keyword
https://read.qxmd.com/read/38508691/evaluation-of-efficacy-of-2-extended-release-bupivacaine-products-in-a-porcine-model-of-incisional-pain
#21
JOURNAL ARTICLE
Peggy Yang, Stephanie Yang, Laura B Durham, Patrick A Lester, Daniel D Myers
Extended-release (ER) local anesthetics are often incorporated in multi-modal analgesia or as an alternative when the effect of systemic analgesics may confound research. In this study, we compared the analgesic efficacy of 2 ER bupivacaine anesthetics with different ER mechanisms, a slow-release bupivacaine-meloxicam polymer (BMP) and a sucrose acetate isobutyrate bupivacaine (SABER-B) system. We used a full-thickness unilateral skin incision porcine model to evaluate the efficacy of these 2 ER bupivacaine analgesics...
March 20, 2024: Journal of the American Association for Laboratory Animal Science: JAALAS
https://read.qxmd.com/read/38497041/corrigendum-ultrastructural-characteristics-of-neuronal-death-and-white-matter-injury-in-mouse-brain-tissues-after-intracerebral-hemorrhage-coexistence-of-ferroptosis-autophagy-and-necrosis
#22
Qian Li, Abigail Weiland, Xuemei Chen, Xi Lan, Xiaoning Han, Frederick Durham, Xi Liu, Jieru Wan, Wendy C Ziai, Daniel F Hanley, Jian Wang
[This corrects the article DOI: 10.3389/fneur.2018.00581.].
2024: Frontiers in Neurology
https://read.qxmd.com/read/38496968/cellulolytic-and-ethanologenic-evaluation-of-heterotermes-indicola-s-gut-associated-bacterial-isolates
#23
JOURNAL ARTICLE
Sana Azhar, Ayesha Aihetasham, Asma Chaudhary, Zawar Hussain, Rahat Abdul Rehman, Ghulam Abbas, Sulaiman Ali Alharbi, Mohammad Javed Ansari, Samina Qamer
Cellulose is the basic component of lignocellulosic biomass (LCB) making it a suitable substrate for bioethanol fermentation. Cellulolytic and ethanologenic bacteria possess cellulases that convert cellulose to glucose, which in turn yields ethanol subsequently. Heterotermes indicola is a subterranean termite that causes destructive damage by consuming wooden structures of infrastructure, LCB products, etc. Prospectively, the study envisioned the screening of cellulolytic and ethanologenic bacteria from the termite gut...
March 12, 2024: ACS Omega
https://read.qxmd.com/read/38496074/autoimmunity-and-cancer-two-stations-on-the-same-continuum
#24
JOURNAL ARTICLE
Inês Soldin, Nídia Pereira
INTRODUCTION: Autoimmunity has been associated with different types of cancer, including hematological malignancies like lymphomas, and solid tumors. Additionally, the potential role of medication-induced immunosuppression should be considered. AIM: Our study aimed to investigate the relationship between autoimmunity and the development of cancer, as well as the impact of immunosuppressive drugs on increasing cancer risk. METHODS: The study sample was composed of patients who developed cancer after the administration of biological agents for the treatment of autoimmune disorders...
February 2024: Curēus
https://read.qxmd.com/read/38483366/five-year-longitudinal-follow-up-of-restorative-neurostimulation-shows-durability-of-effectiveness-in-patients-with-refractory-chronic-low-back-pain-associated-with-multifidus-muscle-dysfunction
#25
JOURNAL ARTICLE
Christopher Gilligan, Willem Volschenk, Marc Russo, Matthew Green, Christopher Gilmore, Vivek Mehta, Kristiaan Deckers, Kris De Smedt, Usman Latif, Dawood Sayed, Peter Georgius, Jonathan Gentile, Bruce Mitchell, Meredith Langhorst, Frank Huygen, Ganesan Baranidharan, Vikas Patel, Eugene Mironer, Edgar Ross, Alexios Carayannopoulos, Salim Hayek, Ashish Gulve, Jean-Pierre Van Buyten, Antoine Tohmeh, Jeffrey Fischgrund, Shivanand Lad, Farshad Ahadian, Timothy Deer, William Klemme, Richard Rauck, James Rathmell, Greg Maislin, Jan Pieter Heemels, Sam Eldabe
BACKGROUND: Adults with refractory, mechanical chronic low back pain associated with impaired neuromuscular control of the lumbar multifidus muscle have few treatment options that provide long-term clinical benefit. This study hypothesized that restorative neurostimulation, a rehabilitative treatment that activates the lumbar multifidus muscles to overcome underlying dysfunction, is safe and provides relevant and durable clinical benefit to patients with this specific etiology. MATERIALS AND METHODS: In this prospective five-year longitudinal follow-up of the ReActiv8-B pivotal trial, participants (N = 204) had activity-limiting, moderate-to-severe, refractory, mechanical chronic low back pain, a positive prone instability test result indicating impaired multifidus muscle control, and no indications for spine surgery...
March 11, 2024: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/38483251/microlearning-a-concept-analysis
#26
JOURNAL ARTICLE
Jessica Cronin, Marianne L Durham
With an overall rise in technology adoption, the information-seeking behaviors of today have become instant and single-focused, and demand convenience for learning and the acquisition of knowledge. Digital technologies expand the reach of learning and allow for the development of innovative and creative methods of teaching. The use of microlearning has been gaining popularity in academic and professional development settings and corporate training. Currently, there is no standardized definition of microlearning...
March 14, 2024: Computers, Informatics, Nursing: CIN
https://read.qxmd.com/read/38483174/nasal-allergen-neutralizing-antibodies-correlate-closely-with-tolerated-intranasal-allergen-challenge-dose-following-grass-pollen-subcutaneous-immunotherapy-in-patients-with-local-allergic-rhinitis
#27
JOURNAL ARTICLE
Ibon Eguiluz-Gracia, Rebecca V Parkin, Janice A Layhadi, Elizabeth Palmer, Xun Meng, Rongfei Zhu, Umit Sahiner, Stephen R Durham, Maria Jose Torres, Cristobalina Mayorga, Carmen Rondon, Mohamed H Shamji
BACKGROUND: Local allergic rhinitis (LAR) is defined by chronic nasal symptoms, absence of atopy, positive nasal allergen challenge (NAC) and a good response to subcutaneous allergen immunotherapy (SCIT). We sought to investigate SCIT capacity to induce local and systemic blocking antibodies in LAR patients. METHODS: A RDBPC study of grass SCIT was performed, with participants receiving either SCIT (Group A; n = 10) or placebo (Group B; n = 14) in the first 6 months...
March 14, 2024: Allergy
https://read.qxmd.com/read/38483170/gender-differences-in-the-pediatric-neurosurgical-workforce-professional-practice-work-life-balance-and-beyond
#28
JOURNAL ARTICLE
Leeat Granek, Logan Muzyka, Natalie Limoges, Lorraine Kelley-Quon, Jessica Lane, Joseph Ha, Deborah L Benzil, Susan Durham
BACKGROUND AND OBJECTIVES: Evidence suggests that female neurosurgeons experience unique challenges in the workplace including lack of academic advancement, challenges with work-life balance, harassment, and discrimination. How these factors influence the gender gap in neurosurgery remains unclear. This analysis investigated gender differences in pediatric neurosurgeons in professional and nonprofessional activities and responsibilities. METHODS: A survey examining professional activities, work-life balance, family dynamics, career satisfaction, and workplace discrimination and harassment was administered to 495 pediatric neurosurgeons...
