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UCLA and HCC

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https://www.readbyqxmd.com/read/21315679/green-tea-consumption-inflammation-and-the-risk-of-primary-hepatocellular-carcinoma-in-a-chinese-population
#1
Yanli Li, Shen-Chih Chang, Binh Y Goldstein, William L Scheider, Lin Cai, Nai-Chieh Y You, Heather P Tarleton, Baoguo Ding, Jinkou Zhao, Ming Wu, Qingwu Jiang, Shunzhang Yu, Jianyu Rao, Qing-Yi Lu, Zuo-Feng Zhang, Lina Mu
OBJECTIVE: Green tea has been found to possess anti-inflammatory, anti-oxidative and anti-carcinogenic properties. The present study examines the association between green tea drinking and hepatocellular carcinoma (HCC) and its interactions with other risk or protective factors and single nucleotide polymorphisms (SNP) of inflammation and oxidative stress related genes. METHODS: A population-based case-control study with 204 primary HCC cases and 415 healthy controls was conducted in Taixing, China...
August 2011: Cancer Epidemiology
https://www.readbyqxmd.com/read/20225256/serum-ferritin-concentration-predicts-mortality-in-patients-awaiting-liver-transplantation
#2
MULTICENTER STUDY
Nicole M Walker, Katherine A Stuart, Rebecca J Ryan, Shireena Desai, Sammy Saab, Jennifer A Nicol, Linda M Fletcher, Darrell H G Crawford
UNLABELLED: Additional markers are required to identify patients on the orthotopic liver transplant (OLT) waiting list at increased risk of death and adverse clinical events. Serum ferritin concentration is a marker of varied pathophysiological events and is elevated with increased liver iron concentration, hepatic necroinflammation, and systemic illness, all of which may cause a deterioration in liver function and clinical status. The aim of this study was to determine whether serum ferritin concentration is an independent prognostic factor in subjects awaiting OLT...
May 2010: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/19745756/survival-in-asian-americans-after-treatments-for-hepatocellular-carcinoma-a-seven-year-experience-at-ucla
#3
Myron J Tong, Disaya Chavalitdhamrong, David S K Lu, Steven S Raman, Antoinette Gomes, John P Duffy, Johnny C Hong, Ronald W Busuttil
BACKGROUND/RATIONALE: Hepatocellular carcinoma (HCC) is a common malignancy in Asians and is related to the high incidence of chronic viral hepatitis in this ethnic population. The aims of this study were to examine the tumor characteristics and liver disease status in HCC patients of Asian ancestry and determine their survival after treatments for HCC. RESULTS: Between September 2000 and December 2007, 278 patients, mean age 61.5 years, presented with HCC to the University of California Los Angeles (UCLA) Liver Cancer Center...
March 2010: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/18637468/a-quarter-century-of-liver-transplantation-at-ucla
#4
REVIEW
John P Duffy, Douglas G Farmer, Ronald W Busuttil
Orthotopic liver transplant (OLT) has become the best and most durable treatment for end stage liver disease (ESLD) of any etiology. The UCLA program, established in 1984, has accumulated one of the world's most extensive experiences with this procedure. The UCLA experience has been built on the classical techniques of Starzl, yet has forged innovations such as split liver transplantation and use of extended criteria donor organs. The UCLA program also reports one of the largest experiences in pediatric liver transplantation and has demonstrated that recipient renal function is a main predictor of post-transplant survival...
2007: Clinical Transplants
https://www.readbyqxmd.com/read/17717454/liver-transplantation-criteria-for-hepatocellular-carcinoma-should-be-expanded-a-22-year-experience-with-467-patients-at-ucla
#5
John P Duffy, Andrew Vardanian, Elizabeth Benjamin, Melissa Watson, Douglas G Farmer, Rafik M Ghobrial, Gerald Lipshutz, Hasan Yersiz, David S K Lu, Charles Lassman, Myron J Tong, Jonathan R Hiatt, Ronald W Busuttil
OBJECTIVE: To assess the efficacy of orthotopic liver transplantation (OLT) for hepatocellular carcinoma (HCC) and the impact of current staging criteria on long term survival. SUMMARY BACKGROUND DATA: HCC is becoming an increasingly common indication for OLT. Medicare approves OLT only for HCCs meeting the Milan criteria, thus limiting OLT for an expanding pool of potential liver recipients. We analyzed our experience with OLT for HCC to determine if expansion of criteria for OLT for HCC is warranted...
September 2007: Annals of Surgery
https://www.readbyqxmd.com/read/16989581/the-status-of-liver-transplantation-for-hepatitis-c
#6
REVIEW
Andrew M Cameron, Ronald W Busuttil
The hepatitis C virus (HCV) infects 3% of the world's population, or approximately 170 million people. Most of those acutely infected progress to chronic infection and are unresponsive to existing antiviral treatment. Over a 20-year period, chronic HCV infection leads to cirrhosis and the sequelae of end-stage liver disease, including hepatic encephalopathy, ascites, variceal haemorrhage and hepatocellular carcinoma. Orthotopic liver transplantation (OLT) is the optimal treatment for decompensated HCV cirrhosis, but is limited by organ availability and universal graft reinfection...
October 2006: Expert Opinion on Biological Therapy
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