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https://www.readbyqxmd.com/read/29350914/cys34-adductomes-differ-between-patients-with-chronic-lung-or-heart-disease-and-healthy-controls-in-central-london
#1
Sa Liu, Hasmik Grigoryan, William Matthew Bell Edmands, Sonia Dagnino, Rudy Sinharay, Paul Cullinan, Peter Collins, Kian Fan Chung, Benjamin M Barratt, Frank J Kelly, Paolo Vineis, Stephen M Rappaport
Oxidative stress generates reactive species that modify proteins, deplete antioxidant defenses and contribute to chronic obstructive pulmonary disease (COPD) and ischemic heart disease (IHD). To determine whether protein modifications differ between COPD or IHD patients and healthy subjects, we performed untargeted analysis of adducts at the Cys34 locus of human serum albumin (HSA). Biospecimens were obtained from nonsmoking participants from London, U.K., including healthy subjects (n=20) and patients with COPD (n=20) or IHD (n=10)...
January 19, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29343860/predicted-impact-of-thermal-power-generation-emission-control-measures-in-the-beijing-tianjin-hebei-region-on-air-pollution-over-beijing-china
#2
Liqiang Wang, Pengfei Li, Shaocai Yu, Khalid Mehmood, Zhen Li, Shucheng Chang, Weiping Liu, Daniel Rosenfeld, Richard C Flagan, John H Seinfeld
Widespread economic growth in China has led to increasing episodes of severe air pollution, especially in major urban areas. Thermal power plants represent a particularly important class of emissions. Here we present an evaluation of the predicted effectiveness of a series of recently proposed thermal power plant emission controls in the Beijing-Tianjin-Hebei (BTH) region on air quality over Beijing using the Community Multiscale Air Quality(CMAQ) atmospheric chemical transport model to predict CO, SO2, NO2, PM2...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342195/association-between-pm10-pm2-5-no2-o3-and-self-reported-diabetes-in-italy-a-cross-sectional-ecological-study
#3
Riccardo Orioli, Giuseppe Cremona, Luisella Ciancarella, Angelo G Solimini
INTRODUCTION: Air pollution represents a serious threat to health on a global scale, being responsible for a large portion of the global burden of disease from environmental factors. Current evidence about the association between air pollution exposure and Diabetes Mellitus (DM) is still controversial. We aimed to evaluate the association between area-level ambient air pollution and self-reported DM in a large population sample in Italy. MATERIALS AND METHODS: We extracted information about self-reported and physician diagnosed DM, risk factors and socio-economic status from 12 surveys conducted nationwide between 1999 and 2013...
2018: PloS One
https://www.readbyqxmd.com/read/29341949/impact-of-air-pollution-and-outdoor-temperature-on-the-rate-of-chronic-obstructive-pulmonary-disease-exacerbations
#4
Iliya I Krachunov, Nikolay H Kyuchukov, Zlatina I Ivanova, Nikolay A Yanev, Petkana A Hristova, Elena D Borisova, Tsanya P Popova, Plamen S Pavlov, Pavlina T Nikolova, Yavor Y Ivanov
BACKGROUND: Environmental pollution can be one of the main risk factors for acute exacerbations of chronic obstructive pulmonary disease (COPD). AIM: To study the relationship between air pollution, outdoor temperature and exacerbations of COPD. MATERIALS AND METHODS: COPD patients (n=1432) were followed up for one year. The levels of particulate matter up to 10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2) and outside temperatures were collected from the Environmental Agency database...
December 20, 2017: Folia Medica
https://www.readbyqxmd.com/read/29337319/the-effects-of-interaction-between-particulate-matter-and-temperature-on-mortality-in-beijing-china
#5
Lin Tian, Fengchao Liang, Qun Guo, Shi Chen, Shengning Xiao, Ziting Wu, Xiaobin Jin, Xiaochuan Pan
BACKGROUND: the effects of interaction between temperature and inhalable particulate matter (aerodynamic diameter < 10 μm, PM10) on mortality have been examined in some previous studies, but the results were inconsistent. This study aims to explore whether the effects of PM10 on daily non-accidental, cardiovascular and respiratory mortality were modified by temperature levels in Beijing from 2006 to 2009. METHODS: we applied a bivariate response surface model and temperature-stratified model based on time-series Poisson generalized additive models (GAMs) to examine the interactive effects in single- and two-pollutant models...
