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osteoporosis epidemiology

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https://www.readbyqxmd.com/read/29738949/associations-of-urinary-polycyclic-aromatic-hydrocarbons-with-bone-mass-density-and-osteoporosis-in-u-s-adults-nhanes-2005-2010
#1
Jing Guo, Yun Huang, Suchen Bian, Chuning Zhao, Yumin Jin, Dongdong Yu, Xinkai Wu, Dan Zhang, Weiming Cao, Fangyuan Jing, Guangdi Chen
Polycyclic aromatic hydrocarbons (PAHs) are environmental endocrine disruptors, which may modify the bone mineralization. However, epidemiological evidences on this issue were scant. We aimed to investigate the associations of PAHs with bone mass density (BMD) and osteoporosis based on a nationally-representative sample from general U.S. POPULATION: Data utilized were extracted from the 2005-2010 National Health and Nutrition Examination Survey (NHANES). Nine urinary PAHs (U-PAHs) metabolites were measured as exposure biomarkers...
May 5, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29738833/emerging-concepts-in-the-epidemiology-pathophysiology-and-clinical-care-of-postmenopausal-osteoporosis
#2
REVIEW
Daria Lizneva, Tony Yuen, Li Sun, Se-Min Kim, Ihor Atabiekov, Lubna Bashir Munshi, Maria New, Mone Zaidi
Bone loss in women accelerates during perimenopause, and continues into old age. To-date, there has been little progress made in stratifying fracture risk in premenopausal and early postmenopausal women. Epidemiologic data suggests that changes in serum FSH could predict decrements in bone mass during peri- and postmenopause. In bone, FSH interacts with immune receptor complexes, increases the expression of receptor activator of nuclear factor kappa B (RANK), and stimulates osteoclast formation by releasing osteoclastogenic cytokines...
May 5, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29694545/association-of-severity-of-coronary-lesions-with-bone-mineral-density-in-postmenopausal-women
#3
Rui Xu, Xin-Chun Cheng, Yuan Zhang, Hong-Mei Lai, Hong-Ni Yang
BACKGROUND: Coronary artery disease (CAD) and osteoporosis (OP) are common diseases in postmenopausal women. In both cross-sectional and longitudinal epidemiologic studies, low bone mass has been related to increased frequency of CAD. However, available data on the relationship between bone mineral density (BMD) and severity of coronary lesions is limited. OBJECTIVE: To investigate association between the BMD and severity of coronary lesions assessed by Gensini score in postmenopausal women...
March 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29623209/concurrent-primary-hyperparathyroidism-and-pheochromocytoma-in-a-chinese-lady-with-neurofibromatosis-type-1
#4
Cheuk-Lik Wong, Chun-Kit Fok, Vicki Ho-Kee Tam
We report a case of elderly Chinese lady with neurofibromatosis type-1 presenting with longstanding palpitation, paroxysmal hypertension and osteoporosis. Biochemical testing showed mild hypercalcaemia with non-suppressed parathyroid hormone level suggestive of primary hyperparathyroidism, and mildly elevated urinary fractionated normetanephrine and plasma-free normetanephrine pointing to a catecholamine-secreting pheochromocytoma/paraganglioma. Further scintigraphic investigation revealed evidence of a solitary parathyroid adenoma causing primary hyperparathyroidism and a left pheochromocytoma...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29595401/epidemiological-profile-of-thoracolumbar-fracture-tlf-over-a-period-of-10-years-in-tianjin-china
#5
Bo Li, Chao Sun, Chenxi Zhao, Xue Yao, Yan Zhang, Huiquan Duan, Jian Hao, Xing Guo, Baoyou Fan, Guangzhi Ning, Shiqing Feng
CONTEXT/OBJECTIVE: The objective of the research was to illustrate the epidemiology profile of thoracolumbar fracture (TLF) in Tianjin Medical University General Hospital, China, from 2006-2015. DESIGN: Hospital-based retrospective study. SETTING: Tianjin Medical University General Hospital. METHODS: Medical records of inpatient patients with TLF from 1 January 2006 to December 2015 were collected. Detailed information on epidemiological characters were analyzed based on the medical records suffering from TLF from T11-L2 level, including incidence, age and sex, marital, occupation, etiology and fracture type, types of injuries...
