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Gynecological endocrinology, hormones.

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https://www.readbyqxmd.com/read/27651724/a-novel-approach-using-a-minimal-number-of-injections-during-the-ivf-icsi-cycle-luteal-half-dose-depot-gnrh-agonist-following-corifollitropin-alfa-versus-the-corifollitropin-alfa-with-a-gnrh-antagonist-cycle
#1
Bülent Haydardedeoğlu, Esra Bulgan Kılıçdağ
OBJECTIVE: Corifollitropin alfa is a good choice for assisted reproductive technology (ART) cycles because fewer injections are needed than with other agents. In this retrospective cohort, we analyzed luteal injected half-dose depot gonadotropin hormone-releasing hormone (GnRH) agonist cycles in women who received corifollitropin alfa and those who underwent a conventional corifollitropin alfa cycle with a GnRH antagonist. MATERIAL AND METHODS: In this retrospective cohort, we analyzed luteal injected half-dose depot GnRH agonist cycles in women who received corifollitropin alfa and those who underwent a conventional corifollitropin alfa cycle with a GnRH antagonist at the Division of Reproductive Endocrinology and IVF Unit, Obstetrics and Gynecology Department, Başkent University School of Medicine, Adana, Turkey, from March 2014 to August 2015...
2016: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/27089404/focus-on-bmi-and-subclinical-hypothyroidism-in-adolescent-girls-first-examined-for-amenorrhea-or-oligomenorrhea-the-emerging-role-of-polycystic-ovary-syndrome
#2
Markella Nezi, Panagiotis Christopoulos, George Paltoglou, Alexandros Gryparis, Vassilios Bakoulas, Efthimios Deligeoroglou, George Creatsas, George Mastorakos
BACKGROUND: Primary amenorrhea, oligomenorrhea and secondary amenorrhea are diagnosed commonly during adolescence. Weight aberrations are associated with menstrual disorders. Autoimmune thyroiditis is frequent during adolescence. In this study, the commonest clinical and hormonal characteristics of amenorrhea or oligomenorrhea during adolescence were investigated. METHODS: In this cross-sectional study, one hundred and thirty-eight consecutive young patients presenting with amenorrhea or oligomenorrhea referred to an adolescent endocrinology and gynecology university clinic were studied...
June 1, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/26859129/spontaneous-endogenous-pulsatile-release-of-kisspeptin-is-temporally-coupled-with-luteinizing-hormone-in-healthy-women
#3
Blazej Meczekalski, Krzysztof Katulski, Agnieszka Podfigurna-Stopa, Adam Czyzyk, Alessandro D Genazzani
OBJECTIVE: To evaluate the presence of a spontaneous pulsatile release of kisspeptin and whether it is temporally coupled to LH pulses. DESIGN: Experimental study. SETTING: Academic medical center. PATIENT(S): Thirty young healthy eumenorrheic women aged 20-37 years were included in the study group. All subjects were white women admitted to the Department of Gynecological Endocrinology, Poznan University of Medical Sciences, Poznan, Poland...
May 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/26440361/serum-leptin-concentration-in-women-of-reproductive-age-with-euthyroid-autoimmune-thyroiditis
#4
Artur Drobniak, Krzysztof Kanecki, Monika Grymowicz, Stanislaw Radowicki
INTRODUCTION: Autoimmune thyroid disease (AITD) with elevated anti-thyroid peroxidase antibody (aTPO) levels appears in 12-25% of all women, apart from thyroid dysfunction. High titers of aTPO are more common in women with polycystic ovary syndrome and endometriosis. Elevated aTPO has been associated with infertility and poorer quality of life among euthyroid women, and may be related to other factors. OBJECTIVES: The aim of the study was to measure differences in serum leptin concentration between AITD+ and AITD- patients...
2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/26345686/diminished-ovarian-reserve-is-not-observed-in-infertility-patients-with-high-normal-cgg-repeats-on-the-fragile-x-mental-retardation-1-fmr1-gene
#5
Ann Schufreider, Dana B McQueen, Sang Mee Lee, Rachel Allon, Meike L Uhler, Jocelyn Davie, Eve C Feinberg
STUDY QUESTION: Does an association exist between high normal numbers of CGG trinucleotide repeats on the fragile X mental retardation 1 (FMR1) gene and diminished ovarian reserve (DOR)? SUMMARY ANSWER: This large data set demonstrated that a high normal number of CGG repeats (35-54 repeats) on the FMR1 gene was not significantly correlated with DOR. WHAT IS KNOWN ALREADY: The FMR1 premutation (55-200 repeats) is a known cause of primary ovarian insufficiency...
