keyword
MENU ▼
Read by QxMD icon Read
search

Durham

keyword
https://www.readbyqxmd.com/read/28742444/queering-biology-gutting-feminism-a-review-essay-of-gut-feminism-by-elizabeth-a-wilson-durham-nc-duke-university-press-2015
#1
David A Rubin
The author reviews Elizabeth A. Wilson's Gut Feminism (2015), arguing that Wilson's book productively challenges some of feminist theory's most entrenched presuppositions: that social, cultural, and discursive frameworks are opposed and superior to biological ones; that biological matter is flat, sovereign, monolithic, and determining; that depression is more a cultural, historical, and psychological phenomenon than a biochemical and pharmaceutical one (and that these nominative distinctions are stable and natural); and finally, that the belly's ruminations (hunger, ingestion, digestion, peristalsis, diarrhea, constipation, and excretion) give no clue as to the complexities of entanglements between gut, psyche, subjectivity, sociality, and hostility...
July 25, 2017: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/28741999/deakozyma-yunnanensis-sp-nov-a-novel-yeast-species-isolated-from-rotten-wood
#2
Jun Zheng, Kai-Fang Liu, Xiao-Jing Liu, Lin Zhang, Feng-Li Hui
Three strains representing a novel yeast species were isolated from rotten wood samples collected in Xishuangbanna Tropical Rainforest in Yunnan Province, PR China. Sequence analysis of the D1/D2 domains of the large subunit (LSU) rRNA gene and the internal transcribed spacer (ITS) regions indicated that the novel species represented a member of the genus Deakozyma. The novel species was related most closely to the type strain of Deakozyma indianensis but they differed by 5.8 % sequence divergence (20 substitutions and 5 gaps) in the D1/D2 domain and by 12...
July 21, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28738112/central-role-of-protein-kinase-a-in-promoting-trigeminal-nociception-in-an-in-vivo-model-of-temporomandibular-disorders
#3
Lindsey K Koop, Jordan L Hawkins, Lauren E Cornelison, Paul L Durham
AIMS: To investigate cellular changes in the spinal trigeminal nucleus (STN) and trigeminal ganglion (TG) associated with trigeminal nociception mediated by inflammation in the temporomandibular joint (TMJ). METHODS: Male Sprague-Dawley rats (n = 86) were utilized to investigate cellular and behavioral responses to prolonged TMJ inflammation caused by bilateral injection of Complete Freund's Adjuvant (CFA) in the TMJ capsules. To investigate the cellular effects of protein kinase A (PKA) in the STN, rats were injected intrathecally with the selective PKA inhibitor KT5720 prior to injection of CFA into both TMJ capsules...
July 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28733386/mir-99-regulates-normal-and-malignant-hematopoietic-stem-cell-self-renewal
#4
Mona Khalaj, Carolien M Woolthuis, Wenhuo Hu, Benjamin H Durham, S Haihua Chu, Sarah Qamar, Scott A Armstrong, Christopher Y Park
The microRNA-99 (miR-99) family comprises a group of broadly conserved microRNAs that are highly expressed in hematopoietic stem cells (HSCs) and acute myeloid leukemia stem cells (LSCs) compared with their differentiated progeny. Herein, we show that miR-99 regulates self-renewal in both HSCs and LSCs. miR-99 maintains HSC long-term reconstitution activity by inhibiting differentiation and cell cycle entry. Moreover, miR-99 inhibition induced LSC differentiation and depletion in an MLL-AF9-driven mouse model of AML, leading to reduction in leukemia-initiating activity and improved survival in secondary transplants...
