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https://www.readbyqxmd.com/read/28741956/li13mn-seo3-8-lithium-rich-transition-metal-selenite-containing-jahn-teller-distortive-cations
#1
Hongil Jo, Seung Yoon Song, Eunjeong Cho, Jongho So, Suheon Lee, Kwang Yong Choi, Kang Min Ok
A novel lithium-rich transition metal selenite, Li13Mn(SeO3)8, that is composed of a Jahn-Teller distortive cation, Mn(3+), in the high spin d(4) state, and a second-order Jahn-Teller (SOJT) distortive lone pair cation, Se(4+), has been synthesized via hydrothermal and high temperature solid state reactions. The selenite is classified as a molecular compound consisting of MnO6 octahedra, SeO3 trigonal pyramids, and Li(+) cations. Considering the Li-O interactions, the structure of Li13Mn(SeO3)8 may be described as a pseudo-three-dimensional framework as well...
July 25, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28741374/lipid-emulsion-alleviates-the-vasodilation-and-mean-blood-pressure-decrease-induced-by-a-toxic-dose-of-verapamil-in-isolated-rat-aortae-and-an-in-vivo-rat-model
#2
S-H Ok, I-W Shin, S H Lee, J Park, M S Woo, J-M Hong, J Kim, J-T Sohn
This study aimed to examine the effects of lipid emulsion on the vasodilation and cardiovascular depression induced by toxic doses of calcium channel blockers. The effects of lipid emulsion on the vasodilation induced by bepridil, verapamil, nifedipine, and diltiazem were investigated in isolated endothelium-denuded rat aortae. The effect of lipid emulsion on the comparable hemodynamic depression induced by the continuous infusion of a toxic dose of either verapamil or diltiazem was examined in an in vivo rat model...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28739389/association-of-recent-major-psychological-stress-with-cardiac-arrest-a-case-control-study
#3
Seungmin Jeong, Ki Ok Ahn, Sang Do Shin, Kyoung Jun Song, Joo-Yeong Kim, Eui Jung Lee, Yu Jin Lee, Ki Jeong Hong, Young Sun Ro
OBJECTIVE: We hypothesized that major psychological stress can be a risk factor for cardiac arrest and that effects are modified by elapsed time from specific stressful events. METHODS: Case-control study was conducted using database for cardiac arrest and emergency department (ED) visiting. Cases included adult patients with cardiac arrest with presumed cardiac etiology. Controls were matched with sex and age and visiting day from unintentional injured patients in same ED...
July 13, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28737945/preliminary-pet-study-of-18-f-fc119s-in-normal-and-alzheimer-s-disease-models
#4
Se Jong Oh, Min Hwan Kim, Sang Jin Han, Kyung Jun Kang, In Ok Ko, YoungSoo Kim, Ji Ae Park, Jae Yong Choi, Kyo Chul Lee, Dae Yoon Chi, Yong Jin Lee, Kyeong Min Kim
To evaluate the efficacy of (18)F-FC119S as a positron emission tomography (PET) radiopharmaceutical for the imaging of Alzheimer's disease (AD), we studied the drug absorption characteristics and (18)F-FC119S distribution in normal mice. In addition, we evaluated the specificity of (18)F-FC119S for β-amyloid (Aβ) in the AD group of an APP/PS1 mouse model and compared it with that in the wild-type (WT) group. (18)F-FC119S exhibited the characteristics of rapid brain uptake and washout patterns in the normal mice...
July 24, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28736294/enhanced-neuroprotection-of-anthocyanin-loaded-peg-gold-nanoparticles-against-a%C3%AE-1-42-induced-neuroinflammation-and-neurodegeneration-via-the-nf-kb-jnk-gsk3%C3%AE-signaling-pathway
#5
Min Ju Kim, Shafiq Ur Rehman, Faiz Ul Amin, Myeong Ok Kim
Amyloid-beta (Aβ1-42) plaques and neurofibrillary tangles (NFTs) are the main hallmarks considered to be associated with neuroinflammation in Alzheimer's disease (AD). Recently, nanoparticle-based targeted drug delivery approaches have been found to be a useful tool in the neurotherapeutics field. Therefore, we examined and compared the neuroprotective effect of anthocyanins alone and anthocyanin-loaded poly (ethylene glycol)-gold nanoparticles (PEG-AuNPs) in Aβ1-42-injected mouse and in vitro models of AD...
