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https://www.readbyqxmd.com/read/29345970/the-prevalence-and-significance-of-staphylococcus-aureus-in-patients-with-non-cystic-fibrosis-bronchiectasis
#1
Mark L Metersky, Timothy R Aksamit, Alan Barker, Radmila Choate, Charles L Daley, Leigh A Daniels, Angela DiMango, Edward Eden, David Griffith, Margaret Johnson, Michael Knowles, Anne E O'Donnell, Kenneth Olivier, Matthias Salathe, Byron Thomashow, Gregory Tino, Gerard Turino, Kevin L Winthrop, David Mannino
RATIONALE: Staphylococcus aureus is commonly cultured from the sputum of patients with bronchiectasis, however little is known about the prevalence of the organism in these patients, the characteristics of patients who have grown the organism or its implications. OBJECTIVES: Determine the relationship between S. aureus and pulmonary function, frequency of exacerbations and frequency of hospitalization in patients with bronchiectasis Methods: The Bronchiectasis Research Registry is a database of adults with non-cystic fibrosis bronchiectasis identified from 13 sites within the United States...
January 18, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29341323/test-retest-reliability-and-longitudinal-analysis-of-automated-hippocampal-subregion-volumes-in-healthy-ageing-and-alzheimer-s-disease-populations
#2
Amanda Worker, Danai Dima, Anna Combes, William R Crum, Johannes Streffer, Steven Einstein, Mitul A Mehta, Gareth J Barker, Steve C R Williams, Owen O'daly
The hippocampal formation is a complex brain structure that is important in cognitive processes such as memory, mood, reward processing and other executive functions. Histological and neuroimaging studies have implicated the hippocampal region in neuropsychiatric disorders as well as in neurodegenerative diseases. This highly plastic limbic region is made up of several subregions that are believed to have different functional roles. Therefore, there is a growing interest in imaging the subregions of the hippocampal formation rather than modelling the hippocampus as a homogenous structure, driving the development of new automated analysis tools...
January 16, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29336763/methicillin-resistant-staphylococcus-aureus-in-a-trauma-population-does-decolonization-prevent-infection
#3
Robert A Maxwell, Chasen A Croft, C Buddy Creech, Isaac Thomsen, Nicole Soper, Laura E Brown, Vicente A Mejia, Benjamin W Dart, Donald E Barker
The purpose of this study was to determine if a decolonization regimen reduces the frequency of methicillin-resistant Staphylococcus aureus (MRSA) infections and if colonization isolates are genetically related to subsequent infectious strains. Trauma patients admitted to the intensive care unit with positive MRSA nasal swabs were randomized to either daily chlorhexidine gluconate (CHG) baths and mupirocin (MUP) ointment to the nares or soap and water baths and placebo ointment for five days. Nasal swabs performed at the end of treatment and invasive MRSA infections during the remaining hospitalization were compared with the original nasal isolate via polymerase chain reaction for genetic relatedness as well as CHG and MUP resistance genes...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29336689/a-molecular-survey-of-tick-borne-pathogens-from-ticks-collected-in-central-queensland-australia
#4
Melissa Judith Chalada, John Stenos, Gemma Vincent, Dayana Barker, Richard Stewart Bradbury
Central Queensland (CQ) is a large and isolated, low population density, remote tropical region of Australia with a varied environment. The region has a diverse fauna and several species of ticks that feed upon that fauna. This study examined 518 individual ticks: 177 Rhipicephalus sanguineus (brown dog tick), 123 Haemaphysalis bancrofti (wallaby tick), 102 Rhipicephalus australis (Australian cattle tick), 47 Amblyomma triguttatum (ornate kangaroo tick), 57 Ixodes holocyclus (paralysis tick), 9 Bothriocroton tachyglossi (CQ short-beaked echidna tick), and 3 Ornithodoros capensis (seabird soft tick)...
January 16, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29332527/domestic-violence-counseling-in-rural-northern-china-gender-social-harmony-and-human-rights
#5
Lijia Xie, Stephen L Eyre, Judith Barker
Domestic violence (DV) affects over a third of Chinese women in a relationship. Focusing on ethnographic data from six staff members and six DV survivors at a rural, state-affiliated women's center in China in 2010, this article relies on Henrietta Moore's notion of the poststructuralist gendered subject to examine how the staff draw on discourses about gender and social harmony in persuading women to stay in their marriages, rather than on human rights discourses that emphasize survivor safety. It shows that DV survivors are frequently sent back to dangerous homes where their health is placed at risk...
April 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29330859/differential-effects-of-phototherapy-adalimumab-and-betamethasone-calcipotriol-on-effector-and-regulatory-t-cells-in-psoriasis
#6
I S Kotb, B J Lewis, R N Barker, A D Ormerod
BACKGROUND: Psoriasis is a chronic T cell-mediated skin disease with marked social and economic burdens. Current treatments are unsatisfactory, with unpredictable remission times and incompletely understood modes of action. Recent advances in our understanding of the pathogenesis of psoriasis identify the imbalance between CD4+ T effector cells, particularly the T helper (Th) 17 subset, and regulatory T cells (Treg) as key to the development of psoriatic lesions, and therefore a novel therapeutic target...