January 16, 2018: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/29331891/global-association-between-ambient-air-pollution-and-blood-pressure-a-systematic-review-and-meta-analysis
#6
REVIEW
Bo-Yi Yang, Zhengmin Qian, Steven W Howard, Michael G Vaughn, Shu-Jun Fan, Kang-Kang Liu, Guang-Hui Dong
Although numerous studies have investigated the association of ambient air pollution with hypertension and blood pressure (BP), the results were inconsistent. We performed a comprehensive systematic review and meta-analysis of these studies. Seven international and Chinese databases were searched for studies examining the associations of particulate (diameter<2.5 μm (PM2.5), 2.5-10 μm (PM2.5-10) or >10 μm (PM10)) and gaseous (sulfur dioxide (SO2), nitrogen dioxide (NO2), nitrogen oxides (NOx), ozone (O3), carbon monoxide (CO)) air pollutants with hypertension or BP...
January 11, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29321054/the-association-between-daily-concentrations-of-air-pollution-and-visits-to-a-psychiatric-emergency-unit-a-case-crossover-study
#7
Anna Oudin, Daniel Oudin Åström, Peter Asplund, Steinn Steingrimsson, Zoltan Szabo, Hanne Krage Carlsen
BACKGROUND: Air pollution is one of the leading causes of mortality and morbidity worldwide. Experimental studies, and a few epidemiological studies, suggest that air pollution may cause acute exacerbation of psychiatric disorders, and even increase the rate of suicide attempts, but epidemiological studies on air pollution in association with psychiatric disorders are still few. Our aim was to investigate associations between daily fluctuations in air pollution concentrations and the daily number of visits to a psychiatric emergency unit...
January 10, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29319630/exposure-to-ambient-ultrafine-particles-and-nitrogen-dioxide-and-incident-hypertension-and-diabetes
#8
Li Bai, Hong Chen, Marianne Hatzopoulou, Michael Jerrett, Jeffrey C Kwong, Richard T Burnett, Aaron van Donkelaar, Ray Copes, Randall V Martin, Keith van Ryswyk, Hong Lu, Alexander Kopp, Scott Weichenthal
BACKGROUND: Previous studies reported that long-term exposure to traffic-related air pollution may increase the incidence of hypertension and diabetes. However, little is known about the associations of ultrafine particles (≤0.1 micrometers in diameter) with these two conditions. METHODS: We conducted a population-based cohort study to investigate the associations between exposures to ultrafine particles and nitrogen dioxide (NO2) and the incidence of diabetes and hypertension...
January 9, 2018: Epidemiology
https://www.readbyqxmd.com/read/29317916/exposure-to-no2-co-and-pm2-5-is-linked-to-regional-dna-methylation-differences-in-asthma
#9
Mary Prunicki, Laurel Stell, Deendayal Dinakarpandian, Mariangels de Planell-Saguer, Richard W Lucas, S Katharine Hammond, John R Balmes, Xiaoying Zhou, Tara Paglino, Chiara Sabatti, Rachel L Miller, Kari C Nadeau
Background: DNA methylation of CpG sites on genetic loci has been linked to increased risk of asthma in children exposed to elevated ambient air pollutants (AAPs). Further identification of specific CpG sites and the pollutants that are associated with methylation of these CpG sites in immune cells could impact our understanding of asthma pathophysiology. In this study, we sought to identify some CpG sites in specific genes that could be associated with asthma regulation (Foxp3 and IL10) and to identify the different AAPs for which exposure prior to the blood draw is linked to methylation levels at these sites...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29304467/vertical-variation-of-pm2-5-mass-and-chemical-composition-particle-size-distribution-no2-and-btex-at-a-high-rise-building
#10
Stefano Zauli Sajani, Stefano Marchesi, Arianna Trentini, Dimitri Bacco, Claudia Zigola, Sabrina Rovelli, Isabella Ricciardelli, Claudio Maccone, Paolo Lauriola, Domenico Maria Cavallo, Vanes Poluzzi, Andrea Cattaneo, Roy M Harrison
Substantial efforts have been made in recent years to investigate the horizontal variability of air pollutants at regional and urban scales and epidemiological studies have taken advantage of resulting improvements in exposure assessment. On the contrary, only a few studies have investigated the vertical variability and their results are not consistent. In this study, a field experiment has been conducted to evaluate the variation of concentrations of different particle metrics and gaseous pollutants on the basis of floor height at a high rise building...
