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https://www.readbyqxmd.com/read/28441301/regenerative-medicine-and-stem-cells-in-dermatology
#1
Eduardo K Moioli, Diana Bolotin, Murad Alam
BACKGROUND: Clinically relevant regenerative medicine is still in its early stages of development. Difficulties in regenerating large-scale and complex structures, the lack of safety data, and the paucity of clinical trials have slowed the process of technological advance. OBJECTIVE: To familiarize the clinician with techniques available in the laboratory and experimental approaches being tested clinically. In addition, a layout is discussed for how dermatologists can lead the way in bringing regenerative medicine to clinical reality...
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28419268/the-american-society-for-clinical-pathology-s-2015-wage-survey-of-medical-laboratories-in-the-united-states
#2
Edna Garcia, Patrick B Fisher
Objectives: To inform the pathology and laboratory field of the most recent national wage data from the American Society for Clinical Pathology (ASCP). Historically, the results of this biennial survey have served as a basis for additional research on laboratory recruitment, retention, education, marketing, certification, and advocacy. Methods: The 2015 wage survey was conducted through collaboration between the ASCP's Institute of Science, Technology, and Policy in Washington, DC, and the ASCP Board of Certification in Chicago, Illinois...
April 15, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28395055/implementation-and-evaluation-of-a-blended-learning-course-on-tuberculosis-for-front-line-health-care-professionals
#3
Tsegahun Manyazewal, Francesco Marinucci, Getachew Belay, Abraham Tesfaye, Amha Kebede, Yewondwossen Tadesse, Susan Lehman, Zelalem Temesgen
Objectives: To implement and evaluate the effectiveness of a 10-module blended learning course on tuberculosis diagnosis for Ethiopian health care professionals. Methods: This implementation science research was conducted within the routine in-service training for health care professionals in Ethiopia. A combined web-based and face-to-face acid-fast bacilli microscopy course was designed and its applicability studied after 6 weeks of enrollment of 108 medical laboratory professionals...
March 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28369755/strengthening-medical-education-in-haematology-and-blood-transfusion-postgraduate-programmes-in-tanzania
#4
REVIEW
Julie Makani, Magdalena Lyimo, Pius Magesa, David J Roberts
Haematology and blood transfusion, as a clinical and laboratory discipline, has a far-reaching impact on healthcare both through direct patient care as well as provision of laboratory and transfusion services. Improvement of haematology and blood transfusion may therefore be significant in achieving advances in health in Africa. In 2005, Tanzania had one of the lowest distributions of doctors in the world, estimated at 2·3 doctors per 100 000 of population, with only one haematologist, a medical doctor with postgraduate medical education in haematology and blood transfusion...
April 3, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28365617/the-francis-crick-institute
#5
Keith Peters, Jim Smith
The Francis Crick Institute Laboratory, opened in 2016, is supported by the Medical Research Council, Cancer Research UK, the Wellcome Trust, and University College London, King's College London and Imperial College London. The emphasis on research training and early independence of gifted scientists in a multidisciplinary environment provides unique opportunities for UK medical science, including clinical and translational research.
April 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28365182/hopes-and-disappointments-with-antiarrhythmic-drugs
#6
A John Camm
Ventricular arrhythmias such as sustained ventricular tachycardia and ventricular fibrillation account for two thirds of sudden cardiac deaths. Most ventricular tachyarrhythmias have well understood mechanisms such that it is theoretically possible to conceive of an antiarrhythmic drug-based intervention that would prevent arrhythmias that cause sudden cardiac death. Pharmaceutical agents which interfere with ion channel activity are known as antiarrhythmic drugs. Acute experiments showing antiarrhythmic effects in the basic science laboratory have often not translated into clinical effectiveness...
March 16, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28343097/strait-razor-v2s-advancing-sequence-based-str-allele-reporting-and-beyond-to-other-marker-systems
#7
Jonathan L King, Frank R Wendt, Jie Sun, Bruce Budowle
STRait Razor has provided the forensic community a free-to-use, open-source tool for short tandem repeat (STR) analysis of massively parallel sequencing (MPS) data. STRait Razor v2s (SRv2s) allows users to capture physically phased haplotypes within the full amplicon of both commercial (ForenSeq) and "early access" panels (PowerSeq, Mixture ID). STRait Razor v2s may be run in batch mode to facilitate population-level analysis and is supported by all Unix distributions (including MAC OS). Data are reported in tables in string (haplotype), length-based (e...