November 2015: Human Reproduction
https://www.readbyqxmd.com/read/26298398/turner-syndrome-from-birth-to-adulthood
#6
Isabel Ríos Orbañanos, Amaia Vela Desojo, Lorea Martinez-Indart, Gema Grau Bolado, Amaya Rodriguez Estevez, Itxaso Rica Echevarria
BACKGROUND: Turner syndrome is characterized by a great variability of clinical manifestations caused by a total or partial loss of X-chromosome. PATIENTS AND METHODS: A retrospective, descriptive study of the diagnosis, course, and current status of patients with Turner syndrome followed up at our section over the past 40 years, based on review of medical records supplemented with a telephone survey. RESULTS: Forty-five female patients with a current mean age of 22...
December 2015: Endocrinología y Nutrición: órgano de la Sociedad Española de Endocrinología y Nutrición
https://www.readbyqxmd.com/read/26231608/the-role-of-kisspeptin-in-the-onset-of-puberty-and-in-the-ovulatory-mechanism-a-mini-review
#7
REVIEW
Manuel E Cortés, Bárbara Carrera, Hernán Rioseco, Juan Pablo del Río, Pilar Vigil
The onset of puberty has been a fascinating topic for reproductive endocrinologists for decades; however, its underlying physiological mechanisms have remained elusive until recently. The discovery and understanding of the effects exerted by the peptide hormone kisspeptin have shed light on this research area. This review is aimed to discuss the functions of kisspeptin, with special focus on its role in the onset of puberty and in the ovulatory mechanism. The points under discussion are (1) the characteristics of kisspeptin and its receptor, (2) the relevance of this hormone and its interaction with leptin in the onset of puberty, (3) the role of kisspeptin in the ovulatory mechanism based on its differential expression at hypothalamic nuclei, which is modulated by sex steroid hormones, and (4) the clinical relevance of kisspeptin and its antagonists in new therapeutic strategies for the treatment of various reproductive pathologies...
October 2015: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/26165561/hormonal-and-psychosocial-correlates-of-psychological-well-being-and-negative-affectivity-in-young-gynecological-endocrinological-patients
#8
Rafal Watrowski, Anke Rohde, Marzena Maciejewska-Jeske, Blazej Meczekalski
To study the relationship between hormones, psychosocial factors and psychological well-being or negative affectivity (NA), 102 women (aged 15-31) responded to the 12-item well-being questionnaire (W-BQ12), with subscales for positive well-being (PWB), negative well-being (NWB) and energy (ENE); the Hospital Anxiety and Depression Scale (HADS), consisting of depression (HADS-D) and anxiety (HADS-A) subscales; the Beck Depression Inventory (BDI), and the Hamilton Depression Scale (HAMD). The univariate analysis revealed significant negative correlations between luteinizing hormone (LH) and HADS-T, HADS-D and HADS-A, and between follicle stimulating hormone (FSH) and HADS-A...
2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/26151994/depressive-symptoms-and-hormonal-profile-in-climacteric-women
#9
R Słopień, A Słopień, A Warenik-Szymankiewicz, S Sajdak
OBJECTIVES: The aims of the study were: evaluation of depressive symptoms in climacteric women, comparison of depressive symptoms between peri- and post-menopausal women, and assessment of a possible relationship between the presence of depressive symptoms and the hormonal profile of the studied women. MATERIALS AND METHODS: The study included 45 peri-menopausal and 95 post-menopausal women admitted to the Department of Gynecological Endocrinology, Poznafi University of Medical Sciences, because of climacteric symptoms...
