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Jean-Pascal Devailly, Laurence Josse
OBJECTIVE: Care programs in MPR formalize, for homogeneous profile of patients the steps of a multidisciplinary approach based on the rehabilitation potential and focused on improving functional status. The aim is to build a custom clinical pathway for patients with stroke followed in Physical Medicine and Rehabilitation Day Hospital by connecting each step systematically formalized a traceability tool in the information system in view a fair payment of a care program. MATERIAL/PATIENTS AND METHODS: Our outpatient hospital PMR team has built a clinical pathway according the method of the High Authority of Health, supported by MPR criteria defined by FEDMER and texts regulating the activity of French post-acute care (SSR)...
September 2016: Annals of Physical and Rehabilitation Medicine
Ambrin Gull Shamas, Karishma Bohara
This work was a retrospective audit of CCAM - 1994 to 2008. A total of 26 cases were identified. Mean gestational age at diagnosis was 20 weeks. All were unilateral and had serial scans. In 31% the lesion resolved, 8% decreased, 42% were unchanged and 4% increased in size. Only one foetus developed hydrops. All were born alive. Of 8 foetuses where the CCAM was thought to have resolved, 6 had persistent lesions (overall sensitivity and PPV of US 64% and 69%, respectively). Computerised tomography performed better than chest X-ray in detecting lesions postnatally (sensitivity 100% vs 88%, PPV 95% vs 78%)...
September 25, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Gang Yu, Bo Xia, Zhu Wang, Baisha Huang, Ying Zhang, Chun Hong, Ning Shang, Jing Tang
OBJECTIVE: To summarize our diagnosis and management experience of congenital bronchial atresia (CBA). METHODS: A retrospective review was conducted, clinical data were collected of all patients with CBA. RESULTS: Among the nine patients (5 males and 4 females), six cases with right side and three cases with left cases, including one patient with mainstem bronchial atresia (MBA), two cases with lobar bronchial atresia (LBA), six cases with segmental bronchial atresia (SBA)...
October 3, 2016: Journal of Maternal-fetal & Neonatal Medicine
A Lipsker, R Saljoghi, D Lecuelle, K Caillet, E Alezra, F Le Roux, M Demailly, F Saint
OBJECTIVES: Patients who are not responding to injectable and/or vacuum oral pharmacological treatments can receive a penile prosthesis. Three types of penile prostheses are used in France: rigid, semi-rigid and inflatable prostheses 3-piece or 2-piece. We have assessed the National surgical insertion practices between 2006 and 2013 (number of prostheses insertions, types, procedure locations, number of surgeons and distribution [public or private sectors]). MATERIALS AND METHODS: Data analysis from the French Technical Agency of Information on Hospitals (ATIH) (2006-2013) using the common classification of medical acts (CCAM) and after code extractions related to this surgery (JHLA002, JHLA003, JHLA004)...
September 2016: Progrès en Urologie
P Chaveeva, V Stratieva, H Shivachev, S Aktash, M Panova, A Shterev
ABSTRACT OBJECTIVE: To present a case of macrocystic type cystic adenomatoid malformation of the lung (CCAM) treated with thoraco-amniotic shunt and to review the published data to evaluate the efficiency of thoraco-amniotic shunts for drainage of (CCAM). MATERIALS AND METHODS: This wass case reported of a fetus with a large thoracic cyst, major mediastinal shift and polyhidramnion treated with thoraco-amniotic shunting. We identified 8 cases diagnosed with CCAM and only one case met the criteria for fetal surgery...
2016: Akusherstvo i Ginekologii︠a︡
Magdalena Litwińska, Ewelina Litwińska, Katarzyna Janiak, Anna Piaseczna-Piotrowska, Ewa Gulczyńska, Krzysztof Szaflik
OBJECTIVE: To evaluate the efficiency of thoracoamniotic shunts for drainage of macrocystic-type congenital cystic adenomatoid malformation (CCAM). SUBJECTS AND METHODS: This was a retrospective study of 12 fetuses with a large thoracic cyst treated with thoracoamniotic shunting between 2004 and 2014 in a tertiary fetal therapy center. Medline was searched to identify cases of CCAM treated with thoracoamniotic shunting. RESULTS: In all cases the thoracic cyst was associated with major mediastinal shift, the CCAM volume ratio (CVR) was >1...
