keyword
MENU ▼
Read by QxMD icon Read
search

tH

keyword
https://www.readbyqxmd.com/read/29774756/28-th-meeting-of-the-european-association-for-the-study-of-diabetes-eye-complications-study-group-easdec-belfast-northern-ireland-24-th-26-th-may-2018
#1
(no author information available yet)
No abstract text is available yet for this article.
May 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29774314/surgical-highlights-from-the-40-th-san-antonio-breast-cancer-symposium-5-9-december-2017-san-antonio-texas
#2
Enver Özkurt
This year San Antonio Breast Cancer Symposium (SABCS) celebrated its 40th anniversary. As in the past years, this year's conference was held in Henry B. Gonzalez Convention Centre, San Antonio, Texas, on 5-9 December 2017. The conference highlighted many different topic on breast cancer including basic science, translational research, local therapies, systemic therapies, survivorship, early clinical trials, and surgical topics. Even though SABCS evolved towards basic science and systemic therapy based manner in recent years, there were some important topics about local therapies and surgical approach...
April 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29774313/echoes-from-the-40-th-annual-san-antonio-breast-cancer-symposium-2017
#3
Bekir Kuru
The Annual San Antonio Symposium was held on 5-9, December, 2017 in San Antonio, Texas, USA (1). As expected, many new studies were presented for the first time at the sessions. The unofficial opening lecture in my point of view was given on locoregional recurrence by Monica Morrow from MSKCC, New York. As always, Morrow's lecture on "Challenges in the surgical management of locoregional recurrence" attracted great interest. The other prominent conferences were given on "Individualizing Management of the Axillary Nodes" by Tari A...
April 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29773890/intraperitoneal-administration-of-the-anti-il-23-antibody-prevents-the-establishment-of-intestinal-nematodes-in-mice
#4
M Gomez-Samblas, D Bernal, A Bolado-Ortiz, S Vilchez, F Bolás-Fernández, A M Espino, M Trelis, A Osuna
Previous studies have established that an increased Th-9 response creates a hostile environment for nematode parasites. Given that IL-23, a cytokine required for maintenance of the IL-17-secreting phenotype, has inhibitory effects on IL-9 production, we hypothesized that reducing circulating IL-23 by treatment with anti-IL-23 antibodies would reduce the establishment and development of parasitic intestinal nematodes. In this study, we show that animals treated with anti-IL-23 monoclonal antibodies showed a drastic reduction in the number of mouse pinworms (Aspiculuris tetraptera) recovered from the intestine (p < 0...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29773854/genome-wide-haplotype-association-analysis-of-primary-biliary-cholangitis-risk-in-japanese
#5
Cindy Im, Yadav Sapkota, Wonjong Moon, Minae Kawashima, Minoru Nakamura, Katsushi Tokunaga, Yutaka Yasui
Primary biliary cholangitis (PBC) susceptibility loci have largely been discovered through single SNP association testing. In this study, we report genic haplotype patterns associated with PBC risk genome-wide in two Japanese cohorts. Among the 74 genic PBC risk haplotype candidates we detected with a novel methodological approach in a discovery cohort of 1,937 Japanese, nearly two-thirds were replicated (49 haplotypes, Bonferroni-corrected P < 6.8 × 10-4 ) in an independent Japanese cohort (N = 949)...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29772555/deiodinases-share-an-evolutionarily-conserved-thyroid-hormone-binding-motif
#6
Salvatore Benvenga, Fabrizio Guarneri
Human and animal thyroid hormone (TH) plasma carriers (THPC, n=426), cell surface TH transporters (CSTT, n=8,691), and TH nuclear receptors (TR, n=624) share a 49-position long TH-binding motif. Particularly conserved are positions 22-26, where a 5-residue TH-binding motif was originally detected. We extended our research to the 488 sequences of human and animal selenodeiodinases (dio-1, dio-2, dio-3).  In the 10,229 sequences (THPC+CSTT+TR+deiodinases), 15/49 positions are very highly and another 18/49 highly conserved...
June 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/29770827/%C3%AF-%C3%AF-stacking-induced-high-current-density-and-improved-efficiency-in-ternary-organic-solar-cells
#7
Lijuan Li, Hui Lin, Xiao Kong, Xiaoyang Du, Xinwei Chen, Ling Zhou, Silu Tao, Caijun Zheng, Xiaohong Zhang
Ternary blend systems have been used to enhance the short-circuit current density (JSC) and fill factor (FF) of organic solar cells (OSCs). However, it is still a challenge to find suitable third components that concurrently possess complementary light absorption and well-matched energy levels. Here, a small organic molecule, 4,4'-(9,9-dihexyl-9H-fluorene-2,7-diyl)bis(N,N-bis(4-(pyren-1-yl)phenyl)anili-ne) (DFNPy), which contains a triphenylamine core and bulky pyrene rings, was designed and used to construct ternary blend OSCs...
