J Isabelle Choi, Beryl McCormick, Peter Park, Mark Millar, Katherine Walker, Chih Chun Tung, Sheng Huang, Peter Florio, Chin-Cheng Chen, Alicia Lozano, Alexandra L Hanlon, Jana Fox, Amy J Xu, Melissa Zinovoy, Boris Mueller, Richard Bakst, Quincey LaPlant, Lior Z Braunstein, Atif J Khan, Simon N Powell, Oren Cahlon
PURPOSE: Recurrent or new primary breast cancer requiring comprehensive regional nodal irradiation after prior radiation therapy (RT) to the supraclavicular area and upper axilla is challenging due to cumulative brachial plexus (BP) dose tolerance. We assessed BP dose sparing achieved with pencil beam scanning proton therapy (PBS-PT) and photon volumetric modulated arc therapy (VMAT). METHODS AND MATERIALS: In an institutional review board-approved planning study, all patients with ipsilateral recurrent breast cancer treated with PBS-PT re-RT (PBT1) with at least partial BP overlap from prior photon RT were identified...
February 2024: Advances in Radiation Oncology