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https://www.readbyqxmd.com/read/29776970/the-e3-ubiquitin-ligase-mib-1-is-necessary-to-form-the-nuclear-halo-in-caenorhabditis-elegans-sperm
#1
Leslie A Herrera, Daniel A Starr
Unlike the classical nuclear envelope with two membranes found in other eukaryotic cells, most nematode sperm nuclei are not encapsulated by membranes. Instead, they are surrounded by a nuclear halo of unknown composition. How the halo is formed and regulated is unknown. We used forward genetics to identify molecular lesions behind three classical fer (fertilization defective) mutations that disrupt the ultrastructure of the Caenorhabditis elegans sperm nuclear halo. We found fer-2 and fer-4 alleles to be nonsense mutations in mib-1...
May 18, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29770763/a-radiomics-nomogram-for-preoperative-prediction-of-microvascular-invasion-risk-in-hepatitis-b-virus-related-hepatocellular-carcinoma
#2
Jie Peng, Jing Zhang, Qifan Zhang, Yikai Xu, Jie Zhou, Li Liu
PURPOSE: We aimed to develop and validate a radiomics nomogram for preoperative prediction of microvascular invasion (MVI) in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). METHODS: A total of 304 eligible patients with HCC were randomly divided into training (n=184) and independent validation (n=120) cohorts. Portal venous and arterial phase computed tomography data of the HCCs were collected to extract radiomic features. Using the least absolute shrinkage and selection operator algorithm, the training set was processed to reduce data dimensions, feature selection, and construction of a radiomics signature...
May 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29766703/meyerson-s-phenomenon-in-melanoma-when-a-halo-dermatitis-hides-a-malignancy
#3
Vincenzo Piccolo, Teresa Russo, Michele Del Vecchio, Massimo Mascolo, Giuseppe Argenziano
No abstract text is available yet for this article.
June 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29766142/improving-life-expectancy-a-broken-neck-doesn-t-have-to-be-a-terminal-diagnosis-for-the-elderly
#4
Laura N Godat, Leslie M Kobayashi, David C Chang, Raul Coimbra
Background: Elderly patients with cervical spine fractures require optimal care. Treatment with a cervical collar or halo instead of surgical fixation may increase mortality. This investigation intends to describe the life expectancy after injury and evaluate the impact of surgical intervention on mortality. Methods: Patients ≥65 years, with traumatic cervical spine fractures without cord injury were identified in the 1995-2009 California Office of Statewide Health and Planning database...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29765800/surface-characterization-of-nanoparticles-using-near-field-light-scattering
#5
Eunsoo Yoo, Yizhong Liu, Chukwuazam A Nwasike, Sebastian R Freeman, Brian C DiPaolo, Bernardo Cordovez, Amber L Doiron
The effect of nanoparticle surface coating characteristics on colloidal stability in solution is a critical parameter in understanding the potential applications of nanoparticles, especially in biomedicine. Here we explored the modification of the surface of poly(ethylene glycol)-coated superparamagnetic iron oxide nanoparticles (PEG-SPIOs) with the synthetic pseudotannin polygallol via interpolymer complexation (IPC). Changes in particle size and zeta potential were indirectly assessed via differences between PEG-SPIOs and IPC-SPIOs in particle velocity and scattering intensity using near-field light scattering...
2018: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/29765713/different-packing-motifs-of-isomeric-e-n-halo-phenyl-methyl-idene-n-methyl-2-thio-phen-2-yl-acetohydrazides-controlled-by-c-h%C3%A2-o-inter-actions
#6
Laura N F Cardoso, Thais C M Noguiera, James L Wardell, Marcus V N de Souza, William T A Harrison
The crystal structures of three isomeric ( E )- N '-(chloro-phenyl-methyl-idene)- N -methyl-2-(thio-phen-2-yl)acetohydrazides (C14 H13 ClN2 OS) are described, with the Cl atom in ortho (I), meta (III) and para (IV) positions in the benzene ring. The ortho -bromo derivative (II) (C14 H13 BrN2 OS), which is isostructural with its chloro congener (I), is also reported. Mol-ecules (I)-(III) have similar conformations, which approximate to l-shapes, as indicated by their N-C-C-Ct (t = thio-phene) torsion angles of -90...
