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https://www.readbyqxmd.com/read/29332115/ultrasound-guided-transversus-abdominis-plane-block-postoperative-analgesia-in-children-with-spinal-dysraphism
#1
Eralp Çevikkalp, Koray Erbüyün, Serpil Erbüyün, Gülay Ok
Pediatric regional anesthesia is widely used to relieve postoperative pain after abdominal surgery. Commonly used techniques of regional anesthesia include lumbar epidural and caudal block. However, the use of central neuraxial blockade has limitations. It is contraindicated in patients with clotting abnormalities, spinal dysraphism with tethered cord syndrome, meningomyelocele, and following spinal surgery with instrumentation. Ultrasound guided transversus abdominis plane block is a new method of regional anesthesia that can be used in settings where central neuraxial blockade is contraindicated...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29330929/adipocytes-affect-castration-resistant-prostate-cancer-cells-to-develop-the-resistance-to-cytotoxic-action-of-nk-cells-with-alterations-of-pd-l1-nkg2d-ligand-levels-in-tumor-cells
#2
Lijun Xu, Mingjing Shen, Xiaodong Chen, Rongying Zhu, Dong-Rong Yang, Ying Tsai, Peter C Keng, Yuhchyau Chen, Soo Ok Lee
BACKGROUND: Obesity affects prostate cancer (PCa) progression, and the periprostatic adipose tissue adjacent to the prostate is considered a driving force of disease progression. Adipocytes are the main cell population in adipose tissues and their paracrine role contributes to PCa progression, however its implication in modulating immune reactions remains largely unknown. We investigated the adipocyte role in controlling the susceptibility of castration-resistant PCa (CRPC) cells to the cytotoxic action of natural killer (NK) cells...
January 12, 2018: Prostate
https://www.readbyqxmd.com/read/29328974/novel-approach-for-evaluating-pharmaceuticals-toxicity-using-daphnia-model-analysis-of-the-mode-of-cytochrome-p450-generated-metabolite-action-after-acetaminophen-exposure
#3
Ryeo-Ok Kim, Min-A Jo, Jinhaeng Song, Il-Chan Kim, Seokjoo Yoon, Woo-Keun Kim
Because of its widespread use, the pharmaceutical acetaminophen (APAP) is frequently detected in aquatic environments. APAP can have serious physiological effects, such as reduced reproduction, low growth rates, and abnormal behavior, in aquatic organisms. However, the methods available for evaluation of the aquatic toxicity of APAP are of limited usefulness. The present study aimed to develop reliable and sensitive markers for evaluation of APAP toxicity using Daphnia as a model organism. We focused on N-acetyl-p-benzoquinoneimine (NAPQI) production from APAP via cytochrome P450 metabolism because NAPQI causes APAP toxicity...
December 30, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/29325837/outcomes-of-total-knee-arthroplasty-in-degenerative-osteoarthritic-knee-with-genu-recurvatum
#4
Seung-Suk Seo, Chang-Wan Kim, Chang-Rack Lee, Jin-Hyuk Seo, Do-Hun Kim, Ok-Gul Kim
BACKGROUND: This study aimed to assess the incidence of genu recurvatum without neuromuscular disorders in knees that underwent navigation-assisted total knee arthroplasty (TKA), to evaluate short-term radiologic and clinical results of navigation-assisted TKA in genu recurvatum, and to evaluate differences in results according to the degree of pre-operative hyperextension and type of implant and insert. METHODS: This study retrospectively reviewed 510 knees that underwent navigation-assisted TKA from January 2005 to December 2011...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29325771/a-cross-cultural-study-of-acceptability-and-food-pairing-for-hot-sauces
#5
Hyun-Jee Kim, Seo-Jin Chung, Kwang-Ok Kim, Belinda Nielsen, Rie Ishii, Michael O'Mahony
This study was conducted to understand the acceptance levels of hot sauces among consumers from different culinary cultures. Two newly developed hot sauces [fermented red chili pepper with soybean-paste-based sauce(GS) and fermented red chili-pepper-based sauce(KS)] were compared with Tabasco sauce(TB) and Sriracha sauce(SR). Two separate cross-cultural home-use tests(HUTs) were conducted: pizza and cream soup were provided as food items in HUT 1, whereas grilled chicken wings and rice noodle soup were provided in HUT 2...
