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https://www.readbyqxmd.com/read/29169145/early-results-on-canine-fetal-kidney-development-ultrasonographic-evaluation-and-value-in-prediction-of-delivery-time
#1
Elaine Mayumi Ueno Gil, Daniela Aparecida Ayres Garcia, Amália Turner Giannico, Tilde Rodrigues Froes
To date there have been no studies that describe the ultrasonographic evaluation of kidney development in canine fetuses. The aim of this prospective and longitudinal study was to monitor fetal kidney development with ultrasound and use fetal kidney measurements as a complementary biometric index for estimation of gestational age. Ultrasonographic examinations were performed on 15 clinically healthy pregnant bitches every four days from 30(th) day of pregnancy, until visualization of the fetal renal pelvis was no longer possible...
November 16, 2017: Theriogenology
https://www.readbyqxmd.com/read/29169063/measurement-of-absolute-%C3%AE-ray-emission-probabilities-in-the-decay-of-235-u
#2
M Marouli, G Lutter, S Pommé, R Van Ammel, M Hult, S Richter, R Eykens, V Peyrés, E García-Toraño, P Dryák, M Mazánová, P Carconi
Accurate measurements were performed of the photon emission probabilities following the α decay of (235)U to (231)Th. Sources of highly enriched (235)U were characterised in terms of isotopic composition by mass spectrometry and their activities were standardised by means of alpha-particle counting at a low defined solid angle. The standardised sources were subsequently measured by high-resolution γ-ray spectrometry with calibrated high-purity germanium detectors to determine the photon emission probabilities...
October 29, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29168570/specific-immunotherapy-in-lar-a-randomized-double-blind-placebo-controlled-trial-with-phleum-pratense-subcutaneous-allergen-immunotherapy
#3
Carmen Rondón, Natalia Blanca-López, Paloma Campo, Cristobalina Mayorga, Raquel Jurado-Escobar, Maria J Torres, Gabriela Canto, Miguel Blanca
BACKGROUND: Allergen immunotherapy has been shown to be an effective treatment for local allergic rhinitis (LAR) to house dust mites. Studies with pollen allergen immunotherapy are limited to observational studies. The aim of this study was to evaluate the clinical efficacy and safety of Phleum pratense subcutaneous immunotherapy (Phl-SCIT) in LAR. METHODS: In a randomized double-blind placebo-controlled study, 56 patients with moderate-severe LAR to grass pollen received Phl-SCIT with a depigmented-polymerized pollen vaccine or placebo for the first year, and Phl-SCIT the second one...
November 23, 2017: Allergy
https://www.readbyqxmd.com/read/29167969/association-of-incident-hip-fracture-with-the-estimated-femoral-strength-by-finite-element-analysis-of-dxa-scans-in-the-osteoporotic-fractures-in-men-mros-study
#4
L Yang, N Parimi, E S Orwoll, D M Black, J T Schousboe, R Eastell
Finite element model can estimate bone strength better than BMD. This study used such a model to determine its association with hip fracture risk and found that the strength estimate provided limited improvement over the hip BMDs in predicting femoral neck (FN) fracture risk only. INTRODUCTION: Bone fractures occur only when it is loaded beyond its ultimate strength. The goal of this study was to determine the association of femoral strength, as estimated by finite element (FE) analysis of DXA scans, with incident hip fracture as a single condition or with femoral neck (FN) and trochanter (TR) fractures separately in older men...
November 22, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29167770/a-multi-center-study-on-improvement-in-life-quality-of-pediatric-patients-with-asthma-via-continuous-care
#5
Ying Cai, Junhua Cao, Ruixue Kan, Yuping Liu, Li Zhao, Ming Hu, Xuemei Zhang
Background: To analyze and summarize the effect of continuous care on the life quality and control of asthma of pediatric patients with asthma discharged from multiple hospitals. Methods: Retrospective analysis was carried out on 172 pediatric patients with asthma aged between 6 and 11 yr old randomly selected from those admitted to five hospitals between January 2014 and December 2015. Among these 172 patients, only 86 (intervention group) received the continuous care between January 2015 and December 2015, while the rest (control group) did not receive from January 2014 and December 2014...
