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https://www.readbyqxmd.com/read/28103143/video-assisted-thoracic-surgical-lobectomy-for-lung-cancer-description-of-a-learning-curve
#1
Fei Yao, Jian Wang, Ju Yao, Fangrong Hang, Shiqi Cao, Yongke Cao
BACKGROUND: Video-assisted thoracic surgical (VATS) lobectomy is gaining popularity in the treatment of lung cancer. The aim of this study is to investigate the learning curve of VATS lobectomy by using multidimensional methods and to compare the learning curve groups with respect to perioperative clinical outcomes. METHODS: We retrospectively reviewed a prospective database to identify 67 consecutive patients who underwent VATS lobectomy for lung cancer by a single surgeon...
January 19, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28102005/blind-prediction-of-deleterious-amino-acid-variations-with-snps-go
#2
Emidio Capriotti, Pier Luigi Martelli, Piero Fariselli, Rita Casadio
: SNPs&GO is a machine learning method for predicting the association of single amino acid variations (SAVs) to disease, considering protein functional annotation. The method is a binary classifier that implements a Support Vector Machine algorithm to discriminate between disease-related and neutral SAVs. SNPs&GO combines information from protein sequence with functional annotation encoded by Gene Ontology terms. Tested in sequence mode on more than 38,000 SAVs from the SwissVar dataset, our method reached 81% overall accuracy and an area under the receiving operating characteristic curve (AUC) of 0...
January 19, 2017: Human Mutation
https://www.readbyqxmd.com/read/28101451/laparoscopic-vs-open-donor-nephrectomy-lessons-learnt-from-single-academic-center-experience
#3
Georgios Tsoulfas, Polyxeni Agorastou, Dicken S C Ko, Martin Hertl, Nahel Elias, A B Cosimi, Tatsuo Kawai
AIM: To compare laparoscopic and open living donor nephrectomy, based on the results from a single center during a decade. METHODS: This is a retrospective review of all living donor nephrectomies performed at the Massachusetts General Hospital, Harvard Medical School, Boston, between 1/1998 - 12/2009. Overall there were 490 living donors, with 279 undergoing laparoscopic living donor nephrectomy (LLDN) and 211 undergoing open donor nephrectomy (OLDN). Demographic data, operating room time, the effect of the learning curve, the number of conversions from laparoscopic to open surgery, donor preoperative glomerular filtration rate and creatinine (Cr), donor and recipient postoperative Cr, delayed graft function and donor complications were analyzed...
January 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28099700/a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-comparing-hysteroscopic-morcellation-with-resectoscopy-for-patients-with-endometrial-lesions
#4
REVIEW
Chunbo Li, Zhiyuan Dai, Yuping Gong, Bingying Xie, Bei Wang
BACKGROUND: Results on the efficacy of hysteroscopic morcellation for patients with endometrial lesions remain conflicting. OBJECTIVES: To compare hysteroscopic morcellation with conventional resectoscopy for removal of endometrial lesions. SEARCH STRATEGY: Electronic databases were searched for reports published up to February 1, 2016, using terms such as "morcellator," "morcellators," "morcellate," "morcellation," "morcellated," "hysteroscopy," "hysteroscopy," "uteroscope," and "transcervical...
January 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28099055/mastering-robotic-surgery-where-does-the-learning-curve-lead-us
#5
Ciro Andolfi, Konstantin Umanskiy
The robotic surgical technology introduced over the last decade and a half has revolutionized many aspects of performing complex procedures. It combines technological and clinical innovations to improve surgical quality and patient outcomes. Yet, to date, there is still a lack of standardization in training and certification of robotic surgeons. The criteria for proficiency and credentialing in robotic surgery vary widely among institutions. The aim of this review is to discuss the key points of training and surgeon assessment in robotic surgery, as well as the challenges that still need to be overcome...
