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https://www.readbyqxmd.com/read/29136193/early-first-trimester-uteroplacental-flow-and-the-progressive-disintegration-of-spiral-artery-plugs-new-insights-from-contrast-enhanced-ultrasound-and-tissue-histopathology
#1
V H J Roberts, T K Morgan, P Bednarek, M Morita, G J Burton, J O Lo, A E Frias
STUDY QUESTION: Does the use of a vascular contrast agent facilitate earlier detection of maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy? SUMMARY ANSWER: Microvascular filling of the IVS was demonstrated by contrast-enhanced ultrasound from 6 weeks of gestation onwards, earlier than previously believed. WHAT IS KNOWN ALREADY: During placental establishment and remodeling of maternal spiral arteries, endovascular trophoblast cells invade and accumulate in the lumen of these vessels to form 'trophoblast plugs'...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29128439/robotic-splenectomy-for-isolated-splenic-recurrence-of-endometrial-adenocarcinoma
#2
Valerio Gallotta, Marco D'Indinosante, Camilla Nero, Maria Teresa Giudice, Carmine Conte, Claudio Lodoli, Gian Franco Zannoni, Anna Fagotti, Giovanni Scambia
OBJECTIVES: We present a rare case of an isolated intraparenchymal splenic metastasis of endometrial cancer managed with robotic-assisted surgery. METHODS: A 55-year-old patient with a history of endometrial cancer was found to have a splenic lesion during her follow-up exams. She underwent surgical staging (total hysterectomy, bilateral salpingo-oopherectomy, pelvic lymphadenectomy and peritoneal washing) in 2014 and the final pathologic findings showed an endometrioid endometrial adenocarcinoma, FIGO Stage IB G2...
November 8, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29121880/comparison-of-different-therapeutic-strategies-for-complete-hydatidiform-mole-in-women-at-least-40%C3%A2-years-old-a-retrospective-cohort-study
#3
Peng Zhao, Qinqing Chen, Weiguo Lu
BACKGROUND: There are three main therapeutic strategies, namely expectant management (dilation and curettage only), prophylactic chemotherapy and prophylactic total hysterectomy for treating older women with complete hydatidiform mole (CHM). However, the scientific community has so far, not unanimously accepted the above-mentioned methods. The objective of this study was to evaluate the effectiveness of these therapeutic strategies in preventing post-molar gestational trophoblastic neoplasia (GTN) pertaining to patients with CHM who were at least 40 years old...
November 9, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29119546/a-systematic-review-of-ectopic-pregnancy-after-hysterectomy
#4
REVIEW
Emily X Shao, Kendra Hopper, Matthew McKnoulty, Alka Kothari
BACKGROUND: An ectopic pregnancy after hysterectomy is a rare but potentially life-threatening event. Women with this condition might not be appropriately investigated, resulting in delays in diagnosis and treatment. OBJECTIVES: To characterize cases of ectopic pregnancy occurring after hysterectomy. SEARCH STRATEGY: PubMed, Embase, Scopus, and Web of Science were searched using the terms "pregnancy, abdominal" or "pregnancy, tubal" or "pregnancy, ectopic" and "hysterectomy" or "post-hysterectomy" or "post hysterectomy...
November 9, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29103241/unexpected-significant-uterine-pathological-findings-at-vaginal-hysterectomy-despite-unremarkable-preoperative-workup
#5
Yossi Mizrachi, Samer Tannus, Jacob Bar, Ron Sagiv, Tally Levy, Alexander Condrea, Shimon Ginath
BACKGROUND: Several studies have addressed the issue of undetected uterine pathology in women undergoing hysterectomy for pelvic organ prolapse (POP). However, these studies differ largely with respect to the incidence of malignancy found, study population, and preoperative evaluation. OBJECTIVES: To assess the risk of unexpected pre-malignant and malignant uterine pathological findings after vaginal hysterectomy for POP repair, in a single medical center in Israel...