January 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29330240/structured-management-of-chronic-nonmalignant-pain-with-opioids-in-a-rural-primary-care-office
#7
Kevin S McCann, Shawndra Barker, Raymond Cousins, Adam Franks, Clinton McDaniel, Stephen Petrany, Eric Riley
INTRODUCTION: The use of opioid medication for nonmalignant chronic pain (NMCP) increased dramatically during the last 20 years. There have been regulatory changes implemented to reduce the risk of harm to both patients and society. Much of the burden of monitoring these patients is falling on primary care physicians (PCPs), who do not have the time or resources to handle what is entailed in a best-practice approach to NMCP. METHODS: A retrospective study was conducted with all patients on opioid medication for NMCP who were enrolled onto an individual PCP's practice...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29324695/investigation-into-improving-the-aqueous-solubility-of-the-thieno-2-3-b-pyridine-anti-proliferative-agents
#8
Ayesha Zafar, Lisa I Pilkington, Natalie A Haverkate, Michelle van Rensburg, Euphemia Leung, Sisira Kumara, William A Denny, David Barker, Ali Alsuraifi, Clare Hoskins, Jóhannes Reynisson
It is now established that the thieno[2,3-b]pyridines are a potent class of antiproliferatives. One of the main issues encountered for their clinical application is their low water solubility. In order to improve this, two strategies were pursued. First, a morpholine moiety was tethered to the molecular scaffold by substituting the sulphur atom with nitrogen, resulting in a 1H-pyrrolo[2,3-b]pyridine core structure. The water solubility was increased by three orders of magnitude, from 1.2 µg/mL (1-thieno[2,3-b]pyridine) to 1...
January 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29322223/is-the-timed-loaded-standing-test-a-valid-measure-of-back-muscle-endurance-in-people-with-vertebral-osteoporosis
#9
M Newman, R Newman, T Hughes, K Vadher, K L Barker
Timed loaded standing (TLS) is a suggested measure of back muscle endurance for people with vertebral osteoporosis. Surface electromyography revealed back muscles work harder and fatigue during TLS. The test end-point and total time were associated with back fatigue. The findings help demonstrate the concurrent validity of the TLS test. INTRODUCTION: The TLS test is suggested as a measure of back muscle endurance for patients with vertebral osteoporosis. However, to date, no study has demonstrated that TLS does measure back extensor or erector spinae (ES) muscle endurance...
January 10, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29319920/employee-attitudes-toward-aggression-in-persons-with-dementia-readiness-for-wider-adoption-of-person-centered-frameworks
#10
Vanessa Louise Burshnic, Natalie Douglas, Robert Michael Barker
INTRODUCTION: Implementing person-centered care requires shared attitudes, beliefs, and values among all care employees. Existing research has failed to examine the attitudes of non-nursing employees. AIM: This study examined attitudes toward aggression among nursing and non-nursing employees to address gaps in existing research and assess readiness for wider adoption of person-centered frameworks. METHOD: The Management of Aggression in People with Dementia Attitude Questionnaire was used to survey attitudes of employees in Michigan-based nursing homes...
January 10, 2018: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29317277/increasing-rates-of-surgery-for-patients-with-non-malignant-colorectal-polyps-in-the-united-states
#11
Anne F Peery, Katherine S Cools, Paula D Strassle, Sarah K McGill, Seth D Crockett, Aubrey Barker, Mark Koruda, Ian S Grimm
BACKGROUND & AIMS: Despite the availability of endoscopic therapy, many patients in the United States undergo surgical resection for non-malignant colorectal polyps. We aimed to quantify and examine trends in the use of surgery for non-malignant colorectal polyps in a nationally representative sample. METHODS: We analyzed data from the Healthcare Cost and Utilization Project National Inpatient Sample for the years 2000 through 2014. We included all adult patients who underwent elective colectomy or proctectomy and had a diagnosis of either non-malignant colorectal polyp or colorectal cancer...
January 6, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29316937/estimate-of-incidence-and-cost-of-recreational-waterborne-illness-on-united-states-surface-waters
#12
Stephanie DeFlorio-Barker, Coady Wing, Rachael M Jones, Samuel Dorevitch
BACKGROUND: Activities such as swimming, paddling, motor-boating, and fishing are relatively common on US surface waters. Water recreators have a higher rate of acute gastrointestinal illness, along with other illnesses including respiratory, ear, eye, and skin symptoms, compared to non-water recreators. The quantity and costs of such illnesses are unknown on a national scale. METHODS: Recreational waterborne illness incidence and severity were estimated using data from prospective cohort studies of water recreation, reports of recreational waterborne disease outbreaks, and national water recreation statistics...
