keyword
MENU ▼
Read by QxMD icon Read
search

laryngeal tumor

keyword
https://www.readbyqxmd.com/read/29054457/bilateral-vocal-cord-immobility-resulting-from-cytomegalovirus-pharyngitis-a-case-report
#1
Rumi Ueha, Takaharu Nito, Takao Goto, Taku Sato, Tetsuo Ushiku, Tatsuya Yamasoba
Human cytomegalovirus (CMV) is an infectious herpes virus present in approximately 50% of the world's population. Pharyngitis is an uncommon manifestation of CMV infection, and vocal cord immobility (VCI) following CMV pharyngitis is quite rare. An 83-year-old man with well-controlled diabetes mellitus and hypertension was admitted due to dyspnea, odynophagia, and dysphagia. Laryngeal fiberscopy revealed bilateral vocal cords almost fixed at the median position, with mucosal redness, swelling, and edema at the hypopharyngeal area...
October 17, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29054118/efficacy-of-laryngectomy-alone-for-treatment-of-locally-advanced-laryngeal-cancer-a-stage-and-subsite-specific-survival-analysis
#2
Brian P Cervenka, Shyam Rao, D Gregory Farwell, Arnaud F Bewley
OBJECTIVE: Total laryngectomy is a well-established treatment for locally advanced laryngeal cancer. Evidence for the benefit of post-operative radiotherapy after laryngectomy in patients with locally advanced primaries and N0 or N1 nodal disease is limited. This study aims to determine whether total laryngectomy alone is adequate therapy for certain patient subgroups with locally advanced laryngeal cancer. DESIGN: We performed a retrospective survival analysis of patients in the surveillance epidemiology and end results (SEER) database with locally advanced laryngeal cancer between 2004-2012...
October 20, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29050230/a-potential-panel-of-two-long-non-coding-rna-signature-to-predict-recurrence-of-patients-with-laryngeal-cancer
#3
Zhigang Bai, Enhong Shi, Qiwei Wang, Zhouwei Dong, Ping Xu
Accumulating evidence has shown that aberrant lncRNA expression plays an oncogenic or tumor-suppressive role in the tumorigenesis of laryngeal cancer. However, the prognostic roles of lncRNAs in laryngeal cancer recurrence are still poorly understood. In this study, we obtained lncRNA expression profiles of 109 patients with laryngeal cancer by mining previously published gene expression microarray data from the Gene Expression Omnibus (GEO) and identified two lncRNAs associated with laryngeal cancer recurrence in the training dataset by using Cox regression analysis...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29049342/association-between-a-mirna-146a-polymorphism-and-susceptibility-to-head-and-neck-squamous-cell-carcinoma-in-chinese-patients-a-meta-analysis-of-8-case-control-studies
#4
Silin Zhang, Fangling Hu, Hongxing Liang, Yuanzhou Liu, Jianqiang Yang, Wensheng Zhou
A closer association has been found between the microRNA-146a rs2910164 polymorphism and the risk of head and neck carcinoma in some molecular epidemiological studies. Recently two meta-analyses were performed to explore the relationship between miRNA-146a polymorphisms and the susceptibility of squamous cell carcinoma of the head and neck (SCCHN); however, they yielded conflicting results in susceptibility regarding ethnic variations. Hence, the present study was performed to explain the relationship between the miRNA-146a rs2910164 polymorphism and the risk of SCCHN development of Chinese patients...
2017: PloS One
https://www.readbyqxmd.com/read/29048627/slc7a11-a-component-of-cysteine-glutamate-transporter-is-a-novel-biomarker-for-the-diagnosis-and-prognosis-in-laryngeal-squamous-cell-carcinoma
#5
Zhihong Ma, Hong Zhang, Meng Lian, Changli Yue, Gehong Dong, Yulan Jin, Rui Li, Hongfei Wan, Ru Wang, Ying Wang, Jie Zhai, Hongzhi Ma, Ling Feng, Jianfeng Han, Shuzhou Liu, Youxin Guo, Jianhua Li, Yu Liu, Jugao Fang, Honggang Liu
Solute carrier family 7, membrane 11 (SLC7A11) or (xCT) is a component of the cysteine-glutamate transporter, which plays a critical role in glutathione homeostasis which is important to protect cells from oxidative stress. SLC7A11 is distributed in various tissues and participates in the occurrence of a number of diseases, particularly in the pathogenesis of malignant tumors, but its role in laryngeal cancer development has not yet been clearly defined. The objective of the present study was to investigate the role of SLC7A11 in laryngeal squamous cell carcinoma (LSCC)...
