Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
REVIEW
A M Winters, J Bakker, J Ten Hoor, H J G Bilo, P F Roodbol, M A Edens, E J Finnema
PURPOSE: It is unclear whether the Geriatric-8 (G8) has the accuracy to preselect patients for complete geriatric assessment, and has the ability to predict adverse outcomes in patients with colorectal cancer (CRC). We therefore aimed to determine whether the G8, or other variables present in the medical record, are applicable in predicting 30-day adverse outcomes in older patients undergoing surgery for CRC. METHODS: We performed a retrospective cohort study involving patients ≥70 years who had surgery for CRC between 2018 and 2020 in a general hospital in the Netherlands...
April 16, 2024: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
#2
REVIEW
Lourdes M DelRosso, Daniel L Picchietti, Denise Sharon, Karen Spruyt, Judith A Owens, Arthur S Walters, Marco Zucconi, Raffaele Ferri
This systematic review evaluates the scientific literature on pediatric periodic limb movement disorder (PLMD), adhering to PRISMA guidelines and utilizing PICOS criteria. The search across PubMed, EMBASE, and Scopus yielded 331 articles, with 17 meeting inclusion criteria. Diagnostic criteria evolved, with polysomnography and PLMS index ≥5 required since 2003. Also, PLMD diagnosis mandates clinical consequences like insomnia, hypersomnia, and fatigue, excluding comorbidities causing sleep disruption...
April 16, 2024: Sleep Medicine Reviews
#3
JOURNAL ARTICLE
Seçil Ekiz Erim, Havva Sert
OBJECTIVES: The study aimed to investigate the effect of the circadian timing program (SİZAP) developed for evening-chronotype individuals with obesity on obesity management and sleep quality. METHODS: This single-site, randomized controlled trial with an experimental research design was registered in ClinicalTrials.gov. It was reported in accordance with the "Consolidated Standards of Reporting Trials" (CONSORT) randomized controlled trial guidelines. The study sample consisted of 38 evening-chronotype individuals with first-degree obesity, with 19 individuals in each study group...
April 16, 2024: Sleep Medicine
#4
JOURNAL ARTICLE
Stefanie N Hakkesteegt, Isabel C Jongen, Caroline A Hundepool, Mark J W van der Oest, Liron S Duraku, Reinier Feitz, J Michiel Zuidam
BACKGROUND: Surgical management of midcarpal instability (MCI), also referred to as carpal instability nondissociative, remains controversial due to limited evidence on different techniques. This study aimed to assess and compare differences in patient-reported pain, hand and wrist function, patient satisfaction, range of motion, and return to work in patients with non-traumatic MCI who underwent surgical treatment either through dorsal wrist capsulodesis or three-ligament tenodesis (3LT)...
April 23, 2024: Plastic and Reconstructive Surgery
#5
J X Chen, B B Song, S Q Gao, M M Pan, H N Huang, D B Wang, H Y Peng, Y Z Wang
No abstract text is available yet for this article.
April 23, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
#6
JOURNAL ARTICLE
Nathan N O'Hara, Mark J Gage, Casey Loudermilk, Carolyn Drogt, Niek S Klazinga, Dionne S Kringos, Lily R Mundy
INTRODUCTION: Financial toxicity is highly prevalent in patients after an orthopaedic injury. However, little is known regarding the conditions that promote and protect against this financial distress. Our objective was to understand the factors that cause and protect against financial toxicity after a lower extremity fracture. METHODS: A qualitative study was conducted using semi-structured interviews with 20 patients 3 months after surgical treatment of a lower extremity fracture...
April 17, 2024: Journal of the American Academy of Orthopaedic Surgeons
#7
JOURNAL ARTICLE
Risa Kagan, James A Simon, Steven R Goldstein, Barry S Komm, Simon N Jenkins, David J Portman
OBJECTIVE: The aim of this study was to demonstrate whether lasofoxifene improves vaginal signs/symptoms of genitourinary syndrome of menopause. METHODS: Two identical, phase 3 trials randomized postmenopausal women with moderate to severe vaginal symptoms to oral lasofoxifene 0.25 or 0.5 mg/d, or placebo, for 12 week. Changes from baseline to week 12 in most bothersome symptom, vaginal pH, and percentages of vaginal parabasal and superficial cells were evaluated...