2015: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26051098/validity-of-adiponectin-to-leptin-and-adiponectin-to-resistin-ratios-as-predictors-of-polycystic-ovary-syndrome
#10
Sameh Sarray, Samira Madan, Layal R Saleh, Naeema Mahmoud, Wassim Y Almawi
OBJECTIVE: To evaluate the association of changes in adipokine ratios with polycystic ovary syndrome (PCOS) and related features as altered levels of the adipokines adiponectin, leptin, and resistin were linked with the pathogenesis of PCOS. DESIGN: Case-control retrospective study. SETTING: Outpatient obstetrics/gynecology and adult endocrinology clinics. PATIENT(S): Unrelated women with PCOS (n = 211) and age-matched control women (n = 215)...
August 2015: Fertility and Sterility
https://www.readbyqxmd.com/read/25932401/prevalence-of-thyroid-dysfunction-among-women-during-the-first-trimester-of-pregnancy-at-a-tertiary-care-hospital-in-haryana
#11
Rajesh Rajput, Vasudha Goel, Smiti Nanda, Meena Rajput, Shashi Seth
BACKGROUND: Undetected and untreated thyroid disorders are associated with adverse maternal and fetal outcomes. There are limited data on the prevalence of newly diagnosed thyroid disease during pregnancy from India. Therefore, this study was designed to evaluate the prevalence of thyroid dysfunction, especially hypothyroidism during the first trimester of pregnancy. MATERIALS AND METHODS: The present cross-sectional study was conducted at Department of endocrinology and antenatal clinic in the Obstetrics and Gynecology Pt...
May 2015: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/25772812/prevalence-of-conditions-causing-chronic-anovulation-and-the-proposed-algorithm-for-anovulation-evaluation
#12
Pitch Chandeying, Tawiwan Pantasri
AIM: This study investigated the prevalence of disease-causing chronic anovulation and proposes a logical investigation flowchart to facilitate diagnosis in women presenting with chronic anovulation. MATERIAL AND METHODS: The cross-sectional retrospective study was performed using 293 reproductive-aged women who were diagnosed with chronic anovulation at the Gynecologic Endocrinology Unit, Faculty of Medicine, Chiang Mai University between January 2008 and December 2012...
July 2015: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/25309816/preliminary-hormonal-correlations-in-female-patients-as-a-function-of-somatic-and-neurological-symptom-clusters-an-exploratory-development-of-a-multi-hormonal-map-for-bio-identical-replacement-therapy-mhrt
#13
Eric R Braverman, Marlene Oscar-Berman, Florian Kreuk, Mallory Kerner, Kristina Dushaj, Mona Li, Danielle Stratton, Courtney Trudesdell, Kenneth Blum
Females develop multiple hormonal alterations and certain genes may be involved in the intensity of subsequent symptoms including both mood and drug seeking. Seventy Four (74) females were included (mean age=60.23, SD=9.21, [43-87]). A medical evaluation was completed with hormone screening using a number of statistical analyses such as Pearson product moment; one way ANOVA and Regression analysis along with a Bonferroni significance correction p<.004. Of 120 correlations performed, significant hormone/domain correlations were as follows: DHEA/Genitourinary (r=...
December 6, 2013: Journal of Genetic Syndrome & Gene Therapy
https://www.readbyqxmd.com/read/25242338/selective-progesterone-receptor-modulators-a-class-with-multiple-actions-and-applications-in-reproductive-endocrinology-and-gynecology
#14
REVIEW
Philippe Bouchard
Among the remarkable progress made in the treatment of hormone-dependent diseases, recently selective steroid receptor modulators (SPRM) have been remarkable tools to improve the prognosis of multiple hormone-dependent cancers (breast, prostate). Because of their remarkable properties, both agonistic and mainly antagonistic, to modulate progesterone action. They have allowed a better understanding of progesterone action and progress in contraception and treatment of abnormal uterine bleeding as well as in the medical treatment of uterine fibroids...
October 2014: Gynecological Endocrinology
https://www.readbyqxmd.com/read/24782012/luteal-phase-support-in-art-treatments
#15
Yuval Or, Edi Vaisbuch, Zeev Shoham
In a normal spontaneous menstrual cycle, the luteal phase is characterized by the production and secretion of estradiol (E) and progesterone (P) from the corpus luteum (CL) in an episodic manner. The steroidogenesis of the CL is dependent on continued tonic luteinizing hormone (LH) secretion (Fritz and Speroff, Clinical gynecologic endocrinology and infertility, 8th edn. Wolters Kluwer, Lippincott Williams & Wilkins, Philadelphia, 2011). The dependence of the CL was further supported by the prompt luteolysis that followed the administration of GnRH analogues or withdrawal of GnRH when ovulation has been induced by the administration of pulsatile GnRH (Hutchison and Zeleznik, Endocrinology 115:1780-1786, 1984; Fraser et al...