January 18, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28097262/lessons-learned-over-a-decade-of-pediatric-robotic-ureteral-reimplantation
#6
REVIEW
Minki Baek, Chester J Koh
The da Vinci robotic system has improved surgeon dexterity, ergonomics, and visualization to allow for a minimally invasive option for complex reconstructive procedures in children. Over the past decade, robot-assisted laparoscopic ureteral reimplantation (RALUR) has become a viable minimally invasive surgical option for pediatric vesicoureteral reflux (VUR). However, higher-than-expected complication rates and suboptimal reflux resolution rates at some centers have also been reported. The heterogeneity of surgical outcomes may arise from the inherent and underestimated complexity of the RALUR procedure that may justify its reclassification as a complex reconstructive procedure and especially for robotic surgeons early in their learning curve...
January 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28096747/implementing-a-3d-printing-service-in-a-biomedical-library
#7
Verma Walker
Three-dimensional (3D) printing is opening new opportunities in biomedicine by enabling creative problem solving, faster prototyping of ideas, advances in tissue engineering, and customized patient solutions. The National Institutes of Health (NIH) Library purchased a Makerbot Replicator 2 3D printer to give scientists a chance to try out this technology. To launch the service, the library offered training, conducted a survey on service model preferences, and tracked usage and class attendance. 3D printing was very popular, with new lab equipment prototypes being the most common model type...
January 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28095003/cocaine-addiction-as-a-homeostatic-reinforcement-learning-disorder
#8
Mehdi Keramati, Audrey Durand, Paul Girardeau, Boris Gutkin, Serge H Ahmed
Drug addiction implicates both reward learning and homeostatic regulation mechanisms of the brain. This has stimulated 2 partially successful theoretical perspectives on addiction. Many important aspects of addiction, however, remain to be explained within a single, unified framework that integrates the 2 mechanisms. Building upon a recently developed homeostatic reinforcement learning theory, the authors focus on a key transition stage of addiction that is well modeled in animals, escalation of drug use, and propose a computational theory of cocaine addiction where cocaine reinforces behavior due to its rapid homeostatic corrective effect, whereas its chronic use induces slow and long-lasting changes in homeostatic setpoint...
January 16, 2017: Psychological Review
https://www.readbyqxmd.com/read/28094850/discriminating-solitary-cysts-from-soft-tissue-lesions-in-mammography-using-a-pretrained-deep-convolutional-neural-network
#9
Thijs Kooi, Bram van Ginneken, Nico Karssemeijer, Ard den Heeten
PURPOSE: It is estimated that 7% of women in the western world will develop palpable breast cysts in their lifetime. Even though cysts have been correlated with risk of developing breast cancer, many of them are benign and do not require follow-up. We develop a method to discriminate benign solitary cysts from malignant masses in digital mammography. We think a system like this can have merit in the clinic as a decision aid or complementary to specialised modalities. METHODS: We employ a deep Convolutional Neural Network (CNN) to classify cyst and mass patches...
January 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28094425/learning-curve-in-anatomo-electrophysiological-correlations-in-subthalamic-nucleus-stimulation
#10
Dušan Hrabovsky, Marek Balaz, Martina Bockova, Věra Feitova, Zdeněk Novak, Jan Chrastina
AIM: Advances in neuroradiological planning techniques in deep brain stimulation put the need for intraoperative electrophysiological monitoring into doubt. Moreover intraoperative monitoring prolongs surgical time and there is potential association between the use of microelectrodes and increased incidence of hemorrhagic complications Material and Methods: The study analyzes the correlation between the anatomically planned trajectory and the final subthalamic electrode placement after electrophysiological monitoring in patients with Parkinson's disease and its change with the increasing experience of the surgical team...
