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osteoporosis epidemiology

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https://www.readbyqxmd.com/read/28932373/cohort-profile-update-the-amirkola-health-and-ageing-project-ahap
#1
Ali Bijani, Reza Ghadimi, Ebrahim Mikaniki, Farzan Kheirkhah, Seyyed Ali Mozaffarpur, Mina Motallebnejad, Haleh Esmaili, Fatemeh Majidi, Robert Graham Cumming, Seyed Reza Hosseini
The original cohort study of AHAP started in 2011 on 1616 elderly residents of Amirkola, northern part of Iran near the Caspian Sea. The main goal of this study was to comprehensively evaluate the health of the elderly in the region with the emphasis on chronic diseases such as osteoporosis. The first cohort profile was published in the International Journal of Epidemiology in 2014. The phase 1 AHAP showed the elevated level of some diseases and conditions including osteoporosis, metabolic syndrome, obesity, vision problems and relatively low levels of oral health...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28930173/polyphenols-from-root-tubercles-and-grains-cropped-in-brazil-chemical-and-nutritional-characterization-and-their-effects-on-human-health-and-diseases
#2
REVIEW
Diego Dos Santos Baião, Cyntia Silva de Freitas, Laidson Paes Gomes, Davi da Silva, Anna Carolina N T F Correa, Patricia Ribeiro Pereira, Eduardo Mere Del Aguila, Vania Margaret Flosi Paschoalin
Throughout evolution, plants have developed the ability to produce secondary phenolic metabolites, which are important for their interactions with the environment, reproductive strategies and defense mechanisms. These (poly)phenolic compounds are a heterogeneous group of natural antioxidants found in vegetables, cereals and leguminous that exert beneficial and protective actions on human health, playing roles such as enzymatic reaction inhibitors and cofactors, toxic chemicals scavengers and biochemical reaction substrates, increasing the absorption of essential nutrients and selectively inhibiting deleterious intestinal bacteria...
September 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28913616/bone-phenotype-assessed-by-hrpqct-and-associations-with-fracture-risk-in-the-glow-study
#3
A E Litwic, L D Westbury, D E Robinson, K A Ward, C Cooper, E M Dennison
The epidemiology and pathogenesis of fractures in postmenopausal women has previously been investigated in the Global Longitudinal study of Osteoporosis in Women (GLOW). To date, however, relationships between bone imaging outcomes and fracture have not been studied in this cohort. We examined relationships between high-resolution peripheral quantitative computed tomography (HRpQCT) parameters and fracture in the UK arm of GLOW, performing a cluster analysis to assess if our findings were similar to observations reported from older participants of the Hertfordshire Cohort Study (HCS), and extended the analysis to include tibial measurements...
September 14, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28913546/economic-burden-of-osteoporosis-in-south-korea-claim-data-of-the-national-health-insurance-service-from-2008-to-2011
#4
Yong-Chan Ha, Ha-Young Kim, Sunmee Jang, Young-Kyun Lee, Tae-Young Kim
The purpose of this study was to estimate the current economic burden of osteoporosis in South Korea using national claim data of the Korean National Health Insurance Service (KNHIS) from 2008 to 2011. Patients aged 50 years or older were identified from KNHIS nationwide database for all records of outpatient visits or hospital admissions. Healthcare costs for osteoporotic patients included direct medical costs for hospitalization, outpatient care, and prescription drugs for the year after discharge. Healthcare costs were estimated based on the perspective of KNHIS, and calculated using a bottom-up approach...
September 14, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28891093/tocotrienols-for-bone-health-a-translational-approach
#5
REVIEW
Chwan-Li Shen, Annika Klein, Kok-Yong Chin, Huanbiao Mo, Peihsuan Tsai, Rong-Sen Yang, Ming-Chien Chyu, Soelaiman Ima-Nirwana
Osteoporosis, a degenerative bone disease, is characterized by low bone mass and microstructural deterioration of bone tissue resulting in aggravated bone fragility and susceptibility to fractures. The trend of extended life expectancy is accompanied by a rise in the prevalence of osteoporosis and concomitant complications in the elderly population. Epidemiological evidence has shown an association between vitamin E consumption and the prevention of age-related bone loss in elderly women and men. Animal studies show that ingestion of vitamin E, especially tocotrienols, may benefit bone health in terms of maintaining higher bone mineral density and improving bone microstructure and quality...