April 23, 2024: Menopause: the Journal of the North American Menopause Society
#8
JOURNAL ARTICLE
Pengcheng Yu, Haochang Zhang, Fiaz Hussain, Jing Luo, Wen Tang, Jiuwei Lei, Lei Gao, Denys Butenko, Changhong Wang, Jinlong Zhu, Wen Yin, Hao Zhang, Songbai Han, Ruqiang Zou, Wei Chen, Yusheng Zhao, Wei Xia, Xueliang Sun
Lithium (Li) metal solid-state batteries feature high energy density and improved safety and thus are recognized as promising alternatives to traditional Li-ion batteries. In practice, using Li metal anodes remains challenging because of the lack of a superionic solid electrolyte that has good stability against reduction decomposition at the anode side. Here, we propose a new electrolyte design with an antistructure (compared to conventional inorganic structures) to achieve intrinsic thermodynamic stability with a Li metal anode...
April 23, 2024: Journal of the American Chemical Society
#9
JOURNAL ARTICLE
Zacchaeus S Ololade, Olayinka F Onifade, John C Eze, Olawumi T Oyebanji, Anikeola C Olaniran, Iyaduni A Anuoluwa, Oluwatope O Idowu, Bessie E Tommy
This study was aimed at investigating the ability of extract of Annona muricata (AM) flower-petals in ameliorating the toxic effects of acetaminophen on the kidneys of albino rats. The biochemical results showed a marked increase in AM 200 mg (32.84 ± 0.14) and AM 400 mg (32.64 ± 0.78). Increase levels of total protein in AM 200 mg (77.00 ± 5.65) displays nephroprotective potential of the flower extract. Reduction of renal activities of serum urea in AM 400 mg group (6...
April 23, 2024: Natural Product Research
#10
JOURNAL ARTICLE
Lihong Wang-Bishop, Mohamed Wehbe, Lucinda E Pastora, Jinming Yang, Blaise R Kimmel, Kyle M Garland, Kyle W Becker, Carcia S Carson, Eric W Roth, Katherine N Gibson-Corley, David Ulkoski, Venkata Krishnamurthy, Olga Fedorova, Ann Richmond, Anna Marie Pyle, John T Wilson
Pharmacological activation of the retinoic acid-inducible gene I (RIG-I) pathway holds promise for increasing tumor immunogenicity and improving the response to immune checkpoint inhibitors (ICIs). However, the potency and clinical efficacy of 5'-triphosphate RNA (3pRNA) agonists of RIG-I are hindered by multiple pharmacological barriers, including poor pharmacokinetics, nuclease degradation, and inefficient delivery to the cytosol where RIG-I is localized. Here, we address these challenges through the design and evaluation of ionizable lipid nanoparticles (LNPs) for the delivery of 3p-modified stem-loop RNAs (SLRs)...
April 23, 2024: ACS Nano
#11
JOURNAL ARTICLE
Claire Cordella, Lauren Di Filippo, Vijaya B Kolachalama, Swathi Kiran
PURPOSE: Speech fluency has important diagnostic implications for individuals with poststroke aphasia (PSA) as well as primary progressive aphasia (PPA), and quantitative assessment of connected speech has emerged as a widely used approach across both etiologies. The purpose of this review was to provide a clearer picture on the range, nature, and utility of individual quantitative speech/language measures and methods used to assess connected speech fluency in PSA and PPA, and to compare approaches across etiologies...
April 23, 2024: American Journal of Speech-language Pathology
#12
JOURNAL ARTICLE
Alessandra Canetta, Serhii Volosheniuk, Sayooj Satheesh, José Pedro Alvarinhas Batista, Aloïs Castellano, Riccardo Conte, Daniel George Chica, Kenji Watanabe, Takashi Taniguchi, Xavier Roy, Herre S J van der Zant, Marko Burghard, Matthieu Jean Verstraete, Pascal Gehring
Heat-to-charge conversion efficiency of thermoelectric materials is closely linked to the entropy per charge carrier. Thus, magnetic materials are promising building blocks for highly efficient energy harvesters as their carrier entropy is boosted by a spin degree of freedom. In this work, we investigate how this spin-entropy impacts heat-to-charge conversion in the A-type antiferromagnet CrSBr. We perform simultaneous measurements of electrical conductance and thermocurrent while changing magnetic order using the temperature and magnetic field as tuning parameters...