May 17, 2018: Nanoscale
https://www.readbyqxmd.com/read/29770623/quality-of-tissue-from-punch-biopsy-forceps-vs-round-loop-electrode-in-colposcopically-directed-biopsy-a-randomized-controlled-trial
#8
Thanita Wetcho, Athithan Rattanaburi, Kanet Kanjanapradit
OBJECTIVE: To compare the quality of tissue from punch biopsy forceps (PB group) with round loop electrode (LE group) in colposcopically directed biopsy along with the evaluation of pain associated with each procedure. METHODS: Patients with abnormal cervical cytologic results and abnormal colposcopic findings were enrolled into a randomized trial into either a PB group or LE group. The quality of tissue was evaluated in regards to the size of tissue, site of tissue, and tissue damage...
March 12, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29770140/seventeen-year-journey-working-with-a-master
#9
Jinfang Zhu
It had been a great honor for me to work with the late Dr. William E. Paul for 17 years in the Laboratory of Immunology (LI) from 1998 until his passing in 2015. He was such a master in the immunology field. Under his outstanding guidance, my research has been focusing on transcriptional regulation of T helper (Th) cell differentiation, especially, on the role of a master transcription factor GATA3 during Th2 cell differentiation. Just as enormous scientific contributions of Dr. Paul (we all call him Bill) to the immunology community are far beyond his serving as the Chief of the LI, GATA3 also plays important roles in different lymphocytes at various developmental stages besides its critical functions in Th2 cells...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29770121/overexpression-of-thioredoxin-1-blocks-morphine-induced-conditioned-place-preference-through-regulating-the-interaction-of-%C3%AE-aminobutyric-acid-and-dopamine-systems
#10
Xiang Li, Mengbing Huang, Lihua Yang, Ningning Guo, Xiaoyan Yang, Zhimin Zhang, Ming Bai, Lu Ge, Xiaoshuang Zhou, Ye Li, Jie Bai
Morphine is one kind of opioid, which is currently the most effective widely utilized pain relieving pharmaceutical. Long-term administration of morphine leads to dependence and addiction. Thioredoxin-1 (Trx-1) is an important redox regulating protein and works as a neurotrophic cofactor. Our previous study showed that geranylgeranylaceton, an inducer of Trx-1 protected mice from rewarding effects induced by morphine. However, whether overexpression of Trx-1 can block morphine-induced conditioned place preference (CPP) in mice is still unknown...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29769819/structural-and-biomechanical-adaptations-to-free-fall-landing-in-hindlimb-cortical-bone-of-growing-female-rats
#11
Hsin-Shih Lin, Ho-Seng Wang, Hung-Ta Chiu, Kuang-You B Cheng, Ar-Tyan Hsu, Tsang-Hai Huang
The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29768536/comparison-of-platelet-rich-plasma-versus-fibrin-glue-on-colonic-anastomoses-in-rats
#12
Yusuf Kenan Daglioglu, Ozgul Duzgun, Inanc Samil Sarici, Kemal Turker Ulutas
PURPOSE: To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing. METHODS: Thirty six Wistar-Albino male rats diveded into 3 groups according to control(Group1), PRP (Group 2) and fibrin glue(Tisseel VH) (Group 3). The colon was transected with scissor and subsequently an end to end anastomosis was performed using continuous one layer 6/0 vicryl sutures. Postoperative 7th day effect of anastomotic healing measuring with tissue hydroxyproline(TH) level and anastomotic bursting pressure(ABP); moreover comparison of cytokine (IL-6 and IL-10) and procalcitonin levels on 1st,3rd and 7th days...
April 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29767672/blockade-of-tlr4-within-the-paraventricular-nucleus-attenuates-blood-pressure-by-regulating-ros-and-inflammatory-cytokines-in-prehypertensive-rats
#13
Mo-Lin Wang, Xiao-Jing Yu, Xiao-Guang Li, De-Zhi Pang, Qing Su, Roland Osei Saahene, Hong-Bao Li, Xu-Ying Mao, Kai-Li Liu, Li-Yan Fu, Ying Li, Guo-Qing Zhu, Yu-Ming Kang
Background: Toll like receptor 4 (TLR4) has been implicated in the progression of cardiovascular disease, including hypertension. However, the role of TLR4 in the development of prehypertension is uncertain. Methods: Prehypertensive rats were treated with 8% salt for 12 weeks to induce prehypertension. These rats were then given either TAK-242 selective TLR4 blocker, or vehicle by bilateral micro-injection to the paraventricular nucleus (PVN). Blood pressure and renal sympathetic nerve activity were recorded...
