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https://www.readbyqxmd.com/read/29783250/-signifuing-resident-of-the-city-poltava-at-the-expense-of-signs-stroke-risk-factors-and-urgent-measures-according-to-medico-social-survey
#1
Anzhelina M Kryvchun, Nataliia V Lytvynenko, Viktoriia A Pinchuk, Galyna Ya Sylenko, Viktoriia M Gladka
OBJECTIVE: Introduction: The problem of cerebrovascular diseases and their most severe form - cerebral stroke is one of the most pressing problems in modern medicine due to the high level of lethality, significant disability of patients. The aim: To assess and increase the sign of residents of the city Poltava at the expense of signs of stroke, its risk factors for emergence and emergency measures for stroke. PATIENTS AND METHODS: Materials and methods: During the annual social event dedicated to the World Stroke Day, on October 27, 2017, a survey of 981 people in Poltava city was conducted by volunteer students and staff of the Department of Nervous Diseases with Neurosurgery and Medical Genetics of "Ukrainian Medical Stomatological Academy"...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782937/health-disparities-among-children-with-asthma-in-the-u-s-by-place-of-residence
#2
Patrick W Sullivan, Vahram Ghushchyan, Abhishek Kavati, Prakash Navaratnam, Howard S Friedman, B Ortiz
BACKGROUND: Children residing in poor-urban areas may have greater asthma morbidity. It is unclear if this is due to individual characteristics like race and ethnicity or place of residence. OBJECTIVE: Assess indicators of control and treatment by residence. METHODS: This was a cross-sectional analysis of children (aged 1-17) in the 2000-2014 Medical Expenditure Panel Survey (MEPS). Indicators of poor control included use of > 3 canisters of short-acting beta agonist (SABA) in 3 months, asthma attack, and Emergency Department (ED) or inpatient (IP) visit during the year...
May 18, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29782706/biological-stimulus-driven-assembly-disassembly-of-functional-nanoparticles-for-targeted-delivery-controlled-activation-and-bioelimination
#3
REVIEW
Xi Hu, Fangyuan Li, Shuying Wang, Fan Xia, Daishun Ling
Nanoassembly technology has emerged as a powerful tool for targeted drug delivery and provides a basis for fabricating medical theranostic nanosystems. However, it is extremely difficult to concentrate nanoparticles at tumor sites, and the poor target-to-background ratio undoubtedly obstructs the accurate diagnosis and effective therapy of cancerous tissues. Importantly, the addition of biological stimulus-responsive groups to nanoassembly systems can enable a biological stimulus-driven assembly-disassembly mutual switch or structural composition/conformation change, thereby amplifying the imaging signal and/or enhancing the therapeutic effect...
May 21, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29782482/trauma-patients-are-safe-to-fly-72-hours-after-tube-thoracostomy-removal
#4
David Zonies, Joel Elterman, Christopher Burns, Vincent Paul, John Oh, Jeremy Cannon
BACKGROUND: Current recommendations for safe air travel following traumatic pneumothorax are 2-3 weeks after radiographic resolution. These recommendations are based on several small observational studies and expert consensus which cite a theoretical risk of recurrence and hypoxia due to decreased oxygen tension at altitude. We sought to systematically study the timing of chest drain removal after traumatic pneumothorax and risk of recurrence in relation to air travel. METHODS: A retrospective cohort study of consecutively admitted patients who sustained a traumatic chest injury treated with tube thoracostomy over a 5-year period was undertaken...
May 18, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29782399/frozen-in-time-a-history-of-the-synthesis-of-nitrous-oxide-and-how-the-process-remained-unchanged-for-over-2-centuries
#5
Alexander Buslov, Matthew Carroll, Manisha S Desai
Three major factors have contributed to the unrivaled popularity of nitrous oxide (N2O) among anesthetists in the 20th century and beyond: its impressive safety profile, its affordability, and its rapid induction and emergence times. These 3 characteristics of N2O have been discussed and written about extensively throughout the medical literature. Nonetheless, the characteristic that contributed most to N2O's initial discovery-the elegance and simplicity of its synthesis-has received substantially less attention...