January 2, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29299924/high-performance-colorimetric-carbon-monoxide-sensor-for-continuous-personal-exposure-monitoring
#11
Chenwen Lin, Xiaojun Xian, Xingcai Qin, Di Wang, Francis Tsow, Erica S Forzani, Nongjian Tao
Carbon monoxide (CO) is a highly poisonous gas, which can cause serious health risk. CO monitoring helps protect us from excessive exposure at home and in the workplace, and reduce occupation-related health risks for workers. Conventional electrochemical and metal oxide semiconductors (MOS) based CO sensors have been widely used, but the drawbacks such as poor selectivity and calibration burden also limit their applications, e.g. as wearable exposure monitors. Aiming at the reliable, miniaturized, and easy-to-use personal exposure device development, we report a colorimetric CO sensing platform, which achieves a detection limit of 1 ppm, dynamic range of 0 ~ 500 ppm, and high selectivity to CO over common interferents in air, such as CO2, NO2, SO2, and O3...
January 4, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29298278/the-impact-of-air-pollution-to-central-nervous-system-in-children-and-adults
#12
Radim J Sram, Milos Veleminsky, Milos Veleminsky, Jana Stejskalová
The aim of this paper was to review studies analyzing the associations between air pollution and neurodevelopment in children as well as the effect on adult population. Effect of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs, benzo[a]pyrene, B[a]P) were already studied on cohorts from New York, Poland, China, and Spain. All results indicate changes of child behavior and neurodevelopment at the age of 3-9 years, decrease of IQ, increase of Attention Deficit Hyperactivity Disorder (ADHD), decrease of brain-derived neurotrophic factor (BDNF), reduction of left hemisphere white matter...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29289783/air-pollutants-and-asthma-patient-visits-indication-of-source-influence
#13
Huibin Guo, Sijing Huang, Minxuan Chen
BACKGROUND: Sources of air pollutants are significant factors for adverse health effect. Few current studies explored the linking of sources influence and ambient pollutants to asthma patient visits in Shanghai, China. OBJECTIVES: This study explored the associations between short-term exposures to ambient pollutants and asthma morbidity with terrestrial and marine source influence in Shanghai. METHODS: Generalized additive model (GAM) was used to explore the association of daily patient visits and ambient pollutants...
December 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29288255/assessment-of-indoor-air-quality-at-an-electronic-cigarette-vaping-convention
#14
Rui Chen, Angela Aherrera, Chineye Isichei, Pablo Olmedo, Stephanie Jarmul, Joanna E Cohen, Ana Navas-Acien, Ana M Rule
E-cigarette (vaping) conventions are public events promoting electronic cigarettes, in which indoor use of e-cigarettes is allowed. The large concentration of people using e-cigarettes and poor air ventilation can result in indoor air pollution. In order to estimate this worst-case exposure to e-cigarettes, we evaluated indoor air quality in a vaping convention in Maryland (MD), USA. Real-time concentrations of particulate matter (PM10) and real-time total volatile organic compounds (TVOCs), CO2 and NO2 concentrations were measured...
December 29, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29285630/preeclampsia-and-hypertension-during-pregnancy-in-areas-with-relatively-low-levels-of-traffic-air-pollution
#15
Christian Madsen, Siri Eldevik Håberg, Geir Aamodt, Hein Stigum, Per Magnus, Stephanie J London, Wenche Nystad, Per Nafstad
Objectives Air pollution exposure may contribute to the development of preeclampsia and hypertension during pregnancy. However, the evidence for such a relation is still limited. We investigated the associations between exposure for moderate to low levels of air pollution during pregnancy and preeclampsia and gestational hypertension in selected urban and county areas of Norway. Methods This study used a sub-group of 17,533 women in the Norwegian Mother and Child Cohort Study. Air pollution levels at residential addresses were estimated using land use regression models and back-extrapolated to the period of each pregnancy...
