Peter E Morris, Ramona O Hopkins, Dale M Needham
OBJECTIVES: Rapid muscle wasting occurs during acute respiratory failure, resulting in muscle weakness and functional impairments. This study examines survivors' body composition in the year after acute respiratory distress syndrome and tests associations of patient characteristics, hospital exposures, and survivors' strength and physical functioning with whole body percent lean mass. DESIGN: Prospective cohort study with 6- and 12-month follow-up. SETTING: National study enrolling patients from five study centers...
May 4, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29716425/early-prediction-of-intensive-care-unit-acquired-weakness-a-multicenter-external-validation-study
#10
Esther Witteveen, Luuk Wieske, Juultje Sommers, Jan-Jaap Spijkstra, Monique C de Waard, Henrik Endeman, Saskia Rijkenberg, Wouter de Ruijter, Mengalvio Sleeswijk, Camiel Verhamme, Marcus J Schultz, Ivo N van Schaik, Janneke Horn
OBJECTIVES: An early diagnosis of intensive care unit-acquired weakness (ICU-AW) is often not possible due to impaired consciousness. To avoid a diagnostic delay, we previously developed a prediction model, based on single-center data from 212 patients (development cohort), to predict ICU-AW at 2 days after ICU admission. The objective of this study was to investigate the external validity of the original prediction model in a new, multicenter cohort and, if necessary, to update the model...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29703636/mobilisation-is-feasible-in-intensive-care-patients-receiving-vasoactive-therapy-an-observational-study
#11
Anneke Rebel, Vince Marzano, Margot Green, Karlee Johnston, Jiali Wang, Teresa Neeman, Imogen Mitchell, Bernie Bissett
BACKGROUND: Mobilisation of intensive care unit (ICU) patients reduces ICU-acquired weakness and is associated with better functional outcomes. However, the prevalence of mobilisation of ICU patients remains low. A known barrier to mobilisation is haemodynamic instability, frequently with patients requiring vasoactive therapy. There is a lack of published data to guide clinicians about the safety and feasibility of mobilising patients receiving vasoactive therapy. OBJECTIVES: To describe our mobilisation practice in ICU patients receiving vasoactive therapy and identify factors associated with mobilisation and adverse events...
April 24, 2018: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29665800/mda-5-associated-rapidly-progressive-interstitial-lung-disease-with-recurrent-pneumothoraces-a-case-report
#12
Safi Alqatari, Peter Riddell, Sinead Harney, Michael Henry, Grainne Murphy
BACKGROUND: Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should be ordered. Anti-MDA-5 antibodies was reported in literature to be associated with severe and rapidly progressive interstitial lung disease, with few case reports of pneumothorax and/or pneumomediastinum...
April 17, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29663999/-analysis-of-high-risk-factors-of-intensive-care-unit-acquired-weakness-in-patients-with-sepsis
#13
Xiaofan Yu, Xiaohong Wan, Linjun Wan, Qingqing Huang
OBJECTIVE: To investigate high risk factors of intensive care unit-acquired weakness (ICUAW) in patients with sepsis. METHODS: A retrospective study was conducted. 164 patients with mechanical ventilation (MV) who were diagnosed sepsis and multiple organ dysfunction syndrome (MODS), admitted to intensive care unit (ICU) of the Second Affiliated Hospital of Kunming Medical University from January 1st, 2015 to September 30th, 2017 were enrolled. The general situation, the basic diseases (hypertension, diabetes), body mass index (BMI), protopathy diseases, the level of albumin before ICU admission, the MV time, whether to use glucocorticoid and continuous renal replacement therapy (CRRT) or not, nutrition supply (nutritional way, nutrition initiation time, amino acid/protein supply, nutritional status on ICU 3 days and 7 days), myoglobin, the length of ICU stay, the length of hospital stay, and acute physiology and chronic health evaluation II (APACHE II) score were collected...
April 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29660670/efficacy-of-early-passive-tilting-in-minimizing-icu-acquired-weakness-a-randomized-controlled-trial
#14
Céline Sarfati, Alex Moore, Catherine Pilorge, Priscilla Amaru, Paula Mendialdua, Emilie Rodet, François Stéphan, Saïda Rezaiguia-Delclaux
No abstract text is available yet for this article.
April 5, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29659093/oral-intake-evaluation-in-patients-following-critical-illness-an-icu-cohort-study
#15
Rebecca J Jarden, Lynsey Sutton-Smith, Catherine Boulton
Timely and adequate nutrition improves health outcomes for the critically ill patient. Despite clinical guidelines recommending early oral nutrition, survivors of critical illness experience significant nutritional deficits. This cohort study evaluates the oral nutrition intake in intensive care unit (ICU) patients who have experienced recent critical illness. The oral nutrition intake of a convenience sample of ICU patients post-critical illness was observed during a 1-month period. Data pertaining to both the amount of oral nutrition intake and factors impacting optimal oral nutrition intake were collected and analysed...