May 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29782353/implementing-best-practice-into-the-emergency-department-triage-process
#6
Luke Burgess, Kathryn Kynoch, Sonia Hines
BACKGROUND: Triage is the process by which emergency departments (EDs) sort patients presenting for medical treatment. The Australasian Triage Scale, validated to measure urgency, answers the question 'This patient should wait for medical assessment and treatment no longer than…' Multiple patients may present within short time frames, and some will have conditions that have outcomes directly related to timeliness of treatment such as stroke, sepsis and myocardial infarction. The safety of patients within the ED is thus directly related to the triage system...
May 17, 2018: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/29782290/-the-notion-of-chf-course-stability-is-it-acceptable-for-russian-practice
#7
I V Fomin, N Kraiem, D S Polyakov, N G Vinogradova, F Y Valikulova, A R Vaysberg, E V Shechrbinina
AIM: To evaluate preparedness of physicians in real clinical practice to strive for stabilizing the course of CHF by control of clinical and hemodynamic indexes both in prevention of admission for decompensated CHF and following discharge from the hospital. MATERIALS AND METHODS: The study included 750 CHF patients with any NYHA FC who were admitted in emergency for decompensated CHF. All patients with CHF were followed up for a year after discharge from the hospital...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29781972/human-trafficking-how-nurses-can-make-a-difference
#8
Meredith Scannell, Andrea E MacDonald, Amanda Berger, Nichole Boyer
Human trafficking is a human rights violation and a global health problem. Victims of human trafficking have medical and mental health sequelae requiring specific healthcare interventions. Healthcare professionals may be the initial contact that these victims make outside the world of trafficking. Healthcare professionals are key agents in the identification of human trafficking, which is essential in eliminating this public health problem. Unfortunately, healthcare professionals are not always able to detect signs of human trafficking...
April 2018: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/29781406/analysis-of-emergency-health-care-workforce-and-service-readiness-for-a-mass-casualty-event-in-the-republic-of-ireland
#9
Tener Goodwin Veenema, Fiona Boland, Declan Patton, Tom O'Connor, Zena Moore, Sarah Schneider-Firestone
OBJECTIVE: Ultimately, a country's capacity for a large-scale major emergency response will be directly related to the competence of its health care provider (HCP) workforce and communication between emergency responders and hospitals. The purpose of this study was to assess HCP preparedness and service readiness for a major emergency involving mass casualties (mass casualty event or MCE) in Ireland. METHODS: A cross-sectional study using a 53-item survey was administered to a purposive sample of emergency responders and HCPs in the Republic of Ireland...
May 21, 2018: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29781385/procalcitonin-guided-use-of-antibiotics-for-lower-respiratory-tract-infection
#10
David T Huang, Donald M Yealy, Michael R Filbin, Aaron M Brown, Chung-Chou H Chang, Yohei Doi, Michael W Donnino, Jonathan Fine, Michael J Fine, Michelle A Fischer, John M Holst, Peter C Hou, John A Kellum, Feras Khan, Michael C Kurz, Shahram Lotfipour, Frank LoVecchio, Octavia M Peck-Palmer, Francis Pike, Heather Prunty, Robert L Sherwin, Lauren Southerland, Thomas Terndrup, Lisa A Weissfeld, Jonathan Yabes, Derek C Angus
Background The effect of procalcitonin-guided use of antibiotics on treatment for suspected lower respiratory tract infection is unclear. Methods In 14 U.S. hospitals with high adherence to quality measures for the treatment of pneumonia, we provided guidance for clinicians about national clinical practice recommendations for the treatment of lower respiratory tract infections and the interpretation of procalcitonin assays. We then randomly assigned patients who presented to the emergency department with a suspected lower respiratory tract infection and for whom the treating physician was uncertain whether antibiotic therapy was indicated to one of two groups: the procalcitonin group, in which the treating clinicians were provided with real-time initial (and serial, if the patient was hospitalized) procalcitonin assay results and an antibiotic use guideline with graded recommendations based on four tiers of procalcitonin levels, or the usual-care group...
