keyword
https://read.qxmd.com/read/38694831/evaluation-of-the-departmental-inter-rater-reliability-when-scoring-thyroid-nodules-according-to-the-british-thyroid-association-ultrasound-classification-model-is-there-significant-disagreement
#1
JOURNAL ARTICLE
Nabil Rtam
INTRODUCTION: The British Thyroid Association Ultrasound-classification is a risk stratification model which grades thyroid nodules in U2-5 based on their sonographic appearance. Existence of variability between the ultrasound operators when U-scoring is reported in the literature with some evidence found in the author's department. The aim of this study was to investigate whether there is significant disagreement in the department and identify potential reasons for variability. METHODS: Eight operators, radiologists and sonographers, were recruited to grade 33 TNs and answer a tick box questionnaire using the British Thyroid Association lexicon...
May 2024: Ultrasound: Journal of the British Medical Ultrasound Society
https://read.qxmd.com/read/38692958/evaluation-of-micronuclei-cytomorphometric-and-cytologic-changes-of-the-oral-mucosa-in-hookah-and-cigarette-smokers
#2
JOURNAL ARTICLE
Elvira Antonieta Sepulveda Inostroza, Adriano Bressane, Lígia Ângelo Tavares Schwarzmeier, Ester Borges Lacerda, Karine Rodrigues Dos Anjos, Thamires Soares Procópio Dos Santos, Desiree Rosa Cavalcanti, Fábio Dupart Nascimento, Janete Dias Almeida, Mônica Ghislaine Oliveira Alves
OBJECTIVE: To analyze the effect of hookah and cigarettes on the oral mucosa of smokers through the use of exfoliative cytology. STUDY DESIGN: Smear samples were collected by exfoliative cytology from the tongue of 33 hookah smokers, 22 cigarette smokers, and 30 non-smokers. The selected analyses include micronuclei (MN), metanuclear anomalies, epithelial maturation, and cytomorphology (nuclear area [NA], cytoplasmic area [CA], and NA/CA ratio). RESULTS: The largest differences observed for MN and metanuclear anomalies were between cigarette smokers and the control group (notably 1 MN P = ...
March 28, 2024: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://read.qxmd.com/read/38690722/synthesis-antifungal-evaluation-2d-quantitative-structure-activity-relationship-and-molecular-docking-studies-of-isoxazole-derivatives-as-potential-fungicides
#3
JOURNAL ARTICLE
Kailashpati Tripathi, Parshant Kaushik, Dinesh Kumar Yadav, Rakesh Kumar, Sameer Ranjan Misra, Rajni Godara, Bishnu Maya Bashyal, Virendra Singh Rana, Rajesh Kumar, Jagdish Yadav, Najam Akhtar Shakil
BACKGROUND: Sheath blight and bakanae disease, prominent among emerging rice ailments, exert a profound impact on rice productivity, causing severe impediments to crop yield. Excessive use of older fungicides may lead to the development of resistance in the pathogen. Indeed, a pressing and immediate need exists for novel, low-toxicity and highly selective fungicides that can effectively combat resistant fungal strains RESULTS: A series of 20 isoxazole derivatives were synthesized using alkoxy/halo acetophenones and N,N-dimethylformamidedimethylacetal...
May 1, 2024: Pest Management Science
https://read.qxmd.com/read/38690360/functional-domains-of-acinetobacter-bacteriophage-tail-fibers
#4
JOURNAL ARTICLE
Danielle L Peters, Francis Gaudreault, Wangxue Chen
A rapid increase in antimicrobial resistant bacterial infections around the world is causing a global health crisis. The Gram-negative bacterium Acinetobacter baumannii is categorized as a Priority 1 pathogen for research and development of new antimicrobials by the World Health Organization due to its numerous intrinsic antibiotic resistance mechanisms and ability to quickly acquire new resistance determinants. Specialized phage enzymes, called depolymerases, degrade the bacterial capsule polysaccharide layer and show therapeutic potential by sensitizing the bacterium to phages, select antibiotics, and serum killing...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38683002/precision-mass-measurement-of-the-proton-dripline-halo-candidate-22-al
#5
JOURNAL ARTICLE
S E Campbell, G Bollen, B A Brown, A Dockery, C M Ireland, K Minamisono, D Puentes, B J Rickey, R Ringle, I T Yandow, K Fossez, A Ortiz-Cortes, S Schwarz, C S Sumithrarachchi, A C C Villari
We report the first mass measurement of the proton-halo candidate ^{22}Al performed with the low energy beam ion trap facility's 9.4 T Penning trap mass spectrometer at facility for rare isotope beams. This measurement completes the mass information for the lightest remaining proton-dripline nucleus achievable with Penning traps. ^{22}Al has been the subject of recent interest regarding a possible halo structure from the observation of an exceptionally large isospin asymmetry [J. Lee et al., Large isospin asymmetry in Si22/O22 Mirror Gamow-Teller transitions reveals the halo structure of ^{22}Al, Phys...