January 8, 2018: Appetite
https://www.readbyqxmd.com/read/29324401/unblinded-randomized-multicenter-trial-comparing-lamotrigine-and-valproate-combination-with-controlled-release-carbamazepine-monotherapy-as-initial-drug-regimen-in-untreated-epilepsy
#6
Byung In Lee, Soon Kee No, Sang-Doe Yi, Hyang Woon Lee, Ok Joon Kim, Sang Ho Kim, Myeong Kyu Kim, Sung Eun Kim, Yo Sik Kim, Jae Moon Kim, Se-Jin Lee, Dong Jin Shin, Sung Pa Park, Yeong In Kim, Kyoung Heo, Yong Won Cho, Yang-Je Cho, Youn Nam Kim
PURPOSE: To compare controlled-release carbamazepine monotherapy (CBZ-CR) with lamotrigine and valproate combination therapy (LTG + VPA) in equivalent total drug load, as initial drug regimen in untreated patients with partial and/or generalized tonic-clonic seizures (GTCS). METHODS: This unblinded, randomized, 60-week superiority trial recruited patients having two or more unprovoked seizures with at least one seizure during previous three months. After randomization into CBZ-CR or LTG + VPA, patients entered into eight-week titration phase (TP), followed by 52-week maintenance phase (MP)...
December 29, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29316211/prehypertension-is-a-comorbid-state-with-autonomic-and-metabolic-dysfunction
#7
Mi-Hyang Jung, Sang-Hyun Ihm, Dong-Hyeon Lee, Young Choi, Woo-Baek Chung, Hae Ok Jung, Kyung-Soon Hong, Ho-Joong Youn
We aimed to elucidate the role of autonomic dysfunction in the context of complex metabolic and cardiovascular changes in subjects with prehypertension. We identified 556 asymptomatic subjects without hypertension who underwent comprehensive cardiovascular exams. We obtained heart rate recovery (HRR) after peak exercise to quantitatively measure autonomic dysfunction. Of the 556 participants, 279 individuals had prehypertension and the remaining 277 had optimal BP. HRR was significantly lower in the prehypertension group (36...
January 6, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29315681/statistical-modeling-for-estimating-glucosinolate-content-in-chinese-cabbage-by-growth-conditions
#8
Do-Gyun Kim, Joon-Yong Shim, Myung-Jun Ko, Sun-Ok Chung, Milon Chowdhury, Wang-Hee Lee
BACKGROUND: Glucosinolate in Chinese cabbage (Brassica campestris L. ssp. pekinensis (Lour.) Rupr) has potential benefits for human health, and its content is affected by growth conditions. In this study, we used a statistical model to identify the relationship between glucosinolate content and growth conditions, and to predict glucosinolate content in Chinese cabbage. RESULT: Multiple-regression analysis was employed to develop the model's growth condition parameters of growing period, temperature, humidity, and glucosinolate content measured in Chinese cabbage grown in a plant factory...
January 9, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29311360/myeloid-derived-suppressor-cells-mediate-inflammation-resolution-in-humans-and-mice-with-autoimmune-uveoretinitis
#9
Hyun Jeong Jeong, Hyun Ju Lee, Jung Hwa Ko, Bum-Joo Cho, Se Yeon Park, Jong Woo Park, Se Rang Choi, Jang Won Heo, Sun-Ok Yoon, Joo Youn Oh
Resolution of inflammation is an active process that leads to tissue homeostasis and involves multiple cellular and molecular mechanisms. Myeloid-derived suppressor cells (MDSCs) have recently emerged as important cellular components in the resolution of inflammation because of their activities to suppress T cell activation. In this article, we show that HLA-DR-CD11b+CD33+CD14+ human MDSCs and CD11b+Ly6G-Ly6C+ mouse MDSCs markedly increased in patients and mice during and before the resolution phase of autoimmune uveoretinitis...