September 20, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29046798/monitoring-of-recurrent-and-superior-laryngeal-nerve-function-using-an-airwayscope%C3%A2-during-thyroid-surgery
#6
Kei Ijichi, Hiroshi Sasano, Megumi Harima, Shingo Murakami
In thyroid surgery, intraoperative identification and preservation of the recurrent laryngeal nerve (RLN) and superior laryngeal nerve external branch (SLNEB) are crucial. Several reports have proposed that electromyography (EMG) monitoring is an acceptable adjunct for identification and preservation of the RLN. However, a limited number of hospitals have access to an EMG monitoring system. Therefore, the development of another viable monitoring method is required. The aim of the present study was to design a new RLN and SLNEB monitoring method combining an Airwayscope™ (AWS) and a facial nerve stimulator...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29043013/mir-125a-suppresses-viability-and-glycolysis-and-induces-apoptosis-by-targeting-hexokinase-2-in-laryngeal-squamous-cell-carcinoma
#7
Zhanwei Sun, Wenqi Zhang, Qian Li
BACKGROUND: miR-125a usually functions as a tumor suppressor in cancers. However, the role of miR-125a in laryngeal squamous cell carcinoma (LSCC) has not been determined. METHODS: qRT-PCR was applied to measure the expression of miR-125a and HK2 mRNA in LSCC tissues and cells. CCK-8 kit and flow cytometry analysis were performed to detect cell viability and apoptosis. Luciferase reporter assay and RNA immunoprecipitation (RIP) were conducted to confirm the relationship between miR-125a and HK2...
2017: Cell & Bioscience
https://www.readbyqxmd.com/read/29039258/diagnosis-and-treatment-of-laryngeal-schwannoma-a-systematic-review
#8
Michele Tulli, Stefano Bondi, Chanel Elisha Smart, Leone Giordano, Matteo Trimarchi, Andrea Galli, Davide Di Santo, Matteo Biafora, Mario Bussi
Objective This review summarizes the clinical features, diagnostic workup, and surgical treatment of laryngeal schwannoma with the aim of providing guidance for the management of this rare disease. The collated data allowed the statistical testing of several hypotheses, including the efficacy of endoscopic vs open surgical intervention and the usefulness of preoperative biopsy. Data Sources PubMed, Google Scholar, Cochrane, and SCOPUS. Review Methods Basic epidemiological and clinical presentation data were collated together with details of diagnostic image modality, lesion attributes, and the use of preoperative biopsy...
October 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29034342/p16-ink4a-expression-in-invasive-laryngeal-cancer
#9
Brenda Y Hernandez, Mobeen Rahman, Charles F Lynch, Wendy Cozen, Elizabeth R Unger, Martin Steinau, Trevor Thompson, Maria Sibug Saber, Sean F Altekruse, Marc T Goodman, Amy Powers, Christopher Lyu, Mona Saraiya
We examined p16 expression in tumors from a population-based sample of laryngeal cancer cases diagnosed in the U.S. Samples had been previously genotyped for HPV DNA. Overall, p16 expression was observed in laryngeal tissue from 8 of 101 (7.9%) cases. p16 expression was observed in 2 of 16 (12.5%) cases previously determined to be HPV DNA positive. The two cases dually positive for p16 and HPV DNA were non-keratinizing SCC and papillary SCC tumors that were positive for genotypes 18 and 35/89, respectively...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29027527/-laryngeal-paraganglioma
#10
S D Bezhanova, R A Khasanov, A I Pavlovskaya, E A Smirnova
The paper describes a clinical case of laryngeal paraganglioma, a rare tumor. It provides the detailed characteristics of current diagnostic techniques.