March 14, 2024: Neurosurgery
https://read.qxmd.com/read/38457722/observation-of-cabibbo-suppressed-two-body-hadronic-decays-and-precision-mass-measurement-of-the-%C3%AE-_-c-0-baryon
#29
JOURNAL ARTICLE
R Aaij, A S W Abdelmotteleb, C Abellan Beteta, F Abudinén, T Ackernley, B Adeva, M Adinolfi, P Adlarson, H Afsharnia, C Agapopoulou, C A Aidala, Z Ajaltouni, S Akar, K Akiba, P Albicocco, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, P Alvarez Cartelle, R Amalric, S Amato, J L Amey, Y Amhis, L An, L Anderlini, M Andersson, A Andreianov, P Andreola, M Andreotti, D Andreou, D Ao, F Archilli, A Artamonov, M Artuso, E Aslanides, M Atzeni, B Audurier, D Bacher, I Bachiller Perea, S Bachmann, M Bachmayer, J J Back, A Bailly-Reyre, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista de Souza Leite, M Barbetti, I R Barbosa, R J Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, J M Basels, G Bassi, B Batsukh, A Battig, A Bay, A Beck, M Becker, F Bedeschi, I B Bediaga, A Beiter, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Benane, G Bencivenni, E Ben-Haim, A Berezhnoy, R Bernet, S Bernet Andres, D Berninghoff, H C Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, J Bex, Ia Bezshyiko, J Bhom, L Bian, M S Bieker, N V Biesuz, P Billoir, A Biolchini, M Birch, F C R Bishop, A Bitadze, A Bizzeti, M P Blago, T Blake, F Blanc, J E Blank, S Blusk, D Bobulska, V Bocharnikov, J A Boelhauve, O Boente Garcia, T Boettcher, A Bohare, A Boldyrev, C S Bolognani, R Bolzonella, N Bondar, F Borgato, S Borghi, M Borsato, J T Borsuk, S A Bouchiba, T J V Bowcock, A Boyer, C Bozzi, M J Bradley, S Braun, A Brea Rodriguez, N Breer, J Brodzicka, A Brossa Gonzalo, J Brown, D Brundu, A Buonaura, L Buonincontri, A T Burke, C Burr, A Bursche, A Butkevich, J S Butter, J Buytaert, W Byczynski, S Cadeddu, H Cai, R Calabrese, L Calefice, S Cali, M Calvi, M Calvo Gomez, J Cambon Bouzas, P Campana, D H Campora Perez, A F Campoverde Quezada, S Capelli, L Capriotti, A Carbone, L Carcedo Salgado, R Cardinale, A Cardini, P Carniti, L Carus, A Casais Vidal, R Caspary, G Casse, M Cattaneo, G Cavallero, V Cavallini, S Celani, J Cerasoli, D Cervenkov, A J Chadwick, I Chahrour, M G Chapman, M Charles, Ph Charpentier, C A Chavez Barajas, M Chefdeville, C Chen, S Chen, A Chernov, S Chernyshenko, V Chobanova, S Cholak, M Chrzaszcz, A Chubykin, V Chulikov, P Ciambrone, M F Cicala, X Cid Vidal, G Ciezarek, P Cifra, P E L Clarke, M Clemencic, H V Cliff, J Closier, J L Cobbledick, C Cocha Toapaxi, V Coco, J Cogan, E Cogneras, L Cojocariu, P Collins, T Colombo, A Comerma-Montells, L Congedo, A Contu, N Cooke, I Corredoira, A Correia, G Corti, J J Cottee Meldrum, B Couturier, D C Craik, M Cruz Torres, R Currie, C L Da Silva, S Dadabaev, L Dai, X Dai, E Dall'Occo, J Dalseno, C D'Ambrosio, J Daniel, A Danilina, P d'Argent, A Davidson, J E Davies, A Davis, O De Aguiar Francisco, J de Boer, K De Bruyn, S De Capua, M De Cian, U De Freitas Carneiro Da Graca, E De Lucia, J M De Miranda, L De Paula, M De Serio, D De Simone, P De Simone, F De Vellis, J A de Vries, C T Dean, F Debernardis, D Decamp, V Dedu, L Del Buono, B Delaney, H-P Dembinski, V Denysenko, O Deschamps, F Dettori, B Dey, P Di Nezza, I Diachkov, S Didenko, S Ding, V Dobishuk, A D Docheva, A Dolmatov, C Dong, A M Donohoe, F Dordei, A C Dos Reis, L Douglas, A G Downes, W Duan, P Duda, M W Dudek, L Dufour, V Duk, P Durante, M M Duras, J M Durham, D Dutta, A Dziurda, A Dzyuba, S Easo, E Eckstein, U Egede, A Egorychev, V Egorychev, C Eirea Orro, S Eisenhardt, E Ejopu, S Ek-In, L Eklund, M Elashri, J Ellbracht, S Ely, A Ene, E Epple, S Escher, J Eschle, S Esen, T Evans, F Fabiano, L N Falcao, Y Fan, B Fang, L Fantini, M Faria, K Farmer, S Farry, D Fazzini, L Felkowski, M Feng, M Feo, M Fernandez Gomez, A D Fernez, F Ferrari, L Ferreira Lopes, F Ferreira Rodrigues, S Ferreres Sole, M Ferrillo, M Ferro-Luzzi, S Filippov, R A Fini, M Fiorini, M Firlej, K M Fischer, D S Fitzgerald, C Fitzpatrick, T Fiutowski, F Fleuret, M Fontana, F Fontanelli, L F Foreman, R Forty, D Foulds-Holt, M Franco Sevilla, M Frank, E Franzoso, G Frau, C Frei, D A Friday, L Frontini, J Fu, Q Fuehring, Y Fujii, T Fulghesu, E Gabriel, G Galati, M D Galati, A Gallas Torreira, D Galli, S Gambetta, M Gandelman, P Gandini, H Gao, R Gao, Y Gao, Y Gao, M Garau, L M Garcia Martin, P Garcia Moreno, J García Pardiñas, B Garcia Plana, F A Garcia Rosales, L Garrido, C Gaspar, R E Geertsema, L L Gerken, E Gersabeck, M Gersabeck, T Gershon, L Giambastiani, F I Giasemis, V Gibson, H K Giemza, A L Gilman, M Giovannetti, A Gioventù, P Gironella Gironell, C Giugliano, M A Giza, K Gizdov, E L Gkougkousis, F C Glaser, V V Gligorov, C Göbel, E Golobardes, D Golubkov, A Golutvin, A Gomes, S Gomez Fernandez, F Goncalves Abrantes, M Goncerz, G Gong, J A Gooding, I V Gorelov, C Gotti, J P Grabowski, L A Granado Cardoso, E Graugés, E Graverini, L Grazette, G Graziani, A T Grecu, L M Greeven, N A Grieser, L Grillo, S Gromov, C Gu, M Guarise, M Guittiere, V Guliaeva, P A Günther, A-K Guseinov, E Gushchin, Y Guz, T Gys, T Hadavizadeh, C Hadjivasiliou, G Haefeli, C Haen, J Haimberger, S C Haines, M Hajheidari, T Halewood-Leagas, M M Halvorsen, P M Hamilton, J Hammerich, Q Han, X Han, S Hansmann-Menzemer, L Hao, N Harnew, T Harrison, M