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https://www.readbyqxmd.com/read/28078732/a-fleshy-growth-below-the-nail-plate-in-an-elderly-man
#1
Neetu Bhari, Vinod K Sharma, B Lal Jangid, Sudheer Arava, Anurag Srivastava
No abstract text is available yet for this article.
January 11, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28074340/clinical-significance-of-cathepsin-l-and-cathepsin-b-in-dilated-cardiomyopathy
#2
Siddharth Mehra, Manish Kumar, Mansi Manchanda, Ratnakar Singh, Bhaskar Thakur, Neha Rani, Sudheer Arava, Rajiv Narang, Dharamvir Singh Arya, Shyam S Chauhan
Dysregulated expression of lysosomal cysteine cathepsins is associated with adverse cardiac remodeling, a characteristic of several cardiovascular diseases. However, the information regarding the role of cysteine cathepsin L (CTSL) and cathepsin B (CTSB) in dilated cardiomyopathy (DCM) is limited. The present study was aimed to investigate the expression of CTSL and CTSB in animal model of doxorubicin (doxo)-induced cardiomyopathy as well as in peripheral blood samples of DCM patients. Cardiac tissue sections from doxo-treated and control rats were used to study the expression of CTSL and CTSB by enzyme assay and immunohistochemistry (IHC)...
January 10, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28035119/a-case-of-pseudorheumatism-with-submasseteric-abscess-and-hlh-in-a-patient-with-visceral-leishmaniasis-a-diagnostic-dilemma
#3
Prasan Kumar Panda, Srikant Mohta, S K Sharma, Animesh Ray, Sudheer Arava, Surabhi Vyas
No abstract text is available yet for this article.
October 2016: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28001059/transition-metal-dichalcogenide-atomic-layers-for-lithium-polysulfides-electrocatalysis
#4
Ganguli Babu, Nirul Masurkar, Hesham Al Salem, Leela Mohana Reddy Arava
Lithium-sulfur (Li-S) chemistry is projected to be one of the most promising for next-generation battery technology, and controlling the inherent "polysulfide shuttle" process has become a key research topic in the field. Regulating intermediary polysulfide dissolution by understanding the metamorphosis is essential for realizing stable and high-energy-density Li-S batteries. As of yet, a clear consensus on the basic surface/interfacial properties of the sulfur electrode has not been achieved, although the catalytic phenomenon has been shown to result in enhanced cell stability...
December 21, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27984385/conventional-transbronchial-needle-aspiration-versus-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-with-or-without-rapid-on-site-evaluation-for-the-diagnosis-of-sarcoidosis-a-randomized-controlled-trial
#5
Karan Madan, Ashesh Dhungana, Anant Mohan, Vijay Hadda, Deepali Jain, Sudheer Arava, Ravindra M Pandey, Gopi C Khilnani, Randeep Guleria
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as a standalone modality is superior to conventional TBNA (c-TBNA) for the diagnosis of sarcoidosis. However, the overall yield is not different if combined with endobronchial biopsy (EBB) and transbronchial lung biopsy (TBLB). The utility of rapid on-site evaluation (ROSE) in a comparative evaluation of EBUS-TBNA versus c-TBNA for the diagnosis of sarcoidosis has not been previously evaluated. METHODS: Eighty patients with suspected sarcoidosis were randomized 1:1:1:1 into 4 groups: c-TBNA without ROSE (TBNA-NR), c-TBNA with ROSE (TBNA-R), EBUS-TBNA without ROSE (EBUS-NR), and EBUS-TBNA with ROSE (EBUS-R)...
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27908229/localization-of-nuclear-encoded-mrnas-to-mitochondria-outer-surface
#6
REVIEW
A Golani-Armon, Y Arava
The diverse functions of mitochondria depend on hundreds of different proteins. The vast majority of these proteins is encoded in the nucleus, translated in the cytosol, and must be imported into the organelle. Import was shown to occur after complete synthesis of the protein, with the assistance of cytosolic chaperones that maintain it in an unfolded state and target it to the mitochondrial translocase of the outer membrane (TOM complex). Recent studies, however, identified many mRNAs encoding mitochondrial proteins near the outer membrane of mitochondria...
October 2016: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/27890991/pulmonary-alveolar-proteinosis-experience-from-a-tertiary-care-center-and-systematic-review-of-indian-literature
#7
Vijay Hadda, Pawan Tiwari, Karan Madan, Anant Mohan, Nishkarsh Gupta, Sachidanand Jee Bharti, Vinod Kumar, Rakesh Garg, Anjan Trikha, Deepali Jain, Sudheer Arava, Gopi C Khilnani, Randeep Guleria
BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by deposition of lipoproteinaceous material within alveoli, with a variable clinical course. Here, we report an experience of management of PAP at our center. A systematic review of previously reported cases from India is also included in the article. MATERIALS AND METHODS: This study included patients with primary PAP managed at our center from 2009 to 2015. Diagnosis of primary PAP was based on histopathologic diagnosis on bronchoalveolar lavage or transbronchial lung biopsy and absence of causes of secondary PAP...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27813078/bleeding-erythematous-papules-over-nose-in-a-middle-aged-man
#8
Neetu Bhari, Kanika Sahni, Sudheer Arava
No abstract text is available yet for this article.
