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Skull base osteomyelitis

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https://www.readbyqxmd.com/read/29887928/skull-base-osteomyelitis-secondary-to-scedosporium-apiospermum-infection
#1
Martin Doss, David Doss
Scedosporium apiospermum is a common environmental mold which is increasingly reported in the literature as a cause of infection, particularly in the immunocompromised patient population. We present a case of malignant otitis externa due to S apiospermum , complicated by spread of infection causing skull base osteomyelitis, internal carotid artery vasculitis and subsequent stroke. Despite the multiple complications encountered, prompt diagnosis and initiation of appropriate antifungal treatment resulted in patient survival...
August 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29866241/voriconazole-induced-severe-periostitis-deformans
#2
Shakir Hussain
Periostitis deformans is an uncommon condition of the skeletal system, mainly manifested as bone pain with or without bony swellings. Voriconazole-induced periostitis is widely reported in the literature, mainly in the organ transplant patients on immunosuppressant therapy. The patient in this case report, was not on any immunosuppressant therapy, but developed widespread periostitis deformans secondary to voriconazole, who was being treated for the base of skull aspergillus osteomyelitis. This report demonstrates the severity of voriconazole adverse effects and the wider impact on patient...
June 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29799068/a-rare-presentation-of-skull-base-osteomyelitis-with-neurovascular-sheath-extension-following-external-otitis-resolved-by-pet-mri
#3
Nicolas Louarn, Quentin Alias, Laurène Aupin, Nicolas Benoist, Marine Desroches, Alain Luciani, Damien Bresson, Jérôme Hodel, Emmanuel Itti
No abstract text is available yet for this article.
May 24, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29744230/skull-base-osteomyelitis-from-otitis-media-presenting-as-the-collet-sicard-syndrome
#4
Wong-Kein Low, Hui-Ling Lhu
Skull base osteomyelitis can involve the jugular foramen and its associated cranial nerves resulting in specific clinical syndromes. The Collet-Sicard syndrome describes the clinical manifestations of palsies involving cranial nerves IX, X, XI, and XII. We present a rare atypical case of skull base osteomyelitis originating from infection of the middle ear and causing the Collet-Sicard syndrome. Caused by Pseudomonas aeruginosa and Klebsiella pneumoniae , this occurred in an elderly diabetic man subsequent to retention of a cotton swab in an ear with chronic suppurative otitis media...
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29594240/skull-base-or-cervical-vertebral-osteomyelitis-following-chemoradiotherapy-for-pharyngeal-carcinoma-a-serious-but-treatable-complication
#5
Nafisha Lalani, Shao Hui Huang, Coleman Rotstein, Eugene Yu, Jonathan Irish, Brian O'Sullivan
Osteomyelitis, infection of the bone and marrow, following high dose (chemo-)radiotherapy for head and neck cancer is uncommon and rarely seen in the cervical spine or temporal bone. Due to its proximity to critical structures, osteomyelitis in the latter regions could carry potentially important consequences. Furthermore, involvement near the skull base (e.g. temporal bone and high cervical vertebrae) presents unique challenges in diagnosis (especially in the differentiation from disease recurrence) and treatment, making early detection and timely intervention critical...
January 2018: Clinical and translational radiation oncology
https://www.readbyqxmd.com/read/29590490/fatal-invasive-otitis-with-skull-base-osteomyelitis-caused-by-saksenaea-vasiformis
#6
Elise Marechal, Fatima Barry, Fréderic Dalle, Louise Basmaciyan, Stéphane Valot, Marc Sautour, Christian Duvillard, Pascal Chavanet, Lionel Piroth, Mathieu Blot
No abstract text is available yet for this article.
March 24, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29552249/craniofacial-actinomyces-osteomyelitis-evolving-from-sinusitis
#7
Joseph Y Shen, Neal D Futran, Maya G Sardesai
Craniofacial Actinomyces osteomyelitis progression is rare, as patients are soon treated. A 56-year-old male smoker presented with sinusitis and was managed medically. This patient failed to follow up and presented 1 year later with erosive bony disease. He was managed medically and surgically; however, his disease evolved to include his midface, skull base, and cranium. He underwent staged debridement and free tissue reconstruction. His disease is controlled but not cured. The literature includes case reports and small series describing limited disease treated successfully with surgical and medical management...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29416952/advanced-imaging-techniques-in-skull-base-osteomyelitis-due-to-malignant-otitis-externa
#8
REVIEW
A M J L van Kroonenburgh, W L van der Meer, R J P Bothof, M van Tilburg, J van Tongeren, A A Postma
Purpose of Review: To give an up-to-date overview of the strengths and weaknesses of current imaging modalities in diagnosis and follow-up of skull base osteomyelitis (SBO). Recent Findings: CT and MRI are both used for anatomical imaging, and nuclear techniques aid in functional process imaging. Hybrid techniques PET-CT and PET-MRI are the newest modalities which combine imaging strengths. Summary: No single modality is able to address the scope of SBO...