Hartmann, C Hasse, M Hatch, J He, K Heijhoff, F Hemmer, C Henderson, R D L Henderson, A M Hennequin, K Hennessy, L Henry, J Herd, J Heuel, A Hicheur, D Hill, M Hilton, S E Hollitt, J Horswill, R Hou, Y Hou, N Howarth, J Hu, J Hu, W Hu, X Hu, W Huang, X Huang, W Hulsbergen, R J Hunter, M Hushchyn, D Hutchcroft, P Ibis, M Idzik, D Ilin, P Ilten, A Inglessi, A Iniukhin, A Ishteev, K Ivshin, R Jacobsson, H Jage, S J Jaimes Elles, S Jakobsen, E Jans, B K Jashal, A Jawahery, V Jevtic, E Jiang, X Jiang, Y Jiang, Y J Jiang, M John, D Johnson, C R Jones, T P Jones, S Joshi, B Jost, N Jurik, I Juszczak, D Kaminaris, S Kandybei, Y Kang, M Karacson, D Karpenkov, M Karpov, A M Kauniskangas, J W Kautz, F Keizer, D M Keller, M Kenzie, T Ketel, B Khanji, A Kharisova, S Kholodenko, G Khreich, T Kirn, V S Kirsebom, O Kitouni, S Klaver, N Kleijne, K Klimaszewski, M R Kmiec, S Koliiev, L Kolk, A Kondybayeva, A Konoplyannikov, P Kopciewicz, R Kopecna, P Koppenburg, M Korolev, I Kostiuk, O Kot, S Kotriakhova, A Kozachuk, P Kravchenko, L Kravchuk, M Kreps, S Kretzschmar, P Krokovny, W Krupa, W Krzemien, J Kubat, S Kubis, W Kucewicz, M Kucharczyk, V Kudryavtsev, E Kulikova, A Kupsc, B K Kutsenko, D Lacarrere, G Lafferty, A Lai, A Lampis, D Lancierini, C Landesa Gomez, J J Lane, R Lane, C Langenbruch, J Langer, O Lantwin, T Latham, F Lazzari, C Lazzeroni, R Le Gac, S H Lee, R Lefèvre, A Leflat, S Legotin, O Leroy, T Lesiak, B Leverington, A Li, H Li, K Li, L Li, P Li, P-R Li, S Li, T Li, T Li, Y Li, Z Li, Z Lian, X Liang, C Lin, T Lin, R Lindner, V Lisovskyi, R Litvinov, G Liu, H Liu, K Liu, Q Liu, S Liu, Y Liu, A Lobo Salvia, A Loi, J Lomba Castro, T Long, I Longstaff, J H Lopes, A Lopez Huertas, S López Soliño, G H Lovell, Y Lu, C Lucarelli, D Lucchesi, S Luchuk, M Lucio Martinez, V Lukashenko, Y Luo, A Lupato, E Luppi, K Lynch, X-R Lyu, R Ma, S Maccolini, F Machefert, F Maciuc, I Mackay, V Macko, L R Madhan Mohan, M M Madurai, A Maevskiy, D Maisuzenko, M W Majewski, J J Malczewski, S Malde, B Malecki, A Malinin, T Maltsev, G Manca, G Mancinelli, C Mancuso, R Manera Escalero, D Manuzzi, C A Manzari, D Marangotto, J F Marchand, U Marconi, S Mariani, C Marin Benito, J Marks, A M Marshall, P J Marshall, G Martelli, G Martellotti, L Martinazzoli, M Martinelli, D Martinez Santos, F Martinez Vidal, A Massafferri, M Materok, R Matev, A Mathad, V Matiunin, C Matteuzzi, K R Mattioli, A Mauri, E Maurice, J Mauricio, M Mazurek, M McCann, L Mcconnell, T H McGrath, N T McHugh, A McNab, R McNulty, B Meadows, G Meier, D Melnychuk, M Merk, A Merli, L Meyer Garcia, D Miao, H Miao, M Mikhasenko, D A Milanes, M Milovanovic, M-N Minard, A Minotti, E Minucci, T Miralles, S E Mitchell, B Mitreska, D S Mitzel, A Modak, A Mödden, R A Mohammed, R D Moise, S Mokhnenko, T Mombächer, M Monk, I A Monroy, S Monteil, G Morello, M J Morello, M P Morgenthaler, J Moron, A B Morris, A G Morris, R Mountain, H Mu, Z M Mu, E Muhammad, F Muheim, M Mulder, K Müller, D Murray, R Murta, P Naik, T Nakada, R Nandakumar, T Nanut, I Nasteva, M Needham, N Neri, S Neubert, N Neufeld, P Neustroev, R Newcombe, J Nicolini, D Nicotra, E M Niel, S Nieswand, N Nikitin, P Nogga, N S Nolte, C Normand, J Novoa Fernandez, G Nowak, C Nunez, H N Nur, A Oblakowska-Mucha, V Obraztsov, T Oeser, S Okamura, R Oldeman, F Oliva, M Olocco, C J G Onderwater, R H O'Neil, J M Otalora Goicochea, T Ovsiannikova, P Owen, A Oyanguren, O Ozcelik, K O Padeken, B Pagare, P R Pais, T Pajero, A Palano, M Palutan, G Panshin, L Paolucci, A Papanestis, M Pappagallo, L L Pappalardo, C Pappenheimer, C Parkes, B Passalacqua, G Passaleva, A Pastore, M Patel, J Patoc, C Patrignani, C J Pawley, A Pellegrino, M Pepe Altarelli, S Perazzini, D Pereima, A Pereiro Castro, P Perret, A Perro, K Petridis, A Petrolini, S Petrucci, H Pham, A Philippov, L Pica, M Piccini, B Pietrzyk, G Pietrzyk, D Pinci, F Pisani, M Pizzichemi, V Placinta, M Plo Casasus, F Polci, M Poli Lener, A Poluektov, N Polukhina, I Polyakov, E Polycarpo, S Ponce, D Popov, S Poslavskii, K Prasanth, L Promberger, C Prouve, V Pugatch, V Puill, G Punzi, H R Qi, W Qian, N Qin, S Qu, R Quagliani, B Rachwal, J H Rademacker, R Rajagopalan, M Rama, M Ramírez García, M Ramos Pernas, M S Rangel, F Ratnikov, G Raven, M Rebollo De Miguel, F Redi, J Reich, F Reiss, Z Ren, P K Resmi, R Ribatti, G R Ricart, S Ricciardi, K Richardson, M Richardson-Slipper, K Rinnert, P Robbe, G Robertson, E Rodrigues, E Rodriguez Fernandez, J A Rodriguez Lopez, E Rodriguez Rodriguez, D L Rolf, A Rollings, P Roloff, V Romanovskiy, M Romero Lamas, A Romero Vidal, F Ronchetti, M Rotondo, M S Rudolph, T Ruf, R A Ruiz Fernandez, J Ruiz Vidal, A Ryzhikov, J Ryzka, J J Saborido Silva, N Sagidova, N Sahoo, B Saitta, M Salomoni, C Sanchez Gras, I Sanderswood, R Santacesaria, C Santamarina Rios, M Santimaria, L Santoro, E Santovetti, D Saranin, G Sarpis, M Sarpis, A Sarti, C Satriano, A Satta, M Saur, D Savrina, H Sazak, L G Scantlebury Smead, A Scarabotto, S Schael, S Scherl, A M Schertz, M Schiller, H Schindler, M Schmelling, B Schmidt, S Schmitt, O Schneider, A Schopper, M Schubiger, N Schulte, S Schulte, M H Schune, R Schwemmer, G Schwering, B Sciascia, A Sciuccati, S Sellam, A Semennikov, M Senghi Soares, A Sergi, N Serra, L Sestini, A Seuthe, Y Shang, D M Shangase, M Shapkin, I