March 29, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29593198/associations-between-intake-of-dietary-fermented-soy-food-and-concentrations-of-inflammatory-markers-a-cross-sectional-study-in-japanese-workers
#6
Xiaolin Yang, Mariko Nakamoto, Emi Shuto, Akiko Hata, Nanako Aki, Yosuke Shikama, Yukiko Bando, Takako Ichihara, Takako Minamigawa, Yumi Kuwamura, Ayako Tamura, Hirokazu Uemura, Kokichi Arisawa, Makoto Funaki, Tohru Sakai
Epidemiological investigations have shown that consumption of soybeans or soy foods reduces the risk of the development of cardiovascular disease, cancer and osteoporosis. The aim of this study was to determine the associations between different soy foods and inflammatory markers, including high-sensitivity C-reactive protein (hs-CRP), interleukin (IL)-6, and IL-18, in Japanese workers. The cross-sectional study included 1,426 Japanese workers (1,053 men and 373 women) aged 20 to 64 years. Intake of 12 soy foods was estimated by a validated food frequency questionnaire...
2018: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/29564300/review-of-epidemiology-diagnosis-and-treatment-of-osteosarcopenia-in-korea
#7
REVIEW
Jun-Il Yoo, Yong-Chan Ha
Sarcopenia was listed in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) as M62.84, on October 1, 2016. Sarcopenia is primarily associated with metabolic diseases, such as diabetes, obesity, and cachexia, as well as chronic renal failure, congestive heart failure, and chronic obstructive pulmonary disease. Sarcopenia is also significantly associated with osteoporosis in elderly populations and the combined disease is defined as osteosarcopenia. Several studies have confirmed that sarcopenia and osteoporosis (osteosarcopenia) share common risk factors and biological pathways...
February 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29516129/prevalence-of-chronic-hypoparathyroidism-in-a-mediterranean-region-as-estimated-by-the-analysis-of-anonymous-healthcare-database
#8
Luisella Cianferotti, Simone Parri, Giorgio Gronchi, Gemma Marcucci, Cristiana Cipriani, Jessica Pepe, Marco Raglianti, Salvatore Minisola, Maria Luisa Brandi
Epidemiological data on prevalence and incidence of chronic hypoparathyroidism are still scarce. This study aimed to establish prevalence of chronic hypoparathyroidism and incidence of surgical hypoparathyroidism using the analysis of electronic anonymous public health care database. Data referred to a 5-year period (2009-2013, Region of Tuscany, Italy, as a sample representative of the whole Mediterranean/European population, estimated mean population: 3,750,000 inhabitants) were retrieved by the analysis of pharmaceutical distribution dataset, containing data related to drugs reimbursed by public health system, hospital discharge and procedures codes, and ICD9 exemption codes for chronic diseases...
March 8, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29508640/the-use-of-selective-estrogen-receptor-modulators-on-bone-health-in-men
#9
Sok Kuan Wong, Nur-Vaizura Mohamad, Putri Ayu Jayusman, Ahmad Nazrun Shuid, Soelaiman Ima-Nirwana, Kok-Yong Chin
Selective estrogen receptor modulators (SERMs) represent a class of drugs that act as agonist or antagonist for estrogen receptor in a tissue-specific manner. The SERMs drugs are initially used for the prevention and treatment of osteoporosis in postmenopausal women. Bone health in prostate cancer patients has become a significant concern, whereby patients undergo androgen deprivation therapy is often associated with deleterious effects on bone. Previous preclinical and epidemiological findings showed that estrogens play a dominant role in improving bone health as compared to testosterone in men...