July 21, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28728527/antiretroviral-nonadherence-and-condomless-sex-in-the-hiv-outpatient-study-usa-2007-2014
#5
M D Durham, R Hart, K Buchacz, J Hammer, B Young, D Yang, K Wood, B Yangco, J T Brooks
Effective antiretroviral therapy (ART) reduces plasma HIV RNA viral load (VL) to undetectable levels and its effectiveness depends on consistent adherence. Consistent adherence and use of safe sex practices may substantially decrease the risk of HIV transmission. We sought to explore the potential association between self-reported nonadherence to ART and engaging in unsafe sexual practices capable of transmitting HIV. Using clinical and audio computer-assisted self-interview data from the prospective HIV Outpatient Study from 2007 to 2014, we assessed the frequency of self-reported ART nonadherence during the three days prior to the survey among HIV-infected persons in care and factors associated with self-reported ART nonadherence...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28715140/the-natural-history-of-thin-melanoma-and-the-utility-of-sentinel-lymph-node-biopsy
#6
Alison B Durham, Jennifer L Schwartz, Lori Lowe, Lili Zhao, Andrew G Johnson, Kelly L Harms, Christopher K Bichakjian, Amy P Orsini, Scott A McLean, Carol R Bradford, Mark S Cohen, Timothy M Johnson, Michael S Sabel, Sandra L Wong
BACKGROUND AND OBJECTIVES: Current literature may overestimate the risk of nodal metastasis from thin melanoma due to reporting of data only from lesions treated with SLNB. Our objective was to define the natural history of thin melanoma, assessing the likelihood of nodal disease, in order to guide selection for SLNB. METHODS: Retrospective review. The primary outcome was the rate of nodal disease. Clinicopathologic factors were evaluated to find associations with nodal disease...
July 17, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28714772/can-typical-us-home-visits-affect-infant-attachment-preliminary-findings-from-a-randomized-trial-of-healthy-families-durham
#7
Lisa J Berlin, Tiffany L Martoccio, Karen Appleyard Carmody, W Benjamin Goodman, Karen O'Donnell, Janis Williams, Robert A Murphy, Kenneth A Dodge
US government-funded early home visiting services are expanding significantly. The most widely implemented home visiting models target at-risk new mothers and their infants. Such home visiting programs typically aim to support infant-parent relationships; yet, such programs' effects on infant attachment quality per se are as yet untested. Given these programs' aims, and the crucial role of early attachments in human development, it is important to understand attachment processes in home visited families. The current, preliminary study examined 94 high-risk mother-infant dyads participating in a randomized evaluation of the Healthy Families Durham (HFD) home visiting program...
July 17, 2017: Attachment & Human Development
https://www.readbyqxmd.com/read/28714087/clinical-and-pathological-classification-of-canine-intraocular-lymphoma
#8
Matthew R Lanza, Ayla R Musciano, Richard D Dubielzig, Amy C Durham
The objectives of this retrospective study of 100 dogs with intraocular lymphoma were to describe the histomorphologic and immunohistochemical features of canine intraocular lymphoma, determine the proportion of cases with presumed solitary ocular lymphoma (PSOL) compared to multicentric disease, and assess the clinical outcomes of these patients. Selected cases from Penn Vet Diagnostic Laboratory and Comparative Ocular Pathology Lab of Wisconsin (2004-2015) were evaluated and subtyped using the WHO classification system...
July 17, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28710710/interventions-for-increasing-hiv-testing-uptake-in-migrants-a-systematic-review-of-evidence
#9
REVIEW
Eithandee Aung, Sarah J Blondell, Jo Durham
Migrants have been identified as being at greater risk for late HIV testing and diagnosis. Late diagnosis is of concern because timely diagnosis and initiation of treatment can both optimise health outcomes and reduce transmission. We reviewed and evaluated interventions that aimed to increase HIV testing uptake in migrant populations. Of 6511 papers retrieved, 10 met the inclusion criteria and were included in the review. Three types of interventions were identified (exposure to HIV prevention messages, HIV education programs, and direct offer of testing)...
July 14, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28709820/sex-dependent-difference-in-the-relationship-between-adipose-tissue-cholesterol-efflux-and-estradiol-concentrations-in-young-healthy-humans
#10
REVIEW
Fatima Iqbal, William J Durham, Ayyash Melhem, Saleem Raslan, Tony T Tran, Traver J Wright, Rabia Asghar, Ken Fujise, Elena Volpi, Labros Sidossis, Nicola Abate, Melinda Sheffield-Moore, Demidmaa Tuvdendorj
BACKGROUND: Impaired adipose tissue function and lower levels of high density lipoprotein cholesterol (HDL-C) have been implicated in the development of vascular dementia, and metabolic diseases such as hypertension, atherosclerosis, type 2 diabetes (T2D) and metabolic syndrome. Interestingly, both the substrate fluxes in adipose tissue and HDL-C concentration differ between men and women. Moreover, adipose tissue cholesterol efflux has been implicated in modulation of HDL-C levels. Thus, we aimed to determine if the association between serum estradiol levels and adipose tissue cholesterol efflux is sex-dependent...