November 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29167522/isolation-and-functional-identification-of-three-cuticle-protein-genes-during-metamorphosis-of-the-beet-armyworm-spodoptera-exigua
#6
Saad Jan, Sisi Liu, Muhammad Hafeez, Xiangmei Zhang, Farman Ullah Dawar, Jiyun Guo, Chao Gao, Mo Wang
The beet armyworm, Spodoptera exigua (Hubner), is one of the major crop pests and is a target for current pest control approaches using insecticides. In this study three cuticular protein genes CPG316, CPG860 and CPG4855 have been cloned from 0 h pupal integument of S. exigua through race PCR Strategy. The deduced amino acid sequences were found to contain the RR-2 consensus region of other insect cuticular proteins and construct phylogenetic trees for each protein. Using quantitative RT-PCR, the developmental expression of the three genes through several larval and the early pupal stages was studied...
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29167495/changes-in-cardiac-arrest-patients-temperature-management-after-the-publication-of-2015-aha-guidelines-for-resuscitation-in-china
#7
Lanfang Du, Baolan Ge, Qingbian Ma, Jianzhong Yang, Fengying Chen, Yuhong Mi, Huadong Zhu, Cong Wang, Yan Li, Hongbo Zhang, Rongjia Yang, Jian Guan, Yixiong Zhang, Guiyun Jin, Haiyan Zhu, Yan Xiong, Guoxing Wang, Zhengzhong Zhu, Haiyan Zhang, Yun Zhang, Jihong Zhu, Jie Li, Chao Lan, Hui Xiong
A survey was performed to assess the current management of targeted temperature management (TTM) in patients following cardiac arrest (CA) and whether healthcare providers will change target temperature after publication of 2015 American Heart Association guidelines for resuscitation in China. 52 hospitals were selected from whole of China between August to November 2016. All healthcare providers in EMs and/or ICUs of selected hospitals participated in the study. 1952 respondents fulfilled the survey (86.8%)...
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29167151/substituted-cysteine-accessibility-and-cross-linking-identify-an-exofacial-cleft-in-the-7-th-and-8-th-helices-of-the-proton-coupled-folate-transporter-slc46a1
#8
Srinivas Aluri, Rongbao Zhao, Andras Fiser, I David Goldman
The proton-coupled folate transporter (PCFT-SLC46A1) is required for folate transport across the apical membrane of the small intestine and across the choroid plexus. This study focuses on the structure/function of the 7(th) transmembrane domain (TMD), and its relationship to the 8th TMD as assessed by the substituted cysteine accessibility method (SCAM) and dicysteine cross-linking. Nine exofacial residues (I278C; H281C-L288C) of 23 residues in the 7(th) TMD were accessible to 2-((Biotinoyl)amino)ethyl methanethiosulfonate (MTSEA-biotin)...
November 22, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/29166491/10-th-brazilian-congress-of-epidemiology-building-our-field-with-solidarity
#9
EDITORIAL
Maria Amelia de Sousa Mascena Veras, Antonio Fernando Boing
No abstract text is available yet for this article.
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29166300/effect-of-age-on-high-t1-signal-intensity-of-the-dentate-nucleus-and-globus-pallidus-in-a-large-population-exposed-to-gadodiamide
#10
Carlo Cosimo Quattrocchi, Yuri Errante, Carlo Augusto Mallio, Luca Marinelli, Gianguido LoVullo, Gabriele Giannotti, Sabino Walter Della Sala, Aart J van der Molen, Bruno Beomonte Zobel
OBJECTIVE: The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS: A large, single-center retrospective population survey was designed and received institutional review board approval. Between January 2014 and December 2014, T1w signal intensity ratios were obtained from a large population of 2500 consecutive enhanced brain magnetic resonance imaging (MRI) scans...
