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https://www.readbyqxmd.com/read/28441712/virus-based-devices-prospects-for-allopoiesis
#1
Bogdan Dragnea
The assembly line is a commonly invoked example of allopoiesis, the process whereby a system produces a different system than itself. In this sense, virus production in plants is an instance of bio-enabled bottom-up allopoiesis because the plant host can be regarded as a programmable assembly line for the virus. Reprogramming this assembly line and integrating it into a larger lineup of chemical manipulations has seen a flurry of activity recently, with more sophisticated systems emerging every year. The field of virus nanomaterials now has several subdisciplines that focus on virus shells as assemblers, scaffolds for molecular circuitry, chemical reactors, magnetic and photonic beacons, and therapeutic carriers...
April 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28438107/accessing-care-summaries-at-point-of-care-implementation-of-mobile-devices-for-personal-carers-in-aged-care
#2
Rachel E Brimelow, Annie Gibney, Suzanne Meakin, Judy A Wollin
Continued development of mobile technology now allows access to information at the point-of-care. This study was conducted to evaluate the use of one such tool on a mobile device, from the carer perspective. Caregivers across 12 aged-care facilities were supplied mobile devices to access a Picture Care Plan (PCP), a specific tool designed around the role of the personal carer. An anonymous questionnaire was subsequently completed by 85 carers with questions relating to participants' experience. Perceived helpfulness of the PCP at the point-of-care was high (87%)...
April 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28433015/probing-the-effects-of-surface-hydrophobicity-and-tether-orientation-on-antibody-antigen-binding
#3
Derek B Bush, Thomas A Knotts
Antibody microarrays have the potential to revolutionize molecular detection for many applications, but their current use is limited by poor reliability, and efforts to change this have not yielded fruitful results. One difficulty which limits the rational engineering of next-generation devices is that little is known, at the molecular level, about the antibody-antigen binding process near solid surfaces. Atomic-level structural information is scant because typical experimental techniques (X-ray crystallography and NMR) cannot be used to image proteins bound to surfaces...
April 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28398369/-percutaneous-treatment-of-complex-post-myocardial-infarction-ventricular-septal-defect-case-report-and-literature-review
#4
Elisabetta Moscarella, Giuseppe Santoro, Gianpiero Gaio, Teresa Palladino, Angelo Fabio D'Aiello, Heba Talat Mahmoud, Maurizio Cappelli Bigazzi, Maria Giovanna Russo
Post-myocardial infarction (MI) ventricular septal defects (VSD) are a rare but life-threatening complication of acute MI, with very high mortality rates even if timely approached by surgical repair. Transcatheter closure is an attractive alternative to surgery. However, this option is currently deemed challenging and often unsuitable in complex VSD. We report the case of a young woman in poor hemodynamic conditions due to a complex post-MI VSD. A two-step percutaneous VSD closure was successfully performed adopting a patient-tailored approach based on a throughout knowledge of the anatomic and functional picture using both commercially available dedicated and off-label devices...
February 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28397485/large-area-cross-aligned-silver-nanowire-electrodes-for-flexible-transparent-and-force-sensitive-mechanochromic-touch-screens
#5
Seungse Cho, Saewon Kang, Ashish Pandya, Ravi Shanker, Ziyauddin Khan, Youngsu Lee, Jonghwa Park, Stephen L Craig, Hyunhyub Ko
Silver nanowire (AgNW) networks are considered to be promising structures for use as flexible transparent electrodes for various optoelectronic devices. One important application of AgNW transparent electrodes is the flexible touch screens. However, the performances of flexible touch screens are still limited by the large surface roughness and low electrical to optical conductivity ratio of random network AgNW electrodes. In addition, although the perception of writing force on the touch screen enables a variety of different functions, the current technology still relies on the complicated capacitive force touch sensors...
April 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28377253/implementing-functional-preoperative-mapping-in-the-clinical-routine-of-a-neurosurgical-department-technical-note
#6
Nico Sollmann, Bernhard Meyer, Sandro M Krieg
BACKGROUND: Navigated transcranial magnetic stimulation (nTMS) is increasingly being used for mapping of various brain functions and nTMS-based tractography in neurosurgical departments worldwide. When a department starts integrating nTMS data into the clinical workflow, smooth implementation in the existing hospital's infrastructure is mandatory. However, standardized approaches beyond the mapping or tractography procedures themselves have not yet been described. METHODS: To create an effective workflow for neurosurgical nTMS mapping, we present the results of our 7 years of experience and progressive integration into clinical routine...