July 20, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28735789/xp-shaper-a-novel-adaptive-core-rotary-instrument-micro-computed-tomographic-analysis-of-its-shaping-abilities
#6
Adham A Azim, Lucila Piasecki, Ulisses Xavier da Silva Neto, Alessandra Timponi Goes Cruz, Katharina A Azim
INTRODUCTION: The aim of this study was to investigate the shaping abilities of the XP Shaper (FKG, La Chaux-de-Fonds, Switzerland) and compare the findings with Vortex Blue (Dentsply Tulsa Dental Specialties, Tulsa, OK) using micro-computed tomographic imaging. METHODS: Twenty matched, extracted, mandibular, central incisors with a single, oval canal were scanned preoperatively at 25-μm resolution and postoperatively after instrumentation with either Vortex Blue in a crown-down manner up to size 30...
July 20, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28734654/schlafen-14-slfn14-is-a-novel-antiviral-factor-involved-in-the-control-of-viral-replication
#7
Rak-Kyun Seong, Seong-Wook Seo, Ji-Ae Kim, Sarah J Fletcher, Neil V Morgan, Mukesh Kumar, Young-Ki Choi, Ok Sarah Shin
Schlafen (SLFN) proteins have been suggested to play important functions in cell proliferation and immune cell development. In this study, we determined the antiviral activities of putative RNA-helicase domain-containing SLFN14. Murine SLFN14 expression was specifically induced by TLR3-mediated pathways and type I interferon (IFN) in RAW264.7 mouse macrophages. To examine the role of SLFN during viral infection, cells were infected with either wild-type PR8 or delNS1/PR8 virus. SLFN14 expression was specifically induced following influenza virus infection...
July 11, 2017: Immunobiology
https://www.readbyqxmd.com/read/28732383/radiation-alters-pd-l1-nkg2d-ligand-levels-in-lung-cancer-cells-and-leads-to-immune-escape-from-nk-cell-cytotoxicity-via-il-6-mek-erk-signaling-pathway
#8
Ming Jing Shen, Li Jun Xu, Li Yang, Ying Tsai, Peter C Keng, Yongbing Chen, Soo Ok Lee, Yuhchyau Chen
We investigated whether radiation influences the susceptibility of non-small cell lung cancer (NSCLC) cells to NK cell mediated cytotoxicity. We found radiation treatment increased expression of programmed cell death ligand 1 (PD-L1), but decreased NK group 2, member D (NKG2D) ligand expressions in A549 and H157 NSCLC cells. Both types of changes would have protected tumor cells from the cytotoxic action of NK cells. Consistently, we detected similar alteration in these molecules in radioresistant A549R26-1 and H157R24-1 subline cells...
July 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732261/predictors-of-disclosure-management-behavior-at-the-end-of-1-year-follow-up-in-korean-adults-with-newly-diagnosed-epilepsy
#9
Sang-Ahm Lee, Soon-Kee No, Hyungkook Park, Ok-Joon Kim, Jee-Hyun Kwon, Ji-Yeon Ryu, Sang-Moo Lee, Kwang-Deog Jo
PURPOSE: Epilepsy is a concealable stigmatizing condition. We investigated the factors predicting disclosure management behavior in Korean adults with newly diagnosed epilepsy. METHODS: This longitudinal multicenter study included Korean adults with newly diagnosed epilepsy. Using statistical analyses, we determined at the end of a 1-year follow-up whether Disclosure Management Scale (DMS) scores were predicted by demographic, clinical, and psychosocial variables, including felt stigma, stress coping style, personality traits, social support, and experienced discrimination from society...
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732078/impact-of-diabetes-mellitus-on-indeterminate-results-of-the-quantiferon-tb-gold-in-tube-test-a-propensity-score-matching-analysis
#10
Hong-Joon Shin, Tae-Ok Kim, Hyung-Joo Oh, Ha-Young Park, Jin-Sun Chang, Seong Ahn, Yu-Il Kim, Sung-Chul Lim, Yong-Soo Kwon
BACKGROUND: The sensitivity of interferon-gamma release assays (IGRAs) in the detection of Mycobacterium tuberculosis infection could be affected by conditions of immune dysregulation. For this reason, diabetes mellitus (DM) may increase the frequency of indeterminate results of IGRAs. However, there have been inconsistent reports of role of DM on indeterminate IGRA results. METHODS: We retrospectively reviewed all patients who underwent QuantiFERON-TB Gold In-Tube testing (QFT-GIT) at Chonnam National University Hospital...