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28988411/how-reliably-can-computed-tomography-predict-thyroid-invasion-prior-to-laryngectomy
#11
Andrew S Harris, Carl D Passant, Duncan R Ingrams
OBJECTIVES/HYPOTHESIS: There is little evidence to support the removal of thyroid tissue during total laryngectomy. Although oncological control of the tumor is the priority, thyroidectomy can lead to hypothyroidism and hypoparathyroidism. This study aimed to test the usefulness of preoperative computed tomography in predicting histological invasion of the thyroid. STUDY DESIGN: Ambispective cohort study. METHODS: All patients undergoing total laryngectomy for squamous cell carcinoma at one center from 2006 to 2016 were included...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28982865/deregulation-of-pten-expression-in-laryngeal-squamous-cell-carcinoma-based-on-tissue-microarray-digital-analysis
#12
Nicholas S Mastronikolis, Evangelos Tsiambas, Theodoros A Papadas, Andreas Karameris, Vasileios Ragos, Dimitrios Peschos, Stylianos N Mastronikolis, Athanasios T Papadas, Christos Liatsos, Ilianna E Armata, Panagiotis P Fotiades
BACKGROUND/AIM: Phosphatase and tensin homolog (PTEN) (gene locus: 10q23.3) -a tumor suppressor gene- is deleted, mutated or epigenetically hyper-methylated in a variety of malignancies. PTEN acts as a negative regulator in PI3K/AKT/mTOR signaling transduction pathway. Our aim was to investigate PTEN protein expression patterns in laryngeal squamous cell carcinomas (LSCC). MATERIALS AND METHODS: Using tissue microarray technology, fifty (n=50) primary LSCCs were cored and re-embedded into one recipient block...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28979140/predictive-factors-and-prognosis-for-recurrent-laryngeal-nerve-invasion-in-papillary-thyroid-carcinoma
#13
Wenjie Chen, Jianyong Lei, Jiaying You, Yali Lei, Zhihui Li, Rixiang Gong, Huairong Tang, Jingqiang Zhu
BACKGROUND: Recurrent laryngeal nerve (RLN) invasion in papillary thyroid carcinoma (PTC) is one of the main predictors of poor prognosis. The present study investigated the risk factors for RLN invasion in PTC patients. METHODS: A total of 3,236 patients who received thyroidectomy due to PTC in Thyroid and Parathyroid Surgery Center of West China Hospital of Sichuan University were reviewed. Demographics and clinical factors, imaging examination (ultrasonography) characteristics, surgical details, postoperative pathological details, recurrence, and postoperative complications were recorded...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28977096/pegylated-interferon-for-treating-severe-recurrent-respiratory-papillomatosis-in-a-child-case-report
#14
Rebecca Maunsell, Maria Angela Bellomo-Brandão
CONTEXT: Recurrent respiratory papillomatosis (RRP) is the most common laryngeal tumor. During childhood, it may present in extremely severe forms defined by the need for frequent surgical procedures to relieve respiratory distress and/or involvement of extralaryngeal sites such as lung involvement. Adjuvant therapies are indicated in these cases and interferon is one of the options. Pegylated interferon is more effective than conventional alpha interferon and, given its reported results in relation to treating hepatitis C over the past decade, we hypothesized that this might be more effective than conventional interferon also for treating respiratory papillomatosis...
September 18, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28976011/oncologic-results-and-quality-of-life-in-patients-with-squamous-cell-carcinoma-of-hypopharynx-after-transoral-laser-microsurgery
#15
Li-Ting Hung, Hsin-I Huang, Ling-Wei Wang, Muh-Hwa Yang, Pen-Yuan Chu
OBJECTIVE: Transoral laser microsurgery (TLM) is an alternative method for organ preservation in squamous cell carcinoma of hypopharynx (HPSCC). The purpose of this study was to analyze the oncologic results and quality of life (QOL) in HPSCC patients after TLM. METHODS: Forty-six patients who underwent TLM were included, 34 of them had QOL evaluations. The QOL analyses were measured with EORTC QLQ-C-30, QLQ-H&N35, VHI-30, and MDADI at least 6 months postoperatively...