Shchemerov, L Shchutska, T Shears, L Shekhtman, Z Shen, S Sheng, V Shevchenko, B Shi, E B Shields, Y Shimizu, E Shmanin, R Shorkin, J D Shupperd, B G Siddi, R Silva Coutinho, G Simi, S Simone, M Singla, N Skidmore, R Skuza, T Skwarnicki, M W Slater, J C Smallwood, J G Smeaton, E Smith, K Smith, M Smith, A Snoch, L Soares Lavra, M D Sokoloff, F J P Soler, A Solomin, A Solovev, I Solovyev, R Song, Y Song, Y Song, Y S Song, F L Souza De Almeida, B Souza De Paula, E Spadaro Norella, E Spedicato, J G Speer, E Spiridenkov, P Spradlin, V Sriskaran, F Stagni, M Stahl, S Stahl, S Stanislaus, E N Stein, O Steinkamp, O Stenyakin, H Stevens, D Strekalina, Y Su, F Suljik, J Sun, L Sun, Y Sun, P N Swallow, K Swientek, F Swystun, A Szabelski, T Szumlak, M Szymanski, Y Tan, S Taneja, M D Tat, A Terentev, F Teubert, E Thomas, D J D Thompson, H Tilquin, V Tisserand, S T'Jampens, M Tobin, L Tomassetti, G Tonani, X Tong, D Torres Machado, L Toscano, D Y Tou, C Trippl, G Tuci, N Tuning, A Ukleja, D J Unverzagt, E Ursov, A Usachov, A Ustyuzhanin, U Uwer, V Vagnoni, A Valassi, G Valenti, N Valls Canudas, M Van Dijk, H Van Hecke, E van Herwijnen, C B Van Hulse, R Van Laak, M van Veghel, R Vazquez Gomez, P Vazquez Regueiro, C Vázquez Sierra, S Vecchi, J J Velthuis, M Veltri, A Venkateswaran, M Vesterinen, D Vieira, M Vieites Diaz, X Vilasis-Cardona, E Vilella Figueras, A Villa, P Vincent, F C Volle, D Vom Bruch, V Vorobyev, N Voropaev, K Vos, C Vrahas, J Walsh, E J Walton, G Wan, C Wang, G Wang, J Wang, J Wang, J Wang, J Wang, M Wang, N W Wang, R Wang, X Wang, Y Wang, Z Wang, Z Wang, Z Wang, J A Ward, N K Watson, D Websdale, Y Wei, B D C Westhenry, D J White, M Whitehead, A R Wiederhold, D Wiedner, G Wilkinson, M K Wilkinson, I Williams, M Williams, M R J Williams, R Williams, F F Wilson, W Wislicki, M Witek, L Witola, C P Wong, G Wormser, S A Wotton, H Wu, J Wu, Y Wu, K Wyllie, S Xian, Z Xiang, Y Xie, A Xu, J Xu, L Xu, L Xu, M Xu, Z Xu, Z Xu, Z Xu, D Yang, S Yang, X Yang, Y Yang, Z Yang, Z Yang, V Yeroshenko, H Yeung, H Yin, C Y Yu, J Yu, X Yuan, E Zaffaroni, M Zavertyaev, M Zdybal, M Zeng, C Zhang, D Zhang, J Zhang, L Zhang, S Zhang, S Zhang, Y Zhang, Y Zhang, Y Zhao, A Zharkova, A Zhelezov, Y Zheng, T Zhou, X Zhou, Y Zhou, V Zhovkovska, L Z Zhu, X Zhu, X Zhu, Z Zhu, V Zhukov, J Zhuo, Q Zou, S Zucchelli, D Zuliani, G Zunica
The first observation of the singly Cabibbo-suppressed Ω_{c}^{0}→Ω^{-}K^{+} and Ω_{c}^{0}→Ξ^{-}π^{+} decays is reported, using proton-proton collision data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5.4  fb^{-1}, collected with the LHCb detector between 2016 and 2018. The branching fraction ratios are measured to be B(Ω_{c}^{0}→Ω^{-}K^{+})/B(Ω_{c}^{0}→Ω^{-}π^{+})=[6...
February 23, 2024: Physical Review Letters
https://read.qxmd.com/read/38457697/enhanced-production-of-%C3%AE-_-b-0-baryons-in-high-multiplicity-pp-collisions-at-sqrt-s-13%C3%A2-%C3%A2-tev
#30
JOURNAL ARTICLE
R Aaij, A S W Abdelmotteleb, C Abellan Beteta, F Abudinén, T Ackernley, B Adeva, M Adinolfi, P Adlarson, C Agapopoulou, C A Aidala, Z Ajaltouni, S Akar, K Akiba, P Albicocco, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, P Alvarez Cartelle, R Amalric, S Amato, J L Amey, Y Amhis, L An, L Anderlini, M Andersson, A Andreianov, P Andreola, M Andreotti, D Andreou, A A Anelli, D Ao, F Archilli, M Argenton, S Arguedas Cuendis, A Artamonov, M Artuso, E Aslanides, M Atzeni, B Audurier, D Bacher, I Bachiller Perea, S Bachmann, M Bachmayer, J J Back, A Bailly-Reyre, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista de Souza Leite, M Barbetti, I R Barbosa, R J Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, J M Basels, G Bassi, B Batsukh, A Battig, A Bay, A Beck, M Becker, F Bedeschi, I B Bediaga, A Beiter, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Benane, G Bencivenni, E Ben-Haim, A Berezhnoy, J L M Berkey, R Bernet, S Bernet Andres, H C Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, J Bex, Ia Bezshyiko, J Bhom, M S Bieker, N V Biesuz, P Billoir, A Biolchini, M Birch, F C R Bishop, A Bitadze, A Bizzeti, M P Blago, T Blake, F Blanc, J E Blank, S Blusk, D Bobulska, V Bocharnikov, J A Boelhauve, O Boente Garcia, T Boettcher, A Bohare, A Boldyrev, C S Bolognani, R Bolzonella, N Bondar, F Borgato, S Borghi, M Borsato, J T Borsuk, S A Bouchiba, T J V Bowcock, A Boyer, C Bozzi, M J Bradley, S Braun, A Brea Rodriguez, N Breer, J Brodzicka, A Brossa Gonzalo, J Brown, D Brundu, A Buonaura, L Buonincontri, A T Burke, C Burr, A Bursche, A Butkevich, J S Butter, J Buytaert, W Byczynski, S Cadeddu, H Cai, R Calabrese, L Calefice, S Cali, M Calvi, M Calvo Gomez, J Cambon Bouzas, P Campana, D H Campora Perez, A F Campoverde Quezada, S Capelli, L Capriotti, R Caravaca-Mora, A Carbone, L Carcedo Salgado, R Cardinale, A Cardini, P Carniti, L Carus, A Casais Vidal, R Caspary, G Casse, J Castro Godinez, M Cattaneo, G Cavallero, V Cavallini, S Celani, J Cerasoli, D Cervenkov, S Cesare, A J Chadwick, I Chahrour, M Charles, Ph Charpentier, C A Chavez Barajas, M Chefdeville, C Chen, S Chen, A Chernov, S Chernyshenko, V Chobanova, S Cholak, M Chrzaszcz, A Chubykin, V Chulikov, P Ciambrone, M F Cicala, X Cid Vidal, G Ciezarek, P Cifra, P E L Clarke, M Clemencic, H V Cliff, J Closier, J L Cobbledick, C Cocha