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29102507/occurrence-of-chronic-pelvic-pain-abnormal-uterine-bleeding-and-hysterectomy-post-procedure-among-women-who-have-undergone-female-sterilization-procedures-a-retrospective-claims-analysis-of-commercially-insured-women-in-the-us
#6
Patricia I Carney, Jianying Yao, Jay Lin, Amy Law
STUDY OBJECTIVE: To evaluate the frequency of chronic pelvic pain (CPP), abnormal uterine bleeding (AUB), and hysterectomy following hysteroscopic (HS) and laparoscopic (LS) sterilization in the US DESIGN: Retrospective cohort study (Canadian Task Force II-2) SETTING: Commercially-insured women PATIENTS: Women (18-49) with claims for HS or LS (1/1/2010-12/31/2012) were identified from the MarketScan Commercial database. Women were required to have 6 months of continuous coverage prior to (baseline) and 24 months after (follow-up) the procedure date...
November 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29067758/scoring-model-to-predict-massive-post-partum-bleeding-in-pregnancies-with-placenta-previa-a-retrospective-cohort-study
#7
Ji Yeon Lee, Eun Hee Ahn, Sukho Kang, Myung Jin Moon, Sang Hee Jung, Sung Woon Chang, Hee Young Cho
AIM: We aimed to identify factors associated with massive post-partum bleeding in pregnancies with placenta previa and to establish a scoring model to predict post-partum severe bleeding. METHODS: A retrospective cohort study was performed in 506 healthy singleton pregnancies with placenta previa from 2006 to 2016. Cases with intraoperative blood loss (≥2000 mL), packed red blood cells transfusion (≥4), uterine artery embolization, or hysterectomy were defined as massive bleeding...
October 25, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29067679/maternal-morbidity-after-implementation-of-a-postpartum-hemorrhage-protocol-including-use-of-misoprostol
#8
Ricardo Savirón-Cornudella, Luis M Esteban, Ramiro Laborda-Gotor, Belén Rodríguez-Solanilla, Bremen De Mucio, Gerardo Sanz, Sergio Castán-Mateo
OBJECTIVE: To compare maternal morbidity before and after implementation of a postpartum hemorrhage (PPH) protocol that included misoprostol. METHODS: A retrospective analysis was performed using data from 34 631 deliveries recorded at a Spanish hospital between January 1, 2007, and December 31, 2014. The PPH protocol was implemented in 2009 and included use of misoprostol and the Bakri balloon. RESULTS: The pre-implementation and post-implementation groups comprised 9394 and 25 237 women, respectively...
October 25, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29052067/concomitant-open-ventral-hernia-repair-what-is-the-financial-impact-of-performing-open-ventral-hernia-with-other-abdominal-procedures-concomitantly
#9
Vashisht Madabhushi, Margaret A Plymale, John Scott Roth, Sara Johnson, Alex Wade, Daniel L Davenport
BACKGROUND: Open ventral hernia repair (VHR) is often performed in conjunction with other abdominal procedures. Clinical outcomes and financial implications of VHR are becoming better understood; however, financial implications of concomitant VHR during other abdominal procedures are unknown. This study aimed to evaluate the financial implications of adding VHR to open abdominal procedures. METHODS: This IRB-approved study retrospectively reviewed hospital costs to 180-day post-discharge of standalone VHRs, isolated open abdominal surgeries (bowel resection or stoma closure, removal of infected mesh, hysterectomy or oophorectomy, panniculectomy or abdominoplasty, open appendectomy or cholecystectomy), performed at our institution from October 1, 2011 to September 30, 2014...
October 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29048746/long-term-occurrence-of-secondary-compartment-pelvic-organ-prolapse-after-open-mesh-sacrocolpopexy-for-symptomatic-prolapse
#10
Connie Wang, Alana L Christie, Philippe E Zimmern
AIMS: To report on the long-term occurrence of secondary compartment pelvic organ prolapse (POP) after open mesh sacrocolpopexy (MSC). METHODS: A prospectively maintained, IRB-approved database of non-neurogenic women with symptomatic triple compartment POP who underwent open MSC between 1999 and 2011 and had a 1-year minimum follow-up was reviewed. Length of follow-up was categorized as: intermediate (1-3 yr), late (3-5 yr), and very late (>5 yr). Demographic data, history of POP repairs, exam with Baden-Walker grading, validated questionnaires (Urogenital Distress Inventory short form [UDI-6], QoL), and outcomes at each follow-up visit were recorded...