March 1, 2018: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/29765637/the-cosmic-spiderweb-equivalence-of-cosmic-architectural-and-origami-tessellations
#7
Mark C Neyrinck, Johan Hidding, Marina Konstantatou, Rien van de Weygaert
For over 20 years, the term 'cosmic web' has guided our understanding of the large-scale arrangement of matter in the cosmos, accurately evoking the concept of a network of galaxies linked by filaments. But the physical correspondence between the cosmic web and structural engineering or textile 'spiderwebs' is even deeper than previously known, and also extends to origami tessellations. Here, we explain that in a good structure-formation approximation known as the adhesion model, threads of the cosmic web form a spiderweb, i...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29761895/blurry-halos-after-tattooing-tattoo-blow-out-a-review-of-16-cases
#8
Nicolas Kluger
"Tattoo blow-out" (TBO) refers to the diffusion of tattoo inks deep in the hypodermis [1]. TBO presents as an asymptomatic, permanent, blurry halo of colour around the tattoo. It is rapidly visible after tattooing, but mistaken initially as a hematoma. It is only weeks after when the tattoo is healed that the customer starts to be concerned. This article is protected by copyright. All rights reserved.
May 15, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29760786/ultrasound-criteria-for-risk-stratification-of-thyroid-nodules-in-the-previously-iodine-deficient-area-of-austria-a-single-centre-retrospective-analysis
#9
Christina Tugendsam, Veronika Petz, Wolfgang Buchinger, Brigitta Schmoll-Hauer, Iris Pia Schenk, Karin Rudolph, Michael Krebs, Georg Zettinig
Background: We aimed to study the validity of six published ultrasound criteria for risk stratification of thyroid nodules in the former severely iodine deficient population of Austria. Methods: Retrospective, single centre, observer blinded study design. All patients with a history of thyroidectomy due to nodules seen in the centre between 2004 and 2014 with preoperative in-house sonography and documented postoperative histology were analyzed ( n  = 195). A board of five experienced thyroidologists evaluated the images of 45 papillary carcinomas, 8 follicular carcinomas, and 142 benign nodules regarding the following criteria: mild hypoechogenicity, marked hypoechogenicity, microlobulated or irregular margins, microcalcifications, taller than wide shape, missing thin halo...
2018: Thyroid Research
https://www.readbyqxmd.com/read/29759685/evaluation-of-the-small-aperture-intracorneal-inlay-three-year-results-from-the-cohort-of-the-u-s-food-and-drug-administration-clinical-trial
#10
John A Vukich, Daniel S Durrie, Jay S Pepose, Vance Thompson, Corina van de Pol, Ling Lin
PURPOSE: To evaluate the safety and effectiveness of the Kamra small-aperture intracorneal inlay. SETTING: Centers in North America, Europe, Asia, and Australia. DESIGN: Prospective clinical trial. METHODS: Patients with emmetropic presbyopia had intracorneal implantation of the inlay in the nondominant eye. RESULTS: The study comprised 507 patients with emmetropic presbyopia who were aged 45 to 60 years old...
May 11, 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29758704/density-profiles-of-a-self-gravitating-lattice-gas-in-one-two-and-three-dimensions
#11
Benaoumeur Bakhti, Divana Boukari, Michael Karbach, Philipp Maass, Gerhard Müller
We consider a lattice gas in spaces of dimensionality D=1,2,3. The particles are subject to a hardcore exclusion interaction and an attractive pair interaction that satisfies Gauss' law as do Newtonian gravity in D=3, a logarithmic potential in D=2, and a distance-independent force in D=1. Under mild additional assumptions regarding symmetry and fluctuations we investigate equilibrium states of self-gravitating material clusters, in particular radial density profiles for closed and open systems. We present exact analytic results in several instances and high-precision numerical data in others...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29757742/single-image-dehazing-using-color-ellipsoid-prior
#12
Trung Minh Bui, Wonha Kim
In this paper, we propose a new single-image dehazing method. The proposed method constructs color ellipsoids that are statistically fitted to haze pixel clusters in RGB space and then calculates the transmission values through color ellipsoid geometry. The transmission values generated by the proposed method maximize the contrast of dehazed pixels, while preventing over-saturated pixels. The values are also statistically robust because they are calculated from the averages of the haze pixel values. Furthermore, rather than apply a highly complex refinement process to reduce halo or unnatural artifacts, we embed a fuzzy segmentation process into the construction of the color ellipsoid so that the proposed method simultaneously executes the transmission calculation and the refinement process...
February 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29757146/imaging-of-pathology-involving-the-space-around-the-hepatic-veins-perivenous-pattern
#13
Ali Devrim Karaosmanoğlu, Mehmet Ruhi Onur, Mustafa Nasuh Özmen, Deniz Akata, Muşturay Karçaaltıncaba
We aimed to illustrate diseases involving the potential space around the hepatic veins. Perivenous halo sign can be seen in patients with congestive heart failure or fluid overload. Perivenous involvement can be observed in patients with alcoholic fatty liver disease, which can be focal or diffuse. Metastasis and primary liver tumor spread can also involve this space most likely due to involvement of lymphatics around hepatic veins.