Toapaxi, V Coco, J Cogan, E Cogneras, L Cojocariu, P Collins, T Colombo, A Comerma-Montells, L Congedo, A Contu, N Cooke, I Corredoira, A Correia, G Corti, J J Cottee Meldrum, B Couturier, D C Craik, M Cruz Torres, R Currie, C L Da Silva, S Dadabaev, L Dai, X Dai, E Dall'Occo, J Dalseno, C D'Ambrosio, J Daniel, A Danilina, P d'Argent, A Davidson, J E Davies, A Davis, O De Aguiar Francisco, C De Angelis, J de Boer, K De Bruyn, S De Capua, M De Cian, U De Freitas Carneiro Da Graca, E De Lucia, J M De Miranda, L De Paula, M De Serio, D De Simone, P De Simone, F De Vellis, J A de Vries, F Debernardis, D Decamp, V Dedu, L Del Buono, B Delaney, H-P Dembinski, J Deng, V Denysenko, O Deschamps, F Dettori, B Dey, P Di Nezza, I Diachkov, S Didenko, S Ding, V Dobishuk, A D Docheva, A Dolmatov, C Dong, A M Donohoe, F Dordei, A C Dos Reis, L Douglas, A G Downes, W Duan, P Duda, M W Dudek, L Dufour, V Duk, P Durante, M M Duras, J M Durham, D Dutta, A Dziurda, A Dzyuba, S Easo, E Eckstein, U Egede, A Egorychev, V Egorychev, C Eirea Orro, S Eisenhardt, E Ejopu, S Ek-In, L Eklund, M Elashri, J Ellbracht, S Ely, A Ene, E Epple, S Escher, J Eschle, S Esen, T Evans, F Fabiano, L N Falcao, Y Fan, B Fang, L Fantini, M Faria, K Farmer, D Fazzini, L Felkowski, M Feng, M Feo, M Fernandez Gomez, A D Fernez, F Ferrari, F Ferreira Rodrigues, S Ferreres Sole, M Ferrillo, M Ferro-Luzzi, S Filippov, R A Fini, M Fiorini, M Firlej, K M Fischer, D S Fitzgerald, C Fitzpatrick, T Fiutowski, F Fleuret, M Fontana, F Fontanelli, L F Foreman, R Forty, D Foulds-Holt, M Franco Sevilla, M Frank, E Franzoso, G Frau, C Frei, D A Friday, L Frontini, J Fu, Q Fuehring, Y Fujii, T Fulghesu, E Gabriel, G Galati, M D Galati, A Gallas Torreira, D Galli, S Gambetta, M Gandelman, P Gandini, H Gao, R Gao, Y Gao, Y Gao, Y Gao, M Garau, L M Garcia Martin, P Garcia Moreno, J García Pardiñas, B Garcia Plana, K G Garg, L Garrido, C Gaspar, R E Geertsema, L L Gerken, E Gersabeck, M Gersabeck, T Gershon, Z Ghorbanimoghaddam, L Giambastiani, F I Giasemis, V Gibson, H K Giemza, A L Gilman, M Giovannetti, A Gioventù, P Gironella Gironell, C Giugliano, M A Giza, E L Gkougkousis, F C Glaser, V V Gligorov, C Göbel, E Golobardes, D Golubkov, A Golutvin, A Gomes, S Gomez Fernandez, F Goncalves Abrantes, M Goncerz, G Gong, J A Gooding, I V Gorelov, C Gotti, J P Grabowski, L A Granado Cardoso, E Graugés, E Graverini, L Grazette, G Graziani, A T Grecu, L M Greeven, N A Grieser, L Grillo, S Gromov, C Gu, M Guarise, M Guittiere, V Guliaeva, P A Günther, A-K Guseinov, E Gushchin, Y Guz, T Gys, T Hadavizadeh, C Hadjivasiliou, G Haefeli, C Haen, J Haimberger, M Hajheidari, T Halewood-Leagas, M M Halvorsen, P M Hamilton, J Hammerich, Q Han, X Han, S Hansmann-Menzemer, L Hao, N Harnew, T Harrison, M Hartmann, C Hasse, J He, K Heijhoff, F Hemmer, C Henderson, R D L Henderson, A M Hennequin, K Hennessy, L Henry, J Herd, J Heuel, A Hicheur, D Hill, S E Hollitt, J Horswill, R Hou, Y Hou, N Howarth, J Hu, J Hu, W Hu, X Hu, W Huang, W Hulsbergen, R J Hunter, M Hushchyn, D Hutchcroft, M Idzik, D Ilin, P Ilten, A Inglessi, A Iniukhin, A Ishteev, K Ivshin, R Jacobsson, H Jage, S J Jaimes Elles, S Jakobsen, E Jans, B K Jashal, A Jawahery, V Jevtic, E Jiang, X Jiang, Y Jiang, Y J Jiang, M John, D Johnson, C R Jones, T P Jones, S Joshi, B Jost, N Jurik, I Juszczak, D Kaminaris, S Kandybei, Y Kang, M Karacson, D Karpenkov, M Karpov, A M Kauniskangas, J W Kautz, F Keizer, D M Keller, M Kenzie, T Ketel, B Khanji, A Kharisova, S Kholodenko, G Khreich, T Kirn, V S Kirsebom, O Kitouni, S Klaver, N Kleijne, K Klimaszewski, M R Kmiec, S Koliiev, L Kolk, A Konoplyannikov, P Kopciewicz, P Koppenburg, M Korolev, I Kostiuk, O Kot, S Kotriakhova, A Kozachuk, P Kravchenko, L Kravchuk, M Kreps, S Kretzschmar, P Krokovny, W Krupa, W Krzemien, J Kubat, S Kubis, W Kucewicz, M Kucharczyk, V Kudryavtsev, E Kulikova, A Kupsc, B K Kutsenko, D Lacarrere, G Lafferty, A Lai, A Lampis, D Lancierini, C Landesa Gomez, J J Lane, R Lane, C Langenbruch, J Langer, O Lantwin, T Latham, F Lazzari, C Lazzeroni, R Le Gac, S H Lee, R Lefèvre, A Leflat, S Legotin, M Lehuraux, O Leroy, T Lesiak, B Leverington, A Li, H Li, K Li, L Li, P Li, P-R Li, S Li, T Li, T Li, Y Li, Y Li, Z Li, Z Lian, X Liang, C Lin, T Lin, R Lindner, V Lisovskyi, R Litvinov, G Liu, H Liu, K Liu, Q Liu, S Liu, Y Liu, Y Liu, Y L Liu, A Lobo Salvia, A Loi, J Lomba Castro, T Long, J H Lopes, A Lopez Huertas, S López Soliño, G H Lovell, C Lucarelli, D Lucchesi, S Luchuk, M Lucio Martinez, V Lukashenko, Y Luo, A Lupato, E Luppi, K Lynch, X-R Lyu, G M Ma, R Ma, S Maccolini, F Machefert, F Maciuc, I Mackay, L R Madhan Mohan, M M Madurai, A Maevskiy, D Magdalinski, D Maisuzenko, M W Majewski, J J Malczewski, S Malde, B Malecki, L Malentacca, A Malinin, T Maltsev, G Manca, G Mancinelli, C Mancuso, R Manera Escalero, D Manuzzi, D Marangotto, J F Marchand, R Marchevski, U Marconi, S Mariani, C Marin Benito, J Marks, A M Marshall, P J Marshall, G Martelli, G Martellotti, L Martinazzoli, M Martinelli, D Martinez Santos, F Martinez Vidal, A Massafferri, M Materok, R Matev, A Mathad, V Matiunin, C Matteuzzi, K R Mattioli, A Mauri, E Maurice, J Mauricio, P Mayencourt, M Mazurek, M McCann, L Mcconnell, T H McGrath, N T McHugh, A McNab, R McNulty, B Meadows, G