August 5, 2016: Fetal Diagnosis and Therapy
Tatsuo Kuroda, Eiji Nishijima, Kosaku Maeda, Yasusih Fuchimoto, Seiichi Hirobe, Yuko Tazuke, Toshihiko Watanabe, Noriaki Usui
PURPOSE: The current study aimed to assess the perinatal risk and clinical features of congenital cystic lung diseases (CCLD). MATERIALS AND METHODS: Of the 874 CCLD patients identified in a nationwide survey, 428 patients born between 1992 and 2012 and treated at 10 high-volume centers, were retrospectively reviewed. RESULTS: Fetal hydrops was visualized using MRI in 9.2 % of the patients. Prenatal interventions were described for 221 of the 428 patients, including the maternal administration of steroid and pleuro-amniotic shunting...
September 2016: Pediatric Surgery International
I Rouillon, M Parodi, F Denoyelle, N Loundon
The diagnosis of hearing loss, especially in the context of newborn hearing screening, is mostly based on auditory brainstem response (ABR). According to the official CCAM nomenclature, ABR consists of recording early auditory evoked potentials to detect thresholds, study conduction times and measure amplitudes (corresponding to codes CDQP006 when performed without general anesthesia, and CDQP014 when performed with general anesthesia). ABR must be rigorously performed and interpreted, always in combination with a complete ENT examination and behavioral audiometry as soon as possible...
July 21, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Arianna Casagrande, Federica Pederiva
INTRODUCTION: The appropriate management of asymptomatic congenital pulmonary malformations (CPMs) remains controversial. Prophylactic surgery is recommended to avoid the risk for development of pulmonary infections and to prevent the highly debated development of malignancy. However, the true risk for development of malignancy remains unknown. A systematic review analyzed all cases in which lung tumors associated with CPMs in both the pediatric and adult populations were described...
July 15, 2016: Journal of Thoracic Oncology
Bo Xia, Gang Yu, Cuifen Liu, Chun Hong, Jing Tang
OBJECTIVE: To summarize the experience drawn from treatment of fetus with congenital cystic adenomatoid malformation (CCAM). METHODS: This retrospective report has reviewed a clinical history of 115 patients with CCAM from September 2012 to June 2014. All cases were divided into two groups according to symptomatology: group A (n = 96, asymptomatic group) and group B (n = 19, symptomatic group). Major factors were compared between two groups. Numerical data were presented as the median (range)...
May 10, 2016: Journal of Maternal-fetal & Neonatal Medicine
Timothy J Barreiro, Lucas Henn, Sisham Ingnam, Michael Sypert
Congenital pulmonary airway malformation (CPAM), previously known as congenital cystic adenomatoid malformation (CCAM), is an inborn abnormality of the lower respiratory system. Most often diagnosed in the perinatal period, these anomalies usually present with tachypnea, cyanosis, and respiratory distress. However, rare cases are asymptomatic and undiagnosed until adulthood.
2016: Respiratory Medicine Case Reports
Luis Gorospe, Gemma María Muñoz-Molina, Ana María Ayala-Carbonero, María Ángeles Fernández-Méndez, Álvaro Arribas-Marcos, Patricia Castro-Acosta, Paola Arrieta, Isabel García-Gómez-Muriel, Carol Fernanda Gómez-Barbosa, Deisy Barrios-Barreto
PURPOSE: Congenital cystic adenomatoid malformation (CCAM) of the lung in adults is very rare. We aimed to evaluate the clinicoradiological features of adult patients with CCAM. METHODS: Adult patients diagnosed with CCAM were evaluated for clinicoradiological presentation and management. METHODS: Nine patients were diagnosed with CCAM (four were incidentally diagnosed on chest imaging). Most cases appeared on computed tomography as thin-walled multiseptated cystic lesions...
May 2016: Clinical Imaging
Sujeet M Chilkar, Venkat Leelakumar, Chakravarthy P Ranjani, Bharati Musthyala, Kotte Vs Narayana
Congenital cystic adenomatoid malformation (CCAM) is a rare, developmental, hamartomatous abnormality of the lung characterized by a cessation of normal bronchiolar maturation, resulting in cystic overgrowth of the terminal bronchioles. We report one such case of CCAM in a 5-month-old female infant who was in perfect health until she suffered from spontaneous pyopneumothorax with type III CCAM of the lung and recovered after lobectomy.