December 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28094412/ultrasound-guided-approach-to-the-cervical-articular-process-joints-in-horses-a-validation-of-the-technique-in-cadavers
#11
Jessica Purefoy Johnson, John David Stack, Conor Rowan, Ian Handel, John Mark O'Leary
OBJECTIVES: To compare accuracy of the ultrasound-guided craniodorsal (CrD) approach with the dorsal (D) approach to the cervical articular process joints, and to evaluate the effect of transducer, needle gauge, and operator experience. METHODS: Cervical articular process joints from 14 cadaveric neck specimens were injected using either a D or CrD approach, a linear (13 MHx) or microconvex transducer (10 MHz), and an 18 or 20 gauge needle, by an experienced or inexperienced operator...
January 17, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28092203/machine-learning-of-three-dimensional-right-ventricular-motion-enables-outcome-prediction-in-pulmonary-hypertension-a-cardiac-mr-imaging-study
#12
Timothy J W Dawes, Antonio de Marvao, Wenzhe Shi, Tristan Fletcher, Geoffrey M J Watson, John Wharton, Christopher J Rhodes, Luke S G E Howard, J Simon R Gibbs, Daniel Rueckert, Stuart A Cook, Martin R Wilkins, Declan P O'Regan
Purpose To determine if patient survival and mechanisms of right ventricular failure in pulmonary hypertension could be predicted by using supervised machine learning of three-dimensional patterns of systolic cardiac motion. Materials and Methods The study was approved by a research ethics committee, and participants gave written informed consent. Two hundred fifty-six patients (143 women; mean age ± standard deviation, 63 years ± 17) with newly diagnosed pulmonary hypertension underwent cardiac magnetic resonance (MR) imaging, right-sided heart catheterization, and 6-minute walk testing with a median follow-up of 4...
January 16, 2017: Radiology
https://www.readbyqxmd.com/read/28091694/-evidence-based-tep-technique
#13
F Köckerling
The guidelines of all international hernia societies recommend as procedures of choice the laparoendoscopic techniques total extraperitoneal patch plasty (TEP) and transabdominal preperitoneal patch plasty (TAPP) as well as the open Lichtenstein operation for elective inguinal hernia repair. The learning curve associated with the laparoendoscopic techniques, in particular TEP, is longer than that for the open Lichtenstein technique due to the complexity of the procedures. Accordingly, for laparoendoscopic techniques it is particularly important that the operations are conducted in a standardized manner in compliance with the evidence-based recommendations given for the technical details...
January 13, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28089473/box-or-virtual-reality-trainer-which-tool-results-in-better-transfer-of-laparoscopic-basic-skills-a-prospective-randomized-trial
#14
Christian Brinkmann, Mathias Fritz, Ulrich Pankratius, Ralf Bahde, Philipp Neumann, Steffen Schlueter, Norbert Senninger, Emile Rijcken
OBJECTIVE: Simulation training improves laparoscopic performance. Laparoscopic basic skills can be learned in simulators as box- or virtual-reality (VR) trainers. However, there is no clear recommendation for either box or VR trainers as the most appropriate tool for the transfer of acquired laparoscopic basic skills into a surgical procedure. DESIGN: Both training tools were compared, using validated and well-established curricula in the acquirement of basic skills, in a prospective randomized trial in a 5-day structured laparoscopic training course...
January 12, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28089438/a-retrospective-comparison-of-biliopancreatic-diversion-with-duodenal-switch-with-single-anastomosis-duodenal-switch-sips-stomach-intestinal-pylorus-sparing-surgery-at-a-single-institution-with-two-year-follow-up
#15
Amit Surve, Hinali Zaveri, Daniel Cottam, LeGrand Belnap, Austin Cottam, Samuel Cottam
BACKGROUND: The traditional duodenal switch is performed using a Roux-en-Y configuration. This procedure has proven to be the most effective procedure for long-term weight loss and co-morbidity reduction. Recently, stomach intestinal pylorus sparing surgery (SIPS) has been introduced as a simpler and potentially safer variation of the duodenal switch (DS). It is a single anastomosis end-to-side proximal duodeno-ileal bypass with a sleeve gastrectomy. In this study, we compare our outcomes between biliopancreatic diversion with duodenal switch (BPD-DS) and SIPS at 2 years...
