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Dibetes

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https://www.readbyqxmd.com/read/25207077/evaluation-of-the-effects-of-novel-nafimidone-derivatives-on-thermal-hypoalgesia-in-mice-with-diabetic-neuropathy
#1
Suat Kamışlı, Arzu Karakurt, Ayşe B Uyumlu, Basri Satılmış, Abdullah Alagöz, Metin F Genç, Kadir Batcıoğlu
OBJECTIVE: Diabetic neuropathy (DN) is a common complication in Diabetes Mellitus. The streptozotocin-induced diabetic rodent is the most commonly used animal model of diabetes and increased sodium channel expression and activity were revealed in this model. At this study, we evaluated the effect of three different nafimidone derivatives which have possible anticonvulsant activity on disorders of thermal pain sensation in diabetic mice. STUDY DESIGN: Randomized animal experiment...
March 2013: Balkan Medical Journal
https://www.readbyqxmd.com/read/24527588/-prevalence-of-diabetes-and-impaired-glucose-regulation-in-chengdu-populations-and-associated-dietary-risk-factors
#2
Hua Dai, Li-Yu Chen, Shuang-Qing Li
OBJECTIVE: To determine the prevalence of type 2 DM and impaired glucose regulation (IGR) in Chengdu populations and to identify dietary risk factors associated with DM and IGR. METHODS: Two communities in Chengdu were selected for this study. Fasting blood-glucose (FBG) and 2-hour post-meal blood glucose (2 hGlu) tests were performed in the community residents. The participants were asked to complete a questionair recording their daily food intaking. The total calorie of food, percentage of different kinds of food, and intake of electrolyte, vietamine and micro minerals were calculated and compared between those with and without type 2 DM or IGR...
January 2014: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/23781448/a-validated-rp-hplc-method-for-quantitation-of-trigonelline-from-herbal-formulations-containing-trigonella-foenum-graecum-l-seeds
#3
Sunita Shailajan, Sasikumar Menon, Ashish Singh, Mandar Mhatre, Neelam Sayed
BACKGROUND: Trigonella foenum-graecum (L.) (Fabaceae, Fenugreek) is an important ingredient of Ayurvedic and other marketed herbal formulations. Fenugreek seeds are employed in many traditional systems as an antibacterial and antidiabetic agent, gastric stimulant and galactogogue. Trigonelline, a major phytoconstituent found in fenugreek seeds, shows estrogenic, anti-diabetic and anti-invasive activity. Therefore, it is a suitable bioactive marker to establish the quality of crude drug and its formulations...
July 2011: Pharmaceutical Methods
https://www.readbyqxmd.com/read/21778651/-epidemiological-study-on-hba1c-level-below-6-1-among-community-residents-and-follow-up-study-of-hba1c-level-clinical-significance-of-health-examination-japan-in-the-aged-members-from-the-view-point-of-glucose-metabolism
#4
Shunji Imanaka
AIM: This study is to investigate whether the set point of HbA1c being 5.2% or more is too strict a line to be drawn by Tokutei-kensin (Health Examination for metabolic syndrome in Japan) on people 65 years old or more from the view point of glucose metabolism. METHODS: Samples were out-patients of the community clinic and community residents from the jurisdiction of the community clinic. (1) Epidemiological data on those who were in their 50s, 60s and 70s with HbA1c level between 5...
2011: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/15934303/effect-of-calcium-dobesilate-on-nephropathy-in-type-2-diabetic-rats
#5
Xiaocheng Liu, Xinming Liu
In order to investigate the effects and mechanisms of calcium dobesilate on renal lesions in experimental type 2 diabetic rats, dibetic rats were randomly divided into control group (group C) and experimental group (group D) treated with calcium dobesitate. The serum creatinine (Scr), protein kinase C (PKC), creatinine clearance (Ccr), transforming growth factor-beta, (TGF-beta1), type IV collagen were compared among the groups after 24 weeks. The renal tissues were observed under light microscopy and electron microscopy...