August 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28860860/positive-predictive-values-of-icd-10-codes-to-identify-incident-acute-pancreatitis-and-incident-primary-malignancy-in-the-scandinavian-national-patient-registries-among-women-with-postmenopausal-osteoporosis
#6
Troels Munch, Lotte B Christensen, Kasper Adelborg, Grethe S Tell, Ellen M Apalset, Anna Westerlund, Ylva T Lagerros, Johnny Kahlert, Fei Xue, Vera Ehrenstein
BACKGROUND: Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify cases of incident acute pancreatitis leading to hospitalization and incident primary malignancy in the Scandinavian (Denmark, Norway, and Sweden) national patient registries in women with postmenopausal osteoporosis (PMO)...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28816877/fractures-in-spinal-ankylosing-disorders-a-narrative-review-of-disease-and-injury-types-treatment-techniques-and-outcomes
#7
Tarush Rustagi, Doniel Drazin, Cumhur Oner, Jonathan York, Gregory D Schroeder, Alexander R Vaccaro, Rod J Oskouian, Jens R Chapman
INTRODUCTION: Spinal ankylosing disorders encompass ankylosing spondylitis (AS), disseminated hyperostosis of the spine, and end-stage spondylosis. All these result in a stiffened and frequently deformed spinal column. This makes the spinal column highly susceptible to severe injuries that are commonly associated with unfavorable outcomes. Improved understanding of the underlying disease processes and clinical comorbidities may alter the poor injury related morbidity and mortality outcomes...
September 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28806178/vitamin-d-and-osteosarcopenia-an-update-from-epidemiological-studies
#8
Olivier Bruyère, Etienne Cavalier, Jean-Yves Reginster
PURPOSE OF REVIEW: The review summarizes recent epidemiological studies that examined the relationship between osteoporosis and sarcopenia to assess the impact of vitamin D status or supplementation on health outcomes related to these two medical conditions. RECENT FINDINGS: Osteoporosis and sarcopenia are major public health problems, but whether these two diseases should be considered alone or combined into a single condition is not clear. No consensual definition of osteosarcopenia is largely accepted...
September 15, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28780676/erratum-to-osteoporosis-obesity-and-sarcopenia-on-abdominal-ct-a-review-of-epidemiology-diagnostic-criteria-and-management-strategies-for-the-reporting-radiologist
#9
Timothy É Murray, David Williams, Michael J Lee
No abstract text is available yet for this article.
August 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28771175/association-between-mastication-the-hippocampus-and-the-hpa-axis-a-comprehensive-review
#10
REVIEW
Kagaku Azuma, Qian Zhou, Masami Niwa, Kin-Ya Kubo
Mastication is mainly involved in food intake and nutrient digestion with the aid of teeth. Mastication is also important for preserving and promoting general health, including hippocampus-dependent cognition. Both animal and human studies indicate that mastication influences hippocampal functions through the end product of the hypothalamic-pituitary-adrenal (HPA) axis, glucocorticoid (GC). Epidemiologic studies suggest that masticatory dysfunction in aged individuals, such as that resulting from tooth loss and periodontitis, acting as a source of chronic stress, activates the HPA axis, leading to increases in circulating GCs and eventually inducing various physical and psychological diseases, such as cognitive impairment, cardiovascular disorders, and osteoporosis...
August 3, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28734709/worldwide-fracture-prediction
#11
Ghada El-Hajj Fuleihan, Marlene Chakhtoura, Jane A Cauley, Nariman Chamoun
The substantial increase in the burden of non-communicable diseases in general and osteoporosis in particular, necessitates the establishment of efficient and targeted diagnosis and treatment strategies. This chapter reviews and compares different tools for osteoporosis screening and diagnosis; it also provides an overview of different treatment guidelines adopted by countries worldwide. While access to dual-energy X-ray absorptiometry to measure bone mineral density (BMD) is limited in most areas in the world, the introduction of risk calculators that combine risk factors, with or without BMD, have resulted in a paradigm shift in osteoporosis screening and management...
July 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28733716/osteosarcopenia-where-bone-muscle-and-fat-collide
#12
REVIEW
H P Hirschfeld, R Kinsella, G Duque
As the world's population ages, the prevalence of chronic diseases increases. Sarcopenia and osteoporosis are two conditions that are associated with aging, with similar risk factors that include genetics, endocrine function, and mechanical factors. Additionally, bone and muscle closely interact with each other not only anatomically, but also chemically and metabolically. Fat infiltration, a phenomenon observed in age-related bone and muscle loss, is highly prevalent and more severe in sarcopenic and osteoporotic subjects...
July 22, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28721974/hepatitis-c-virus-infection-and-risk-of-osteoporosis-a-meta-analysis
#13
REVIEW
Karn Wijarnpreecha, Charat Thongprayoon, Panadeekarn Panjawatanan, Parkpoom Phatharacharukul, Patompong Ungprasert
BACKGROUND/AIMS: Hepatitis C virus (HCV) infection is one of the most common infections worldwide. Several epidemiologic studies have suggested that patients with HCV infection might be at an increased risk of osteoporosis. However, the data on this relationship remains inconclusive. This meta-analysis was conducted with the aim to summarize all available evidence. MATERIALS AND METHODS: A literature search was performed using MEDLINE and EMBASE databases from inception to June 2016...