April 23, 2024: Nano Letters
#13
JOURNAL ARTICLE
Lauren Griffin, Mark Richard Stephen Garren, Patrick Maffe, Sama Ghalei, Elizabeth J Brisbois, Hitesh Handa
Of the 27 million surgeries performed in the United States each year, a reported 2.6% result in a surgical site infection (SSI), and Staphylococci species are commonly the culprit. Alternative therapies, such as nitric oxide (NO)-releasing biomaterials, are being developed to address this issue. NO is a potent antimicrobial agent with several modes of action, including oxidative and nitrosative damage, disruption of bacterial membranes, and dispersion of biofilms. For targeted antibacterial effects, NO is delivered by exogenous donor molecules, like S -nitroso- N -acetylpenicillamine (SNAP)...
April 23, 2024: ACS Applied Bio Materials
#14
JOURNAL ARTICLE
Ahmed Siddiqi, Ignacio Pasqualini, Joshua Tidd, Pedro J Rullán, Alison K Klika, Trevor G Murray, Joshua K Johnson, Nicolas S Piuzzi
The Centers for Medicare & Medicaid Services is continually working to mitigate unnecessary expenditures, particularly in post-acute care (PAC). Medicare reimburses for orthopaedic surgeon services in varied models, including fee-for-service, bundled payments, and merit-based incentive payment systems. The goal of these models is to improve the quality of care, reduce health-care costs, and encourage providers to adopt innovative and efficient health-care practices. This article delves into the implications of each payment model for the field of orthopaedic surgery, highlighting their unique features, incentives, and potential impact in the PAC setting...
April 23, 2024: Journal of Bone and Joint Surgery. American Volume
#15
REVIEW
Grigory Ostrovskiy, Alexandra S Reynolds, Aarti Sarwal
Acute stroke is one of the most common neurologic emergencies encountered by emergency clinicians. While point of care ultrasound has been a core part of emergency clinicians' training and practice for many years, the use of specialized ultrasound modalities in the care of acute ischemic stroke has not been as widely adopted. This review discusses the use of ultrasound in acute stroke, with a focus on applications of interest to emergency clinicians. Transcranial Doppler, carotid Doppler, microembolic signal detection, transthoracic echocardiography, evaluation for collateral circulation and optic nerve sheath diameter measurement are discussed in a case-based format, with a focus on practical applications for emergency clinicians...
April 25, 2024: Emergency Medicine Practice
#16
JOURNAL ARTICLE
Yu Jiang, Zhou Wan, Qi Liu, Xinxin Li, Bo Jiang, Mudan Guo, Pengjue Fan, Siyi Du, Doudou Xu, Chen Liu
Titanium (Ti) implants are widely used in orthopedic and dental applications due to their excellent biocompatibility and mechanical properties. However, bacterial adhesion and subsequent biofilm formation on implant surfaces pose a significant risk of postoperative infections and complications. Conventional surface modifications often lack long-lasting antibacterial efficacy, necessitating the development of novel coatings with enhanced antimicrobial properties. This study aims to develop a novel Ag-TiO2 -OTS (Silver-Titanium dioxide-Octadecyltrichlorosilane, ATO) nanocomposite coating, through a chemical plating method...