March 6, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29502187/epidemiology-and-correlates-of-osteoporotic-fractures-among-type-2-diabetic-patients
#10
Inbal Goldshtein, Allison Martin Nguyen, Anne E dePapp, Sofia Ish-Shalom, Julie M Chandler, Gabriel Chodick, Varda Shalev
This study analyzed data on 87,224 osteoporotic patients with up to 18 years of computerized medical history. Patients with osteoporosis and type 2 diabetes had higher bone density yet more fractures than non-diabetic osteoporotic patients. Fracture incidence among the diabetic patients was associated with retinopathy and cardiovascular disease, but not with diabetes duration. PURPOSE: Little is known about the association between type 2 diabetes mellitus (T2DM) and fragility fractures or the mechanism(s) involved...
March 3, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29494336/telomere-biology-and-age-related-diseases
#11
REVIEW
Markus Herrmann, Irene Pusceddu, Winfried März, Wolfgang Herrmann
Telomeres are the protective end caps of chromosomes and shorten with every cell division. Telomere length has been proposed as a biomarker of biological age and a risk factor for age-related diseases. Epidemiologic studies show an association between leukocyte telomere length (LTL) and mortality. There is solid evidence that links LTL with cardiovascular disease. Short telomeres promote atherosclerosis and impair the repair of vascular lesions. Alzheimer's disease patients have also a reduced LTL. Telomeres measured in tumor tissue from breast, colon and prostate are shorter than in healthy tissue from the same organ and the same patient...
March 1, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29427505/does-the-association-of-comorbidity-with-1-year-mortality-after-hip-fracture-differ-according-to-gender-the-norwegian-epidemiologic-osteoporosis-studies-norepos
#12
Brit Solvor L Riska, Lisa Forsén, Tone K Omsland, Anne Johanne Søgaard, Haakon E Meyer, Kristin Holvik
BACKGROUND/OBJECTIVES: Excess mortality after hip fracture is higher in men than in women. The objective was to study whether comorbidity differs in men and women with hip fracture and to what degree differences in comorbidity according to gender may explain the higher excess mortality in men. DESIGN: Population-based matched cohort covering the population aged 50 and older in Norway. SETTING: Specialist healthcare (individuals with hip fracture) and general population (controls)...
March 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29383389/gout-as-a-risk-factor-for-osteoporosis-epidemiologic-evidence-from-a-population-based-longitudinal-study-involving-108-060-individuals
#13
V C Kok, J-T Horng, M N Wang, Z-Y Chen, J-T Kuo, G-D Hung
Is gout a risk factor for future osteoporosis? This large population-based study comprising two matched groups of individuals with and without gout demonstrates that patients with gout have a 20% increase in the risk of developing osteoporosis in future through an 8-year follow-up. INTRODUCTION: To examine if gout is associated with an increased risk of osteoporosis. METHODS: We conducted a nationwide population-based retrospective matched-cohort study. Two matched cohorts (n = 36,458 with gout and 71,602 without gout) assembled and recruited from the Longitudinal Health Insurance Dataset containing 1 million subjects...
April 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29378534/vertebral-fractures-among-breast-cancer-survivors-in-china-a-cross-sectional-study-of-prevalence-and-health-services-gaps
#14
Evelyn Hsieh, Qin Wang, Renzhi Zhang, Xin Niu, Weibo Xia, Liana Fraenkel, Karl L Insogna, Jing Li, Jennifer S Smith, Chunwu Zhou, You-Lin Qiao, Pin Zhang
BACKGROUND: Breast cancer survivors are at high risk for fracture due to cancer treatment-induced bone loss, however, data is scarce regarding the scope of this problem from an epidemiologic and health services perspective among Chinese women with breast cancer. METHODS: We designed a cross-sectional study comparing prevalence of vertebral fractures among age- and BMI-matched women from two cohorts. Women in the Breast Cancer Survivors cohort were enrolled from a large cancer hospital in Beijing...