April 12, 2024: Physical Review Letters
https://read.qxmd.com/read/38681944/treatment-of-post-burn-leucoderma-with-superficial-dermabrasion-followed-by-suction-blister-epidermal-grafting-a-clinical-prospective-study
#6
JOURNAL ARTICLE
A S Ali, W H Mahmoud, M I Elsawaf, N Elmelegy
Post-burn leucoderma patients remain the most challenging to treat because they have two distinct issues: textural changes and hypopigmentation that must be managed simultaneously. A variety of surgical techniques have been used with variable outcome. This prospective study evaluated the efficacy of superficial dermabrasion followed by suction blister epidermal grafting (SBEG) in post-burn leucoderma treatment. Twenty patients, 15 females and 5 males, ages ranging from 18 to 52 years, all having post-burn leucoderma ranging from 10 to 36 months, were included...
June 2023: Annals of Burns and Fire Disasters
https://read.qxmd.com/read/38680572/nrhfluors-quantitative-revealing-the-interaction-between-protein-homeostasis-and-mitochondria-dysfunction-via-fluorescence-lifetime-imaging
#7
JOURNAL ARTICLE
Yubo Huang, Meiyi Chang, Xiaochen Gao, Jiabao Fang, Wenjing Ding, Jiachen Liu, Baoxing Shen, Xin Zhang
Degenerative diseases are closely related to the changes of protein conformation beyond the steady state. The development of feasible tools for quantitative detection of changes in the cellular environment is crucial for investigating the process of protein conformational variations. Here, we have developed a near-infrared AIE probe based on the rhodamine fluorophore, which exhibits dual responses of fluorescence intensity and lifetime to local viscosity changes. Notably, computational analysis reveals that NRhFluors fluorescence activation is due to inhibition of the RACI mechanism in viscous environment...
April 24, 2024: ACS Central Science
https://read.qxmd.com/read/38679600/first-report-of-phyllosticta-capitalensis-causing-leaf-spot-in-hymenocallis-littoralis-in-china
#8
JOURNAL ARTICLE
Mei Qing Wu, Chao Zheng, Yue Lian Liu
Hymenocallis littoralis (Jacq.) Salisb. is a common ornamental plant in China. In November 2021, leaf spots were observed on H. littoralis in a public garden in Zhanjiang, Guangdong Province, China (21°17'25″N, 110°18'12″E). Disease incidence was around 60% (n = 100 investigated plants from about 1 ha). Leaf symptoms were round spots with collapse centers, surrounded by yellow halos. Ten symptomatic leaves from 10 plants were sampled. The margins of the samples were cut into 2 mm × 2 mm pieces...
April 28, 2024: Plant Disease
https://read.qxmd.com/read/38679589/first-report-of-leaf-blight-caused-by-nigrospora-hainanensis-on-euonymus-japonicus-in-china
#9
JOURNAL ARTICLE
Xianxi Ao, Shasha Deng, Wenjia Yang, Ruidong Fan, Ting Shi, Zerui Feng, Xiaoyulong Chen
Euonymus japonicus Thunb., belonging to the family Celastreace and native to East Asia, is a widely cultivated evergreen ornamental woody plant with important ecological and economic values. In May 2023, serious leaf blight of E. japonicus occurred in the campus green space at Guiyang University, Guizhou Province, China (26°55'85"N, 106°78'04"E). Early symptom appeared as small, circular light brown spots on the edges or tips of the leaves. Then, the spot developed visible necrosis, initially light brown to dark brown halos with clear margins...
April 28, 2024: Plant Disease
https://read.qxmd.com/read/38679442/ankle-instability-facts-and-myths-to-protect-your-cartilage-repairing
#10
REVIEW
Yuhan Tan, Kristian Buedts
The majority of patients with an osteochondral lesion of the talus (OLT) report a history of trauma. Therefore, it is important to assess for concomitant ankle instability when dealing with patients with a symptomatic OLT. The History; Alignment; Ligaments; Others "(HALO)" approach can be a helpful tool in the evaluation of patients with an OLT. If conservative treatment fails, surgery may be indicated. Although there is a lack of comparative studies investigating the effect of stabilization procedures on cartilage repair, we believe that addressing instability is a key factor in improving patient outcome...