January 9, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29309626/examining-the-stability-of-the-hospital-anxiety-and-depression-scale-factor-structure-in-adolescents-and-young-adults-with-cystic-fibrosis-a-confirmatory-factor-analysis
#13
Estefany Saez-Flores, Niza A Tonarely, David H Barker, Alexandra L Quittner
Objective: The Hospital Anxiety and Depression Scale (HADS) is a widely used screening measure of anxiety and depression symptoms. However, prior analyses of the measure have found heterogeneous factor structures and called into question its ability to differentiate between symptoms of anxiety and depression. As part of efforts to implement mental health screening in cystic fibrosis (CF) care, the European Cystic Fibrosis Society (ECFS) and Cystic Fibrosis Foundation (CFF) conducted an international survey of 1,454 CF professionals...
January 3, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29303428/should-social-workers-be-engaged-in-these-practices
#14
Gary Holden, Kathleen Barker
No abstract text is available yet for this article.
January 5, 2018: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/29302616/habitual-behavior-is-mediated-by-a-shift-in-response-outcome-encoding-by-infralimbic-cortex
#15
Jacqueline M Barker, W Bailey Glen, David N Linsenbardt, Christopher C Lapish, L Judson Chandler
The ability to flexibly switch between goal-directed actions and habits is critical for adaptive behavior. The infralimbic prefrontal cortex (IfL-C) has been consistently identified as a crucial structure for the regulation of response strategies. To investigate the role of the IfL-C, the present study employed two validated reinforcement schedules that either promote habits or goal-directed actions in mice. The results reveal that information about action-outcome relationships is differentially encoded in the IfL-C during actions and habits as evidenced by encoding of behavioral outcomes during goal-directed actions that is lost during habits...
November 2017: ENeuro
https://www.readbyqxmd.com/read/29301867/protease-signaling-regulates-apical-cell-extrusion-cell-contacts-and-proliferation-in-epithelia
#16
Antonino Schepis, Adrian Barker, Yoga Srinivasan, Eaman Balouch, Yaowu Zheng, Ian Lam, Hilary Clay, Chung-Der Hsiao, Shaun R Coughlin
Mechanisms that sense and regulate epithelial morphogenesis, integrity, and homeostasis are incompletely understood. Protease-activated receptor 2 (Par2), the Par2-activating membrane-tethered protease matriptase, and its inhibitor, hepatocyte activator inhibitor 1 (Hai1), are coexpressed in most epithelia and may make up a local signaling system that regulates epithelial behavior. We explored the role of Par2b in matriptase-dependent skin abnormalities in Hai1a-deficient zebrafish embryos. We show an unexpected role for Par2b in regulation of epithelial apical cell extrusion, roles in regulating proliferation that were opposite in distinct but adjacent epithelial monolayers, and roles in regulating cell-cell junctions, mobility, survival, and expression of genes involved in tissue remodeling and inflammation...
January 4, 2018: Journal of Cell Biology
https://www.readbyqxmd.com/read/29301183/north-korean-children-nutrition-and-growth
#17
REVIEW
Soo-Kyung Lee
North Korea suffered from severe famine in the mid-1990s; this impacted many areas, including people's transnational movement, child growth, and mortality. This review carefully examined nutritional status trends of children in North Korea using published reports from national nutrition assessment surveys. Nutritional adaptation of North Korean child refugees living in South Korea was also studied with their growth and food consumption, using published researches. The nutritional status of children in North Korea has recovered to a "low" level acute malnutrition status and a "medium" level chronic malnutrition status...
December 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29300047/stem-cells-in-2017-digesting-recent-stem-cell-advances-in-the-gut
#18
Nick Barker
No abstract text is available yet for this article.
January 4, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29299978/psychological-support-for-sport-coaches-an-exploration-of-practitioner-psychologist-perspectives
#19
Sarah Kelly, Richard Thelwell, Jamie B Barker, Chris G Harwood
In the present study we add to the literature by exploring the degree to which UK practitioner psychologists perceive themselves able to support sport coaches, and how professional training prepares psychologists for coach work across performance domains. Ten participants comprising seven sport and exercise psychologists with Health Care Professions Council (HCPC) practitioner psychologist status and three trainee psychologists studying towards the British Psychological Society (BPS) qualification in sport and exercise psychology (QSEP) were individually interviewed...
January 4, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29299392/rapid-neurophysiological-screening-for-sensory-ganglionopathy-a-novel-approach
#20
Panagiotis Zis, Marios Hadjivassiliou, Ptolemaios Georgios Sarrigiannis, Alexander St John Edward Barker, Dasappaiah Ganesh Rao
Background and Aim: Pure sensory neuropathies involving the dorsal root ganglia are commonly referred to as sensory ganglionopathies (SG). Causes of SG can be inherited (as seen in Friedreich's ataxia) or acquired (e.g. immune-mediated or paraneoplastic). Diagnostic criteria for confirming SG have been published and consist of a combination of clinical and neurophysiological parameters. The aim of our study was to develop a neurophysiological method for rapid screening for diagnosis of SG...
December 2017: Brain and Behavior
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