December 2, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28088426/propensity-matched-comparison-of-video-assisted-thoracoscopic-with-thoracotomy-lobectomy-for-locally-advanced-non-small-cell-lung-cancer
#16
Kezhong Chen, Xun Wang, Fan Yang, Jianfeng Li, Guanchao Jiang, Jun Liu, Jun Wang
OBJECTIVE: We evaluated whether video-assisted thoracoscopic lobectomy for locally advanced non-small cell lung cancer could be performed safely and with acceptable long-term outcomes by our improved technique and compared with standard thoracotomy lobectomy in a well-balanced population. METHODS: Patients with clinical stage II and III A non-small cell lung cancers who received lobectomy were reviewed. Video-assisted thoracoscopic lobectomies were all performed with Wang's technique by the surgeons who had overcome the learning curve and achieved proficiency...
December 15, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28088191/predicting-probable-alzheimer-s-disease-using-linguistic-deficits-and-biomarkers
#17
Sylvester O Orimaye, Jojo S-M Wong, Karen J Golden, Chee P Wong, Ireneous N Soyiri
BACKGROUND: The manual diagnosis of neurodegenerative disorders such as Alzheimer's disease (AD) and related Dementias has been a challenge. Currently, these disorders are diagnosed using specific clinical diagnostic criteria and neuropsychological examinations. The use of several Machine Learning algorithms to build automated diagnostic models using low-level linguistic features resulting from verbal utterances could aid diagnosis of patients with probable AD from a large population...
January 14, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28087159/the-direct-anterior-approach-for-complex-primary-total-hip-arthroplasty-the-extensile-acetabular-approach-on-a-regular-operating-room-table
#18
Ben Molenaers, Ronald Driesen, Guy Molenaers, Kristoff Corten
BACKGROUND: The direct anterior approach on a regular operating room table has been reported with low dislocation rates. This might be beneficial for complex primary total hip arthroplasty (THA) such as in patients with cerebral palsy or following femoral or pelvic osteotomies. Extending the approach is often required to overcome problems such as acetabular deformities or severe contractures. METHODS: We retrospectively evaluated the results and complications of 29 patients with 37 complex primary THA in which an extensile approach was used...
December 22, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28081584/-mini-open-approach-shows-good-results-in-treatment-of-femoroacetabular-impingement
#19
Stephanie Maria Kirschbaum, Frank Sitterlee, Carsten Perka, Michael Müller
Background Femoroacetabular impingement (FAI) describes a painful, abnormal (bony) contact between the femoral neck and acetabulum, which, if left untreated, contributes to early osteoarthritis (OA) of the hip. Despite its flat learning curve and long operation times, hip arthroscopy has been used increasingly often in recent years in the surgery of femoroacetabular impingement. The mini-open technique (MOT) offers a possible alternative that addresses the abnormal morphological prominence and allows minimally invasive clearance of hip motion...
January 12, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28081006/latent-feature-representation-with-depth-directional-long-term-recurrent-learning-for-breast-masses-in-digital-breast-tomosynthesis
#20
Dae Hoe Kim, Seong Tae Kim, Jung Min Chang, Yong Man Ro
Characterization of masses in computer-aided detection systems for digital breast tomosynthesis (DBT) is an important step to reduce false positive (FP) rates. To effectively differentiate masses from FPs in DBT, discriminative mass feature representation is required. In this paper, we propose a new latent feature representation boosted by depth directional long-term recurrent learning for characterizing malignant masses. The proposed network is designed to encode mass characteristics in two parts. First, 2D spatial image characteristics of DBT slices are encoded as a slice feature representation by convolutional neural network (CNN)...
February 7, 2017: Physics in Medicine and Biology
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