January 30, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29372537/sex-and-management-of-rheumatoid-arthritis
#15
REVIEW
Ennio Giulio Favalli, Martina Biggioggero, Chiara Crotti, Andrea Becciolini, Maria Gabriella Raimondo, Pier Luigi Meroni
Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease more common in women than men (3:1). Although sex-based differences may play a complex role in promoting an autoimmune dysfunction, to date the comprehensive knowledge of the link between sex and RA is still partially lacking. Furthermore, males and females have been demonstrated to differently deal with their chronic pathologies, modifying the perceived sex-based burden of disease. Gender medicine is a newly approach focusing on the impact of gender differences on human physiology, pathophysiology, and clinical features of diseases, analyzing the complex interrelation and integration of sex and psychological and cultural behavior...
January 26, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29347932/epidemiology-of-arthritis-chronic-back-pain-gout-osteoporosis-spondyloarthropathies-and-rheumatoid-arthritis-among-1-5-million-patients-in-australian-general-practice-nps-medicinewise-medicineinsight-dataset
#16
David Alejandro González-Chica, Simon Vanlint, Elizabeth Hoon, Nigel Stocks
BACKGROUND: Previous estimates for the prevalence of musculoskeletal conditions (MSK) and chronic pain in Australia have been based on self-report. We aimed to determine the prevalence and distribution of arthritis, chronic back pain, gout, osteoporosis, spondyloarthropathies and rheumatoid arthritis and current consultations for chronic pain among adults attending Australian general practice, and describe their distribution according to sociodemographic characteristics and presence of co-morbidities...
January 18, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29344692/the-epidemiology-of-wrist-fractures-in-older-men-the-osteoporotic-fractures-in-men-mros-study
#17
N C Wright, E R Hooker, C M Nielson, K E Ensrud, S L Harrison, E S Orwoll, E Barrett-Connor
There is limited wrist fracture information on men. Our goal was to calculate frequency and identify risk factors for wrist fracture in the Osteoporotic Fractures in Men (MrOS) study. We confirmed that fracture history and certain medications are predictors, and identified novel predictors including markers of kidney function and physical performance. INTRODUCTION: To calculate the incidence of wrist fractures and their risk factors in older community-dwelling men from the US Osteoporotic Fractures in Men (MrOS) study...
April 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29328898/idiopathic-hypercalciuria-can-we-prevent-stones-and-protect-bones
#18
REVIEW
Laura E Ryan, Steven W Ing
Idiopathic hypercalciuria increases the risk of urinary stones and osteoporosis. The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, causes, epidemiology, laboratory evaluation, and potential treatments.
January 2018: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29285942/-non-alcoholic-fatty-liver-disease-as-a-component-of-the-metabolic-syndrome-and-its-causal-correlations-with-other-extrahepatic-diseases
#19
REVIEW
Tamás Halmos, Ilona Suba
Non-alcoholic fatty liver disease is the most common non-infectious chronic liver-disease in our age, and is a spectrum of all the diseases associated with increased fat accumulation in the hepatocytes. Its development is promoted by sedentary life-style, over-feeding, and certain genetic predisposition. Prevalence in the adult population, even in Hungary is ~30%. In a part of cases, this disease may pass into non-alcoholic steatohepatitis, later into fibrosis, rarely into primary hepatocellular cancer. Fatty liver is closely and bidirectionally related to the metabolic syndrome and type 2 diabetes, and nowadays there is a general consensus that fatty liver is the hepatic manifestation of the metabolic sycndrome...
December 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29259852/epidemiology-diagnosis-and-treatment-of-wilson-s-disease
#20
REVIEW
Jing Liu, Jing Luan, Xiaoyan Zhou, Yazhou Cui, Jinxiang Han
Wilson's disease (WD) is an autosomal recessive disease caused by a mutation of the ATP7B gene, resulting in abnormal copper metabolism. The major clinical features of WD include liver disease, neurological disorders, K-F rings, and osteoporosis. The prevalence of WD in China is higher than that in Western countries. Early diagnosis and lifelong treatment will lead to better outcomes. Drugs such as sodium dimercaptosuccinate (Na-DMPS), Zn, and Gandou Decoction can be used to treat WD. Some studies have shown that the combination of traditional Chinese medicine and Western medicine is the best approach to treating WD...
November 2017: Intractable & Rare Diseases Research
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