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https://www.readbyqxmd.com/read/29664900/accuracy-and-precision-of-scvo2-measured-with-the-cevox-device-a-prospective-study-in-patients-with-a-wide-variation-of-scvo2-values
#1
Alexander Herner, Bernhard Haller, Ulrich Mayr, Sebastian Rasch, Lea Offman, Roland Schmid, Wolfgang Huber
INTRODUCTION: Central-venous oxygen saturation (ScvO2) is a key parameter of hemodynamic monitoring and has been suggested as therapeutic goal for resuscitation. Several devices offer continuous monitoring features. The CeVOX-device (Pulsion Medical Systems) uses a fibre-optic probe inserted through a conventional central-venous catheter (CVC) to obtain continuous ScvO2. OBJECTIVES: Since there is a lack of studies validating the CeVOX, we prospectively analyzed data from 24 patients with CeVOX-monitoring...
2018: PloS One
https://www.readbyqxmd.com/read/29659198/in-silico-modeling-of-oxygen-enhanced-mri-of-specific-ventilation
#2
Wendy Kang, Merryn H Tawhai, Alys R Clark, Rui C Sá, Eric T Geier, G Kim Prisk, Kelly S Burrowes
Specific ventilation imaging (SVI) proposes that using oxygen-enhanced 1H MRI to capture signal change as subjects alternatively breathe room air and 100% O2 provides an estimate of specific ventilation distribution in the lung. How well this technique measures SV and the effect of currently adopted approaches of the technique on resulting SV measurement is open for further exploration. We investigated (1) How well does imaging a single sagittal lung slice represent whole lung SV? (2) What is the influence of pulmonary venous blood on the measured MRI signal and resultant SVI measure? and (3) How does inclusion of misaligned images affect SVI measurement? In this study, we utilized two patient-based in silico models of ventilation, perfusion, and gas exchange to address these questions for normal healthy lungs...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29649820/accuracy-of-acid-base-diagnoses-using-the-central-venous-blood-gas-in-the-medical-intensive-care-unit
#3
Sarah J Schrauben, Dan Negoianu, Cristiana Costa, Raphael M Cohen, Stanley Goldfarb, Barry D Fuchs, Jeffrey S Berns
BACKGROUND: Acid-base disturbances are frequent in critically ill patients. Arterial blood gas (ABG) is the gold standard in the diagnosis of these disturbances, but it is invasive with potential hazards. For patients with a central venous catheter, venous blood gas (VBG) sampling may be an alternative, less-invasive diagnostic tool. However, the accuracy of a central VBG-based acid-base disorder diagnosis compared to an ABG is unknown. The primary objective of this study was to assess the accuracy of a central VBG-based acid-base disorder diagnosis compared to the "gold standard" ABG in critically ill patients...
April 12, 2018: Nephron
https://www.readbyqxmd.com/read/29615382/severe-heinz-body-anemia-and-methemoglobinemia-in-a-kitten-with-chronic-diarrhea
#4
P Cavana, E Irato, B Miniscalco, P Gianella
A 2-month-old kitten was referred for depression and partial anorexia since 3 days and chronic diarrhea lasting for over 3 weeks. General physical examination showed pale and cyanotic mucous membranes. Blood sample was of brownish appearance. Venous blood gas analysis and complete blood count showed 16% methemoglobin level and severe regenerative anemia with Heinz bodies in about 40% of the erythrocytes, respectively. The kitten was transfused with fresh whole blood and treated with supportive care, antimicrobial and antioxidant agents...
April 2018: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29614572/-four-cases-of-acute-respiratory-distress-syndrome-patients-transported-with-veno-venous-extracorporeal-membrane-oxygenation
#5
Z Zhao, X Y Hong, Y Y Liu, X J Zhang, L S Bao, H T Gao, X H Liu, Z C Feng
Objective: To retrospectively review 4 cases diagnosed with pediatric acute respiratory distress syndrome (ARDS) who were transported with veno-venous (V-V) extracorporeal membrane oxygenation (ECMO) from April 2016 to March 2017. Methods: Four patients were transported to Bayi Children's Hospital Afflicted to the PLA Army General Hospital, with V-V ECMO. Their vital signs, blood-gas analysis and chest X-ray before and after transportation were compared. The length of ECMO, pediatric intensive care unit (PICU) stay and hospitalization, and the prognosis were analyzed...