2005: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/15826438/understanding-of-blood-pressure-by-people-with-type-2-diabetes-a-primary-care-focus-group-study
#6
RANDOMIZED CONTROLLED TRIAL
Jane Stewart, Ken Brown, Denise Kendrick, Jane Dyas
BACKGROUND: For many people with type 2 diabetes most care is provided in primary care. While people with both diabetes and hypertension are at increased risk of complications, little is known about their understanding of blood pressure. AIM: To explore the understanding and beliefs about the importance of blood pressure held by people with type 2 diabetes. DESIGN OF STUDY: Framework analysis of qualitative research using focus groups. SETTING: Thirty-two participants were recruited from four general practices and a religious meeting group in Nottingham...
April 2005: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/14227396/-diabetes-prevention-complications-of-dibetes
#7
J A DELBARCOCALZADILLA
No abstract text is available yet for this article.
September 1964: Hispalis Médica; Revista Sevillana de Medicina y Cirugia
https://www.readbyqxmd.com/read/12458487/prevention-of-experimental-diabetic-cataract-by-indian-ayurvedic-plant-extracts
#8
S S Rathi, J K Grover, Vats Vikrant, N R Biswas
The efficacy of Momordica charantia (MC), Eugenia jambolana (EJ), Tinospora cordifolia (TC) and Mucuna pruriens (MP) was assessed in the prevention of murine alloxan dibetic cataract. Alloxan (120 mg/kg) was used as the diabetogenic agent. While controls and diabetic controls did not receive any plant extract, treated rats received lyophilized aqueous extract of MC and EJ (200 mg/kg p.o.), alcohol extract of TC (400 mg/kg) and MP (200 mg/kg p.o.) every day until 4 months. Serum glucose concentration was assessed and cataracts examined with both the naked eye and through a slit lamp...
December 2002: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/11724421/geographical-variation-of-presentation-at-diagnosis-of-type-i-diabetes-in-children-the-eurodiab-study-european-and-dibetes
#9
C Lévy-Marchal, C C Patterson, A Green
AIMS/HYPOTHESIS: We aimed to describe the frequency and degree of diabetic ketoacidosis in children across Europe at the time of diagnosis of Type I (insulin-dependent) diabetes mellitus and to determine if factors such as age and geographical region contribute to the risk of diabetic ketoacidosis. METHODS: The study was part of the EURODIAB project. A total of 24 centres, covering a population at risk of more than 15 million children below 15 years of age, recruited 1,260 children at the time of clinical diagnosis...
October 2001: Diabetologia
https://www.readbyqxmd.com/read/10513348/atopy-parameters-in-asthmatic-infants
#10
A Tridon, J L Fauquert, P Dibet, G Betail, A Labbe
We evaluated various atopy parameters in 44 asthmatic infants aged 1-3 years: nonspecific parameters (total IgE and eosinophilia), and specific parameters relative to 21 allergens (specific IgE and skin tests), together with tests of leukotriene release by blood leukocytes (cellular allergen stimulation test; CAST) in the presence of a mixture of 21 allergens. Thus far 17 infants have displayed no sign of atopy, but 27 met at least one criterion. Eight met nonspecific criteria, and the others single or multiple criteria...
July 1999: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/9296077/-mixed-cryoglobulins-and-autoimmunity-in-hepatitis-c
#11
A Tridon, A Abergel, P Kuder, C Henquell, H Malaure, P Dibet, J Ghrib, G Bommelaer, G Bétail
We explored and studied cryoglobulins and autoantibodies in 149 patients with hepatitis C. 49% of untreated patients have cryoglobuliemia (36% polyclonal cryoglobulins) and 76% of ineffectively treated patients since more than 6 months (50% polyclonal cryoglobulins). Other observed cryoglobulins are half of type II and half oligoclonal. In 22 cryoglobulinemic patients before treatment, a good clinical response to IFN is induced only among patients for which cryoglobulins are negative at the end of treatment...