2014: Methods in Molecular Biology
https://www.readbyqxmd.com/read/24736196/knowledge-and-personal-use-of-menopausal-hormone-therapy-among-chinese-obstetrician-gynecologists-results-of-a-survey
#16
Yanjie Wang, Xin Yang, Xiaodong Li, Xiaojing He, Yang Zhao
OBJECTIVE: Obstetrician-gynecologists' (ob-gyns) knowledge of the benefits and risks of-and attitude toward-menopausal hormone therapy (HT) have evolved since the publication of the Heart and Estrogen/progestin Replacement Study and the Women's Health Initiative. The survey investigated Chinese ob-gyns' perception and personal use of-and attitude toward-HT. METHODS: A total of 2,000 self-administered questionnaires were sent to female ob-gyns who attended gynecological endocrinology workshops in 15 provinces and cities in China from February to May 2013...
November 2014: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/24715185/testicular-feminization-complete-androgen-insensitivity-syndrome-discussions-based-on-a-case-report
#17
Constantin Gîngu, Alexandru Dick, Sorin Pătrăşcoiu, Liliana Domnişor, Mihaela Mihai, Mihai Hârza, Ioanel Sinescu
INTRODUCTION AND OBJECTIVES: Testicular feminization is the syndrome when a male, genetically XY, because of various abnormalities of the X chromosome, is resistant to the actions of the androgen hormones, which in turn stops the forming of the male genitalia and gives a female phenotype. The androgen insensitivity syndrome occurs in one out of 20,000 births and can be incomplete (various sexual ambiguities) or complete (the person appears to be a woman). The aim of this paper is to present the diagnosis and treatment of a case of testicular feminization...
2014: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/24639712/anti-mullerian-and-androgens-hormones-in-women-with-polycystic-ovary-syndrome-undergoing-ivf-icsi
#18
Menha Swellam, Abeer Khaial, Tamer Mosa, Hatim El-Baz, Mohamed Said
BACKGROUND: Despite its frequency, the polycystic ovary syndrome (PCOS) is still a difficult diagnosis in endocrinology, gynecology, and reproductive medicine. The Rotterdam consensus conference proposed to include the ultrasonographic follicle count as a new diagnostic criterion. Unfortunately, its assessment does not offer sufficient reliability worldwide. OBJECTIVE: To explore the possible roles of altered circulating androgens and anti-mullerian hormone among PCOS women regarding their body mass index and their outcomes after IVF...
November 2013: Iranian Journal of Reproductive Medicine
https://www.readbyqxmd.com/read/24628922/cutaneous-manifestations-of-the-subtypes-of-polycystic-ovary-syndrome-in-korean-patients
#19
J S Hong, H H Kwon, S Y Park, J Y Jung, J Y Yoon, S Min, Y M Choi, D H Suh
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in women of childbearing-age. Although PCOS has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of PCOS patients in Asia. OBJECTIVE: The goal of this study is to elucidate the dermatological characteristics and metabolic and hormonal parameters of Korean PCOS patients classified by the three ASRM/ESHERE criteria...
January 2015: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/24483042/-reasons-for-abandonment-of-hormone-replacement-therapy-with-tibolone-in-menopausal-women
#20
Francisco Javier Zayas-Jaime, José Manuel Ornelas-Aguirre, Dalia Elizabeth Pérez-Nápoles
BACKGROUND: Hormone replacement therapy (HRT) with tibolone used in the management of menopause has low rates of acceptance and compliance in the first year. Few studies analyze the reasons for abandoning the use of tibolone. OBJECTIVE: To analyze the reasons for abandoned tibolone hormone replacement therapy in postmenopausal women and the effects of the drug through the years in the treatment. MATERIAL AND METHODS: In a cross-sectional study, were included 261 menopausal women between 40 and 60 year old who attended their disease control at the Gynaecological Endocrinology serving in the National Medical Center Northwest in Obregon City, Sonora, Mexico during 2010-2011...
October 2013: Ginecología y Obstetricia de México
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