July 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28719357/vitamin-d-receptor-bsmi-polymorphism-may-be-associated-with-an-decreased-osteoporosis-risk-in-south-china
#14
M An, X-B Song, X-Y Chen
Although many epidemiology studies have evaluated the correlation between vitamin D receptor (VDR) BsmI polymorphism and osteoporosis, the current results remain inconclusive. This meta-analysis updated and reevaluated the possible association between VDR BsmI polymorphism and osteoporosis in Chinese populations. Studies were identified using PubMed and Chinese databases through December 2016. The associations were assessed with pooled odds ratios (ORs) and 95% confidence intervals (CIs). A total of nine studies with 688 osteoporosis cases and 730 controls were included in this meta-analysis...
May 20, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28695555/adherence-to-osteoporosis-pharmacotherapy-one-year-after-osteoporotic-fracture-a-swiss-trauma-center-secondary-prevention-project
#15
Sabrina Morell, Christoph Hemmeler, Felix Amsler, Thomas Gross
AIMS OF THE STUDY: According to current evidence, one out of ten fracture patients with osteoporosis does not sustain another fracture if he or she is on adequate medication. However, epidemiological surveys show that only about 15 to 30% of affected patients avail themselves of the treatments. This cohort study investigated how many fracture patients with a recommendation for antiosteoporotic therapy effectively received treatment and the possible reasons why the treatment was not implemented...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28690091/-paget-s-disease-of-bone-diagnostic-and-therapeutic-updates
#16
R Alaya, Z Alaya, M Nang, E Bouajina
Paget's disease of bone is the second most common metabolic bone disease after osteoporosis. Its pathogenesis is not yet clearly understood. Geographic distribution and epidemiological variations suggest a role of genetic and environmental factors in its pathophysiology. The frequency of the Paget's disease of bone increases with age. Its discovery can be fortuitous. Prognosis mainly depends on the occurrence of complications involving bones and joints, neurological, cardiovascular or metabolic systems. Treatment of symptomatic forms currently relies on bisphosphonates that have transformed its prognosis...
July 6, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28689879/nonstandard-lumbar-region-in-predicting-fracture-risk
#17
Dima Alajlouni, Dana Bliuc, Thach Tran, Nicholas Pocock, Tuan V Nguyen, John A Eisman, Jacqueline R Center
Femoral neck (FN) bone mineral density (BMD) is the most commonly used skeletal site to estimate fracture risk. The role of lumbar spine (LS) BMD in fracture risk prediction is less clear due to osteophytes that spuriously increase LS BMD, particularly at lower levels. The aim of this study was to compare fracture predictive ability of upper L1-L2 BMD with standard L2-L4 BMD and assess whether the addition of either LS site could improve fracture prediction over FN BMD. This study comprised a prospective cohort of 3016 women and men over 60 yr from the Dubbo Osteoporosis Epidemiology Study followed up for occurrence of minimal trauma fractures from 1989 to 2014...
July 6, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28674727/cellular-and-molecular-mechanisms-of-alcohol-induced-osteopenia
#18
REVIEW
Zhenhua Luo, Yao Liu, Yitong Liu, Hui Chen, Songtao Shi, Yi Liu
Alcoholic beverages are widely consumed, resulting in a staggering economic cost in different social and cultural settings. Types of alcohol consumption vary from light occasional to heavy, binge drinking, and chronic alcohol abuse at all ages. In general, heavy alcohol consumption is widely recognized as a major epidemiological risk factor for chronic diseases and is detrimental to many organs and tissues, including bones. Indeed, recent findings demonstrate that alcohol has a dose-dependent toxic effect in promoting imbalanced bone remodeling...
July 3, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28633866/tea-consumption-may-decrease-the-risk-of-osteoporosis-an-updated-meta-analysis-of-observational-studies
#19
REVIEW
Ming Guo, Hua Qu, Lin Xu, Da-Zhuo Shi
Several epidemiological investigations have evaluated the correlation between tea consumption and risk of osteoporosis, but the results are inconsistent. Therefore, we conducted an updated meta-analysis of observational studies to assess this association. We searched for all relevant studies including cohort, cross-sectional, and case-control studies published from database inception to July 15, 2016, using MEDLINE EMBASE, and Cochrane Library. Polled odds ratios (ORs) were calculated using the random-effect model...
June 2017: Nutrition Research
https://www.readbyqxmd.com/read/28631706/-osteoporosis-current-state-of-the-art
#20
REVIEW
A F Verbovoy, A V Pashentseva, L A Sharonova
As of now, osteoporosis (OP) is one of the most important sociomedical problems because of its high prevalence and resultant disability, as well as significant mortality attributable to complications. The current strategy for providing care for patients of OP is its early diagnosis, by determining the high risk of fractures, and early pathogenetic treatment. The article gives an update on the epidemiology, risk factors, diagnosis, and treatment of OP.
2017: Terapevticheskiĭ Arkhiv
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