April 23, 2024: Journal of Biomaterials Science. Polymer Edition
#17
JOURNAL ARTICLE
Sushant Sharma Chaudhary, Andrew Toivonen, Gaurav Waratkar, Geoffrey Mo, Deep Chatterjee, Sarah Antier, Patrick Brockill, Michael W Coughlin, Reed Essick, Shaon Ghosh, Soichiro Morisaki, Pratyusava Baral, Amanda Baylor, Naresh Adhikari, Patrick Brady, Gareth Cabourn Davies, Tito Dal Canton, Marco Cavaglia, Jolien Creighton, Sunil Choudhary, Yu-Kuang Chu, Patrick Clearwater, Luke Davis, Thomas Dent, Marco Drago, Becca Ewing, Patrick Godwin, Weichangfeng Guo, Chad Hanna, Rachael Huxford, Ian Harry, Erik Katsavounidis, Manoj Kovalam, Alvin K Y Li, Ryan Magee, Ethan Marx, Duncan Meacher, Cody Messick, Xan Morice-Atkinson, Alexander Pace, Roberto De Pietri, Brandon Piotrzkowski, Soumen Roy, Surabhi Sachdev, Leo P Singer, Divya Singh, Marek Szczepanczyk, Daniel Tang, Max Trevor, Leo Tsukada, Verónica Villa-Ortega, Linqing Wen, Daniel Wysocki
Multimessenger searches for binary neutron star (BNS) and neutron star-black hole (NSBH) mergers are currently one of the most exciting areas of astronomy. The search for joint electromagnetic and neutrino counterparts to gravitational wave (GW)s has resumed with ALIGO's, AdVirgo's and KAGRA's fourth observing run (O4). To support this effort, public semiautomated data products are sent in near real-time and include localization and source properties to guide complementary observations. In preparation for O4, we have conducted a study using a simulated population of compact binaries and a mock data challenge (MDC) in the form of a real-time replay to optimize and profile the software infrastructure and scientific deliverables...
April 30, 2024: Proceedings of the National Academy of Sciences of the United States of America
#18
JOURNAL ARTICLE
Daniela Rojo, Clara E Hael, Agustina Soria, Flávio S J de Souza, Malcolm J Low, Lucía F Franchini, Marcelo Rubinstein
Food intake and energy balance are tightly regulated by a group of hypothalamic arcuate neurons expressing the proopiomelanocortin ( POMC) gene. In mammals, arcuate-specific POMC expression is driven by two cis -acting transcriptional enhancers known as nPE1 and nPE2. Because mutant mice lacking these two enhancers still showed hypothalamic Pomc mRNA, we searched for additional elements contributing to arcuate Pomc expression. By combining molecular evolution with reporter gene expression in transgenic zebrafish and mice, here, we identified a mammalian arcuate-specific Pomc enhancer that we named nPE3, carrying several binding sites also present in nPE1 and nPE2 for transcription factors known to activate neuronal Pomc expression, such as ISL1, NKX2...
April 30, 2024: Proceedings of the National Academy of Sciences of the United States of America
#19
JOURNAL ARTICLE
Wei-Hsin Hsu, Kai-Wen Cheng, Tzu-Hsuan Feng, Ju-Yu Chen, Guan-Yuan Chen, Lian-Yu Chen, Te I Weng, Cheng-Chih Hsu
Drug abuse is a severe social problem worldwide. Particularly, the issue of new psychoactive substances (NPSs) have increasingly emerged. NPSs are structural or functional analogs of traditional illicit drugs, such as cocaine, cannabis, and amphetamine; these molecules provide the same or more severe neurological effects. Usually, immunoassays are utilized in the preliminary screening method. However, NPSs have poor detectability in commercially available immunoassay kits. Meanwhile, various chromatography combined with the mass spectrometry platform have been developed to quantify NPSs...
April 23, 2024: Journal of the American Society for Mass Spectrometry
#20
JOURNAL ARTICLE
Jacqueline W Miller, Jessica A King, Katrina F Trivers, Machell Town, Susan A Sabatino, Mary Puckett, Lisa C Richardson
INTRODUCTION: Approximately 40,000 U.S. women die from breast cancer each year. Mammography is recommended to screen for breast cancer and reduce breast cancer mortality. Adverse social determinants of heath (SDOH) and health-related social needs (HRSNs) (e.g., lack of transportation and social isolation) can be barriers to getting mammograms. METHODS: Data from the 2022 Behavioral Risk Factor Surveillance System were analyzed to estimate the prevalence of mammography use within the previous 2 years among women aged 40-74 years by jurisdiction, age group, and sociodemographic factors...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