April 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28373984/evaluation-of-a-compact-hybrid-brain-computer-interface-system
#7
Jaeyoung Shin, Klaus-Robert Müller, Christoph H Schmitz, Do-Won Kim, Han-Jeong Hwang
We realized a compact hybrid brain-computer interface (BCI) system by integrating a portable near-infrared spectroscopy (NIRS) device with an economical electroencephalography (EEG) system. The NIRS array was located on the subjects' forehead, covering the prefrontal area. The EEG electrodes were distributed over the frontal, motor/temporal, and parietal areas. The experimental paradigm involved a Stroop word-picture matching test in combination with mental arithmetic (MA) and baseline (BL) tasks, in which the subjects were asked to perform either MA or BL in response to congruent or incongruent conditions, respectively...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28365240/using-electronic-health-records-to-build-an-ophthalmological-data-warehouse-and-visualize-patients-data
#8
Karsten U Kortüm, Michael Müller, Christoph Kern, Alexander Babenko, Wolfgang J Mayer, Anselm Kampik, Thomas C Kreutzer, Siegfried Priglinger, Christoph Hirneiss
PURPOSE: To develop a near real-time data warehouse (DW) in an academic ophthalmological center to gain scientific use of increasing digital data from electronic medical records (EMR) and diagnostic devices. Design; Database development METHODS: Specific macular clinic user interfaces within the institutional hospital information system were created. Orders for imaging modalities were sent by an EMR -linked picture-archiving and communications system to the respective devices. All data of 325,767 patients since 2002 were gathered in a DW running on a SQL database...
March 29, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28362668/new-role-of-ventricular-assist-devices-as-bridge-to-transplantation-european-perspective
#9
David C Reineke, Paul J Mohacsi
PURPOSE OF REVIEW: Progress of ventricular assist devices (VAD) technology led to improved survival and apparently low morbidity. However, from the European perspective, updated analysis of EUROMACS reveals a somewhat less impressive picture with respect to mortality and morbidity. RECENT FINDINGS: We describe the great demand of cardiac allografts versus the lack of donors, which is larger in Europe than in the United States. Technical progress of VADs made it possible to work out a modern algorithm of bridge-to-transplant, which is tailored to the need of the particular patient...
March 30, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28335445/deciphering-egyptian-hieroglyphs-towards-a-new-strategy-for-navigation-in-museums
#10
Jaime Duque-Domingo, Pedro Javier Herrera, Enrique Valero, Carlos Cerrada
This work presents a novel strategy to decipher fragments of Egyptian cartouches identifying the hieroglyphs of which they are composed. A cartouche is a drawing, usually inside an oval, that encloses a group of hieroglyphs representing the name of a monarch. Aiming to identify these drawings, the proposed method is based on several techniques frequently used in computer vision and consists of three main stages: first, a picture of the cartouche is taken as input and its contour is localized. In the second stage, each hieroglyph is individually extracted and identified...
March 14, 2017: Sensors
https://www.readbyqxmd.com/read/28333448/role-of-oxygen-functionalities-in-graphene-oxide-architectural-laminate-subnanometer-spacing-and-water-transport
#11
Carlo Alberto Amadei, Andrea Montessori, Julian P Kadow, Sauro Succi, Chad D Vecitis
Active research in nanotechnology contemplates the use of nanomaterials for environmental engineering applications. However, a primary challenge is understanding the effects of nanomaterial properties on industrial device performance and translating unique nanoscale properties to the macroscale. One emerging example consists of graphene oxide (GO) membranes for separation processes. Thus, here we investigate how individual GO properties can impact GO membrane characteristics and water permeability. GO chemistry and morphology were controlled with easy-to-implement photoreduction and sonication techniques and were quantitatively correlated, offering a valuable tool for accelerating characterization...
April 6, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28323639/the-effect-of-boundary-slippage-and-nonlinear-rheological-response-on-flow-of-nanoconfined-water
#12
Amandeep Sekhon, V J Ajith, Shivprasad Patil
The flow of water confined to nanometer-sized pores is central to a wide range of subjects from biology to nanofluidic devices. Despite its importance, a clear picture about nanoscale fluid dynamics is yet to emerge. Here we measured dissipation in less than 25 nm thick water films and it was found to decrease for both wetting and non-wetting confining surfaces. The fitting of Carreau-Yasuda model of shear thinning to our measurements implies that flow is non-Newtonian and for wetting surfaces the no-slip boundary condition is largely valid...
May 24, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28320688/implementation-of-a-home-monitoring-system-for-heart-failure-patients-a-feasibility-study
#13
Martin Steven Kohn, Jeffrey Haggard, Jack Kreindler, Kade Birkeland, Ilan Kedan, Raymond Zimmer, Raj Khandwalla
BACKGROUND: Improving the management of patients with complex chronic disease is a substantial undertaking with the simultaneous goals of improving patient outcomes and controlling costs. Reducing avoidable hospitalization for such patients is a step toward both objectives. Some of the deterioration experienced in chronic disease patients occurs outside the view of their clinicians, and before the patient becomes overtly symptomatic. Home monitoring has been used for more than 20 years to detect deterioration earlier so that the patients could be treated before they became ill enough to require hospitalization...