December 28, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29283681/short-term-air-pollution-and-incident-pneumonia-a-case-crossover-study
#16
Cheryl S Pirozzi, Barbara E Jones, James A VanDerslice, Yue Zhang, Robert Paine, Nathan C Dean
RATIONALE: The relationship between air pollution and pneumonia is poorly understood. OBJECTIVES: To examine relationships between short-term air pollution exposure and number and severity of pneumonia cases along the Wasatch Front in Utah, USA, a region with periodic high levels of outdoor air pollution. METHODS: We applied time-stratified case-crossover analyses with distributed lag to patients presenting to 7 emergency departments (EDs) with pneumonia over 2 years...
December 28, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29282255/pregnancy-exposure-to-air-pollution-and-early-childhood-respiratory-health-in-the-norwegian-mother-and-child-cohort-study-moba
#17
Christian Madsen, Siri Eldevik Haberg, Maria C Magnus, Geir Aamodt, Hein Stigum, Stephanie J London, Wenche Nystad, Per Nafstad
OBJECTIVES: It is unclear whether maternal air pollution exposure during pregnancy induces changes in the developing respiratory system of a child and whether it has consequences for respiratory health in early childhood. We investigated associations between exposure to moderate levels of air pollution during pregnancy and early childhood lower respiratory tract infections (LRTI) and wheezing. METHODS: This study used a subgroup of 17 533 participants in the Norwegian Mother and Child Cohort Study...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29278810/asthma-prevalence-and-school-related-hazardous-air-pollutants-in-the-us-m%C3%A3-xico-border-area
#18
Genny Carrillo, Maria J Perez Patron, Natalie Johnson, Yan Zhong, Rose Lucio, Xiaohui Xu
BACKGROUND: Asthma is the most common chronic disease in children and has been linked to high levels of ambient air pollution and certain hazardous air pollutants (HAPs). Outdoor pollutants such as benzene, released by car emissions, and organic chemicals found in diesel exhaust, as well as particles and irritant gases, including nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3), contribute to an increased prevalence of respiratory diseases such as asthma. OBJECTIVES: The objectives of this study were to: 1) conduct a screening survey to identify high risk for asthma among school-age children in Hidalgo County, and, 2) study the potential health impact of school-related exposure to HAPs pertaining to asthma risk...
December 23, 2017: Environmental Research
https://www.readbyqxmd.com/read/29248851/traffic-related-air-pollution-associated-with-chronic-kidney-disease-among-elderly-residents-in-taipei-city
#19
Szu-Ying Chen, Da-Chen Chu, Jui-Huan Lee, Ya-Ru Yang, Chang-Chuan Chan
The associations of air pollution with chronic kidney disease (CKD) have not yet been fully studied. We enrolled 8,497 Taipei City residents older than 65 years and calculated the estimated glomerular filtration rate (eGFR) using the Taiwanese Chronic Kidney Disease Epidemiology Collaboration equation. Proteinuria was assessed via dipstick on voided urine. CKD prevalence and risk of progression were defined according to the KDIGO 2012 guidelines. Land-use regression models were used to estimate the participants' one-year exposures to PM of different sizes and traffic-related exhaust, PM2...
December 14, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29241157/allergenicity-of-recombinant-humulus-japonicus-pollen-allergen-1-after-combined-exposure-to-ozone-and-nitrogen-dioxide
#20
Qiang Hong, Shumin Zhou, Hui Zhao, Jiaxian Peng, Yang Li, Yu Shang, Minghong Wu, Wei Zhang, Senlin Lu, Shuijun Li, Shen Yu, Weiqian Wang, Qingyue Wang
Ozone (O3) and nitrogen dioxide (NO2) are thought to play primary roles in aggravating air pollution-induced health problems. However, the effects of joint O3/NO2 on the allergenicity of pollen allergens are unclear. Humulus japonicus pollen allergen 1 (Hum j1) is a profilin protein that causes widespread pollinosis in eastern Asia. In order to study the effects of combined O3/NO2 on the allergenicity of Hum j1, tandem six-histidine peptide tag (His6)-fused recombinant Hum j1 (rHum j1) was expressed in a prokaryotic system and purified through His6 affinity chromatography...
December 11, 2017: Environmental Pollution
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