Read by QxMD icon Read

wertheim hysterectomy

Alexa L Swailes, Allison Gockley, Rébécca Phaëton, Joshua P Kesterson
Ernst Wertheim was a pioneer in the history of the surgical treatment of cervical cancer. His English-language manuscript "The extended abdominal operation for carcinoma uteri (based on 500 operative cases)," which was published in 1912, detailed his standardization of the radical hysterectomy and formed the basis of the current treatment for early stage cervical cancer. We contextualize the Wertheim hysterectomy, emphasizing medical advances that allowed for its development and subsequent modification. We then discuss modifications to the originally proposed procedure, including a maximally extended parametrical resection pioneered by Takayama, and the addition of the Taussig en bloc lymph node dissection by Meigs, both of which afforded an improved mortality profile due to decreased disease recurrence...
April 2017: Gynecologic Oncology
Carolina de Mendonça Coutinho E Silva, Octavio Muniz da Costa Vargens
OBJECTIVES: to describe the feelings and perceptions resulting from gynecologic surgery by women and analyze how they experience the changes caused by the surgery. METHOD: a qualitative, descriptive and exploratory study, which had Symbolic Interactionism and Grounded Theory as its theoretical framework. Participants of the study: 13 women submitted to surgery: Total Abdominal Hysterectomy, Total Abdominal Hysterectomy with bilateral Adnexectomy, Wertheim-Meigs surgery, Oophorectomy, Salpingectomy, Mastectomy, Quadrantectomy and Tracheloplasty...
August 29, 2016: Revista Latino-americana de Enfermagem
Marloes Derks, Jacobus van der Velden, Minke M Frijstein, Willemijn M Vermeer, Anne M Stiggelbout, Jan Paul W R Roovers, Cornelis D de Kroon, Moniek M Ter Kuile, Gemma G Kenter
OBJECTIVE: This study aimed to compare urinary and bowel symptoms and quality of life (QoL) among women treated with a Wertheim-Meigs (WM, type III) or Wertheim-Okabayashi (WO, type IV) radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer. METHODS: In this cross-sectional observational study, patients treated with a WO or a (nerve sparing) WM radical hysterectomy (with or without adjuvant radiotherapy) between January 2000 and December 2010 in the Center for Gynaecological Oncology Amsterdam or Leiden University Medical Center were included...
October 2016: International Journal of Gynecological Cancer
A Dierickx, M Göker, G Braems, P Tummers, R Van den Broecke
A mesonephric adenocarcinoma of the cervix is a very rare tumor deriving from remnants of the mesonephric duct. Differential diagnosis from other cervical carcinomas is difficult and little is known regarding its biological behavior, prognosis, and the optimal management strategy. We present a case of a mesonephric adenocarcinoma of the cervix with a comprehensive review of the existing literature. In this case a 66-year-old woman presented with postmenopausal vaginal bleeding. She was diagnosed with a FIGO stage IIB mesonephric adenocarcinoma of the cervix and treated with neoadjuvant chemoradiotherapy and a Wertheim hysterectomy...
August 2016: Gynecologic Oncology Reports
Cecilia Kärrberg, Thomas Rådberg, Erik Holmberg, Anders Norström
OBJECTIVE: To evaluate all cases of cervical cancer associated with pregnancy during 16 years in the Western Region of Sweden. DESIGN: Retrospective, descriptive cohort study. SETTING AND POPULATION: All women with cervical cancer, diagnosed during pregnancy or within 6 months after parturition, between 1993 and 2008. METHODS: The study was based on data from different registers and medical records. MAIN OUTCOME MEASURES: Incidence, diagnostic measures, treatment and outcome of disease...
June 2015: Acta Obstetricia et Gynecologica Scandinavica
F Marin, M Plesca, C I Bordea, M A Moga, A Blidaru
The treatment for cervical cancer is a complex, multidisciplinary issue, which applies according to the stage of the disease. The surgical elective treatment of cervical cancer is represented by the radical abdominal hysterectomy. In time, many surgeons perfected this surgical technique; the ones who stood up for this idea were Thoma Ionescu and Ernst Wertheim. There are many varieties of radical hysterectomies performed by using the abdominal method and some of them through vaginal and mixed way. Each method employed has advantages and disadvantages...
June 15, 2014: Journal of Medicine and Life
E Sowa, S Kuhnt, A Hinz, C Schröder, T Deutsch, K Geue
Introduction: The present study compares for the first time the standard therapy for cervical cancer in FIGO-stages IB-IIB, radical hysterectomy according to the Wertheim-Meigs operation, with the newly developed, nerve-sparing surgical technique, total mesometrial resection (TMMR) with regard to postoperative, health-related quality of life. Method: In the framework of a multicentre, retrospective cohort study a total of 110 cervical cancer patients were interviewed once by means of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the cervical cancer module (EORTC QLQ-CX24)...