March 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29755239/type-iii-odontoid-fractures-a-subgroup-analysis-of-complex-high-energy-fractures-treated-with-external-immobilization
#14
Thomas E Niemeier, Adam R Dyas, Sakthivel R Manoharan, Steven M Theiss
Study Design: Retrospective cohort study. Objective: Type III odontoid fractures are classically treated nonoperatively, yet, the current literature on Type III odontoid fractures includes fractures of multiple etiologies and fracture morphologies. We hypothesize that a subgroup of complex, Type III fractures caused by high-energy mechanisms are more likely to fail nonoperative treatment. Materials and Methods: Acute Type III odontoid fractures were identified at a single institution from 2008 to 2015...
January 2018: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29754839/-retrospective-study-of-25-cases-of-pulmonary-mucormycosis-in-acute-leukaemia
#15
REVIEW
D Caillot, C Legouge, I Lafon, E Ferrant, P B Pagès, A Plocque, L Estivalet, S Valot, F Dalle, H Abou Hanna, M-L Chretien
INTRODUCTION: In acute leukaemia (AL), the occurrence of pulmonary mucormycosis (PM), the incidence of which is increasing, as a result of chemotherapy induced marrow aplasia, remains a life threatening complication. METHODS: Analysis of clinical, biological and thoracic CT characteristics of patients with PM developing during the treatment of AL between 2000 and 2015. Day 0 (D0) was defined as the day with first CT evidence of PM. RESULTS: Among 1193 patients, 25 cases of PM were recorded during 2099 episodes of bone marrow aplasia...
May 10, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29751676/novel-guanidine-compound-against-multidrug-resistant-cystic-fibrosis-associated-bacterial-species
#16
Aamer Saeed, Alejandra Bosch, Marisa Bettiol, Diana L Nossa González, Mauricio Federico Erben, Yanina Lamberti
Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents to combat these infections. In this work, a small library comprising thiourea and guanidine derivatives with low molecular weight was designed; these derivatives were studied as antimicrobial agents against Gram-positive, Gram-negative, and a panel of drug-resistant clinical isolates recovered from patients with CF...
May 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29741410/management-of-resistant-halo-nevi
#17
Sherif S Awad, Rasha Ta Abdel Aziz, Sahar S Mohammed
BACKGROUND: Halo nevus (HN) is a rare dermatologic disorder characterized by typical whitish rim surrounding an existing melanocytic nevus resembling halo. It is a cosmetic problem that may be linked to vitiligo, and it is advised to remove these nevi in order to avoid development of vitiligo. OBJECTIVES: The aim of the present study is to evaluate the cosmetic outcome after nevus removal and leukoderma dermabrasion with epithelial graft followed by narrow-band ultraviolet B (NB-UVB) phototherapy as management of resistant halo nevi and avoidance of development of vitiligo...
May 9, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29737108/-clinical-and-ultrasonographic-features-of-hepatic-infantile-hemangioendothelioma
#18
Hong Wang, Huan Zhang, Ting-Ting Qiu, Yu-Lan Peng
OBJECTIVE: To investigate the clinical manifestations and ultrasound features of hepatic infantile hemangioendothelioma (IHE). METHODS: This study retrospectively analyzed the clinical features and ultrasound characteristics of 8 patients of IHE,whose diagnosis was confirmed by surgery or liver biopsy from January 2010 to October 2016. RESULTS: Among the eight IHE patients,the male-to-female ratio was 1:1,with the mean age ranged from 15 d to 3 yr...
January 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29728464/quantum-oscillations-in-a-biaxial-pair-density-wave-state
#19
M R Norman, J C Séamus Davis
There has been growing speculation that a pair density wave state is a key component of the phenomenology of the pseudogap phase in the cuprates. Recently, direct evidence for such a state has emerged from an analysis of scanning tunneling microscopy data in halos around the vortex cores. By extrapolation, these vortex halos would then overlap at a magnetic-field scale where quantum oscillations have been observed. Here, we show that a biaxial pair density wave state gives a unique description of the quantum oscillation data, bolstering the case that the pseudogap phase in the cuprates may be a pair density wave state...
May 4, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29728338/carotenoid-production-in-sugarcane-juice-and-synthetic-media-supplemented-with-nutrients-by-rhodotorula-rubra-l02
#20
Mariana de Paula Bonadio, Lidyane Aline de Freita, Márcia Justino Rossini Mutton
In order for the use of biological carotenoids to become feasible, it is necessary to have adequate low cost sources and improved methods of cultivation. The aim of this study was to evaluate the effect of supplementation with nitrogen, phosphorus, zinc, and magnesium, on the biomass and carotenoid volumetric production by yeast Rhodotorula rubra L02 using a complex medium (sugarcane juice) and synthetic media (sucrose and maltose) as substrates. The experimental design used for each substrate was randomized in blocks with 16 treatments and 3 repetitions...
April 25, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
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