July 11, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28709033/vegetated-land-cover-near-residence-is-associated-with-reduced-allostatic-load-and-improved-biomarkers-of-neuroendocrine-metabolic-and-immune-functions
#11
Andrey I Egorov, Shannon M Griffin, Reagan R Converse, Jennifer N Styles, Elizabeth A Sams, Anthony Wilson, Laura E Jackson, Timothy J Wade
BACKGROUND: Greater exposure to urban green spaces has been linked to reduced risks of depression, cardiovascular disease, diabetes and premature death. Alleviation of chronic stress is a hypothesized pathway to improved health. Previous studies linked chronic stress with a biomarker-based composite measure of physiological dysregulation known as allostatic load. OBJECTIVE: This study's objective was to assess the relationship between vegetated land cover near residences and allostatic load...
July 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/28707833/-sarcoma-centres-a-necessary-tool-in-the-management-of-patients-and-for-research
#12
Stéphane Cherix, Frédéric Vauclair, Boris Morattel, Matthias Vautrin, Maurice Matter, Michael Montemurro, Antonia Digklia, Igor Letovanec, Patrick Omoumi, François Saucy, Michel Gonzalez, André-Dante Durham, Francesca Bosisio, Anja C Zyska Cherix, Hannes A Rudiger
Sarcomas are rare diseases, the treatment of which requires an appropriate technical plateform and a broad spectrum of multidisciplinary specialists. Many are initially treated by unplanned excision, and then referred to specialized centres. Secondary treatments may lead to higher complication rates and local recurrence, with lower functional outcome, life quality and possibly overall survival. In order to improve the accessibility for referral to a specialist centre, the coordination of clinical and research activities, and the quality of the management of sarcomas in general, Lausanne University Hospital (CHUV) has opened a Sarcoma centre on October 1st 2016...
December 14, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28695323/in-memoriam-anne-campbell-professor-in-psychology-durham-university-consulting-editor-for-human-nature
#13
Catharine Cross
No abstract text is available yet for this article.
July 10, 2017: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/28687232/reduced-need-for-surgery-in-severe-nasal-polyposis-with-mepolizumab-randomised-trial
#14
Claus Bachert, Ana R Sousa, Valerie J Lund, Glenis K Scadding, Philippe Gevaert, Shuaib Nasser, Stephen R Durham, Marjolein E Cornet, Harsha H Kariyawasam, Jane Gilbert, Daren Austin, Aoife C Maxwell, Richard P Marshall, Wytske J Fokkens
BACKGROUND: Patients with eosinophilic nasal polyposis frequently require surgery, and recurrence rates are high. OBJECTIVE: To assess the efficacy and safety of mepolizumab vs placebo for severe bilateral nasal polyposis. METHODS: This randomised, double-blind, placebo-controlled trial recruited patients aged 18-70 years with recurrent nasal polyposis requiring surgery. Patients received intravenous mepolizumab 750 mg or placebo every 4 weeks for a total of six doses, in addition to daily topical corticosteroid treatment...
July 4, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28686768/completeness-of-facial-self-application-of-sunscreen-in-cosmetic-surgery-patients
#15
Nicole A Langelier, Jason Liss, Sandra Stinnett, Julie A Woodward
Previous studies have demonstrated incomplete sunscreen self-application to various facial regions in cosmetic surgery patients, but there is no scientific research on the completeness of facial and periocular sunscreen self-application using ultraviolet (UV) photography for assessment. This prospective, cross-sectional, qualitative study aimed to assess completeness of facial application of sunscreen in oculofacial surgery patients at the Duke Eye Center (Durham, North Carolina). Forty-four participants were enrolled, and completeness of facial sunscreen self-application was assessed using UV photography...