July 2014: Geburtshilfe und Frauenheilkunde
Julia Vízkeleti, Ildikó Vereczkey, Georgina Fröhlich, Szilvia Varga, Katalin Horváth, Tamás Pulay, Imre Pete, Csaba Nemeskéri, Árpád Mayer, Norbert Sipos, Miklós Kásler, Csaba Polgár
The role of preoperative intrauterine brachytherapy (BT) in the multidisciplinary treatment of early stage cervical carcinoma (ESCC) is controversial. In 2005, a prospective randomized multicenter study was initiated in Hungary in order to explore the potential advantages of preoperative high-dose-rate (HDR) BT. In this article we evaluate the efficiency of preoperative HDR BT by the rate of pathologic complete remission (pCR) in the first 185 patients enrolled in the study at the National Institute of Oncology and at the Uzsoki Municipal Cancer Center in collaboration with the 1st Department of Gynaecology and Obstetrics of Semmelweis University, Budapest, Hungary...
April 2015: Pathology Oncology Research: POR
M Mangler, N Zech, A Schneider, C Köhler, S Marnitz
Introduction: In spite of the existence of guidelines and international recommendations, many aspects in the diagnosis, therapy and follow-up of patients with cervical cancer are not based on validated data. A broad spectrum of different opinions and procedures concerning the therapy for patients with cervical cancer is under controversial discussion by the responsible gynaecologists in German hospitals. Methods: The present study is intended to picture the current treatment situation for cervical cancer in Germany...
March 2013: Geburtshilfe und Frauenheilkunde
Satwant Kumar, Madhu Lata Rana, Khushboo Verma, Narayanjeet Singh, Anil Kumar Sharma, Arun Kumar Maria, Gobind Singh Dhaliwal, Harkiran Kaur Khaira, Sunil Saini
BACKGROUND: Cervical cancer is the third largest cause of cancer mortality in India. The objectives of the study were to compare the pre and the post treatment quality of life in cervical cancer patients and to develop a prediction model to provide an insight into the possibilities in the treatment modules. METHODOLOGY/PRINCIPAL FINDINGS: A total of 198 patients were assessed with two structured questionnaires of Health Related Quality of Life (The European Organisation for Research and Treatment of Cancer, EORTC QLQ C-30 and CX-24)...
2014: PloS One
Yong Kuei Lim, Yin Nin Chia, Kwai Lam Yam
INTRODUCTION: For many decades, Wertheim's radical hysterectomy via laparotomy, also known as Wertheim's radical abdominal hysterectomy (RAH), has been the traditional surgical approach for operable stage IB cervical cancer. However, many established cancer centres worldwide have recently shown total laparoscopic Wertheim's radical hysterectomy (TLRH) to be a safe and feasible alternative to the conventional abdominal route for early cervical cancer management. This technique was introduced in Singapore in 2009...
December 2013: Singapore Medical Journal
Hema Sinhasane, Sarvottam B Rao
No abstract text is available yet for this article.
December 2012: Journal of Obstetrics and Gynaecology of India
A C Kraima, M Derks, N N Smit, J C Van Munsteren, J Van der Velden, G G Kenter, M C DeRuiter
OBJECTIVE: Radical hysterectomy with pelvic lymphadenectomy is the treatment of choice for early-stage cervical cancer. Wertheim's original technique has been often modified, mainly in the extent of parametrectomy. Okabayashi's technique is considered as the most radical variant regarding removal of the ventral parametrium and paracolpal tissues. Surgical outcome concerning recurrence and survival is good, but morbidity is high due to autonomic nerve damage. While the autonomic network has been studied extensively, the lymphatic system is less understood...
January 2014: Gynecologic Oncology
Zdenko Kraljević, Klaudija Visković, Mario Ledinsky, Dijana Zadravec, Ivan Grbavac, Marijana Bilandzija, Hrvojka Soljacić-Vranes, Krunoslav Kuna, Ksenija Klasnić, Ivan Krolo
The most commonly used staging system for cervical cancer is based on the International Federation of Gynaecology and Obstetrics (FIGO) staging system. Magnetic resonance imaging (MRI) has been accepted as the optimal tool for evaluation of the main prognostic factors and selection of therapeutic strategy. The purpose of this study was to compare the preoperative clinical examination FIGO staging findings with MRI and postoperative pathology report in females with primary cancer of the cervix. The study prospectively included 46 females consecutively hospitalized at the Department of Gynaecology and Obstetrics at the "Sestre milosrdnice" University Hospital Center in Zagreb...