November 21, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/29165847/breast-lesion-characterization-using-whole-lesion-histogram-analysis-with-stretched-exponential-diffusion-model
#11
Chunling Liu, Kun Wang, Xiaodan Li, Jine Zhang, Jie Ding, Karl Spuhler, Timothy Duong, Changhong Liang, Chuan Huang
BACKGROUND: Diffusion-weighted imaging (DWI) has been studied in breast imaging and can provide more information about diffusion, perfusion and other physiological interests than standard pulse sequences. The stretched-exponential model has previously been shown to be more reliable than conventional DWI techniques, but different diagnostic sensitivities were found from study to study. PURPOSE: This work investigated the characteristics of whole-lesion histogram parameters derived from the stretched-exponential diffusion model for benign and malignant breast lesions, compared them with conventional apparent diffusion coefficient (ADC), and further determined which histogram metrics can be best used to differentiate malignant from benign lesions...
November 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29165626/the-influence-of-physical-activity-and-sedentary-behavior-on-living-to-age-85-years-without-disease-and-disability-in-older-women
#12
Eileen Rillamas-Sun, Michael J LaMonte, Kelly R Evenson, Cynthia A Thomson, Shirley A Beresford, Mathilda C Coday, Todd M Manini, Wenjun Li, Andrea Z LaCroix
Background: Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods: Participants of the Women's Health Initiative (n=49,612) were categorized based on health status by age 85 years: 1) lived without developing major chronic disease or mobility disability ("healthy"); 2) lived and developed mobility disability with or without disease; 3) lived and developed major chronic disease, but not mobility disability; and 4) died before their 85 th birth year...
November 20, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29165103/occupation-exposed-to-road-traffic-emissions-and-respiratory-health-among-congolese-transit-workers-particularly-bus-conductors-in-kinshasa-a-cross-sectional-study
#13
Etongola Papy Mbelambela, Ryoji Hirota, Masamitsu Eitoku, Sifa Marie Joelle Muchanga, Hidenori Kiyosawa, Kahoko Yasumitsu-Lovell, Ontshick Leader Lawanga, Narufumi Suganuma
OBJECTIVES: Road-traffic emissions (RTE) induce adverse health effects, notably respiratory symptoms and respiratory diseases, as a result of pollutants deposited into the respiratory tract. The aim of this study was to evaluate the association between occupation groups of Congolese transit workers exposed to RTE, particularly bus conductors and respiratory health, in Kinshasa. METHODS: A cross-sectional study was conducted from 2015 April 20(th) to May 14(th), whose participants were bus conductors (n = 110), bus drivers (n = 107), taxi-motorcyclists (n = 102) and high school teachers (control group; n = 106)...
March 20, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164410/increased-batf-expression-is-associated-with-the-severity-of-liver-damage-in-patients-with-chronic-hepatitis-b
#14
Li-Yuan Wang, Yu-Chen Fan, Jing Zhao, Xiang-Fen Ji, Kai Wang
T helper (Th) 17 cells have a critical role in the pathogenesis of chronic hepatitis B virus (HBV) infection, and basic leucine zipper transcription factor, ATF-like (BATF) is a newly identified transcriptional factor regulating the differentiation of Th17 cells. However, its precise role in patients with chronic hepatitis B remains unclear. Sixty chronic hepatitis B (CHB) patients, twenty-two acute-on-chronic hepatitis B liver failure (ACHBLF) patients and seventeen healthy controls were included in our study...