May 20, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29781384/how-to-uncover-sources-of-unwarranted-practice-variation-a-case-study-in-emergency-medicine
#11
Markus A Feufel
Forty years of statistical database analyses have demonstrated the existence of unwarranted practice variation in care delivery, that is, variations independent of medical need, evidence, or patient preference. Alas, little is known about the underlying mechanisms and thus finding interventions to reduce unwarranted variations remains difficult, hampering quality, equity, and efficiency of care. Whereas statistical analyses describe deviations from ideal patterns, ethnographically inspired analyses aim at understanding when, how, and why variations occur in practice...
May 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29781319/assessing-the-role-of-ranibizumab-in-improving-the-outcome-of-glaucoma-filtering-surgery-and-neovascular-glaucoma
#12
Andreas Katsanos, Kostantina Gorgoli, Dimitrios G Mikropoulos, Esther Arranz-Marquez, Georgios P Athanasopoulos, Miguel A Teus, Anastasios G P Konstas
Ranibizumab was the first anti-vascular endothelial growth factor (VEGF) agent approved for the treatment of neovascular age-related macular degeneration. The use of ranibizumab and other anti-VEGF medications in recent years has revolutionized the treatment of several sight-threatening retinal disorders. Emerging evidence has demonstrated that anti-VEGF treatment can offer advantages in the management of other ocular conditions where VEGFs play a key role: ocular scarring following glaucoma filtering surgery and neovascular glaucoma (NVG)...
May 19, 2018: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/29781108/an-exploratory-study-of-sectra-table-visualization-improves-the-effectiveness-of-emergency-bedside-echocardiography-training
#13
Di Shi, Joseph H Walline, Jihai Liu, Xuezhong Yu, Jun Xu, Priscilla P Song, Huadong Zhu, John M O'Donnell
OBJECTIVES: Echocardiography is an essential tool in emergency medicine, and its training is the most challenging of all types of bedside ultrasound (US) training. This study investigated the effectiveness of the Sectra Table (Sectra AB, Linköping, Sweden), an anatomy visualization and collaboration tool, in improving the quality of echocardiography training for emergency medicine physicians. METHODS: We conducted an exploratory prospective observational study from 2015 to 2017 and enrolled 66 trainees who participated in a 2...
May 21, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29781044/sleeve-gastrectomy-in-morbidly-obese-hiv-patients-focus-on-anti-retroviral-treatment-absorption-after-surgery
#14
Chloé Amouyal, Marion Buyse, Lea Lucas-Martini, Déborah Hirt, Laurent Genser, Adriana Torcivia, Jean-Luc Bouillot, Jean-Michel Oppert, Judith Aron-Wisnewsky
CONTEXT: Anti-retroviral therapy (ART) dramatically reduced AIDS development, thus enabling patients to live as long as the general population. New challenges have emerged particularly cardiometabolic diseases and weight gain, with some HIV patients seeking bariatric surgery (BS). However, BS outcomes during HIV remain poorly described, with scarce data on ART pharmacokinetic post-BS. OBJECTIVE: Describing sleeve gastrectomy (SG) results in HIV patients in terms of ART pharmacokinetic, HIV control, weight loss, and metabolic outcomes...
May 20, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29780899/perspectives-on-the-evolving-state-of-the-art-management-of-gastrointestinal-stromal-tumours
#15
REVIEW
Zoltan Szucs, Robin L Jones
Gastrointestinal stromal tumours (GISTs) represent a very exciting tumour entity for the medical oncologist. There has been extensive clinical and preclinical research dissecting the natural behaviour, molecular landscape and therapeutic responsiveness of this rare mesenchymal tumour. Various molecular subtypes of GIST have a differing prognostic and predictive relevance in the state of the art management of the disease. Emerging mature clinical trial data gathered over the last one and half decade provided substantial molecular profiling information in understanding the success and eventual failure of treatment...