June 2013: Collegium Antropologicum
Subhankar Dasgupta, Ranen Kanti Aich, Asit Ranjan Deb, Phalguni Gupta
Adenoma malignum is a rare variant of cervical adenocarcinoma which presents a great diagnostic and therapeutic challenge to an oncologist. A 31-year-old woman presented with a mass filling up whole of the vagina which showed no evidence of malignancy by scraping cytology or punch biopsy. But histological examination of the resected mass turned up to be adenoma malignum of the cervix. The patient was subsequently treated by Wertheim's hysterectomy and radiotherapy.
December 2012: Journal of the Indian Medical Association
Nilanchali Singh, Reva Tripathi, Yedla Manikya Mala
We report a case of primary malignant melanoma of cervix which is a rare malignancy with only around 60 cases being reported. This patient presented with bleeding per vaginum. A large exophytic growth from cervix with black discolouration was seen. International Federation of Gynaecology and Obsterics (FIGO) staging was stage IIa. Histoimmunocytology confirmed the diagnosis of malignant melanoma of cervix. S-100 and HMB-45 are reliable markers for cervical melanomas. We attempted Wertheim's hysterectomy; but, due to extensive disease, paravescical and pararectal fossae could not be dissected and we had to perform type I hysterectomy...
2013: BMJ Case Reports
Supriya Chopra, Reena Engineer, Umesh Mahantshetty, Shagun Misra, Reena Phurailatpam, Siji N Paul, Sadhna Kannan, Rajendra Kerkar, Amita Maheshwari, Ts Shylasree, Jaya Ghosh, Sudeep Gupta, Biji Thomas, Shalini Singh, Sanjiv Sharma, Srinivas Chilikuri, Shyam Kishore Shrivastava
INTRODUCTION: External beam radiation followed by vaginal brachytherapy (±chemotherapy) leads to reduction in the risk of local recurrence and improves progression-free survival in patients with adverse risk factors following Wertheim's hysterectomy albeit at the risk of late bowel toxicity. Intensity Modulated Radiotherapy (IMRT) results in reduction in bowel doses and has potential to reduce late morbidity, however, needs to be confirmed prospectively in a randomised trial. The present randomised trial tests reduction if any in late small bowel toxicity with the use of IMRT in postoperative setting...
2012: BMJ Open
Júlia Vízkeleti, Imre Pete, Ildikó Vereczkey, Georgina Fröhlich, Katalin Horváth, Szilvia Varga, Tamás Pulay, Miklós Kásler, Csaba Polgár
The purpose of the study was a preliminary evaluation of the efficacy of preoperative intracavitary high-dose-rate brachytherapy (HDR BT) in sterilization of the specimen of operable cervical cancer patients enrolled into a prospective, randomized study. Between 2005 and 2010, 100 operable cervical cancer patients of FIGO stage I/A2 (n=4), I/B1 (n=51), I/B2 (n=19), IIA (n=17), and proximal II/B (n=9) were randomized in two arms: in arm "A" (n=50) allocated treatment was 2x8 Gy preoperative intracavitary HDR BT followed by radical surgery, in arm "B" (n= 50) no preoperative treatment was given before the planned radical Wertheim hysterectomy...
September 2012: Magyar Onkologia
Daniela Freitas, Fedra Rodrigues, Daniel Fernandes, Almerinda Petiz
OBJECTIVES: Review and critical analysis of the Wertheim-Meigs Operations performed at our institution in the context of cervical cancer and to assess the proportion who underwent treatment with adjuvant radiotherapy (with or without chemotherapy) and the main indications. MATERIAL AND METHODS: Retrospective review of Wertheim-Meigs operations, conducted in the context of carcinoma of the cervix, between 01.01.2005 and 31.12.2010, through consultation with clinical processes...
December 2011: Acta Médica Portuguesa
Bharat Rekhi, Bharti Patil, Kedar K Deodhar, Amita Maheshwari, Rajendra A Kerkar, Sudeep Gupta, Hemant B Tongaonkar, Shyam Kishore Shrivastava
Neuroendocrine carcinomas of the cervix are uncommon, characterized by a histomorphological spectrum and, mostly, an aggressive clinical course. There are only few substantial studies on such cases documented from our country, where cervical cancer is the second most common cancer affecting women. Herein, we present a spectrum of 50 cervical neuroendocrine carcinomas, including histopathologic features, terminology, immunohistochemical (IHC) profile, and clinical outcomes, wherever available. Fifty tumors occurred in women, with their age ranging from 23 to 69 years (mean, 48...
February 2013: Annals of Diagnostic Pathology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"