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https://www.readbyqxmd.com/read/28092930/prevalence-of-latent-tuberculosis-among-laboratory-healthcare-workers-in-iran-a-cross-sectional-study
#1
Mahshid Nasehi, Abdolrazagh Hashemi-Shahraki, Amin Doosti-Irani, Saeed Sharafi, Ehsan Mostafavi
Objectives: The risk of transmission of Mycobacterium tuberculosis from patients to health-care workers (HCWs) is a neglected problem in many countries including Iran. The aim of this study was to estimate the prevalence of latent tuberculosis infection (LTBI), and related risk factors among TB laboratory staff in Iran. Methods: All TB laboratory staff (689 individual) who were working in TB laboratories of 50 Iranian Universities of Medical Sciences and a random sample consisted of 317 participants from low risk HCWs, were included in this cross sectional study...
December 30, 2016: Epidemiology and Health
https://www.readbyqxmd.com/read/28077402/elemental-metabolomics
#2
Ping Zhang, Constantinos A Georgiou, Vladimir Brusic
Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples. In living organisms, elements interact and compete with each other for absorption and molecular interactions. They also interact with proteins and nucleotide sequences. These interactions modulate enzymatic activities and are critical for many molecular and cellular functions...
January 10, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28076528/the-brief-life-of-norplant%C3%A2-in-brazil-controversies-and-reassemblages-between-science-society-and-state
#3
Ana Cristina de Lima Pimentel, Cláudia Bonan Jannotti, Paula Gaudenzi, Luiz Antonio da Silva Teixeira
Norplant® is the brand name of the world's first registered subdermal hormonal contraceptive implant, developed by the laboratories of the Population Council, an international organisation working in the area of fertility and population growth. The article revisits the trajectory of this contraceptive in Brazil from its arrival through clinical trials to its eventual ban in 1986 by the Brazilian regulatory agency responsible for approving medications at the time. Its circulation generated controversies related to research practices, side effects and political uses of the drug as a birth control method...
January 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28070529/low-prevalence-of-aeromonas-hydrophilain-infectious-diarrhea-samples-of-pediatric-patients-in-arak-iran
#4
Abbasi Elnaz, Khansari-Nejad Behzad, Abtahi Hamid, Akbari Majid, Ghaznavi-Rad Ehsanollah
BACKGROUND: Aeromonashydrophila (A. hydrophila) is an aquatic bacterium that can cause a spectrum of infectious diseases, including both gastrointestinal and extraintestinal infections. Due to the high rate of diarrheal infections in pediatric patients in central Iran, this study was designed to determine the frequency of A. hydrophila in diarrhea samples from children in this region. METHODS: In this descriptive cross-sectional study, diarrheal stool specimens were collected from 200 children admitted between February and October of 2015 to educational and medical centers affiliated with the Arak University of Medical Sciences...
October 2016: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28050231/treatment-of-patients-with-refractory-metastatic-cancer-according-to-molecular-profiling-on-tumor-tissue-in-the-clinical-routine-an-interim-analysis-of-the-onco-t-profile-project
#5
Andreas Seeber, Guenther Gastl, Christian Ensinger, Gilbert Spizzo, Wolfgang Willenbacher, Florian Kocher, Christoph Leitner, Ella Willenbacher, Arno Amann, Normann Steiner, Wolfgang Eisterer, Andreas Voss, Kenneth Russell, Heinz Zwierzina
INTRODUCTION: Patients with refractory metastatic cancer have been shown to benefit from molecular profiling of tumor tissue. The ONCO-T-PROFILE project was launched in March 2014 at the Innsbruck Medical University. Within 2 years our project aims to recruit 110 patients with stage IV cancer refractory to standard therapy. Our data presented here are based on an interim-analysis. METHODS: Tumor tissue specimens were submitted for molecular profiling to the certified laboratory (Caris Life Science, USA)...