June 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28683102/identification-of-prognostic-collagen-signatures-and-potential-therapeutic-stromal-targets-in-canine-mammary-gland-carcinoma
#16
Ashley Case, Becky K Brisson, Amy C Durham, Suzanne Rosen, James Monslow, Elizabeth Buza, Pascale Salah, Julie Gillem, Gordon Ruthel, Sridhar Veluvolu, Veronica Kristiansen, Ellen Puré, Dorothy C Brown, Karin U Sørenmo, Susan W Volk
Increasing evidence indicates that the tumor microenvironment plays a critical role in regulating the biologic behavior of breast cancer. In veterinary oncology, there is a need for improved prognostic markers to accurately identify dogs at risk for local and distant (metastatic) recurrence of mammary gland carcinoma and therefore would benefit from adjuvant therapy. Collagen density and fiber organization have been shown to regulate tumor progression in both mouse and human mammary tumors, with certain collagen signatures predicting poor outcomes in women with breast cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28679734/high-prevalence-of-myeloid-neoplasms-in-adults-with-non-langerhans-cell-histiocytosis
#17
Matthias Papo, Eli L Diamond, Fleur Cohen-Aubart, Jean-François Emile, Damien Roos-Weil, Nishant Gupta, Benjamin H Durham, Neval Ozkaya, Ahmet Dogan, Gary A Ulaner, Raajit Rampal, Jean-Emmanuel Kahn, Thomas Sené, Frédéric Charlotte, Baptiste Hervier, Caroline Besnard, Olivier A Bernard, Catherine Settegrana, Nathalie Droin, Zofia Hélias-Rodzewicz, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche
Erdheim-Chester Disease (ECD) is a rare non-Langerhans Cell histiocytosis that most commonly affects adults and is driven by a high frequency of mutations in BRAF, MAP2K1, and kinases promoting MAP kinase signaling. Due to the relative rarity of ECD, key clinical features of the disease may not be well defined. Across a multi-institutional cohort of 189 patients with ECD and ECD overlapping with Langerhans Cell Histiocytosis (so-called Mixed Histiocytosis (MH)), we identified an unexpected and heretofore undescribed frequent occurrence of myeloid neoplasms amongst patients with ECD and MH...
July 5, 2017: Blood
https://www.readbyqxmd.com/read/28673330/udp-glucuronosyltransferases-and-biochemical-recurrence-in-prostate-cancer-progression
#18
Delores J Grant, Zinan Chen, Lauren E Howard, Emily Wiggins, Amanda De Hoedt, Adriana C Vidal, Skyla T Carney, Jill Squires, Clara E Magyar, Jiaoti Huang, Stephen J Freedland
BACKGROUND: Uridine 5'-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of testosterone, dihydrotestosterone (DHT), and DHT metabolites in the prostate basal and luminal tissue. The expression of the UGT2B15, UGT2B17, and UGT2B28 enzymes has not been evaluated in prostate tissue samples from hormone therapy-naïve patients. METHODS: We determined the expression of UGT2B15, UGT2B17, and UGT2B28 enzymes in 190 prostate tissue samples from surgical specimens of a multiethnic cohort of patients undergoing radical prostatectomy at the Durham Veterans Affairs Medical Center...
July 3, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28658756/unusual-severe-extra-intestinal-manifestations-of-a-common-enteric-pathogen-aeromonas-spp
#19
Barnini Banerjee, Mridula Madiyal, Lingadakai Ramchandra, Chiranjay Mukhopadhyay, Rahul Garg, Kiran Chawla
INTRODUCTION: Aeromonas spp. are halophilic, Gram-negative bacilli. They are widely distributed in the soil and aquatic environment and have been associated with various extra-intestinal infections, such as skin and soft-tissue infections, meningitis, bacteraemia etc. The most common species associated with extra-intestinal infection is Aeromonas hydrophila. AIM: To get the overview of clinical presentations, underlying predisposing factors associated with the extra-intestinal infections caused by Aeromonas species and their antimicrobial susceptibility pattern...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28649380/gitr-ligand-fusion-protein-agonist-enhances-the-tumor-antigen-specific-cd8-t-cell-response-and-leads-to-long-lasting-memory
#20
Nick M Durham, Nick Holoweckyj, Randall S MacGill, Kelly McGlinchey, Ching Ching Leow, Scott H Robbins
BACKGROUND: The expansion of antigen-specific CD8 T cells is important in generating an effective and long-lasting immune response to tumors and viruses. Glucocorticoid-induced tumor necrosis factor receptor family-related receptor (GITR) is a co-stimulatory receptor that binds the GITR ligand (GITRL). Agonism of GITR can produce important signals that drive expansion of effector T cell populations. METHODS: We explored two separate murine tumor models, CT26 and TC-1, for responsiveness to GITR Ligand Fusion Protein(GITRL-FP) monotherapy...
2017: Journal for Immunotherapy of Cancer
keyword
keyword
57787
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"