March 20, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28300955/prototype-app-for-voice-therapy-a-peer-review
#14
Paula Lavaissiéri, Paulo Eduardo Damasceno Melo
Purpose: Voice speech therapy promotes changes in patients' voice-related habits and rehabilitation. Speech-language therapists use a host of materials ranging from pictures to electronic resources and computer tools as aids in this process. Mobile technology is attractive, interactive and a nearly constant feature in the daily routine of a large part of the population and has a growing application in healthcare. To develop a prototype application for voice therapy, submit it to peer assessment, and to improve the initial prototype based on these assessments...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28268697/analysis-of-comfort-and-ergonomics-for-clinical-work-environments
#15
Ali Shafti, Beatriz Urbistondo Lazpita, Oussama Elhage, Helge A Wurdemann, Kaspar Althoefer
Work related musculoskeletal disorders (WMSD) are a serious risk to workers' health in any work environment, and especially in clinical work places. These disorders are typically the result of prolonged exposure to non-ergonomic postures and the resulting discomfort in the workplace. Thus a continuous assessment of comfort and ergonomics is necessary. There are different techniques available to make such assessments, such as self-reports on perceived discomfort and observational scoring models based on the posture's relevant joint angles...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226884/analysis-of-comfort-and-ergonomics-for-clinical-work-environments
#16
Ali Shafti, Beatriz Urbistondo Lazpita, Oussama Elhage, Helge A Wurdemann, Kaspar Althoefer, Ali Shafti, Beatriz Urbistondo Lazpita, Oussama Elhage, Helge A Wurdemann, Kaspar Althoefer, Helge A Wurdemann, Beatriz Urbistondo Lazpita, Kaspar Althoefer, Ali Shafti, Oussama Elhage
Work related musculoskeletal disorders (WMSD) are a serious risk to workers' health in any work environment, and especially in clinical work places. These disorders are typically the result of prolonged exposure to non-ergonomic postures and the resulting discomfort in the workplace. Thus a continuous assessment of comfort and ergonomics is necessary. There are different techniques available to make such assessments, such as self-reports on perceived discomfort and observational scoring models based on the posture's relevant joint angles...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28221755/multilevel-ultrafast-flexible-nanoscale-nonvolatile-hybrid-graphene-oxide-titanium-oxide-memories
#17
V Karthik Nagareddy, Matthew D Barnes, Federico Zipoli, Khue T Lai, Arseny M Alexeev, Monica Felicia Craciun, C David Wright
Graphene oxide (GO) resistive memories offer the promise of low-cost environmentally sustainable fabrication, high mechanical flexibility and high optical transparency, making them ideally suited to future flexible and transparent electronics applications. However, the dimensional and temporal scalability of GO memories, i.e., how small they can be made and how fast they can be switched, is an area that has received scant attention. Moreover, a plethora of GO resistive switching characteristics and mechanisms has been reported in the literature, sometimes leading to a confusing and conflicting picture...
March 28, 2017: ACS Nano
https://www.readbyqxmd.com/read/28218360/evaluating-safety-efficacy-and-cost-effectiveness-of-picc-securement-by-subcutaneously-anchored-stabilization-device
#18
Pietro Antonio Zerla, Antonio Canelli, Lidia Cerne, Giuseppe Caravella, Alessandra Gilardini, Giuseppe De Luca, Ana Maria Aricisteanu, Raffaele Venezia
PURPOSE: In recent years, a large variety of medical devices has become available. Every device must be efficient, safe and cost effective, but it is not enough to use it properly without considering the environment in which it will be employed. We applied this kind of analysis to subcutaneously anchored sutureless devices (SAS). METHODS: This is a one-center prospective observational study on safety, effectiveness and cost effectiveness of an SAS device (SecurAcath, Interrad) for securement of peripherally inserted central catheter (PICC) in 30 adult cancer patients with treatment expected to be >60 days...
February 15, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28216791/molecular-processes-leading-to-necking-in-extensional-flow-of-polymer-solutions-using-microfluidics-and-single-dna-imaging
#19
Shaurya Sachdev, Aswin Muralidharan, Pouyan E Boukany
We study the necking and pinch-off dynamics of liquid droplets that contain a semidilute polymer solution of polyacrylamide close to overlap concentration by combining microfluidics and single DNA observation. Polymeric droplets are stretched by passing them through the stagnation point of a T-shaped microfluidic junction. In contrast with the sudden breakup of Newtonian droplets, a stable neck is formed between the separating ends of the droplet which delays the breakup process. Initially, polymeric filaments experience exponential thinning by forming a stable neck with extensional flow within the filament...
December 27, 2016: Macromolecules
https://www.readbyqxmd.com/read/28216666/strong-electronic-interaction-and-multiple-quantum-hall-ferromagnetic-phases-in-trilayer-graphene
#20
Biswajit Datta, Santanu Dey, Abhisek Samanta, Hitesh Agarwal, Abhinandan Borah, Kenji Watanabe, Takashi Taniguchi, Rajdeep Sensarma, Mandar M Deshmukh
Quantum Hall effect provides a simple way to study the competition between single particle physics and electronic interaction. However, electronic interaction becomes important only in very clean graphene samples and so far the trilayer graphene experiments are understood within non-interacting electron picture. Here, we report evidence of strong electronic interactions and quantum Hall ferromagnetism seen in Bernal-stacked trilayer graphene. Due to high mobility ∼500,000 cm(2 )V(-1 )s(-1) in our device compared to previous studies, we find all symmetry broken states and that Landau-level gaps are enhanced by interactions; an aspect explained by our self-consistent Hartree-Fock calculations...
February 20, 2017: Nature Communications
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