2017: PloS One
https://www.readbyqxmd.com/read/28730411/sugary-endosperm-is-modulated-by-starch-branching-enzyme-iia-in-rice-oryza-sativa-l
#11
Yunjoo Lee, Min-Seon Choi, Gileung Lee, Su Jang, Mi-Ra Yoon, Backki Kim, Rihua Piao, Mi-Ok Woo, Joong Hyoun Chin, Hee-Jong Koh
BACKGROUND: Starch biosynthesis is one of the most important pathways that determine both grain quality and yield in rice (Oryza sativa L.). Sugary endosperm, sugary-1 (sug-1), is a mutant trait for starch biosynthesis. Rice plants carrying sug-1 produce grains that accumulate water-soluble carbohydrates instead of starch, even after maturity. Although this trait enhances the diversity of grain quality, sugary endosperm rice has hardly been commercialized due to the severely wrinkled grains and subsequent problems in milling...
December 2017: Rice
https://www.readbyqxmd.com/read/28726609/influenza-d-virus-in-animal-species-in-guangdong-province-southern-china
#12
Shao-Lun Zhai, He Zhang, Sheng-Nan Chen, Xia Zhou, Tao Lin, Runxia Liu, Dian-Hong Lv, Xiao-Hui Wen, Wen-Kang Wei, Dan Wang, Feng Li
Molecular tests revealed influenza D viruses of D/OK lineage widely circulating in farmed animal species in Guangdong Province, southern China. In particular, we found high levels of influenza D virus infection in goats and pigs. We also detected viral RNA in serum specimens and feces of animals with certain severe diseases.
August 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28725337/complete-genome-sequence-of-leuconostoc-suionicum-dsm-20241-t-provides-insights-into-its-functional-and-metabolic-features
#13
Byung Hee Chun, Se Hee Lee, Hye Hee Jeon, Dong-Woon Kim, Che Ok Jeon
The genome of Leuconostoc suionicum DSM 20241(T) (=ATCC 9135(T) = LMG 8159(T) = NCIMB 6992(T)) was completely sequenced and its fermentative metabolic pathways were reconstructed to investigate the fermentative properties and metabolites of strain DSM 20241(T) during fermentation. The genome of L. suionicum DSM 20241(T) consists of a circular chromosome (2026.8 Kb) and a circular plasmid (21.9 Kb) with 37.58% G + C content, encoding 997 proteins, 12 rRNAs, and 72 tRNAs. Analysis of the metabolic pathways of L...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/28723549/interleukin-7-availability-is-maintained-by-a-hematopoietic-cytokine-sink-comprising-innate-lymphoid-cells-and-t%C3%A2-cells
#14
Christopher E Martin, Darina S Spasova, Kwesi Frimpong-Boateng, Hee-Ok Kim, Minji Lee, Kwang Soon Kim, Charles D Surh
Interleukin-7 (IL-7) availability determines the size and proliferative state of the resting T cell pool. However, the mechanisms that regulate steady-state IL-7 amounts are unclear. Using experimental lymphopenic mouse models and IL-7-induced homeostatic proliferation to measure IL-7 availability in vivo, we found that radioresistant cells were the source of IL-7 for both CD4(+) and CD8(+) T cells. Hematopoietic lineage cells, although irrelevant as a source of IL-7, were primarily responsible for limiting IL-7 availability via their expression of IL-7R...
July 18, 2017: Immunity
https://www.readbyqxmd.com/read/28722024/multifunctional-nanoparticles-as-a-tissue-adhesive-and-an-injectable-marker-for-image-guided-procedures
#15
Kwangsoo Shin, Jin Woo Choi, Giho Ko, Seungmin Baik, Dokyoon Kim, Ok Kyu Park, Kyoungbun Lee, Hye Rim Cho, Sang Ihn Han, Soo Hong Lee, Dong Jun Lee, Nohyun Lee, Hyo-Cheol Kim, Taeghwan Hyeon
Tissue adhesives have emerged as an alternative to sutures and staples for wound closure and reconnection of injured tissues after surgery or trauma. Owing to their convenience and effectiveness, these adhesives have received growing attention particularly in minimally invasive procedures. For safe and accurate applications, tissue adhesives should be detectable via clinical imaging modalities and be highly biocompatible for intracorporeal procedures. However, few adhesives meet all these requirements. Herein, we show that biocompatible tantalum oxide/silica core/shell nanoparticles (TSNs) exhibit not only high contrast effects for real-time imaging but also strong adhesive properties...
July 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/28721511/molecular-and-phylogenetic-characterization-of-bovine-coronavirus-virus-isolated-from-dairy-cattle-in-central-region-thailand
#16
Kanokwan Singasa, Taweesak Songserm, Preeda Lertwatcharasarakul, Pipat Arunvipas
Bovine coronavirus (BCoV) is involved mainly in enteric infections in cattle. This study reports the first molecular detection of BCoV in a diarrhea outbreak in dairy cows in the Central Region, Thailand. BCoV was molecularly detected from bloody diarrheic cattle feces by using nested PCR. Agarose gel electrophoresis of three diarrheic fecal samples yielded from the 25 samples desired amplicons that were 488 base pairs and sequencing substantiated that have BCoV. The sequence alignment indicated that nucleotide and amino acid sequences, the three TWD isolated in Thailand, were more quite homologous to each other (amino acid at position 39 of TWD1, TWD3 was proline, but TWD2 was serine) and closely related to OK-0514-3strain (virulent respiratory strain; RBCoV)...