November 21, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29164146/extracorporeal-shock-wave-rebuilt-subchondral-bone-in-vivo-and-activated-wnt5a-ca-2-signaling-in-vitro
#15
Lai Yu, Shuitao Liu, Zhe Zhao, Lin Xia, Haochong Zhang, Jing Lou, Jun Yang, Gengmei Xing, Gengyan Xing
Background: This study aimed to identify the optimal extracorporeal shock wave (ESW) intensity and to investigate its effect on subchondral bone rebuilt in vivo and Wnt5a/Ca(2+) signaling in vitro using an osteoarthritis (OA) rat model and bone marrow mesenchymal stem cells (BMMSCs), respectively. Methods: OA rats treated with (OA + ESW group) or without (OA group) ESW (n = 12/group) were compared with healthy controls (control group, n = 12). Gait patterns and subchondral trabecular bone changes were measured...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29163801/long-non-coding-rna-ccat1-modulates-neuropathic-pain-progression-through-sponging-mir-155
#16
Lidong Dou, Hongqi Lin, Kaiwei Wang, Guosong Zhu, Xuli Zou, Enqiang Chang, Yongfeng Zhu
Neuropathic pain is caused by dysfunction or primary injury of the somatosensory nervous system. Long noncoding RNAs (lncRNAs) play important roles in the development of neuropathic pain. However, the effects of lncRNA colon cancer associated transcript-1 (CCAT1) in neuropathic pain have not been reported. The model of bilateral sciatic nerve chronic constriction injuries (bCCI) is regarded as long-lasting mechanical hypersensitivity and cold allodynia, which is the representative symptom in the human subjects suffering from the neuropathic pain...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163495/human-cd141-dendritic-cell-and-cd1c-dendritic-cell-undergo-concordant-early-genetic-programming-after-activation-in-humanized-mice-in-vivo
#17
Yoshihito Minoda, Isaac Virshup, Ingrid Leal Rojas, Oscar Haigh, Yide Wong, John J Miles, Christine A Wells, Kristen J Radford
Human immune cell subsets develop in immunodeficient mice following reconstitution with human CD34(+) hematopoietic stem cells. These "humanized" mice are useful models to study human immunology and human-tropic infections, autoimmunity, and cancer. However, some human immune cell subsets are unable to fully develop or acquire full functional capacity due to a lack of cross-reactivity of many growth factors and cytokines between species. Conventional dendritic cells (cDCs) in mice are categorized into cDC1, which mediate T helper (Th)1 and CD8(+) T cell responses, and cDC2, which mediate Th2 and Th17 responses...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163480/differentiation-of-il-17-producing-invariant-natural-killer-t-cells-requires-expression-of-the-transcription-factor-c-maf
#18
Jhang-Sian Yu, Michito Hamada, Shigeo Ohtsuka, Keigyou Yoh, Satoru Takahashi, Shi-Chuen Miaw
c-Maf belongs to the large Maf family of transcription factors and plays a key role in the regulation of cytokine production and differentiation of TH2, TH17, TFH, and Tr1 cells. Invariant natural killer T (iNKT) cells can rapidly produce large quantity of TH-related cytokines such as IFN-γ, IL-4, and IL-17A upon stimulation by glycolipid antigens, such as α-galactosylceramide (α-GalCer). However, the role of c-Maf in iNKT cells and iNKT cells-mediated diseases remains poorly understood. In this study, we demonstrate that α-GalCer-stimulated iNKT cells express c-Maf transcript and protein...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163149/gyy4137-an-h2s-slow-releasing-donor-prevents-nitrative-stress-and-%C3%AE-synuclein-nitration-in-an-mptp-mouse-model-of-parkinson-s-disease
#19
Xiaoou Hou, Yuqing Yuan, Yulan Sheng, Baoshi Yuan, Yali Wang, Jiyue Zheng, Chun-Feng Liu, Xiaohu Zhang, Li-Fang Hu
The neuromodulator hydrogen sulfide (H2S) was shown to exert neuroprotection in different models of Parkinson's disease (PD) via its anti-inflammatory and anti-apoptotic properties. In this study, we evaluated the effect of an H2S slow-releasing compound GYY4137 (GYY) on a mouse PD model induced by acute injection with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). GYY was intraperitoneally (i.p.) injected once daily into male C57BL/6J mice 3 days before and 2 weeks after MPTP (14 mg/kg, four times at 2-h intervals, i...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29163071/systematic-morphometry-of-catecholamine-nuclei-in-the-brainstem
#20
Domenico Bucci, Carla L Busceti, Maria T Calierno, Paola Di Pietro, Michele Madonna, Francesca Biagioni, Larisa Ryskalin, Fiona Limanaqi, Ferdinando Nicoletti, Francesco Fornai
Catecholamine nuclei within the brainstem reticular formation (RF) play a pivotal role in a variety of brain functions. However, a systematic characterization of these nuclei in the very same experimental conditions is missing so far. Tyrosine hydroxylase (TH) immune-positive cells of the brainstem correspond to dopamine (DA)-, norepinephrine (NE)-, and epinephrine (E)-containing cells. Here, we report a systematic count of TH-positive neurons in the RF of the mouse brainstem by using stereological morphometry...
2017: Frontiers in Neuroanatomy
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