November 4, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27797848/invasive-thymoma-presenting-as-classic-superior-vena-cava-syndrome-a-case-of-venous-spread-metastasis
#9
Prasan Kumar Panda, Naveet Wig, Sanjeev Kumar, Sudheer Arava
The approach to an intrinsic cause of superior vena cava syndrome (SVCS) is usually difficult but rewarding. We report a case of a middle-aged man who presented with progressive oedema of the upper half of the body, dyspnoea, cough and weight loss for a 1-year duration. He was a non-smoker without prior hospitalisation. Chest radiography showed right-sided pleural effusion with an apparent normal superior mediastinum. Contrast-enhanced CT of the chest revealed a right atrial mass extending and completely obliterating to superior vena cava...
October 26, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27788994/incessant-left-ventricular-tachycardia-of-unusual-etiology
#10
Praloy Chakraborty, H S Isser, Sudheer Arava, Kausik Mandal
Apart from Coronary artery disease, left ventricular tachycardia may result from cardiac sarcoidosis, left ventricular tumor, chagas disease and idiopathic left ventricular tachycardia. We report a rare case of incessant left ventricular tachycardia resulting from left dominant arrhythmogenic cardiomyopathy.
May 2016: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/27775120/high-temperature-electrical-energy-storage-advances-challenges-and-frontiers
#11
Xinrong Lin, Maryam Salari, Leela Mohana Reddy Arava, Pulickel M Ajayan, Mark W Grinstaff
With the ongoing global effort to reduce greenhouse gas emission and dependence on oil, electrical energy storage (EES) devices such as Li-ion batteries and supercapacitors have become ubiquitous. Today, EES devices are entering the broader energy use arena and playing key roles in energy storage, transfer, and delivery within, for example, electric vehicles, large-scale grid storage, and sensors located in harsh environmental conditions, where performance at temperatures greater than 25 °C are required. The safety and high temperature durability are as critical or more so than other essential characteristics (e...
October 24, 2016: Chemical Society Reviews
https://www.readbyqxmd.com/read/27768054/novel-rna-binding-proteins-isolation-by-the-rapid-methodology
#12
Nitzan Samra, Yoav Arava
RNA-binding proteins (RBPs) play important roles in every aspect of RNA metabolism and regulation. Their identification is a major challenge in modern biology. Only a few in vitro and in vivo methods enable the identification of RBPs associated with a particular target mRNA. However, their main limitations are the identification of RBPs in a non-cellular environment (in vitro) or the low efficiency isolation of RNA of interest (in vivo). An RNA-binding protein purification and identification (RaPID) methodology was designed to overcome these limitations in yeast and enable efficient isolation of proteins that are associated in vivo...
September 30, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27741281/high-ancient-genetic-diversity-of-human-lice-pediculus-humanus-from-israel-reveals-new-insights-into-the-origin-of-clade-b-lice
#13
Nadia Amanzougaghene, Kosta Y Mumcuoglu, Florence Fenollar, Shir Alfi, Gonca Yesilyurt, Didier Raoult, Oleg Mediannikov
The human head louse, Pediculus humanus capitis, is subdivided into several significantly divergent mitochondrial haplogroups, each with particular geographical distributions. Historically, they are among the oldest human parasites, representing an excellent marker for tracking older events in human evolutionary history. In this study, ancient DNA analysis using real-time polymerase chain reaction (qPCR), combined with conventional PCR, was applied to the remains of twenty-four ancient head lice and their eggs from the Roman period which were recovered from Israel...
2016: PloS One
https://www.readbyqxmd.com/read/27739273/chronic-tubulo-interstitial-pyelonephritis-with-retroperitoneal-fibrosis
#14
Manish Soneja, S Achintya, Neeraj Nischal, Piyush Ranjan, Surabhi Vyas, Sudheer Arava, S K Sharma
A large proportion of patients with retroperitoneal fibrosis (RPF) have been labelled as having idiopathic RPF historically. Recent reports of a subset of these patients having a fibro-inflammatory condition with characteristic histology and good response to therapy has helped in renewed understanding of an old disease. A 40 year old man presented with vague abdominal discomfort of 5 months duration. Ultrasound examination revealed soft tissue thickening with calcification over lower abdominal aorta. CT scan characterized the lesion as a retroperitoneal mass encasing the aorta with an associated lesion in upper pole of left kidney...