March 12, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28339797/the-american-society-for-clinical-pathology-s-2015-wage-survey-of-medical-laboratories-in-the-united-states
#8
Edna Garcia, Patrick B Fisher
Objectives: To inform the pathology and laboratory field of the most recent national wage data from the American Society for Clinical Pathology (ASCP). Historically, the results of this biennial survey have served as a basis for additional research on laboratory recruitment, retention, education, marketing, certification, and advocacy. Methods: The 2015 wage survey was conducted through collaboration between the ASCP's Institute of Science, Technology, & Policy in Washington, DC, and the ASCP Board of Certification in Chicago, Illinois...
April 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28339374/basics-of-compounding-clinical-pharmaceutics-part-1
#9
Loyd V Allen
Pharmaceutics is relevant far beyond the pharmaceutical industry, compounding, and the laboratory. Pharmaceutics can be used to solve many clinical problems in medication therapy. A pharmacists' knowledge of the physicochemical aspects of drugs and drug products should help the patient, physician, and healthcare professionals resolve issues in the increasingly complex world of modern medicine. Pharmacy is unique as it contains a knowledge base significantly different from that of physicians, nurses, and other health-related practitioners...
September 2016: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28332640/leptospirosis-in-domestic-animals-in-france-serological-results-from-1988-to-2007
#10
G André-Fontaine
Leptospirosis is a common infection in domestic animals. The microscopic agglutination test (MAT) is used for serological diagnosis. From 1988 to 2007, the Leptospira Medical and Molecular Bacteriology Laboratory at the Nantes National College of Veterinary Medicine, Food Science and Engineering used the MAT to test serum samples from more than 40,000 cattle, 40,000 pigs, 20,000 horses and 9,500 dogs. Five Leptospira serogroups were prominent, with specific variations within the four animal species: Icterohaemorrhagiae, Australis, Sejroë, Grippotyphosa and Autumnalis...
December 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28326513/manual-vs-computer-assisted-sperm-analysis-can-casa-replace-manual-assessment-of-human-semen-in-clinical-practice
#11
Joanna Talarczyk-Desole, Anna Berger, Grażyna Taszarek-Hauke, Jan Hauke, Leszek Pawelczyk, Piotr Jedrzejczak
OBJECTIVES: The aim of the study was to check the quality of computer-assisted sperm analysis (CASA) system in comparison to the reference manual method as well as standardization of the computer-assisted semen assessment. MATERIAL AND METHODS: The study was conducted between January and June 2015 at the Andrology Laboratory of the Division of Infertility and Reproductive Endocrinology, Poznań University of Medical Sciences, Poland. The study group consisted of 230 men who gave sperm samples for the first time in our center as part of an infertility investigation...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28326064/contribution-of-ultra-deep-sequencing-in-the-clinical-diagnosis-of-a-new-fungal-pathogen-species-basidiobolus-meristosporus
#12
Emilie Sitterlé, Christophe Rodriguez, Roman Mounier, Julien Calderaro, Françoise Foulet, Michel Develoux, Jean-Michel Pawlotsky, Françoise Botterel
Some cases of fungal infection remained undiagnosed, especially when the pathogens are uncommon, require specific conditions for in vitro growth, or when several microbial species are present in the specimen. Ultra-Deep Sequencing (UDS) could be considered as a precise tool in the identification of involved pathogens in order to upgrade patient treatment. In this study, we report the implementation of UDS technology in medical laboratory during the follow-up of an atypical fungal infection case. Thanks to UDS technology, we document the first case of gastro-intestinal basidiobolomycosis (GIB) due to Basidiobolus meristosporus...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28280722/tissue-engineered-solutions-in-plastic-and-reconstructive-surgery-principles-and-practice
#13
REVIEW
Sarah Al-Himdani, Zita M Jessop, Ayesha Al-Sabah, Emman Combellack, Amel Ibrahim, Shareen H Doak, Andrew M Hart, Charles W Archer, Catherine A Thornton, Iain S Whitaker
Recent advances in microsurgery, imaging, and transplantation have led to significant refinements in autologous reconstructive options; however, the morbidity of donor sites remains. This would be eliminated by successful clinical translation of tissue-engineered solutions into surgical practice. Plastic surgeons are uniquely placed to be intrinsically involved in the research and development of laboratory engineered tissues and their subsequent use. In this article, we present an overview of the field of tissue engineering, with the practicing plastic surgeon in mind...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28274984/development-of-a-postgraduate-year-2-pharmacy-residency-in-clinical-pharmacogenetics
#14
Cyrine E Haidar, James M Hoffman, Roseann S Gammal, Mary V Relling, Kristine R Crews
PURPOSE: The structure and development of an innovative, ASHP-accredited postgraduate year 2 (PGY2) clinical pharmacogenetics residency program are described. SUMMARY: A 12-month PGY2 clinical pharmacogenetics residency was created at St. Jude Children's Research Hospital in accordance with the ASHP standards for advanced practice residencies. The purpose of this 12-month residency program is to prepare pharmacy residents to implement pharmacogenetics in clinical practice...