2018: Current Radiology Reports
https://www.readbyqxmd.com/read/29098132/mycotic-pseudoaneurysm-associated-with-skull-base-osteomyelitis-treated-with-endovascular-embolization
#9
Ali S Haider, Brandon I Esianor, Mrigank S Shail, Margaret I Engelhardt, Aida Kafai Golahmadi, Ramiz Khan, Umair Khan, Steven Vayalumkal, Richa Thakur, Kennith F Layton
Pseudoaneurysms occur due to malformations in arterial wall uniformity, leading to blood collection between the outer arterial layers and resultant outpouching of the vessel. Unlike true aneurysms, pseudoaneurysms do not involve all layers of the blood vessel. Mycotic pseudoaneurysms can occur after associated vessel adventitia infection, leading to transmural dissection. Here we present a case of a 78-year-old man with a history of chronic otitis externa and osteomyelitis who presented with increasing right ear pain with bloody discharge and associated headache...
August 28, 2017: Curēus
https://www.readbyqxmd.com/read/29097032/-the-infections-of-the-ear
#10
Catherine Nowak, Lei Tanaka, Serge Bobin, Jérôme Nevoux
In front of external otitis in spite of a well-conducted treatment, especially in immunodeficient patient, it is always necessary to look for an osteomyelitis of the skull base that requires an urgent parenteral antibiotic treatment of several weeks. Acute otitis media (AOM) is the most common bacterial infection of the child. In children under 2 years with purulent AOM, antibiotic therapy with amoxicilline is systematic for a period of 8-10 days. After 2 years of age and with mild symptoms of AOM, symptomatic treatment may be justified as first-line treatment...
November 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28994125/propionibacterium-acnes-as-an-emerging-pathogen-in-skull-base-osteomyelitis-a-case-series
#11
Heather K Schopper, Jonathan L Hatch, Ted A Meyer
Skull base osteomyelitis (SBO) is recognized as a potentially life-threatening infection that has been classically attributed to Pseudomonas aeruginosa. However, growing data shows that the bacteriology of SBO is changing. Traditionally thought of as commensal bacterium, P. acnes has been implicated as a serious pathogen in other specialties. Building on a previous case report from our institution, we have identified three patients with SBO who are culture-positive for Propionibacterium acnes as a single isolate...
February 2018: Laryngoscope
https://www.readbyqxmd.com/read/28724596/severe-destructive-nasopharyngeal-granulomatosis-with-polyangiitis-with-superimposed-skull-base-pseudomonas-aeruginosa-osteomyelitis
#12
Mitchell S von Itzstein, Jithma P Abeykoon, Daniel D Summerfield, Jennifer A Whitaker
Skull base osteomyelitis in the setting of granulomatosis with polyangiitis (GPA) is rare and entails significant diagnostic challenges. We present a case of a 65-year-old Caucasian man with a history of rheumatoid arthritis, off immunosuppression for 18 months, who presented with 2 years of chronic headaches, severe fatigue, saddle nose deformity and 20-kilogram unintentional weight loss. Maxillofacial CT revealed an extensive destructive sinonasal and erosive skull base process. Laboratory evaluation showed equivocal elevation of antiproteinase 3 antibodies with negative antineutrophil cytoplasmic antibody panel...
July 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28593115/clival-osteomyelitis-presenting-as-a-skull-base-mass
#13
Matthew Michalowicz, Murugappan Ramanathan
Central skull base osteomyelitis is a rare, but potentially life-threatening disease entity often lacking otologic symptoms or external auditory canal pathology. We present a case of a man in his 70s who had developed cranial nerve deficits with radiographic evidence that was consistent with a tumor due to this uncommon entity. The radiologic findings and our experience are discussed to increase awareness in the otolaryngology community.