April 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29602665/relocation-of-blood-gas-laboratory-to-the-emergency-department-helps-decrease-lactic-acid-values
#6
Jared Brazg, Phyllis Huang, Corey Weiner, Guneet Singh, Antonios Likourezos, Linda Salem, Eitan Dickman, John Marshall
IMPORTANCE: Emergency physicians often rely on Lactic Acid (LA) values to make important clinical decisions. Accuracy of LA values improve when blood gas analysis is performed in the emergency department (ED) as opposed to a satellite laboratory (SL). OBJECTIVE: To investigate an association between blood gas laboratory location and accuracy of ED lactic acid samples. METHODS: The study team evaluated lactic acid values from venous and arterial blood gas samples drawn between June 1, 2015 and September 30, 2016...
March 20, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29582442/relationship-between-fetal-peak-systolic-velocity-in-middle-cerebral-artery-and-umbilical-blood-gas-values-and-hemoglobin-levels-in-diabetic-pregnant-women
#7
Mehmet S Kutuk, Mehmet Dolanbay, Ayse F Gokmen Karasu, Mahmut T Ozgun
PURPOSE: To assess the relationship between peak systolic velocity in the middle cerebral artery (MCA-PSV) and fetal hypoxia in diabetic pregnant women requiring insulin therapy. METHODS: The data of diabetic pregnant women using insulin who were followed in our departments were reviewed retrospectively. The relationships between MCA-PSV and umbilical cord pO2, pCO2, base deficit, hemoglobin, and birth weight were analyzed. RESULTS: A total of 120 cases were included in the final analysis...
March 26, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29559357/relocation-of-blood-gas-laboratory-to-the-emergency-department-helps-decrease-lactic-acid-values
#8
Jared Brazg, Phyllis Huang, Corey Weiner, Guneet Singh, Antonios Likourezos, Linda Salem, Eitan Dickman, John Marshall
IMPORTANCE: Emergency Physicians often rely on Lactic Acid (LA) values to make important clinical decisions. Accuracy of LA values improve when blood gas analysis is performed in the emergency department (ED) as opposed to a satellite laboratory (SL). OBJECTIVE: To investigate an association between blood gas laboratory location and accuracy of ED lactic acid samples. METHODS: The study team evaluated lactic acid values from venous and arterial blood gas samples drawn between June 1, 2015 and September 30, 2016...
March 12, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29537404/going-beyond-audit-and-feedback-towards-behaviour-based-interventions-to-change-physician-laboratory-test-ordering-behaviour
#9
Z Meidani, G A Mousavi, D Kheirkhah, N Benar, M R Maleki, M Sharifi, A Farrokhian
Studies indicate there are a variety of contributing factors affecting physician test ordering behaviour. Identifying these behaviours allows development of behaviour-based interventions. Methods Through a pilot study, the list of contributing factors in laboratory tests ordering, and the most ordered tests, were identified, and given to 50 medical students, interns, residents and paediatricians in questionnaire form. The results showed routine tests and peer or supervisor pressure as the most influential factors affecting physician ordering behaviour...
December 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29519760/emergency-medical-technician-performed-point-of-care-blood-analysis-using-the-capillary-blood-obtained-from-skin-puncture
#10
Changsun Kim, Hansol Kim
OBJECTIVE: Comparing a point-of-care (POC) test using the capillary blood obtained from skin puncture with conventional laboratory tests. METHODS: In this study, which was conducted at the emergency department of a tertiary care hospital in April-July 2017, 232 patients were enrolled, and three types of blood samples (capillary blood from skin puncture, arterial and venous blood from blood vessel puncture) were simultaneously collected. Each blood sample was analyzed using a POC analyzer (epoc® system, USA), an arterial blood gas analyzer (pHOx®Ultra, Nova biomedical, USA) and venous blood analyzers (AU5800, DxH2401, Beckman Coulter, USA)...