May 15, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29767465/salt-inflammation-il-17-and-hypertension
#14
REVIEW
Ulrich O Wenzel, Marlies Bode, Christian Kurts, Heimo Ehmke
Traditionally, arterial hypertension and subsequent end-organ damage have been attributed to hemodynamic factors, but increasing evidence indicates that inflammation also contributes to the deleterious consequences of this disease. The immune system has evolved to prevent invasion of foreign microorganisms and to promote tissue healing after injury. However, this beneficial activity comes at a cost of collateral damage when the immune system overreacts to internal injury, such as prehypertension. Over the last years important findings have revolutionized hypertension research...
May 16, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29767239/time%C3%A2-dependent-and-independent-effects-of-thyroid-hormone-administration-following-myocardial-infarction-in-rats
#15
Ioanna Iliopoulou, Iordanis Mourouzis, George I Lambrou, Dimitra Iliopoulou, Dimitrios-Dionysios Koutsouris, Constantinos Pantos
Cardiac function is reduced following myocardial infarction (MI) due to myocardial injury and alterations in the viable non‑ischemic myocardium, a process known as cardiac remodeling. The current treatments available for patients with acute MI (AMI) reduce infarct size, preserve left ventricular (LV) function and improve survival; however, these treatments do not prevent remodeling, which can lead to heart failure. The aim of the present study was to investigate the effects of thyroid hormone (TH) treatment following MI in an in vivo rat model...
May 11, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29766910/founders-of-indian-neurosciences-professor-krishna-prasad-bhargava-5-th-october-1925-16-th-august-1991
#16
Prakash N Tandon, Balram Bhargava
No abstract text is available yet for this article.
May 2018: Neurology India
https://www.readbyqxmd.com/read/29766678/association-between-bone-mineral-density-and-albuminuria-cross-sectional-analysis-of-data-from-the-2011-korea-national-health-and-nutrition-examination-survey-v-2
#17
Tae Yang Yu, Ha Young Kim, Jeong Mi Lee, Dae Ho Lee, Chung Gu Cho
BACKGROUND: Albuminuria is known to be independently associated with progression of renal and cardiovascular disease. However, little is known regarding the exact relationship between albuminuria and bone mineral density (BMD). The aim of this population-based study conducted in Korea was to identify the association between albuminuria and BMD. METHODS: We performed a cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey (KNHANES V-2) 2011...
May 4, 2018: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29766573/asymmetrical-ladder-type-donor-induced-polar-small-molecule-acceptor-to-promote-fill-factors-approaching-77-for-high-performance-nonfullerene-polymer-solar-cells
#18
Wei Gao, Miao Zhang, Tao Liu, Ruijie Ming, Qiaoshi An, Kailong Wu, Dongjun Xie, Zhenghui Luo, Cheng Zhong, Feng Liu, Fujun Zhang, He Yan, Chuluo Yang
In this work, an effectual strategy of constructing polar small molecule acceptors (SMAs) to promote fill factor (FF) of nonfullerene polymer solar cells (PSCs) is first reported. Three asymmetrical SMAs of IDT6CN, IDT6CN-Th, and IDT6CN-M, which own large dipole moments, are designed and synthesized. The PSCs based on three polar SMAs exhibit apparently higher FFs compared with their symmetrical analogues. The asymmetrical design strategy accompanied with side chain and end group engineering makes IDT6CN-Th- and IDT6CN-M-based nonfullerene PSCs achieve high power conversion efficiency with FFs approaching 77%...
May 15, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29766510/ineffectiveness-of-saxagliptin-as-a-neuroprotective-drug-in-6-ohda-lesioned-rats
#19
Joelle de Melo Turnes, Taysa Bervian Bassani, Leonardo C Souza, Maria A B F Vital
OBJECTIVES: To determine whether the drug saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor which is utilized for the treatment of Diabetes Mellitus, has neuroprotective effects in the animal model of Parkinson's disease (PD) induced by 6-hydroxydopamine (6-OHDA) in rats. METHODS: Male Wistar rats (weighing 280-300 g) received a bilateral infusion of 6-OHDA in the substantia nigra. Twenty-four hours later, they were treated with saxagliptin (1 mg/kg, p.o) once daily, for 21 days...
May 16, 2018: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29766485/abstracts-of-the-105-th-annual-congress-of-the-swiss-society-of-surgery-held-in-basel-switzerland-16-may-18-may-2018
#20
(no author information available yet)
No abstract text is available yet for this article.
May 2018: British Journal of Surgery
keyword
keyword
57720
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"