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https://www.readbyqxmd.com/read/29329025/the-midwifery-services-framework-the-process-of-implementation
#1
Andrea Nove, Nester T Moyo, Martha Bokosi, Shantanu Garg
In 2015, the International Confederation of Midwives launched the Midwifery Services Framework: a new evidence-based tool to guide countries through the process of improving their sexual, reproductive, maternal and newborn health services through strengthening and developing the midwifery workforce. The Midwifery Services Framework is aligned with key global architecture for sexual, reproductive, maternal and newborn health and human resources for health, and with the recommendations of the 2014 Lancet Series on Midwifery...
December 26, 2017: Midwifery
https://www.readbyqxmd.com/read/29325574/applied-global-health-diplomacy-profile-of-health-diplomats-accredited-to-the-united-states-and-foreign-governments
#2
Matthew D Brown, Julie N Bergmann, Thomas E Novotny, Tim K Mackey
BACKGROUND: Global health diplomacy (GHD) is a burgeoning field bridging the priorities of global health and foreign affairs. Given the increasing need to mobilize disparate global health stakeholders coupled with the need to design complex public health partnerships to tackle issues of international concern, effective and timely cooperation among state actors is critical. Health Attachés represent this coordination focal point and are key diplomatic professionals at the forefront of GHD...
January 11, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29321316/two-residues-in-nsp9-contribute-to-the-enhanced-replication-and-pathogenicity-of-highly-pathogenic-porcine-reproductive-and-respiratory-syndrome-virus
#3
Kuan Zhao, Jia-Cong Gao, Jun-Yao Xiong, Jin-Chao Guo, Yong-Bo Yang, Cheng-Gang Jiang, Yan-Dong Tang, Zhi-Jun Tian, Xue-Hui Cai, Guang-Zhi Tong, Tong-Qing An
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) possesses greater replicative capacity and pathogenicity than classical PRRSV. However, the factors that lead to enhanced replication and pathogenicity remain unclear. In our study, an alignment of all available full-length sequences of North-American type PRRSVs (n = 204) revealed two consistent amino acid mutations that differed between HP-PRRSV and classical PRRSV and were located at positions 519 and 544 in non-structural protein 9...
January 10, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29315118/characteristics-of-cervical-spine-motion-in-different-types-of-cervical-alignment-kinematic-mri-study
#4
Kittipong Sessumpun, Permsak Paholpak, Kevork N Hindoyan, Koji Tamai, Thananit Sangkomkamhang, Zorica Buser, Jeffrey C Wang
STUDY DESIGN: Retrospective study. OBJECTIVE: To evaluate how each type of sagittal cervical alignment affects the motion of the upper and subaxial cervical spine using kinematic magnetic resonance imaging. SUMMARY OF BACKGROUND DATA: The sagittal malalignment of the cervical spine from degeneration in the subaxial cervical spine reflects a disruption in the kinematic properties of the cervical spine and affects the motion of adjacent segments...
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29306921/building-a-high-quality-oncology-nursing-workforce-through-lifelong-learning-the-de-souza-model
#5
Mary Jane Esplen, Jiahui Wong, Esther Green, Joy Richards, Jane Li
AbstractCancer is one of the leading causes of death in the world. Along with increased new cases, cancer care has become increasingly complex due to advances in diagnostics and treatments, greater survival, and new models of palliative care. Nurses are a critical resource for cancer patients and their families. Their roles and responsibilities are expanding across the cancer care continuum, calling for specialized training and support. Formal education prepares nurses for entry level of practice, however, it does not provide the specialized competencies required for quality care of cancer patients...
January 5, 2018: International Journal of Nursing Education Scholarship
https://www.readbyqxmd.com/read/29304092/dipeptidyl-peptidase-3-a-novel-protease-from-leishmania-braziliensis
#6
Jenny R Diaz, Cesar A Ramírez, Paola A Nocua, Fanny Guzman, José M Requena, Concepción J Puerta
The increase of leishmaniasis cases worldwide and the emergence of Leishmania strains resistant to current treatments make necessary to find new therapeutic targets. Proteases are appealing drug targets because they play pivotal roles in facilitating parasite survival and promoting pathogenesis. Enzymes belonging to the dipeptidyl peptidase 3 (DPP3) group have been described in different organisms such as mammals, insects and yeast, in which these enzymes have been involved in both protein turnover and protection against oxidative damage...
2018: PloS One
https://www.readbyqxmd.com/read/29303956/do-nutrient-based-front-of-pack-labelling-schemes-support-or-undermine-food-based-dietary-guideline-recommendations-lessons-from-the-australian-health-star-rating-system
#7
Mark A Lawrence, Sarah Dickie, Julie L Woods
Food-based Dietary Guidelines (FBDGs) promote healthy dietary patterns. Nutrient-based Front-of-Pack Labelling (NBFOPL) schemes rate the 'healthiness' of individual foods. This study aimed to investigate whether the Australian Health Star Rating (HSR) system aligns with the Australian Dietary Guidelines (ADGs). The Mintel Global New Products Database was searched for every new food product displaying a HSR entering the Australian marketplace from 27 June 2014 (HSR system endorsement) until 30 June 2017. Foods were categorised as either a five food group (FFG) food or 'discretionary' food in accordance with ADG recommendations...