March 2016: Lung India: Official Organ of Indian Chest Society
Prithviraj Nandigrami, John J Portman
Calmodulin (CaM) is a ubiquitous Ca(2+)-binding protein consisting of two structurally similar domains with distinct stabilities, binding affinities, and flexibilities. We present coarse grained simulations that suggest that the mechanism for the domain's allosteric transitions between the open and closed conformations depends on subtle differences in the folded state topology of the two domains. Throughout a wide temperature range, the simulated transition mechanism of the N-terminal domain (nCaM) follows a two-state transition mechanism while domain opening in the C-terminal domain (cCaM) involves unfolding and refolding of the tertiary structure...
March 14, 2016: Journal of Chemical Physics
Ernani B da Rosa, Daniélle B Silveira, Laís G Tsugami, Nathan L Bellé, Izabelle O Matos, Luciano V Targa, Rosilene da S Betat, André C da Cunha, Rolando A R Villacis, Sílvia R Rogatto, Luiza E Dorfman, Rafael F M Rosa, Paulo R G Zen
BACKGROUND: Nasoethmoidal meningocele is considered an uncommon type of cephalocele, and congenital cystic adenomatoid malformation (CCAM) is a rare lung disorder characterized by overgrowth of the terminal bronchioles. CASE: We report the unusual association between a nasoethmoidal meningocele and CCAM type II in a fetus exposed to valproic acid and misoprostol. The mother was an 18-year-old woman on her first pregnancy. She had a history of absence seizures since she was 5 years old...
April 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
Zhi Li, Ming Zhu, Suzhen Dong, Zhiqin Luo, Zhenghua Fei, Xiangming Fang, Linghong Qi
OBJECTIVE: To investigate the clinical value of prenatal MRI in the diagnosis and differential diagnosis of congenital bronchopulmonary sequestration (BPS). METHODS: From January 2009 to December 2014, 16 fetuses with BPS were diagnosed by fetal MRI in Huzhou Maternity and Child Care Hospital and Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine. The clinical data of these cases were analyzed retrospectively. All were singleton pregnancy, and MRI was carried out within 24-48 hours after routine prenatal ultrasound...
January 2016: Zhonghua Fu Chan Ke za Zhi
So Hyun Nam, Min Jeong Cho, Dae Yeon Kim
PURPOSE: The aim of this study is to present our experience with minimally invasive surgery (MIS) for congenital cystic adenomatoid malformations (CCAMs). METHODS: The medical records of infants under 2 years of age who underwent operation for a CCAM from 2009 to 2014 were retrospectively reviewed. RESULTS: MIS (9 of thoracoscopy and 1 of laparoscopy) was performed for 10 infants (male:female = 7:3) with CCAM. CCAM were discovered prenatally around gestational age of 24...
February 2016: Annals of Surgical Treatment and Research
T Forzini, E Alezra, M Demailly, E Lewandowski, F Saint
OBJECTIVE: The varicocele is a venous abnormality frequently found in humans (1/10). Although the recommendations for management of this pathology are clear, two therapeutic options can be discussed: surgery or radiological embolisation. We wanted to study the evolution of the therapeutic management of varicocele using the French national coding database. METHODS: Analysis of database from the "Agence technique de l'information sur l'hospitalisation" (ATIH) (number of surgical procedures and interventional radiology used in the treatment of varicocele for the period 2006-2014)...
March 2016: Progrès en Urologie
Alice Rebelo de Matos Borges Dos Reis, Frederico Becker Ribeiro, Regina Schultz
Congenital cystic adenomatoid malformation (CCAM) is an hamartomatous congenital pulmonary airway malformation with incidence ranging between 1:10,000 and 1:35,000 newborns. Currently CCAM is classified into five groups according to clinical and pathological features. The clinical outcome varies depending on the subtype and the extent of involvement. The authors report the case of a premature male newborn with the prenatal diagnosis of CCAM Type 1 associated with cardiac right axis deviation, who died 67 hours after birth due to respiratory failure...
July 2015: Autopsy & case reports
Taizo Furukawa, Osamu Kimura, Kouhei Sakai, Mayumi Higashi, Shigehisa Fumino, Shigeyoshi Aoi, Tatsuro Tajiri
BACKGROUND: The aim of this study was to assess surgical intervention strategies for congenital cystic lesions of the lungs (CCL), focusing on the safety of lung resection. MATERIALS AND METHODS: The clinical features of 27 children (CCAM, n=16; bronchial atresia, n=4; bronchogenic cyst, n=3; pulmonary sequestration, n=3; lobar emphysema, n=1) who were treated at our institution between 1995 and 2014 were analyzed. RESULTS: Of the 27 patients, 14 were asymptomatic, and 13 were symptomatic...
December 2015: Journal of Pediatric Surgery
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