April 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28487802/clinical-challenges-in-the-diagnosis-and-treatment-of-temporal-bone-osteomyelitis
#14
Liubov Kornilenko, Saulius Rocka, Svajunas Balseris, Irina Arechvo
Temporal bone osteomyelitis is a serious life-threatening condition-a quick and proper diagnosis is needed to start treatment and reduce morbidity and mortality. Changing trends of the disease make a differential diagnosis difficult. To emphasize the importance of a clinical suspicion of this dangerous condition, our experience with three difficult cases is presented. The diagnosis was based on clinical symptoms, otoscopic findings, and findings on computed tomography or magnetic resonance imaging. Neoplasm and granulomatous inflammation were excluded by multiple biopsies...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28483146/skull-base-osteomyelitis-secondary-to-malignant-otitis-externa-mimicking-advanced-nasopharyngeal-cancer-mr-imaging-features-at-initial-presentation
#15
J P N Goh, A Karandikar, S C Loke, T Y Tan
PURPOSE: Skull base osteomyelitis (SBOM) is an inflammatory process which often arises from malignant otitis externa (MOE); the diffuse skull base and adjacent soft tissue involvement may be mistaken at initial imaging for advanced nasopharyngeal carcinoma (NPC), especially if there is no prior knowledge of MOE, direct spread from the sphenoid sinus or in atypical presentations of MOE. This study aims to evaluate imaging features on MR that may differentiate SBOM from NPC. MATERIALS AND METHODS: The MR examinations of 26 patients diagnosed with SBOM between January 1996 and January 2013 were retrospectively reviewed...
July 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28301961/current-management-of-necrotising-otitis-externa-in-the-uk-survey-of-221-uk-otolaryngologists
#16
Gaurav Chawdhary, Miran Pankhania, Susan Douglas, Ian Bottrill
INTRODUCTION: Necrotising otitis externa (NOE) is a rare infection causing skull base osteomyelitis. The evidence regarding NOE consists mostly of case series. Hence, there is a limited evidence base to guide decision-making. This survey aims to report the experience of 221 otolaryngologists in this condition. MATERIALS AND METHODS: Internet survey administered to the membership of the British Association of Otorhinolaryngology - Head and Neck Surgery (ENT UK). RESULTS: Respondents' detailed replies on diagnosis, treatment and follow up are presented...
August 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28219414/severe-skull-base-osteomyelitis-caused-by-pseudomonas-aeruginosa-with-successful-outcome-after-prolonged-outpatient-therapy-with-continuous-infusion-of-ceftazidime-and-oral-ciprofloxacin-a-case-report
#17
Cristina Conde-Díaz, Jara Llenas-García, Mónica Parra Grande, Gertrudis Terol Esclapez, Mar Masiá, Félix Gutiérrez
BACKGROUND: Skull base osteomyelitis is an uncommon disease that usually complicates a malignant external otitis with temporal bone involvement. It affects predominantly diabetic and immunocompromised males and has a high mortality rate. Pseudomonas aeruginosa is the most common causative organism. Currently, there is no consensus about the best therapeutic option. Here we describe a case of severe skull base osteomyelitis caused by Pseudomonas aeruginosa with progressive palsy of cranial nerves that was successfully managed with prolonged outpatient continuous infusion of ceftazidime plus oral ciprofloxacin...
February 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27861948/propionibacterium-skull-base-osteomyelitis-complicated-by-internal-carotid-artery-pseudoaneurysm
#18
Kathryn L Kreicher, Jonathan L Hatch, Shivangi Lohia, Ted A Meyer
The microbiology of skull base osteomyelitis (SBO) is evolving. We present here the first case of SBO caused by Propionibacterium acnes leading to the development of a pseudoaneurysm of the internal carotid artery. Otolaryngologists should recognize this pathogen as a potential cause of invasive temporal bone infection to optimize prompt diagnosis and treatment. Laryngoscope, 127:2337-2339, 2017.
October 2017: Laryngoscope
https://www.readbyqxmd.com/read/27730788/skull-base-osteomyelitis-caused-by-an-elegant-fungus
#19
Sharafine Stephen, Beula Subashini, Regi Thomas, Ajay Philip, Rajan Sundaresan
Malignant otitIs externa (skull base osteomyelitis) is predominantly caused by bacteria while fungal etiology is rare. We report a middle aged diabetic gentleman who succumbed to invasive skull base infection due to Apophysomyces elegans a fungus belonging to Zygomycetes which causes only skin and soft tissue infections. Mortality and invasive infections due to this genus is rarely reported, especially in the ear.
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27701039/central-skull-base-osteomyelitis-involving-cavernous-sinus-and-meninges-of-the-skull-base-successful-treatment-with-antibiotic-and-antifungal-combination-therapy
#20
Tatsuya Ueno, Haruo Nishijima, Rie Haga, Masahiko Tomiyama
No abstract text is available yet for this article.
November 2016: Clinical Neurology and Neurosurgery
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