March 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28266954/diagnostic-value-of-procalcitonin-on-early-postoperative-infection-after-pediatric-cardiac-surgery
#15
Xia Li, Xu Wang, Shoujun Li, Jun Yan, Dan Li
OBJECTIVES: Assess the diagnostic value of serial monitoring of procalcitonin levels on early postoperative infection after pediatric cardiac surgery with cardiopulmonary bypass. DESIGN: Prospective, observational study. SETTING: A pediatric cardiac surgical ICU (PICU) and pediatric cardiac surgery department at Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College. PATIENTS: Patients were 3 years old and below, underwent cardiac surgery involving cardiopulmonary bypass, the Aristotle Comprehensive Complexity score was 8 or higher and free from active preoperative infection or inflammatory disease...
March 6, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28261791/drug-recognition-evaluation-and-chemical-confirmation-of-a-25c-nbome-impaired-driver
#16
James W Rajotte, Jean-Paul F P Palmentier, Helena Rachelle Wallage
This case report details an individual arrested for drug-impaired driving after leaving the scene of multiple motor vehicle collisions and evading police. The driver was examined by a drug recognition expert and failed the drug recognition evaluation. The driver admitted to using cocaine, marijuana, an antidepressant medication and "N-bomb," a novel psychoactive substance that possesses hallucinogenic properties. Toxicological analyses at the Centre of Forensic Sciences' Toronto laboratory revealed only the substance 2-[4-chloro-2,5-dimethoxyphenyl]-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in the accused's urine...
March 6, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28261553/discernment-scheme-for-paraquat-poisoning-a-five-year-experience-in-shiraz-iran
#17
Saeed Kavousi-Gharbi, Reza Jalli, Akbar Rasekhi-Kazerouni, Zahra Habibagahi, Sayed Mahdi Marashi
AIM: To evaluate various schemes for paraquat poisoning and different variables that influence the outcome of acute paraquat poisoning. METHODS: In a cross-sectional study, the information about all cases of acute paraquat poisoning who were admitted to teaching hospitals affiliated to Shiraz University of Medical Sciences, in a five year period (September 2010 to September 2015) were evaluated. The variables included: Demographic data, medical assessment, therapeutic options, laboratory findings, and the outcomes...
February 20, 2017: World Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28260748/effect-of-obesity-on-fasting-blood-sugar
#18
R Akter, A Nessa, M F Husain, F Wahed, N Khatun, M Yesmin, S Nasreen, T Tajkia
Obesity is a disorder of body weight regulatory systems characterized by an accumulation of excess body fat. World Heath Organization recommended that 66% of deaths now occur in developing countries and recognizes obesity as a leading risk factor. Obesity is associated with chronic, low grade, systemic inflammation. The inflammatory state plays a causal role in the development of insulin resistance, type 2 diabetes and the metabolic syndrome. This study will design to evaluate the relation between obesity with fasting blood sugar (FBS)...
January 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28252618/-the-progressive-models-of-educational-activities-as-a-basis-for-the-training-of-forensic-medical-experts-of-the-new-generation
#19
S A Smirnova, O A Yastrebov
The authors interpret forensic expertology as a synthetic science and propose the models for the training of professionals in the field of forensic medical expertise. They provide a rationale for the realization of such systematic training in the framework of the model of the three-level system based at the educational institutions of higher professional education. Characteristic features of the existing standards of professional training in the sphere of forensic medical expertise are considered with special reference to the organization of education of future forensic medical experts based at the many-level programs adopted in the Russian University of People's Friendship...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28250087/cell-scientist-to-watch-marvin-tanenbaum
#20
(no author information available yet)
Marvin Tanenbaum performed his undergraduate studies in Biomedical Sciences at the University of Amsterdam in The Netherlands. He obtained his PhD from Utrecht University in 2010 cum laude, having worked with René Medema on microtubule motor proteins. He won the Netherlands Association for Medical Education (NVMO) Oncology and Utrecht University Thesis awards, and moved to San Francisco with an EMBO long-term fellowship for his postdoctoral position in Ron Vale's laboratory at University of California, San Francisco (UCSF)...
March 1, 2017: Journal of Cell Science
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