December 9, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29515463/pulmonary-circulation-transvascular-fluid-fluxes-do-not-change-during-general-anesthesia-in-dogs
#11
Olga Frlic, Alenka Seliškar, Aleksandra Domanjko Petrič, Rok Blagus, George Heigenhauser, Modest Vengust
General anesthesia (GA) can cause abnormal lung fluid redistribution. Pulmonary circulation transvascular fluid fluxes ( J VA ) are attributed to changes in hydrostatic forces and erythrocyte volume (EV) regulation. Despite the very low hydraulic conductance of pulmonary microvasculature it is possible that GA may affect hydrostatic forces through changes in pulmonary vascular resistance (PVR), and EV through alteration of erythrocyte transmembrane ion fluxes ( ion J VA ). Furosemide (Fur) was also used because of its potential to affect pulmonary hydrostatic forces and ion J VA ...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29514541/assessing-acid-base-status-in-circulatory-failure-relationship-between-arterial-and-peripheral-venous-blood-gas-measurements-in-hypovolemic-shock
#12
Scott E Rudkin, Craig L Anderson, Tristan R Grogan, David A Elashoff, Richard M Treger
BACKGROUND AND OBJECTIVES: In severe circulatory failure agreement between arterial and mixed venous or central venous values is poor; venous values are more reflective of tissue acid-base imbalance. No prior study has examined the relationship between peripheral venous blood gas (VBG) values and arterial blood gas (ABG) values in hemodynamic compromise. The objective of this study was to examine the correlation between hemodynamic parameters, specifically systolic blood pressure (SBP) and the arterial-peripheral venous (A-PV) difference for all commonly used acid-base parameters (pH, Pco2 , and bicarbonate)...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29509139/determination-of-reference-intervals-and-comparison-of-venous-blood-gas-parameters-using-a-standard-and-nonstandard-collection-method-in-51-dogs
#13
K Bachmann, A Kutter, R S Jud Schefer, N Sigrist
The aim of this study was to determine reference intervals (RI) for venous blood parameters determined with the RAPIDPoint 500 (RP500) blood gas analyzer using blood gas syringes (BGS) and to determine whether immediate analysis of venous blood collected into lithium heparin (LH) tubes can replace anaerobic blood sampling into BGS. The null hypothesis was that canine venous blood samples collected in BGS and in LH tubes are comparable. Jugular blood was collected from 51 healthy dogs into a BGS and a LH tube...
March 2018: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29480748/precise-control-of-target-temperature-using-n-6-cyclohexyladenosine-and-real-time-control-of-surface-temperature
#14
Bernard W Laughlin, Isaac R Bailey, Sarah A Rice, Zeinab Barati, Lori K Bogren, Kelly L Drew
Targeted temperature management is standard of care for cardiac arrest and is in clinical trials for stroke. N6 -cyclohexyladenosine (CHA), an A1 adenosine receptor agonist, inhibits thermogenesis and induces onset of hibernation in hibernating species. Despite promising thermolytic efficacy of CHA, prior work has failed to achieve and maintain a prescribed target core body temperature (Tb ) between 32°C and 34°C for 24 hours. We instrumented Sprague-Dawley rats (n = 19) with indwelling arterial and venous cannulae and a transmitter for monitoring Tb and ECG, then administered CHA via continuous IV infusion or intraperitoneal (IP) injection...
February 26, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29444699/the-hyster-study-the-effect-of-intracervically-administered-terlipressin-versus-placebo-on-the-number-of-gaseous-emboli-and-fluid-intravasation-during-hysteroscopic-surgery-study-protocol-for-a-randomized-controlled-clinical-trial
#15
Lucilla E Overdijk, Bart M P Rademaker, Paul J M van Kesteren, Peter de Haan, Robert K Riezebos, Oscar C H Haude
BACKGROUND: Transcervical resection of myoma or endometrium is a safe, hysteroscopic, minimally invasive procedure. However, intravasation of distension fluid is a common phenomenon during these procedures. In a previous study we observed venous gas emboli in almost every patient. The severity of hysteroscopic-derived embolization has been shown to be correlated to the amount of intravasation. In addition, paradoxical gas embolism, which is potentially dangerous, was observed in several patients...