July 18, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28718822/a-bacterial-toxin-with-analgesic-properties-hyperpolarization-of-drg-neurons-by-mycolactone
#17
Ok-Ryul Song, Han-Byul Kim, Samuel Jouny, Isabelle Ricard, Alexandre Vandeputte, Nathalie Deboosere, Estelle Marion, Christophe J Queval, Pierre Lesport, Emmanuel Bourinet, Daniel Henrion, Seog Bae Oh, Guillaume Lebon, Guillaume Sandoz, Edouard Yeramian, Laurent Marsollier, Priscille Brodin
Mycolactone, a polyketide molecule produced by Mycobacterium ulcerans, is the etiological agent of Buruli ulcer. This lipid toxin is endowed with pleiotropic effects, presents cytotoxic effects at high doses, and notably plays a pivotal role in host response upon colonization by the bacillus. Most remarkably, mycolactone displays intriguing analgesic capabilities: the toxin suppresses or alleviates the pain of the skin lesions it inflicts. We demonstrated that the analgesic capability of mycolactone was not attributable to nerve damage, but instead resulted from the triggering of a cellular pathway targeting AT₂ receptors (angiotensin II type 2 receptors; AT₂R), and leading to potassium-dependent hyperpolarization...
July 18, 2017: Toxins
https://www.readbyqxmd.com/read/28717853/radiation-related-heart-disease-after-breast-cancer-radiation-therapy-in-korean-women
#18
Jee Suk Chang, Byung Kyun Ko, Jeoung Won Bae, Jong-Han Yu, Min Ho Park, Yongsik Jung, Ye Won Jeon, Kyung Hwan Kim, Jaeyong Shin, Chang-Ok Suh, Yong Bae Kim
PURPOSE: To study the late cardiac toxicity of breast radiation therapy (RT) in Asian women. METHODS: Female breast cancer patients in Korea who underwent breast conservation surgery followed by RT from 1990-2012 were identified from two large registries at institution and population levels. Cumulative incidences of acute coronary events (ACE) or cardiac mortality were estimated in relation to the laterality of breast cancer using a competing risks analysis. RESULTS: In an analysis of 2577 women from a single institution, 3...
July 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28717073/interstitial-lung-disease-after-pleurodesis-for-malignant-pleural-effusion
#19
Norihito Yokoe, Eisuke Katsuda, Kenshi Kosaka, Rie Hamanaka, Ayako Matsubara, Masaki Nishimura, Hiroyuki Tanaka, Nobuhiro Asai, Ayumu Takahashi, Toshiki Kawamura, Tsuneo Ishiguchi, Etsuro Yamaguchi, Akihito Kubo
Objective Pleurodesis is an effective therapy for malignant pleural effusion (MPE). While interstitial lung disease (ILD) has been regarded as a serious complication of pleurodesis, its clinicopathological characteristics have not been fully understood. This study was conducted to elucidate the incidence of ILD and the risk factors for ILD in patients who underwent pleurodesis to control MPE. Methods The medical records of patients who underwent pleurodesis in Aichi Medical University between March 2008 and February 2013, the period before the approval of talc in Japan, were retrospectively analyzed...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28714114/split-liver-transplantation-for-retroperitoneal-immature-teratoma-masquerading-as-hepatoblastoma
#20
Dongkyu Oh, Nam-Joon Yi, Sanghee Song, Ok Kyung Kim, Suk Kyun Hong, Kyung Chul Yoon, Sung Woo Ahn, Hyo-Sin Kim, Hyeyoung Kim, Hyun-Young Kim, Hyoung Jin Kang, Myungsu Lee, Kyoung Bun Lee, Kwang-Woong Lee, Kyung Suk Suh
Extragonadal teratoma originating from the retroperitoneum represents less than 5% of all teratomas and accounts for less than 10% of all pediatric retroperitoneal neoplasms. To date, there has been no report of teratoma managed with LT. This study reports an infant aged 3 months with retroperitoneal immature teratoma involving the hepatic hilum, refractory to chemotherapy and treated with LT. The patient was referred to our hospital for management of a growing abdominal mass. Histopathology of a fine needle biopsy of the lesion suggested the possibility of a hepatoblastoma with teratoid features...
July 16, 2017: Pediatric Transplantation
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