September 2016: Genes & Cancer
https://www.readbyqxmd.com/read/28049892/maintenance-of-clinical-expertise-and-clinical-research-by-the-clinical-professors-at-gifu-pharmaceutical-university
#6
Tomoya Tachi, Yoshihiro Noguchi, Hitomi Teramachi
 The clinical professors at Gifu Pharmaceutical University (GPU) provide pharmaceutical services at GPU Pharmacy, Gifu University Hospital, and Gifu Municipal Hospital to keep their clinical skills up-to-date; they also perform clinical research in collaboration with many clinical institutes. The Laboratory of Clinical Pharmacy is part of the Department of Pharmacy Practice and Science, to which the clinical professors belong, and is composed of three clinical professors (a professor, an associate professor, and an assistant professor)...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28048283/we-h-204-03-part-2-history-and-archives-resources-at-aip-for-aapm-and-its-members
#7
M Mueller
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047523/we-h-204-00-history-committee-symposium
#8
Michael Gossman
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046866/we-h-204-01-william-d-coolidge-inventor-of-the-modern-x-ray-tube
#9
D Allard
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046206/we-h-204-02-part-1-history-and-archives-resources-at-aip-for-aapm-and-its-members
#10
G Good
: "William D. Coolidge, Inventor of the Modern X-ray Tube" David J. Allard, M.S., CHP - Director, PA DEP Bureau of Radiation Protection William David Coolidge 1873-1975 was a research scientist and inventor of the modern X-ray tube. Besides Roentgen, with his 1895 discovery and subsequent studies of X-rays, perhaps no other individual contributed more to the advancement of X-ray technology than did Coolidge. He was born in Hudson, MA and received his Bachelor of Science degree from MIT in 1896...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28034577/10-lessons-learned-by-a-misguided-physician
#11
REVIEW
Barry E Levin
It was a great and humbling honor to receive the 2016 Distinguished Career Award from my SSIB colleagues. This paper summarizes the major points of my DCA talk at the 2016 annual meeting. It is a reflection on my 50year medical and research career and 10 lessons I have learned over those years which might be of help to young investigators near the beginning of their own research careers. These lessons include: the value of being receptive to the opportunities provided you; how clinician-scientists can serve as critical role models for young investigators like me and a history of how my career developed as a result of their influence; the importance of carefully examining your own data, particularly when it doesn't agree with your preconceived ideas; the critical role that students, postdocs and PhD (and even veterinarian) colleagues can play in developing one's career; the likelihood that your career path will have many interesting twists and turns determined by changes in your own scientific interests and how rewarding various areas of research focus are to you; the importance of building a close-knit laboratory staff family; the fact that science and romance can mix...
December 26, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/28010905/an-investigation-of-antimicrobial-usage-patterns-by-small-animal-veterinarians-in-south-africa
#12
John K Chipangura, Hayley Eagar, Marcia Kgoete, Darrell Abernethy, Vinny Naidoo
AIM: At present very little information is available on antimicrobial use patterns in small animal veterinary practice in South Africa. The aim of this study was firstly to provide some indication of antimicrobial use patterns, and secondly to ascertain if the country's small animal veterinarians make use of prudent use guidelines to optimise their antimicrobial use in order to minimise the development of antimicrobial resistance. METHODOLOGY: In order to understand use patterns, a questionnaire was circulated to registered South African veterinarians, whose responses were evaluated by descriptive statistics...
January 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/27968913/pharmacological-mechanisms-of-euphorbia-pekinensis-and-glycyrrhiza-acting-on-hepatocellular-carcinoma-ascites-a-preclinical-study
#13
Xia Mao, Chen Yan, Yuting Li, Ya Lin, Qiuyan Guo, Yanqiong Zhang, Na Lin
BACKGROUND: According to Chinese medicinal literature, Euphorbia Pekinensis and Glycyrrhiza should not be used together because of their antagonistic actions. However, increasing experimental and clinical evidence show that they exhibit synergistic or antagonistic actions when used together in different combinations. The aim of this study was to clarify the herbaceous compatibility of Euphorbia Pekinensis and Glycyrrhiza acting on hepatocellular carcinoma (HCC) ascites, which has not been fully elucidated...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968882/effects-of-patient-load-and-travel-distance-on-hiv-transmission-in-a-cohort-of-serodiscordant-couples-in-rural-china-a-longitudinal-analysis
#14
M Kumi Smith, William C Miller, Huixin Liu, Chuanyi Ning, Wensheng He, Myron S Cohen, Ning Wang
BACKGROUND: Sustained viral suppression through antiretroviral therapy (ART) reduces the risk of sexual HIV transmission. However, it can require routine access to reliable and effective medical care, which can be difficult to obtain in resource-constrained areas. We investigated the effects of patient load and travel distance to an HIV care clinic on transmission risk in HIV serodiscordant couples in the Henan Province, China. METHODS: The study cohort arises from a population of HIV-infected individuals in central rural China where regional blood selling scandals in the 1990s led to mass HIV transmission of up to 30 000 people though unsanitary blood collection practices...
