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https://www.readbyqxmd.com/read/28721947/removal-of-scatter-radiation-in-paediatric-cardiac-catheterisation-a-randomised-controlled-clinical-trial
#1
Richard Gould, Sonyia L McFadden, Andrew J Sands, Brian A McCrossan, Simon Horn, Kevin M Prise, Philip Doyle, Ciara M Hughes
This study sought to determine if DNA integrity was compromised by ionising radiation from paediatric cardiac catheterisations and if dose optimisation techniques allowed DNA integrity to be maintained. Materials and Methods: Children were imaged using either: (i) an anti-scatter grid (current departmental protocol), (ii) no anti-scatter grid or, (iii) no anti-scatter grid and a 15 cm air-gap between the child and the X-ray detector. Dose area product and image quality were assessed, lifetime attributable cancer risk estimates were calculated and DNA double-strand breakages quantified using the γH2AX assay...
July 19, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28721441/radiation-dose-to-the-operator-during-fluoroscopically-guided-spine-procedures
#2
Luca Roccatagliata, Stefano Presilla, Emanuele Pravatà, Alessandro Cianfoni
PURPOSE: Fluoroscopy is widely used to guide diagnostic and therapeutic spine procedures. The purpose of this study was to quantify radiation incident on the operator (operator Air Kerma) during a wide range of fluoroscopy-guided spine procedures and its correlation with the amount of radiation incident on the patient (Kerma Area Product-KAP). METHODS: We retrospectively included 57 consecutive fluoroscopically guided spine procedures. KAP [Gy cm(2)] and total fluoroscopy time were recorded for each procedure...
July 18, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28717826/operator-radiation-exposure-during-transradial-coronary-angiography-effect-of-single-vs-double-catheters
#3
A Tarighatnia, L Pourafkari, A Farajollahi, A H Mohammadalian, M Ghojazadeh, N D Nader
BACKGROUND: The right radial artery has gained popularity as the preferred access site for coronary angiography. To save time and limit the radiation exposure of operators and patients, newly designed catheters can be used to access both the right and left coronary arteries. The aim of this study was to compare operator radiation exposure between single-catheter (SCA) and two-catheter approaches (TCA). METHODS: In all, 256 patients undergoing diagnostic coronary angiography via the right radial artery in a high-volume medical center were randomized to either the SCA or TCA group...
July 17, 2017: Herz
https://www.readbyqxmd.com/read/28714761/gamma-irradiation-of-medicinally-important-plants-and-the-enhancement-of-secondary-metabolite-production
#4
P Vivek Vardhan, Lata I Shukla
PURPOSE: The profitable production of some important plant-based secondary metabolites (ginsenosides, saponins, camptothecin, shikonins etc.) in vitro by gamma irradiation is a current area of interest. We reviewed different types of secondary metabolites, their mode of synthesis and effect of γ-radiation on their yield for different plants, organs and in vitro cultures (callus, suspension, hairy root). Special effort has been made to review the biochemical mechanisms underlying the increase in secondary metabolites...
July 17, 2017: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/28709040/low-concentrations-of-bisphenol-a-promote-human-ovarian-cancer-cell-proliferation-and-glycolysis-based-metabolism-through-the-estrogen-receptor-%C3%AE-pathway
#5
Xiao-Yu Shi, Zhe Wang, Liyu Liu, Li-Min Feng, Nan Li, Sijin Liu, Hui Gao
Bisphenol A (BPA) is one of the most prevalent chemicals in many products used on a daily basis, making human exposure to it incredibly pervasive and raising concerns about its health consequences. One area of research focus has been the role of BPA exposure in promoting the development of ovarian cancer; however, the doses used in most of previous studies are relatively high and most likely exceed physiologically relevant levels. At the same time, few studies have described potential mechanisms underlying the link between BPA and increased cancer risk...