April 1997: Pathologie-biologie
https://www.readbyqxmd.com/read/8952663/-cold-agglutinins-and-cryoglobulinemia-in-a-patient-with-hepatitis-c
#12
M Ruivard, A Tridon, F Quainon, V Rieu, A C Fouilhoux, P Dibet, C Henquell, G Bétail, P Philippe, J D Tissot
OBJECTIVES: Cold agglutinins and cryoglobulins are uncommon in the same patient as observed in our case. CASE REPORT: A 74-year-old patient suffered repeated episodes of hemolytic anemia for one year and had hepatitis C anti-virus antibodies. Mixed cryoglobulinemia was found at levels which increased during episodes of acute hemolysis in addition to anti-I cold agglutinins. Two-dimensional electrophoresis revealed identical oligoclonal cold agglutinins and cryoglobulins...
October 26, 1996: La Presse Médicale
https://www.readbyqxmd.com/read/8247631/-detection-and-analysis-of-cryoglobulins-comparative-study-of-a-population-of-patients-and-one-of-healthy-controls
#13
COMPARATIVE STUDY
J P Romaszko, A Tridon, P Jouanel, E Subtil, P Dibet, G Betail
During an 11-month period, 270 cryoglobulins were identified in 735 sera from patients versus 34 in 82 sera from apparently healthy blood donors. Western-blot analysis of the cryoglobulins was performed and cryoglobulin protein content was determined using a colorimetric assay. Comparison of findings in the two groups suggested that a substantial proportion of cryoglobulins identified in the sera of patients are quantitatively and qualitatively indistinguishable from cryoglobulins identified in healthy controls...
June 1993: Pathologie-biologie
https://www.readbyqxmd.com/read/2052422/-mixed-cryoglobulins-and-heterogeneity-restriction
#14
A Tridon, C Romazko, P Dibet, G Bétail
Cryoglobulins from 143 patients were analyzed using an immunoblot technique with a nitrocellulose membrane. Fifty-four p. cent of cases were classified as type III, with polyclonal IgG, IgA, and IgM being the most common components. Type II was found in 24% of cases, with a monoclonal IgM in most instances. Lastly, classification was impossible in 22% of cases, usually because of the presence of oligoclonal IgM bands. Use of this highly sensitive technique to analyse cryoglobulins raises the problem of identification of patterns that are difficult to include in types II and III...
March 1991: Pathologie-biologie
https://www.readbyqxmd.com/read/1175310/plasma-glucagon-response-to-arginine-infusion-in-children-and-adolescents-with-diabetes-mellitus
#15
Z Josefsberg, Z Laron, M Doron, R Keret, Y Belinski, I Weismann
Plasma glucagon response to an arginine infusion was studied in children and adolescents belonging to the following groups: (I) twenty-two controls; (II) six subjects with delayed insulin peak during oral GTT; (III) ten diabetics on diet and/or oral therapy; (IV) six newly diagnosed uncompensated diabetics; and (V) eight diabetics on insulin therapy. The fasting glucagon concentrations and rise of glucagon in response to arginine in the patients of Groups II, III and V were similar to those of the controls (Group I)...
September 1975: Clinical Endocrinology
https://www.readbyqxmd.com/read/631458/the-effect-of-insulin-on-pyruvate-dehydrogenase-interconversion-in-heart-muscle-of-alloxan-diabetic-rats
#16
J Ohlen, E A Siess, G Löffler, O H Wieland
Evidence is presented for regulation by insulin of pyruvate dehydrogenase (pdh) interconversion in rat heart muscle in vivo and in vitro. In the alloxan diabetic rat the active (dephospho) enzyme amounted only to 12% of total PDH and was restored to 42% by insulin. Antilipolytic treatment of the dibetic animals was ineffective, indicating that the action of insulin was independent of a lowering of plasma non-esterified fatty acid concentration. On perfusion of isolated hearts from diabetic rats in the presence of glucose the proportion of pyruvate dehydrogenase in the active form remained low but was fully restored upon addition of insulin (2mU/ml) to the medium...
February 1978: Diabetologia
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