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https://www.readbyqxmd.com/read/29777595/a-ring-based-compensator-imrt-system-optimized-for-low-and-middle-income-countries-design-and-treatment-planning-study
#1
Jonathon Van Schelt, Daniel Smith, Nicholas Fong, Dolla Toomeh, Patricia A Sponseller, Derek W Brown, Meghan W Macomber, Nina A Mayr, Shilpen Patel, Adam Shulman, G V Subrahmanyam, K Govindarajan, Eric C Ford
PURPOSE: We propose a novel compensator-based IMRT system designed to provide a simple, reliable, and cost-effective adjunct technology, with the goal of expanding global access to advanced radiotherapy techniques. The system would employ easily-reusable tungsten bead compensators that operate independent of a gantry (e.g. mounted in a ring around the patient). Thereby the system can be retrofitted to existing linac and cobalt teletherapy units. This study explores the quality of treatment plans from the proposed system and the dependence on associated design parameters...
May 19, 2018: Medical Physics
https://www.readbyqxmd.com/read/29663429/remote-cherenkov-imaging-based-quality-assurance-of-a-magnetic-resonance-image-guided-radiotherapy-system
#2
Jacqueline M Andreozzi, Karen E Mooney, Petr Brůža, Austen Curcuru, David J Gladstone, Brian W Pogue, Olga Green
PURPOSE: Tools to perform regular quality assurance of magnetic resonance image-guided radiotherapy (MR-IGRT) systems should ideally be independent of interference from the magnetic fields. Remotely acquired optical Cherenkov imaging-based dosimetry measurements in water were investigated for this purpose, comparing measures of dose accuracy, temporal dynamics, and overall integrated IMRT delivery. METHODS: A 40x30.5x37.5cm3 water tank doped with 1g/L of quinine sulfate was imaged using an intensified charge coupled device (ICCD) to capture the Cherenkov emission while being irradiated by a commercial MR-IGRT system (ViewRay™ )...
April 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29360150/correcting-tg-119-confidence-limits
#3
Vasant Kearney, Timothy Solberg, Shane Jensen, Joey Cheung, Cynthia Chuang, Gilmer Valdes
PURPOSE: Task Group 119 (TG-119) has been adopted for evaluating the adequacy of intensity-modulated radiation therapy (IMRT) commissioning and for establishing patient-specific IMRT quality assurance (QA) passing criteria in clinical practice. TG-119 establishes 95% confidence limits (CLs), which help clinics identify systematic IMRT QA errors and identify outliers. In TG-119, the 95% CLs are established by fitting the Gamma Γ analysis passing rate results to an assumed distribution, then calculating the limit in which 95% of the data fall...
March 2018: Medical Physics
https://www.readbyqxmd.com/read/29296041/verification-of-dosimetric-commissioning-accuracy-of-intensity-modulated-radiation-therapy-and-volumetric-modulated-arc-therapy-delivery-using-task-group-119-guidelines
#4
Karunakaran Kaviarasu, N Arunai Nambi Raj, Misba Hamid, A Ananda Giri Babu, Lingampally Sreenivas, Kammari Krishna Murthy
Aim: The purpose of this study is to verify the accuracy of the commissioning of intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) based on the recommendation of the American Association of Physicists in Medicine Task Group 119 (TG-119). Materials and Methods: TG-119 proposes a set of clinical test cases to verify the accuracy of IMRT planning and delivery system. For these test cases, we generated two sets of treatment plans, the first plan using 7-9 IMRT fields and a second plan utilizing two-arc VMAT technique for both 6 MV and 15 MV photon beams...
October 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/29214980/ion-chambers-compliance-results-of-brazilian-radiation-therapy-facilities
#5
Georgia Santos Joana, Camila Salata, Paulo Leal, Renato Oliveira, Nozimar do Couto, Flavia Cristina Teixeira, Abner Duarte Soares, Eduardo Sergio Santini, Marcello Gomes Gonçalves
Brazilian Nuclear Energy Commission (cnen) has been making a constant effort to keep updated with international standards and national needs to strengthen the status of radiological protection of the country. The guidelines related to radiation therapy facilities have been revised in the last five years in order to take in consideration the most relevant aspects of the growing technology as well as to mitigate the accidents or incidents observed in practice. Hence, clinical dosimeters have gained special importance in this matter...