October 19, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29040564/n-cadherin-identifies-human-endometrial-epithelial-progenitor-cells-by-in-vitro-stem-cell-assays
#11
Hong P T Nguyen, L Xiao, James A Deane, Ker-Sin Tan, Fiona L Cousins, Hirotaka Masuda, Carl N Sprung, Anna Rosamilia, Caroline E Gargett
STUDY QUESTION: Is there a specific surface marker that identifies human endometrial epithelial progenitor cells with adult stem cell activity using in vitro assays? SUMMARY ANSWER: N-cadherin isolates clonogenic, self-renewing human endometrial epithelial progenitor cells with high proliferative potential that differentiate into cytokeratin+ gland-like structures in vitro and identifies their location in some cells of gland profiles predominantly in basalis endometrium adjacent to the myometrium...
November 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29039055/treatment-patterns-complications-and-health-care-utilization-among-endometriosis-patients-undergoing-a-laparoscopy-or-a-hysterectomy-a-retrospective-claims-analysis
#12
Eric S Surrey, Ahmed M Soliman, Hongbo Yang, Ella Xiaoyan Du, Bowdoin Su
INTRODUCTION: Hysterectomy and laparoscopy are common surgical procedures used for the treatment of endometriosis. This study compares outcomes for women who received either procedure within the first year post initial surgery. METHODS: The study used data from the Truven Health MarketScan claims databases from 2004 to 2013 to identify women aged 18-49 years who received an endometriosis-related laparoscopy or hysterectomy. Patients were excluded if they did not have continuous insurance coverage from 1 year before through 1 year after their endometriosis-related procedure, if they were diagnosed with uterine fibroids prior to or on the date of surgery (i...
October 16, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29038834/the-treatment-of-post-hysterectomy-vaginal-vault-prolapse-a-systematic-review-and-meta-analysis
#13
REVIEW
Anne-Lotte W M Coolen, Bich Ngoc Bui, Viviane Dietz, Rui Wang, Aafke P A van Montfoort, Ben Willem J Mol, Jan-Paul W R Roovers, Marlies Y Bongers
INTRODUCTION AND HYPOTHESIS: The treatment of post-hysterectomy vaginal vault prolapse (VVP) has been investigated in several randomized clinical trials (RCTs), but a systematic review of the topic is still lacking. The aim of this study is to compare the effectiveness of treatments for VVP. METHODS: We performed a systematic review and meta-analysis of the literature on the treatment of VVP found in PubMed and Embase. Reference lists of identified relevant articles were checked for additional articles...
October 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29036173/pre-treatment-with-gnrha-or-ulipristal-acetate-prior-to-laparoscopic-and-laparotomic-myomectomy-a-systematic-review-and-meta-analysis
#14
REVIEW
Inge de Milliano, Moniek Twisk, Johannes C Ket, Judith A Huirne, Wouter J Hehenkamp
BACKGROUND: Myomectomy has potential risks of complications. To reduce these risks, medical pre-treatment can be applied to reduce fibroid size and thereby potentially decrease intra-operative blood loss, the need for blood transfusion and emergency hysterectomy. The aim of this systematic review and meta-analysis is to study the effectiveness of medical pre-treatment with Gonadotropin-releasing hormone agonists (GnRHa) or ulipristal acetate prior to laparoscopic or laparotomic myomectomy on intra-operative and post-operative outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/29032253/laparoscopic-dissection-of-extensive-secondary-disseminated-peritoneal-leiomyomatosis-dpl
#15
Karicha Mairaing, Kuan-Gen Huang
STUDY OBJECTIVE: To demonstrate a minimal invasive surgical (MIS) technique for curative excision of extensive secondary disseminated peritoneal leiomyomatosis (DPL). SETTING: In MIS, the myoma has to be divided into small fragments for piecemeal retrieval through a small incision [1], a widely used technique is morcellation (confined or unconfined) [2]. Disseminated peritoneal leiomyomatosis (DPL) is a rare sequel following laparoscopic morcellation. Since this entity is rarely reported, this video demonstrates laparoscopic technique for safe removal of DPL post laparoscopic myomectomy and morcellation...