2018: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29780802/exploring-the-potential-of-generative-adversarial-networks-for-synthesizing-radiological-images-of-the-spine-to-be-used-in-in-silico-trials
#16
Fabio Galbusera, Frank Niemeyer, Maike Seyfried, Tito Bassani, Gloria Casaroli, Annette Kienle, Hans-Joachim Wilke
In silico trials recently emerged as a disruptive technology, which may reduce the costs related to the development and marketing approval of novel medical technologies, as well as shortening their time-to-market. In these trials, virtual patients are recruited from a large database and their response to the therapy, such as the implantation of a medical device, is simulated by means of numerical models. In this work, we propose the use of generative adversarial networks to produce synthetic radiological images to be used in in silico trials...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29780721/type-b-aortic-dissection-new-perspectives
#17
REVIEW
Marc A A M Schepens
Background: Stanford type B aortic dissection is one of the aortic catastrophes with a high mortality and morbidity that needs immediate or delayed treatment, either surgically or endovascularly. This comprehensive review article addresses the current status of open, endovascular and hybrid treatment options for type B aortic dissections with the focus on new therapeutic perspectives. Methods: Evaluation of currently available evidence based on randomized and registry data and personal experience...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29780633/deep-learning-aided-decision-support-for-pulmonary-nodules-diagnosing-a-review
#18
REVIEW
Yixin Yang, Xiaoyi Feng, Wenhao Chi, Zhengyang Li, Wenzhe Duan, Haiping Liu, Wenhua Liang, Wei Wang, Ping Chen, Jianxing He, Bo Liu
Deep learning techniques have recently emerged as promising decision supporting approaches to automatically analyze medical images for different clinical diagnosing purposes. Diagnosing of pulmonary nodules by using computer-assisted diagnosing has received considerable theoretical, computational, and empirical research work, and considerable methods have been developed for detection and classification of pulmonary nodules on different formats of images including chest radiographs, computed tomography (CT), and positron emission tomography in the past five decades...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29779949/disease-heritability-inferred-from-familial-relationships-reported-in-medical-records
#19
Fernanda C G Polubriaginof, Rami Vanguri, Kayla Quinnies, Gillian M Belbin, Alexandre Yahi, Hojjat Salmasian, Tal Lorberbaum, Victor Nwankwo, Li Li, Mark M Shervey, Patricia Glowe, Iuliana Ionita-Laza, Mary Simmerling, George Hripcsak, Suzanne Bakken, David Goldstein, Krzysztof Kiryluk, Eimear E Kenny, Joel Dudley, David K Vawdrey, Nicholas P Tatonetti
Heritability is essential for understanding the biological causes of disease but requires laborious patient recruitment and phenotype ascertainment. Electronic health records (EHRs) passively capture a wide range of clinically relevant data and provide a resource for studying the heritability of traits that are not typically accessible. EHRs contain next-of-kin information collected via patient emergency contact forms, but until now, these data have gone unused in research. We mined emergency contact data at three academic medical centers and identified 7...
May 15, 2018: Cell
https://www.readbyqxmd.com/read/29779679/loperamide-abuse-cardiotoxicity-should-loperamide-still-be-an-over-the-counter-medication
#20
Amr Idris, Kenji Kaye
Loperamide is an over-the-counter anti-diarrheal medication that is inexpensive, easily accessible, and widely used. It is generally thought to be safe and effective without the potential for abuse. However, recent discovery of its ability to treat opioid withdrawal symptoms at high doses has led to not only its abuse, but also the need to recognize its cardiotoxicity due to the ability to prolong the QTc interval. We report a case of a 33 year old female with a history of opioid dependence who presented to the emergency department with acute onset shortness of breath and generalized weakness who was subsequently found to be in ventricular tachycardia...
May 18, 2018: American Journal of Emergency Medicine
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