Meier, D Melnychuk, M Merk, A Merli, L Meyer Garcia, D Miao, H Miao, M Mikhasenko, D A Milanes, A Minotti, E Minucci, T Miralles, S E Mitchell, B Mitreska, D S Mitzel, A Modak, A Mödden, R A Mohammed, R D Moise, S Mokhnenko, T Mombächer, M Monk, I A Monroy, S Monteil, A Morcillo Gomez, G Morello, M J Morello, M P Morgenthaler, J Moron, A B Morris, A G Morris, R Mountain, H Mu, Z M Mu, E Muhammad, F Muheim, M Mulder, K Müller, F Mũnoz-Rojas, R Murta, P Naik, T Nakada, R Nandakumar, T Nanut, I Nasteva, M Needham, N Neri, S Neubert, N Neufeld, P Neustroev, R Newcombe, J Nicolini, D Nicotra, E M Niel, N Nikitin, P Nogga, N S Nolte, C Normand, J Novoa Fernandez, G Nowak, C Nunez, H N Nur, A Oblakowska-Mucha, V Obraztsov, T Oeser, S Okamura, R Oldeman, F Oliva, M Olocco, C J G Onderwater, R H O'Neil, J M Otalora Goicochea, T Ovsiannikova, P Owen, A Oyanguren, O Ozcelik, K O Padeken, B Pagare, P R Pais, T Pajero, A Palano, M Palutan, G Panshin, L Paolucci, A Papanestis, M Pappagallo, L L Pappalardo, C Pappenheimer, C Parkes, B Passalacqua, G Passaleva, D Passaro, A Pastore, M Patel, J Patoc, C Patrignani, C J Pawley, A Pellegrino, M Pepe Altarelli, S Perazzini, D Pereima, A Pereiro Castro, P Perret, A Perro, K Petridis, A Petrolini, S Petrucci, H Pham, L Pica, M Piccini, B Pietrzyk, G Pietrzyk, D Pinci, F Pisani, M Pizzichemi, V Placinta, M Plo Casasus, F Polci, M Poli Lener, A Poluektov, N Polukhina, I Polyakov, E Polycarpo, S Ponce, D Popov, S Poslavskii, K Prasanth, L Promberger, C Prouve, V Pugatch, V Puill, G Punzi, H R Qi, W Qian, N Qin, S Qu, R Quagliani, R I Rabadan Trejo, B Rachwal, J H Rademacker, M Rama, M Ramírez García, M Ramos Pernas, M S Rangel, F Ratnikov, G Raven, M Rebollo De Miguel, F Redi, J Reich, F Reiss, Z Ren, P K Resmi, R Ribatti, G R Ricart, D Riccardi, S Ricciardi, K Richardson, M Richardson-Slipper, K Rinnert, P Robbe, G Robertson, E Rodrigues, E Rodriguez Fernandez, J A Rodriguez Lopez, E Rodriguez Rodriguez, A Rogovskiy, D L Rolf, A Rollings, P Roloff, V Romanovskiy, M Romero Lamas, A Romero Vidal, G Romolini, F Ronchetti, M Rotondo, S R Roy, M S Rudolph, T Ruf, M Ruiz Diaz, R A Ruiz Fernandez, J Ruiz Vidal, A Ryzhikov, J Ryzka, J J Saborido Silva, R Sadek, N Sagidova, N Sahoo, B Saitta, M Salomoni, C Sanchez Gras, I Sanderswood, R Santacesaria, C Santamarina Rios, M Santimaria, L Santoro, E Santovetti, A Saputi, D Saranin, G Sarpis, M Sarpis, A Sarti, C Satriano, A Satta, M Saur, D Savrina, H Sazak, L G Scantlebury Smead, A Scarabotto, S Schael, S Scherl, A M Schertz, M Schiller, H Schindler, M Schmelling, B Schmidt, S Schmitt, H Schmitz, O Schneider, A Schopper, N Schulte, S Schulte, M H Schune, R Schwemmer, G Schwering, B Sciascia, A Sciuccati, S Sellam, A Semennikov, M Senghi Soares, A Sergi, N Serra, L Sestini, A Seuthe, Y Shang, D M Shangase, M Shapkin, I Shchemerov, L Shchutska, T Shears, L Shekhtman, Z Shen, S Sheng, V Shevchenko, B Shi, E B Shields, Y Shimizu, E Shmanin, R Shorkin, J D Shupperd, R Silva Coutinho, G Simi, S Simone, N Skidmore, R Skuza, T Skwarnicki, M W Slater, J C Smallwood, E Smith, K Smith, M Smith, A Snoch, L Soares Lavra, M D Sokoloff, F J P Soler, A Solomin, A Solovev, I Solovyev, R Song, Y Song, Y Song, Y S Song, F L Souza De Almeida, B Souza De Paula, E Spadaro Norella, E Spedicato, J G Speer, E Spiridenkov, P Spradlin, V Sriskaran, F Stagni, M Stahl, S Stahl, S Stanislaus, E N Stein, O Steinkamp, O Stenyakin, H Stevens, D Strekalina, Y Su, F Suljik, J Sun, L Sun, Y Sun, P N Swallow, K Swientek, F Swystun, A Szabelski, T Szumlak, M Szymanski, Y Tan, S Taneja, M D Tat, A Terentev, F Terzuoli, F Teubert, E Thomas, D J D Thompson, H Tilquin, V Tisserand, S T'Jampens, M Tobin, L Tomassetti, G Tonani, X Tong, D Torres Machado, L Toscano, D Y Tou, C Trippl, G Tuci, N Tuning, L H Uecker, A Ukleja, D J Unverzagt, E Ursov, A Usachov, A Ustyuzhanin, U Uwer, V Vagnoni, A Valassi, G Valenti, N Valls Canudas, H Van Hecke, E van Herwijnen, C B Van Hulse, R Van Laak, M van Veghel, R Vazquez Gomez, P Vazquez Regueiro, C Vázquez Sierra, S Vecchi, J J Velthuis, M Veltri, A Venkateswaran, M Vesterinen, D Vieira, M Vieites Diaz, X Vilasis-Cardona, E Vilella Figueras, A Villa, P Vincent, F C Volle, D Vom Bruch, V Vorobyev, N Voropaev, K Vos, G Vouters, C Vrahas, J Walsh, E J Walton, G Wan, C Wang, G Wang, J Wang, J Wang, J Wang, J Wang, M Wang, N W Wang, R Wang, X Wang, X W Wang, Y Wang, Z Wang, Z Wang, Z Wang, J A Ward, N K Watson, D Websdale, Y Wei, B D C Westhenry, D J White, M Whitehead, A R Wiederhold, D Wiedner, G Wilkinson, M K Wilkinson, M Williams, M R J Williams, R Williams, F F Wilson, W Wislicki, M Witek, L Witola, C P Wong, G Wormser, S A Wotton, H Wu, J Wu, Y Wu, K Wyllie, S Xian, Z Xiang, Y Xie, A Xu, J Xu, L Xu, L Xu, M Xu, Z Xu, Z Xu, Z Xu, D Yang, S Yang, X Yang, Y Yang, Z Yang, Z Yang, V Yeroshenko, H Yeung, H Yin, C Y Yu, J Yu, X Yuan, E Zaffaroni, M Zavertyaev, M Zdybal, M Zeng, C Zhang, D Zhang, J Zhang, L Zhang, S Zhang, S Zhang, Y Zhang, Y Zhang, Y Z Zhang, Y Zhao, A Zharkova, A Zhelezov, X Z Zheng, Y Zheng, T Zhou, X Zhou, Y Zhou, V Zhovkovska, L Z Zhu, X Zhu, X Zhu, Z Zhu, V Zhukov, J Zhuo, Q Zou, D Zuliani, G Zunica