April 16, 2018: Nursing in Critical Care
https://www.readbyqxmd.com/read/29624594/a-systematic-scoping-review-on-the-consequences-of-stress-related-hyperglycaemia
#16
Elena Olariu, Nicholas Pooley, Aurélie Danel, Montserrat Miret, Jean-Charles Preiser
BACKGROUND: Stress-related hyperglycaemia (SHG) is commonly seen in acutely ill patients and has been associated with poor outcomes in many studies performed in different acute care settings. We aimed to review the available evidence describing the associations between SHG and different outcomes in acutely ill patients admitted to an ICU. Study designs, populations, and outcome measures used in observational studies were analysed. METHODS: We conducted a systematic scoping review of observational studies following the Joanna Briggs methodology...
2018: PloS One
https://www.readbyqxmd.com/read/29611399/effect-of-central-line-bundle-compliance-on-central-line-associated-bloodstream-infections
#17
Kyoung Hwa Lee, Nan Hyoung Cho, Su Jin Jeong, Mi Na Kim, Sang Hoon Han, Young Goo Song
PURPOSE: The present study aimed to evaluate the effect of central line (CL) bundle compliance on central line-associated bloodstream infections (CLABSIs) in different departments of the same hospital, including the intensive care unit (ICU) and other departments. MATERIALS AND METHODS: The four components of the CL bundle were hand hygiene, use of maximal sterile barrier precautions, chlorhexidine use, and selection of an appropriate site for venous access. Compliance of the CL bundle and CLABSIs were measured for every department [emergency room (ER), ICU, general ward (GW), and operating room (OR)]...
May 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29595563/one-year-outcomes-in-patients-with-acute-respiratory-distress-syndrome-enrolled-in-a-randomized-clinical-trial-of-helmet-versus-facemask-noninvasive-ventilation
#18
Bhakti K Patel, Krysta S Wolfe, Erica L MacKenzie, Dhafer Salem, Cheryl L Esbrook, Amy J Pawlik, Megan Stulberg, Crystal Kemple, Megan Teele, Erin Zeleny, Julia Macleod, Anne S Pohlman, Jesse B Hall, John P Kress
OBJECTIVES: Many survivors of acute respiratory distress syndrome have poor long-term outcomes possibly due to supportive care practices during "invasive" mechanical ventilation. Helmet noninvasive ventilation in acute respiratory distress syndrome may reduce intubation rates; however, it is unknown if avoiding intubation with helmet noninvasive ventilation alters the consequences of surviving acute respiratory distress syndrome. DESIGN: Long-term follow-up data from a previously published randomized controlled trial...
March 27, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29594318/adrenal-crisis-after-first-infusion-of-zoledronic-acid-a-case-report
#19
M Smrecnik, Z Kavcic Trsinar, T Kocjan
Patients with Addison's disease are at greater risk of having reduced bone mineral density and hip fractures and are thus more likely to receive a bisphosphonate than their peers. Potent intravenous bisphosphonates could provoke an acute phase reaction. An 80-year-old female with Addison's disease received her first infusion of zoledronic acid for osteoporosis at our outpatient clinic around noon. Despite doubling her usual afternoon hydrocortisone dose, she became feverish, nauseous, extremely weak, and hypotensive over the night...
March 28, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29584447/inspiratory-muscle-rehabilitation-in-critically-ill-adults-a-systematic-review-and-meta-analysis
#20
Stefannie Vorona, Umberto Sabatini, Sulaiman Al-Maqbali, Michele Bertoni, Martin Dres, Bernie Bissett, Frank Van Haren, A Daniel Martin, Cristian Urrea, Debbie Brace, Matteo Parotto, Margaret S Herridge, Neill K J Adhikari, Eddy Fan, Luana T Melo, W Darlene Reid, Laurent J Brochard, Niall D Ferguson, Ewan C Goligher
RATIONALE: Respiratory muscle weakness is common in critically ill patients; the role of targeted inspiratory muscle training (IMT) in intensive care unit rehabilitation strategies remains poorly defined. OBJECTIVES: The primary objective of the present study was to describe the range and tolerability of published methods for IMT. The secondary objectives were to determine whether IMT improves respiratory muscle strength and clinical outcomes in critically ill patients...
June 2018: Annals of the American Thoracic Society
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