January 5, 2018: Nutrients
https://www.readbyqxmd.com/read/29301171/proximal-junctional-kyphosis-and-proximal-junctional-failure-following-adult-spinal-deformity-surgery
#8
REVIEW
Seung-Jae Hyun, Byoung Hun Lee, Jong-Hwa Park, Ki-Jeong Kim, Tae-Ahn Jahng, Hyun-Jib Kim
The purpose of this review is the current understanding of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity (ASD) surgery. We carried out a systematic search of PubMed for literatures published up to September 2017 with "proximal junctional kyphosis," "proximal junctional failure," and "adult spinal deformity" as search terms. A total of 98 literatures were searched. The 37 articles were included in this review. PJK is multifactorial in origin and likely results from variable risk factors...
December 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29299281/establishing-the-phylogeny-of-prochlorococcus-with-a-new-alignment-free-method
#9
Xin Zhao, Kun Tian, Rong L He, Stephen S-T Yau
Prochlorococcus marinus, one of the most abundant marine cyanobacteria in the global ocean, is classified into low-light (LL) and high-light (HL) adapted ecotypes. These two adapted ecotypes differ in their ecophysiological characteristics, especially whether adapted for growth at high-light or low-light intensities. However, some evolutionary relationships of Prochlorococcus phylogeny remain to be resolved, such as whether the strains SS120 and MIT9211 form a monophyletic group. We use the Natural Vector (NV) method to represent the sequence in order to identify the phylogeny of the Prochlorococcus...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29297279/cufid-query-accurate-network-querying-through-random-walk-based-network-flow-estimation
#10
Hyundoo Jeong, Xiaoning Qian, Byung-Jun Yoon
BACKGROUND: Functional modules in biological networks consist of numerous biomolecules and their complicated interactions. Recent studies have shown that biomolecules in a functional module tend to have similar interaction patterns and that such modules are often conserved across biological networks of different species. As a result, such conserved functional modules can be identified through comparative analysis of biological networks. RESULTS: In this work, we propose a novel network querying algorithm based on the CUFID (Comparative network analysis Using the steady-state network Flow to IDentify orthologous proteins) framework combined with an efficient seed-and-extension approach...
December 28, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29288722/comparative-analysis-of-phosphoethanolamine-transferases-involved-in-polymyxin-resistance-across-ten-clinically-relevant-gram-negative-bacteria
#11
Jiayuan Huang, Yan Zhu, Meiling Han, Mengyao Li, Jiangning Song, Tony Velkov, Chen Li, Jian Li
The rapid emergence of Gram-negative 'superbugs' has become a significant threat to human health globally and polymyxins become a last-line therapy for these very problematic pathogens. Polymyxins exhibit their antibacterial killing by the initial interaction with lipid A in Gram-negative bacteria. Polymyxin resistance can be mediated by phosphoethanolamine (PEA) modification of lipid A that abolishes the initial electrostatic interaction with polymyxins. Both chromosome-encoded (e.g. EptA, EptB and EptC) and plasmid-encoded PEA transferases (e...
December 27, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29288132/cochrane-systematic-reviews-of-interventions-for-risk-factors-correlate-weakly-with-global-risk-factor-burden-a-cross-sectional-study
#12
David J Roberts, John Cafferkey, Emma Plugge
BACKGROUND: Systematic reviews (SRs) are important for healthcare decision makers requiring evidence for interventions that target modifiable risk factors to prevent disease. We investigated whether Cochrane SR output correlated with risk factor burden as assessed by the Global Burden of Disease Study 2015. METHODS: We screened and extracted data from Cochrane reviews and protocols published since January 2011 investigating modifiable risk factors as outcomes. We calculated Spearman's rank correlation between the number of occasions a risk factor was a SR outcome and that risk factor's global disease burden in DALYs...
December 26, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29284445/mapping-standard-ophthalmic-outcome-sets-to-metrics-currently-reported-in-eight-eye-hospitals
#13
Monica Michelotti, Dirk F de Korne, Jennifer S Weizer, Paul P Lee, Declan Flanagan, Simon P Kelly, Anne Odergren, Sukhpal S Sandhu, Charity Wai, Niek Klazinga, Aravind Haripriya, Joshua D Stein, Melanie Hingorani
BACKGROUND: To determine alignment of proposed international standard outcomes sets for ophthalmic conditions to metrics currently reported by eye hospitals. METHODS: Mixed methods comparative benchmark study, including eight eye hospitals in Australia, India, Singapore, Sweden, U.K., and U.S. All are major international tertiary care and training centers in ophthalmology. Main outcome measure is consistency of ophthalmic outcomes measures reported. RESULTS: International agreed standard outcomes (ICHOM) sets are available for cataract surgery (10 metrics) and macular degeneration (7 metrics)...