The production rate of Λ_{b}^{0} baryons relative to B^{0} mesons in pp collisions at a center-of-mass energy sqrt[s]=13  TeV is measured by the LHCb experiment. The ratio of Λ_{b}^{0} to B^{0} production cross sections shows a significant dependence on both the transverse momentum and the measured charged-particle multiplicity. At low multiplicity, the ratio measured at LHCb is consistent with the value measured in e^{+}e^{-} collisions, and increases by a factor of ∼2 with increasing multiplicity...
February 23, 2024: Physical Review Letters
https://read.qxmd.com/read/38457051/low-self-perceived-need-for-prep-and-behavioral-indications-of-msm-who-recently-refused-daily-prep-a-mixed-methods-study-in-three-u-s-cities
#31
JOURNAL ARTICLE
Krishna Kiran Kota, Deborah Gelaude, Neal Carnes, Alisú Schoua-Glusberg, Paula M Frew, Laura Randall, Bryan Gale, Valerie Betley, Gordon Mansergh
Pre-exposure prophylaxis (PrEP) reduces sexual risk for HIV transmission by 99% when used appropriately, but remains underutilized among gay, bisexual, and other men who have sex with men (MSM). In this mixed-method study, we describe reasons for PrEP refusal associated with low self-perceived need for PrEP among MSM who recently declined daily oral PrEP when offered by a provider. Data are from a quantitative behavioral survey of MSM (N = 93) living in Atlanta, Chicago, and Raleigh-Durham, who also either responded to an in-depth interview (n = 51) or participated in one of 12 focus groups (n = 42)...
March 8, 2024: AIDS and Behavior
https://read.qxmd.com/read/38450530/cell-free-dna-from-nail-clippings-as-source-of-normal-control-for-genomic-studies-in-hematologic-malignancies
#32
JOURNAL ARTICLE
Melissa Krystel-Whittemore, Kseniya Petrova-Drus, Ryan N Ptashkin, Mark D Ewalt, JinJuan Yao, Ying Liu, Menglei Zhu, Jamal Benhamida, Benjamin Durham, Jyoti Kumar, Khedoudja Nafa, Iwona Kiecka, Anita S Bowman, Erika Gedvilaite, Jacklyn Casanova, Yun-Te Lin, Abhinita S Mohanty, Satshil Rana, Anoop Balakrishnan Rema, Ivelise Rijo, Nelio Chaves, Paulo Salazar, Anita Yun, Sean Lachhander, Wei Wang, Mohammad S Haque, Wenbin Xiao, Mikhail Roshal, Sergio Giralt, Gilles Salles, Raajit Rampal, Eytan M Stein, Miguel-Angel Perales, Steven Horwitz, Ann Jakubowski, Doris Ponce, Alina Markova, Ozge Birsoy, Diana Mandelker, Simon Mantha, Ahmet Dogan, Ryma Benayed, Marc Ladanyi, Michael F Berger, A Rose Brannon, Ahmet Zehir, Chad Vanderbilt, Maria E Arcila
Comprehensive genomic sequencing is becoming a critical component in the assessment of hematologic malignancies, with broad implications for patient management. In this context, unequivocally discriminating somatic from germline events is challenging but greatly facilitated by matched analysis of tumor:normal pairs. In contrast to solid tumors, conventional sources of normal control (peripheral blood, buccal swabs, saliva) could be highly involved by the neoplastic process, rendering them unsuitable. In this work we describe our real-world experience using cell free DNA (cfDNA) isolated from nail clippings as an alternate source of normal control, through the dedicated review of 2,610 tumor:nail pairs comprehensively sequenced by MSK-IMPACT-heme...
March 7, 2024: Haematologica
https://read.qxmd.com/read/38449762/blame-framing-and-prior-knowledge-influence-moral-judgments-for-people-involved-in-the-tulsa-race-massacre-among-a-combined-oklahoma-and-uk-sample
#33
JOURNAL ARTICLE
Justin D Durham, Adon F G Rosen, Scott D Gronlund
INTRODUCTION: How an event is framed impacts how people judge the morality of those involved, but prior knowledge can influence information processing about an event, which also can impact moral judgments. The current study explored how blame framing and self-reported prior knowledge of a historical act of racial violence, labeled as Riot, Massacre, or Event, impacted individual's cumulative moral judgments regarding the groups involved in the Tulsa Race Massacre (Black Tulsans, the Tulsa Police, and White Tulsans)...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38446263/circulating-n-lactoyl-amino-acids-and-n-formyl-methionine-reflect-mitochondrial-dysfunction-and-predict-mortality-in-septic-shock
#34
JOURNAL ARTICLE
Robert S Rogers, Rohit Sharma, Hardik B Shah, Owen S Skinner, Xiaoyan A Guo, Apekshya Panda, Rahul Gupta, Timothy J Durham, Kelsey B Shaughnessy, Jared R Mayers, Kathryn A Hibbert, Rebecca M Baron, B Taylor Thompson, Vamsi K Mootha
INTRODUCTION: Sepsis is a highly morbid condition characterized by multi-organ dysfunction resulting from dysregulated inflammation in response to acute infection. Mitochondrial dysfunction may contribute to sepsis pathogenesis, but quantifying mitochondrial dysfunction remains challenging. OBJECTIVE: To assess the extent to which circulating markers of mitochondrial dysfunction are increased in septic shock, and their relationship to severity and mortality. METHODS: We performed both full-scan and targeted (known markers of genetic mitochondrial disease) metabolomics on plasma to determine markers of mitochondrial dysfunction which distinguish subjects with septic shock (n = 42) from cardiogenic shock without infection (n = 19), bacteremia without sepsis (n = 18), and ambulatory controls (n = 19) - the latter three being conditions in which mitochondrial function, proxied by peripheral oxygen consumption, is presumed intact...