January 8, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29311287/comparison-of-a-simple-angiographic-approach-with-a-synergy-between-percutaneous-coronary-intervention-with-taxus-and-cardiac-surgery-score-based-approach-for-left-main-coronary-artery-stenting-a-pooled-analysis-of-serial-precombat-premier-of-randomized-comparison
#10
Pil Hyung Lee, Jong-Young Lee, Cheol Whan Lee, Seon-Ok Kim, Jung-Min Ahn, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Seung-Jung Park
BACKGROUND: The applicability of Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery scores to left main coronary artery disease (CAD) has been questioned. A simplified alternative is needed for guiding decision making. METHODS AND RESULTS: We evaluated the prognostic value of a simplified angiographic classification in comparison with a Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery score-based approach for patients with left main CAD undergoing drug-eluting stent implantation...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29307823/autophagy-mediated-upregulation-of-cytoplasmic-claudin-1-stimulates-the-degradation-of-sqstm1-p62-under-starvation
#11
Jaewhan Kim, Sunkyung Choi, Jong Ok Kim, Kee K Kim
Claudin 1, a major tight junction protein, is highly expressed in various types of tumors such as thyroid, breast, and colorectal cancers. Moreover, claudin 1 is frequently found in the cytoplasm in various types of tumor cells. However, the cytoplasmic function of claudin 1 in tumors still remains largely unknown. Here, we investigated the novel function of cytoplasmic claudin 1 in autophagy. The mRNA expression level of claudin 1 was higher in several types of tumors than in normal tissues. Furthermore, colon tumor tissues showed increased autophagy compared with the adjacent normal tissues...
January 4, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29306534/low-environmental-temperature-influences-the-fatigue-resistance-of-nickel-titanium-files
#12
Ya Shen, Xiangya Huang, Zhejun Wang, Xi Wei, Markus Haapasalo
INTRODUCTION: The purpose of this study was to evaluate the effect of different temperatures (0°C, 10°C, 22°C, 37°C, and 60°C) on the cyclic fatigue life of nickel-titanium (NiTi) files using a new fatigue test model in zirconium oxide. METHODS: Three superelastic NiTi files (EndoSequence [Brasseler USA, Savannah, GA], ProFile [Dentsply Tulsa Dental Specialties, Tulsa, OK], and K3 [SybronEndo, Orange, CA]), and 3 heat-treated (K3XF [SybronEndo], Vortex [Dentsply Tulsa Dental Specialties], and HyFlex CM [Coltene-Whaledent, Allstetten, Switzerland]) NiTi files, all size 25/...
January 3, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29306530/evaluation-of-biocompatibility-and-osteogenic-potential-of-tricalcium-silicate-based-cements-using-human-bone-marrow-derived-mesenchymal-stem-cells
#13
Neha Sultana, Manisha Singh, Ruchika Roongta Nawal, Sarika Chaudhry, Seema Yadav, Sujata Mohanty, Sangeeta Talwar
INTRODUCTION: The success of endodontic regeneration lies in the appropriate combination of stem cells and bioactive materials. Several novel dental materials are available on the market in this regard. Hence, the current study aimed to evaluate the proliferation, differentiation, and osteogenic potential of human bone marrow-derived mesenchymal stem cells (hBMSCs) onto biomaterials like ProRoot MTA (MTA; Dentsply Tulsa Dental, Tulsa, OK), Biodentine (BD; Septodont, Saint Maur de Fosses, France), and EndoSequence Root Repair Material (ERRM; Brasseler USA, Savannah, GA)...
January 3, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29306529/comparison-of-gap-volume-after-retrofilling-using-4-different-filling-materials-evaluation-by-micro-computed-tomography
#14
Sue Youn Kim, Hyeon-Cheol Kim, Su-Jung Shin, Euiseong Kim
INTRODUCTION: The purpose of this study was to evaluate the gap volume between dentin and root-end filling materials. METHODS: Four root-end filling materials were compared in the present study: ProRoot MTA (PRM; Dentsply Tulsa Dental, Tulsa, OK), MTA Angelus (MAG; Angelus, Londrina, Brazil), EndoCem MTA (ECM; Maruchi, Wonju, Korea), and RetroMTA (RTM; BioMTA, Seoul, Korea). Forty-eight single-rooted, extracted human teeth were instrumented with nickel-titanium instruments and oburated with gutta-percha...