June 2024: Foot and Ankle Clinics
https://read.qxmd.com/read/38674544/antibiotic-resistance-in-plant-pathogenic-bacteria-recent-data-and-environmental-impact-of-unchecked-use-and-the-potential-of-biocontrol-agents-as-an-eco-friendly-alternative
#11
REVIEW
Tarequl Islam, Md Azizul Haque, Hasi Rani Barai, Arif Istiaq, Jong-Joo Kim
The economic impact of phytopathogenic bacteria on agriculture is staggering, costing billions of US dollars globally. Pseudomonas syringae is the top most phytopathogenic bacteria, having more than 60 pathovars, which cause bacteria speck in tomatoes, halo blight in beans, and so on. Although antibiotics or a combination of antibiotics are used to manage infectious diseases in plants, they are employed far less in agriculture compared to human and animal populations. Moreover, the majority of antibiotics used in plants are immediately washed away, leading to environmental damage to ecosystems and food chains...
April 18, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38672812/front-of-package-protein-labels-on-cereal-create-health-halos
#12
JOURNAL ARTICLE
Gina Pope McKeon, William K Hallman
Front-of-package protein labels are frequently added to breakfast cereals, aimed at increasing purchases by consumers who believe they would benefit from eating more protein. However, the overall nutritional compositions of such products are often not significantly better than similar products without protein labels, and may contain more sugar, sodium, and calories to improve taste. We conducted an online survey with 1022 US adults to examine consumer perceptions of two cereals (Special K Original and Special K Protein)...
April 9, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38671381/comparatively-analysing-the-postoperative-optical-performance-of-different-intraocular-lenses-a-prospective-observational-study
#13
COMPARATIVE STUDY
Shuanglin Guo, Hao Huang, Bowen Li, Mansha Huang, Lu Gao, Jingyi Chen, Yuying Zeng, Ye Yang, Lin Liu, Lu Cheng, Siyang Yao, Hao Cheng
BACKGROUND: Postoperative performance, including best corrected distance visual acuity (BCDVA) and optical metrics (from the OQAS and iTrace devices), was compared among 4 different intraocular lenses (IOLs). METHODS: This prospective observational study included 104 eyes from 104 subjects who underwent cataract surgery combined with implantation of 4 different IOLs: monofocal (Mon) IOLs, segmental refractive (SegRef) IOLs, diffractive (Dif) IOLs and extended depth of focus (EDoF) IOLs...
April 26, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38669565/synthesis-of-borylated-aminomethyl-cyclopropanes-using-c-1-bisnucleophiles
#14
JOURNAL ARTICLE
Tyler R McDonald, Julia A Turner, Alexis L Gabbey, Prathulesh Balasubramanian, Sophie A L Rousseaux
Lithiated 1,1-diborylalkanes have been used as nucleophilic coupling partners with a range of oxygen-based electrophiles, including esters, carbonyls, and epoxides. However, their reactivity with nitrogen-based electrophiles, such as aziridines, has remained relatively understudied. Herein, we show that lithiated 1,1-diborylalkanes react with α-halo and α-tosyl aziridines to yield borylated (aminomethyl)cyclopropanes-a privileged scaffold within medicinal chemistry. The reaction displays high levels of diastereoselectivity, enabling careful control of up to three stereocenters within a single transformation...
April 26, 2024: Organic Letters
https://read.qxmd.com/read/38667863/non-thermal-solar-wind-electron-velocity-distribution-function
#15
JOURNAL ARTICLE
Peter H Yoon, Rodrigo A López, Chadi S Salem, John W Bonnell, Sunjung Kim
The quiet-time solar wind electrons feature non-thermal characteristics when viewed from the perspective of their velocity distribution functions. They typically have an appearance of being composed of a denser thermal "core" population plus a tenuous energetic "halo" population. At first, such a feature was empirically fitted with the kappa velocity space distribution function, but ever since the ground-breaking work by Tsallis, the space physics community has embraced the potential implication of the kappa distribution as reflecting the non-extensive nature of the space plasma...