July 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28705704/effects-of-preoperative-simulation-on-minimally-invasive-hybrid-lumbar-interbody-fusion-mis-hlif
#6
Bernhard Rieger, Hongzhen Jiang, Clemens Reinshagen, Marek Molcanyi, Jozef Zivcak, Dietrich Grönemeyer, Bert Bosche, Gabriele Schackert, Daniel Ruess
OBJECTIVE: The main focus of this study was to evaluate how preoperative simulation affects the surgical workflow, radiation exposure and outcome of MIS-HLIF. METHODS: 132 patients who underwent single level MIS-HLIF were enrolled in a cohort study design. Dose area product was analyzed in addition to surgical data. Once preoperative simulation was established, 66 cases (SIM cohort) were compared with 66 patients who had previously undergone MIS-HLIF without preoperative simulation (NO-SIM cohort)...
July 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28705329/relationship-between-cone-beam-ct-technique-and-diagnostic-usefulness-in-patients-undergoing-embolotherapy-for-hepatocellular-carcinoma
#7
D Gutierrez, R Kishore Gurajala, B Kapoor, R Setser, K Karuppasamy
AIM: To determine the effect of different numbers of projection images in C-arm cone-beam computed tomography (CBCT) on diagnostic content and image quality in patients undergoing angiographic embolotherapy for hepatocellular carcinoma (HCC). MATERIALS AND METHODS: A total of 29 patients who underwent contrast-enhanced conventional multidetector CT (MDCT) within 6 weeks prior to CBCT acquired during embolotherapy for HCC between 2010 and 2013 were included in the study...
July 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28701167/a-combined-experimental-and-numerical-study-on-upper-airway-dosimetry-of-inhaled-nanoparticles-from-an-electrical-discharge-machine-shop
#8
Lin Tian, Yidan Shang, Rui Chen, Ru Bai, Chunying Chen, Kiao Inthavong, Jiyuan Tu
BACKGROUNDS: Exposure to nanoparticles in the workplace is a health concern to occupational workers with increased risk of developing respiratory, cardiovascular, and neurological disorders. Based on animal inhalation study and human lung tumor risk extrapolation, current authoritative recommendations on exposure limits are either on total mass or number concentrations. Effects of particle size distribution and the implication to regional airway dosages are not elaborated. METHODS: Real time production of particle concentration and size distribution in the range from 5...
July 12, 2017: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/28701014/-spacer-aerosol-therapy-through-space-and-time
#9
Thomas Voshaar, Peter Haidl, Rolf Michael Clös
Aim of the literature review Within this review, results of a literature analysis on the application of spacers with pressurized metered dose inhalers (pMDI) are described and evaluated. Methods Next to an extensive revision on effects of spacers, the impacts of current guidelines and the conditions for product authorisations on the use of spacers are described which result from the interplay of characteristics from dose inhalers with a spacer. Results Spacers are generally useful to avoid coordination problems concerning the actuation of a pMDI at the beginning of an inhalation...
July 2017: Pneumologie
https://www.readbyqxmd.com/read/28685329/impairment-of-mitochondrial-integrity-and-redox-status-in-brain-regions-during-a-low-dose-long-term-exposition-of-rats-to-pyrethrino%C3%A3-ds-the-preventive-effect-of-quercetin
#10
Afafe Beghoul, Mohamed Kebieche, Salim Gasmi, Zeyneb Chouit, Chouaib Amiour, Asma Lahouel, Zhora Lakroun, Rachid Rouabhi, Hamadi Fetoui, Rachid Soulimani
Pyrethrinoïds are synthetic pesticides widely used in agriculture and farms to protect crops from weeds, insects, fungi, and molds. Increased and uncontrolled use of these pollutants can have harmful effects on human health via consumption of contaminated food products. In the present study, deltamethrin (DLT = 3.72 mg/kg) and Bifenthrin (BF = 2.6 mg/kg) were used during a long-term exposition in the rats to assess their effect on mitochondrial integrity and function in different brain areas (hippocampus, striatum, cortex, and cerebellum)...
July 6, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28682855/management-of-a-complex-peristomal-calciphylaxis-a-case-study
#11
Mary Famorca, Debra Beauchaine, Nancy Angulo
BACKGROUND: Calciphylaxis, also referred to as calcific uremic arteriolopathy, is a rare and serious syndrome of small blood vessels with a high mortality rate. Calciphylaxis lesions require intensive wound management with medical interventions for the patient to survive the sequelae of sepsis and present unique challenges when found in the peristomal skin. CASE: A 33-year-old man presented with multiple malodorous stage 4 pressure injuries of his sacrococcygeal and gluteal area...