December 7, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29199727/evaluation-of-dose-conformity-and-coverage-of-target-volume-for-intensity-modulated-radiotherapy-of-pelvic-cancer-treatment
#6
M Atiq, A Atiq, K Iqbal, Q Shamsi, F Andleeb, S A Buzdar
BACKGROUND: Better conformity may help in delivering minimum dose to organs at risk (OARs) and maximum dose to planning target volume (PTV). As per the requirements of modern radiotherapy, 95% isodose should cover the PTV, so conformity indices (CIs) are used for evaluating quality of conformation of treatment plans. AIM: This study aimed to investigate degree of conformity for pelvic patients using intensity-modulated radiotherapy (IMRT) technique. Three formulas of CIs described in literature were analyzed in this study...
January 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29174796/knowledge-based-treatment-planning-and-its-potential-role-in-the-transition-between-treatment-planning-systems
#7
Kathryn Masi, Paul Archer, William Jackson, Yilun Sun, Matthew Schipper, Daniel Hamstra, Martha Matuszak
Commissioning a new treatment planning system (TPS) involves many time-consuming tasks. We investigated the role that knowledge-based planning (KBP) can play in aiding a clinic's transition to a new TPS. Sixty clinically treated prostate/prostate bed intensity-modulated radiation therapy (IMRT) plans were exported from an in-house TPS and were used to create a KBP model in a newly implemented commercial application. To determine the benefit that KBP may have in a TPS transition, the model was tested on 2 groups of patients...
November 22, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29172266/dosimetric-validation-of-volumetric-modulated-arc-therapy-vmat-using-aapm-tg-119-benchmark-plans-in-an-upgraded-clinac-2100cd-for-flattening-filter-free-fff-photon-beams
#8
Ashokkumar Sangaiah, K M Ganesh, K Ramalingam, K Karthikeyan, N Jagadheeskumar
Background: Recently we have upgraded our Varian Clinac 2100CD with a 6MV FFF beam, this upgrade being the first of its kind in our country. Even though the dosimetric characteristics of FFF beams have been reported both in experimental and Monte Carlo studies, application in planning and delivery is complex. The aim of this study was to validate the commissioning of upgraded FFF beams dosimetrically using AAPM TG-119 bench mark plans for VMAT and to make a comparison with IMRT plans for both flattened filtered and FFF beams...
November 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29030203/characterization-and-clinical-evaluation-of-a-novel-2d-detector-array-for-conventional-and-flattening-filter-free-fff-imrt-pre-treatment-verification
#9
Yuvaraj Sekar, Johannes Thoelking, Miriam Eckl, Irakli Kalichava, Dwi Seno Kuncoro Sihono, Frank Lohr, Frederik Wenz, Hansjoerg Wertz
BACKGROUND AND PURPOSE: The novel MatriXX(FFF) (IBA Dosimetry, Germany) detector is a new 2D ionization chamber detector array designed for patient specific IMRT-plan verification including flattening-filter-free (FFF) beams. This study provides a detailed analysis of the characterization and clinical evaluation of the new detector array. MATERIAL AND METHODS: The verification of the MatriXX(FFF) was subdivided into (i) physical dosimetric tests including dose linearity, dose rate dependency and output factor measurements and (ii) patient specific IMRT pre-treatment plan verifications...
October 10, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/29027125/a-survey-of-modulated-radiotherapy-use-in-australia-new-zealand-in-2015
#10
Jeffrey Barber, Philip Vial, Paul White, Nick Menzies, Shrikant Deshpande, Regina Bromley, Nick Bennie, Shan Yau, Kristie Harrison
A survey of radiation oncology medical physics departments across Australia and New Zealand was conducted to assess the usage, commissioning and quality assurance of modulated radiotherapy techniques such as IMRT and VMAT. Survey responses were collected in April-May 2015 to snapshot current practice and historical implementation. The survey asked 142 questions, and is the most detailed survey of its kind published to date. Analysis of results at overall department level, as well as sub-analysis for different equipment and techniques in use, was performed...