March 30, 2024: Entropy
https://read.qxmd.com/read/38660898/-a-cross-sectional-study-on-the-pathogen-composition-and-antimicrobial-resistance-in-neonates-with-sepsis-in-hebei-province-china
#16
JOURNAL ARTICLE
(no author information available yet)
OBJECTIVES: To study the pathogen composition and antimicrobial resistance characteristics in neonates with sepsis in the Hebei area, providing a basis for optimizing the management strategies for neonatal sepsis in the region. METHODS: The medical data of neonates with sepsis confirmed by blood culture from 23 hospitals in Hebei Province were collected prospectively from November 1, 2021 to December 31, 2022. The pathogen composition and antimicrobial resistance characteristics were analyzed in early-onset sepsis (EOS), community-acquired late-onset sepsis (CALOS), and hospital-acquired late-onset sepsis (HALOS) cases...
April 15, 2024: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/38654601/stereoselective-synthesis-of-gem-dihalopiperidines-via-the-halo-aza-prins-cyclization-reaction-access-to-piperidin-4-ones-and-pyridines
#17
JOURNAL ARTICLE
Surjya Kumar Bora, Subhamoy Biswas, Bipin Kumar Behera, Anil K Saikia
An efficient methodology for the synthesis of 4,4-dihalopiperidine derivatives in excellent yields has been developed using N -(3-halobut-3-en-1-yl)-4-methylbenzenesulfonamide and an aldehyde catalyzed by In(OTf)3 . The reaction involves an initial formation of a six-membered carbocation via the aza-Prins cyclization reaction followed by a nucleophilic attack by a halide ion to give 4,4-dihalopiperidine. The dihalopiperidine is converted to tetrahydropiperidinone using Ac2 O/Et3 N in DCM/H2 O (1 : 1)...
April 24, 2024: Organic & Biomolecular Chemistry
https://read.qxmd.com/read/38653291/real-world-clinical-results-with-the-hoya-vivinex-impress-intraocular-lens-with-enhanced-depth-of-focus
#18
JOURNAL ARTICLE
Tamer Tandogan, Arnas Urbonavicius, Marco Langenegger, David Goldblum, Christoph Tappeiner
BACKGROUND: In cataract surgery, intraocular lenses (IOLs) with enhanced depth of focus are an option to correct presbyopia. The purpose of this quality assurance analysis was to evaluate visual acuity and patient satisfaction after implantation of the Hoya Vivinex Impress IOL. METHODS: The Hoya Vivinex Impress IOL was implanted in patients undergoing cataract surgery at the Pallas Klinik, Olten, Switzerland. Five weeks postoperatively, a clinical examination and a survey on patient satisfaction were conducted...
April 2024: Klinische Monatsblätter Für Augenheilkunde
https://read.qxmd.com/read/38653290/patient-reported-outcome-measures-proms-with-refractive-and-diffractive-extended-depth-of-focus-edof-intraocular-lenses
#19
JOURNAL ARTICLE
Shalini Banerjee, Claude Kaufmann, Chiara Tinner, Katja Iselin, Christoph Andreas Amstutz, Ying-Yu Melody Hedinger, Martin K Schmid, Michael Thiel
BACKGROUND: Extended depth of focus intraocular lenses (EDOF-IOLs) provide unaided far- and mid-range vision. Refractive IOLs, in contrast to diffractive designs, are associated with a lower depth of focus and absence of dysphotopsia. The aim of this study was to assess spectacle independence for far-range, mid-range, and near-vision activities in patients after implantation of refractive or diffractive EDOF-IOLs using patient-reported outcome measures (PROMs) in a real-world setting...
April 2024: Klinische Monatsblätter Für Augenheilkunde
https://read.qxmd.com/read/38650763/clinical-histopathological-and-radiological-profile-of-patients-presenting-with-thyroid-malignancies-among-the-kerala-population
#20
JOURNAL ARTICLE
Chandralal Prasannakumar Girijakumari, Arshad Koroth, Muhamed Fawas Abdul Rasheed, Azif Ali Usman, Shiraz Basheer, Mohamed Rasween Kareem
BACKGROUND AND OBJECTIVE: Thyroid cancer, though relatively uncommon among all cancer types, stands as the primary form of endocrine tumor. Over the last 20 years, there has been a significant uptick in its occurrence. Papillary thyroid carcinoma (PTC), which is well-differentiated, emerges as the dominant subtype, in regions where iodine levels are deemed adequate. The study aimed to study the clinicopathological profile of patients diagnosed with thyroid malignancies at the Muslim Educational Society (MES) Medical College Perinthalmanna...
March 2024: Curēus
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