October 2016: Lancet
https://www.readbyqxmd.com/read/27968827/operational-challenges-to-the-1-3-7-surveillance-strategy-for-malaria-elimination-in-china-a-qualitative-study
#15
Guang-Yu Lu, Yao-Bao Liu, Claudia Beiersmann, Yu Feng, Jun Cao, Olaf Müller
BACKGROUND: China aims to eliminate malaria by 2020. In 2012, China launched its 1-3-7 malaria surveillance strategy, which refers to case reporting within one day, case investigation within three days, and focus investigation and public health actions within seven days. The aim of this study was to identify operational challenges to the 1-3-7 surveillance strategy. METHODS: This qualitative study was conducted in northwestern (Gansu Province) and southeastern (Jiangsu Province) China...
October 2016: Lancet
https://www.readbyqxmd.com/read/27967227/sodium-and-water-imbalance-after-sellar-suprasellar-and-parasellar-surgery
#16
Zareen Kiran, Aisha Sheikh, Sehrish Nizar Ali Momin, Isra Majeed, Safia Awan, Owais Rashid, Najmul Islam
OBJECTIVES: To report the frequency of sodium and water disturbances (SWD) in patients undergoing sellar, suprasellar and parasellar surgery (SSPS). METHODS: We conducted a cross-sectional retrospective study on 115 patients in the Aga Khan University Hospital after ethical approval. Patients were 16 years old or older undergoing pituitary or sellar surgeries. We collected data on basic sociodemographic characteristics and clinical indication for surgery. We noted laboratory values for serum electrolytes, plasma and urine osmolality, urine sodium and 24-hour fluid balance from immediate postoperative day till discharge and follow up...
December 14, 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27960229/automated-telephone-communication-systems-for-preventive-healthcare-and-management-of-long-term-conditions
#17
REVIEW
Pawel Posadzki, Nikolaos Mastellos, Rebecca Ryan, Laura H Gunn, Lambert M Felix, Yannis Pappas, Marie-Pierre Gagnon, Steven A Julious, Liming Xiang, Brian Oldenburg, Josip Car
BACKGROUND: Automated telephone communication systems (ATCS) can deliver voice messages and collect health-related information from patients using either their telephone's touch-tone keypad or voice recognition software. ATCS can supplement or replace telephone contact between health professionals and patients. There are four different types of ATCS: unidirectional (one-way, non-interactive voice communication), interactive voice response (IVR) systems, ATCS with additional functions such as access to an expert to request advice (ATCS Plus) and multimodal ATCS, where the calls are delivered as part of a multicomponent intervention...
14, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27956910/mutation-analysis-of-three-exons-of-myosin-binding-protein-c3-in-patients-with-hypertrophic-cardiomyopathy
#18
Maryam Beigom Mobasheri, Mohammad Hossein Modarressi, Cirus Darabian, Ali Akbar Zeinalou
Background: Hypertrophic cardiomyopathy is a genetic disorder with a prevalence rate of 0.2% in the general population. It comes from mutations in sarcomeric proteins. Cardiac myosin-binding protein C3 is one of the critical genes in hypertrophic cardiomyopathy (HCM) and sudden cardiac death, accounting for about 20% of HCM-causing mutations. Genetic testing is recommended in patients with HCM. The aim of the current study was to find possible disease-causing mutations in 3 exons of the gene myosin-binding protein C (MYBPC3) in patients with HCM...
July 6, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/27933614/antiviral-agents-for-infectious-mononucleosis-glandular-fever
#19
REVIEW
Muireann De Paor, Kirsty O'Brien, Tom Fahey, Susan M Smith
BACKGROUND: Infectious mononucleosis (IM) is a clinical syndrome, usually caused by the Epstein Barr virus (EPV), characterised by lymphadenopathy, fever and sore throat. Most cases of symptomatic IM occur in older teenagers or young adults. Usually IM is a benign self-limiting illness and requires only symptomatic treatment. However, occasionally the disease course can be complicated or prolonged and lead to decreased productivity in terms of school or work. Antiviral medications have been used to treat IM, but the use of antivirals for IM is controversial...
8, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27927923/biofeature-lynne-s-garcia-m-s-f-aam
#20
Betty A Forbes
Comments provided by Mike Saubolle, Medical Director, Infectious Diseases Division, Laboratory Sciences of Arizona and Clinical Associate Professor at the University of Arizona College of Medicine in Tuscon set the stage for Lynne S Garcia's, M.S., F(AAM) biofeature and capture the spirit of Lynne ….
December 7, 2016: Journal of Clinical Microbiology
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