December 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28974861/impact-of-multileaf-collimator-configuration-parameters-on-the-dosimetric-accuracy-of-6-mv-intensity-modulated-radiation-therapy-treatment-plans
#11
Nick Petersen, David Perrin, Wayne Newhauser, Rui Zhang
The purpose of this study was to evaluate the impact of selected configuration parameters that govern multileaf collimator (MLC) transmission and rounded leaf offset in a commercial treatment planning system (TPS) (Pinnacle3 , Philips Medical Systems, Andover, MA, USA) on the accuracy of intensity-modulated radiation therapy (IMRT) dose calculation. The MLC leaf transmission factor was modified based on measurements made with ionization chambers. The table of parameters containing rounded-leaf-end offset values was modified by measuring the radiation field edge as a function of leaf bank position with an ionization chamber in a scanning water-tank dosimetry system and comparing the locations to those predicted by the TPS...
July 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28944979/dosimetric-validation-of-monaco-treatment-planning-system-on-an-elekta-versahd-linear-accelerator
#12
Ganesh Narayanasamy, Daniel L Saenz, Dewayne Defoor, Niko Papanikolaou, Sotirios Stathakis
The purpose of this study is to perform dosimetric validation of Monaco treatment planning system version 5.1. The Elekta VersaHD linear accelerator with high dose rate flattening filter-free photon modes and electron energies was used in this study. The dosimetric output of the new Agility head combined with the FFF photon modes warranted this investigation into the dosimetric accuracy prior to clinical usage. A model of the VersaHD linac was created in Monaco TPS by Elekta using commissioned beam data including percent depth dose curves, beam profiles, and output factors...
September 25, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28843380/the-impact-of-intensity-modulated-radiation-therapy-plan-normalization-in-the-postprostatectomy-setting-does-it-matter
#13
Mary Anne Stritch, Elizabeth Forde, Michelle Leech
The International Commission on Radiation Units & Measurements -83 recommends prescribing intensity-modulated radiation therapy (IMRT) in a dose-volume manner. Despite this, clinical variation still exists in how prostate IMRT plans are prescribed. This study aims to investigate the impact of different plan normalization methods for postprostatectomy IMRT. IMRT treatment plans were created retrospectively for 20 postprostatectomy patients. These were normalized such that the dose received by 98% (D98) of the planning target volume (PTV) was equal to 100% of the prescribed dose...
August 23, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28438431/phantom-to-clinic-development-of-hypofractionated-stereotactic-body-radiotherapy-for-early-stage-glottic-laryngeal-cancer
#14
Chuxiong Ding, Stephen G Chun, Baran D Sumer, Lucien A Nedzi, Ramzi E Abdulrahman, John S Yordy, Pam Lee, Brian Hrycushko, Timothy D Solberg, Chul Ahn, Robert D Timmerman, David L Schwartz
The purpose of this study was to commission and clinically test a robotic stereotactic delivery system (CyberKnife, Sunnyvale, CA) to treat early-stage glottic laryngeal cancer. We enrolled 15 patients with cTis-T2N0M0 carcinoma of the glottic larynx onto an institutional review board (IRB)-approved clinical trial. Stereotactic body radiotherapy (SBRT) plans prescribed 45 Gy/10 fractions to the involved hemilarynx. SBRT dosimetry was compared with (1) standard carotid-sparing laryngeal intensity-modulated radiation therapy (IMRT) and (2) selective hemilaryngeal IMRT...