January 3, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29306134/production-of-5-hydroxymethylfurfural-from-starch-rich-food-waste-catalyzed-by-sulfonated-biochar
#15
Leichang Cao, Iris K M Yu, Season S Chen, Daniel C W Tsang, Lei Wang, Xinni Xiong, Shicheng Zhang, Yong Sik Ok, Eilhann E Kwon, Hocheol Song, Chi Sun Poon
Sulfonated biochar derived from forestry wood waste was employed for the catalytic conversion of starch-rich food waste (e.g., bread) into 5-hydroxymethylfurfural (HMF). Chemical and physical properties of catalyst were characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) surface area, and elemental analysis. The conversion of HMF was investigated via controlling the reaction parameters such as catalyst loading, temperature, and reaction time...
December 29, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29306075/fasn-tgf-%C3%AE-1-pd-l1-axis-contributes-to-the-development-of-resistance-to-nk-cell-cytotoxicity-of-cisplatin-resistant-lung-cancer-cells
#16
MingJing Shen, Ying Tsai, Rongying Zhu, Peter C Keng, Yongbing Chen, Yuhchyau Chen, Soo Ok Lee
Cisplatin remains the most effective therapy for non-small cell lung cancer (NSCLC). We previously have found cisplatin-resistant lung cancer cells (A549CisR and H157CisR) were more resistant to natural killer (NK) cell-mediated cytotoxicity than parental cells. We also discovered that fatty acid synthase (FASN) levels in cisplatin-resistant cells were significantly higher than parental cells. To reveal whether a link exists between the up-regulated FASN levels and higher resistance to NK cell cytotoxicity, we performed inhibition studies using a FASN inhibitor and applied the FASN knockdown approach...
January 3, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29304090/evaluation-of-a-point-of-care-immunoassay-test-kit-strongstep-for-cryptococcal-antigen-detection
#17
Edward Mpoza, Liliane Mukaremera, Didas Atwebembere Kundura, Andrew Akampurira, Tonny Luggya, Kiiza Kandole Tadeo, Katelyn A Pastick, Sarah C Bridge, Lillian Tugume, Reuben Kiggundu, Abdu K Musubire, Darlisha A Williams, Conrad Muzoora, Elizabeth Nalintya, Radha Rajasingham, Joshua Rhein, David R Boulware, David B Meya, Mahsa Abassi
BACKGROUND: HIV-associated cryptococcal meningitis is the leading cause of adult meningitis in Sub-Saharan Africa, accounting for 15%-20% of AIDS-attributable mortality. The development of point-of-care assays has greatly improved the screening and diagnosis of cryptococcal disease. We evaluated a point-of-care immunoassay, StrongStep (Liming Bio, Nanjing, Jiangsu, China) lateral flow assay (LFA), for cryptococcal antigen (CrAg) detection in cerebrospinal fluid (CSF) and plasma. METHODS: We retrospectively tested 143 CSF and 77 plasma samples collected from HIV-seropositive individuals with suspected meningitis from 2012-2016 in Uganda...
2018: PloS One
https://www.readbyqxmd.com/read/29303239/question-in-patients-with-type-2-diabetes-does-diet-soda-consumption-contribute-to-decline-in-blood-sugar-control
#18
David Hollrah, Kristin Dawson, Patrick Kennedye, Philip Palmer
ANSWER: Insufficient evidence. DATE ANSWER WAS DETERMINED: June 28, 2016. PROGRAM NAME: Great Plains Family Medicine Residency Program, Oklahoma City, OK.
April 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/29302895/correction-to-trace-elements-in-surface-sediments-of-the-hooghly-ganges-estuary-distribution-and-contamination-risk-assessment
#19
Santosh Kumar Sarkar, Priyanka Mondal, Jayanta Kumar Biswas, Eilhann E Kwon, Yong Sik Ok, Jörg Rinklebe
Unfortunately, in the original publication of the article, Prof. Yong Sik Ok's affiliation was incorrectly published. The author's affiliation is as follows.
January 4, 2018: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29302894/correction-to-contrasting-effects-of-engineered-carbon-nanotubes-on-plants-a-review
#20
Meththika Vithanage, Mihiri Seneviratne, Mahtab Ahmad, Binoy Sarkar, Yong Sik Ok
Unfortunately, in the original publication of the article, Prof. Yong Sik Ok's affiliation was incorrectly published. The author's affiliation is as follows.
January 4, 2018: Environmental Geochemistry and Health
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