July 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28677594/optimization-of-imaging-protocols-in-interventional-cardiology-impact-on-patient-doses
#12
José Manuel Ordiales, Eliseo Vano, Juan Manuel Nogales, José Ramos, José Ramón López-Mínguez, Ginés Martínez, Pablo Cerrato, Fernando Alvarez
The purpose of this work is to evaluate the impact of the imaging protocol as part of the optimization of patient doses in interventional cardiology. This paper reports the results of an initial study to refine the existing fluoroscopy and cine settings, evaluates a new imaging protocol by measuring the image quality and phantom entrance air kerma values, and tests the clinical implementation of the new protocol in terms of the reduction in patient doses and the impact on clinical images. The initial study developed a new fluoroscopy mode using 7...
July 5, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28672975/the-protective-effect-of-ginsenoside-rg1-on-aging-mouse-pancreas-damage-induced-by-d-galactose
#13
Zhaoying Dong, Mengxiong Xu, Jie Huang, Linbo Chen, Jieyu Xia, Xiongbin Chen, Rong Jiang, Lu Wang, Yaping Wang
The protective effect and mechanism of Ginsenoside Rg1 on aging mouse pancreas damaged by D-galactose (D-gal)-induced was studied. Two-month-old male C57BL/6J mice were randomly divided into three groups of 10 mice per group. The D-gal group of mice received hypodermic injection of D-gal (120 mg/kg/day) for 42 days; the Rg1+D-gal group of mice receiving D-gal + intraperitoneal injection Rg1 (40 mg/kg/day) for 27 days from the 16th day of D-gal replication; and the naïve group that constituted the normal control mice receiving the same dose of saline instead of the drug...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28671713/complement-c5a-induced-changes-in-neutrophil-morphology-during-inflammation
#14
Stephanie Denk, Ronald P Taylor, Rebecca Wiegner, Erika M Cook, Margaret A Lindorfer, Katharina Pfeiffer, Stephan Paschke, Tim Eiseler, Manfred Weiss, Eberhard Barth, John D Lambris, Miriam Kalbitz, Tobias Martin, Holger Barth, David A C Messerer, Florian Gebhard, Markus S Huber-Lang
The complement and neutrophil defense systems, as major components of innate immunity, are activated during inflammation and infection. For neutrophil migration to the inflamed region, we hypothesized that the complement activation product C5a induces significant changes in cellular morphology before chemotaxis. Exposure of human neutrophils to C5a, dose- and time-dependently resulted in a rapid C5a receptor-1 (C5aR1)-dependent shape-change, indicated by enhanced flow cytometric forward-scatter area values...
June 30, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28670525/melatonin-ameliorates-the-production-of-cox-2-inos-and-the-formation-of-8-ohdg-in-non-targeted-lung-tissue-after-pelvic-irradiation
#15
Reza Fardid, Ashkan Salajegheh, Mohammad Amin Mosleh-Shirazi, Sedigheh Sharifzadeh, Mohammad Ali Okhovat, Masoud Najafi, Abolhasan Rezaeyan, Akbar Abaszadeh
In this study, we evaluated the bystander effect of radiation on the regulation of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and 8-hydroxydeoxyguanosine (8-OHdG) in lung tissues of Sprague-Dawley rats with and without pre-administration of melatonin. A 2×2 cm(2) area of the pelvis of male Sprague-Dawley rats with and without pre-administration of melatonin (100 mg/kg) by oral and intraperitoneal injection was irradiated with a 3 Gy dose of 1.25 MeV γ-rays. Alterations in the levels of COX-2, iNOS, and 8-OHdG in the out-of-field lung areas of the animals were detected by enzyme immunoassay...