July 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28405106/evaluation-of-intensity-modulated-radiation-therapy-delivery-system-using-a-volumetric-phantom-on-the-basis-of-the-task-group-119-report-of-american-association-of-physicists-in-medicine
#15
Raphaela Avgousti, Christina Armpilia, Ioannis Floros, Christos Antypas
The current work describes the implementation of the American Association of Physicists in Medicine (AAPM)'s Task Group 119 report on a volumetric phantom (Delta(4), Scandidos, Uppsala, Sweden) following the stated dose goals, to evaluate the step-and-shoot intensity modulated radiation therapy (IMRT) system. Delta(4) consists of diode detectors, lying on two crossed planes, measuring the delivered dose, and providing two-dimensional dosimetric information. Seven plans of different goals and complexity were performed, with individual structure sets...
January 2017: Journal of Medical Physics
https://www.readbyqxmd.com/read/28300374/efficient-independent-planar-dose-calculation-for-fff-imrt-qa-with-a-bivariate-gaussian-source-model
#16
Feifei Li, Ji-Yeon Park, Brendan Barraclough, Bo Lu, Jonathan Li, Chihray Liu, Guanghua Yan
The aim of this study is to perform a direct comparison of the source model for photon beams with and without flattening filter (FF) and to develop an efficient independent algorithm for planar dose calculation for FF-free (FFF) intensity-modulated radiotherapy (IMRT) quality assurance (QA). The source model consisted of a point source modeling the primary photons and extrafocal bivariate Gaussian functions modeling the head scatter, monitor chamber backscatter, and collimator exchange effect. The model parameters were obtained by minimizing the difference between the calculated and measured in-air output factors (Sc )...
March 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297446/initial-clinical-experience-with-arccheck-for-imrt-vmat-qa
#17
Michalis Aristophanous, Yelin Suh, Pai C Chi, Luke J Whittlesey, Scott LaNeave, Mary K Martel
Many devices designed for the purpose of performing patient-specific IMRT/VMAT QA are commercially available. In this work we report our experience and initial clinical results with the ArcCHECK. The ArcCHECK consists of a cylindrical array of diode detectors measuring entry and exit doses. The measured result is a cumulative dose displayed as a 2D matrix. The detector array requires both an absolute dose calibration, and a calibration of the detector response, relative to each other. In addition to the calibrations suggested by the manufacturer, various tests were performed in order to assess its stability and performance prior to clinical introduction...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297445/implementation-of-a-double-gaussian-source-model-for-the-beamnrc-monte-carlo-code-and-its-influence-on-small-fields-dose-distributions
#18
Edgardo Doerner, Paola Caprile
The shape of the radiation source of a linac has a direct impact on the delivered dose distributions, especially in the case of small radiation fields. Traditionally, a single Gaussian source model is used to describe the electron beam hitting the target, although different studies have shown that the shape of the electron source can be better described by a mixed distribution consisting of two Gaussian components. Therefore, this study presents the implementation of a double Gaussian source model into the BEAMnrc Monte Carlo code...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297306/epid-based-dosimetry-to-verify-imrt-planar-dose-distribution-for-the-as1200-epid-and-fff-beams
#19
Narges Miri, Peter Keller, Benjamin J Zwan, Peter Greer
We proposed to perform a basic dosimetry commissioning on a new imager system, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter-free (FFF) beams, then to develop an image-based quality assurance (QA) model for verification of the system delivery accuracy for intensity-modulated radiation therapy (IMRT) treatments. For dosimetry testing, linearity of dose response with MU, imager lag, and effectiveness of backscatter shielding were investigated...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28291929/implementation-of-the-validation-testing-in-mppg-5-a-commissioning-and-qa-of-treatment-planning-dose-calculations-megavoltage-photon-and-electron-beams
#20
Dustin J Jacqmin, Jeremy S Bredfeldt, Sean P Frigo, Jennifer B Smilowitz
The AAPM Medical Physics Practice Guideline (MPPG) 5.a provides concise guidance on the commissioning and QA of beam modeling and dose calculation in radiotherapy treatment planning systems. This work discusses the implementation of the validation testing recommended in MPPG 5.a at two institutions. The two institutions worked collaboratively to create a common set of treatment fields and analysis tools to deliver and analyze the validation tests. This included the development of a novel, open-source software tool to compare scanning water tank measurements to 3D DICOM-RT Dose distributions...
January 2017: Journal of Applied Clinical Medical Physics
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