October 4, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28973501/chemo-selection-with-docetaxel-cisplatin-and-5-fluorouracil-tpf-regimen-followed-by-radiation-therapy-or-surgery-for-pharyngeal-and-laryngeal-carcinoma
#16
Takuma Matoba, Kei Ijichi, Takeshi Yanagi, Kayoko Kabaya, Daisuke Kawakita, Shintaro Beppu, Junichi Torii, Shingo Murakami
Background: Induction chemotherapy for patients with head and neck cancer is widely performed, and several advantages of induction chemotherapy have been reported. However, there is currently insufficient evidence to strongly recommend induction chemotherapy. In this study, we analyzed the outcomes for patients treated with induction chemotherapy and subsequent definitive treatments. Methods: Operable patients with untreated oropharyngeal, hypopharyngeal and laryngeal squamous cell carcinoma treated with induction chemotherapy were included in this retrospective study...
August 18, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28971654/-surgical-treatment-of-locally-advanced-well-differentiated-thyroid-carcinoma
#17
Shorook Na'ara, Moran Amit, Salem Billan, Jacob Cohen, Ziv Gil
AIMS: We aimed to better define the most appropriate therapeutic protocol for this type of tumor. BACKGROUND: The incidence of well-differentiated thyroid carcinoma is rising and the mortality from the disease remains low for patients with early disease. Nevertheless, the survival of patients with advanced disease has not improved during the last four decades and a controversy still exists in the literature regarding the optimal treatment in patients with locally advanced (T4) differentiated thyroid carcinoma...
September 2017: Harefuah
https://www.readbyqxmd.com/read/28964599/-a-rare-endolaryngeal-tumor
#18
Carine Ngo, Sébastien Albert, Beatrix Barry, Christiane Copie-Bergman, Anne Couvelard, Muriel Hourseau
We report the case of a 65-year-old woman who presented with a dysphonia. ENT tomography and laryngoscopy showed an endolaryngeal tumoral lesion extended to the right supraglottis. Biopsy of the lesion revealed dense lymphoid infiltrate in the lamina propria, without necrosis or ulceration of the mucosa. The infiltrate showed many CD3+, CD5+, CD4+, CD8+ lymphocytes and plasmocytes. Larger lymphoid cells with cytologic atypia expressed CD56 and cytotoxicity markers such as TIA1 and granzyme B. In situ hybridization for EBV revealed numerous positive cells...
September 27, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28964387/-resection-of-recurrent-neck-cancers-with-replacement-of-the-carotid-artery
#19
J-B Ricco, G Illuminati, R Belmonte
OBJECTIVES: The management of patients with recurrent neck cancer invading the carotid artery is controversial. The aim of this study was to evaluate the overall survival and healthy survival years (QALY) as well as the patency of carotid revascularization after enbloc tumor resection followed by complementary radiotherapy. METHODS: From 2000 to 2016, 42 consecutive patients with recurrent neck cancer invading the carotid artery underwent resection of the tumor associated with reconstruction of the carotid artery with a PTFE prosthesis (n=31) or with a saphenous vein graft (n=11)...
October 2017: J Med Vasc
https://www.readbyqxmd.com/read/28960661/management-of-paratracheal-lymph-nodes-in-laryngeal-cancer-with-subglottic-involvement
#20
Marco Lucioni, Luca D'Ascanio, Elena De Nardi, Marco Lionello, Andy Bertolin, Giuseppe Rizzotto
BACKGROUND: The purpose of this study was to present our findings on the involvement of paratracheal lymph nodes in laryngeal squamous cell carcinoma (SCC) with subglottis extension, which is controversial. METHODS: We assessed 196 patients with laryngeal SCC involving the subglottis, treated with open laryngeal surgery with or without paratracheal neck dissection (PTND). The relationship of the paratracheal lymph node metastatic pattern with laterocervical nodal status and tumor location within different subglottic subsites was analyzed...
September 27, 2017: Head & Neck
keyword
keyword
57589
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"