December 29, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29282045/balancing-the-local-and-the-universal-in-maintaining-ethical-access-to-a-genomics-biobank
#14
Catherine Heeney, Shona M Kerr
BACKGROUND: Issues of balancing data accessibility with ethical considerations and governance of a genomics research biobank, Generation Scotland, are explored within the evolving policy landscape of the past ten years. During this time data sharing and open data access have become increasingly important topics in biomedical research. Decisions around data access are influenced by local arrangements for governance and practices such as linkage to health records, and the global through policies for biobanking and the sharing of data with large-scale biomedical research data resources and consortia...
December 28, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/29281113/complication-rates-and-maintenance-of-correction-after-3-column-osteotomy-in-the-elderly-report-of-55-patients-with-2-year-follow-up
#15
Vincent Challier, Jensen K Henry, Shian Liu, Christopher Ames, Khaled Kebaish, Ibrahim Obeid, Richard Hostin, Munish Gupta, Oheneba Boachie-Adjei, Justin S Smith, Gregory Mundis, Shay Bess, Frank Schwab, Virginie Lafage
BACKGROUND: Three-column osteotomies (3CO) provide substantial correction for adult spinal deformity (ASD), but carry risks of complications and revisions. The risk-benefit balance of 3CO in the elderly remains unclear. OBJECTIVE: To evaluate sagittal alignment and complications after 3CO in a population over 70-yr old. METHODS: Radiographic retrospective review of consecutive patients over 70 yr ("Elderly") undergoing 3CO for ASD. Demographic, operative, and outcomes data were collected...
December 21, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29277900/brain-maps-4-0-structure-of-the-rat-brain-an-open-access-atlas-with-global-nervous-system-nomenclature-ontology-and-flatmaps
#16
Larry W Swanson
The fourth edition (following editions in 1992, 1998, 2004) of Brain maps: structure of the rat brain is presented here as an open access internet resource for the neuroscience community. One new feature is a set of 10 hierarchical nomenclature tables that define and describe all parts of the rat nervous system within the framework of a strictly topographic system devised previously for the human nervous system. These tables constitute a global ontology for knowledge management systems dealing with neural circuitry...
December 26, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29277028/are-we-simplifying-balance-evaluation-in-adolescent-idiopathic-scoliosis
#17
Saba Pasha, Keith Baldwin
BACKGROUND: Clinical evaluation of the postural balance in adolescent idiopathic scoliosis has been measured by sagittal vertical axis and frontal balance. The impact of the scoliotic deformity in three planes on balance has not been fully investigated. METHODS: 47 right thoracic and left lumbar curves adolescent idiopathic scoliosis and 10 non-scoliotic controls were registered prospectively. 13 spinopelvic postural parameters were calculated from the 3-dimantional reconstructions of X-rays...
November 29, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29275932/an-in-vitro-study-to-assess-the-feasibility-validity-and-precision-of-capturing-oncology-facial-defects-with-multimodal-image-fusion
#18
Rachael Y Jablonski, Cecilie A Osnes, Balvinder S Khambay, Brian R Nattress, Andrew J Keeling
AIM: Assess the feasibility, validity and precision of multimodal image fusion to capture oncology facial defects based on plaster casts. METHODS: Ten casts of oncology facial defects were acquired. To create gold standard models, a 3D volumetric scan of each cast was obtained with a cone beam computed tomography (CBCT) scanner (NewTomVG). This was converted into surface data using open-source medical segmentation software and cropped to produce a CBCT mask using an open-source system for editing meshes...
December 21, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29261545/the-effect-of-high-frequency-structured-expert-feedback-on-the-learning-curves-of-basic-interventional-ultrasound-skills-applied-to-regional-anesthesia
#19
Getúlio Rodrigues de Oliveira Filho, Francisco de Assis Caire Mettrau
BACKGROUND: Proficiency in needle-to-ultrasound beam alignment and accurate approach to structures are pivotal for ultrasound-guided regional anesthesia. This study evaluated the effects of high-frequency, structured expert feedback on simulation training of such abilities. METHODS: Forty-two subjects randomly allocated as controls or intervention participated in two 25-trial experiments. Experiment 1 consisted of inserting a needle into a bovine muscular phantom parallel to the ultrasound beam while maintaining full imaging of the needle...
December 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29261541/the-medical-school-admissions-process-and-meeting-the-public-s-health-care-needs-never-the-twain-shall-meet
#20
Jennifer Cleland
Medical schools typically assess how good their selection process is using metrics such as students' assessment performance and the academic success of alumni on later indicators of academic ability and clinical competence, such as Royal College of Physicians or specialty board examinations. To address global issues with the maldistribution of doctors and increasing numbers of new medical school graduates choosing not to work in a clinical context requires different measurements of medical school admissions processes, like those related to graduates' career outcomes (e...
December 19, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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