February 14, 2018: Trials
https://www.readbyqxmd.com/read/29434789/effects-of-pumpless-extracorporeal-lung-assist-on-hemodynamics-gas-exchange-and-inflammatory-cascade-response-during-experimental-lung-injury
#16
Zhihai Ju, Jinhui Ma, Chen Wang, Jie Yu, Yeru Qiao, Feilong Hei
Pumpless extracorporeal lung assist (pECLA) has been reported to efficiently remove the systemic CO 2 production and provide mild to moderate oxygenation, thereby allowing for ventilator settings and modes prioritizing oxygenation and lung protection. However, an adequate bypass flow, the capacity to provide respiratory support and the effect on the inflammatory cascade response and tissue perfusion require further study to be determined. After induction of acute lung injury (ALI) by oleic acid injection, pECLA was implemented in 12 anaesthetized and mechanically ventilated dogs for 48 h...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29425776/the-effects-of-hemoglobin-glutamer-200-and-ino-on-pulmonary-vascular-tone-and-arterial-oxygenation-in-an-experimental-acute-respiratory-distress-syndrome
#17
Maria Theresa Voelker, Andreas Bergmann, Thilo Busch, Nora Jahn, Sven Laudi, Katharina Noreikat, Philipp Simon, Sven Bercker
INTRODUCTION: Hemoglobin-based oxygen carriers (HBOC) have been developed as an alternative to blood transfusions. Their nitric-oxide-scavenging properties HBOC also induce vasoconstriction. In acute lung injury, an excess of nitric oxide results in a general vasodilation, reducing oxygenation by impairing the hypoxic pulmonary vasoconstriction. Inhaled nitric oxide (iNO) is used to correct the ventilation perfusion mismatch. We hypothesized that the additional use of HBOC might increase this effect...
February 6, 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29423508/association-of-retinopathy-of-prematurity-with-low-levels-of-arachidonic-acid-a-secondary-analysis-of-a-randomized-clinical-trial
#18
Chatarina A Löfqvist, Svetlana Najm, Gunnel Hellgren, Eva Engström, Karin Sävman, Anders K Nilsson, Mats X Andersson, Anna-Lena Hård, Lois E H Smith, Ann Hellström
Importance: Mice with oxygen-induced retinopathy fed matched diets except for ω-3 long-chain polyunsaturated fatty acids (LC-PUFAs) vs ω-6 LC-PUFAs demonstrate relative antiangiogenic and neuroprotective associations of ω-3 LC-PUFAs. However, supplementing preterm infants with LC-PUFAs has been inconsistent in reducing major preterm morbidities. However, few studies measured serum lipid levels after supplementation. Objective: To examine the associated risk of retinopathy of prematurity (ROP) from the levels of circulating ω-3 and ω-6 LC-PUFAs...
March 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29404891/assessment-of-changes-in-blood-glucose-concentration-with-intravascular-microdialysis
#19
Marc-Olivier Fischer, Corentin Gouëzel, Sabine Fradin, Vladimir Saplacan, Jean-Louis Gérard, Jean-Luc Fellahi, Jean-Luc Hanouz
Blood glucose and its variability of is a major prognostic factor associated with morbidity. We hypothesized that intravenous microdialysis incorporated in a central venous catheter (CVC) would be interchangeable with changes in blood glucose measured by the reference method using a blood gas analyzer. Microdialysis and central venous blood glucose measurements were simultaneously recorded in high-risk cardiac surgical patients. The correlation between absolute values was determined by linear regression and the Bland-Altman test for repeated measurements was used to compare bias, precision, and limits of agreement...
February 5, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29397598/-the-clinical-significance-of-microcirculation-and-oxygen-metabolism-evaluation-in-acute-kidney-injury-assessment-in-patients-with-septic-shock-after-resuscitation
#20
C Yu, D W Liu, X T Wang, H W He, P Pan, Z Q Xing
Objective: To evaluate the value of microcirculation and oxygen metabolism evaluation (MicrOME) in acute kidney injury(AKI) evaluation in patients with septic shock after resuscitation. Methods: Consecutive patients with septic shock after resuscitation and mechanical ventilation were enrolled from October 2016 to February 2017 in ICU at Peking Union Medical College Hospital.Patients were divided into 3 groups based on 10 min transcutaneous oxygen challenge test transcutaneous partial pressure of oxygen(PtcO(2))and venoarterial pressure of carbon dioxide difference (Pv-aCO(2)) /arteriovenous O(2) content difference (Ca-vO(2)) by blood gas analysis, i...
February 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
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