October 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29017137/ovarian-vein-thrombosis-after-total-laparoscopic-hysterectomy-with-unilateral-adnexectomy-a-case-report
#16
Samer Nikolaos Al-Αchmar, Sofoklis Stavrou, Athanasios Protopapas, Peter Drakakis, Panagiota Siemou, Ioannis Chatzipapas
INTRODUCTION: Ovarian vein thrombosis is a rare but potentially serious complication after surgical and gynecologic procedures such as oophorectomy and hysterectomy. The association of this event with laparoscopic hysterectomy in particular, is very rare. Only two cases have been described so far. PRESENTATION OF CASE: We present a case of ovarian vein thrombosis after laparoscopic hysterectomy in a 40-year-old with deep endometriosis and multiple intramural uterine myomas...
October 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28988767/could-lymphadenectomy-be-avoided-in-locally-advanced-cervical-cancer-patients-administered-preoperative-chemoradiation-a-large-scale-retrospective-study
#17
Gabriella Ferrandina, Mariagrazia Distefano, Floriana Mascilini, Valerio Gallotta, Vito Chiantera, Francesco Cosentino, Barbara Costantini, Alfredo Ercoli, Luigi Pedone Anchora, Francesco Fanfani, Alessandro Pasquale Margariti, Vincenzo Valentini, Giovanni Scambia
INTRODUCTION: To identify a subset of cervical cancer (CC) patients administered chemoradiation (CT/RT) plus radical surgery (RS), who can be spared lymphadenectomy, and complications. PATIENTS AND METHODS: 430 Stage IB2-IIB patients without LN involvement at imaging were accrued (March 1996-December 2015) at Gynecologic Oncology Unit of the Catholic University of Rome/Campobasso. CT/RT consisted of pelvic irradiation plus cisplatin based chemotherapy. Objective response was evaluated according to RECIST criteria; radical hysterectomy and pelvic ± aortic lymphadenectomy was attempted in patients achieving response or stable disease...
September 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28988211/menopausal-age-postmenopausal-hormone-therapy-and-incident-atrial-fibrillation
#18
Jorge A Wong, Kathryn M Rexrode, Roopinder K Sandhu, M Vinayaga Moorthy, David Conen, Christine M Albert
OBJECTIVE: Limited data exist on the association between menopause and atrial fibrillation (AF). We sought to examine the relationship between menopausal age, postmenopausal hormone therapy (PHT) use and incident AF. METHODS: The Women's Health Study (WHS) enrolled 39 876 female health professionals between 1992 and 1995. We prospectively examined 30 034 women in WHS using Cox proportional-hazard models. Participants were free of cardiovascular disease and AF at baseline and had not undergone hysterectomy without bilateral oophorectomy prior to menopause...
October 7, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28984096/preventative-effect-of-ketamine-on-post-surgical-hyperalgesia-induced-at-a-body-part-remote-from-the-surgical-site-a-randomized-controlled-trial
#19
Young-Eun Moon, Mi-Hyun Kim, Hyung-Mook Lee, Hyo-Min Yoon, Young-Jae Jeon
BACKGROUND: It is known that pain hypersensitivity can be induced at a body part remote from a surgical site (tertiary hyperalgesia), leading to patient discomfort. Nevertheless, no reported study to date has investigated methods to attenuate such tertiary hyperalgesia. Ketamine is known to modulate hyperalgesia induced by central sensitization. Thus, we investigated whether intraoperative administration of ketamine could decrease post-surgical tertiary hyperalgesia in patients undergoing a laparoscopic hysterectomy...
October 4, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28972301/peripartum-hysterectomy-an-economic-analysis-of-direct-health-care-costs-using-routinely-collected-data
#20
Felix Achana, Kate M Fleming, Laila J Tata, Alyshah Abdul Sultan, Stavros Petrou
OBJECTIVE: To estimate resource use and costs associated with peripartum hysterectomy for the English National Health Service. DESIGN/SETTING: Analysis of linked Clinical Practice Research Datalink and Hospital Episodes Statistics (CPRD-HES) data. POPULATION: Women undergoing peripartum hysterectomy between 1997 and 2013 and matched controls. METHODS: Inverse probability weighted generalised estimating equations were used to model the non-linear trend in healthcare service use and costs over time, accounting for missing data, adjusting for maternal age, body mass index, delivery year, smoking and socio-economic indicators...
October 3, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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