June 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27732001/synthesis-of-%C3%AE-amino-substituted-enones-by-addition-of-substituted-methyl-enones-to-sulfinimines-application-to-the-total-synthesis-of-alkaloids-lasubine-ii-and-241d-and-the-formal-total-synthesis-of-lasubine-i
#15
Arava Amaranadha Reddy, Polimera Obula Reddy, Kavirayani R Prasad
Addition of silyl enol ethers obtained from substituted methyl enones to chiral sulfinimines afforded the β-amino-substituted enones with excellent selectivity. Utility of the obtained N-sulfinyl β-amino ketones possessing α,β-unsaturation is exemplified in the total synthesis of the quinolizidine alkaloid natural products (-)-lasubine I, (+)-lasubine II, and substituted piperidine alkaloid (+)-241-D.
November 18, 2016: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/27535728/histoplasmosis-mimicking-non-hodgkin-lymphoma-in-a-40-year-old-man-with-aids
#16
Neetu Bhari, Piyush Pahadiya, Sudheer Arava, Somesh Gupta
In patients with acquired immunodeficiency syndrome (AIDS), advanced immunosuppression is associated with atypical presentation of dermatological conditions. Our patient presented with a single crusted plaque over the lower lip and large tender cervical lymphadenopathy. The enzyme-linked immunosorbent assay for human immunodeficiency virus was found to be positive, and his CD4+ lymphocyte cell count was 4 cells/mm(3) The presence of multiple histoplasma spores in the biopsies from the crusted plaque over lip and cervical lymph node helped in the confirmation of the diagnosis of histoplasmosis, and the patient showed significant improvement within two months of treatment with conventional injection amphotericin B initially followed by oral itraconazole...
August 17, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27530877/goltz-syndrome-a-rare-case-of-father-to-daughter-transmission
#17
Vishal Gupta, Himabindu Saginatham, Sudheer Arava, Gomathy Sethuraman
An 8-year-old girl presented to us with skin-coloured to yellowish soft compressible papules, intermixed with hypopigmented and hyperpigmented macules in a Blaschkoid pattern, and 'lobster-claw deformity' affecting her bilateral feet. Additional examination findings included short stature, facial asymmetry, low-set ears, hypodontia, enamel hypoplasia, tonsillar enlargement and spina-bifida occulta at S1-3 vertebral level. A diagnosis of Goltz syndrome was suspected clinically, which was confirmed on skin biopsy...
August 16, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27436967/mixed-finite-element-formulations-in-piezoelectricity-and-flexoelectricity
#18
Sheng Mao, Prashant K Purohit, Nikolaos Aravas
Flexoelectricity, the linear coupling of strain gradient and electric polarization, is inherently a size-dependent phenomenon. The energy storage function for a flexoelectric material depends not only on polarization and strain, but also strain-gradient. Thus, conventional finite-element methods formulated solely on displacement are inadequate to treat flexoelectric solids since gradients raise the order of the governing differential equations. Here, we introduce a computational framework based on a mixed formulation developed previously by one of the present authors and a colleague...
June 2016: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/27401289/-benificial-effects-of-aqueous-extract-of-stem-bark-of-terminalia-arjuna-roxb-an-ayurvedic-drug-in-experimental-pulmonary-hypertension
#19
Himanshu Meghwani, Pankaj Prabhakar, Soheb A Mohammed, Sandeep Seth, Milind P Hote, Sanjay K Banerjee, Sudheer Arava, Ruma Ray, Subir Kumar Maulik
ETHNOPHARMACOLOGICAL RELEVANCE: The stem bark of Terminalia arjuna (Roxb.) is widely used in Ayurveda in various cardiovascular diseases. Many animal and clinical studies have validated its anti-ischemic, antihypertensive, antihypertrophic and antioxidant effects. Pulmonary hypertension (pH) is a fatal disease which causes right ventricular hypertrophy and right heart failure. Pulmonary vascular smooth muscle hypertrophy and increased oxidative stress are major pathological features of pH...
July 8, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27358792/cavitary-lung-lesion-6-years-after-renal-transplantation
#20
Arun Kumar Subbiah, Sudheer Arava, Soumita Bagchi, Karan Madan, Chandan J Das, Sanjay Kumar Agarwal
The differential diagnoses of a cavitary lung lesion in renal transplant recipients would include infection, malignancy and less commonly inflammatory diseases. Bacterial infection, Tuberculosis, Nocardiosis, fungal infections like Aspergillosis and Cryptococcosis need to be considered in these patients. Pulmonary cryptococcosis usually presents 16-21 mo after transplantation, more frequently in patients who have a high level of cumulative immunosuppression. Here we discuss an interesting patient who never received any induction/anti-rejection therapy but developed both BK virus nephropathy as well as severe pulmonary Cryptococcal infection after remaining stable for 6 years after transplantation...
June 24, 2016: World Journal of Transplantation
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