March 6, 2024: Metabolomics: Official Journal of the Metabolomic Society
https://read.qxmd.com/read/38442920/patient-derived-tumor-xenograft-study-with-cdk4-6-inhibitor-plus-akt-inhibitor-for-the-management-of-metastatic-castration-resistant-prostate-cancer
#35
JOURNAL ARTICLE
Adam M Kase, Justyna Gleba, James L Miller, Erin Miller, Joachim Petit, Michael T Barrett, Yumei Zhou, Ephraim E Parent, Hancheng Cai, Joshua A Knight, Jacob Orme, Jordan Reynolds, William F Durham, Thomas M Metz, Nathalie Meurice, Brandy Edenfield, Aylin Alasonyalilar Demirer, Ahmet Bilgili, Peyton G Hickman, Matthew L Pawlush, Laura Marlow, Daniel P Wickland, Winston Tan, John A Copland
Metastatic castration-resistant prostate cancer (mCRPC) is an aggressive malignancy with poor outcomes. To investigate novel therapeutic strategies, we characterized three new metastatic prostate cancer PDTX models and developed 3D spheroids from each to investigate molecular targeted therapy combinations including CDK4/6 inhibitors (CDK4/6i) with AKT inhibitors (ATKi). Metastatic prostate cancer tissue was collected and three PDTX models were established and characterized using WES. PDTX 3-D spheroids were developed from these three PDTXs to show resistance patterns and test novel molecular targeted therapies...
March 6, 2024: Molecular Cancer Therapeutics
https://read.qxmd.com/read/38442704/implementation-of-low-intensity-thrombolysis-monitoring-care-in-routine-practice-process-evaluation-of-the-optimal-post-rtpa-iv-monitoring-in-acute-ischemic-stroke-optimistmain-study-in-the-united-states
#36
JOURNAL ARTICLE
Menglu Ouyang, Francisca González, Michelle Montalbano, April Pruski, Stephen Jan, Xia Wang, Brenda Johnson, Debbie V Summers, Pooja Khatri, Alejandra Malavera, Michael Iacobelli, Roland Faigle, Paula Munoz-Venturelli, Francisca Urrutia Goldsack, Diana Day, Thompson G Robinson, Alice C Durham, Ahtasam Ebraimo, Lili Song, Yi Sui, Wan Asyraf Wan Zaidi, Richard I Lindley, Candice Delcourt, Victor Cruz Urrutia, Craig S Anderson, Hueiming Liu
INTRODUCTION: The ongoing OPTIMISTmain study, an international, multicenter, stepped-wedge cluster randomized trial, aims to determine effectiveness and safety of low-intensity versus standard monitoring in thrombolysis-treated patients with mild-to-moderate acute ischemic stroke (AIS). An embedded process evaluation explored integration and impact of the intervention on care processes at participating US sites. METHODS: A mixed-methods approach with quantitative and qualitative data were collected between September 2021 and November 2022...
March 5, 2024: Cerebrovascular Diseases
https://read.qxmd.com/read/38437382/designing-a-muon-scattering-scanner-for-nuclear-debris-measurement
#37
JOURNAL ARTICLE
Haruo Miyadera, Tsukasa Sugita, Takuro Fujimaki, Yuki Nakai, Kyohei Noguchi, Yudhitya Kusumawati, Shuji Yamamoto, Souichi Ueno, Naoto Kume, Kenji Kurihara, Masaki Yoda, Christopher L Morris, Elena Guardincerri, J Matthew Durham, Dan Poulson
Removal of fuel debris is planned to start at Unit 2 of the Fukushima Daiichi Nuclear Power Plant. During the removal, it is desirable to distinguish fuel debris from radioactive wastes and to sort the fuel debris accordingly to the amounts of nuclear material contained. Muon scattering tomography invented at Los Alamos in the early 2000s is highly sensitivity to high-atomic-number materials such as uranium. A muon scanner to sort the debris is designed and currently in production. One of the challenges is to operate the muon scanner in the presence of high γ -ray radiations from the debris: muon-event-identification electronics and a muon-tracking algorithm in the presence of high γ -ray radiations were developed...
February 20, 2024: Applied Optics
https://read.qxmd.com/read/38434614/a-baker-s-dozen-of-top-antimicrobial-stewardship-intervention-publications-in-2022
#38
REVIEW
Reagan K Barfield, Matthew L Brown, Benjamin Albrecht, Katie E Barber, Jeannette Bouchard, Amy L Carr, Elias B Chahine, David Cluck, Elizabeth W Covington, Connor R Deri, Spencer H Durham, Carmen Faulkner-Fennell, Lauren K Freeman, Timothy P Gauthier, Geneen M Gibson, Sarah B Green, Athena L V Hobbs, Bruce M Jones, Caroline C Jozefczyk, Ashley H Marx, Edoabasi U McGee, Lacie J McKamey, Rachel Musgrove, Emily Perez, Douglas Slain, Kayla R Stover, Michelle S Turner, Cyle White, P Brandon Bookstaver, Christopher M Bland
Keeping abreast of the antimicrobial stewardship-related articles published each year is challenging. The Southeastern Research Group Endeavor identified antimicrobial stewardship-related, peer-reviewed literature that detailed an actionable intervention during 2022. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight actionable interventions used by antimicrobial stewardship programs to capture potentially effective strategies for local implementation...
March 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38433681/school-shootings-in-the-united-states-1997-2022
#39
JOURNAL ARTICLE
Luke J Rapa, Antonis Katsiyannis, Samantha N Scott, Olivia Durham
OBJECTIVES: Gun violence in the United States is a public health crisis. In 2019, gun injury became the leading cause of death among children aged birth to 19 years. Moreover, the United States has had 57 times as many school shootings as all other major industrialized nations combined. The purpose of this study was to understand the frequency of school-related gun violence across a quarter century, considering both school shootings and school mass shootings. METHODS: We drew on 2 publicly available datasets whose data allowed us to tabulate the frequency of school shootings and school mass shootings...
April 1, 2024: Pediatrics
https://read.qxmd.com/read/38432178/a-cross-sectional-investigation-of-the-factors-associated-with-awareness-of-pep-and-prep-among-queensland-university-students
#40
JOURNAL ARTICLE
Sarah Warzywoda, Amalie Dyda, Lisa Fitzgerald, Amy Mullens, Joseph Debattista, Jo Durham, Zhihong Gu, Kathryn Wenham, Armin Ariana, Charles F Gilks, Sara F E Bell, Judith A Dean
OBJECTIVE: University creates unique social environments for many young people that can result in behaviour changes that can impact sexual health-related risks and facilitate transmission of HIV. Little is known about HIV knowledge, risk, and awareness of pre-exposure prophylaxis/post-exposure prophylaxis (PrEP/PEP) among Australian university students. METHODS: A 2019 online survey distributed through Queensland universities, using active recruitment/snowball sampling...
March 2, 2024: Australian and New Zealand Journal of Public Health
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