July 2017: Cell Journal
https://www.readbyqxmd.com/read/28670167/radiation-dose-reduction-without-compromise-to-image-quality-by-alterations-of-filtration-and-focal-spot-size-in-cerebral-angiography
#16
Dong Joon Kim, Min Keun Park, Da Eun Jung, Jung Han Kang, Byung Moon Kim
OBJECTIVE: Different angiographic protocols may influence the radiation dose and image quality. In this study, we aimed to investigate the effects of filtration and focal spot size on radiation dose and image quality for diagnostic cerebral angiography using an in-vitro model and in-vivo patient groups. MATERIALS AND METHODS: Radiation dose and image quality were analyzed by varying the filtration and focal spot size on digital subtraction angiography exposure protocols (1, inherent filtration + large focus; 2, inherent + small; 3, copper + large; 4, copper + small)...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28665344/sustainable-use-of-pesticide-applications-in-citrus-a-support-tool-for-volume-rate-adjustment
#17
Cruz Garcerá, Alberto Fonte, Enrique Moltó, Patricia Chueca
Rational application of pesticides by properly adjusting the amount of product to the actual needs and specific conditions for application is a key factor for sustainable plant protection. However, current plant protection product (PPP) labels registered for citrus in EU are usually expressed as concentration (%; rate/hl) and/or as the maximum dose of product per unit of ground surface, without taking into account those conditions. In this work, the fundamentals of a support tool, called CitrusVol, developed to recommend mix volume rates in PPP applications in citrus orchards using airblast sprayers, are presented...
June 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28664494/can-liming-change-root-anatomy-biomass-allocation-and-trace-element-distribution-among-plant-parts-of-salix-%C3%A3-smithiana-in-trace-element-polluted-soils
#18
Stanislava Vondráčková, Pavel Tlustoš, Jiřina Száková
Willows (Salix spp.) are considered to be effective for the phytoremediation of trace elements from contaminated soils, but their efficiency is limited in heavily polluted soils because of poor growth. Liming can be a desirable measure to decrease the plant availability of elements, resulting in improved plant development. Notably, large root area and maximum soil penetration are basic parameters that improve the efficiency of phytoremediation. The impact of soil chemical properties on willow root anatomy and the distribution of trace elements below-ground have rarely been studied...
June 29, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28662690/comparative-efficacy-of-a-new-spot-on-combination-product-containing-selamectin-and-sarolaner-stronghold%C3%A2-plus-versus-fluralaner-bravecto%C3%A2-against-induced-infestations-with-ixodes-ricinus-ticks-on-cats
#19
Thomas Geurden, Stasia Borowski, Magda Wozniakiewicz, Vickie King, Josephus Fourie, Julian Liebenberg
BACKGROUND: Ticks are increasingly reported on cats worldwide, with Ixodes ricinus being a relevant species across Europe and in near by areas of North Africa and the Middle East. Yet there are few acaracidal products with proven efficacy approved for use in cats. The objective of this study was to compare the efficacy of a new spot-on formulation containing selamectin and sarolaner with a topical application of fluralaner (Bravecto®) against Ixodes ricinus ticks on cats. To that end, twenty-four (24) cats were randomly allocated to one of three treatment groups...
June 29, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28659776/cholinergic-potentiation-and-audiovisual-repetition-imitation-therapy-improve-speech-production-and-communication-deficits-in-a-person-with-crossed-aphasia-by-inducing-structural-plasticity-in-white-matter-tracts
#20
Marcelo L Berthier, Irene De-Torres, José Paredes-Pacheco, Núria Roé-Vellvé, Karl Thurnhofer-Hemsi, María J Torres-Prioris, Francisco Alfaro, Ignacio Moreno-Torres, Diana López-Barroso, Guadalupe Dávila
Donepezil (DP), a cognitive-enhancing drug targeting the cholinergic system, combined with massed sentence repetition training augmented and speeded up recovery of speech production deficits in patients with chronic conduction aphasia and extensive left hemisphere infarctions (Berthier et al., 2014). Nevertheless, a still unsettled question is whether such improvements correlate with restorative structural changes in gray matter and white matter pathways mediating speech production. In the present study, we used pharmacological magnetic resonance imaging to study treatment-induced brain changes in gray matter and white matter tracts in a right-handed male with chronic conduction aphasia and a right subcortical lesion (crossed aphasia)...
2017: Frontiers in Human Neuroscience
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